Isolated polynucleotides and polypeptides, and methods of using same for increasing plant yield, biomass, vigor and/or growth rate of a plant

ABSTRACT

Provided are isolated polynucleotides which comprise a nucleic acid sequence at least 80% identical to SEQ ID NO: 3487, or 7; isolated polypeptides which comprise an amino acid sequence at least 80% homologous to SEQ ID NO: 246, and and methods of using same for increasing a yield, biomass, growth rate, vigor, and/or oil content, of a plant.

RELATED APPLICATIONS

This application is a National Phase of PCT Patent Application No.PCT/IB2010/050871 having International filing date of Mar. 1, 2010,which claims the benefit of priority of U.S. Provisional PatentApplication Nos. 61/282,183 filed on Dec. 28, 2009, 61/231,349 filed onAug. 5, 2009 and 61/202,459 filed on Mar. 2, 2009. The contents of theabove applications are all incorporated herein by reference.

FIELD AND BACKGROUND OF THE INVENTION

The present invention, in some embodiments thereof, relates to isolatedpolynucleotides and polypeptides which can increase the yield (e.g.,biomass, grain quantity and/or quality), growth rate, vigor, abioticstress tolerance (ABST), water use efficiency (WUE), nitrogen useefficiency (NUE) and/or fertilizer use efficiency (FUE) of a plant.

The ever-increasing world population and the decreasing availability inarable land for agriculture affect the yield of plants and plant-relatedproducts. The global shortage of water supply, desertification, abioticstress (ABS) conditions (e.g., salinity, drought, flood, suboptimaltemperature and toxic chemical pollution), and/or limited nitrogen andfertilizer sources cause substantial damage to agricultural plants suchas major alterations in the plant metabolism, cell death, and decreasesin plant growth and crop productivity.

Drought is a gradual phenomenon, which involves periods of abnormallydry weather that persists long enough to produce serious hydrologicimbalances such as crop damage, water supply shortage and increasedsusceptibility to various diseases.

Salinity, high salt levels, affects one in five hectares of irrigatedland. None of the top five food crops, i.e., wheat, corn, rice,potatoes, and soybean, can tolerate excessive salt. Detrimental effectsof salt on plants result from both water deficit, which leads to osmoticstress (similar to drought stress), and the effect of excess sodium ionson critical biochemical processes. As with freezing and drought, highsalt causes water deficit; and the presence of high salt makes itdifficult for plant roots to extract water from their environment. Thus,salination of soils that are used for agricultural production is asignificant and increasing problem in regions that rely heavily onagriculture, and is worsen by over-utilization, over-fertilization andwater shortage, typically caused by climatic change and the demands ofincreasing population.

Suboptimal temperatures affect plant growth and development through thewhole plant life cycle. Thus, low temperatures reduce germination rateand high temperatures result in leaf necrosis. In addition, matureplants that are exposed to excess heat may experience heat shock, whichmay arise in various organs, including leaves and particularly fruit,when transpiration is insufficient to overcome heat stress. Heat alsodamages cellular structures, including organelles and cytoskeleton, andimpairs membrane function. Heat shock may produce a decrease in overallprotein synthesis, accompanied by expression of heat shock proteins,e.g., chaperones, which are involved in refolding proteins denatured byheat. High-temperature damage to pollen almost always occurs inconjunction with drought stress, and rarely occurs under well-wateredconditions. Combined stress can alter plant metabolism in novel ways.Excessive chilling conditions, e.g., low, but above freezing,temperatures affect crops of tropical origins, such as soybean, rice,maize, and cotton. Typical chilling damage includes wilting, necrosis,chlorosis or leakage of ions from cell membranes. Excessive lightconditions, which occur under clear atmospheric conditions subsequent tocold late summer/autumn night's, can lead to photoinhibition ofphotosynthesis (disruption of photosynthesis). In addition, chilling maylead to yield losses and lower product quality through the delayedripening of maize.

Suboptimal nutrient (macro and micro nutrient) affect plant growth anddevelopment through the whole plant life cycle. One of the essentialmacronutrients for the plant is Nitrogen. Nitrogen is responsible forbiosynthesis of amino acids and nucleic acids, prosthetic groups, planthormones, plant chemical defenses, and the like. Nitrogen is often therate-limiting element in plant growth and all field crops have afundamental dependence on inorganic nitrogenous fertilizer. Sincefertilizer is rapidly depleted from most soil types, it must be suppliedto growing crops two or three times during the growing season.Additional important macronutrients are Phosphorous (P) and Potassium(K), which have a direct correlation to yield and general planttolerance.

Yield is affected by various factors, such as, the number and size ofthe plant organs, plant architecture (for example, the number ofbranches), grains set length, number of filled grains, vigor (e.g.seedling), growth rate, root development, utilization of water,nutrients (e.g., nitrogen) and fertilizers, and stress tolerance.

Crops such as, corn, rice, wheat, canola and soybean account for overhalf of total human caloric intake, whether through direct consumptionof the seeds themselves or through consumption of meat products raisedon processed seeds or forage. Seeds are also a source of sugars, oilsand metabolites used in industrial processes. The ability to increaseplant yield, whether through increase dry matter accumulation rate,modifying cellulose or lignin composition, increase stalk strength,enlarge meristem size, change of plant branching pattern, erectness oflevees, increase in fertilization efficiency, enhanced seed dry matteraccumulation rate, modification of seed development, enhanced seedfilling or by increasing the content of oil, starch or protein in theseeds would have many applications in agricultural and non-agriculturaluses such as in the biotechnological production of pharmaceuticals,antibodies or vaccines.

Studies have shown that plant adaptations to adverse environmentalconditions are complex genetic traits with polygenic nature.Conventional means for crop and horticultural improvements utilizeselective breeding techniques to identify plants having desirablecharacteristics. However, selective breeding is tedious, time consumingand has an unpredictable outcome. Furthermore, limited germplasmresources for yield improvement and incompatibility in crosses betweendistantly related plant species represent significant problemsencountered in conventional breeding. Advances in genetic engineeringhave allowed mankind to modify the germplasm of plants by expression ofgenes-of-interest in plants. Such a technology has the capacity togenerate crops or plants with improved economic, agronomic orhorticultural traits.

WO publication No. 2009/013750 discloses genes, constructs and methodsof increasing abiotic stress tolerance, biomass and/or yield in plantsgenerated thereby.

WO publication No. 2008/122980 discloses genes constructs and methodsfor increasing oil content, growth rate and biomass of plants.

WO publication No. 2008/075364 discloses polynucleotides involved inplant fiber development and methods of using same.

WO publication No. 2007/049275 discloses isolated polypeptides,polynucleotides encoding same, transgenic plants expressing same andmethods of using same for increasing plant abiotic stress tolerance andbiomass.

WO publication No. 2004/104162 discloses methods of increasing abioticstress tolerance and/or biomass in plants and plants generated thereby.

WO publication No. 2005/121364 discloses polynucleotides andpolypeptides involved in plant fiber development and methods of usingsame for improving fiber quality, yield and/or biomass of a fiberproducing plant.

WO publication No. 2007/020638 discloses methods of increasing abioticstress tolerance and/or biomass in plants and plants generated thereby.

SUMMARY OF THE INVENTION

According to an aspect of some embodiments of the present inventionthere is provided a method of increasing yield, biomass, growth rate,vigor, oil content, fiber yield, fiber quality, abiotic stresstolerance, and/or nitrogen use efficiency of a plant, comprisingexpressing within the plant an exogenous polynucleotide comprising anucleic acid sequence at least 80% identical to SEQ ID NO: 3487, 1-239,467-1973, 3481-3486, 3488-3674, 3738 or 3739, thereby increasing theyield, biomass, growth rate, vigor, oil content, fiber yield, fiberquality, abiotic stress tolerance, and/or nitrogen use efficiency of theplant.

According to an aspect of some embodiments of the present inventionthere is provided a method of increasing yield, biomass, growth rate,vigor, oil content, fiber yield, fiber quality, abiotic stresstolerance, and/or nitrogen use efficiency of a plant, comprisingexpressing within the plant an exogenous polynucleotide comprising thenucleic acid sequence selected from the group consisting of SEQ ID NOs:3487, 1-239, 467-1973, 3481-3486, 3488-3674, and 3738-3739, therebyincreasing the yield, biomass, growth rate, vigor, oil content, fiberyield, fiber quality, abiotic stress tolerance, and/or nitrogen useefficiency of the plant.

According to an aspect of some embodiments of the present inventionthere is provided a method of increasing yield, biomass, growth rate,vigor, oil content, fiber yield, fiber quality, abiotic stresstolerance, and/or nitrogen use efficiency of a plant, comprisingexpressing within the plant an exogenous polynucleotide comprising anucleic acid sequence encoding a polypeptide at least 80% identical toSEQ ID NO: 246, 240-245, 247-465, 1974-3480, 3675-3736 or 3737, therebyincreasing the yield, biomass, growth rate, vigor, oil content, fiberyield, fiber quality, abiotic stress tolerance, and/or nitrogen useefficiency of the plant.

According to an aspect of some embodiments of the present inventionthere is provided a method of increasing yield, biomass, growth rate,vigor, oil content, fiber yield, fiber quality, abiotic stresstolerance, and/or nitrogen use efficiency of a plant, comprisingexpressing within the plant an exogenous polynucleotide comprising anucleic acid sequence encoding a polypeptide selected from the groupconsisting of SEQ ID NOs: 246, 240-245, 247-465, 1974-3480, and3675-3737, thereby increasing the yield, biomass, growth rate, vigor,oil content, fiber yield, fiber quality, abiotic stress tolerance,and/or nitrogen use efficiency of the plant.

According to an aspect of some embodiments of the present inventionthere is provided an isolated polynucleotide comprising a nucleic acidsequence at least 80% identical to SEQ ID NO: 3487, 1-239, 467-1973,3481-3486, 3488-3674, 3738 or 3739, wherein said nucleic acid sequenceis capable of increasing yield, biomass, growth rate, vigor, oilcontent, fiber yield, fiber quality, abiotic stress tolerance, and/ornitrogen use efficiency of a plant.

According to an aspect of some embodiments of the present inventionthere is provided an isolated polynucleotide comprising the nucleic acidsequence selected from the group consisting of SEQ ID NOs: 3487, 1-239,467-1973, 3481-3486, 3488-3674, and 3738-3739.

According to an aspect of some embodiments of the present inventionthere is provided an isolated polynucleotide comprising a nucleic acidsequence encoding a polypeptide which comprises an amino acid sequenceat least 80% homologous to the amino acid sequence set forth in SEQ IDNO: 246, 240-245, 247-465, 1974-3480, 3675-3736 or 3737, wherein saidnucleic acid sequence is capable of increasing yield, biomass, growthrate, vigor, oil content, fiber yield, fiber quality, abiotic stresstolerance, and/or nitrogen use efficiency of a plant.

According to an aspect of some embodiments of the present inventionthere is provided an isolated polynucleotide comprising a nucleic acidsequence encoding a polypeptide which comprises the amino acid sequenceselected from the group consisting of SEQ ID NOs: 246, 240-245, 247-465,1974-3480, and 3675-3737.

According to an aspect of some embodiments of the present inventionthere is provided a nucleic acid construct comprising the isolatedpolynucleotide of claim 5, 6, 7 or 8, and a promoter for directingtranscription of said nucleic acid sequence in a host cell.

According to an aspect of some embodiments of the present inventionthere is provided an isolated polypeptide comprising an amino acidsequence at least 80% homologous to SEQ ID NO: 246, 240-245, 247-465,1974-3480, 3675-3736 or 3737, wherein said amino acid sequence iscapable of increasing yield, biomass, growth rate, vigor, oil content,fiber yield, fiber quality, abiotic stress tolerance, and/or nitrogenuse efficiency of a plant.

According to an aspect of some embodiments of the present inventionthere is provided an isolated polypeptide comprising the amino acidsequence selected from the group consisting of SEQ ID NOs: 246, 240-245,247-465, 1974-3480, and 3675-3737.

According to an aspect of some embodiments of the present inventionthere is provided a plant cell exogenously expressing the polynucleotideof claim 5, 6, 7 or 8 or the nucleic acid construct of claim 9.

According to an aspect of some embodiments of the present inventionthere is provided a plant cell exogenously expressing the polypeptide ofclaim 10 or 11.

According to some embodiments of the invention, the nucleic acidsequence is as set forth in SEQ ID NO: 3487, 1-239, 467-1973, 3481-3486,3488-3674, 3738 or 3739.

According to some embodiments of the invention, the polynucleotideconsists of the nucleic acid sequence selected from the group consistingof SEQ ID NOs: 3487, 1-239, 467-1973, 3481-3486, 3488-3674, and3738-3739.

According to some embodiments of the invention, the nucleic acidsequence encodes an amino acid sequence at least 80% homologous to SEQID NO: 246, 240-245, 247-465, 1974-3480, 3675-3736 or 3737.

According to some embodiments of the invention, the nucleic acidsequence encodes the amino acid sequence selected from the groupconsisting of SEQ ID NOs: 246, 240-245, 247-465, 1974-3480, and3675-3737.

According to some embodiments of the invention, the plant cell forms apart of a plant.

According to some embodiments of the invention, the abiotic stress isselected from the group consisting of salinity, drought, waterdeprivation, low temperature, high temperature, heavy metal toxicity,anaerobiosis, nutrient deficiency, nutrient excess, atmosphericpollution and UV irradiation.

According to some embodiments of the invention, the method furthercomprising growing the plant under the abiotic stress.

According to some embodiments of the invention, the method, furthercomprising growing the plant under nitrogen-limiting conditions.

Unless otherwise defined, all technical and/or scientific terms usedherein have the same meaning as commonly understood by one of ordinaryskill in the art to which the invention pertains. Although methods andmaterials similar or equivalent to those described herein can be used inthe practice or testing of embodiments of the invention, exemplarymethods and/or materials are described below. In case of conflict, thepatent specification, including definitions, will control. In addition,the materials, methods, and examples are illustrative only and are notintended to be necessarily limiting.

BRIEF DESCRIPTION OF THE DRAWINGS

Some embodiments of the invention are herein described, by way ofexample only, with reference to the accompanying drawings. With specificreference now to the drawings in detail, it is stressed that theparticulars shown are by way of example and for purposes of illustrativediscussion of embodiments of the invention. In this regard, thedescription taken with the drawings makes apparent to those skilled inthe art how embodiments of the invention may be practiced.

In the drawings:

FIG. 1 is a schematic illustration of the modified pGI binary plasmidcontaining the new At6669 promoter (SEQ ID NO:4198) and the GUSintron(pQYN_(—)6669) used for expressing the isolated polynucleotide sequencesof the invention. RB—T-DNA right border; LB—T-DNA left border;MCS—Multiple cloning site; RE—any restriction enzyme; NOS pro=nopalinesynthase promoter; NPT-II=neomycin phosphotransferase gene; NOSter=nopaline synthase terminator; Poly-A signal (polyadenylationsignal); GUSintron—the GUS reporter gene (coding sequence and intron).The isolated polynucleotide sequences of the invention were cloned intothe vector while replacing the GUSintron reporter gene.

FIG. 2 is a schematic illustration of the modified pGI binary plasmidcontaining the new At6669 promoter (SEQ ID NO:4198) (pQFN) used forexpressing the isolated polynucleotide sequences of the invention.RB—T-DNA right border; LB—T-DNA left border; MCS—Multiple cloning site;RE—any restriction enzyme; NOS pro=nopaline synthase promoter;NPT-II=neomycin phosphotransferase gene; NOS ter=nopaline synthaseterminator; Poly-A signal (polyadenylation signal); GUSintron—the GUSreporter gene (coding sequence and intron). The isolated polynucleotidesequences of the invention were cloned into the MCS of the vector.

FIGS. 3A-F are images depicting visualization of root development oftransgenic plants exogenously expressing the polynucleotide of someembodiments of the invention when grown in transparent agar plates undernormal (FIGS. 3A-B), osmotic stress (15% PEG; FIGS. 3C-D) ornitrogen-limiting (FIGS. 3E-F) conditions. The different transgenes weregrown in transparent agar plates for 17 days (7 days nursery and 10 daysafter transplanting). The plates were photographed every 3-4 daysstarting at day 1 after transplanting. FIG. 3A—An image of a photographof plants taken following 10 after transplanting days on agar plateswhen grown under normal (standard) conditions. FIG. 3B—An image of rootanalysis of the plants shown in FIG. 3A in which the lengths of theroots measured are represented by arrows. FIG. 3C—An image of aphotograph of plants taken following 10 days after transplanting on agarplates, grown under high osmotic (PEG 15%) conditions. FIG. 3D—An imageof root analysis of the plants shown in FIG. 3C in which the lengths ofthe roots measured are represented by arrows. FIG. 3E—An image of aphotograph of plants taken following 10 days after transplanting on agarplates, grown under low nitrogen conditions. FIG. 3F—An image of rootanalysis of the plants shown in FIG. 3E in which the lengths of theroots measured are represented by arrows.

DESCRIPTION OF SPECIFIC EMBODIMENTS OF THE INVENTION

The present invention, in some embodiments thereof, relates to isolatedpolynucleotides and polypeptides which can increase yield, biomass,growth rate, vigor, oil content, fiber yield, fiber quality abioticstress tolerance, and/or fertilizer use efficiency (e.g., nitrogen useefficiency) of a plant.

Before explaining at least one embodiment of the invention in detail, itis to be understood that the invention is not necessarily limited in itsapplication to the details set forth in the following description orexemplified by the Examples. The invention is capable of otherembodiments or of being practiced or carried out in various ways.

The present inventors have identified novel polynucleotides andpolypeptides which can be used in increasing yield, biomass, growthrate, vigor, oil content, fiber yield, fiber quality abiotic stresstolerance, and/or fertilizer use efficiency (e.g., nitrogen useefficiency) of a plant.

As shown in the Examples section which follows, the present inventorshave employed a bioinformatic approach which combines clustering andassembly of sequences from databases of arabidopsis, rice, poplar,brachypodium, soybean, grape, castobean, sorghum and maize and otherpublicly available plant genomes, expressed sequence tags (ESTs), mRNAsequences, properitary ESTs sequences (Barley, Sorghum), protein andpathway databases, quantitative trait loci (QTL), single nucleotidepolymorphism (SNPs) information with a digital expression profile(“electronic Northern Blot”) and identified polynucleotides andpolypeptides which can increase yield, growth rate, biomass, vigor,tolerance to abiotic stress, nitrogen use efficiency, water useefficiency and fertilizer use efficiency (SEQ ID NOs:1-239 forpolynucleotides; SEQ ID NOs:240-465 for polypeptides; Table 1, Example1). Orthologs from plant species which exhibit at least 80% homology tothe identified polypeptides and polynucleotides were also identified(SEQ ID NO:467-1973 for polynucleotides; SEQ ID NOs:1974-3480 forpolypeptides; Table 2, Example 1). Selected genes were cloned (Example7, Tables 26-28), transformed into agrobacterium tumefaciens cells(Example 8) and further into arabidopsis plants (Example 9). Transgenicplants over-expressing the identified polynucleotides were found toexhibit increased seed yield, oil yield, dry weight, fresh weight, rootcoverage, root length, harvest index, growth rate, rosette area,biomass, oil percentage in seed and weight of 1000 seeds (Examples10-11; Tables 29-36), and increased tolerance to abiotic stressconditions such as limiting nitrogen conditions (Example 11, Tables37-38). Thus, the identified polynucleotides and polypeptides of theinvention can be used to increase plant's yield, biomass (e.g., of grainor any harvestable plant part with economical value), vigor, growthrate, oil content, fiber yield, fiber quality, tolerance to abioticstress, nitrogen use efficiency, water use efficiency and/or fertilizeruse efficiency.

Thus, according to an aspect of some embodiments of the invention thereis provided a method of increasing a yield, biomass, growth rate, vigor,oil content, fiber yield, fiber quality, water use efficiency, nitrogenuse efficiency, fertilizer use efficiency and/or abiotic stresstolerance of a plant.

The method is effected by expressing within the plant an exogenouspolynucleotide comprising a nucleic acid sequence at least 80% identicalto SEQ ID NO: 3487, 1-239, 467-1973, 3481-3486, 3488-3674, 3738 or 3739,thereby increasing the yield, biomass, growth rate, vigor, oil content,fiber yield, fiber quality, water use efficiency, nitrogen useefficiency, fertilizer use efficiency and/or abiotic stress tolerance ofthe plant.

As used herein the phrase “plant yield” refers to the amount (e.g., asdetermined by weight or size) or quantity (numbers) of tissues or organsproduced per plant or per growing season. Hence increased yield couldaffect the economic benefit one can obtain from the plant in a certaingrowing area and/or growing time.

It should be noted that a plant yield can be affected by variousparameters including, but not limited to, plant biomass; plant vigor;growth rate; seed yield; seed or grain quantity; seed or grain quality;oil yield; content of oil, starch and/or protein in harvested organs(e.g., seeds or vegetative parts of the plant); number of flowers(florets) per panicle (expressed as a ratio of number of filled seedsover number of primary panicles); harvest index; number of plants grownper area; number and size of harvested organs per plant and per area;number of plants per growing area (density); number of harvested organsin field; total leaf area; carbon assimilation and carbon partitioning(the distribution/allocation of carbon within the plant); resistance toshade; number of harvestable organs (e.g. seeds), seeds per pod, weightper seed; and modified architecture [such as increase stalk diameter,thickness or improvement of physical properties (e.g. elasticity)].

As used herein the phrase “seed yield” refers to the number or weight ofthe seeds per plant, seeds per pod, or per growing area or to the weightof a single seed, or to the oil extracted per seed. Hence seed yield canbe affected by seed dimensions (e.g., length, width, perimeter, areaand/or volume), number of (filled) seeds and seed filling rate and byseed oil content. Hence increase seed yield per plant could affect theeconomic benefit one can obtain from the plant in a certain growing areaand/or growing time; and increase seed yield per growing area could beachieved by increasing seed yield per plant, and/or by increasing numberof plants grown on the same given area.

The term “seed” (also referred to as “grain” or “kernel”) as used hereinrefers to a small embryonic plant enclosed in a covering called the seedcoat (usually with some stored food), the product of the ripened ovuleof gymnosperm and angiosperm plants which occurs after fertilization andsome growth within the mother plant.

The phrase “oil content” as used herein refers to the amount of lipidsin a given plant organ, either the seeds (seed oil content) or thevegetative portion of the plant (vegetative oil content) and istypically expressed as percentage of dry weight (10% humidity of seeds)or wet weight (for vegetative portion).

It should be noted that oil content is affected by intrinsic oilproduction of a tissue (e.g., seed, vegetative portion), as well as themass or size of the oil-producing tissue per plant or per growth period.

In one embodiment, increase in oil content of the plant can be achievedby increasing the size/mass of a plant's tissue(s) which comprise oilper growth period. Thus, increased oil content of a plant can beachieved by increasing the yield, growth rate, biomass and vigor of theplant.

As used herein the phrase “plant biomass” refers to the amount (e.g.,measured in grams of air-dry tissue) of a tissue produced from the plantin a growing season, which could also determine or affect the plantyield or the yield per growing area. An increase in plant biomass can bein the whole plant or in parts thereof such as aboveground (harvestable)parts, vegetative biomass, roots and seeds.

As used herein the phrase “growth rate” refers to the increase in plantorgan/tissue size per time (can be measured in cm² per day).

As used herein the phrase “plant vigor” refers to the amount (measuredby weight) of tissue produced by the plant in a given time. Henceincreased vigor could determine or affect the plant yield or the yieldper growing time or growing area. In addition, early vigor (seed and/orseedling) results in improved field stand.

It should be noted that a plant yield can be determined under stress(e.g., abiotic stress, nitrogen-limiting conditions) and/or non-stress(normal) conditions.

As used herein, the phrase “non-stress conditions” refers to the growthconditions (e.g., water, temperature, light-dark cycles, humidity, saltconcentration, fertilizer concentration in soil, nutrient supply such asnitrogen, phosphorous and/or potassium), that do not significantly gobeyond the everyday climatic and other abiotic conditions that plantsmay encounter, and which allow optimal growth, metabolism, reproductionand/or viability of a plant at any stage in its life cycle (e.g., in acrop plant from seed to a mature plant and back to seed again). Personsskilled in the art are aware of normal soil conditions and climaticconditions for a given plant in a given geographic location. It shouldbe noted that while the non-stress conditions may include some mildvariations from the optimal conditions (which vary from one type/speciesof a plant to another), such variations do not cause the plant to ceasegrowing without the capacity to resume growth.

The phrase “abiotic stress” as used herein refers to any adverse effecton metabolism, growth, reproduction and/or viability of a plant.Accordingly, abiotic stress can be induced by suboptimal environmentalgrowth conditions such as, for example, salinity, water deprivation,flooding, freezing, low or high temperature, heavy metal toxicity,anaerobiosis, nutrient deficiency, atmospheric pollution or UVirradiation. The implications of abiotic stress are discussed in theBackground section.

The phrase “abiotic stress tolerance” as used herein refers to theability of a plant to endure an abiotic stress without suffering asubstantial alteration in metabolism, growth, productivity and/orviability.

As used herein the phrase “water use efficiency (WUE)” refers to thelevel of organic matter produced per unit of water consumed by theplant, i.e., the dry weight of a plant in relation to the plant's wateruse, e.g., the biomass produced per unit transpiration.

As used herein the phrase “fertilizer use efficiency” refers to themetabolic process(es) which lead to an increase in the plant's yield,biomass, vigor, and growth rate per fertilizer unit applied. Themetabolic process can be the uptake, spread, absorbent, accumulation,relocation (within the plant) and use of one or more of the minerals andorganic moieties absorbed by the plant, such as nitrogen, phosphatesand/or potassium.

As used herein the phrase “fertilizer-limiting conditions” refers togrowth conditions which include a level (e.g., concentration) of afertilizer applied which is below the level needed for normal plantmetabolism, growth, reproduction and/or viability.

As used herein the phrase “nitrogen use efficiency (NUE)” refers to themetabolic process(es) which lead to an increase in the plant's yield,biomass, vigor, and growth rate per nitrogen unit applied. The metabolicprocess can be the uptake, spread, absorbent, accumulation, relocation(within the plant) and use of nitrogen absorbed by the plant.

As used herein the phrase “nitrogen-limiting conditions” refers togrowth conditions which include a level (e.g., concentration) ofnitrogen (e.g., ammonium or nitrate) applied which is below the levelneeded for normal plant metabolism, growth, reproduction and/orviability.

Improved plant NUE and FUE is translated in the field into eitherharvesting similar quantities of yield, while implementing lessfertilizers, or increased yields gained by implementing the same levelsof fertilizers. Thus, improved NUE or FUE has a direct effect on plantyield in the field. Thus, the polynucleotides and polypeptides of someembodiments of the invention positively affect plant yield, seed yield,and plant biomass. In addition, the benefit of improved plant NUE willcertainly improve crop quality and biochemical constituents of the seedsuch as protein yield and oil yield.

It should be noted that improved ABST will confer plants with improvedvigor also under non-stress conditions, resulting in crops havingimproved biomass and/or yield e.g., elongated fibers for the cottonindustry, higher oil content.

The term “fiber” is usually inclusive of thick-walled conducting cellssuch as vessels and tracheids and to fibrillar aggregates of manyindividual fiber cells. Hence, the term “fiber” refers to (a)thick-walled conducting and non-conducting cells of the xylem; (b)fibers of extraxylary origin, including those from phloem, bark, groundtissue, and epidermis; and (c) fibers from stems, leaves, roots, seeds,and flowers or inflorescences (such as those of Sorghum vulgare used inthe manufacture of brushes and brooms).

As used herein the phrase “fiber producing plant” refers to plants thatshare the common feature of having an elongated shape and abundantcellulose in thick cell walls, typically termed as secondary walls. Suchwalls may or may not be lignified, and the protoplast of such cells mayor may be viable at maturity. Such fibers have many industrial uses, forexample in lumber and manufactured wood products, paper, textiles,sacking and boxing material, cordage, brushes and brooms, filling andstuffing, caulking, reinforcement of other materials, and manufacture ofcellulose derivatives.

Example of fiber producing plants, include, but are not limited to,agricultural crops such as cotton, silk cotton tree (Kapok, Ceibapentandra), desert willow, creosote bush, winterfat, balsa, kenaf,roselle, jute, sisal abaca, flax, corn, sugar cane, hemp, ramie, kapok,coir, bamboo, spanish moss and Agave spp.(e.g. sisal).

According to a preferred embodiment of this aspect of the presentinvention the fiber producing plant is cotton.

As used herein the phrase “fiber quality” refers to at least one fiberparameter which is agriculturally desired, or required in the fiberindustry (further described hereinbelow). Examples of such parameters,include but are not limited to, fiber length, fiber strength, fiberfitness, fiber weight per unit length, maturity ratio and uniformity.

Cotton fiber (lint) quality is typically measured according to fiberlength, strength and fineness. Accordingly, the lint quality isconsidered higher when the fiber is longer, stronger and finer.

As used herein the phrase “fiber yield” refers to the amount or quantityof fibers produced from the fiber producing plant.

As used herein the term “increasing” refers to at least about 2%, atleast about 3%, at least about 4%, at least about 5%, at least about10%, at least about 15%, at least about 20%, at least about 30%, atleast about 40%, at least about 50%, at least about 60%, at least about70%, at least about 80% or greater increase in plant yield, biomass,growth rate, vigor, oil content, fiber yield, fiber quality, water useefficiency, nitrogen use efficiency, fertilizer use efficiency and/orabiotic stress tolerance as compared to a native plant [i.e., a plantnot modified with the biomolecules (polynucleotide or polypeptides) ofthe invention, e.g., a non-transformed plant of the same species whichis grown under the same growth conditions as the transformed plant].

The phrase “expressing within the plant an exogenous polynucleotide” asused herein refers to upregulating the expression level of an exogenouspolynucleotide within the plant by introducing the exogenouspolynucleotide into a plant cell or plant and expressing by recombinantmeans, as further described herein below.

As used herein “expressing” refers to expression at the mRNA andoptionally polypeptide level.

As used herein, the phrase “exogenous polynucleotide” refers to aheterologous nucleic acid sequence which may not be naturally expressedwithin the plant or which overexpression in the plant is desired. Theexogenous polynucleotide may be introduced into the plant in a stable ortransient manner, so as to produce a ribonucleic acid (RNA) moleculeand/or a polypeptide molecule. It should be noted that the exogenouspolynucleotide may comprise a nucleic acid sequence which is identicalor partially homologous to an endogenous nucleic acid sequence of theplant.

The term “endogenous” as used herein refers to any polynucleotide orpolypeptide which is present and/or naturally expressed within a plantor a cell thereof.

According to some embodiments of the invention, the exogenouspolynucleotide comprises a nucleic acid which is at least about 80%, atleast about 81%, at least about 82%, at least about 83%, at least about84%, at least about 85%, at least about 86%, at least about 87%, atleast about 88%, at least about 89%, at least about 90%, at least about91%, at least about 92%, at least about 93%, at least about 93%, atleast about 94%, at least about 95%, at least about 96%, at least about97%, at least about 98%, at least about 99%, e.g., 100% identical to thenucleic acid sequence selected from the group consisting of SEQ ID NOs:3487, 1-239, 467-1973, 3481-3486, 3488-3674, and 3738-3739.

Identity (e.g., percent homology) can be determined using any homologycomparison software, including for example, the BlastN software of theNational Center of Biotechnology Information (NCBI) such as by usingdefault parameters.

According to some embodiments of the invention the exogenouspolynucleotide is at least about 80%, at least about 81%, at least about82%, at least about 83%, at least about 84%, at least about 85%, atleast about 86%, at least about 87%, at least about 88%, at least about89%, at least about 90%, at least about 91%, at least about 92%, atleast about 93%, at least about 93%, at least about 94%, at least about95%, at least about 96%, at least about 97%, at least about 98%, atleast about 99%, e.g., 100% identical to the polynucleotide selectedfrom the group consisting of SEQ ID NOs: 3487, 1-239, 467-1973,3481-3486, 3488-3674, and 3738-3739.

According to some embodiments of the invention the exogenouspolynucleotide consists of the nucleic acid sequence set forth in SEQ IDNO: 3487, 1-239, 467-1973, 3481-3486, 3488-3674, 3738 or 3739.

As used herein the term “polynucleotide” refers to a single or doublestranded nucleic acid sequence which is isolated and provided in theform of an RNA sequence, a complementary polynucleotide sequence (cDNA),a genomic polynucleotide sequence and/or a composite polynucleotidesequences (e.g., a combination of the above).

The term “isolated” refers to at least partially separated from thenatural environment e.g., from a plant cell.

As used herein the phrase “complementary polynucleotide sequence” refersto a sequence, which results from reverse transcription of messenger RNAusing a reverse transcriptase or any other RNA dependent DNA polymerase.Such a sequence can be subsequently amplified in vivo or in vitro usinga DNA dependent DNA polymerase.

As used herein the phrase “genomic polynucleotide sequence” refers to asequence derived (isolated) from a chromosome and thus it represents acontiguous portion of a chromosome.

As used herein the phrase “composite polynucleotide sequence” refers toa sequence, which is at least partially complementary and at leastpartially genomic. A composite sequence can include some exonalsequences required to encode the polypeptide of the present invention,as well as some intronic sequences interposing therebetween. Theintronic sequences can be of any source, including of other genes, andtypically will include conserved splicing signal sequences. Suchintronic sequences may further include cis acting expression regulatoryelements.

According to some embodiments of the invention, the exogenouspolynucleotide of the invention encodes a polypeptide which comprises anamino acid sequence at least about 80%, at least about 81%, at leastabout 82%, at least about 83%, at least about 84%, at least about 85%,at least about 86%, at least about 87%, at least about 88%, at leastabout 89%, at least about 90%, at least about 91%, at least about 92%,at least about 93%, at least about 94%, at least about 95%, at leastabout 96%, at least about 97%, at least about 98%, at least about 99%,or more say 100% homologous to the amino acid sequence selected from thegroup consisting of SEQ ID NOs: 246, 240-245, 247-465, 1974-3480, and3675-3737.

Homology (e.g., percent homology) can be determined using any homologycomparison software, including for example, the BlastP or TBLASTNsoftware of the National Center of Biotechnology Information (NCBI) suchas by using default parameters, when starting from a polypeptidesequence; or the tBLASTX algorithm (available via the NCBI) such as byusing default parameters, which compares the six-frame conceptualtranslation products of a nucleotide query sequence (both strands)against a protein sequence database.

Homologous sequences include both orthologous and paralogous sequences.The term “paralogous” relates to gene-duplications within the genome ofa species leading to paralogous genes. The term “orthologous” relates tohomologous genes in different organisms due to ancestral relationship.

One option to identify orthologues in plant species is by performing areciprocal blast search. This may be done by a first blast involvingblasting the sequence-of-interest against any sequence database, such asthe publicly available NCBI database which may be found at: HypertextTransfer Protocol://World Wide Web (dot) ncbi (dot) nlm (dot) nih (dot)gov. If orthologues in rice were sought, the sequence-of-interest wouldbe blasted against, for example, the 28,469 full-length cDNA clones fromOryza sativa Nipponbare available at NCBI. The blast results may befiltered. The full-length sequences of either the filtered results orthe non-filtered results are then blasted back (second blast) againstthe sequences of the organism from which the sequence-of-interest isderived. The results of the first and second blasts are then compared.An orthologue is identified when the sequence resulting in the highestscore (best hit) in the first blast identifies in the second blast thequery sequence (the original sequence-of-interest) as the best hit.Using the same rational a paralogue (homolog to a gene in the sameorganism) is found. In case of large sequence families, the ClustalWprogram may be used [Hypertext Transfer Protocol://World Wide Web (dot)ebi (dot) ac (dot) uk/Tools/clustalw2/index (dot) html], followed by aneighbor-joining tree (Hypertext Transfer Protocol://en (dot) wikipedia(dot) org/wiki/Neighbor-joining) which helps visualizing the clustering.

According to some embodiments of the invention, the exogenouspolynucleotide encodes a polypeptide consisting of the amino acidsequence set forth by SEQ ID NO: 246, 240-245, 247-465, 1974-3480,3675-3736 or 3737.

Nucleic acid sequences encoding the polypeptides of the presentinvention may be optimized for expression. Examples of such sequencemodifications include, but are not limited to, an altered G/C content tomore closely approach that typically found in the plant species ofinterest, and the removal of codons atypically found in the plantspecies commonly referred to as codon optimization.

The phrase “codon optimization” refers to the selection of appropriateDNA nucleotides for use within a structural gene or fragment thereofthat approaches codon usage within the plant of interest. Therefore, anoptimized gene or nucleic acid sequence refers to a gene in which thenucleotide sequence of a native or naturally occurring gene has beenmodified in order to utilize statistically-preferred orstatistically-favored codons within the plant. The nucleotide sequencetypically is examined at the DNA level and the coding region optimizedfor expression in the plant species determined using any suitableprocedure, for example as described in Sardana et al. (1996, Plant CellReports 15:677-681). In this method, the standard deviation of codonusage, a measure of codon usage bias, may be calculated by first findingthe squared proportional deviation of usage of each codon of the nativegene relative to that of highly expressed plant genes, followed by acalculation of the average squared deviation. The formula used is:1 SDCU=n=1 N[(Xn−Yn)/Yn]2/N,  Formula I

where Xn refers to the frequency of usage of codon n in highly expressedplant genes, where Yn to the frequency of usage of codon n in the geneof interest and N refers to the total number of codons in the gene ofinterest. A Table of codon usage from highly expressed genes ofdicotyledonous plants is compiled using the data of Murray et al. (1989,Nuc Acids Res. 17:477-498).

One method of optimizing the nucleic acid sequence in accordance withthe preferred codon usage for a particular plant cell type is based onthe direct use, without performing any extra statistical calculations,of codon optimization Tables such as those provided on-line at the CodonUsage Database through the NIAS (National Institute of AgrobiologicalSciences) DNA bank in Japan (Hypertext Transfer Protocol://World WideWeb (dot) kazusa (dot) or (dot) jp/codon/). The Codon Usage Databasecontains codon usage tables for a number of different species, with eachcodon usage Table having been statistically determined based on the datapresent in Genbank.

By using the above Tables to determine the most preferred or mostfavored codons for each amino acid in a particular species (for example,rice), a naturally-occurring nucleotide sequence encoding a protein ofinterest can be codon optimized for that particular plant species. Thisis effected by replacing codons that may have a low statisticalincidence in the particular species genome with corresponding codons, inregard to an amino acid, that are statistically more favored. However,one or more less-favored codons may be selected to delete existingrestriction sites, to create new ones at potentially useful junctions(5′ and 3′ ends to add signal peptide or termination cassettes, internalsites that might be used to cut and splice segments together to producea correct full-length sequence), or to eliminate nucleotide sequencesthat may negatively effect mRNA stability or expression.

The naturally-occurring encoding nucleotide sequence may already, inadvance of any modification, contain a number of codons that correspondto a statistically-favored codon in a particular plant species.Therefore, codon optimization of the native nucleotide sequence maycomprise determining which codons, within the native nucleotidesequence, are not statistically-favored with regards to a particularplant, and modifying these codons in accordance with a codon usage tableof the particular plant to produce a codon optimized derivative. Amodified nucleotide sequence may be fully or partially optimized forplant codon usage provided that the protein encoded by the modifiednucleotide sequence is produced at a level higher than the proteinencoded by the corresponding naturally occurring or native gene.Construction of synthetic genes by altering the codon usage is describedin for example PCT Patent Application 93/07278.

According to some embodiments of the invention, the exogenouspolynucleotide is a non-coding RNA.

As used herein the phrase ‘non-coding RNA” refers to an RNA moleculewhich does not encode an amino acid sequence (a polypeptide). Examplesof such non-coding RNA molecules include, but are not limited to, anantisense RNA, a pre-miRNA (precursor of a microRNA), or a precursor ofa Piwi-interacting RNA (piRNA).

Non-limiting examples of non-coding RNA polynucleotides are provided inSEQ ID NOs:37 and 43.

Thus, the invention encompasses nucleic acid sequences describedhereinabove; fragments thereof, sequences hybridizable therewith,sequences homologous thereto, sequences encoding similar polypeptideswith different codon usage, altered sequences characterized bymutations, such as deletion, insertion or substitution of one or morenucleotides, either naturally occurring or man induced, either randomlyor in a targeted fashion.

The invention provides an isolated polynucleotide comprising a nucleicacid sequence which is at least about 80%, at least about 81%, at leastabout 82%, at least about 83%, at least about 84%, at least about 85%,at least about 86%, at least about 87%, at least about 88%, at leastabout 89%, at least about 90%, at least about 91%, at least about 92%,at least about 93%, at least about 93%, at least about 94%, at leastabout 95%, at least about 96%, at least about 97%, at least about 98%,at least about 99%, e.g., 100% identical to the polynucleotide selectedfrom the group consisting of SEQ ID NOs: 3487, 1-239, 467-1973,3481-3486, 3488-3674, and 3738-3739.

According to some embodiments of the invention the nucleic acid sequenceis capable of increasing yield, biomass, growth rate, vigor, oilcontent, fiber yield, fiber quality, water use efficiency, nitrogen useefficiency, fertilizer use efficiency and/or abiotic stress tolerance ofa plant.

According to some embodiments of the invention the isolatedpolynucleotide consists of a nucleic acid sequence which is at leastabout 80%, at least about 81%, at least about 82%, at least about 83%,at least about 84%, at least about 85%, at least about 86%, at leastabout 87%, at least about 88%, at least about 89%, at least about 90%,at least about 91%, at least about 92%, at least about 93%, at leastabout 93%, at least about 94%, at least about 95%, at least about 96%,at least about 97%, at least about 98%, at least about 99%, e.g., 100%identical to the polynucleotide selected from the group consisting ofSEQ ID NOs: 3487, 1-239, 467-1973, 3481-3486, 3488-3674, and 3738-3739.

According to some embodiments of the invention the isolatedpolynucleotide comprising the nucleic acid sequence selected from thegroup consisting of SEQ ID NOs: 3487, 1-239, 467-1973, 3481-3486,3488-3674, and 3738-3739.

According to some embodiments of the invention the isolatedpolynucleotide is set forth by SEQ ID NO: 3487, 1-239, 467-1973,3481-3486, 3488-3674, 3738 or 3739.

According to some embodiments of the invention the isolatedpolynucleotide consists of a nucleic acid sequence selected from thegroup of SEQ ID NOs: 3487, 1-239, 467-1973, 3481-3486, 3488-3674, and3738-3739.

The invention provides an isolated polynucleotide comprising a nucleicacid sequence encoding a polypeptide which comprises an amino acidsequence at least about 80%, at least about 81%, at least about 82%, atleast about 83%, at least about 84%, at least about 85%, at least about86%, at least about 87%, at least about 88%, at least about 89%, atleast about 90%, at least about 91%, at least about 92%, at least about93%, at least about 93%, at least about 94%, at least about 95%, atleast about 96%, at least about 97%, at least about 98%, at least about99%, or more say 100% homologous to the amino acid sequence selectedfrom the group consisting of SEQ ID NO: 246, 240-245, 247-465,1974-3480, and 3675-3737.

According to some embodiments of the invention the amino acid sequenceis capable of increasing yield, biomass, growth rate, vigor, oilcontent, fiber yield, fiber quality, water use efficiency, nitrogen useefficiency, fertilizer use efficiency and/or abiotic stress tolerance ofa plant.

The invention provides an isolated polynucleotide comprising a nucleicacid sequence encoding a polypeptide which comprises the amino acidsequence selected from the group consisting of SEQ ID NOs: 246, 240-245,247-465, 1974-3480, and 3675-3737.

The invention provides an isolated polypeptide having an amino acidsequence at least about 80%, at least about 81%, at least about 82%, atleast about 83%, at least about 84%, at least about 85%, at least about86%, at least about 87%, at least about 88%, at least about 89%, atleast about 90%, at least about 91%, at least about 92%, at least about93%, at least about 93%, at least about 94%, at least about 95%, atleast about 96%, at least about 97%, at least about 98%, at least about99%, or more say 100% homologous to an amino acid sequence selected fromthe group consisting of SEQ ID NOs: 246, 240-245, 247-465, 1974-3480,and 3675-3737.

According to some embodiments of the invention, the isolated polypeptideis selected from the group consisting of SEQ ID NOs: 246, 240-245,247-465, 1974-3480, and 3675-3737.

The invention also encompasses fragments of the above describedpolypeptides and polypeptides having mutations, such as deletions,insertions or substitutions of one or more amino acids, either naturallyoccurring or man induced, either randomly or in a targeted fashion.

The term “plant” as used herein encompasses whole plants, ancestors andprogeny of the plants and plant parts, including seeds, shoots, stems,roots (including tubers), and plant cells, tissues and organs. The plantmay be in any form including suspension cultures, embryos, meristematicregions, callus tissue, leaves, gametophytes, sporophytes, pollen, andmicrospores. Plants that are particularly useful in the methods of theinvention include all plants which belong to the superfamilyViridiplantae, in particular monocotyledonous and dicotyledonous plantsincluding a fodder or forage legume, ornamental plant, food crop, tree,or shrub selected from the list comprising Acacia spp., Acer spp.,Actinidia spp., Aesculus spp., Agathis australis, Albizia amara,Alsophila tricolor, Andropogon spp., Arachis spp, Areca catechu, Asteliafragrans, Astragalus cicer, Baikiaea plurijuga, Betula spp., Brassicaspp., Bruguiera gymnorrhiza, Burkea africana, Butea frondosa, Cadabafarinosa, Calliandra spp, Camellia sinensis, Canna indica, Capsicumspp., Cassia spp., Centroema pubescens, Chacoomeles spp., Cinnamomumcassia, Coffea arabica, Colophospermum mopane, Coronillia varia,Cotoneaster serotina, Crataegus spp., Cucumis spp., Cupressus spp.,Cyathea dealbata, Cydonia oblonga, Cryptomeria japonica, Cymbopogonspp., Cynthea dealbata, Cydonia oblonga, Dalbergia monetaria, Davalliadivaricata, Desmodium spp., Dicksonia squarosa, Dibeteropogonamplectens, Dioclea spp, Dolichos spp., Dorycnium rectum, Echinochloapyramidalis, Ehraffia spp., Eleusine coracana, Eragrestis spp.,Erythrina spp., Eucalypfus spp., Euclea schimperi, Eulalia vi/losa,Pagopyrum spp., Feijoa sellowlana, Fragaria spp., Flemingia spp,Freycinetia banksli, Geranium thunbergii, GinAgo biloba, Glycinejavanica, Gliricidia spp, Gossypium hirsutum, Grevillea spp., Guibourtiacoleosperma, Hedysarum spp., Hemaffhia altissima, Heteropogon contoffus,Hordeum vulgare, Hyparrhenia rufa, Hypericum erectum, Hypeffheliadissolute, Indigo incamata, Iris spp., Leptarrhena pyrolifolia,Lespediza spp., Lettuca spp., Leucaena leucocephala, Loudetia simplex,Lotonus bainesli, Lotus spp., Macrotyloma axillare, Malus spp., Manihotesculenta, Medicago saliva, Metasequoia glyptostroboides, Musasapientum, Nicotianum spp., Onobrychis spp., Ornithopus spp., Oryzaspp., Peltophorum africanum, Pennisetum spp., Persea gratissima, Petuniaspp., Phaseolus spp., Phoenix canariensis, Phormium cookianum, Photiniaspp., Picea glauca, Pinus spp., Pisum sativam, Podocarpus totara,Pogonarthria fleckii, Pogonaffhria squarrosa, Populus spp., Prosopiscineraria, Pseudotsuga menziesii, Pterolobium stellatum, Pyrus communis,Quercus spp., Rhaphiolepsis umbellata, Rhopalostylis sapida, Rhusnatalensis, Ribes grossularia, Ribes spp., Robinia pseudoacacia, Rosaspp., Rubus spp., Salix spp., Schyzachyrium sanguineum, Sciadopitysvefficillata, Sequoia sempervirens, Sequoiadendron giganteum, Sorghumbicolor, Spinacia spp., Sporobolus fimbriatus, Stiburus alopecuroides,Stylosanthos humilis, Tadehagi spp., Taxodium distichum, Themedatriandra, Trifolium spp., Triticum spp., Tsuga heterophylla, Vacciniumspp., Vicia spp., Vitis vinifera, Watsonia pyramidata, Zantedeschiaaethiopica, Zea mays, amaranth, artichoke, asparagus, broccoli, Brusselssprouts, cabbage, canola, carrot, cauliflower, celery, collard greens,flax, kale, lentil, oilseed rape, okra, onion, potato, rice, soybean,straw, sugar beet, sugar cane, sunflower, tomato, squash tea, maize,wheat, barely, rye, oat, peanut, pea, lentil and alfalfa, cotton,rapeseed, canola, pepper, sunflower, tobacco, eggplant, eucalyptus, atree, an ornamental plant, a perennial grass and a forage crop.Alternatively algae and other non-Viridiplantae can be used for themethods of the present invention.

According to some embodiments of the invention, the plant used by themethod of the invention is a crop plant such as rice, maize, wheat,barley, peanut, potato, sesame, olive tree, palm oil, banana, soybean,sunflower, canola, sugarcane, alfalfa, millet, leguminosae (bean, pea),flax, lupinus, rapeseed, tobacco, poplar, cotton and sorghum.

According to some embodiments of the invention, there is provided aplant cell exogenously expressing the polynucleotide of some embodimentsof the invention, the nucleic acid construct of some embodiments of theinvention and/or the polypeptide of some embodiments of the invention.

According to some embodiments of the invention, expressing the exogenouspolynucleotide of the invention within the plant is effected bytransforming one or more cells of the plant with the exogenouspolynucleotide, followed by generating a mature plant from thetransformed cells and cultivating the mature plant under conditionssuitable for expressing the exogenous polynucleotide within the matureplant.

According to some embodiments of the invention, the transformation iseffected by introducing to the plant cell a nucleic acid construct whichincludes the exogenous polynucleotide of some embodiments of theinvention and at least one promoter capable of directing transcriptionof the exogenous polynucleotide in the plant cell. Further details ofsuitable transformation approaches are provided herein below.

According to some embodiments of the invention, there is provided anucleic acid construct comprising the isolated polynucleotide of theinvention, and a promoter for directing transcription of the nucleicacid sequence of the isolated polynucleotide in a host cell. Accordingto some embodiments of the invention, the isolated polynucleotide isoperably linked to the promoter sequence.

A coding nucleic acid sequence is “operably linked” to a regulatorysequence (e.g., promoter) if the regulatory sequence is capable ofexerting a regulatory effect on the coding sequence linked thereto.

As used herein, the term “promoter” refers to a region of DNA which liesupstream of the transcriptional initiation site of a gene to which RNApolymerase binds to initiate transcription of RNA. The promoter controlswhere (e.g., which portion of a plant) and/or when (e.g., at which stageor condition in the lifetime of an organism) the gene is expressed.

Any suitable promoter sequence can be used by the nucleic acid constructof the present invention. According to some embodiments of theinvention, the promoter is a constitutive promoter, a tissue-specific,or an abiotic stress-inducible promoter.

Suitable constitutive promoters include, for example, CaMV 35S promoter(SEQ ID NO:4196; Odell et al., Nature 313:810-812, 1985); ArabidopsisAt6669 promoter (SEQ ID NO:4195; see PCT Publication No. WO04081173A2);Arabidopsis new At6669 promoter (SEQ ID NO:4198); maize Ubi 1(Christensen et al., Plant Sol. Biol. 18:675-689, 1992); rice actin(McElroy et al., Plant Cell 2:163-171, 1990); pEMU (Last et al., Theor.Appl. Genet. 81:581-588, 1991); CaMV 19S (Nilsson et al., Physiol. Plant100:456-462, 1997); GOS2 (de Pater et al, Plant J November; 2(6):837-44,1992); ubiquitin (Christensen et al, Plant Mol. Biol. 18: 675-689,1992); Rice cyclophilin (Bucholz et al, Plant Mol Biol. 25(5):837-43,1994); Maize H3 histone (Lepetit et al, Mol. Gen. Genet. 231: 276-285,1992); Actin 2 (An et al, Plant J. 10(1);107-121, 1996) and SyntheticSuper MAS (Ni et al., The Plant Journal 7: 661-76, 1995). Otherconstitutive promoters include those in U.S. Pat. Nos. 5,659,026,5,608,149; 5,608,144; 5,604,121; 5,569,597: 5,466,785; 5,399,680;5,268,463; and 5,608,142.

Suitable tissue-specific promoters include, but not limited to,leaf-specific promoters [such as described, for example, by Yamamoto etal., Plant J. 12:255-265, 1997; Kwon et al., Plant Physiol. 105:357-67,1994; Yamamoto et al., Plant Cell Physiol. 35:773-778, 1994; Gotor etal., Plant J. 3:509-18, 1993; Orozco et al., Plant Mol. Biol.23:1129-1138, 1993; and Matsuoka et al., Proc. Natl. Acad. Sci. USA90:9586-9590, 1993], seed-preferred promoters [e.g., from seed specificgenes (Simon, et al., Plant Mol. Biol. 5. 191, 1985; Scofield, et al.,J. Biol. Chem. 262: 12202, 1987; Baszczynski, et al., Plant Mol. Biol.14: 633, 1990), Brazil Nut albumin (Pearson' et al., Plant Mol. Biol.18: 235-245, 1992), legumin (Ellis, et al. Plant Mol. Biol. 10: 203-214,1988), Glutelin (rice) (Takaiwa, et al., Mol. Gen. Genet. 208: 15-22,1986; Takaiwa, et al., FEBS Letts. 221: 43-47, 1987), Zein (Matzke etal., Plant Mol Biol, 143).323-32 1990), napA (Stalberg, et al., Planta199: 515-519, 1996), Wheat SPA (Albanietal, Plant Cell, 9: 171-184,1997), sunflower oleosin (Cummins, et al., Plant Mol. Biol. 19: 873-876,1992)], endosperm specific promoters [e.g., wheat LMW and HMW,glutenin-1 (Mol Gen Genet 216:81-90, 1989; NAR 17:461-2), wheat a, b andg gliadins (EMBO3:1409-15, 1984), Barley ltr1 promoter, barley B1, C, Dhordein (Theor Appl Gen 98:1253-62, 1999; Plant J 4:343-55, 1993; MolGen Genet 250:750-60, 1996), Barley DOF (Mena et al., The Plant Journal,116(1): 53-62, 1998), Biz2 (EP99106056.7), Synthetic promoter(Vicente-Carbajosa et al., Plant J. 13: 629-640, 1998), rice prolaminNRP33, rice -globulin Glb-1 (Wu et al., Plant Cell Physiology 39(8)885-889, 1998), rice alpha-globulin REB/OHP-1 (Nakase et al. Plant Mol.Biol. 33: 513-S22, 1997), rice ADP-glucose PP (Trans Res 6:157-68,1997), maize ESR gene family (Plant J 12:235-46, 1997), sorghumgamma-kafirin (PMB 32:1029-35, 1996); e.g., the Napin promoter (SEQ IDNO:4197)], embryo specific promoters [e.g., rice OSH1 (Sato et al.,Proc. Natl. Acad. Sci. USA, 93: 8117-8122), KNOX (Postma-Haarsma et al,Plant Mol. Biol. 39:257-71, 1999), rice oleosin (Wu et at, J. Biochem.,123:386, 1998)], and flower-specific promoters [e.g., AtPRP4, chalenesynthase (chsA) (Van der Meer, et al., Plant Mol. Biol. 15, 95-109,1990), LAT52 (Twell et al., Mol. Gen Genet. 217:240-245; 1989),apetala-3].

Suitable abiotic stress-inducible promoters include, but not limited to,salt-inducible promoters such as RD29A (Yamaguchi-Shinozalei et al.,Mol. Gen. Genet. 236:331-340, 1993); drought-inducible promoters such asmaize rab17 gene promoter (Pla et al., Plant Mol. Biol. 21:259-266,1993), maize rab28 gene promoter (Busk et al., Plant J. 11:1285-1295,1997) and maize Ivr2 gene promoter (Pelleschi et al., Plant Mol. Biol.39:373-380, 1999); heat-inducible promoters such as heat tomatohsp80-promoter from tomato (U.S. Pat. No. 5,187,267).

The nucleic acid construct of some embodiments of the invention canfurther include an appropriate selectable marker and/or an origin ofreplication. According to some embodiments of the invention, the nucleicacid construct utilized is a shuttle vector, which can propagate both inE. coli (wherein the construct comprises an appropriate selectablemarker and origin of replication) and be compatible with propagation incells. The construct according to some embodiments of the invention canbe, for example, a plasmid, a bacmid, a phagemid, a cosmid, a phage, avirus or an artificial chromosome.

The nucleic acid construct of some embodiments of the invention can beutilized to stably or transiently transform plant cells. In stabletransformation, the exogenous polynucleotide is integrated into theplant genome and as such it represents a stable and inherited trait. Intransient transformation, the exogenous polynucleotide is expressed bythe cell transformed but it is not integrated into the genome and assuch it represents a transient trait.

There are various methods of introducing foreign genes into bothmonocotyledonous and dicotyledonous plants (Potrykus, I., Annu. Rev.Plant. Physiol., Plant. Mol. Biol. (1991) 42:205-225; Shimamoto et al.,Nature (1989) 338:274-276).

The principle methods of causing stable integration of exogenous DNAinto plant genomic DNA include two main approaches:

(i) Agrobacterium-mediated gene transfer (e.g., T-DNA usingAgrobacterium tumefaciens or Agrobacterium rhizogenes); see for example,Klee et al. (1987) Annu. Rev. Plant Physiol. 38:467-486; Klee and Rogersin Cell Culture and Somatic Cell Genetics of Plants, Vol. 6, MolecularBiology of Plant Nuclear Genes, eds. Schell, J., and Vasil, L. K.,Academic Publishers, San Diego, Calif. (1989) p. 2-25; Gatenby, in PlantBiotechnology, eds. Kung, S, and Arntzen, C. J., Butterworth Publishers,Boston, Mass. (1989) p. 93-112.

(ii) Direct DNA uptake: Paszkowski et al., in Cell Culture and SomaticCell Genetics of Plants, Vol. 6, Molecular Biology of Plant NuclearGenes eds. Schell, J., and Vasil, L. K., Academic Publishers, San Diego,Calif. (1989) p. 52-68; including methods for direct uptake of DNA intoprotoplasts, Toriyama, K. et al. (1988) Bio/Technology 6:1072-1074. DNAuptake induced by brief electric shock of plant cells: Zhang et al.Plant Cell Rep. (1988) 7:379-384. Fromm et al. Nature (1986)319:791-793. DNA injection into plant cells or tissues by particlebombardment, Klein et al. Bio/Technology (1988) 6:559-563; McCabe et al.Bio/Technology (1988) 6:923-926; Sanford, Physiol. Plant. (1990)79:206-209; by the use of micropipette systems: Neuhaus et al., Theor.Appl. Genet. (1987) 75:30-36; Neuhaus and Spangenberg, Physiol. Plant.(1990) 79:213-217; glass fibers or silicon carbide whiskertransformation of cell cultures, embryos or callus tissue, U.S. Pat. No.5,464,765 or by the direct incubation of DNA with germinating pollen,DeWet et al. in Experimental Manipulation of Ovule Tissue, eds. Chapman,G. P. and Mantell, S. H. and Daniels, W. Longman, London, (1985) p.197-209; and Ohta, Proc. Natl. Acad. Sci. USA (1986) 83:715-719.

The Agrobacterium system includes the use of plasmid vectors thatcontain defined DNA segments that integrate into the plant genomic DNA.Methods of inoculation of the plant tissue vary depending upon the plantspecies and the Agrobacterium delivery system. A widely used approach isthe leaf disc procedure which can be performed with any tissue explantthat provides a good source for initiation of whole plantdifferentiation. See, e.g., Horsch et al. in Plant Molecular BiologyManual A5, Kluwer Academic Publishers, Dordrecht (1988) p. 1-9. Asupplementary approach employs the Agrobacterium delivery system incombination with vacuum infiltration. The Agrobacterium system isespecially viable in the creation of transgenic dicotyledonous plants.

There are various methods of direct DNA transfer into plant cells. Inelectroporation, the protoplasts are briefly exposed to a strongelectric field. In microinjection, the DNA is mechanically injecteddirectly into the cells using very small micropipettes. In microparticlebombardment, the DNA is adsorbed on microprojectiles such as magnesiumsulfate crystals or tungsten particles, and the microprojectiles arephysically accelerated into cells or plant tissues.

Following stable transformation plant propagation is exercised. The mostcommon method of plant propagation is by seed. Regeneration by seedpropagation, however, has the deficiency that due to heterozygositythere is a lack of uniformity in the crop, since seeds are produced byplants according to the genetic variances governed by Mendelian rules.Basically, each seed is genetically different and each will grow withits own specific traits. Therefore, it is preferred that the transformedplant be produced such that the regenerated plant has the identicaltraits and characteristics of the parent transgenic plant. For thisreason it is preferred that the transformed plant be regenerated bymicropropagation which provides a rapid, consistent reproduction of thetransformed plants.

Micropropagation is a process of growing new generation plants from asingle piece of tissue that has been excised from a selected parentplant or cultivar. This process permits the mass reproduction of plantshaving the preferred tissue expressing the fusion protein. The newgeneration plants which are produced are genetically identical to, andhave all of the characteristics of, the original plant. Micropropagationallows mass production of quality plant material in a short period oftime and offers a rapid multiplication of selected cultivars in thepreservation of the characteristics of the original transgenic ortransformed plant. The advantages of cloning plants are the speed ofplant multiplication and the quality and uniformity of plants produced.

Micropropagation is a multi-stage procedure that requires alteration ofculture medium or growth conditions between stages. Thus, themicropropagation process involves four basic stages: Stage one, initialtissue culturing; stage two, tissue culture multiplication; stage three,differentiation and plant formation; and stage four, greenhouseculturing and hardening. During stage one, initial tissue culturing, thetissue culture is established and certified contaminant-free. Duringstage two, the initial tissue culture is multiplied until a sufficientnumber of tissue samples are produced to meet production goals. Duringstage three, the tissue samples grown in stage two are divided and growninto individual plantlets. At stage four, the transformed plantlets aretransferred to a greenhouse for hardening where the plants' tolerance tolight is gradually increased so that it can be grown in the naturalenvironment.

According to some embodiments of the invention, the transgenic plantsare generated by transient transformation of leaf cells, meristematiccells or the whole plant.

Transient transformation can be effected by any of the direct DNAtransfer methods described above or by viral infection using modifiedplant viruses.

Viruses that have been shown to be useful for the transformation ofplant hosts include CaMV, Tobacco mosaic virus (TMV), brome mosaic virus(BMV) and Bean Common Mosaic Virus (BV or BCMV). Transformation ofplants using plant viruses is described in U.S. Pat. No. 4,855,237 (beangolden mosaic virus; BGV), EP-A 67,553 (TMV), Japanese PublishedApplication No. 63-14693 (TMV), EPA 194,809 (BV), EPA 278,667 (BV); andGluzman, Y. et al., Communications in Molecular Biology: Viral Vectors,Cold Spring Harbor Laboratory, New York, pp. 172-189 (1988). Pseudovirusparticles for use in expressing foreign DNA in many hosts, includingplants are described in WO 87/06261.

According to some embodiments of the invention, the virus used fortransient transformations is avirulent and thus is incapable of causingsevere symptoms such as reduced growth rate, mosaic, ring spots, leafroll, yellowing, streaking, pox formation, tumor formation and pitting.A suitable avirulent virus may be a naturally occurring avirulent virusor an artificially attenuated virus. Virus attenuation may be effectedby using methods well known in the art including, but not limited to,sub-lethal heating, chemical treatment or by directed mutagenesistechniques such as described, for example, by Kurihara and Watanabe(Molecular Plant Pathology 4:259-269, 2003), Gal-on et al. (1992),Atreya et al. (1992) and Huet et al. (1994).

Suitable virus strains can be obtained from available sources such as,for example, the American Type culture Collection (ATCC) or by isolationfrom infected plants. Isolation of viruses from infected plant tissuescan be effected by techniques well known in the art such as described,for example by Foster and Tatlor, Eds. “Plant Virology Protocols: FromVirus Isolation to Transgenic Resistance (Methods in Molecular Biology(Humana Pr), Vol 81)”, Humana Press, 1998. Briefly, tissues of aninfected plant believed to contain a high concentration of a suitablevirus, preferably young leaves and flower petals, are ground in a buffersolution (e.g., phosphate buffer solution) to produce a virus infectedsap which can be used in subsequent inoculations.

Construction of plant RNA viruses for the introduction and expression ofnon-viral exogenous polynucleotide sequences in plants is demonstratedby the above references as well as by Dawson, W. O. et al., Virology(1989) 172:285-292; Takamatsu et al. EMBO J. (1987) 6:307-311; French etal. Science (1986) 231:1294-1297; Takamatsu et al. FEBS Letters (1990)269:73-76; and U.S. Pat. No. 5,316,931.

When the virus is a DNA virus, suitable modifications can be made to thevirus itself. Alternatively, the virus can first be cloned into abacterial plasmid for ease of constructing the desired viral vector withthe foreign DNA. The virus can then be excised from the plasmid. If thevirus is a DNA virus, a bacterial origin of replication can be attachedto the viral DNA, which is then replicated by the bacteria.Transcription and translation of this DNA will produce the coat proteinwhich will encapsidate the viral DNA. If the virus is an RNA virus, thevirus is generally cloned as a cDNA and inserted into a plasmid. Theplasmid is then used to make all of the constructions. The RNA virus isthen produced by transcribing the viral sequence of the plasmid andtranslation of the viral genes to produce the coat protein(s) whichencapsidate the viral RNA.

In one embodiment, a plant viral polynucleotide is provided in which thenative coat protein coding sequence has been deleted from a viralpolynucleotide, a non-native plant viral coat protein coding sequenceand a non-native promoter, preferably the subgenomic promoter of thenon-native coat protein coding sequence, capable of expression in theplant host, packaging of the recombinant plant viral polynucleotide, andensuring a systemic infection of the host by the recombinant plant viralpolynucleotide, has been inserted. Alternatively, the coat protein genemay be inactivated by insertion of the non-native polynucleotidesequence within it, such that a protein is produced. The recombinantplant viral polynucleotide may contain one or more additional non-nativesubgenomic promoters. Each non-native subgenomic promoter is capable oftranscribing or expressing adjacent genes or polynucleotide sequences inthe plant host and incapable of recombination with each other and withnative subgenomic promoters. Non-native (foreign) polynucleotidesequences may be inserted adjacent the native plant viral subgenomicpromoter or the native and a non-native plant viral subgenomic promotersif more than one polynucleotide sequence is included. The non-nativepolynucleotide sequences are transcribed or expressed in the host plantunder control of the subgenomic promoter to produce the desiredproducts.

In a second embodiment, a recombinant plant viral polynucleotide isprovided as in the first embodiment except that the native coat proteincoding sequence is placed adjacent one of the non-native coat proteinsubgenomic promoters instead of a non-native coat protein codingsequence.

In a third embodiment, a recombinant plant viral polynucleotide isprovided in which the native coat protein gene is adjacent itssubgenomic promoter and one or more non-native subgenomic promoters havebeen inserted into the viral polynucleotide. The inserted non-nativesubgenomic promoters are capable of transcribing or expressing adjacentgenes in a plant host and are incapable of recombination with each otherand with native subgenomic promoters. Non-native polynucleotidesequences may be inserted adjacent the non-native subgenomic plant viralpromoters such that the sequences are transcribed or expressed in thehost plant under control of the subgenomic promoters to produce thedesired product.

In a fourth embodiment, a recombinant plant viral polynucleotide isprovided as in the third embodiment except that the native coat proteincoding sequence is replaced by a non-native coat protein codingsequence.

The viral vectors are encapsidated by the coat proteins encoded by therecombinant plant viral polynucleotide to produce a recombinant plantvirus. The recombinant plant viral polynucleotide or recombinant plantvirus is used to infect appropriate host plants. The recombinant plantviral polynucleotide is capable of replication in the host, systemicspread in the host, and transcription or expression of foreign gene(s)(exogenous polynucleotide) in the host to produce the desired protein.

Techniques for inoculation of viruses to plants may be found in Fosterand Taylor, eds. “Plant Virology Protocols: From Virus Isolation toTransgenic Resistance (Methods in Molecular Biology (Humana Pr), Vol81)”, Humana Press, 1998; Maramorosh and Koprowski, eds. “Methods inVirology” 7 vols, Academic Press, New York 1967-1984; Hill, S. A.“Methods in Plant Virology”, Blackwell, Oxford, 1984; Walkey, D. G. A.“Applied Plant Virology”, Wiley, New York, 1985; and Kado and Agrawa,eds. “Principles and Techniques in Plant Virology”, VanNostrand-Reinhold, New York.

In addition to the above, the polynucleotide of the present inventioncan also be introduced into a chloroplast genome thereby enablingchloroplast expression.

A technique for introducing exogenous polynucleotide sequences to thegenome of the chloroplasts is known. This technique involves thefollowing procedures. First, plant cells are chemically treated so as toreduce the number of chloroplasts per cell to about one. Then, theexogenous polynucleotide is introduced via particle bombardment into thecells with the aim of introducing at least one exogenous polynucleotidemolecule into the chloroplasts. The exogenous polynucleotide is selectedsuch that it is integratable into the chloroplast's genome viahomologous recombination which is readily effected by enzymes inherentto the chloroplast. To this end, the exogenous polynucleotide includes,in addition to a gene of interest, at least one polynucleotide stretchwhich is derived from the chloroplast's genome. In addition, theexogenous polynucleotide includes a selectable marker, which serves bysequential selection procedures to ascertain that all or substantiallyall of the copies of the chloroplast genomes following such selectionwill include the exogenous polynucleotide. Further details relating tothis technique are found in U.S. Pat. Nos. 4,945,050; and 5,693,507which are incorporated herein by reference. A polypeptide can thus beproduced by the protein expression system of the chloroplast and becomeintegrated into the chloroplast's inner membrane.

Since yield (or other parameters affecting yield such as growth rate,biomass, vigor, content of seeds, oil content and the like), fiber yieldand/or quality, water use efficiency, fertilizer use efficiency,nitrogen use efficiency and/or abiotic stress tolerance in plants caninvolve multiple genes acting additively or in synergy (see, forexample, in Quesda et al., Plant Physiol. 130:951-063, 2002), theinvention also envisages expressing a plurality of exogenouspolynucleotides in a single host plant to thereby achieve superioreffect on yield, fiber yield and/or quality, water use efficiency,fertilizer use efficiency, nitrogen use efficiency and/or abiotic stresstolerance.

Expressing a plurality of exogenous polynucleotides in a single hostplant can be effected by co-introducing multiple nucleic acidconstructs, each including a different exogenous polynucleotide, into asingle plant cell. The transformed cell can then be regenerated into amature plant using the methods described hereinabove.

Alternatively, expressing a plurality of exogenous polynucleotides in asingle host plant can be effected by co-introducing into a singleplant-cell a single nucleic-acid construct including a plurality ofdifferent exogenous polynucleotides. Such a construct can be designedwith a single promoter sequence which can transcribe a polycistronicmessenger RNA including all the different exogenous polynucleotidesequences. To enable co-translation of the different polypeptidesencoded by the polycistronic messenger RNA, the polynucleotide sequencescan be inter-linked via an internal ribosome entry site (IRES) sequencewhich facilitates translation of polynucleotide sequences positioneddownstream of the IRES sequence. In this case, a transcribedpolycistronic RNA molecule encoding the different polypeptides describedabove will be translated from both the capped 5′ end and the twointernal IRES sequences of the polycistronic RNA molecule to therebyproduce in the cell all different polypeptides. Alternatively, theconstruct can include several promoter sequences each linked to adifferent exogenous polynucleotide sequence.

The plant cell transformed with the construct including a plurality ofdifferent exogenous polynucleotides can be regenerated into a matureplant, using the methods described hereinabove.

Alternatively, expressing a plurality of exogenous polynucleotides canbe effected by introducing different nucleic acid constructs, includingdifferent exogenous polynucleotides, into a plurality of plants. Theregenerated transformed plants can then be cross-bred and resultantprogeny selected for superior yield (e.g., growth rate, biomass, vigor,oil content), fiber yield and/or quality, water use efficiency,fertilizer use efficiency, nitrogen use efficiency and/or abiotic stresstolerance traits, using conventional plant breeding techniques.

According to some embodiments of the invention, the plant expressing theexogenous polynucleotide(s) is grown under non-stress or normalconditions (e.g., biotic conditions and/or conditions with sufficientwater, nutrients such as nitrogen and fertilizer). Such conditions,which depend on the plant being grown, are known to those skilled in theart of agriculture, and are further, described hereinbelow.

According to some embodiments of the invention, the method furthercomprising growing the plant expressing the exogenous polynucleotideunder the abiotic stress.

Non-limiting examples of abiotic stress conditions include, salinity,drought, water deprivation, excess of water (e.g., flood, waterlogging),etiolation, low temperature, high temperature, heavy metal toxicity,anaerobiosis, nutrient deficiency, nutrient excess, atmosphericpollution and UV irradiation.

Thus, the invention encompasses plants exogenously expressing thepolynucleotide(s), the nucleic acid constructs and/or polypeptide(s) ofthe invention. Once expressed within the plant cell or the entire plant,the level of the polypeptide encoded by the exogenous polynucleotide canbe determined by methods well known in the art such as, activity assays,Western blots using antibodies capable of specifically binding thepolypeptide, Enzyme-Linked Immuno Sorbent Assay (ELISA),radio-immuno-assays (RIA), immunohistochemistry, immunocytochemistry,immunofluorescence and the like.

Methods of determining the level in the plant of the RNA transcribedfrom the exogenous polynucleotide are well known in the art and include,for example, Northern blot analysis, reverse transcription polymerasechain reaction (RT-PCR) analysis (including quantitative,semi-quantitative or real-time RT-PCR) and RNA-in situ hybridization.

The sequence information and annotations uncovered by the presentteachings can be harnessed in favor of classical breeding. Thus,sub-sequence data of those polynucleotides described above, can be usedas markers for marker assisted selection (MAS), in which a marker isused for indirect selection of a genetic determinant or determinants ofa trait of interest (e.g., biomass, growth rate, oil content, fiberyield and/or quality, yield, abiotic stress tolerance, water useefficiency, nitrogen use efficiency and/or fertilizer use efficiency).Nucleic acid data of the present teachings (DNA or RNA sequence) maycontain or be linked to polymorphic sites or genetic markers on thegenome such as restriction fragment length polymorphism (RFLP),microsatellites and single nucleotide polymorphism (SNP), DNAfingerprinting (DFP), amplified fragment length polymorphism (AFLP),expression level polymorphism, polymorphism of the encoded polypeptideand any other polymorphism at the DNA or RNA sequence.

Examples of marker assisted selections include, but are not limited to,selection for a morphological trait (e.g., a gene that affects form,coloration, male sterility or resistance such as the presence or absenceof awn, leaf sheath coloration, height, grain color, aroma of rice);selection for a biochemical trait (e.g., a gene that encodes a proteinthat can be extracted and observed; for example, isozymes and storageproteins); selection for a biological trait (e.g., pathogen races orinsect biotypes based on host pathogen or host parasite interaction canbe used as a marker since the genetic constitution of an organism canaffect its susceptibility to pathogens or parasites).

The polynucleotides and polypeptides described hereinabove can be usedin a wide range of economical plants, in a safe and cost effectivemanner.

Plant lines exogenously expressing the polynucleotide or the polypeptideof the invention can be screened to identify those that show thegreatest increase of the desired plant trait.

The effect of the transgene (the exogenous polynucleotide encoding thepolypeptide) on abiotic stress tolerance can be determined using knownmethods such as detailed below and in the Examples section whichfollows.

Plant's growth rate, biomass, yield and/or vigor—Plant vigor can becalculated by the increase in growth parameters such as leaf area, fiberlength, rosette diameter, plant fresh weight and the like per time.

The growth rate can be measured using digital analysis of growingplants. For example, images of plants growing in greenhouse on plotbasis can be captured every 3 days and the rosette area can becalculated by digital analysis. Rosette area growth is calculated usingthe difference of rosette area between days of sampling divided by thedifference in days between samples.

Evaluation of growth rate can be also done by measuring plant biomassproduced, rosette area, leaf size or root length per time (can bemeasured in cm² per day of leaf area).

Relative growth area can be calculated using Formula II.Relative growth rate area=Regression coefficient of area along timecourse  Formula II

Thus, the relative growth area rate is in units of 1/day and lengthgrowth rate is in units of 1/day.

Seed yield—Evaluation of the seed yield per plant can be done bymeasuring the amount (weight or size) or quantity (i.e., number) of dryseeds produced and harvested from 8-16 plants and divided by the numberof plants.

For example, the total seeds from 8-16 plants can be collected, weightedusing e.g., an analytical balance and the total weight can be divided bythe number of plants. Seed yield per growing area can be calculated inthe same manner while taking into account the growing area given to asingle plant. Increase seed yield per growing area could be achieved byincreasing seed yield per plant, and/or by increasing number of plantscapable of growing in a given area.

Seed yield can be expressed as thousand kernel weight (1000-weight),which is extrapolated from the number of filled seeds counted and theirtotal weight. Hence, an increased 1000-weight may result from anincreased seed size and/or seed weight (e.g., increase in embryo sizeand/or endosperm size). For example, the weight of 1000 seeds can bedetermined as follows: seeds are scattered on a glass tray and a pictureis taken. Each sample is weighted and then using the digital analysis,the number of seeds in each sample is calculated.

The 1000 seeds weight can be calculated using formula III:1000 Seed Weight=number of seed in sample/sample weight×1000  FormulaIII

The Harvest Index can be calculated using Formula IVHarvest Index=Average seed yield per plant/Average dry weight  FormulaIV

Since the transgenic plants of the invention have increased yield, it islikely that these plants exhibit an increased growth rate (during atleast part of their life cycle), relative to the growth rate ofcorresponding wild type plants at a corresponding stage in their lifecycle. The increased growth rate may be specific to one or more parts ofa plant (including seeds), or may be throughout substantially the wholeplant. A plant having an increased growth rate may also exhibit earlyflowering. Increased growth rate during the early stages in the lifecycle of a plant may reflect enhanced vigor. The increase in growth ratemay alter the harvest cycle (early maturing) of a plant allowing plantsto be sown later and/or harvested sooner than would otherwise bepossible. If the growth rate is sufficiently increased, it may allow forthe sowing of further seeds of the same plant species (for examplesowing and harvesting of rice plants followed by sowing and harvestingof further rice plants all within one conventional growing period).Similarly, if the growth rate is sufficiently increased, it may allowfor the sowing of further seeds of different plants species (for examplethe sowing and harvesting of rice plants followed by, for example, thesowing and optional harvesting of soybean, potato or any other suitableplant). Harvesting additional times from the same rootstock in the caseof some plants may also be possible. Altering the harvest cycle of aplant may lead to an increase in annual biomass production per area (dueto an increase in the number of times (say in a year) that anyparticular plant may be grown and harvested). An increase in growth ratemay also allow for the cultivation of transgenic plants in a widergeographical area than their wild-type counterparts, since theterritorial limitations for growing a crop are often determined byadverse environmental conditions either at the time of planting (earlyseason) or at the time of harvesting (late season). Such adverseconditions may be avoided if the harvest cycle is shortened. The growthrate may be determined by deriving various parameters from growthcurves, such parameters may be: T-Mid (the time taken for plants toreach 50% of their maximal size) and T-90 (time taken for plants toreach 90% of their maximal size).

According to some embodiments of the invention, increased yield of cornmay be manifested as one or more of the following: increase in thenumber of plants per growing area, increase in the number of ears perplant, increase in the number of rows per ear, number of kernels per earrow, kernel weight, thousand kernel weight (1000-weight), earlength/diameter, increase oil content per kernel and increase starchcontent per kernel.

As mentioned, the increase of plant yield can be determined by variousparameters. For example, increased yield of rice may be manifested by anincrease in one or more of the following: number of plants per growingarea, number of panicles per plant, number of spikelets per panicle,number of flowers per panicle, increase in the seed filling rate,increase in thousand kernel weight (1000-weight), increase oil contentper seed, increase starch content per seed, among others. An increase inyield may also result in modified architecture, or may occur because ofmodified architecture.

Similarly, increased yield of soybean may be manifested by an increasein one or more of the following: number of plants per growing area,number of pods per plant, number of seeds per pod, increase in the seedfilling rate, increase in thousand seed weight (1000-weight), reduce podshattering, increase oil content per seed, increase protein content perseed, among others. An increase in yield may also result in modifiedarchitecture, or may occur because of modified architecture.

Increased yield of canola may be manifested by an increase in one ormore of the following: number of plants per growing area, number of podsper plant, number of seeds per pod, increase in the seed filling rate,increase in thousand seed weight (1000-weight), reduce pod shattering,increase oil content per seed, among others. An increase in yield mayalso result in modified architecture, or may occur because of modifiedarchitecture.

Increased yield of cotton may be manifested by an increase in one ormore of the following: number of plants per growing area, number ofbolls per plant, number of seeds per boll, increase in the seed fillingrate, increase in thousand seed weight (1000-weight), increase oilcontent per seed, improve fiber length, fiber strength, among others. Anincrease in yield may also result in modified architecture, or may occurbecause of modified architecture.

Oil content—The oil content of a plant can be determined by extractionof the oil from the seed or the vegetative portion of the plant.Briefly, lipids (oil) can be removed from the plant (e.g., seed) bygrinding the plant tissue in the presence of specific solvents (e.g.,hexane or petroleum ether) and extracting the oil in a continuousextractor. Indirect oil content analysis can be carried out usingvarious known methods such as Nuclear Magnetic Resonance (NMR)Spectroscopy, which measures the resonance energy absorbed by hydrogenatoms in the liquid state of the sample [See for example, Conway T F.and Earle F R., 1963, Journal of the American Oil Chemists' Society;Springer Berlin/Heidelberg, ISSN: 0003-021X (Print) 1558-9331 (Online)];the Near Infrared (NI) Spectroscopy, which utilizes the absorption ofnear infrared energy (1100-2500 nm) by the sample; and a methoddescribed in WO/2001/023884, which is based on extracting oil a solvent,evaporating the solvent in a gas stream which forms oil particles, anddirecting a light into the gas stream and oil particles which forms adetectable reflected light.

Fiber length can be measured using fibrograph. The fibrograph system wasused to compute length in terms of “Upper Half Mean” length. The upperhalf mean (UHM) is the average length of longer half of the fiberdistribution. The fibrograph measures length in span lengths at a givenpercentage point (Hypertext Transfer Protocol://World Wide Web (dot)cottoninc (dot) com/ClassificationofCotton/?Pg=4#Length).

Abiotic stress tolerance—Transformed (i.e., expressing the transgene)and non-transformed (wild type) plants are exposed to an abiotic stresscondition, such as water deprivation, suboptimal temperature (lowtemperature, high temperature), nutrient deficiency, nutrient excess, asalt stress condition, osmotic stress, high or low light conditions,heavy metal toxicity, anaerobiosis, atmospheric pollution and UVirradiation.

Salinity tolerance assay—Transgenic plants with tolerance to high saltconcentrations are expected to exhibit better germination, seedlingvigor or growth in high salt. Salt stress can be effected in many wayssuch as, for example, by irrigating the plants with a hyperosmoticsolution, by cultivating the plants hydroponically in a hyperosmoticgrowth solution (e.g., Hoagland solution with added salt), or byculturing the plants in a hyperosmotic growth medium [e.g., 50%Murashige-Skoog medium (MS medium) with added salt]. Since differentplants vary considerably in their tolerance to salinity, the saltconcentration in the irrigation water, growth solution, or growth mediumcan be adjusted according to the specific characteristics of thespecific plant cultivar or variety, so as to inflict a mild or moderateeffect on the physiology and/or morphology of the plants (for guidelinesas to appropriate concentration see, Bernstein and Kafkafi, Root GrowthUnder Salinity Stress In: Plant Roots, The Hidden Half 3rd ed. Waisel Y,Eshel A and Kafkafi U. (editors) Marcel Dekker Inc., New York, 2002, andreference therein).

For example, a salinity tolerance test can be performed by irrigatingplants at different developmental stages with increasing concentrationsof sodium chloride (for example 50 mM, 100 mM, 200 mM, 400 mM NaCl)applied from the bottom and from above to ensure even dispersal of salt.Following exposure to the stress condition the plants are frequentlymonitored until substantial physiological and/or morphological effectsappear in wild type plants. Thus, the external phenotypic appearance,degree of chlorosis and overall success to reach maturity and yieldprogeny are compared between control and transgenic plants. Quantitativeparameters of tolerance measured include, but are not limited to, theaverage wet and dry weight, growth rate, leaf size, leaf coverage(overall leaf area), the weight of the seeds yielded, the average seedsize and the number of seeds produced per plant. Transformed plants notexhibiting substantial physiological and/or morphological effects, orexhibiting higher biomass than wild-type plants, are identified asabiotic stress tolerant plants.

Osmotic tolerance test—Osmotic stress assays (including sodium chlorideand PEG assays) are conducted to determine if an osmotic stressphenotype was sodium chloride-specific or if it was a general osmoticstress related phenotype. Plants which are tolerant to osmotic stressmay have more tolerance to drought and/or freezing. For salt and osmoticstress experiments, the medium is supplemented for example with 50 mM,100 mM, 200 mM NaCl or 15%, 20% or 25% PEG.

Drought tolerance assay—Soil-based drought screens are performed withplants overexpressing the polynucleotides detailed above. Seeds fromcontrol Arabidopsis plants, or other transgenic plants overexpressingthe polypeptide of the invention are germinated and transferred to pots.Drought stress is obtained after irrigation is ceased. Transgenic andcontrol plants are compared to each other when the majority of thecontrol plants develop severe wilting. Plants are re-watered afterobtaining a significant fraction of the control plants displaying asevere wilting. Plants are ranked comparing to controls for each of twocriteria: tolerance to the drought conditions and recovery (survival)following re-watering.

Quantitative parameters of tolerance measured include, but are notlimited to, the average wet and dry weight, growth rate, leaf size, leafcoverage (overall leaf area), the weight of the seeds yielded, theaverage seed size and the number of seeds produced per plant.Transformed plants not exhibiting substantial physiological and/ormorphological effects, or exhibiting higher biomass than wild-typeplants, are identified as drought stress tolerant plants

Cold stress tolerance—One way to analyze cold stress is as follows.Mature (25 day old) plants are transferred to 4° C. chambers for 1 or 2weeks, with constitutive light. Later on plants are moved back togreenhouse. Two weeks later damages from chilling period, resulting ingrowth retardation and other phenotypes, are compared between controland transgenic plants, by measuring plant weight (wet and dry), and bycomparing growth rates measured as time to flowering, plant size, yield,and the like.

Heat stress tolerance—One way to measure heat stress tolerance is byexposing the plants to temperatures above 34° C. for a certain period.Plant tolerance is examined after transferring the plants back to 22° C.for recovery and evaluation after 5 days relative to internal controls(non-transgenic plants) or plants not exposed to neither cold or heatstress.

Germination tests—Germination tests compare the percentage of seeds fromtransgenic plants that could complete the germination process to thepercentage of seeds from control plants that are treated in the samemanner. Normal conditions are considered for example, incubations at 22°C. under 22-hour light 2-hour dark daily cycles. Evaluation ofgermination and seedling vigor is conducted between 4 and 14 days afterplanting. The basal media is 50% MS medium (Murashige and Skoog, 1962Plant Physiology 15, 473-497).

Germination is checked also at unfavorable conditions such as cold(incubating at temperatures lower than 10° C. instead of 22° C.) orusing seed inhibition solutions that contain high concentrations of anosmolyte such as sorbitol (at concentrations of 50 mM, 100 mM, 200 mM,300 mM, 500 mM, and up to 1000 mM) or applying increasing concentrationsof salt (of 50 mM, 100 mM, 200 mM, 300 mM, 500 mM NaCl).

Water use efficiency (WUE)—can be determined as the biomass produced perunit transpiration. To analyze WUE, leaf relative water content can bemeasured in control and transgenic plants. Fresh weight (FW) isimmediately recorded; then leaves are soaked for 8 hours in distilledwater at room temperature in the dark, and the turgid weight (TW) isrecorded. Total dry weight (DW) is recorded after drying the leaves at60° C. to a constant weight. Relative water content (RWC) is calculatedaccording to the following Formula V:RWC=(FW−DW/TW−DW)×100  Formula V

Plants that maintain high relative water content (RWC) compared tocontrol lines are considered more tolerant to drought than thoseexhibiting reduced relative water content. A non limiting example inArabidopsis is when water uptake by roots matches water loss bytranspiration from leaves. Under these circumstances the plant isdetermined to be under equilibrium and the RWC is about 0.9. When theRWC of transgenic plants decreases significantly less as compared towild type plants, the transgenic plants are considered more tolerant todrought [Gaxiola et al. PNAS Sep. 25, 2001 vol. 98 no. 20 11444-11449].

Fertilizer use efficiency—To analyze whether the transgenic plants aremore responsive to fertilizers, plants are grown in agar plates or potscontaining growth media with a limited amount of fertilizer (e.g.,nitrogen, phosphate, potassium), essentially as described in Yanagisawaet al (Proc Natl Acad Sci USA. 2004; 101:7833-8). The plants areanalyzed for their overall size, time to flowering, yield, proteincontent of shoot, grain and/or seed production. The parameters checkedare the overall size of the mature plant, its wet and dry weight, theweight of the seeds yielded, the average seed size and the number ofseeds produced per plant. Other parameters that may be tested are: thechlorophyll content of leaves (as nitrogen plant status and the degreeof leaf greenness is highly correlated), amino acid and the totalprotein content of the seeds or other plant parts such as leaves orshoots, oil content, etc. In this way, nitrogen use efficiency (NUE),phosphate use efficiency (PUE) and potassium use efficiency (KUE) areassessed, checking the ability of the transgenic plants which expressthe exogenous polynucleotide of the invention to thrive under nutrientrestraining conditions. For example, to analyze whether the transgenicArabidopsis plants are more responsive to phosphate, plants are grown in250 mM (phosphate deficient conditions) or 1 mM (optimal phosphateconcentration). To test the potassium use efficiency, Arabidopsis plantswhich express the exogenous polynucleotide of the invention are grown in0.03 mM potassium (potassium deficient conditions) or 3 mM potassium(optimal potassium concentration) essentially as described by Watson etal. Plant Physiol. (1996) 111: 1077-1083.

Nitrogen determination—The procedure for N (nitrogen) concentrationdetermination in the structural parts of the plants involves thepotassium persulfate digestion method to convert organic N to NO₃ ⁻(Purcell and King 1996 Argon. J. 88:111-113, the modified Cd⁻ mediatedreduction of NO₃ ⁻ to NO₂ ⁻ (Vodovotz 1996 Biotechniques 20:390-394) andthe measurement of nitrite by the Griess assay (Vodovotz 1996, supra).The absorbance values are measured at 550 nm against a standard curve ofNaNO₂. The procedure is described in details in Samonte et al. 2006Agron. J. 98:168-176.

Nitrogen use efficiency—To analyze whether the transgenic Arabidopsisplants are more responsive to nitrogen plant are grown in 0.75-1.5 mM(nitrogen deficient conditions) or 6-10 mM (optimal nitrogenconcentration). Plants are allowed to grow for additional 20 days oruntil seed production. The plants are then analyzed for their overallsize, time to flowering, yield, protein content of shoot and/orgrain/seed production. The parameters checked can be the overall size ofthe plant, wet and dry weight, the weight of the seeds yielded, theaverage seed size and the number of seeds produced per plant. Otherparameters that may be tested are: the chlorophyll content of leaves (asnitrogen plant status and the degree of leaf greenness is highlycorrelated), amino acid and the total protein content of the seeds orother plant parts such as leaves or shoots and oil content. Transformedplants not exhibiting substantial physiological and/or morphologicaleffects, or exhibiting higher measured parameters levels than wild-typeplants, are identified as nitrogen use efficient plants.

Nitrogen use efficiency assay using plantlets—The assay is doneaccording to Yanagisawa-S. et al. with minor modifications (“Metabolicengineering with Dof1 transcription factor in plants: Improved nitrogenassimilation and growth under low-nitrogen conditions” Proc. Natl. Acad.Sci. USA 101, 7833-7838). Briefly, transgenic plants which are grown for7-10 days in 0.5×MS [Murashige-Skoog] supplemented with a selectionagent are transferred to two nitrogen-limiting conditions: MS media inwhich the combined nitrogen concentration (NH₄NO₃ and KNO₃) was 0.2 mMor 0.05 mM. Plants are allowed to grow for additional 30-40 days andthen photographed, individually removed from the Agar (the shoot withoutthe roots) and immediately weighed (fresh weight) for later statisticalanalysis. Constructs for which only T1 seeds are available are sown onselective media and at least 25 seedlings (each one representing anindependent transformation event) are carefully transferred to thenitrogen-limiting media. For constructs for which T2 seeds areavailable, different transformation events are analyzed. Usually, 25randomly selected plants from each event are transferred to thenitrogen-limiting media allowed to grow for 3-4 additional weeks andindividually weighed at the end of that period. Transgenic plants arecompared to control plants grown in parallel under the same conditions.Mock-transgenic plants expressing the uidA reporter gene (GUS) under thesame promoter are used as control.

Grain protein concentration—Grain protein content (g grain protein m⁻²)is estimated as the product of the mass of grain N (g grain N m⁻²)multiplied by the N/protein conversion ratio of k-5.13 (Mosse 1990,supra). The grain protein concentration is estimated as the ratio ofgrain protein content per unit mass of the grain (g grain protein kg⁻¹grain).

Thus, the present invention is of high agricultural value for promotingthe yield, biomass, growth rate, vigor, water use efficiency, fertilizeruse efficiency, nitrogen use efficiency and abiotic stress tolerance ofcommercially desired crops (e.g., biomass of vegetative organ such aspoplar wood, or reproductive organ such as number of seeds or seedbiomass).

As used herein the term “about” refers to ±10%.

The terms “comprises”, “comprising”, “includes”, “including”, “having”and their conjugates mean “including but not limited to”.

The term “consisting of” means “including and limited to”.

The term “consisting essentially of” means that the composition, methodor structure may include additional ingredients, steps and/or parts, butonly if the additional ingredients, steps and/or parts do not materiallyalter the basic and novel characteristics of the claimed composition,method or structure.

As used herein, the singular form “a”, “an” and “the” include pluralreferences unless the context clearly dictates otherwise. For example,the term “a compound” or “at least one compound” may include a pluralityof compounds, including mixtures thereof.

Throughout this application, various embodiments of this invention maybe presented in a range format. It should be understood that thedescription in range format is merely for convenience and brevity andshould not be construed as an inflexible limitation on the scope of theinvention. Accordingly, the description of a range should be consideredto have specifically disclosed all the possible subranges as well asindividual numerical values within that range. For example, descriptionof a range such as from 1 to 6 should be considered to have specificallydisclosed subranges such as from 1 to 3, from 1 to 4, from 1 to 5, from2 to 4, from 2 to 6, from 3 to 6 etc., as well as individual numberswithin that range, for example, 1, 2, 3, 4, 5, and 6. This appliesregardless of the breadth of the range.

Whenever a numerical range is indicated herein, it is meant to includeany cited numeral (fractional or integral) within the indicated range.The phrases “ranging/ranges between” a first indicate number and asecond indicate number and “ranging/ranges from” a first indicate number“to” a second indicate number are used herein interchangeably and aremeant to include the first and second indicated numbers and all thefractional and integral numerals therebetween.

As used herein the term “method” refers to manners, means, techniquesand procedures for accomplishing a given task including, but not limitedto, those manners, means, techniques and procedures either known to, orreadily developed from known manners, means, techniques and proceduresby practitioners of the chemical, pharmacological, biological,biochemical and medical arts.

It is appreciated that certain features of the invention, which are, forclarity, described in the context of separate embodiments, may also beprovided in combination in a single embodiment. Conversely, variousfeatures of the invention, which are, for brevity, described in thecontext of a single embodiment, may also be provided separately or inany suitable subcombination or as suitable in any other describedembodiment of the invention. Certain features described in the contextof various embodiments are not to be considered essential features ofthose embodiments, unless the embodiment is inoperative without thoseelements.

Various embodiments and aspects of the present invention as delineatedhereinabove and as claimed in the claims section below find experimentalsupport in the following examples.

EXAMPLES

Reference is now made to the following examples, which together with theabove descriptions illustrate some embodiments of the invention in a nonlimiting fashion.

Generally, the nomenclature used herein and the laboratory proceduresutilized in the present invention include molecular, biochemical,microbiological and recombinant DNA techniques. Such techniques arethoroughly explained in the literature. See, for example, “MolecularCloning: A laboratory Manual” Sambrook et al., (1989); “CurrentProtocols in Molecular Biology” Volumes I-III Ausubel, R. M., ed.(1994); Ausubel et al., “Current Protocols in Molecular Biology”, JohnWiley and Sons, Baltimore, Md. (1989); Perbal, “A Practical Guide toMolecular Cloning”, John Wiley & Sons, New York (1988); Watson et al.,“Recombinant DNA”, Scientific American Books, New York; Birren et al.(eds) “Genome Analysis: A Laboratory Manual Series”, Vols. 1-4, ColdSpring Harbor Laboratory Press, New York (1998); methodologies as setforth in U.S. Pat. Nos. 4,666,828; 4,683,202; 4,801,531; 5,192,659 and5,272,057; “Cell Biology: A Laboratory Handbook”, Volumes I-III Cellis,J. E., ed. (1994); “Current Protocols in Immunology” Volumes I-IIIColigan J. E., ed. (1994); Stites et al. (eds), “Basic and ClinicalImmunology” (8th Edition), Appleton & Lange, Norwalk, Conn. (1994);Mishell and Shiigi (eds), “Selected Methods in Cellular Immunology”, W.H. Freeman and Co., New York (1980); available immunoassays areextensively described in the patent and scientific literature, see, forexample, U.S. Pat. Nos. 3,791,932; 3,839,153; 3,850,752; 3,850,578;3,853,987; 3,867,517; 3,879,262; 3,901,654; 3,935,074; 3,984,533;3,996,345; 4,034,074; 4,098,876; 4,879,219; 5,011,771 and 5,281,521;“Oligonucleotide Synthesis” Gait, M. J., ed. (1984); “Nucleic AcidHybridization” Hames, B. D., and Higgins S. J., eds. (1985);“Transcription and Translation” Hames, B. D., and Higgins S. J., Eds.(1984); “Animal Cell Culture” Freshney, R. I., ed. (1986); “ImmobilizedCells and Enzymes” IRL Press, (1986); “A Practical Guide to MolecularCloning” Perbal, B., (1984) and “Methods in Enzymology” Vol. 1-317,Academic Press; “PCR Protocols: A Guide To Methods And Applications”,Academic Press, San Diego, Calif. (1990); Marshak et al., “Strategiesfor Protein Purification and Characterization—A Laboratory CourseManual” CSHL Press (1996); all of which are incorporated by reference asif fully set forth herein. Other general references are providedthroughout this document. The procedures therein are believed to be wellknown in the art and are provided for the convenience of the reader. Allthe information contained therein is incorporated herein by reference.

Example 1 Identify Genes which Improve Yield and Agronomical ImportantTraits in Plants

The present inventors have identified polynucleotides which expressionthereof in plants can increase yield, fiber yield, fiber quality, growthrate, vigor, biomass, growth rate, oil content, abiotic stress tolerance(ABST), nitrogen use efficiency (NUE), water use efficiency (WUE) andfertilizer use efficiency (FUE) of a plant, as follows.

All nucleotide sequence datasets used here were originated from publiclyavailable databases or from performing sequencing using the Solexatechnology (e.g. Barley and Sorghum). Sequence data from 100 differentplant species was introduced into a single, comprehensive database.Other information on gene expression, protein annotation, enzymes andpathways were also incorporated. Major databases used include:

Genomes

-   -   Arabidopsis genome [TAIR genome version 6 (Hypertext Transfer        Protocol://World Wide Web (dot) arabidopsis (dot) org/)]    -   Rice genome [IRGSP build 4.0 (Hypertext Transfer Protocol://rgp        (dot) dna (dot) affrc (dot) go (dot) jp/IRGSP/)].    -   Poplar [Populus trichocarpa release 1.1 from JGI (assembly        release v1.0) (Hypertext Transfer Protocol://World Wide Web        (dot) genome (dot) jgi-psf (dot) org/)]    -   Brachypodium [JGI 4× assembly, Hypertext Transfer        Protocol://World Wide Web (dot) brachpodium (dot) org)]    -   Soybean [DOE-JGI SCP, version Glyma0 (Hypertext Transfer        Protocol://World Wide Web (dot) phytozome (dot) net/)]    -   Grape [French-Italian Public Consortium for Grapevine Genome        Characterization grapevine genome (Hypertext Transfer        Protocol://World Wide Web (dot) genoscope (dot) cns (dot) fr/)]    -   Castobean [TIGR/J Craig Venter Institute 4× assembly [(Hypertext        Transfer Protocol://msc (dot) jcvi (dot) org/r communis]    -   Sorghum [DOE-JGI SCP, version Sbi1 [Hypertext Transfer        Protocol://World Wide Web (dot) phytozome (dot) net/)].    -   Partially assembled genome of Maize [Hypertext Transfer        Protocol://maizesequence (dot) org/]

Expressed EST and mRNA Sequences were Extracted from the FollowingDatabases:

-   -   GeneBank versions 154, 157, 160, 161, 164, 165, 166 and 168        (Hypertext Transfer Protocol://World Wide Web (dot) ncbi (dot)        nlm (dot) nih (dot) gov/dbEST/)    -   RefSeq (Hypertext Transfer Protocol://World Wide Web (dot) ncbi        (dot) nlm (dot) nih (dot) gov/RefSeq/).    -   TAIR (Hypertext Transfer Protocol://World Wide Web (dot)        arabidopsis (dot) org/).

Protein and Pathway Databases

-   -   Uniprot [Hypertext Transfer Protocol://World Wide Web (dot)        uniprot (dot) org/].    -   AraCyc [Hypertext Transfer Protocol://World Wide Web (dot)        arabidopsis (dot) org/biocyc/index (dot) jsp].    -   ENZYME [Hypertext Transfer Protocol://expasy (dot) org/enzyme/].

Microarray Datasets were Downloaded from:

-   -   GEO (Hypertext Transfer Protocol://World Wide        Web.ncbi.nlm.nih.gov/geo/)    -   TAIR (Hypertext Transfer Protocol://World Wide        Web.arabidopsis.org/).    -   Proprietary microarray data (WO2008/122980).

QTL and SNPs Information

-   -   Gramene [Hypertext Transfer Protocol://World Wide Web (dot)        gramene (dot) org/qt1/].    -   Panzea [Hypertext Transfer Protocol://World Wide Web (dot)        panzea (dot) org/index (dot) html].

Database Assembly—was performed to build a wide, rich, reliableannotated and easy to analyze database comprised of publicly availablegenomic mRNA, ESTs DNA sequences, data from various crops as well asgene expression, protein annotation and pathway data QTLs, and otherrelevant information.

Database assembly is comprised of a toolbox of gene refining,structuring, annotation and analysis tools enabling to construct atailored database for each gene discovery project. Gene refining andstructuring tools enable to reliably detect splice variants andantisense transcripts, generating understanding of various potentialphenotypic outcomes of a single gene. The capabilities of the “LEADS”platform of Compugen LTD for analyzing human genome have been confirmedand accepted by the scientific community [see e.g., “WidespreadAntisense Transcription”, Yelin, et al. (2003) Nature Biotechnology 21,379-85; “Splicing of Alu Sequences”, Lev-Maor, et al. (2003) Science 300(5623), 1288-91; “Computational analysis of alternative splicing usingEST tissue information”, Xie H et al. Genomics 2002], and have beenproven most efficient in plant genomics as well.

EST clustering and gene assembly—For gene clustering and assembly oforganisms with available genome sequence data (arabidopsis, rice,castorbean, grape, brachypodium, poplar, soybean, sorghum) the genomicLEADS version (GANG) was employed. This tool allows most accurateclustering of ESTs and mRNA sequences on genome, and predicts genestructure as well as alternative splicing events and anti-sensetranscription.

For organisms with no available full genome sequence data, “expressedLEADS” clustering software was applied.

Gene annotation—Predicted genes and proteins were annotated as follows:

Blast search [Hypertext Transfer Protocol://blast (dot) ncbi (dot) nlm(dot) nih (dot) gov/Blast (dot) cgi] against all plant UniProt[Hypertext Transfer Protocol://World Wide Web (dot) uniprot (dot) org/]sequences was performed. Open reading frames of each putative transcriptwere analyzed and longest ORF with higher number of homologues wasselected as predicted protein of the transcript. The predicted proteinswere analyzed by InterPro [Hypertext Transfer Protocol://World Wide Web(dot) ebi (dot) ac (dot) uk/interpro/].

Blast against proteins from AraCyc and ENZYME databases was used to mapthe predicted transcripts to AraCyc pathways.

Predicted proteins from different species were compared using blastalgorithm [Hypertext Transfer Protocol://World Wide Web (dot) ncbi (dot)nlm (dot) nih (dot) gov/Blast (dot) cgi] to validate the accuracy of thepredicted protein sequence, and for efficient detection of orthologs.

Gene expression profiling—Several data sources were exploited for geneexpression profiling, namely microarray data and digital expressionprofile (see below). According to gene expression profile, a correlationanalysis was performed to identify genes which are co-regulated underdifferent development stages and environmental conditions and associatedwith different phenotypes.

Publicly available microarray datasets were downloaded from TAR and NCBIGEO sites, renormalized, and integrated into the database. Expressionprofiling is one of the most important resource data for identifyinggenes important for yield.

A digital expression profile summary was compiled for each clusteraccording to all keywords included in the sequence records comprisingthe cluster. Digital expression, also known as electronic Northern Blot,is a tool that displays virtual expression profile based on the ESTsequences forming the gene cluster. The tool provides the expressionprofile of a cluster in terms of plant anatomy (e.g., the tissue/organin which the gene is expressed), developmental stage (the developmentalstages at which a gene can be found) and profile of treatment (providesthe physiological conditions under which a gene is expressed such asdrought, cold, pathogen infection, etc). Given a random distribution ofESTs in the different clusters, the digital expression provides aprobability value that describes the probability of a cluster having atotal of N ESTs to contain X ESTs from a certain collection oflibraries. For the probability calculations, the following is taken intoconsideration: a) the number of ESTs in the cluster, b) the number ofESTs of the implicated and related libraries, c) the overall number ofESTs available representing the species. Thereby clusters with lowprobability values are highly enriched with ESTs from the group oflibraries of interest indicating a specialized expression.

Recently, the accuracy of this system was demonstrated by Portnoy etal., 2009 (Analysis Of The Melon Fruit Transcriptome Based On 454Pyrosequencing) in: Plant & Animal Genomes XVII Conference, San Diego,Calif. Transcriptomic analysis, based on relative EST abundance in datawas performed by 454 pyrosequencing of cDNA representing mRNA of themelon fruit. Fourteen double strand cDNA samples obtained from twogenotypes, two fruit tissues (flesh and rind) and four developmentalstages were sequenced. GS FLX pyrosequencing (Roche/454 Life Sciences)of non-normalized and purified cDNA samples yielded 1,150,657 expressedsequence tags, that assembled into 67,477 unigenes (32,357 singletonsand 35,120 contigs). Analysis of the data obtained against the CucurbitGenomics Database [Hypertext Transfer Protocol://World Wide Web (dot)icugi (dot) org/] confirmed the accuracy of the sequencing and assembly.Expression patterns of selected genes fitted well their qRT-PCR data.

To further investigate and identify putative orthologs of the yield,growth rate, vigor, biomass, growth rate, abiotic stress tolerance(ABST), nitrogen use efficiency (NUE) and fertilizer use efficiency(FUE) genes from other plant species, expression data was analyzed andthe EST libraries were classified using a fixed vocabulary of customterms such as developmental stages (e.g., genes showing similarexpression profile through development with up regulation at specificstage, such as at the seed filling stage) and/or plant organ (e.g.,genes showing similar expression profile across their organs with upregulation at specific organs such as seed). The annotations from allthe ESTs clustered to a gene were analyzed statistically by comparingtheir frequency in the cluster versus their abundance in the database,allowing to construct a numeric and graphic expression profile of thatgene, which is termed “digital expression”. The rationale of using thesetwo complementary methods with methods of phenotypic association studiesof QTLs, SNPs and phenotype expression correlation is based on theassumption that true orthologs are likely to retain identical functionover evolutionary time. These methods provide different sets ofindications on function similarities between two homologous genes,similarities in the sequence level—identical amino acids in the proteindomains and similarity in expression profiles.

Overall, 239 genes were identified to have a major impact on plantyield, growth rate, vigor, biomass, growth rate, oil content, abioticstress tolerance, nitrogen use efficiency, water use efficiency andfertilizer use efficiency when expression thereof is increased inplants. The identified genes, their curated polynucleotide andpolypeptide sequences, as well as their updated sequences according toGenbank database are summarized in Table 1, hereinbelow.

TABLE 1 Identified genes for increasing yield, growth rate, vigor,biomass, growth rate, oil content, abiotic stress tolerance, nitrogenuse efficiency, water use efficiency and fertilizer use efficiency of aplant Gene Polynucleotide Polypeptide Name Cluster Name Organism SEQ IDNO: SEQ ID NO: LYM1 rice|gb157.2|AU058137 rice 1 240 LYM2rice|gb157.2|AA750140 rice 2 241 LYM3 rice|gb157.2|AU032158 rice 3 242LYM4 rice|gb157.2|AU082697 rice 4 243 LYM5 rice|gb157.2|AW155107 rice 5244 LYM6 rice|gb157.2|AW155114 rice 6 245 LYM7 rice|gb157.2|BE039635rice 7 246 LYM8 rice|gb157.2|BE040233 rice 8 247 LYM9rice|gb157.2|BE040806 rice 9 248 LYM10 rice|gb157.2|BE230434 rice 10 249LYM12 rice|gb157.2|BI807331 rice 11 250 LYM13 rice|gb157.2|BM037844 rice12 251 LYM14 rice|gb157.2|BM038118 rice 13 252 LYM15rice|gb157.2|CA761603 rice 14 253 LYM16 rice|gb157.2|U38074 rice 15 254LYM17 rice|gb157.2|AU033038 rice 16 255 LYM19 rice|gb157.2|BE040457 rice17 256 LYM20 rice|gb157.2|BF430570 rice 18 257 LYM21rice|gb157.2|BI805660 rice 19 258 LYM22 rice|gb157.2|BI808357 rice 20259 LYM23 rice|gb157.2|AA749984 rice 21 260 LYM24 rice|gb157.2|AF050674rice 22 261 LYM26 barley|gb157.3|AJ431915 barley 23 262 LYM30rice|gb157.2|AK100743 rice 24 263 LYM31 rice|gb157.2|AK101734 rice 25264 LYM32 rice|gb157.2|AK106380 rice 26 265 LYM34 rice|gb157.2|AK107902rice 27 266 LYM35 rice|gb157.2|AK107934 rice 28 267 LYM36rice|gb157.2|AK108674 rice 29 268 LYM37 rice|gb157.2|AK111353 rice 30269 LYM38 barley|gb157.3|AL508889 barley 31 270 LYM40rice|gb157.2|AU082329 rice 32 271 LYM41 rice|gb157.2|AU096202 rice 33272 LYM42 rice|gb157.2|AU097348 rice 34 273 LYM43 rice|gb157.2|AU101198rice 35 274 LYM44 rice|gb157.2|AU172519 rice 36 275 LYM49maize|gb164|AW331061 maize 37 LYM51 barley|gb157.3|BE412472 barley 38276 LYM52 barley|gb157.3|BE422132 barley 39 277 LYM53maize|gb164|BE511332 maize 40 278 LYM56 barley|gb157.3|BF625411 barley41 279 LYM57 rice|gb157.2|BI809626 rice 42 280 LYM59barley|gb157.3|BI952737 barley 43 LYM61 maize|gb164|BM079029 maize 44281 LYM62 maize|gb164|BM348041 maize 45 282 LYM66barley|gb157.3|BU974981 barley 46 283 LYM67 rice|gb157.2|CA763759 rice47 284 LYM68 rice|gb157.2|CA767240 rice 48 285 LYM69rice|gb157.2|CA997856 rice 49 286 LYM73 rice|gb157.2|CB683204 rice 50287 LYM74 maize|gb164|CF075309 maize 51 288 LYM79 maize|gb164|AW191191maize 52 289 LYM82 barley|gb157.3|AL507706 barley 53 290 LYM83barley|gb157.3|BI952401 barley 54 291 LYM84 barley|gb157.3|BF622069barley 55 292 LYM86 rice|gb157.2|AU031857 rice 56 293 LYM88arabidopsis|gb165|AT2G37750 arabidopsis 57 294 LYM89arabidopsis|gb165|AT5G67490 arabidopsis 58 295 LYM90barley|gb157.3|AV927104 barley 59 296 LYM91 barley|gb157.3|BE060518barley 60 297 LYM93 barley|gb157.3|BI955752 barley 61 298 LYM99barley|gb157.3|BI947870 barley 62 299 LYM95 barley|gb157.3|BI959932barley 63 300 LYM100 barley|gb157.3|AV912944 barley 64 301 LYM102rice|gb157.2|CA760613 rice 65 302 LYM103 maize|gb164|CD963970 maize 66303 LYM105 barley|gb157.3|AL507901 barley 67 304 LYM106barley|gb157.3|BI954225 barley 68 305 LYM110 maize|gb164|BE552618 maize69 306 LYM111 maize|gb164|AW053159 maize 70 307 LYM119maize|gb164|AW498426 maize 71 308 LYM120 rice|gb157.3|BI795677 rice 72309 LYM122 rice|gb157.3|BI118816 rice 73 310 LYM125rice|gb157.2|AK108452 rice 74 311 LYM126 rice|gb157.2|AK108969 rice 75312 LYM127 rice|gb157.2|AU172589 rice 76 313 LYM128rice|gb157.2|AU172667 rice 77 314 LYM129 rice|gb157.3|BE230206 rice 78315 LYM130 rice|gb157.3|BF430580 rice 79 316 LYM131rice|gb157.3|CF309827 rice 80 317 LYM132 rice|gb157.3|BE229876 rice 81318 LYM134 rice|gb157.2|BI809462 rice 82 319 LYM136rice|gb157.2|AU093861 rice 83 320 LYM137 barley|gb157.3|AL501911 barley84 321 LYM140 barley|gb157.3|BF623993 barley 85 322 LYM141rice|gb157.2|CA761074 rice 86 323 LYM142 barley|gb157.3|CB866504 barley87 324 LYM143 rice|gb157.3|BI306405 rice 88 325 LYM144rice|gb157.2|BM420331 rice 89 326 LYM145 rice|gb157.2|AK073109 rice 90327 LYM148 barley|gb157.3|AL500574 barley 91 328 LYM149barley|gb157.3|AL509762 barley 92 329 LYM152 arabidopsis|gb165|AT5G57290arabidopsis 93 330 LYM153 rice|gb157.3|AU066244 rice 94 331 LYM156barley|gb157.3|BE421631 barley 95 332 LYM157 barley|gb157.3|BE454937barley 96 333 LYM159 barley|gb157.3|BF259387 barley 97 334 LYM160barley|gb157.3|BG300909 barley 98 335 LYM161 barley|gb157.3|BG344928barley 99 336 LYM162 maize|gb164|BG462213 maize 100 337 LYM164rice|gb157.3|BI805693 rice 101 338 LYM165 maize|gb164|CD439546 maize 102339 LYM166 wheat|gb164|CJ547519 wheat 103 340 LYM170rice|gb157.2|AU057403 rice 104 341 LYM172 rice|gb157.2|BE229411 rice 105342 LYM173 rice|gb157.3|AA751564 rice 106 343 LYM174sorghum|gb161.crp|AW284303 sorghum 107 344 LYM175 rice|gb157.2|AK060073rice 108 345 LYM176 rice|gb157.2|BI305434 rice 109 346 LYM178barley|gb157.3|BE421520 barley 110 347 LYM179 maize|gb164|BE051631 maize111 348 LYM107 maize|gb164|AW497895 maize 112 349 LYM109maize|gb169.2|CD984002 maize 113 350 LYM112 maize|gb164|CF038223 maize114 351 LYM113 maize|gb164|AW257902 maize 115 352 LYM115maize|gb164|CF646135 maize 116 353 LYM116 maize|gb164|AI964572 maize 117354 LYM117 maize|gb164|AI739834 maize 118 355 LYM118maize|gb164|CO518843 maize 119 356 LYM121 rice|gb157.2|AK103124 rice 120357 LYM123 rice|gb157.2|AI978352 rice 121 358 LYM135rice|gb157.2|AU101278 rice 122 359 LYM138 rice|gb157.2|BI805497 rice 123360 LYM146 maize|gb164|AI770878 maize 124 361 LYM147maize|gb164|AI901828 maize 125 362 LYM154 barley|gb157.3|AV836282 barley126 363 LYM155 barley|gb157.3|BE412535 barley 127 364 LYM180barley|gb157.3|AJ476822 barley 128 365 LYM181 barley|gb157.3|AL450622barley 129 366 LYM182 barley|gb157.3|AL507048 barley 130 367 LYM184barley|gb157.3|AV833284 barley 131 368 LYM185 barley|gb157.3|AV833969barley 132 369 LYM186 barley|gb157.3|AV834971 barley 133 370 LYM188barley|gb157.3|BE438660 barley 134 371 LYM189 barley|gb157.3|BF256192barley 135 372 LYM192 barley|gb157.3|BF627356 barley 136 373 LYM193barley|gb157.3|CB858276 barley 137 374 LYM194 barley|gb157.3|CB860975barley 138 375 LYM196 maize|gb164|AI372352 maize 139 376 LYM197maize|gb164|AI444704 maize 140 377 LYM198 maize|gb164|AI491323 maize 141378 LYM201 maize|gb164|AI600670 maize 142 379 LYM203maize|gb164|AI629486 maize 143 380 LYM204 maize|gb164|AI649791 maize 144381 LYM206 maize|gb164|AI691210 maize 145 382 LYM207maize|gb164|AI920398 maize 146 383 LYM208 maize|gb164|AI941717 maize 147384 LYM212 maize|gb164|AW000408 maize 148 385 LYM213maize|gb164|AW000438 maize 149 386 LYM215 maize|gb164|AW498464 maize 150387 LYM217 maize|gb164|BE129928 maize 151 388 LYM219maize|gb164|BE238495 maize 152 389 LYM220 maize|gb164|BG842756 maize 153390 LYM221 maize|gb164|BI502603 maize 154 391 LYM223maize|gb164|BM338985 maize 155 392 LYM224 maize|gb164|CA401086 maize 156393 LYM227 maize|gb164|EC877515 maize 157 394 LYM228maize|gb164|EC892599 maize 158 395 LYM232 rice|gb157.3|AA750121 rice 159396 LYM233 rice|gb157.3|AA750182 rice 160 397 LYM234rice|gb157.3|AA752388 rice 161 398 LYM236 rice|gb157.3|AF155334 rice 162399 LYM238 rice|gb157.3|AK066551 rice 163 400 LYM239rice|gb157.3|AU068651 rice 164 401 LYM240 rice|gb157.3|AU069131 rice 165402 LYM241 rice|gb157.3|AU162998 rice 166 403 LYM242rice|gb157.3|BE039711 rice 167 404 LYM243 rice|gb157.3|BE228686 rice 168405 LYM245 rice|gb157.3|BF430828 rice 169 406 LYM248rice|gb157.3|BQ906571 rice 170 407 LYM249 rice|gb157.3|C25903 rice 171408 LYM250 rice|gb157.3|CA759158 rice 172 409 LYM251rice|gb157.3|CA759241 rice 173 410 LYM252 rice|gb157.3|CA759659 rice 174411 LYM254 rice|gb157.3|CB657978 rice 175 412 LYM255rice|gb157.3|CF330913 rice 176 413 LYM260 rice|gb157.3|CI581223 rice 177414 LYM261 rice|gb157.3|D41406 rice 178 415 LYM263sorghum|gb161.crp|AI622410 sorghum 179 416 LYM183barley|gb157.3|AL509795 barley 180 417 LYM256 rice|gb157.3|CI004090 rice181 418 LYM200 maize|gb164|AI586731 maize 182 419 LYM267maize|gb164|AW231521 maize 183 420 LYM268 rice|gb157.2|BI800054 rice 184421 LYM270 maize|gb164|AI670268 maize 185 422 LYM271maize|gb164|CF637107 maize 186 423 LYM272 rice|gb157.2|CA761620 rice 187424 LYM273 rice|gb157.2|BM418692 rice 188 425 LYM274rice|gb157.2|AK073201 rice 189 426 LYM277 rice|gb157.2|BM038097 rice 190427 LYM278 barley|gb157.3|BLYTRAA barley 191 428 LYM283rice|gb157.2|D23167 rice 192 429 LYM284 rice|gb157.2|BI306331 rice 193430 LYM285 rice|gb157.2|CB631346 rice 194 431 LYM287rice|gb157.2|AK102063 rice 195 432 LYM288 rice|gb157.2|BE040927 rice 196433 LYM289 barley|gb157.3|AV925962 barley 197 434 LYM290maize|gb164|AA979729 maize 198 435 LYM291 rice|gb157.2|BM037976 rice 199436 LYM293 rice|gb157.2|AK059161 rice 200 437 LYM38barley|gb157.3|AL508889 barley 201 438 LYM42 rice|gb157.2|AU097348 rice202 439 LYM51 barley|gb157.3|BE412472 barley 203 276 LYM52barley|gb157.3|BE422132 barley 204 277 LYM56 barley|gb157.3|BF625411barley 205 279 LYM59 barley|gb157.3|BI952737 barley 206 LYM66barley|gb157.3|BU974981 barley 207 440 LYM79 maize|gb164|AW191191 maize208 441 LYM83 barley|gb157.3|BI952401 barley 209 442 LYM90barley|gb157.3|AV927104 barley 210 296 LYM99 barley|gb157.3|BI947870barley 211 299 LYM95 barley|gb157.3|BI959932 barley 212 443 LYM148barley|gb157.3|AL500574 barley 213 328 LYM159 barley|gb157.3|BF259387barley 214 334 LYM161 barley|gb157.3|BG344928 barley 215 444 LYM166wheat|gb164|CJ547519 wheat 216 445 LYM175 rice|gb157.2|AK060073 rice 217446 LYM109 maize|gb164|CD984002 maize 218 447 LYM112maize|gb164|CF038223 maize 219 448 LYM116 maize|gb164|AI964572 maize 220354 LYM117 maize|gb164|AI739834 maize 221 449 LYM154barley|gb157.3|AV836282 barley 222 450 LYM155 barley|gb157.3|BE412535barley 223 451 LYM180 barley|gb157.3|AJ476822 barley 224 452 LYM181barley|gb157.3|AL450622 barley 225 453 LYM184 barley|gb157.3|AV833284barley 226 454 LYM185 barley|gb157.3|AV833969 barley 227 455 LYM186barley|gb157.3|AV834971 barley 228 370 LYM188 barley|gb157.3|BE438660barley 229 456 LYM189 barley|gb157.3|BF256192 barley 230 457 LYM192barley|gb157.3|BF627356 barley 231 458 LYM193 barley|gb157.3|CB858276barley 232 459 LYM194 barley|gb157.3|CB860975 barley 233 460 LYM219maize|gb164|BE238495 maize 234 389 LYM221 maize|gb164|BI502603 maize 235461 LYM228 maize|gb164|EC892599 maize 236 462 LYM250rice|gb157.3|CA759158 rice 237 463 LYM183 barley|gb157.3|AL509795 barley238 464 LYM272 rice|gb157.2|CA761620 rice 239 465 Table 1: Provided arethe identified genes, their annotation, organism and polynucleotide andpolypeptide sequence identifiers.

Example 2 Identification of Homologous Sequences that Increase Yield,Fiber Yield, Fiber Quality, Growth Rate, Biomass, Oil Content, Vigor,Abst, and/or Nue of a Plant

The concepts of orthology and paralogy have recently been applied tofunctional characterizations and classifications on the scale ofwhole-genome comparisons. Orthologs and paralogs constitute two majortypes of homologs: The first evolved from a common ancestor byspecialization, and the latter are related by duplication events. It isassumed that paralogs arising from ancient duplication events are likelyto have diverged in function while true orthologs are more likely toretain identical function over evolutionary time.

To identify putative orthologs of the genes affecting plant yield, oilyield, oil content, seed yield, growth rate, vigor, biomass, abioticstress tolerance and/or nitrogen use efficiency, all sequences werealigned using the BLAST (Basic Local Alignment Search Tool). Sequencessufficiently similar were tentatively grouped. These putative orthologswere further organized under a Phylogram—a branching diagram (tree)assumed to be a representation of the evolutionary relationships amongthe biological taxa. Putative ortholog groups were analyzed as to theiragreement with the phylogram and in cases of disagreements theseortholog groups were broken accordingly.

Expression data was analyzed and the EST libraries were classified usinga fixed vocabulary of custom terms such as developmental stages (e.g.,genes showing similar expression profile through development with upregulation at specific stage, such as at the seed filling stage) and/orplant organ (e.g., genes showing similar expression profile across theirorgans with up regulation at specific organs such as seed). Theannotations from all the ESTs clustered to a gene were analyzedstatistically by comparing their frequency in the cluster versus theirabundance in the database, allowing the construction of a numeric andgraphic expression profile of that gene, which is termed “digitalexpression”. The rationale of using these two complementary methods withmethods of phenotypic association studies of QTLs, SNPs and phenotypeexpression correlation is based on the assumption that true orthologsare likely to retain identical function over evolutionary time. Thesemethods provide different sets of indications on function similaritiesbetween two homologous genes, similarities in the sequencelevel—identical amino acids in the protein domains and similarity inexpression profiles.

The search and identification of homologous genes involves the screeningof sequence information available, for example, in public databases suchas the DNA Database of Japan (DDBJ), Genbank, and the European MolecularBiology Laboratory Nucleic Acid Sequence Database (EMBL) or versionsthereof or the MIPS database. A number of different search algorithmshave been developed, including but not limited to the suite of programsreferred to as BLAST programs. There are five implementations of BLAST,three designed for nucleotide sequence queries (BLASTN, BLASTX, andTBLASTX) and two designed for protein sequence queries (BLASTP andTBLASTN) (Coulson, Trends in Biotechnology: 76-80, 1994; Birren et al.,Genome Analysis, I: 543, 1997). Such methods involve alignment andcomparison of sequences. The BLAST algorithm calculates percent sequenceidentity and performs a statistical analysis of the similarity betweenthe two sequences. The software for performing BLAST analysis ispublicly available through the National Centre for BiotechnologyInformation. Other such software or algorithms are GAP, BESTFIT, FASTAand TFASTA. GAP uses the algorithm of Needleman and Wunsch (J. Mol.Biol. 48: 443-453, 1970) to find the alignment of two complete sequencesthat maximizes the number of matches and minimizes the number of gaps.

The homologous genes may belong to the same gene family. The analysis ofa gene family may be carried out using sequence similarity analysis. Toperform this analysis one may use standard programs for multiplealignments e.g. Clustal W. A neighbour-joining tree of the proteinshomologous to the genes in this invention may be used to provide anoverview of structural and ancestral relationships. Sequence identitymay be calculated using an alignment program as described above. It isexpected that other plants will carry a similar functional gene(ortholog) or a family of similar genes and those genes will provide thesame preferred phenotype as the genes presented here. Advantageously,these family members may be useful in the methods of the invention.Example of other plants are included here but not limited to, barley(Hordeum vulgare), Arabidopsis (Arabidopsis thaliana), maize (Zea mays),cotton (Gossypium), Oilseed rape (Brassica napus), Rice (Oryza sativa),Sugar cane (Saccharum officinarum), Sorghum (Sorghum bicolor), Soybean(Glycine max), Sunflower (Helianthus annuus), Tomato (Lycopersiconesculentum), Wheat (Triticum aestivum).

The above-mentioned analyses for sequence homology can be carried out ona full-length sequence, but may also be based on a comparison of certainregions such as conserved domains. The identification of such domains,would also be well within the realm of the person skilled in the art andwould involve, for example, a computer readable format of the nucleicacids of the present invention, the use of alignment software programsand the use of publicly available information on protein domains,conserved motifs and boxes. This information is available in the PRODOM(Hypertext Transfer Protocol://World Wide Web (dot) biochem (dot) ucl(dot) ac (dot) uk/bsm/dbbrowser/protocol/prodomqry (dot) html), PR(Hypertext Transfer Protocol://pir (dot) Georgetown (dot) edu/) or Pfam(Hypertext Transfer Protocol://World Wide Web (dot) sanger (dot) ac(dot) uk/Software/Pfam/) database. Sequence analysis programs designedfor motif searching may be used for identification of fragments, regionsand conserved domains as mentioned above. Preferred computer programsinclude, but are not limited to, MEME, SIGNALSCAN, and GENESCAN.

A person skilled in the art may use the homologous sequences providedherein to find similar sequences in other species and other organisms.Homologues of a protein encompass, peptides, oligopeptides,polypeptides, proteins and enzymes having amino acid substitutions,deletions and/or insertions relative to the unmodified protein inquestion and having similar biological and functional activity as theunmodified protein from which they are derived. To produce suchhomologues, amino acids of the protein may be replaced by other aminoacids having similar properties (conservative changes, such as similarhydrophobicity, hydrophilicity, antigenicity, propensity to form orbreak a-helical structures or 3-sheet structures). Conservativesubstitution tables are well known in the art (see for example Creighton(1984) Proteins. W. H. Freeman and Company). Homologues of a nucleicacid encompass nucleic acids having nucleotide substitutions, deletionsand/or insertions relative to the unmodified nucleic acid in questionand having similar biological and functional activity as the unmodifiednucleic acid from which they are derived.

Table 2, hereinbelow, lists a summary of orthologous and homologoussequences of the polynucleotide sequences (SEQ ID NOs:1-239) andpolypeptide sequences (SEQ ID NOs:240-465) presented in Table 1 above,which were identified from the databases using the NCBI BLAST software(e.g., using the Blastp and tBlastn algorithms) and needle (EMBOSSpackage) as being at least 80% homologous to the selectedpolynucleotides and polypeptides, and which are expected to increaseplant yield, seed yield, oil yield, oil content, growth rate, fiberyield, fiber quality, biomass, vigor, ABST and/or NUE of a plant.

TABLE 2 Homologues of the identified genes/polypeptides for increasingyield, fiber yield, fiber quality, growth rate, vigor, biomass, growthrate, abiotic stress tolerance, nitrogen use efficiency, water useefficiency and fertilizer use efficiency of a plant Polyp. Homolog. %Nucl. SEQ SEQ ID to SEQ ID global ID NO: Gene Name cluster name NO: NO:identity Algor. 467 LYM2 H5 brachypodium|09v1|DV480246 1974 241 89.1blastp 468 LYM2 H6 maize|gb170|AW224918 1975 241 86.6 blastp 469 LYM2 H7millet|09v1|EVO454PM002089 1976 241 87.6 blastp 470 LYM2 H8sorghum|09v1|SB07G004285 1977 241 86.6 blastp 471 LYM2 H4switchgrass|gb167|FE606998 1978 241 89.9 blastp 472 LYM2 H5wheat|gb164|BM136811 1979 241 80.53 tblastn 473 LYM4 H6barley|gb157SOLEXA| 1980 243 81.5 blastp BE438934 474 LYM4 H7brachypodium|09v1|DV469575 1981 243 81.5 blastp 475 LYM4 H2cenchrus|gb166|BM084020 1982 243 83 blastp 476 LYM4 H8maize|gb170|AI600994 1983 243 82.2 blastp 477 LYM4 H9maize|gb170|AW054478 1984 243 82.4 blastp 478 LYM4 H10rice|gb170|OS05G13950 1985 243 94.7 blastp 479 LYM4 H11sorghum|09v1|SB03G000920 1986 243 83.2 blastp 480 LYM4 H5switchgrass|gb167|FL703533 1987 243 83 blastp 481 LYM4 H6wheat|gb164|BE444991 1988 243 81.3 blastp 482 LYM5 H16barley|gb157SOLEXA| 1989 244 90.9 blastp BI953887 483 LYM5 H17brachypodium|09v1|DV474010 1990 244 91.3 blastp 484 LYM5 H3cenchrus|gb166|EB655978 1991 244 88.19 tblastn 485 LYM5 H4fescue|gb161|DT688132 1992 244 85.8 blastp 486 LYM5 H5leymus|gb166|EG394968 1993 244 90.9 blastp 487 LYM5 H18maize|gb170|AI783290 1994 244 92.1 blastp 488 LYM5 H19maize|gb170|BG265158 1995 244 92.5 blastp 489 LYM5 H20rice|gb170|OS02G46660 1996 244 87.8 blastp 490 LYM5 H21sorghum|09v1|SB04G031180 1997 244 80.3 blastp 491 LYM5 H22sorghum|09v1|SB06G027060 1998 244 90.9 blastp 492 LYM5 H23sugarcane|gb157.3|CA118359 1999 244 91.7 blastp 493 LYM5 H12switchgrass|gb167|FE641223 2000 244 93.3 blastp 494 LYM5 H13switchgrass|gb167|FL708642 2001 244 92.5 blastp 495 LYM5 H14wheat|gb164|BE414733 2002 244 90.6 blastp 496 LYM5 H15wheat|gb164|BE431026 2003 244 91.3 blastp 497 LYM5 H16wheat|gb164|CA613380 2004 244 90.9 blastp 498 LYM7 H35 b 2005 246 81.2blastp oleracea|gb161|AM057184 499 LYM7 H36 barley|gb157SOLEXA| 2006 24682.6 blastp BE413128 500 LYM7 H37 barley|gb157SOLEXA| 2007 246 95.7blastp BF627706 501 LYM7 H38 brachypodium|09v1|DV468966 2008 246 94.2blastp 502 LYM7 H39 brachypodium|09v1|DV474806 2009 246 82.6 blastp 503LYM7 H6 bruguiera|gb166|BP945554 2010 246 81.2 blastp 504 LYM7 H40canola|gb161|CD811653 2011 246 81.2 blastp 505 LYM7 H41canola|gb161|CD838423 2012 246 81.2 blastp 506 LYM7 H42cassava|09v1|CK652348 2013 246 82.6 blastp 507 LYM7 H43castorbean|09v1|XM002532394 2014 246 82.6 blastp 508 LYM7 H44cucumber|09v1|AM717859 2015 246 82.6 blastp 509 LYM7 H9eucalyptus|gb166|CB967858 2016 246 81.2 blastp 510 LYM7 H10kiwi|gb166|FG431017 2017 246 81.2 blastp 511 LYM7 H11kiwi|gb166|FG521634 2018 246 82.6 blastp 512 LYM7 H12liriodendron|gb166|FD494835 2019 246 82.6 blastp 513 LYM7 H45maize|gb170|AI943908 2020 246 82.6 blastp 514 LYM7 H46maize|gb170|AW282244 2021 246 88.4 blastp 515 LYM7 H47maize|gb170|LLAI855232 2022 246 82.61 tblastn 516 LYM7 H48maize|gb170|LLDN209190 2023 246 82.61 tblastn 517 LYM7 H49millet|09v1|EVO454PM003641 2024 246 91.3 blastp 518 LYM7 H50millet|09v1|EVO454PM019125 2025 246 81.2 blastp 519 LYM7 H16oat|gb164|CN817490 2026 246 88.4 blastp 520 LYM7 H17 oat|gb164|CN8196432027 246 82.6 blastp 521 LYM7 H51 poplar|gb170|BI069446 2028 246 81.2blastp 522 LYD97 poplar|gb170|BI123662 2029 246 81.2 blastp H18 523 LYM7H20 rye|gb164|BE496021 2030 246 94.2 blastp 524 LYM7 H21rye|gb164|BE587226 2031 246 81.2 blastp 525 LYM7 H52sorghum|09v1|SB05G003875 2032 246 88.4 blastp 526 LYM7 H53sugarcane|gb157.3|CA079082 2033 246 89.9 blastp 527 LYM7 H54sugarcane|gb157.3|CA158782 2034 246 81.2 blastp 528 LYM7 H25switchgrass|gb167|DN149707 2035 246 82.6 blastp 529 LYM7 H26switchgrass|gb167|FE644021 2036 246 84.1 blastp 530 LYM7 H27switchgrass|gb167|FE657215 2037 246 80 blastp 531 LYM7 H28switchgrass|gb167|FE658413 2038 246 88.4 blastp 532 LYM7 H29switchgrass|gb167|FL689692 2039 246 88.4 blastp 533 LYM7 H30wheat|gb164|BE404350 2040 246 81.2 blastp 534 LYM7 H31wheat|gb164|BE414371 2041 246 84.1 blastp 535 LYM7 H32wheat|gb164|BE430017 2042 246 94.2 blastp 536 LYM7 H33wheat|gb164|BE444058 2043 246 95.7 blastp 537 LYM7 H34wheat|gb164|BE444789 2044 246 82.6 blastp 538 LYM7 H35wheat|gb164|CA598363 2045 246 95.7 blastp 539 LYM8 H7 arabidopsis 2046247 80.2 blastp lyrata|09v1|JGIAL008627 540 LYM8 H8 arabidopsis 2047 24783.3 blastp lyrata|09v1|JGIAL021400 541 LYM8 H1arabidopsis|gb165|AT3G03110 2048 247 80.6 blastp 542 LYM8 H2arabidopsis|gb165|AT5G17020 2049 247 82.9 blastp 543 LYM8 H9brachypodium|09v1|GT774368 2050 247 95.6 blastp 544 LYM8 H10castorbean|09v1|EE255045 2051 247 84.2 blastp 545 LYM8 H11chestnut|gb170|SRR006295S0059698 2052 247 85.7 blastp 546 LYM8 H12cucumber|09v1|GD174631 2053 247 84.5 blastp 547 LYM8 H13lotus|09v1|BP043858 2054 247 83.8 blastp 548 LYM8 H14lotus|09v1|BP071708 2055 247 83.6 blastp 549 LYM8 H15maize|gb170|AA030709 2056 247 92.1 blastp 550 LYM8 H16maize|gb170|AI621522 2057 247 92.2 blastp 551 LYM8 H17medicago|09v1|BE205102 2058 247 83.5 blastp 552 LYM8 H18medicago|09v1|BM779128 2059 247 83.9 blastp 553 LYM8 H19poplar|gb170|BI127444 2060 247 84.8 blastp 554 LYM8 H20poplar|gb170|BU837911 2061 247 85 blastp 555 LYM8 H21rice|gb170|OS03G64080 2062 247 99.72 tblastn 556 LYM8 H22 solanum 2063247 83.2 blastp phureja|09v1|SPHBG128228 557 LYM8 H23sorghum|09v1|SB01G000490 2064 247 93.9 blastp 558 LYM8 H24sorghum|09v1|SB02G009800 2065 247 89 blastp 559 LYM8 H6soybean|gb168|BE205102 2066 247 82.98 tblastn 560 LYM8 H7soybean|gb168|BE823809 2067 247 81.6 blastp 561 LYM8 H25tomato|09v1|BG128228 2068 247 83.33 tblastn 562 LYM9 H0lolium|09v1|AU245599 2069 248 80.1 blastp 563 LYM10 H1antirrhinum|gb166|AJ786992 2070 249 89.9 blastp 564 LYM10apple|gb171|CN443929 2071 249 91.3 blastp H207 565 LYM10apple|gb171|CN489763 2072 249 91.3 blastp H208 566 LYM10apple|gb171|CN874192 2073 249 87 blastp H209 567 LYM10 arabidopsis 2074249 85.5 blastp H210 lyrata|09v1|JGIAL017989 568 LYM10 arabidopsis 2075249 91.3 blastp H211 lyrata|09v1|JGIAL025614 569 LYM10 arabidopsis 2076249 91.3 blastp H212 lyrata|09v1|JGIAL029470 570 LYM10 H7arabidopsis|gb165|AT3G48570 2077 249 85.5 blastp 571 LYM10 H8arabidopsis|gb165|AT4G24920 2078 249 91.3 blastp 572 LYM10 H9arabidopsis|gb165|AT5G50460 2079 249 91.3 blastp 573 LYM10artemisia|gb164|EX980216 2080 249 88.4 blastp H10 574 LYM10 b 2081 24985.5 blastp H11 juncea|gb164|EVGN00323614690486 575 LYM10 b 2082 24981.16 tblastn H12 juncea|gb164|EVGN00357611620134 576 LYM10 b 2083 24991.3 blastp H13 juncea|gb164|EVGN00407015981886 577 LYM10 b 2084 24991.3 blastp H14 juncea|gb164|EVGN01046711722157 578 LYM10 b 2085 24991.3 tblastn H15 juncea|gb164|EVGN01350404310247 579 LYM10 b 2086 24991.3 blastp H16 juncea|gb164|EVGN01826229072660 580 LYM10 b 2087 24986.3 blastp H17 juncea|gb164|EVGN10412810992898 581 LYM10 b 2088 24981.2 blastp H18 juncea|gb164|EVGN19578802581818 582 LYM10 b 2089 24991.3 blastp H19 oleracea|gb161|AM059639 583 LYM10 b 2090 249 91.3 blastpH20 oleracea|gb161|EH414574 584 LYM10 b 2091 249 81.7 blastp H21oleracea|gb161|EH427198 585 LYM10 b 2092 249 91.3 blastp H22rapa|gb162|BG544908 586 LYM10 b 2093 249 91.3 blastp H23rapa|gb162|DY010003 587 LYM10 b 2094 249 91.3 tblastn H24rapa|gb162|EE524434 588 LYM10 b rapa|gb162|L35825 2095 249 91.3 blastpH25 589 LYM10 banana|gb167|DN239748 2096 249 94.2 blastp H26 590 LYM10banana|gb167|ES432517 2097 249 95.7 blastp H27 591 LYM10banana|gb167|FL649789 2098 249 95.7 blastp H28 592 LYM10banana|gb167|FL658161 2099 249 94.2 blastp H29 593 LYM10barley|gb157SOLEXA| 2100 249 100 blastp H213 AJ433765 594 LYM10barley|gb157SOLEXA| 2101 249 100 blastp H214 BE412470 595 LYM10barley|gb157SOLEXA| 2102 249 98.6 blastp H215 BF254576 596 LYM10barley|gb157SOLEXA| 2103 249 100 blastp H216 BF257015 597 LYM10bean|gb167|CA907476 2104 249 92.75 tblastn H34 598 LYM10bean|gb167|CA907483 2105 249 94.2 blastp H35 599 LYM10beech|gb170|SRR006293S0011456 2106 249 92.8 blastp H217 600 LYM10beech|gb170|SRR006294S0008365 2107 249 88.4 blastp H218 601 LYM10brachypodium|09v1|DV469126 2108 249 100 blastp H219 602 LYM10brachypodium|09v1|GT803631 2109 249 92.8 blastp H220 603 LYM10bruguiera|gb166|BP941922 2110 249 95.7 blastp H38 604 LYM10bruguiera|gb166|BP944773 2111 249 95.7 blastp H39 605 LYM10cacao|gb167|CU471529 2112 249 94.2 blastp H40 606 LYM10cacao|gb167|CU480597 2113 249 84.1 blastp H41 607 LYM10cacao|gb167|CU493298 2114 249 89.9 blastp H42 608 LYM10canola|gb161|CD813231 2115 249 91.3 tblastn H43 609 LYM10canola|gb161|CD817528 2116 249 91.3 tblastn H44 610 LYM10canola|gb161|CD820075 2117 249 91.3 tblastn H45 611 LYM10canola|gb161|CD824239 2118 249 91.3 tblastn H46 612 LYM10canola|gb161|CD838062 2119 249 86.3 blastp H47 613 LYM10canola|gb161|CD840808 2120 249 91.3 blastp H48 614 LYM10canola|gb161|CN732434 2121 249 91.3 tblastn H49 615 LYM10canola|gb161|DW999288 2122 249 91.3 blastp H50 616 LYM10canola|gb161|EE434176 2123 249 84.1 blastp H51 617 LYM10canola|gb161|EE464036 2124 249 87 blastp H52 618 LYM10cassava|09v1|CK642225 2125 249 94.2 blastp H221 619 LYM10cassava|09v1|DV455717 2126 249 94.2 blastp H222 620 LYM10cassava|09v1|FF380389 2127 249 94.2 blastp H223 621 LYM10castorbean|09v1|EG664279 2128 249 92.8 blastp H224 622 LYM10castorbean|09v1|XM002509459 2129 249 91.3 blastp H225 623 LYM10catharanthus|gb166|EG560643 2130 249 91.3 blastp H58 624 LYM10catharanthus|gb166|FD416462 2131 249 91.3 blastp H59 625 LYM10catharanthus|gb166|FD420164 2132 249 92.8 blastp H60 626 LYM10centaurea|gb166|EH747070 2133 249 87 blastp H61 627 LYM10centaurea|gb166|EH788831 2134 249 89.9 blastp H62 628 LYM10chestnut|gb170|SRR006295S0002470 2135 249 95.7 blastp H226 629 LYM10chestnut|gb170|SRR006295S0013318 2136 249 92.8 blastp H227 630 LYM10cichorium|gb171|FL673304 2137 249 85.51 tblastn H228 631 LYM10citrus|gb166|CF417520 2138 249 91.3 blastp H63 632 LYM10coffea|gb157.2|DV666460 2139 249 91.3 blastp H64 633 LYM10coffea|gb157.2|DV676797 2140 249 89.86 tblastn H65 634 LYM10cotton|gb164|BE052198 2141 249 94.2 blastp H66 635 LYM10cotton|gb164|BQ404833 2142 249 95.7 blastp H67 636 LYM10cotton|gb164|BQ407407 2143 249 92.8 blastp H68 637 LYM10cotton|gb164|CK640593 2144 249 95.7 blastp H69 638 LYM10cotton|gb164|DT052759 2145 249 88 blastp H70 639 LYM10cotton|gb164|DT574061 2146 249 80.7 blastp H71 640 LYM10cowpea|gb166|FF386543 2147 249 94.2 blastp H72 641 LYM10cowpea|gb166|FF389357 2148 249 94.2 tblastn H73 642 LYM10cryptomeria|gb166|BP174192 2149 249 89.9 blastp H74 643 LYM10cryptomeria|gb166|BP174931 2150 249 88.6 blastp H75 644 LYM10cucumber|09v1|AM715093 2151 249 88.41 tblastn H229 645 LYM10cucumber|09v1|AM720495 2152 249 98.6 blastp H230 646 LYM10cucumber|09v1|DN909507 2153 249 95.7 blastp H231 647 LYM10cycas|gb166|CB091499 2154 249 88.4 blastp H76 648 LYM10cynara|gb167|GE589284 2155 249 88.4 blastp H77 649 LYM10dandelion|gb161|DY811008 2156 249 88.41 tblastn H78 650 LYM10dandelion|gb161|DY839599 2157 249 89.86 tblastn H79 651 LYM10eucalyptus|gb166|CD669252 2158 249 92.8 blastp H80 652 LYM10fern|gb171|DK961389 2159 249 88.4 blastp H232 653 LYM10fescue|gb161|DT702292 2160 249 100 tblastn H81 654 LYM10fescue|gb161|DT704458 2161 249 100 tblastn H82 655 LYM10flax|09v1|EU829193 2162 249 92.8 blastp H233 656 LYM10gerbera|09v1|AJ761193 2163 249 89.9 blastp H234 657 LYM10gerbera|09v1|AJ765913 2164 249 84.1 blastp H235 658 LYM10ginger|gb164|DY368424 2165 249 95.65 tblastn H83 659 LYM10ginger|gb164|DY382125 2166 249 94.2 blastp H84 660 LYM10grape|gb160|BQ793552 2167 249 91.3 blastp H85 661 LYM10grape|gb160|CA809997 2168 249 91.3 blastp H86 662 LYM10iceplant|gb164|AI943423 2169 249 88.4 blastp H87 663 LYM10ipomoea|gb157.2|BJ553479 2170 249 89.86 tblastn H88 664 LYM10ipomoea|gb157.2|CB329955 2171 249 88.41 tblastn H89 665 LYM10ipomoea|gb157.2|CJ751960 2172 249 88.4 blastp H90 666 LYM10jatropha|09v1|GO247649 2173 249 94.2 blastp H236 667 LYM10kiwi|gb166|FG397070 2174 249 89.9 blastp H91 668 LYM10kiwi|gb166|FG477805 2175 249 95.7 blastp H92 669 LYM10lettuce|gb157.2|DW047717 2176 249 88.4 blastp H93 670 LYM10lettuce|gb157.2|DW051281 2177 249 89.9 blastp H94 671 LYM10lettuce|gb157.2|DW080235 2178 249 82.61 tblastn H95 672 LYM10lettuce|gb157.2|DW101958 2179 249 88.4 blastp H96 673 LYM10lettuce|gb157.2|DW123456 2180 249 88.41 tblastn H97 674 LYM10liquorice|gb171|FS242287 2181 249 94.2 blastp H237 675 LYM10liriodendron|gb166|FD495465 2182 249 95.7 blastp H98 676 LYM10liriodendron|gb166|FD500844 2183 249 94.2 blastp H99 677 LYM10lolium|09v1|AU247819 2184 249 98.6 blastp H238 678 LYM10lotus|09v1|CB827059 2185 249 92.8 blastp H239 679 LYM10lotus|09v1|DN652280 2186 249 89.9 blastp H240 680 LYM10lovegrass|gb167|DN482980 2187 249 98.6 blastp H102 681 LYM10maize|gb170|AI001340 2188 249 97.1 blastp H241 682 LYM10maize|gb170|AI665512 2189 249 98.6 blastp H242 683 LYM10maize|gb170|AI677195 2190 249 97.1 blastp H243 684 LYM10maize|gb170|LLAI619401 2191 249 97.1 blastp H244 685 LYM10maize|gb170|LLCF003156 2192 249 81.16 tblastn H245 686 LYM10maize|gb170|LLDQ245943 2193 249 98.6 blastp H246 687 LYM10maize|gb170|W21637 2194 249 98.6 blastp H247 688 LYM10marchantia|gb166|BJ844102 2195 249 87 blastp H109 689 LYM10medicago|09v1|AA660461 2196 249 94.2 blastp H248 690 LYM10medicago|09v1|AW287868 2197 249 94.2 blastp H249 691 LYM10medicago|09v1|LLBQ138650 2198 249 85.5 blastp H250 692 LYM10melon|gb165|AM715093 2199 249 94.2 tblastn H112 693 LYM10melon|gb165|AM720495 2200 249 98.55 tblastn H113 694 LYM10melon|gb165|DV631710 2201 249 95.7 blastp H114 695 LYM10millet|09v1|CD724432 2202 249 98.6 blastp H251 696 LYM10monkeyflower|09v1|DV208117 2203 249 91.3 blastp H252 697 LYM10nuphar|gb166|CD472502 2204 249 97.1 blastp H116 698 LYM10oak|gb170|SRR006307S0013335 2205 249 94.2 blastp H253 699 LYM10oak|gb170|SRR006307S0023745 2206 249 92.75 tblastn H254 700 LYM170 oil2207 249 92.8 blastp H117 palm|gb166|EL684180 701 LYM10onion|gb162|BQ580148 2208 249 97.1 blastp H118 702 LYM10papaya|gb165|EX279251 2209 249 89.9 blastp H119 703 LYM10peanut|gb171|EE124530 2210 249 94.2 blastp H255 704 LYM10peanut|gb171|EE126680 2211 249 94.2 blastp H256 705 LYM10peanut|gb171|EG028825 2212 249 81.2 blastp H257 706 LYM10peanut|gb171|EG373993 2213 249 94.2 blastp H258 707 LYM10pepper|gb171|CA516679 2214 249 91.3 blastp H259 708 LYM10pepper|gb171|GD053770 2215 249 89.9 blastp H260 709 LYM10petunia|gb171|AF049933 2216 249 87 blastp H261 710 LYM10petunia|gb171|EB174381 2217 249 87 blastp H262 711 LYM10physcomitrella|10v1|AW145358 2218 249 81.2 blastp H263 712 LYM10physcomitrella|10v1|BG361572 2219 249 81.2 blastp H264 713 LYM10pine|gb157.2|AL750813 2220 249 91.3 blastp H133 714 LYM10pine|gb157.2|AW064895 2221 249 91.3 blastp H134 715 LYM10pine|gb157.2|AW226488 2222 249 89.9 blastp H135 716 LYM10poplar|gb170|BI127745 2223 249 92.8 blastp H265 717 LYM10poplar|gb170|BU824190 2224 249 92.8 blastp H266 718 LYM10poplar|gb170|BU862632 2225 249 92.8 blastp H267 719 LYM10poppy|gb166|FE965009 2226 249 88.4 blastp H139 720 LYM10poppy|gb166|FE966430 2227 249 92.8 blastp H140 721 LYM10potato|gb157.2|BG350890 2228 249 91.3 blastp H141 722 LYM10potato|gb157.2|BG589211 2229 249 89.86 tblastn H142 723 LYM10potato|gb157.2|BG592598 2230 249 89.86 tblastn H143 724 LYM10potato|gb157.2|BQ516058 2231 249 91.3 blastp H144 725 LYM10prunus|gb167|BU039566 2232 249 92.8 blastp H145 726 LYM10prunus|gb167|BU046783 2233 249 87 blastp H146 727 LYM10radish|gb164|EV526354 2234 249 91.3 tblastn H147 728 LYM10radish|gb164|EV528390 2235 249 91.3 blastp H148 729 LYM10radish|gb164|EV536273 2236 249 91.3 blastp H149 730 LYM10radish|gb164|EV545751 2237 249 91.3 tblastn H150 731 LYM10radish|gb164|EV548721 2238 249 91.3 blastp H151 732 LYM10radish|gb164|EV550488 2239 249 91.3 blastp H152 733 LYM10radish|gb164|EV567397 2240 249 85.5 blastp H153 734 LYM10radish|gb164|EW713425 2241 249 89.9 blastp H154 735 LYM10radish|gb164|FD570559 2242 249 89.9 blastp H155 736 LYM10rice|gb170|OS06G44374 2243 249 95.7 blastp H268 737 LYM10rose|gb157.2|BI978198 2244 249 91.3 tblastn H157 738 LYM10rose|gb157.2|EC589842 2245 249 92.75 tblastn H158 739 LYM10safflower|gb162|EL393855 2246 249 88.41 tblastn H159 740 LYM10safflower|gb162|EL511136 2247 249 89.9 blastp H160 741 LYM10senecio|gb170|CO553399 2248 249 88.4 blastp H269 742 LYM10sesame|gb157.2|BU669069 2249 249 91.3 tblastn H161 743 LYM10 solanum2250 249 89.9 blastp H270 phureja|09v1|SPHAI483617 744 LYM10 solanum2251 249 91.3 blastp H271 phureja|09v1|SPHBG127130 745 LYM10sorghum|09v1|SB04G005280 2252 249 98.6 blastp H272 746 LYM10sorghum|09v1|SB10G026000 2253 249 97.1 blastp H273 747 LYM10soybean|gb168|AA660461 2254 249 94.2 blastp H164 748 LYM10soybean|gb168|AW472512 2255 249 92.8 blastp H165 749 LYM10soybean|gb168|BU544187 2256 249 94.2 blastp H166 750 LYM10spikemoss|gb165|DN838422 2257 249 85.51 tblastn H167 751 LYM10spruce|gb162|CO216979 2258 249 91.3 blastp H168 752 LYM10spruce|gb162|CO217020 2259 249 91.3 blastp H169 753 LYM10spurge|gb161|DV112655 2260 249 84.1 blastp H170 754 LYM10spurge|gb161|DV120263 2261 249 86.5 blastp H171 755 LYM10strawberry|gb164|CO380171 2262 249 91.3 tblastn H172 756 LYM10strawberry|gb164|EX664646 2263 249 92.8 blastp H173 757 LYM10sugarcane|gb157.3|CA072778 2264 249 97.1 blastp H274 758 LYM10sugarcane|gb157.3|CA087927 2265 249 98.6 blastp H275 759 LYM10sugarcane|gb157.3|CA103056 2266 249 98.6 blastp H276 760 LYM10sunflower|gb162|BU015373 2267 249 89.86 tblastn H177 761 LYM10sunflower|gb162|CD849625 2268 249 88.4 blastp H178 762 LYM10sunflower|gb162|CD851122 2269 249 88.41 tblastn H179 763 LYM10switchgrass|gb167|DN145554 2270 249 98.6 blastp H180 764 LYM10switchgrass|gb167|FE633347 2271 249 97.1 blastp H181 765 LYM10switchgrass|gb167|FE639131 2272 249 98.6 blastp H182 766 LYM10switchgrass|gb167|FL720694 2273 249 95.7 blastp H183 767 LYM10tamarix|gb166|EG968743 2274 249 85.5 blastp H184 768 LYM10tamarix|gb166|EG969152 2275 249 88.4 blastp H185 769 LYM10tea|gb171|FF682807 2276 249 95.7 blastp H277 770 LYM10thellungiella|gb167|BI698898 2277 249 91.3 blastp H186 771 LYM10thellungiella|gb167|EC599088 2278 249 91.3 blastp H187 772 LYM10tobacco|gb162|CV020564 2279 249 81.8 blastp H188 773 LYM10tobacco|gb162|CV021149 2280 249 80.8 blastp H189 774 LYM10tobacco|gb162|CV021577 2281 249 91.3 tblastn H190 775 LYM10tobacco|gb162|EB426093 2282 249 91.3 tblastn H191 776 LYM10tobacco|gb162|EB447225 2283 249 89.9 blastp H192 777 LYM10tomato|09v1|AI483617 2284 249 89.9 blastp H278 778 LYM10tomato|09v1|BG127130 2285 249 91.3 tblastn H279 779 LYM10triphysaria|gb164|EX988147 2286 249 81.6 blastp H195 780 LYM10walnuts|gb166|CB304079 2287 249 98.6 blastp H196 781 LYM10wheat|gb164|BE423226 2288 249 100 tblastn H197 782 LYM10wheat|gb164|BE423858 2289 249 100 tblastn H198 783 LYM10wheat|gb164|BE445139 2290 249 98.55 tblastn H199 784 LYM10wheat|gb164|BE604834 2291 249 98.55 tblastn H200 785 LYM10wheat|gb164|BF473482 2292 249 100 tblastn H201 786 LYM10wheat|gb164|BF474814 2293 249 98.55 tblastn H202 787 LYM10wheat|gb164|BI479895 2294 249 98.55 tblastn H203 788 LYM10wheat|gb164|CA619357 2295 249 86.96 tblastn H204 789 LYM10wheat|gb164|CA619965 2296 249 91.3 tblastn H205 790 LYM10wheat|gb164|CA627315 2297 249 83.8 blastp H206 791 LYM10wheat|gb164|DR737205 2298 249 85.51 tblastn H207 792 LYM13 H3brachypodium|09v1|GT794488 2299 251 80.6 blastp 793 LYM13 H4maize|gb170|T12684 2300 251 84.5 blastp 794 LYM13 H5sorghum|09v1|SB01G049950 2301 251 84.5 blastp 795 LYM13 H3switchgrass|gb167|FE634401 2302 251 84.53 tblastn 796 LYM14 H1aquilegia|gb157.3|DR927713 2303 252 81.1 blastp 797 LYM14 arabidopsis2304 252 80.7 blastp H31 lyrata|09v1|JGIAL009556 798 LYM14 arabidopsis2305 252 80.4 blastp H32 lyrata|09v1|JGIAL020254 799 LYM14 H2arabidopsis|gb165|AT3G11320 2306 252 80.4 blastp 800 LYM14 H3arabidopsis|gb165|AT5G05820 2307 252 80.4 blastp 801 LYM14 H4artemisia|gb164|EY034514 2308 252 81.7 blastp 802 LYM14brachypodium|09v1|GT762844 2309 252 96 blastp H33 803 LYM14 H7canola|gb161|DY024685 2310 252 81.1 blastp 804 LYM14cassava|09v1|CK650018 2311 252 80.1 blastp H34 805 LYM14castorbean|09v1|EG659029 2312 252 80.43 tblastn H35 806 LYM14 H8centaurea|gb166|EH712821 2313 252 80.1 blastp 807 LYM14cichorium|gb171|EH688253 2314 252 80.7 blastp H36 808 LYM14cotton|gb164|AA659984 2315 252 80.43 tblastn H11 809 LYM14cucumber|09v1|DN910737 2316 252 80.75 tblastn H37 810 LYM14ginger|gb164|DY358976 2317 252 83.3 blastp H12 811 LYM14iceplant|gb164|AI822835 2318 252 80.75 tblastn H13 812 LYM14lettuce|gb157.2|DW158376 2319 252 82.3 tblastn H14 813 LYM14leymus|gb166|CD809180 2320 252 95 blastp H15 814 LYM14maize|gb170|AI783260 2321 252 93.8 blastp H38 815 LYM14maize|gb170|AI941675 2322 252 95.1 blastp H39 816 LYM14melon|gb165|AM713763 2323 252 80.5 tblastn H18 817 LYM14monkeyflower|09v1|GO959633 2324 252 80.12 tblastn H40 818 LYM14monkeyflower|09v1|GR111000 2325 252 80.12 tblastn H41 819 LYM14papaya|gb165|EX261125 2326 252 81.1 blastp H19 820 LYM14radish|gb164|EW723681 2327 252 81.37 tblastn H20 821 LYM14 solanum 2328252 80.1 blastp H42 phureja|09v1|SPHBG628013 822 LYM14sorghum|09v1|SB01G038730 2329 252 96 blastp H43 823 LYM14sorghum|09v1|SB02G044050 2330 252 86 blastp H44 824 LYM14soybean|gb168|AW560935 2331 252 80.1 blastp H23 825 LYM14spikemoss|gb165|FE434307 2332 252 81.06 tblastn H25 826 LYM14sugarcane|gb157.3|CA079818 2333 252 84.2 blastp H45 827 LYM14sugarcane|gb157.3|CA150518 2334 252 93.85 tblastn H46 828 LYM14sunflower|gb162|EL484937 2335 252 80.75 tblastn H29 829 LYM14switchgrass|gb167|DN143407 2336 252 95.4 blastp H30 830 LYM14tomato|09v1|BG628013 2337 252 80.1 blastp H47 831 LYM14wheat|gb164|BE416003 2338 252 83.6 blastp H31 832 LYM15 H4brachypodium|09v1|DV476162 2339 253 80.2 blastp 833 LYM15 H2pseudoroegneria|gb167| 2340 253 82 blastp FF343970 834 LYM15 H3wheat|gb164|BE213295 2341 253 81.4 blastp 835 LYM15 H4wheat|gb164|BE496833 2342 253 81.4 blastp 836 LYM16 H9barley|gb157SOLEXA| 2343 254 90.9 blastp BE421507 837 LYM16brachypodium|09v1|DV475217 2344 254 92.7 blastp H10 838 LYM16 H3fescue|gb161|DT691110 2345 254 93.9 blastp 839 LYM16lolium|09v1|AU246876 2346 254 84.1 blastp H11 840 LYD199maize|gb170|BI423687 2347 254 82.9 blastp 841 LYM16maize|gb170|LLFL254633 2348 254 81.1 tblastn H12 842 LYM16 H5pseudoroegneria|gb167| 2349 254 92.1 blastp FF355494 843 LYM16 H6rye|gb164|BE494944 2350 254 90.24 tblastn 844 LYM16 H7wheat|gb164|BE216981 2351 254 91.5 blastp 845 LYM16 H8wheat|gb164|BE416071 2352 254 90.9 blastp 846 LYM16 H9wheat|gb164|BE418113 2353 254 91.5 blastp 847 LYM17 H6barley|gb157SOLEXA| 2354 255 83.3 blastp BE602651 848 LYM17 H7sugarcane|gb157.3|CA152022 2355 255 80.3 blastp 849 LYM17 H3wheat|gb164|BE406565 2356 255 85.6 blastp 850 LYM17 H4wheat|gb164|BE429209 2357 255 85.6 blastp 851 LYM17 H5wheat|gb164|BE490714 2358 255 86.4 blastp 852 LYM17 H6wheat|gb164|BQ803198 2359 255 85.6 blastp 853 LYM19 barley|gb157SOLEXA|2360 256 86 blastp H10 AL506367 854 LYM19 brachypodium|09v1|DV4763392361 256 87.2 blastp H11 855 LYM19 H3 leymus|gb166|EG387247 2362 25684.8 blastp 856 LYM19 H5 pseudoroegneria|gb167| 2363 256 86.9 blastpFF352256 857 LYM19 sorghum|09v1|SB05G009990 2364 256 82.6 blastp H12 858LYM19 H7 switchgrass|gb167|FE603507 2365 256 83.6 blastp 859 LYM19 H8wheat|gb164|BE398692 2366 256 82.7 blastp 860 LYM19 H9wheat|gb164|BE585979 2367 256 86.28 tblastn 861 LYM19wheat|gb164|BU672325 2368 256 81.4 blastp H10 862 LYM20 H9barley|gb157SOLEXA| 2369 257 86.3 blastp AL450927 863 LYM20brachypodium|09v1|DV479896 2370 257 89.1 blastp H10 864 LYM20castorbean|09v1|XM002519056 2371 257 80 blastp H11 865 LYM20maize|gb170|AI857236 2372 257 90.1 blastp H12 866 LYM20 H5pseudoroegneria|gb167| 2373 257 89 blastp FF343142 867 LYM20sorghum|09v1|SB01G009140 2374 257 89.7 blastp H13 868 LYM20sugarcane|gb157.3|CA072511 2375 257 83.9 blastp H14 869 LYM20 H8switchgrass|gb167|FE654910 2376 257 84.5 blastp 870 LYM20 H9wheat|gb164|BE411982 2377 257 88.6 blastp 871 LYM21 H1banana|gb167|FF557436 2378 258 80.9 blastp 872 LYM21 H2banana|gb167|FF559448 2379 258 80.9 blastp 873 LYM21 barley|gb157SOLEXA|2380 258 88.2 blastp H27 BE437461 874 LYM21 brachypodium|09v1|DV4881502381 258 95.5 blastp H28 875 LYM21 brachypodium|09v1|GT760558 2382 25897.3 blastp H29 876 LYM21 H5 cenchrus|gb166|EB655115 2383 258 91.8blastp 877 LYM21 H6 fescue|gb161|DT680631 2384 258 90 blastp 878 LYM21H7 kiwi|gb166|FG405276 2385 258 81.8 blastp 879 LYM21 H8leymus|gb166|CN465770 2386 258 88.2 blastp 880 LYM21lolium|09v1|AU250288 2387 258 90 blastp H30 881 LYM21 H9lovegrass|gb167|DN480337 2388 258 92.7 blastp 882 LYM21maize|gb170|AI586459 2389 258 93.6 blastp H31 883 LYM21millet|09v1|EVO454PM000432 2390 258 95.5 blastp H32 884 LYM21millet|09v1|EVO454PM000947 2391 258 91.8 blastp H33 885 LYM21pineapple|gb157.2|CO731607 2392 258 82.73 tblastn H12 886 LYM21rice|gb170|OS02G47320 2393 258 87.27 tblastn H34 887 LYM21sorghum|09v1|SB02G006170 2394 258 93.6 blastp H35 888 LYM21sorghum|09v1|SB06G027500 2395 258 95.5 blastp H36 889 LYM21sugarcane|gb157.3|BQ529660 2396 258 93.6 blastp H37 890 LYM21sugarcane|gb157.3|BQ535381 2397 258 92.7 blastp H38 891 LYM21sugarcane|gb157.3|CA118830 2398 258 87.3 blastp H39 892 LYM21switchgrass|gb167|DN151016 2399 258 93.6 blastp H19 893 LYM21switchgrass|gb167|FL722429 2400 258 94.5 blastp H20 894 LYM21switchgrass|gb167|FL936988 2401 258 95.5 blastp H21 895 LYM21tobacco|gb162|AM791579 2402 258 88.2 blastp H22 896 LYM21wheat|gb164|BE352632 2403 258 89.1 blastp H23 897 LYM21wheat|gb164|BE402792 2404 258 89.1 blastp H24 898 LYM21wheat|gb164|BE492575 2405 258 89.09 tblastn H25 899 LYM21wheat|gb164|CA484575 2406 258 94.5 blastp H26 900 LYM21wheat|gb164|CA616609 2407 258 92.73 tblastn H27 901 LYM24 H1fescue|gb161|DT681171 2408 261 80.61 tblastn 902 LYM24 H2leymus|gb166|CD808623 2409 261 80.5 blastp 903 LYM24 H8maize|gb170|AI621440 2410 261 81 blastp 904 LYM24 H9pseudoroegneria|gb167| 2411 261 80 blastp FF349814 905 LYM24sorghum|09v1|SB03G044280 2412 261 83.1 blastp H10 906 LYM24sugarcane|gb157.3|CA072633 2413 261 82.6 blastp H11 907 LYM24 H6switchgrass|gb167|DN144637 2414 261 84.6 blastp 908 LYM24 H7switchgrass|gb167|DN145452 2415 261 85.6 blastp 909 LYM24 H8wheat|gb164|BE425900 2416 261 80 tblastn 910 LYM26 H1wheat|gb164|BE398903 2417 262 88.6 blastp 911 LYM30 H5brachypodium|09v1|SRR031799S0073966 2418 263 86.5 blastp 912 LYM30 H6maize|gb170|AW520185 2419 263 85.8 blastp 913 LYM30 H7maize|gb170|AW927689 2420 263 85 blastp 914 LYM30 H8rice|gb170|OS11G02580 2421 263 99.2 blastp 915 LYM30 H9rice|gb170|OS12G02510 2422 263 87.7 blastp 916 LYM30sorghum|09v1|SB05G001250 2423 263 86.1 blastp H10 917 LYM30 H5switchgrass|gb167|FL796240 2424 263 80.16 tblastn 918 LYM31 H1rice|gb170|OS12G02710 2425 264 97.9 blastp 919 LYM35 H5brachypodium|09v1|SRR031798S0189278 2426 267 80 blastp 920 LYM35 H6maize|gb170|BM416880 2427 267 89.7 blastp 921 LYM35 H7sorghum|09v1|SB06G031730 2428 267 86.7 blastp 922 LYM35 H8sugarcane|gb157.3|CA105471 2429 267 87.5 blastp 923 LYM35 H4switchgrass|gb167|FL939819 2430 267 89.9 blastp 924 LYM35 H5wheat|gb164|BE500504 2431 267 86.1 blastp 925 LYM42 H0rice|gb170|OS01G41120 2432 273 96.7 blastp 925 LYM42 H0rice|gb170|OS01G41120 2432 439 99.83 tblastn 926 LYM43 H1rice|gb170|OS12G02800 2433 274 91.4 blastp 927 LYM52 H1 b 2434 277 94.5blastp rapa|gb162|EX068270 928 LYM52 H2 fescue|gb161|CK802823 2435 27784.4 blastp 929 LYM52 H3 leymus|gb166|EG379466 2436 277 96.3 blastp 930LYM52 maize|gb170|BE130094 2437 277 80 blastp H10 931 LYM52maize|gb170|LLBE056010 2438 277 81 blastp H11 932 LYM52rice|gb170|OS04G51792 2439 277 81.4 blastp H12 933 LYM52sorghum|09v1|SB06G027870 2440 277 82.5 blastp H13 934 LYM52sugarcane|gb157.3|AA577629 2441 277 84.47 tblastn H14 935 LYM52 H8switchgrass|gb167|DN147335 2442 277 82.65 tblastn 936 LYM52 H9wheat|gb164|BG909259 2443 277 94.5 blastp 937 LYM52 wheat|gb164|BG9094932444 277 95.1 blastp H10 938 LYM56 H9brachypodium|09v1|SRR031795S0049724 2445 279 85.9 blastp 939 LYM56maize|gb170|AI711954 2446 279 80.14 tblastn H10 940 LYM56 H2pseudoroegneria|gb167| 2447 279 87.9 blastp FF341776 941 LYM56rice|gb170|OS03G45720 2448 279 80.1 blastp H11 942 LYM56sorghum|09v1|SB01G012840 2449 279 81 blastp H12 943 LYM56sugarcane|gb157.3|BQ533995 2450 279 80.14 tblastn H13 944 LYM56 H6switchgrass|gb167|FE631693 2451 279 84.5 blastp 945 LYM56 H7switchgrass|gb167|FL782747 2452 279 83.1 blastp 946 LYM56 H8wheat|gb164|BE404207 2453 279 88.7 blastp 947 LYM56 H9wheat|gb164|CD912963 2454 279 87.8 blastp 948 LYM57 H0brachypodium|09v1|DV475724 2455 280 81.1 blastp 949 LYM62 H1sorghum|09v1|SB10G012150 2456 282 88.9 blastp 950 LYM66 H1wheat|gb164|BE403932 2457 283 83 blastp 950 LYM66 H1wheat|gb164|BE403932 2457 440 83 blastp 951 LYM66 H2wheat|gb164|BE405409 2458 283 90.4 blastp 951 LYM66 H2wheat|gb164|BE405409 2458 440 90.4 blastp 952 LYM66 H3wheat|gb164|CA600263 2459 283 90.1 blastp 952 LYM66 H3wheat|gb164|CA600263 2459 440 90.1 blastp 953 LYM69 H0rice|gb170|OS07G42520 2460 286 98.3 blastp 954 LYM73 H6brachypodium|09v1|DV481090 2461 287 95.8 blastp 955 LYM73 H7maize|gb170|AW256155 2462 287 93.7 blastp 956 LYM73 H8sorghum|09v1|SB07G004300 2463 287 94.3 blastp 957 LYM73 H9sugarcane|gb157.3|CA117425 2464 287 94.3 blastp 958 LYM73 H5switchgrass|gb167|DN145973 2465 287 94.6 blastp 959 LYM73 H6wheat|gb164|AF289257S1 2466 287 92.67 tblastn 960 LYM79 H3brachypodium|09v1|SRR031800S0005207 2467 289 83.8 blastp 961 LYM79 H4millet|09v1|EVO454PM011117 2468 441 82.72 tblastn 962 LYM79 H5sorghum|09v1|SB10G012140 2469 289 93 blastp 962 LYM79 H5sorghum|09v1|SB10G012140 2469 441 93.75 tblastn 963 LYM79 H1switchgrass|gb167|FE598528 2470 289 90.6 blastp 963 LYM79 H1switchgrass|gb167|FE598528 2470 441 91.1 tblastn 964 LYM79 H2switchgrass|gb167|FL957870 2471 441 86.6 tblastn 965 LYM79 H3wheat|gb164|BE590518 2472 289 80 blastp 965 LYM79 H3wheat|gb164|BE590518 2472 441 83.33 tblastn 966 LYM82 H1banana|gb167|FF561962 2473 290 82.1 blastp 967 LYM82brachypodium|09v1|GT816645 2474 290 94.1 blastp H12 968 LYM82 H2leymus|gb166|EG384073 2475 290 97.9 blastp 969 LYM82maize|gb170|AW181152 2476 290 90.6 blastp H13 970 LYM82 H4melon|gb165|AM718213 2477 290 80.21 tblastn 971 LYM82millet|09v1|EVO454PM002754 2478 290 82.99 tblastn H14 972 LYM82 H5pseudoroegneria|gb167| 2479 290 99 blastp FF352234 973 LYM82rice|gb170|OS06G04460 2480 290 91 blastp H15 974 LYM82sorghum|09v1|SB10G002420 2481 290 90.3 blastp H16 975 LYM82 H8soybean|gb168|CA921223 2482 290 80.21 tblastn 976 LYM82sugarcane|gb157.3|BU102729 2483 290 90.3 blastp H17 977 LYM82switchgrass|gb167|FL744837 2484 290 89.6 blastp H10 978 LYM82wheat|gb164|BE403842 2485 290 99 blastp H11 979 LYM82wheat|gb164|CA660788 2486 290 99 blastp H12 980 LYM83 H8brachypodium|09v1|SRR031797S0009670 2487 291 86.5 blastp 980 LYM83 H8brachypodium|09v1|SRR031797S0009670 2487 442 86.1 blastp 981 LYM83 H9lolium|09v1|ES699086 2488 291 84.84 tblastn 981 LYM83 H9lolium|09v1|ES699086 2488 442 84.43 tblastn 982 LYM83maize|gb170|AI665347 2489 291 82.4 blastp H10 982 LYM83maize|gb170|AI665347 2489 442 82.4 blastp H10 983 LYM83 H3pseudoroegneria|gb167| 2490 291 97.5 blastp FF354990 983 LYM83 H3pseudoroegneria|gb167| 2490 442 97.1 blastp FF354990 984 LYM83rice|gb170|OS05G45300 2491 291 81.6 blastp H11 984 LYM83rice|gb170|OS05G45300 2491 442 81.1 blastp H11 985 LYM83sorghum|09v1|SB09G026370 2492 291 82 blastp H12 985 LYM83sorghum|09v1|SB09G026370 2492 442 81.6 blastp H12 986 LYM83 H6switchgrass|gb167|DN149383 2493 291 84 blastp 986 LYM83 H6switchgrass|gb167|DN149383 2493 442 83.6 blastp 987 LYM83 H7wheat|gb164|BE516715 2494 291 94.7 blastp 987 LYM83 H7wheat|gb164|BE516715 2494 442 94.3 blastp 988 LYM83 H8wheat|gb164|BF428688 2495 291 95.1 blastp 988 LYM83 H8wheat|gb164|BF428688 2495 442 94.7 blastp 989 LYM84 H8brachypodium|09v1|SRR031795S0021840 2496 292 92.8 blastp 990 LYM84 H9maize|gb170|AW282161 2497 292 82.8 blastp 991 LYM84maize|gb170|LLDQ245778 2498 292 98.7 blastp H10 992 LYM84 H4pseudoroegneria|gb167| 2499 292 98.3 blastp FF355744 993 LYM84rice|gb170|OS03G41612 2500 292 84.58 tblastn H11 994 LYM84sorghum|09v1|SB01G014640 2501 292 82.9 blastp H12 995 LYM84 H7switchgrass|gb167|FE652995 2502 292 81.3 blastp 996 LYM84 H8wheat|gb164|BE417697 2503 292 95.1 blastp 997 LYM88 H0 arabidopsis 2504294 91.5 blastp lyrata|09v1|JGIAL014996 998 LYM89 H5 arabidopsis 2505295 86.36 tblastn lyrata|09v1|JGIAL031299 999 LYM89 H2canola|gb161|CD812018 2506 295 81.8 blastp 1000 LYM89 H3canola|gb161|CD821897 2507 295 81.8 blastp 1001 LYM89 H4radish|gb164|EW732798 2508 295 81.65 tblastn 1002 LYM89 H5radish|gb164|EX749702 2509 295 80.7 blastp 1003 LYM90 H3brachypodium|09v1|DV488904 2510 296 83.2 blastp 1004 LYM90 H2wheat|gb164|BQ242151 2511 296 94.6 blastp 1005 LYM90 H3wheat|gb164|BQ244922 2512 296 94.6 blastp 1006 LYM91 H1rye|gb164|BE494176 2513 297 82.5 blastp 1007 LYM91 H2wheat|gb164|BE400659 2514 297 85.4 blastp 1008 LYM91 H3wheat|gb164|CA593112 2515 297 86.27 tblastn 1009 LYM93 H1wheat|gb164|BE401535 2516 298 93.6 blastp 1010 LYM93 H2wheat|gb164|BE418047 2517 298 93.6 blastp 1011 LYM93 H3wheat|gb164|CA624071 2518 298 84.6 blastp 1012 LYM93 H4wheat|gb164|CA678405 2519 298 94.55 tblastn 1013 LYM93 H5wheat|gb164|CJ920171 2520 298 88.7 blastp 1014 LYM99 H2brachypodium|09v1|DV482533 2521 299 86.8 blastp 1015 LYM99 H2wheat|gb164|AL818990 2522 299 94.12 tblastn 1016 LYM100wheat|gb164|BE399036 2523 301 89.5 blastp H1 1017 LYM103sorghum|09v1|SB03G004410 2524 303 89.69 tblastn H2 1018 LYM103sugarcane|gb157.3|CA078686 2525 303 89.69 tblastn H3 1019 LYM103switchgrass|gb167|FL877864 2526 303 87 blastp H2 1020 LYM105barley|gb157SOLEXA| 2527 304 90.9 blastp H5 BQ461657 1021 LYM105pseudoroegneria|gb167| 2528 304 90.5 blastp H2 FF366339 1022 LYM105wheat|gb164|BE405330 2529 304 90 blastp H3 1023 LYM105wheat|gb164|BE637936 2530 304 91.8 blastp H4 1024 LYM105wheat|gb164|BQ743875 2531 304 89.4 blastp H5 1025 LYM106brachypodium|09v1|DV476632 2532 305 80.7 blastp H8 1026 LYM106maize|gb170|LLDQ245927 2533 305 97.9 blastp H9 1027 LYM106pseudoroegneria|gb167| 2534 305 96.5 blastp H3 FF347837 1028 LYM106rye|gb164|BE586535 2535 305 90.3 blastp H4 1029 LYM106spruce|gb162|DR543563 2536 305 84.72 tblastn H5 1030 LYM106wheat|gb164|BE443195 2537 305 96.5 blastp H6 1031 LYM106wheat|gb164|BE445264 2538 305 97.9 blastp H7 1032 LYM106wheat|gb164|BF485098 2539 305 97.2 blastp H8 1033 LYM110sugarcane|gb157.3|CA204413 2540 306 84.3 tblastn H1 1034 LYM111brachypodium|09v1|GT765731 2541 307 80.96 tblastn H7 1035 LYM111cenchrus|gb166|EB657665 2542 307 87.6 blastp H1 1036 LYM111maize|gb170|AI941545 2543 307 89.9 blastp H8 1037 LYM111rice|gb170|OS01G57066 2544 307 81.5 blastp H9 1038 LYM111sorghum|09v1|SB03G036350 2545 307 91.5 blastp H10 1039 LYM111sorghum|09v1|SB05G023720 2546 307 93.1 tblastn H11 1040 LYM111sugarcane|gb157.3|CA072460 2547 307 89.38 tblastn H12 1041 LYM111switchgrass|gb167|FL711377 2548 307 90.8 blastp H7 1042 LYM119sorghum|09v1|SB05G003680 2549 308 93.8 blastp H1 1043 LYM122brachypodium|09v1|DV469739 2550 310 84.5 blastp H1 1044 LYM122pseudoroegneria|gb167| 2551 310 82.53 tblastn H1 FF350527 1045 LYM129brachypodium|09v1|SRR031795S0005798 2552 315 80.4 blastp H2 1046 LYM129maize|gb170|BQ486269 2553 315 82.8 blastp H3 1047 LYM129sorghum|09v1|SB03G044510 2554 315 81.6 blastp H4 1048 LYM129switchgrass|gb167|FE643628 2555 315 80.6 blastp H2 1049 LYM130leymus|gb166|EG377985 2556 316 80.2 blastp H1 1050 LYM130rice|gb170|OS05G04380 2557 316 99.4 blastp H2 1051 LYM130wheat|gb164|BE414767 2558 316 80.8 blastp H2 1052 LYM131aquilegia|gb157.3|DR917618 2559 317 81.2 blastp H1 1053 LYM131barley|gb157SOLEXA| 2560 317 83 blastp H13 AL450948 1054 LYM131brachypodium|09v1|DV479902 2561 317 85.3 blastp H14 1055 LYM131maize|gb170|AI861327 2562 317 90.8 blastp H15 1056 LYM131maize|gb170|AW129826 2563 317 82.8 blastp H16 1057 LYM131maize|gb170|AW453172 2564 317 91.7 blastp H17 1058 LYM131rice|gb170|OS08G12750 2565 317 85.1 blastp H18 1059 LYM131sorghum|09v1|SB06G027970 2566 317 91.5 blastp H19 1060 LYM131sorghum|09v1|SB07G006320 2567 317 81 blastp H20 1061 LYM131sugarcane|gb157.3|CA068895 2568 317 91.5 blastp H21 1062 LYM131switchgrass|gb167|FE607026 2569 317 81.7 blastp H11 1063 LYM131switchgrass|gb167|FL708944 2570 317 91.49 tblastn H12 1064 LYM131wheat|gb164|BE412257 2571 317 83.7 blastp H13 1065 LYM134rice|gb170|OS04G56990 2572 319 98.8 blastp H0 1066 LYM137amborella|gb166|CK758151 2573 321 85.1 blastp H2 1067 LYM137antirrhinum|gb166|AJ788115 2574 321 83.7 blastp H3 1068 LYM137antirrhinum|gb166|AJ791024 2575 321 83 blastp H4 1069 LYM137antirrhinum|gb166|AJ793144 2576 321 83.01 tblastn H5 1070 LYM137apple|gb171|CN445333 2577 321 81 blastp H217 1071 LYM137apple|gb171|CN489019 2578 321 82.4 blastp H218 1072 LYM137apple|gb171|CN491888 2579 321 81.8 blastp H219 1073 LYM137aquilegia|gb157.3|DT729599 2580 321 82.7 blastp H10 1074 LYM137arabidopsis 2581 321 81.8 blastp H220 lyrata|09v1|BQ834082 1075 LYM137arabidopsis 2582 321 80.5 blastp H221 lyrata|09v1|BQ834260 1076 LYM137arabidopsis 2583 321 80.5 blastp H222 lyrata|09v1|JGIAL015196 1077LYM137 arabidopsis|gb165|AT3G55280 2584 321 81.2 blastp H11 1078 LYM137artemisia|gb164|EY035831 2585 321 85 blastp H12 1079 LYM137avocado|gb164|CO995706 2586 321 85.3 blastp H13 1080 LYM137avocado|gb164|CV460574 2587 321 84.6 blastp H14 1081 LYM137 b 2588 32183.8 blastp H15 juncea|gb164|EVGN00185312102498 1082 LYM137 b 2589 32181.2 blastp H16 juncea|gb164|EVGN00317014862029 1083 LYM137 b 2590 32181.2 blastp H17 juncea|gb164|EVGN01375409582897 1084 LYM137 b 2591 32181.2 blastp H223 nigra|09v1|GT069407 1085 LYM137 b 2592 321 81.2 blastpH18 oleracea|gb161|AM392244 1086 LYM137 b 2593 321 83.8 blastp H19oleracea|gb161|DY014383 1087 LYM137 b 2594 321 83.8 blastp H20oleracea|gb161|DY023491 1088 LYM137 b 2595 321 81.2 blastp H21oleracea|gb161|DY023494 1089 LYM137 b 2596 321 81.2 blastp H22oleracea|gb161|DY027443 1090 LYM137 b 2597 321 80.5 blastp H23oleracea|gb161|EE535717 1091 LYM137 b 2598 321 83.77 tblastn H24rapa|gb162|BG543640 1092 LYM137 b 2599 321 80.5 blastp H25rapa|gb162|BQ791808 1093 LYM137 b 2600 321 81.2 blastp H26rapa|gb162|CA991997 1094 LYM137 b 2601 321 81.2 blastp H27rapa|gb162|CV432555 1095 LYM137 b 2602 321 81.2 blastp H28rapa|gb162|CV432912 1096 LYM137 b 2603 321 83.8 blastp H29rapa|gb162|CV432918 1097 LYM137 b 2604 321 81.2 blastp H30rapa|gb162|CX267185 1098 LYM137 b 2605 321 81.2 blastp H31rapa|gb162|CX271342 1099 LYM137 banana|gb167|DN239514 2606 321 85.7blastp H32 1100 LYM137 banana|gb167|ES431662 2607 321 86.4 blastp H331101 LYM137 banana|gb167|FF558102 2608 321 85.7 blastp H34 1102 LYM137banana|gb167|FF558729 2609 321 86.4 blastp H35 1103 LYM137banana|gb167|FF560801 2610 321 85.7 blastp H36 1104 LYM137banana|gb167|FL657344 2611 321 85.8 blastp H37 1105 LYM137basilicum|gb157.3|DY342616 2612 321 80.5 blastp H38 1106 LYM137bean|gb167|CA897728 2613 321 85 blastp H39 1107 LYM137bean|gb167|CA897730 2614 321 83.1 blastp H40 1108 LYM137beet|gb162|BF011189 2615 321 82.5 blastp H41 1109 LYM137beet|gb162|BI096284 2616 321 84.4 blastp H42 1110 LYM137brachypodium|09v1|DV476457 2617 321 96.1 blastp H224 1111 LYM137brachypodium|09v1|DV489152 2618 321 96.1 blastp H225 1112 LYM137cacao|gb167|CA795798 2619 321 83.7 blastp H45 1113 LYM137cacao|gb167|CU476798 2620 321 83.8 blastp H46 1114 LYM137canola|gb161|CD811640 2621 321 83.8 blastp H47 1115 LYM137canola|gb161|CD812285 2622 321 81.2 blastp H48 1116 LYM137canola|gb161|CD812312 2623 321 81.2 blastp H49 1117 LYM137canola|gb161|CD812501 2624 321 81.2 blastp H50 1118 LYM137canola|gb161|CD815420 2625 321 81.2 blastp H51 1119 LYM137canola|gb161|CD816902 2626 321 81.2 blastp H52 1120 LYM137canola|gb161|CD817591 2627 321 81.2 blastp H53 1121 LYM137canola|gb161|CD821663 2628 321 83.8 blastp H54 1122 LYM137canola|gb161|CN726029 2629 321 83.8 blastp H55 1123 LYM137canola|gb161|CN731028 2630 321 81.2 blastp H56 1124 LYM137canola|gb161|EE479368 2631 321 83.8 blastp H57 1125 LYM137canola|gb161|H07535 2632 321 83.8 blastp H58 1126 LYM137cassava|09v1|CK643771 2633 321 83.1 blastp H226 1127 LYM137cassava|09v1|CK647492 2634 321 83.8 blastp H227 1128 LYM137cassava|09v1|DV455355 2635 321 81.8 blastp H228 1129 LYM137castorbean|09v1|EG700188 2636 321 85 blastp H229 1130 LYM137castorbean|09v1|XM002531924 2637 321 84.9 blastp H230 1131 LYM137catharanthus|gb166|EG556131 2638 321 82.6 blastp H63 1132 LYM137catharanthus|gb166|EG557604 2639 321 82.6 blastp H64 1133 LYM137cenchrus|gb166|EB652612 2640 321 93.4 blastp H65 1134 LYM137centaurea|gb166|EH715158 2641 321 83 blastp H66 1135 LYM137centaurea|gb166|EH737696 2642 321 84.3 blastp H67 1136 LYM137centaurea|gb166|EH746709 2643 321 82.5 blastp H68 1137 LYM137chestnut|gb170|SRR006295S0004667 2644 321 83.8 blastp H231 1138 LYM137chestnut|gb170|SRR006295S0010167 2645 321 83.1 blastp H232 1139 LYM137chickpea|09v2|FE669244 2646 321 85.6 blastp H233 1140 LYM137chickpea|09v2|FE671615 2647 321 85.6 blastp H234 1141 LYM137cichorium|gb171|DT210912 2648 321 84.3 blastp H235 1142 LYM137cichorium|gb171|EH681883 2649 321 84.4 blastp H236 1143 LYM137cichorium|gb171|EH696050 2650 321 83.8 blastp H237 1144 LYM137citrus|gb166|CB610578 2651 321 83.7 blastp H72 1145 LYM137citrus|gb166|CN183415 2652 321 82.9 blastp H73 1146 LYM137coffea|gb157.2|DV663668 2653 321 85 blastp H74 1147 LYM137cotton|gb164|AI728522 2654 321 84.3 blastp H75 1148 LYM137cotton|gb164|AI729531 2655 321 85 blastp H76 1149 LYM137cotton|gb164|BE055719 2656 321 83 blastp H77 1150 LYM137cotton|gb164|BF269641 2657 321 84.3 blastp H78 1151 LYM137cotton|gb164|BG441496 2658 321 81.8 blastp H79 1152 LYM137cowpea|gb166|BE336250 2659 321 83.9 blastp H80 1153 LYM137cowpea|gb166|FF382348 2660 321 85.1 blastp H81 1154 LYM137cowpea|gb166|FF391267 2661 321 86.9 blastp H82 1155 LYM137cryptomeria|gb166|BP176442 2662 321 80.5 blastp H83 1156 LYM137cryptomeria|gb166|BW996322 2663 321 81.2 blastp H84 1157 LYM137cucumber|09v1|BGI454H0165031 2664 321 81.6 blastp H238 1158 LYM137cucumber|09v1|CK085893 2665 321 83.7 blastp H239 1159 LYM137cucumber|09v1|DV632825 2666 321 85 blastp H240 1160 LYM137cynara|gb167|GE588138 2667 321 84.4 blastp H85 1161 LYM137dandelion|gb161|DY804086 2668 321 85.1 blastp H86 1162 LYM137dandelion|gb161|DY813115 2669 321 83.8 blastp H87 1163 LYM137eucalyptus|gb166|CT980143 2670 321 83.1 blastp H88 1164 LYM137eucalyptus|gb166|CT981000 2671 321 81.3 blastp H89 1165 LYM137fescue|gb161|DT686472 2672 321 80.9 blastp H90 1166 LYM137flax|09v1|EU829592 2673 321 81 blastp H241 1167 LYM137gerbera|09v1|AJ750707 2674 321 85.6 blastp H242 1168 LYM137gerbera|09v1|AJ753127 2675 321 84.31 tblastn H243 1169 LYM137gerbera|09v1|AJ755440 2676 321 81.7 blastp H244 1170 LYM137ginger|gb164|DY352000 2677 321 85.5 blastp H91 1171 LYM137ginger|gb164|DY356913 2678 321 83.7 blastp H92 1172 LYM137grape|gb160|CA816335 2679 321 80.6 blastp H93 1173 LYM137grape|gb160|CB348289 2680 321 81.3 blastp H94 1174 LYM137grape|gb160|CB979641 2681 321 84.5 blastp H95 1175 LYM137iceplant|gb164|CA834927 2682 321 82.5 blastp H96 1176 LYM137ipomoea|gb157.2|BU690174 2683 321 82.2 blastp H97 1177 LYM137ipomoea|gb157.2|CJ738553 2684 321 82.9 blastp H98 1178 LYM137jatropha|09v1|GO247333 2685 321 85.6 blastp H245 1179 LYM137kiwi|gb166|FG413271 2686 321 83.1 blastp H99 1180 LYM137kiwi|gb166|FG421995 2687 321 84.2 blastp H100 1181 LYM137kiwi|gb166|FG429490 2688 321 83.9 blastp H101 1182 LYM137kiwi|gb166|FG461535 2689 321 84.2 blastp H102 1183 LYM137kiwi|gb166|FG501757 2690 321 83.6 blastp H103 1184 LYM137lettuce|gb157.2|CV700088 2691 321 83.8 blastp H104 1185 LYM137lettuce|gb157.2|DW046053 2692 321 83 blastp H105 1186 LYM137lettuce|gb157.2|DW049273 2693 321 83.8 blastp H106 1187 LYM137lettuce|gb157.2|DW077894 2694 321 83.8 blastp H107 1188 LYM137lettuce|gb157.2|DW080256 2695 321 83.7 blastp H108 1189 LYM137lettuce|gb157.2|DW080360 2696 321 83.1 blastp H109 1190 LYM137lettuce|gb157.2|DW112293 2697 321 83.8 blastp H110 1191 LYM137lettuce|gb157.2|DW145178 2698 321 83.8 blastp H111 1192 LYM137leymus|gb166|CD809209 2699 321 98.7 blastp H112 1193 LYM137liquorice|gb171|FS239986 2700 321 83.9 blastp H246 1194 LYM137liriodendron|gb166|CK743367 2701 321 85.3 blastp H113 1195 LYM137lolium|09v1|AU251012 2702 321 97.4 blastp H247 1196 LYM137lotus|09v1|LLBG662285 2703 321 85 blastp H248 1197 LYM137lotus|09v1|LLBI418687 2704 321 83.9 blastp H249 1198 LYM137lotus|09v1|LLGO006921 2705 321 83.7 blastp H250 1199 LYM137lovegrass|gb167|EH183574 2706 321 92.8 blastp H115 1200 LYM137lovegrass|gb167|EH185967 2707 321 90.1 blastp H116 1201 LYM137maize|gb170|AA979822 2708 321 93.4 blastp H251 1202 LYM137maize|gb170|AI612349 2709 321 94.7 blastp H252 1203 LYM137maize|gb170|EY962027 2710 321 82.89 tblastn H253 1204 LYM137maize|gb170|LLBG320994 2711 321 94.1 blastp H254 1205 LYM137maize|gb170|LLDQ245209 2712 321 99.3 blastp H255 1206 LYM137maize|gb170|LLDQ245775 2713 321 81.2 blastp H256 1207 LYM137maize|gb170|T18742 2714 321 93.4 blastp H257 1208 LYM137medicago|09v1|AW208139 2715 321 85.1 blastp H258 1209 LYM137medicago|09v1|AW287975 2716 321 83.6 blastp H259 1210 LYM137medicago|09v1|LLAJ846422 2717 321 82.47 tblastn H260 1211 LYM137melon|gb165|DV632825 2718 321 85 blastp H127 1212 LYM137melon|gb165|DV632919 2719 321 83.7 blastp H128 1213 LYM137millet|09v1|CD725778 2720 321 94.7 blastp H261 1214 LYM137millet|09v1|EVO454PM001999 2721 321 91.4 blastp H262 1215 LYM137monkeyflower|09v1|DV211090 2722 321 81.3 blastp H263 1216 LYM137monkeyflower|09v1|GO948368 2723 321 81.3 blastp H264 1217 LYM137nicotiana 2724 321 85.7 blastp H129 benthamiana|gb162|ES885186 1218LYM137 nuphar|gb166|FD386160 2725 321 85.8 blastp H130 1219 LYM137oak|gb170|CU656727 2726 321 83.1 blastp H265 1220 LYM137oak|gb170|SRR006307S0003551 2727 321 83.8 blastp H266 1221 LYM137oat|gb164|CN814837 2728 321 98 blastp H131 1222 LYM137 oil 2729 321 87.2blastp H132 palm|gb166|CN599457 1223 LYM137 oil 2730 321 84.5 blastpH133 palm|gb166|EL688664 1224 LYM137 onion|gb162|CF451442 2731 321 85.2blastp H134 1225 LYM137 papaya|gb165|EX238983 2732 321 83.1 blastp H1351226 LYM137 papaya|gb165|EX281727 2733 321 84.3 blastp H136 1227 LYM137peanut|gb171|CD038036 2734 321 84.4 blastp H267 1228 LYM137peanut|gb171|CD038042 2735 321 83.2 blastp H268 1229 LYM137peanut|gb171|EH042912 2736 321 85.1 blastp H269 1230 LYM137pea|09v1|EX570565 2737 321 83.7 blastp H270 1231 LYM137pepper|gb171|BM063192 2738 321 83 blastp H271 1232 LYM137pepper|gb171|CA518436 2739 321 81.8 blastp H272 1233 LYM137petunia|gb171|CV298826 2740 321 83 blastp H273 1234 LYM137petunia|gb171|CV299096 2741 321 83.7 blastp H274 1235 LYM137petunia|gb171|FN007657 2742 321 83.1 blastp H275 1236 LYM137poplar|gb170|AI161822 2743 321 81.8 blastp H276 1237 LYM137poplar|gb170|AI164812 2744 321 80.4 blastp H277 1238 LYM137poplar|gb170|CN517615 2745 321 81.58 tblastn H278 1239 LYM137poppy|gb166|FE964482 2746 321 82.6 blastp H150 1240 LYM137poppy|gb166|FE968489 2747 321 83.9 blastp H151 1241 LYM137potato|gb157.2|BE923747 2748 321 83.7 blastp H152 1242 LYM137potato|gb157.2|BF459639 2749 321 83.7 blastp H153 1243 LYM137potato|gb157.2|BI407078 2750 321 82.5 blastp H155 1244 LYM137potato|gb157.2|BQ046658 2751 321 82.5 blastp H156 1245 LYM137prunus|gb167|BU048009 2752 321 83.8 blastp H157 1246 LYM137prunus|gb167|BU572674 2753 321 83.8 blastp H158 1247 LYM137pseudoroegneria|gb167| 2754 321 98.7 blastp H159 FF344271 1248 LYM137radish|gb164|EV524412 2755 321 82.5 blastp H160 1249 LYM137radish|gb164|EV526732 2756 321 81.2 blastp H161 1250 LYM137radish|gb164|EV527806 2757 321 81.2 blastp H162 1251 LYM137radish|gb164|EV536949 2758 321 81.2 blastp H163 1252 LYM137radish|gb164|EV539087 2759 321 83.1 blastp H164 1253 LYM137radish|gb164|EV545248 2760 321 81.2 blastp H165 1254 LYM137radish|gb164|EV570492 2761 321 81.2 blastp H166 1255 LYM137radish|gb164|EW724465 2762 321 81.2 blastp H167 1256 LYM137radish|gb164|EW724737 2763 321 83.1 blastp H168 1257 LYM137radish|gb164|EW731970 2764 321 81.2 blastp H169 1258 LYM137radish|gb164|EW732728 2765 321 81.2 blastp H170 1259 LYM137radish|gb164|EX755641 2766 321 80.4 blastp H171 1260 LYM137radish|gb164|EX756784 2767 321 83.8 blastp H172 1261 LYM137radish|gb164|EX757824 2768 321 81.2 blastp H173 1262 LYM137rice|gb170|OS01G24690 2769 321 92.2 blastp H279 1263 LYM137rice|gb170|OS04G42270 2770 321 94.1 blastp H280 1264 LYM137rye|gb164|BE493987 2771 321 100 blastp H176 1265 LYM137safflower|gb162|EL378228 2772 321 82.4 blastp H177 1266 LYM137safflower|gb162|EL399454 2773 321 83.8 blastp H178 1267 LYM137safflower|gb162|EL411711 2774 321 81.7 blastp H179 1268 LYM137senecio|gb170|DY666439 2775 321 83.01 tblastn H281 1269 LYM137 solanum2776 321 82.5 blastp H282 phureja|09v1|SPHAA824956 1270 LYM137 solanum2777 321 82.69 tblastn H283 phureja|09v1|SPHBQ115070 1271 LYM137 solanum2778 321 83.7 blastp H284 phureja|09v1|SPHTOM289A 1272 LYM137sorghum|09v1|SB06G021660 2779 321 94.7 blastp H285 1273 LYM137sorghum|09v1|SB10G005240 2780 321 94.1 blastp H286 1274 LYM137soybean|gb168|AL365737 2781 321 85.6 blastp H182 1275 LYM137soybean|gb168|AW208139 2782 321 84.3 blastp H183 1276 LYM137soybean|gb168|AW287975 2783 321 85.6 blastp H184 1277 LYM137soybean|gb168|BE336250 2784 321 81.9 blastp H185 1278 LYM137soybean|gb168|BE336251 2785 321 84.5 blastp H186 1279 LYM137soybean|gb168|BI967538 2786 321 85 blastp H187 1280 LYM137spurge|gb161|BI993574 2787 321 83.8 blastp H188 1281 LYM137strawberry|gb164|CO378565 2788 321 83.7 blastp H189 1282 LYM137strawberry|gb164|EX685316 2789 321 82.5 blastp H190 1283 LYM137sugarcane|gb157.3|AI216927 2790 321 94.7 blastp H287 1284 LYM137sugarcane|gb157.3|BQ535570 2791 321 92.8 blastp H288 1285 LYM137sugarcane|gb157.3|BQ535956 2792 321 94.1 blastp H289 1286 LYM137sugarcane|gb157.3|BQ537453 2793 321 93.4 blastp H290 1287 LYM137sugarcane|gb157.3|CA106878 2794 321 94.7 blastp H291 1288 LYM137sugarcane|gb157.3|CA111839 2795 321 93.4 blastp H292 1289 LYM137sugarcane|gb157.3|CA113465 2796 321 92.11 tblastn H293 1290 LYM137sunflower|gb162|CD846067 2797 321 84.3 blastp H198 1291 LYM137sunflower|gb162|CD848213 2798 321 84.3 blastp H199 1292 LYM137sunflower|gb162|CD851130 2799 321 85.6 blastp H200 1293 LYM137sunflower|gb162|CD853875 2800 321 83.8 blastp H201 1294 LYM137switchgrass|gb167|DN140751 2801 321 92.8 blastp H202 1295 LYM137switchgrass|gb167|DN143966 2802 321 90.8 blastp H203 1296 LYM137switchgrass|gb167|FE603312 2803 321 91.4 blastp H204 1297 LYM137switchgrass|gb167|FE645253 2804 321 92.8 blastp H205 1298 LYM137tea|gb171|GE652357 2805 321 84.52 tblastn H294 1299 LYM137tea|gb171|GH613259 2806 321 81.2 blastp H295 1300 LYM137thellungiella|gb167|DN773656 2807 321 81.2 blastp H206 1301 LYM137tobacco|gb162|DV157653 2808 321 82.5 blastp H207 1302 LYM137tobacco|gb162|EB444171 2809 321 85.1 blastp H208 1303 LYM137tobacco|gb162|EB445443 2810 321 85.6 blastp H209 1304 LYM137tobacco|gb162|EB679214 2811 321 83.8 blastp H210 1305 LYM137tobacco|gb162|TOBRPL25A 2812 321 85.7 blastp H211 1306 LYM137tomato|09v1|AA824956 2813 321 81.8 blastp H296 1307 LYM137tomato|09v1|BQ115070 2814 321 83.8 blastp H297 1308 LYM137tomato|09v1|TOM289A 2815 321 83.7 blastp H298 1309 LYM137wheat|gb164|BE401860 2816 321 99.3 blastp H214 1310 LYM137wheat|gb164|BE403516 2817 321 99.3 blastp H215 1311 LYM137wheat|gb164|BE404488 2818 321 99.3 blastp H216 1312 LYM137wheat|gb164|CA612898 2819 321 82.89 tblastn H217 1313 LYM137zinnia|gb171|AU304473 2820 321 83 blastp H299 1314 LYM140apple|gb171|CN874007 2821 322 80.1 blastp H18 1315 LYM140banana|gb167|ES433790 2822 322 80 tblastn H1 1316 LYM140brachypodium|09v1|DV472528 2823 322 90.3 blastp H19 1317 LYM140cassava|09v1|BM259738 2824 322 80.3 blastp H20 1318 LYM140cassava|09v1|CK640886 2825 322 80.3 blastp H21 1319 LYM140castorbean|09v1|EG656528 2826 322 80.4 blastp H22 1320 LYM140chestnut|gb170|SRR006295S0060343 2827 322 80 blastp H23 1321 LYM140chestnut|gb170|SRR006296S0039724 2828 322 80.49 tblastn H24 1322 LYM140citrus|gb166|CB290479 2829 322 80.3 blastp H4 1323 LYM140cotton|gb164|BF271942 2830 322 81.4 blastp H5 1324 LYM140cotton|gb164|CA992695 2831 322 80.1 blastp H6 1325 LYM140cowpea|gb166|FC459791 2832 322 80.48 tblastn H7 1326 LYM140maize|gb170|AW331287 2833 322 89.2 blastp H25 1327 LYM140 oil 2834 32280.8 blastp H9 palm|gb166|ES414711 1328 LYM140 papaya|gb165|EX2277992835 322 80 blastp H10 1329 LYM140 radish|gb164|EV528272 2836 322 80.3blastp H11 1330 LYM140 rice|gb170|OS04G53210 2837 322 88.6 blastp H261331 LYM140 sorghum|09v1|SB06G028990 2838 322 88.9 blastp H27 1332LYM140 soybean|gb168|AW126193 2839 322 80 blastp H13 1333 LYM140sugarcane|gb157.3|CA071893 2840 322 88.1 blastp H28 1334 LYM140sunflower|gb162|BU671805 2841 322 80.1 blastp H15 1335 LYM140switchgrass|gb167|FE624047 2842 322 90.5 blastp H16 1336 LYM140wheat|gb164|BE415726 2843 322 98.1 blastp H17 1337 LYM140wheat|gb164|BF200613 2844 322 86.7 blastp H18 1338 LYM141rice|gb170|OS12G02910 2845 323 86.6 blastp H0 1339 LYM142barley|gb157SOLEXA| 2846 324 86.6 blastp H7 BQ761869 1340 LYM142brachypodium|09v1|DV478753 2847 324 86.8 blastp H8 1341 LYM142leymus|gb166|EG401596 2848 324 97.7 blastp H3 1342 LYM142pseudoroegneria|gb167| 2849 324 97.7 blastp H4 FF362922 1343 LYM142rice|gb170|OS02G33550 2850 324 83.9 blastp H9 1344 LYM142wheat|gb164|BE404843 2851 324 94.4 blastp H6 1345 LYM142wheat|gb164|CA631467 2852 324 83.9 blastp H7 1346 LYM144brachypodium|09v1|GT775853 2853 326 80.6 blastp H0 1347 LYM148brachypodium|09v1|DV478384 2854 328 91.1 blastp H10 1348 LYM148leymus|gb166|EG398961 2855 328 92.73 tblastn H2 1349 LYM148maize|gb170|AW060086 2856 328 84.5 blastp H11 1350 LYM148millet|09v1|EVO454PM023692 2857 328 82.9 blastp H12 1351 LYM148rice|gb170|OS06G45440 2858 328 82.4 blastp H13 1352 LYM148sorghum|09v1|SB10G026570 2859 328 83.3 blastp H14 1353 LYM148switchgrass|gb167|FE604043 2860 328 82.5 blastp H6 1354 LYM148switchgrass|gb167|FE641627 2861 328 81.1 blastp H7 1355 LYM148wheat|gb164|BE442896 2862 328 96.3 blastp H8 1356 LYM148wheat|gb164|BQ295259 2863 328 97 blastp H9 1357 LYM148wheat|gb164|BQ788641 2864 328 97 blastp H10 1358 LYM149brachypodium|09v1|DV488199 2865 329 83.2 blastp H5 1359 LYM149pseudoroegneria|gb167| 2866 329 87 blastp H2 FF346387 1360 LYM149wheat|gb164|BE429052 2867 329 87.2 blastp H3 1361 LYM149wheat|gb164|BQ620138 2868 329 87.5 blastp H4 1362 LYM149wheat|gb164|CA641424 2869 329 89.69 tblastn H5 1363 LYM152 arabidopsis2870 330 86.7 blastp H14 lyrata|09v1|BQ834051 1364 LYM152 arabidopsis2871 330 96.7 blastp H15 lyrata|09v1|JGIAL030307 1365 LYM152arabidopsis|gb165|AT4G25890 2872 330 82.5 tblastn H1 1366 LYM152 b 2873330 95 blastp H2 oleracea|gb161|DY027305 1367 LYM152 b 2874 330 93.4blastp H3 oleracea|gb161|DY028937 1368 LYM152 b 2875 330 94.17 tblastnH4 rapa|gb162|BG544013 1369 LYM152 b rapa|gb162|L35776 2876 330 92.6blastp H5 1370 LYM152 b rapa|gb162|L35823 2877 330 95 blastp H6 1371LYM152 canola|gb161|CD812096 2878 330 94.2 blastp H7 1372 LYM152canola|gb161|CD812552 2879 330 95 blastp H8 1373 LYM152canola|gb161|CD817037 2880 330 95 blastp H9 1374 LYM152canola|gb161|CD830347 2881 330 92.6 blastp H10 1375 LYM152radish|gb164|EV548235 2882 330 92.5 blastp H12 1376 LYM152radish|gb164|EW718196 2883 330 92.5 blastp H13 1377 LYM152thellungiella|gb167|BM985697 2884 330 91.7 blastp H14 1378 LYM153barley|gb157SOLEXA| 2885 331 81.5 blastp H6 BF625242 1379 LYM153brachypodium|09v1|SRR031796S0027091 2886 331 81.5 blastp H7 1380 LYM153cenchrus|gb166|EB654758 2887 331 80 blastp H2 1381 LYM153millet|09v1|EVO454PM017552 2888 331 83.1 blastp H8 1382 LYM153sorghum|09v1|SB10G003440 2889 331 81.5 blastp H9 1383 LYM153switchgrass|gb167|FE634744 2890 331 83.1 blastp H4 1384 LYM153wheat|gb164|CD490951 2891 331 94.03 tblastn H5 1385 LYM153wheat|gb164|CK215660 2892 331 80.3 tblastn H6 1386 LYM156barley|gb157SOLEXA| 2893 332 96.1 blastp H6 AL506124 1387 LYM156barley|gb157SOLEXA| 2894 332 93.1 blastp H7 BE195142 1388 LYM156pseudoroegneria|gb167| 2895 332 92.8 blastp H3 FF346665 1389 LYM156pseudoroegneria|gb167| 2896 332 86.3 blastp H4 FF354463 1390 LYM156rice|gb170|OS07G46830 2897 332 80 blastp H8 1391 LYM156wheat|gb164|BE637888 2898 332 91.8 blastp H6 1392 LYM157barley|gb157SOLEXA| 2899 333 94.9 blastp H1 BG299283 1393 LYM159wheat|gb164|CA598148 2900 334 81.01 tblastn H1 1394 LYM159wheat|gb164|CD866037 2901 334 87.7 blastp H2 1395 LYM159wheat|gb164|CD867356 2902 334 86.4 blastp H3 1396 LYM160wheat|gb164|BE399997 2903 335 87.6 tblastn H1 1397 LYM160wheat|gb164|BE500200 2904 335 80 blastp H2 1398 LYM161brachypodium|09v1|DV471902 2905 336 81.9 blastp H0 1398 LYM161brachypodium|09v1|DV471902 2905 444 81.02 tblastn H0 1399 LYM162maize|gb170|AW331105 2906 337 84.8 blastp H5 1400 LYM162millet|09v1|EVO454PM026751 2907 337 85.7 blastp H6 1401 LYM162sorghum|09v1|SB03G043995 2908 337 87.5 blastp H7 1402 LYM162sugarcane|gb157.3|BQ536349 2909 337 87.5 blastp H8 1403 LYM162switchgrass|gb167|FL738992 2910 337 83.9 blastp H4 1404 LYM162switchgrass|gb167|FL829126 2911 337 85.7 blastp H5 1405 LYM165maize|gb170|LLCO452769 2912 339 99.2 blastp H5 1406 LYM165sorghum|09v1|SB03G030690 2913 339 89.2 blastp H6 1407 LYM165sugarcane|gb157.3|BQ529806 2914 339 81.1 blastp H7 1408 LYM165sugarcane|gb157.3|CA084294 2915 339 90.4 blastp H8 1409 LYM165switchgrass|gb167|DN143471 2916 339 85.9 blastp H4 1410 LYM165switchgrass|gb167|DN144101 2917 339 85.7 blastp H5 1411 LYM166brachypodium|09v1|DV486893 2918 340 85.4 tblastn H1 1411 LYM166brachypodium|09v1|DV486893 2918 445 85.36 tblastn H1 1412 LYM170barley|gb157SOLEXA| 2919 341 91.6 blastp H7 AV915706 1413 LYM170brachypodium|09v1|SRR031797S0049196 2920 341 94.8 blastp H8 1414 LYM170maize|gb170|AI665902 2921 341 87.3 blastp H9 1415 LYM170maize|gb170|BE050628 2922 341 86.4 blastp H10 1416 LYM170sorghum|09v1|SB03G036440 2923 341 87.3 blastp H11 1417 LYM170sugarcane|gb157.3|CA067017 2924 341 88.3 blastp H12 1418 LYM170switchgrass|gb167|DN142710 2925 341 87.3 blastp H6 1419 LYM170wheat|gb164|BE415371 2926 341 93.5 blastp H7 1420 LYM172brachypodium|09v1|DV489358 2927 342 87.6 blastp H11 1421 LYM172maize|gb170|AA979770 2928 342 81.7 blastp H12 1422 LYM172maize|gb170|AI711966 2929 342 81.2 blastp H13 1423 LYM172maize|gb170|AI947521 2930 342 80.71 tblastn H14 1424 LYM172maize|gb170|AW120145 2931 342 82.9 blastp H15 1425 LYM172millet|09v1|EVO454PM002481 2932 342 85.6 tblastn H16 1426 LYM172rice|gb170|OS02G08364 2933 342 81.8 blastp H17 1427 LYM172sorghum|09v1|SB04G005430 2934 342 80.43 tblastn H18 1428 LYM172sorghum|09v1|SB10G025800 2935 342 83.9 blastp H19 1429 LYM172sugarcane|gb157.3|CA071007 2936 342 80.1 blastp H20 1430 LYM172switchgrass|gb167|FL692588 2937 342 80.7 blastp H9 1431 LYM172wheat|gb164|BE400761 2938 342 81.25 tblastn H10 1432 LYM172wheat|gb164|BE498868 2939 342 87.77 tblastn H11 1433 LYM213switchgrass|gb167|FE620008 2940 343 80.4 blastp H1 1433 LYM213switchgrass|gb167|FE620008 2940 386 88.7 blastp H1 1434 LYM174maize|gb170|AW144917 2941 344 89.4 blastp H3 1435 LYM174maize|gb170|AW267379 2942 344 86.6 blastp H4 1436 LYM174sugarcane|gb157.3|CA089309 2943 344 92.31 tblastn H5 1437 LYM174switchgrass|gb167|DN150662 2944 344 80.9 blastp H3 1438 LYM175maize|gb170|AW498464 2945 345 81.2 blastp H0 1439 LYM175rice|gb170|OS01G69090 2946 345 95 blastp H1 1439 LYM175rice|gb170|OS01G69090 2946 446 100 blastp H1 1440 LYM215sorghum|09v1|SB03G043980 2947 345 81.2 blastp H2 1440 LYM215sorghum|09v1|SB03G043980 2947 387 94.6 blastp H2 1441 LYM176maize|gb170|CA452713 2948 346 82.2 blastp H2 1442 LYM176sorghum|09v1|SB03G036470 2949 346 83 blastp H3 1443 LYM176switchgrass|gb167|FE606366 2950 346 82 blastp H2 1444 LYM178brachypodium|09v1|DV472161 2951 347 84.9 blastp H9 1445 LYM178brachypodium|09v1|SRR031797S0177787 2952 347 84.6 blastp H10 1446 LYM178fescue|gb161|DT674427 2953 347 89.4 blastp H1 1447 LYM178leymus|gb166|EG394591 2954 347 84.08 tblastn H2 1448 LYM178maize|gb170|W21746 2955 347 83.4 blastp H11 1449 LYM178millet|09v1|EVO454PM001531 2956 347 83.1 blastp H12 1450 LYM178pseudoroegneria|gb167| 2957 347 93.6 blastp H3 FF358503 1451 LYM178sorghum|09v1|SB03G008890 2958 347 83.1 blastp H13 1452 LYM178sorghum|09v1|SB07G001060 2959 347 81.9 blastp H14 1453 LYM178sugarcane|gb157.3|CA066169 2960 347 82.4 blastp H15 1454 LYM178sugarcane|gb157.3|CA079726 2961 347 83.1 blastp H16 1455 LYM178switchgrass|gb167|FE636508 2962 347 82.4 blastp H8 1456 LYM178wheat|gb164|BQ620752 2963 347 94.7 blastp H9 1457 LYM179sorghum|09v1|SB08G006470 2964 348 86.5 blastp H0 1458 LYM107brachypodium|09v1|GT808738 2965 349 86.9 blastp H2 1459 LYM107maize|gb170|CF075587 2966 349 95.2 blastp H3 1460 LYM107rice|gb170|OS05G26660 2967 349 86.4 blastp H4 1461 LYM107sorghum|09v1|SB03G036480 2968 349 95 blastp H5 1462 LYM109maize|gb170|BG517163 2969 350 82.62 tblastn H1 1462 LYM109maize|gb170|BG517163 2969 447 82.6 tblastn H1 1463 LYM109sorghum|09v1|SB05G003660 2970 350 88.75 tblastn H2 1463 LYM109sorghum|09v1|SB05G003660 2970 447 88.87 tblastn H2 1464 LYM112maize|gb170|CF037322 2971 351 95.4 blastp H1 1464 LYM112maize|gb170|CF037322 2971 448 93.96 tblastn H1 1465 LYM112sorghum|09v1|SB02G039985 2972 351 92.43 tblastn H2 1465 LYM112sorghum|09v1|SB02G039985 2972 448 84.8 blastp H2 1466 LYM115sorghum|09v1|SB01G043900 2973 353 90.19 tblastn H0 1467 LYM116sorghum|09v1|SB06G031340 2974 354 88.2 blastp H3 1468 LYM116switchgrass|gb167|FE653493 2975 354 80.88 tblastn H2 1469 LYM116switchgrass|gb167|FL790906 2976 354 80.88 tblastn H3 1470 LYM117maize|gb170|GFXAF243041X1 2977 355 84.4 blastp H2 1470 LYM117maize|gb170|GFXAF243041X1 2977 449 84.5 blastp H2 1471 LYM117sorghum|09v1|SB07G027220 2978 355 82.3 blastp H3 1471 LYM117sorghum|09v1|SB07G027220 2978 449 82.3 blastp H3 1472 LYM121rice|gb170|OS12G02620 2979 357 90.6 blastp H1 1473 LYM123barley|gb157SOLEXA| 2980 358 85.5 blastp H4 AF268595 1474 LYM123brachypodium|09v1|GT761722 2981 358 84 blastp H5 1475 LYM123maize|gb170|AI795558 2982 358 85.2 blastp H6 1476 LYM123sorghum|09v1|SB06G031680 2983 358 86.3 blastp H7 1477 LYM123wheat|gb164|BE401871 2984 358 85.6 blastp H4 1478 LYM135brachypodium|09v1|DV480514 2985 359 93.1 blastp H1 1479 LYM135maize|gb170|CB885667 2986 359 80.2 blastp H2 1480 LYM135sorghum|09v1|SB10G007850 2987 359 84.1 blastp H3 1481 LYM138brachypodium|09v1|GT810825 2988 360 84 blastp H2 1482 LYM138maize|gb170|AI612333 2989 360 86.17 tblastn H3 1483 LYM138sorghum|09v1|SB06G031570 2990 360 86.33 tblastn H4 1484 LYM146brachypodium|09v1|SRR031798S0143459 2991 361 84.3 blastp H2 1485 LYM146rice|gb170|OS03G21730 2992 361 86.4 blastp H3 1486 LYM146sorghum|09v1|SB01G036160 2993 361 96 blastp H4 1487 LYM147sorghum|09v1|SB03G003200 2994 362 82 blastp H0 1488 LYM154wheat|gb164|BE500571 2995 363 82.5 blastp H0 1489 LYM155brachypodium|09v1|DV479969 2996 364 84.7 blastp H3 1489 LYM155brachypodium|09v1|DV479969 2996 451 83.5 blastp H3 1490 LYM155rice|gb170|OS03G58890 2997 364 81.3 blastp H4 1490 LYM155rice|gb170|OS03G58890 2997 451 80 blastp H4 1491 LYM155wheat|gb164|BQ801019 2998 364 92.3 blastp H3 1491 LYM155wheat|gb164|BQ801019 2998 451 91.6 blastp H3 1492 LYM180brachypodium|09v1|DV473436 2999 365 82.9 blastp H0 1492 LYM180brachypodium|09v1|DV473436 2999 452 83.54 tblastn H0 1493 LYM181brachypodium|09v1|DV485149 3000 366 85.3 blastp H3 1493 LYM181brachypodium|09v1|DV485149 3000 453 84.68 tblastn H3 1494 LYM181maize|gb170|DR452216 3001 366 80.8 blastp H4 1494 LYM181maize|gb170|DR452216 3001 453 81.25 tblastn H4 1495 LYM181rice|gb170|OS07G32010 3002 366 82.8 blastp H5 1496 LYM181sorghum|09v1|SB02G034110 3003 366 83.5 blastp H6 1497 LYM181wheat|gb164|BE425377 3004 453 87.16 tblastn H2 1498 LYM181wheat|gb164|BG905028 3005 453 93.58 tblastn H3 1499 LYM182brachypodium|09v1|GT780326 3006 367 87.64 tblastn H8 1500 LYM182maize|gb170|AI795737 3007 367 84.27 tblastn H9 1501 LYM182millet|09v1|EVO454PM084568 3008 367 82.02 tblastn H10 1502 LYM182rice|gb170|OS04G33300 3009 367 82.02 tblastn H11 1503 LYM182sorghum|09v1|SB06G015280 3010 367 83.15 tblastn H12 1504 LYM182sugarcane|gb157.3|CA066047 3011 367 83.15 tblastn H13 1505 LYM182switchgrass|gb167|FE610729 3012 367 82.02 tblastn H6 1506 LYM182switchgrass|gb167|FL699214 3013 367 83.15 tblastn H7 1507 LYM182wheat|gb164|BF200136 3014 367 95.51 tblastn H8 1508 LYM184brachypodium|09v1|DV476770 3015 454 82.68 tblastn H5 1509 LYM184brachypodium|09v1|GT762544 3016 454 82.61 tblastn H6 1510 LYM184brachypodium|09v1|SRR031799S0153720 3017 454 82.68 tblastn H7 1511LYM184 leymus|gb166|EG385150 3018 454 84.8 blastp H3 1512 LYM184maize|gb170|AI691210 3019 382 100 blastp H8 1512 LYM184maize|gb170|AI691210 3019 454 80.87 tblastn H8 1513 LYM206sorghum|09v1|SB07G021090 3020 382 84.5 blastp H2 1513 LYM206sorghum|09v1|SB07G021090 3020 454 80.52 tblastn H2 1514 LYM184switchgrass|gb167|FL704827 3021 454 80.5 blastp H4 1515 LYM184wheat|gb164|AL821254 3022 368 82.66 tblastn H5 1515 LYM184wheat|gb164|AL821254 3022 454 86.96 tblastn H5 1516 LYM185pseudoroegneria|gb167| 3023 455 91.53 tblastn H1 FF360278 1517 LYM185wheat|gb164|BG906077 3024 455 85.31 tblastn H2 1518 LYM186brachypodium|09v1|GT761126 3025 370 90.7 blastp H4 1519 LYM186maize|gb170|BE552887 3026 370 82.5 tblastn H5 1520 LYM186rice|gb170|OS10G39930 3027 370 86.3 blastp H6 1521 LYM186sorghum|09v1|SB01G030050 3028 370 86.5 blastp H7 1522 LYM186wheat|gb164|BE429425 3029 370 97.6 blastp H4 1523 LYM188brachypodium|09v1|DV475481 3030 371 92.4 blastp H8 1523 LYM188brachypodium|09v1|DV475481 3030 456 89.41 tblastn H8 1524 LYM188maize|gb170|AI622726 3031 371 87.2 blastp H9 1524 LYM188maize|gb170|AI622726 3031 456 83.47 tblastn H9 1525 LYM188maize|gb170|AW424865 3032 371 86 blastp H10 1525 LYM188maize|gb170|AW424865 3032 456 83.9 tblastn H10 1526 LYM188millet|09v1|EVO454PM011140 3033 456 85.17 tblastn H11 1527 LYM188pseudoroegneria|gb167| 3034 456 80.5 blastp H3 FF341644 1528 LYM188rice|gb170|OS03G53960 3035 371 88.2 blastp H12 1528 LYM188rice|gb170|OS03G53960 3035 456 84.75 tblastn H12 1529 LYM188sorghum|09v1|SB01G007950 3036 371 87.4 blastp H13 1529 LYM188sorghum|09v1|SB01G007950 3036 456 84.32 tblastn H13 1530 LYM188sugarcane|gb157.3|BQ530106 3037 371 87.4 blastp H14 1530 LYM188sugarcane|gb157.3|BQ530106 3037 456 84.32 tblastn H14 1531 LYM188switchgrass|gb167|FL709807 3038 456 84.32 tblastn H7 1532 LYM188wheat|gb164|CA742940 3039 456 81.78 tblastn H8 1533 LYM193leymus|gb166|EG381914 3040 459 87.1 tblastn H1 1534 LYM193wheat|gb164|BQ236678 3041 459 85.26 tblastn H2 1535 LYM194brachypodium|09v1|SRR031796S0004815 3042 375 84.8 blastp H0 1536 LYM194maize|gb170|BQ539102 3043 375 82.1 blastp H1 1537 LYM194sorghum|09v1|SB06G015320 3044 375 84.9 blastp H2 1538 LYM194switchgrass|gb167|FE645079 3045 375 82.9 blastp H3 1539 LYM194wheat|gb164|BE518078 3046 375 96.3 blastp H4 1540 LYM197sugarcane|gb157.3|BQ536804 3047 377 88.57 tblastn H2 1541 LYM198sorghum|09v1|SB01G045460 3048 378 85.5 blastp H1 1542 LYM201aquilegia|gb157.3|DR915888 3049 379 82.4 blastp H1 1543 LYM201arabidopsis 3050 379 80.07 tblastn H19 lyrata|09v1|JGIAL022871 1544LYM201 artemisia|gb164|EY033288 3051 379 80.5 blastp H2 1545 LYM201brapa| 3052 379 80.3 blastp H3 gb162|CV433700 1546 LYM201brachypodium|09v1|DV471345 3053 379 93.8 blastp H20 1547 LYM201brachypodium|09v1|GT759255 3054 379 81.2 blastp H21 1548 LYM201cassava|09v1|DQ138370 3055 379 82.2 blastp H22 1549 LYM201cassava|09v1|FF380539 3056 379 81.3 blastp H23 1550 LYM201castorbean|09v1|EE256048 3057 379 81.4 blastp H24 1551 LYM201chestnut|gb170|SRR006295S0006313 3058 379 80.6 blastp H25 1552 LYM201cotton|gb164|AI728378 3059 379 81.7 blastp H7 1553 LYM201cotton|gb164|CO070970 3060 379 82 blastp H8 1554 LYM201cucumber|09v1|AM731598 3061 379 81.7 blastp H26 1555 LYM201lotus|09v1|BI419437 3062 379 80.5 blastp H27 1556 LYM201maize|gb170|AI978254 3063 379 98.2 blastp H28 1557 LYM201maize|gb170|DR971118 3064 379 80.1 blastp H29 1558 LYM201medicago|09v1|AW684099 3065 379 80.7 blastp H30 1559 LYM201oak|gb170|CU656181 3066 379 82.56 tblastn H31 1560 LYM201poplar|gb170|BI069637 3067 379 81.3 blastp H32 1561 LYM201poplar|gb170|BU887151 3068 379 80.7 blastp H33 1562 LYM201rice|gb170|OS02G34560 3069 379 95.2 blastp H34 1563 LYM201 solanum 3070379 81.4 blastp H35 phureja|09v1|SPHBG123984 1564 LYM201 solanum 3071379 81.2 blastp H36 phureja|09v1|SPHBG129477 1565 LYM201sorghum|09v1|SB04G022350 3072 379 98.4 blastp H37 1566 LYM201soybean|gb168|AL367670 3073 379 80.7 blastp H15 1567 LYM201soybean|gb168|AW684099 3074 379 80.5 blastp H16 1568 LYM201sugarcane|gb157.3|CA065291 3075 379 98.6 blastp H38 1569 LYM201switchgrass|gb167|FE641755 3076 379 98.2 blastp H18 1570 LYM201tomato|09v1|BG123984 3077 379 81.4 blastp H39 1571 LYM201tomato|09v1|BG129477 3078 379 81.2 blastp H40 1572 LYM201wheat|gb164|BE403168 3079 379 93.2 blastp H19 1573 LYM203barley|gb157SOLEXA| 3080 380 84.7 blastp H9 BI949918 1574 LYM203lolium|09v1|AU247009 3081 380 85.2 blastp H10 1575 LYM203maize|gb170|AI629675 3082 380 95.7 blastp H11 1576 LYM203millet|09v1|EVO454PM058394 3083 380 81.7 blastp H12 1577 LYM203rice|gb170|OS02G08380 3084 380 89.2 blastp H13 1578 LYM203sorghum|09v1|SB04G005460 3085 380 96.8 blastp H14 1579 LYM203sugarcane|gb157.3|CA119568 3086 380 94.1 blastp H15 1580 LYM203switchgrass|gb167|DN142920 3087 380 95.2 blastp H6 1581 LYM203switchgrass|gb167|FE617741 3088 380 95.7 blastp H7 1582 LYM203wheat|gb164|BQ801966 3089 380 85.7 blastp H8 1583 LYM203wheat|gb164|BQ903230 3090 380 86.2 blastp H9 1584 LYM206maize|gb170|AW055997 3091 382 84.1 blastp H3 1585 LYM207maize|gb170|BM340289 3092 383 86.5 blastp H2 1586 LYM207sorghum|09v1|SB06G023870 3093 383 94.3 blastp H3 1587 LYM207switchgrass|gb167|FE601320 3094 383 82.3 blastp H2 1588 LYM208maize|gb170|AI691368 3095 384 94.4 blastp H6 1589 LYM208rice|gb170|OS09G01690 3096 384 82 blastp H7 1590 LYM208sorghum|09v1|SB01G032070 3097 384 92.1 blastp H8 1591 LYM208sorghum|09v1|SB08G002510 3098 384 86.6 blastp H9 1592 LYM208switchgrass|gb167|FE612629 3099 384 90.4 blastp H5 1593 LYM208switchgrass|gb167|FL729765 3100 384 90.4 blastp H6 1594 LYM212barley|gb157SOLEXA| 3101 385 80.3 blastp H6 BF623682 1595 LYM212maize|gb170|AI677474 3102 385 88.5 blastp H7 1596 LYM212rice|gb170|OS03G07910 3103 385 80.11 tblastn H8 1597 LYM212sorghum|09v1|SB01G045480 3104 385 92.5 blastp H9 1598 LYM212sugarcane|gb157.3|CA088789 3105 385 92 blastp H10 1599 LYM212wheat|gb164|BE402242 3106 385 80.38 tblastn H6 1600 LYM213maize|gb170|AW282249 3107 386 90.9 blastp H1 1601 LYM213sorghum|09v1|SB06G018770 3108 386 91.7 blastp H2 1602 LYM215switchgrass|gb167|FE618086 3109 387 90.42 tblastn H2 1603 LYM217sorghum|09v1|SB01G043910 3110 388 88.2 blastp H3 1604 LYM217sugarcane|gb157.3|CA136491 3111 388 87.7 blastp H4 1605 LYM217switchgrass|gb167|FE606442 3112 388 86.7 blastp H3 1606 LYM221brachypodium|09v1|GT792319 3113 391 83.8 blastp H1 1606 LYM221brachypodium|09v1|GT792319 3113 461 81.3 blastp H1 1607 LYM221rice|gb170|OS03G24870 3114 391 82.9 blastp H2 1607 LYM221rice|gb170|OS03G24870 3114 461 80.5 blastp H2 1608 LYM221sorghum|09v1|SB01G034610 3115 391 90.7 blastp H3 1608 LYM221sorghum|09v1|SB01G034610 3115 461 88.7 blastp H3 1609 LYM224brachypodium|09v1|GT762108 3116 393 82.4 blastp H2 1610 LYM224sorghum|09v1|SB02G040000 3117 393 92.9 blastp H3 1611 LYM224switchgrass|gb167|FE617506 3118 393 83.19 tblastn H2 1612 LYM227sorghum|09v1|SB01G043140 3119 394 88.3 blastp H1 1613 LYM228sorghum|09v1|SB09G006910 3120 395 85 blastp H1 1613 LYM228sorghum|09v1|SB09G006910 3120 462 83.7 blastp H1 1614 LYM232sorghum|09v1|SB02G000450 3121 396 80.4 blastp H3 1615 LYM232sugarcane|gb157.3|CA073189 3122 396 80.8 blastp H4 1616 LYM232switchgrass|gb167|FL849399 3123 396 80.7 blastp H3 1617 LYM233brachypodium|09v1|TMPLOS01G70020T1 3124 397 99.6 blastp H0 1618 LYM234rice|gb170|OS07G38290 3125 398 81.3 blastp H0 1619 LYM236apple|gb171|CN488568 3126 399 89.1 blastp H99 1620 LYM236apple|gb171|CN883100 3127 399 89.6 blastp H100 1621 LYM236aquilegia|gb157.3|DR919774 3128 399 87.4 blastp H3 1622 LYM236arabidopsis 3129 399 83.9 blastp H101 lyrata|09v1|JGIAL005113 1623LYM236 arabidopsis 3130 399 86.89 tblastn H102 lyrata|09v1|JGIAL0066461624 LYM236 arabidopsis|gb165|AT1G54340 3131 399 83.5 blastp H4 1625LYM236 arabidopsis|gb165|AT1G65930 3132 399 87.1 blastp H5 1626 LYM236artemisia|gb164|EY034635 3133 399 87.9 blastp H6 1627 LYM236avocado|gb164|CO995120 3134 399 91.3 blastp H7 1628 LYM236 b 3135 39987.2 blastp H8 oleracea|gb161|DY028218 1629 LYM236 b 3136 399 87.2blastp H9 rapa|gb162|CX269094 1630 LYM236 b 3137 399 84.3 tblastn H10rapa|gb162|GFXAF258246X1 1631 LYM236 b rapa|gb162|L47856 3138 399 87.2blastp H11 1632 LYM236 barley|gb157SOLEXA| 3139 399 89.3 blastp H103AL502504 1633 LYM236 basilicum|gb157.3|DY322368 3140 399 87.7 blastp H131634 LYM236 bean|gb167|CA896841 3141 399 87.9 blastp H14 1635 LYM236brachypodium|09v1|DV478973 3142 399 85.3 blastp H104 1636 LYM236brachypodium|09v1|DV482439 3143 399 90.5 blastp H105 1637 LYM236cacao|gb167|DQ448875 3144 399 89.2 blastp H17 1638 LYM236canola|gb161|BQ704958 3145 399 87.2 blastp H18 1639 LYM236canola|gb161|CD817340 3146 399 87.2 blastp H19 1640 LYM236canola|gb161|CD833108 3147 399 83.9 blastp H20 1641 LYM236canola|gb161|CX189442 3148 399 86.5 blastp H21 1642 LYM236canola|gb161|DY011390 3149 399 87.2 blastp H22 1643 LYM236cassava|09v1|CK642610 3150 399 90.1 blastp H106 1644 LYM236cassava|09v1|DV457942 3151 399 87.5 blastp H107 1645 LYM236castorbean|09v1|EE256632 3152 399 86.1 blastp H108 1646 LYM236castorbean|09v1|EE259479 3153 399 90.6 blastp H109 1647 LYM236centaurea|gb166|EH731203 3154 399 81.2 blastp H26 1648 LYM236centaurea|gb166|EL932337 3155 399 86.6 blastp H27 1649 LYM236chestnut|gb170|SRR006295S0002580 3156 399 82.27 tblastn H110 1650 LYM236chestnut|gb170|SRR006295S0002701 3157 399 89.6 blastp H111 1651 LYM236cichorium|gb171|EH675189 3158 399 87.3 blastp H112 1652 LYM236cichorium|gb171|EH683726 3159 399 89.1 blastp H113 1653 LYM236citrus|gb166|AF176669 3160 399 90.6 blastp H30 1654 LYM236citrus|gb166|CD573911 3161 399 85.1 blastp H31 1655 LYM236coffea|gb157.2|DV663279 3162 399 87.8 blastp H32 1656 LYM236cotton|gb164|AI727260 3163 399 87.2 blastp H33 1657 LYM236cotton|gb164|BF278588 3164 399 83.5 blastp H34 1658 LYM236cowpea|gb166|FC458136 3165 399 89.1 blastp H35 1659 LYM236cynara|gb167|GE577243 3166 399 86.47 tblastn H36 1660 LYM236cynara|gb167|GE579663 3167 399 88.6 blastp H37 1661 LYM236dandelion|gb161|DY804243 3168 399 86.96 tblastn H38 1662 LYM236eucalyptus|gb166|X97063 3169 399 88 blastp H39 1663 LYM236fescue|gb161|CK801045 3170 399 89.8 blastp H40 1664 LYM236fescue|gb161|DT674724 3171 399 90 blastp H41 1665 LYM236ginger|gb164|DY360289 3172 399 91.3 blastp H42 1666 LYM236grape|gb160|BM436755 3173 399 89.9 blastp H43 1667 LYM236kiwi|gb166|FG396670 3174 399 88.2 blastp H44 1668 LYM236kiwi|gb166|FG397107 3175 399 88.7 blastp H45 1669 LYM236kiwi|gb166|FG397291 3176 399 89.4 blastp H46 1670 LYM236lettuce|gb157.2|DW088948 3177 399 87.4 blastp H47 1671 LYM236leymus|gb166|CD809160 3178 399 89.6 blastp H48 1672 LYM236liriodendron|gb166|CK762229 3179 399 88.2 blastp H49 1673 LYM236lotus|09v1|AW428686 3180 399 89.4 blastp H114 1674 LYM236lotus|09v1|BP033879 3181 399 83.7 blastp H115 1675 LYM236lovegrass|gb167|DN480596 3182 399 90.8 blastp H51 1676 LYM236maize|gb170|AI600815 3183 399 93.7 blastp H116 1677 LYM236maize|gb170|AW313297 3184 399 92.2 blastp H117 1678 LYM236maize|gb170|W21690 3185 399 91.3 blastp H118 1679 LYM236medicago|09v1|AW191201 3186 399 88.2 blastp H119 1680 LYM236medicago|09v1|AW689032 3187 399 84.9 blastp H120 1681 LYM236millet|09v1|CD725798 3188 399 92.5 blastp H121 1682 LYM236millet|09v1|EVO454PM002708 3189 399 94.2 blastp H122 1683 LYM236monkeyflower|09v1|DV206036 3190 399 87.4 blastp H123 1684 LYM236nicotiana 3191 399 86.5 blastp H56 benthamiana|gb162|CK291144 1685LYM236 oil 3192 399 87.3 blastp H57 palm|gb166|EL684429 1686 LYM236peanut|gb171|CD038682 3193 399 87.9 blastp H124 1687 LYM236pea|09v1|CD860585 3194 399 89.6 blastp H125 1688 LYM236pepper|gb171|BM061761 3195 399 88 blastp H126 1689 LYM236pepper|gb171|CA516582 3196 399 85.3 blastp H127 1690 LYM236petunia|gb171|DC240208 3197 399 88.2 blastp H128 1691 LYM236physcomitrella|10v1|AW497149 3198 399 82.2 blastp H129 1692 LYM236pine|gb157.2|AW010292 3199 399 85.6 blastp H62 1693 LYM236pine|gb157.2|BX249826 3200 399 85.6 blastp H63 1694 LYM236poplar|gb170|AI161956 3201 399 89.6 blastp H130 1695 LYM236poplar|gb170|BI127706 3202 399 86.6 blastp H131 1696 LYM236poplar|gb170|BI131610 3203 399 86.8 blastp H132 1697 LYM236poplar|gb170|BU821063 3204 399 90.4 blastp H133 1698 LYM236potato|gb157.2|BG591093 3205 399 88 blastp H66 1699 LYM236prunus|gb167|AF367443 3206 399 89.4 blastp H67 1700 LYM236radish|gb164|EV526847 3207 399 85.8 blastp H68 1701 LYM236radish|gb164|EV531225 3208 399 86.9 blastp H69 1702 LYM236rice|gb170|OS01G14580 3209 399 84.8 blastp H134 1703 LYM236rice|gb170|OS01G46610 3210 399 93 blastp H135 1704 LYM236rye|gb164|BE494776 3211 399 86.17 tblastn H72 1705 LYM236safflower|gb162|EL372795 3212 399 87.3 blastp H73 1706 LYM236safflower|gb162|EL374725 3213 399 89.1 blastp H74 1707 LYM236 solanum3214 399 86.3 blastp H136 phureja|09v1|SPHBG131802 1708 LYM236 solanum3215 399 87.7 blastp H137 phureja|09v1|SPHBG629432 1709 LYM236sorghum|09v1|SB03G029840 3216 399 92 blastp H138 1710 LYM236sorghum|09v1|SB09G029110 3217 399 94.7 blastp H139 1711 LYM236soybean|gb168|AW257518 3218 399 88.7 blastp H77 1712 LYM236soybean|gb168|AW689032 3219 399 85.6 blastp H78 1713 LYM236soybean|gb168|FF554826 3220 399 84.7 blastp H79 1714 LYM236soybean|gb168|SOYIDH 3221 399 89.4 blastp H80 1715 LYM236spikemoss|gb165|FE441231 3222 399 84.2 blastp H81 1716 LYM236spikemoss|gb165|FE443181 3223 399 82.3 blastp H82 1717 LYM236spruce|gb162|CO225856 3224 399 85 blastp H83 1718 LYM236strawberry|gb164|DV438767 3225 399 82.6 blastp H84 1719 LYM236sugarcane|gb157.3|BU103347 3226 399 94.5 blastp H140 1720 LYM236sugarcane|gb157.3|CA070718 3227 399 92.5 blastp H141 1721 LYM236sunflower|gb162|CD846861 3228 399 86.6 blastp H87 1722 LYM236sunflower|gb162|CD854278 3229 399 87.9 blastp H88 1723 LYM236switchgrass|gb167|DN142415 3230 399 92 blastp H89 1724 LYM236switchgrass|gb167|DN143508 3231 399 95.4 blastp H90 1725 LYM236switchgrass|gb167|DN150237 3232 399 95.2 blastp H91 1726 LYM236switchgrass|gb167|DN151575 3233 399 92.2 blastp H92 1727 LYM236thellungiella|gb167|DN774112 3234 399 87.14 tblastn H93 1728 LYM236tobacco|gb162|DV158343 3235 399 83.3 blastp H94 1729 LYM236tobacco|gb162|X77944 3236 399 88.5 blastp H95 1730 LYM236tomato|09v1|BG131802 3237 399 85.6 blastp H142 1731 LYM236tomato|09v1|BG629432 3238 399 87.3 blastp H143 1732 LYM236triphysaria|gb164|DR171747 3239 399 88.4 blastp H98 1733 LYM236wheat|gb164|BE442540 3240 399 84.1 blastp H99 1734 LYM238rice|gb170|OS05G45080 3241 400 95.4 blastp H0 1735 LYM240barley|gb157SOLEXA| 3242 402 91.9 blastp H9 AL508021 1736 LYM240brachypodium|09v1|GT810642 3243 402 91.9 blastp H10 1737 LYM240maize|gb170|DR972790 3244 402 84.2 blastp H11 1738 LYM240sorghum|09v1|SB02G038240 3245 402 84.2 blastp H12 1739 LYM240sugarcane|gb157.3|CA075929 3246 402 82.3 blastp H13 1740 LYM240switchgrass|gb167|FE597498 3247 402 81.6 blastp H6 1741 LYM240switchgrass|gb167|FE610847 3248 402 80 blastp H7 1742 LYM240switchgrass|gb167|FL960804 3249 402 81.6 blastp H8 1743 LYM240wheat|gb164|CA674491 3250 402 89.93 tblastn H9 1744 LYM242barley|gb157SOLEXA| 3251 404 82.2 blastp H7 BE412570 1745 LYM242brachypodium|09v1|GT764573 3252 404 86.1 blastp H8 1746 LYM242maize|gb170|AI746053 3253 404 83.4 blastp H9 1747 LYM242millet|09v1|EVO454PM008771 3254 404 85 blastp H10 1748 LYM242sorghum|09v1|SB03G003160 3255 404 82.6 blastp H11 1749 LYM242sugarcane|gb157.3|BQ534251 3256 404 83.8 blastp H12 1750 LYM242switchgrass|gb167|DN143169 3257 404 85.1 blastp H5 1751 LYM242switchgrass|gb167|FE654179 3258 404 85 blastp H6 1752 LYM242wheat|gb164|BE403285 3259 404 82.6 blastp H7 1753 LYM248brachypodium|09v1|GT773582 3260 407 84.5 blastp H3 1754 LYM248maize|gb170|AI966957 3261 407 88.5 blastp H4 1755 LYM248sorghum|09v1|SB04G000645 3262 407 88.2 blastp H5 1756 LYM248switchgrass|gb167|DN149511 3263 407 81.1 blastp H2 1757 LYM248wheat|gb164|BE418033 3264 407 84.89 tblastn H3 1758 LYM250rice|gb170|OS09G38700 3265 409 100 tblastn H0 1758 LYM250rice|gb170|OS09G38700 3265 463 97.78 tblastn H0 1759 LYM251antirrhinum|gb166|AJ560114 3266 410 82 blastp H1 1760 LYM251apple|gb171|CN492643 3267 410 80.1 blastp H76 1761 LYM251 arabidopsis3268 410 81.4 blastp H77 lyrata|09v1|JGIAL012198 1762 LYM251arabidopsis|gb165|AT2G17380 3269 410 80.7 blastp H3 1763 LYM251arabidopsis|gb165|AT4G35410 3270 410 80.12 tblastn H4 1764 LYM251 b 3271410 81.4 blastp H5 oleracea|gb161|AM385265 1765 LYM251 brapa|gb162|L33527 3272 410 81.4 blastp H6 1766 LYM251banana|gb167|FF558300 3273 410 81.37 tblastn H7 1767 LYM251barley|gb157SOLEXA| 3274 410 81.4 blastp H78 BE421807 1768 LYM251basilicum|gb157.3|DY343154 3275 410 80.12 tblastn H9 1769 LYM251bean|gb167|CV536707 3276 410 80.1 blastp H11 1770 LYM251brachypodium|09v1|DV469153 3277 410 82.6 blastp H79 1771 LYM251canola|gb161|CN726086 3278 410 81.4 blastp H13 1772 LYM251cassava|09v1|CK650427 3279 410 80.12 tblastn H80 1773 LYM251cassava|09v1|DV448885 3280 410 81.4 blastp H81 1774 LYM251castorbean|09v1|XM002514342 3281 410 81.4 blastp H82 1775 LYM251catharanthus|gb166|EG554670 3282 410 81.4 blastp H16 1776 LYM251centaurea|gb166|EH737707 3283 410 81.4 blastp H17 1777 LYM251centaurea|gb166|EH782010 3284 410 81.4 blastp H18 1778 LYM251chestnut|gb170|SRR006295S0001854 3285 410 80.1 blastp H83 1779 LYM251chickpea|09v2|DY475463 3286 410 80.12 tblastn H84 1780 LYM251cichorium|gb171|EH677909 3287 410 81.4 blastp H85 1781 LYM251cichorium|gb171|EH681849 3288 410 80.7 blastp H86 1782 LYM251citrus|gb166|CF419015 3289 410 82 blastp H21 1783 LYM251clover|gb162|BB935136 3290 410 81.4 blastp H22 1784 LYM251cowpea|gb166|FF383763 3291 410 80.1 blastp H23 1785 LYM251cucumber|09v1|CK085508 3292 410 80.1 blastp H87 1786 LYM251dandelion|gb161|DY822878 3293 410 80.1 blastp H24 1787 LYM251eucalyptus|gb166|CT981708 3294 410 80.7 blastp H25 1788 LYM251fern|gb171|DK949355 3295 410 80.1 blastp H88 1789 LYM251fescue|gb161|DT702820 3296 410 82.6 blastp H26 1790 LYM251gerbera|09v1|AJ756319 3297 410 80.7 blastp H89 1791 LYM251grape|gb160|CB008191 3298 410 82 blastp H27 1792 LYM251grape|gb160|CD799819 3299 410 82 blastp H28 1793 LYM251ipomoea|gb157.2|CJ751066 3300 410 81.4 blastp H29 1794 LYM251jatropha|09v1|GO247140 3301 410 80.7 blastp H90 1795 LYM251lettuce|gb157.2|DW045452 3302 410 81.4 blastp H30 1796 LYM251liriodendron|gb166|CK762515 3303 410 83.2 blastp H31 1797 LYM251maize|gb170|AA979856 3304 410 83.23 tblastn H91 1798 LYM251maize|gb170|AI619342 3305 410 83.2 blastp H92 1799 LYM251maize|gb170|AW134457 3306 410 91.3 tblastn H93 1800 LYM251medicago|09v1|MSU93094 3307 410 82 blastp H94 1801 LYM251melon|gb165|DV633583 3308 410 80.1 blastp H36 1802 LYM251millet|09v1|EVO454PM010186 3309 410 83.2 blastp H95 1803 LYM251millet|09v1|EVO454PM104784 3310 410 91.93 tblastn H96 1804 LYM251monkeyflower|09v1|GR007448 3311 410 82.6 blastp H97 1805 LYM251nuphar|gb166|DT588573 3312 410 82 blastp H37 1806 LYM251oak|gb170|DN949793 3313 410 80.1 blastp H98 1807 LYM251papaya|gb165|EX261560 3314 410 81.4 blastp H38 1808 LYM251peanut|gb171|EH046845 3315 410 82 blastp H99 1809 LYM251pepper|gb171|BM068291 3316 410 83.2 blastp H100 1810 LYM251petunia|gb171|FN005056 3317 410 82.6 blastp H101 1811 LYM251pine|gb157.2|AA556857 3318 410 81.4 blastp H42 1812 LYM251pine|gb157.2|AW289837 3319 410 81.4 blastp H43 1813 LYM251poplar|gb170|AI165130 3320 410 80.1 blastp H102 1814 LYM251poppy|gb166|FG613763 3321 410 80.1 blastp H45 1815 LYM251potato|gb157.2|BF054079 3322 410 82.6 blastp H46 1816 LYM251pseudoroegneria|gb167| 3323 410 80.7 blastp H47 FF342572 1817 LYM251radish|gb164|EV525206 3324 410 80.7 blastp H48 1818 LYM251radish|gb164|EV528593 3325 410 80.7 blastp H49 1819 LYM251radish|gb164|EV534996 3326 410 81.4 blastp H50 1820 LYM251radish|gb164|EV565677 3327 410 81.4 blastp H51 1821 LYM251rice|gb170|OS03G57040 3328 410 82.6 blastp H103 1822 LYM251rye|gb164|BE637009 3329 410 80.7 blastp H53 1823 LYM251safflower|gb162|EL402398 3330 410 81.4 blastp H54 1824 LYM251 solanum3331 410 82.6 blastp H104 phureja|09v1|SPHBG126373 1825 LYM251sorghum|09v1|SB01G003840 3332 410 91.3 tblastn H105 1826 LYM251sorghum|09v1|SB01G006180 3333 410 83.2 blastp H106 1827 LYM251soybean|gb168|AW685285 3334 410 81.4 blastp H57 1828 LYM251soybean|gb168|BQ154723 3335 410 80.1 blastp H58 1829 LYM251spruce|gb162|Z93754 3336 410 80.7 blastp H59 1830 LYM251sugarcane|gb157.3|BQ533200 3337 410 83.2 blastp H107 1831 LYM251sugarcane|gb157.3|BU103624 3338 410 83.2 blastp H108 1832 LYM251sunflower|gb162|CD854801 3339 410 81.4 blastp H62 1833 LYM251sunflower|gb162|DY917387 3340 410 81.4 blastp H63 1834 LYM251sunflower|gb162|EL485634 3341 410 81.4 blastp H64 1835 LYM251switchgrass|gb167|DN152225 3342 410 83.2 blastp H65 1836 LYM251switchgrass|gb167|DN152580 3343 410 82 blastp H66 1837 LYM251switchgrass|gb167|FL827716 3344 410 92.5 blastp H67 1838 LYM251thellungiella|gb167|DN776639 3345 410 80.7 blastp H68 1839 LYM251tobacco|gb162|CV020782 3346 410 82 blastp H69 1840 LYM251tomato|09v1|BG126373 3347 410 83.2 blastp H109 1841 LYM251triphysaria|gb164|EY017996 3348 410 80.7 blastp H71 1842 LYM251walnuts|gb166|EL892983 3349 410 80.1 blastp H72 1843 LYM251walnuts|gb166|EL903496 3350 410 80.1 blastp H73 1844 LYM251wheat|gb164|BE444356 3351 410 81.4 blastp H74 1845 LYM251wheat|gb164|BE498579 3352 410 81.4 blastp H75 1846 LYM251wheat|gb164|BQ905308 3353 410 81.4 blastp H76 1847 LYM255brachypodium|09v1|DV486276 3354 413 83.9 blastp H3 1848 LYM255maize|gb170|AA072446 3355 413 80.8 blastp H4 1849 LYM255sorghum|09v1|SB04G034000 3356 413 82 blastp H5 1850 LYM255switchgrass|gb167|FE606184 3357 413 83.8 blastp H3 1851 LYM260rice|gb170|OS09G38800 3358 414 80.5 blastp H0 1852 LYM263maize|gb170|AI673859 3359 416 87.47 tblastn H0 1853 LYM183brachypodium|09v1|DV474476 3360 417 90.5 blastp H8 1853 LYM183brachypodium|09v1|DV474476 3360 464 90.5 blastp H8 1854 LYM183cenchrus|gb166|EB655853 3361 417 83.5 blastp H1 1854 LYM183cenchrus|gb166|EB655853 3361 464 83.5 blastp H1 1855 LYM183leymus|gb166|EG375719 3362 417 94.2 blastp H2 1855 LYM183leymus|gb166|EG375719 3362 464 94.2 blastp H2 1856 LYM183maize|gb170|AI964673 3363 417 85.2 blastp H9 1856 LYM183maize|gb170|AI964673 3363 464 85.2 blastp H9 1857 LYM183rice|gb170|OS03G60780 3364 417 84.8 blastp H10 1857 LYM183rice|gb170|OS03G60780 3364 464 84.8 blastp H10 1858 LYM183sorghum|09v1|SB01G003070 3365 417 84.4 blastp H11 1858 LYM183sorghum|09v1|SB01G003070 3365 464 84.4 blastp H11 1859 LYM183sugarcane|gb157.3|CA111823 3366 417 83.6 blastp H12 1859 LYM183sugarcane|gb157.3|CA111823 3366 464 83.6 blastp H12 1860 LYM183switchgrass|gb167|DN151763 3367 417 83.4 blastp H6 1860 LYM183switchgrass|gb167|DN151763 3367 464 83.4 blastp H6 1861 LYM183wheat|gb164|BE515616 3368 417 93.9 tblastn H7 1861 LYM183wheat|gb164|BE515616 3368 464 93.63 tblastn H7 1862 LYM183wheat|gb164|BQ160803 3369 417 94.7 blastp H8 1862 LYM183wheat|gb164|BQ160803 3369 464 94.7 blastp H8 1863 LYM256rice|gb170|OS05G45110 3370 418 87.3 blastp H2 1864 LYM256rice|gb170|OS10G07970 3371 418 81.09 tblastn H3 1865 LYM200sorghum|09v1|SB04G005600 3372 419 86.5 blastp H0 1866 LYM267sorghum|09v1|SB01G044240 3373 420 88.3 blastp H1 1867 LYM268sugarcane|gb157.3|CA079076 3374 421 81.6 blastp H1 1868 LYM270sorghum|09v1|SB02G040045 3375 422 82.3 blastp H0 1869 LYM271barley|gb157SOLEXA| 3376 423 89.9 blastp H7 BG344953 1870 LYM271brachypodium|09v1|GT838823 3377 423 89.9 blastp H8 1871 LYM271rice|gb170|OS07G43460 3378 423 91.1 blastp H9 1872 LYM271sorghum|09v1|SB02G040020 3379 423 96.5 blastp H10 1873 LYM271sugarcane|gb157.3|CA118167 3380 423 89.53 tblastn H11 1874 LYM271switchgrass|gb167|FL691032 3381 423 94.2 blastp H6 1875 LYM271wheat|gb164|CJ664209 3382 423 91.5 blastp H7 1876 LYM273brachypodium|09v1|DV469687 3383 425 83.3 blastp H4 1877 LYM273maize|gb170|AW355978 3384 425 85.2 blastp H5 1878 LYM273sorghum|09v1|SB03G044410 3385 425 84 blastp H6 1879 LYM273wheat|gb164|BE518377 3386 425 85 blastp H4 1880 LYM274rice|gb170|OS01G70240 3387 426 100 blastp H0 1880 LYM274rice|gb170|OS01G70240 3387 466 89.2 blastp H0 1881 LYM278maize|gb170|LLDQ244681 3388 428 95.2 blastp H9 1882 LYM278rye|gb164|Z23257 3389 428 92.86 tblastn H2 1883 LYM278wheat|gb164|AL821264 3390 428 95.3 blastp H3 1884 LYM278wheat|gb164|BE516723 3391 428 94 blastp H4 1885 LYM278wheat|gb164|BF200402 3392 428 86.9 tblastn H5 1886 LYM278wheat|gb164|BF474423 3393 428 92.86 tblastn H6 1887 LYM278wheat|gb164|BG909462 3394 428 89.3 blastp H7 1888 LYM278wheat|gb164|BQ579097 3395 428 95.24 tblastn H8 1889 LYM278wheat|gb164|CA650349 3396 428 83.3 blastp H9 1890 LYM284barley|gb157SOLEXA| 3397 430 86.4 blastp H16 BE438857 1891 LYM284brachypodium|09v1|DV474685 3398 430 84.3 blastp H17 1892 LYM284brachypodium|09v1|DV488161 3399 430 88.2 blastp H18 1893 LYM284fescue|gb161|DT674446 3400 430 86.91 tblastn H3 1894 LYM284maize|gb170|AI637256 3401 430 88.5 blastp H19 1895 LYM284maize|gb170|AI861131 3402 430 84.3 blastp H20 1896 LYM284maize|gb170|BM501276 3403 430 83.8 blastp H21 1897 LYM284rice|gb170|OS01G43020 3404 430 81.4 blastp H22 1898 LYM284rice|gb170|OS01G46570 3405 430 84.6 blastp H23 1899 LYM284sorghum|09v1|SB03G027960 3406 430 80.6 blastp H24 1900 LYM284sorghum|09v1|SB03G029790 3407 430 85.1 blastp H25 1901 LYM284sorghum|09v1|SB09G029130 3408 430 87.2 blastp H26 1902 LYM284sugarcane|gb157.3|BQ533889 3409 430 84.5 blastp H27 1903 LYM284switchgrass|gb167|DN151636 3410 430 81 blastp H12 1904 LYM284switchgrass|gb167|FE634580 3411 430 85.4 blastp H13 1905 LYM284switchgrass|gb167|FL712120 3412 430 89.53 tblastn H14 1906 LYM284wheat|gb164|BE400789 3413 430 88.1 blastp H15 1907 LYM284wheat|gb164|BF200804 3414 430 80.4 blastp H16 1908 LYM285brachypodium|09v1|DV476342 3415 431 89.2 blastp H3 1909 LYM285maize|gb170|AI372298 3416 431 88.1 blastp H4 1910 LYM285rice|gb170|OS01G69900 3417 431 99.82 tblastn H5 1911 LYM285sorghum|09v1|SB03G044210 3418 431 89.3 blastp H6 1912 LYM285switchgrass|gb167|DN142770 3419 431 89.75 tblastn H3 1913 LYM288brachypodium|09v1|DV471350 3420 433 83.3 blastp H6 1914 LYM288leymus|gb166|EG377996 3421 433 84.7 blastp H1 1915 LYM288maize|gb170|AI977924 3422 433 84.5 blastp H7 1916 LYM288sorghum|09v1|SB02G039240 3423 433 83.9 blastp H8 1917 LYM288sugarcane|gb157.3|CA067537 3424 433 85.8 blastp H9 1918 LYM288switchgrass|gb167|DN151710 3425 433 85.3 blastp H5 1919 LYM288switchgrass|gb167|FE610990 3426 433 85.3 blastp H6 1920 LYM289barley|gb157SOLEXA| 3427 434 91.1 blastp H39 AL500321 1921 LYM289barley|gb157SOLEXA| 3428 434 92.7 blastp H40 AV915627 1922 LYM289barley|gb157SOLEXA| 3429 434 98.2 blastp H41 BF624195 1923 LYM289barley|gb157SOLEXA| 3430 434 92.7 blastp H42 BF627133 1924 LYM289barley|gb157SOLEXA| 3431 434 92.7 blastp H43 BQ739963 1925 LYM289brachypodium|09v1|GFXEF059989X41 3432 434 81.8 blastp H44 1926 LYM289cacao|gb167|CU568933 3433 434 85.5 blastp H7 1927 LYM289fescue|gb161|CK801501 3434 434 90.9 blastp H8 1928 LYM289fescue|gb161|DT683663 3435 434 90.9 blastp H9 1929 LYM289leymus|gb166|EG376287 3436 434 96.4 blastp H10 1930 LYM289lolium|09v1|AU246683 3437 434 89.1 blastp H45 1931 LYM289lovegrass|gb167|DN480351 3438 434 87.3 blastp H11 1932 LYM289maize|gb170|AI637242 3439 434 81.8 blastp H46 1933 LYM289maize|gb170|LLEC865320 3440 434 81.8 blastp H47 1934 LYM289maize|gb170|T12715 3441 434 87.3 blastp H48 1935 LYM289millet|09v1|CD724594 3442 434 80 blastp H49 1936 LYM289millet|09v1|EB410971 3443 434 87.3 blastp H50 1937 LYM289oat|gb164|CN818354 3444 434 90.9 blastp H15 1938 LYM289pineapple|gb157.2|DT337702 3445 434 80 blastp H16 1939 LYM289rice|gb170|OS06G05120 3446 434 83.6 blastp H51 1940 LYM289sorghum|09v1|SB09G005410 3447 434 80 blastp H52 1941 LYM289sorghum|09v1|SB10G002980 3448 434 87.3 blastp H53 1942 LYM289sugarcane|gb157.3|CA117495 3449 434 87.3 blastp H54 1943 LYM289sugarcane|gb157.3|CA149658 3450 434 81.8 blastp H55 1944 LYM289sugarcane|gb157.3|CF575668 3451 434 87.3 blastp H56 1945 LYM289switchgrass|gb167|DN144776 3452 434 80 blastp H23 1946 LYM289switchgrass|gb167|DN144989 3453 434 89.1 blastp H24 1947 LYM289switchgrass|gb167|FE607508 3454 434 89.1 blastp H25 1948 LYM289switchgrass|gb167|FL736037 3455 434 81.8 blastp H26 1949 LYM289wheat|gb164|AL811119 3456 434 98.2 blastp H27 1950 LYM289wheat|gb164|BE443789 3457 434 96.4 blastp H28 1951 LYM289wheat|gb164|BG907098 3458 434 98.2 blastp H29 1952 LYM289wheat|gb164|BM136571 3459 434 96.4 blastp H30 1953 LYM289wheat|gb164|BQ804261 3460 434 96.4 blastp H31 1954 LYM289wheat|gb164|CA616586 3461 434 81.8 blastp H32 1955 LYM289wheat|gb164|CA640178 3462 434 98.2 blastp H33 1956 LYM289wheat|gb164|CA643784 3463 434 98.2 blastp H34 1957 LYM289wheat|gb164|CA733972 3464 434 80.36 tblastn H35 1958 LYM289wheat|gb164|CD896873 3465 434 82.1 blastp H36 1959 LYM289wheat|gb164|CJ586709 3466 434 89.1 blastp H37 1960 LYM289wheat|gb164|CJ646970 3467 434 80 blastp H38 1961 LYM289wheat|gb164|CJ903378 3468 434 96.4 blastp H39 1962 LYM290barley|gb157SOLEXA| 3469 435 82.9 blastp H10 BE412989 1963 LYM290brachypodium|09v1|GT759831 3470 435 81.9 blastp H11 1964 LYM290rice|gb170|OS04G20230 3471 435 82.9 blastp H12 1965 LYM290rye|gb164|BE495099 3472 435 81.9 blastp H3 1966 LYM290sorghum|09v1|SB01G009390 3473 435 95.2 blastp H13 1967 LYM290sorghum|09v1|SB06G004500 3474 435 94.8 blastp H14 1968 LYM290sugarcane|gb157.3|BQ535968 3475 435 95.7 blastp H15 1969 LYM290sugarcane|gb157.3|CA136629 3476 435 80.3 blastp H16 1970 LYM290switchgrass|gb167|FE622978 3477 435 91.4 blastp H8 1971 LYM290wheat|gb164|BE430090 3478 435 83.3 blastp H9 1972 LYM290wheat|gb164|BF199524 3479 435 82.4 blastp H10 1973 LYM293rice|gb170|OS09G38510 3480 437 91.8 blastp H0 Table 2: Provided are thehomologous polypeptides and polynucleotides of the genes for increasingyield (e.g., oil yield, seed yield, fiber yield and/or quality), growthrate, vigor, biomass, abiotic stress tolerance, nitrogen use efficiency,water use efficiency and fertilizer use efficiency genes of a plantwhich are listed in Table 1 above. Homology was calculated as % ofidentity over the aligned sequences. The query sequences werepolynucleotide sequences SEQ ID NOs: 1-239 and polypeptide SEQ ID NOs:240-465 and the subject sequences are protein sequences identified inthe database based on greater than 80% identity to the predictedtranslated sequences of the query nucleotide sequences or to thepolypeptide sequences. “Nucl.” = polynucleotide; “polyp.” = polypeptide;“Algor.” = algorithm (used for sequence alignment and determination ofpercent homology).

The following sequences were found to be 100% identical: SEQ ID NO: 4 isidentical to SEQ ID NO: 478; SEQ ID NO: 24 is identical to SEQ ID NO:914; SEQ ID NO: 79 is identical to SEQ ID NO: 1050; SEQ ID NO: 132 isidentical to SEQ ID NO: 3608; SEQ ID NO: 163 is identical to SEQ ID NO:1734; SEQ ID NO: 249 is identical to SEQ ID NO: 2100, 2101, 2103, and2108; SEQ ID NO: 321 is identical to SEQ ID NO: 2771; SEQ ID NO: 382 isidentical to SEQ ID NO: 3019; SEQ ID NO: 387 is identical to SEQ ID NO:2945; SEQ ID NO426 is identical to SEQ ID NO: 3387; SEQ ID NO: 446 isidentical to SEQ ID NO: 2946; SEQ ID NO: 449 is identical to SEQ ID NO:3705; SEQ ID NO: 2005 is identical to SEQ ID NO: 2011 and 2012; SEQ IDNO: 2007 is identical to SEQ ID NO: 2043 and 2045; SEQ ID NO: 2038 isidentical to SEQ ID NO: 2039; SEQ ID NO: 2071 is identical to SEQ ID NO:2072; SEQ ID NO: 2075 is identical to SEQ ID NO:2076, 2078, 2079, 2083,2084, 2086, 2089, 2090, 2092, 2093, 2095, 2120, 2122, 2235, 2236, 2238,2239, 2277, and 2278; SEQ ID NO: 2080 is identical to SEQ ID NO: 2155,2176, 2179, 2248, and 2268; SEQ ID NO: 2102 is identical to SEQ ID NO:2193; SEQ ID NO: 2105 is identical to SEQ ID NO: 2147, 2181, 2196, 2197,2210, 2211, 2213, 2254, and 2256; SEQ ID NO: 2125 is identical to SEQ IDNO: 2126 and 2127; SEQ ID NO: 2130 is identical to SEQ ID NO: 2131,2214, 2228, 2231, and 2251; SEQ ID NO: 2134 is identical to SEQ ID NO:2247; SEQ ID NO: 2144 is identical to SEQ ID NO: 2153 and 2201; SEQ IDNO: 2188 is identical to SEQ ID NO: 2191, 2253, 2264, and 2271; SEQ IDNO: 2189 is identical to SEQ ID NO: 2202, 2252, 2265, 2266, 2270, and2272; SEQ ID NO: 2215 is identical to SEQ ID NO: 2250 and 2284; SEQ IDNO: 2218 is identical to SEQ ID NO: 2219; SEQ ID NO: 2220 is identicalto SEQ ID NO: 2221 and 2258; SEQ ID NO: 2356 is identical to SEQ ID NO:2357 and 2359; SEQ ID NO: 2380 is identical to SEQ ID NO: 2402; SEQ IDNO: 2384 is identical to SEQ ID NO: 2387; SEQ ID NO: 2463 is identicalto SEQ ID NO:2464; SEQ ID NO: 2481 is identical to SEQ ID NO: 2483; SEQID NO: 2485 is identical to SEQ ID NO: 2486; SEQ ID NO: 2533 isidentical to SEQ ID NO: 2538; SEQ ID NO: 2582 is identical to SEQ ID NO:2583; SEQ ID NO: 2588 is identical to SEQ ID NO: 2594, 2603, 2621, and2629; SEQ ID NO: 2589 is identical to SEQ ID NO:2590, 2591, 2592, 2595,2596, 2601, 2604, 2605, 2623, 2624, 2626, 2627, 2630, 2756, 2757, 2758,2760, 2761, 2762, 2764, 2765, and 2807; SEQ ID NO:2593 is identical toSEQ ID NO:2632, and 2767; SEQ ID NO: 2600 is identical to SEQ ID NO:2622; SEQ ID NO: 2606 is identical to SEQ ID NO: 2610; SEQ ID NO: 2607is identical to SEQ ID NO: 2609; SEQ ID NO: 2625 is identical to SEQ IDNO: 2713; SEQ ID NO: 2638 is identical to SEQ ID NO: 2639; SEQ ID NO:2644 is identical to SEQ ID NO: 2727; SEQ ID NO: 2645 is identical toSEQ ID NO: 2726; SEQ ID NO: 2665 is identical to SEQ ID NO: 2719; SEQ IDNO: 2687 is identical to SEQ ID NO: 2689; SEQ ID NO: 2691 is identicalto SEQ ID NO: 2693 and 2698; SEQ ID NO: 2694 is identical to SEQ ID NO:2697; SEQ ID NO: 2712 is identical to SEQ ID NO: 2816, 2817 and 2818;SEQ ID NO: 2748 is identical to SEQ ID NO: 2749, 2778 and 2815; SEQ IDNO: 2750 is identical to SEQ ID NO: 2751 and 2776; SEQ ID NO: 2779 isidentical to SEQ ID NO: 2790 and 2794; SEQ ID NO: 2801 is identical toSEQ ID NO: 2804; SEQ ID NO: 2873 is identical to SEQ ID NO: 2880; SEQ IDNO: 2876 is identical to SEQ ID NO: 2881; SEQ ID NO: 2877 is identicalto SEQ ID NO: 2879; SEQ ID NO: 2908 is identical to SEQ ID NO: 2909; SEQID NO: 3135 is identical to SEQ ID NO: 3136; SEQ ID NO: 3138 isidentical to SEQ ID NO: 3145; SEQ ID NO: 3268 is identical to SEQ ID NO:3271, 3272, 3278, 3326, and 3327; SEQ ID NO: 3274 is identical to SEQ IDNO: 3351, 3352, and 3353; SEQ ID NO: 3277 is identical to SEQ ID NO:3296; SEQ ID NO: 3285 is identical to SEQ ID NO: 3313; SEQ ID NO: 3287is identical to SEQ ID NO: 3302; SEQ ID NO: 3309 is identical to SEQ IDNO: 3333, 3337, 3338, and 3342; SEQ ID NO: 3318 is identical to SEQ IDNO: 3319; SEQ ID NO: 3322 is identical to SEQ ID NO: 3331; SEQ ID NO:3428 is identical to SEQ ID NO: 3430 3431; SEQ ID NO: 3434 is identicalto SEQ ID NO: 3435; SEQ ID NO: 3439 is identical to SEQ ID NO: 3440 and3461; SEQ ID NO: 3448 is identical to SEQ ID NO: 3449 and 3451; SEQ IDNO: 3453 is identical to SEQ ID NO: 3454; SEQ ID NO: 3456 is identicalto SEQ ID NO: 3458, 3462 and 3463; SEQ ID NO: 3457 is identical to SEQID NO: 3459 and 3468;

The output of the functional genomics approach described herein is a setof genes highly predicted to improve yield and/or other agronomicimportant traits such as growth rate, vigor, oil content, fiber yieldand/or quality, biomass, growth rate, abiotic stress tolerance, nitrogenuse efficiency, water use efficiency and fertilizer use efficiency of aplant by increasing their expression. Although each gene is predicted tohave its own impact, modifying the mode of expression of more than onegene is expected to provide an additive or synergistic effect on theplant yield and/or other agronomic important yields performance.Altering the expression of each gene described here alone or set ofgenes together increases the overall yield and/or other agronomicimportant traits, hence expects to increase agricultural productivity.

Example 3 Production of Barley Transcriptom and High ThroughputCorrelation Analysis Using 44K Barley Oligonucleotide Micro-Array

In order to produce a high throughput correlation analysis, the presentinventors utilized a Barley oligonucleotide micro-array, produced byAgilent Technologies [Hypertext Transfer Protocol://World Wide Web (dot)chem. (dot) agilent (dot) com/Scripts/PDS (dot) asp?1Page=50879]. Thearray oligonucleotide represents about 47,500 Barley genes andtranscripts. In order to define correlations between the levels of RNAexpression and yield or vigor related parameters, various plantcharacteristics of 25 different Barley accessions were analyzed. Amongthem, 13 accessions encompassing the observed variance were selected forRNA expression analysis. The correlation between the RNA levels and thecharacterized parameters was analyzed using Pearson correlation test[Hypertext Transfer Protocol://World Wide Web (dot) davidmlane (dot)com/hyperstat/A34739 (dot) html].

Experimental Procedures

RNA extraction—Five tissues at different developmental stages [meristem,flower, booting spike, stem, flag leaf], representing different plantcharacteristics, were sampled and RNA was extracted using TRIzol Reagentfrom Invitrogen [Hypertext Transfer Protocol://World Wide Web (dot)invitrogen (dot) com/content (dot)cfm?pageid=469]. Approximately 30-50mg of tissue was taken from samples. The weighed tissues were groundusing pestle and mortar in liquid nitrogen and resuspended in 500 μl ofTRIzol Reagent. To the homogenized lysate, 100 μl of chloroform wasadded followed by precipitation using isopropanol and two washes with75% ethanol. The RNA was eluted in 30 μl of RNase-free water. RNAsamples were cleaned up using Qiagen's RNeasy minikit clean-up protocolas per the manufacturer's protocol (QIAGEN Inc, CA USA).

For convenience, each micro-array expression information tissue type hasreceived a Set ID as summarized in Table 3 below.

TABLE 3 Barley transcriptom expression sets Expression Set Set IDMeristem A Flower B Booting spike C Stem D Flag leaf E Table 3

Barley yield components and vigor related parameters assessment—25Barley accessions in 4 repetitive blocks (named A, B, C, and D), eachcontaining 4 plants per plot were grown at net house. Plants werephenotyped on a daily basis following the standard descriptor of barley(Table 4, below). Harvest was conducted while 50% of the spikes were dryto avoid spontaneous release of the seeds. Plants were separated to thevegetative part and spikes, of them, 5 spikes were threshed (grains wereseparated from the glumes) for additional grain analysis such as sizemeasurement, grain count per spike and grain yield per spike. Allmaterial was oven dried and the seeds were threshed manually from thespikes prior to measurement of the seed characteristics (weight andsize) using scanning and image analysis. The image analysis systemincluded a personal desktop computer (Intel P4 3.0 GHz processor) and apublic domain program—Image J 1.37 (Java based image processing program,which was developed at the U.S. National Institutes of Health and freelyavailable on the internet [Hypertext Transfer Protocol://rsbweb (dot)nih (dot) gov/]. Next, analyzed data was saved to text files andprocessed using the JMP statistical analysis software (SAS institute).

TABLE 4 Barley standard descriptors Trait Parameter Range DescriptionGrowth habit Scoring 1-9 Prostrate (1) or Erect (9) Hairiness of basalScoring P (Presence)/ Absence (1) leaves A (Absence) or Presence (2)Stem Scoring 1-5 Green (1), Basal pigmentation only or Half or more (5)Days to Days Days from sowing Flowering to emergence of awns Plantheight Centimeter (cm) Height from ground level to top of the longestspike excluding awns Spikes per plant Number Terminal Counting Spikelength Centimeter (cm) Terminal Counting 5 spikes per plant Grains perspike Number Terminal Counting 5 spikes per plant Vegetative dry GramOven-dried for weight 48 hours at 70° C. Spikes dry weight GramOven-dried for 48 hours at 30° C. Table 4.

Grains per spike—At the end of the experiment (50% of the spikes weredry) all spikes from plots within blocks A-D are collected. The totalnumber of grains from 5 spikes that were manually threshed was counted.The average grain per spike is calculated by dividing the total grainnumber by the number of spikes.

Grain average size (cm)—At the end of the experiment (50% of the spikeswere dry) all spikes from plots within blocks A-D are collected. Thetotal grains from 5 spikes that were manually threshed were scanned andimages were analyzed using the digital imaging system. Grain scanningwas done using Brother scanner (model DCP-135), at the 200 dpiresolution and analyzed with Image J software. The average grain sizewas calculated by dividing the total grain size by the total grainnumber.

Grain average weight (mgr)—At the end of the experiment (50% of thespikes were dry) all spikes from plots within blocks A-D are collected.The total grains from 5 spikes that were manually threshed were countedand weight. The average weight was calculated by dividing the totalweight by the total grain number.

Grain yield per spike (gr)—At the end of the experiment (50% of thespikes were dry) all spikes from plots within blocks A-D are collected.The total grains from 5 spikes that were manually threshed were weight.The grain yield was calculated by dividing the total weight by the spikenumber.

Spike length analysis—At the end of the experiment (50% of the spikeswere dry) all spikes from plots within blocks A-D are collected. Thefive chosen spikes per plant were measured using measuring tapeexcluding the awns.

Spike number analysis—At the end of the experiment (50% of the spikeswere dry) all spikes from plots within blocks A-D are collected. Thespikes per plant were counted.

Growth habit scoring—At the growth stage 10 (booting), each of theplants was scored for its growth habit nature. The scale that was usedwas 1 for prostate nature till 9 for erect.

Hairiness of basal leaves—At the growth stage 5 (leaf sheath stronglyerect; end of tillering), each of the plants was scored for itshairiness nature of the leaf before the last. The scale that was usedwas 1 for prostate nature till 9 for erect.

Plant height—At the harvest stage (50% of spikes were dry) each of theplants was measured for its height using measuring tape. Height wasmeasured from ground level to top of the longest spike excluding awns.

Days to flowering—Each of the plants was monitored for flowering date.Days of flowering was calculated from sowing date till flowering date.

Stem pigmentation—At the growth stage 10 (booting), each of the plantswas scored for its stem color. The scale that was used was 1 for greentill 5 for full purple.

Vegetative dry weight and spike yield—At the end of the experiment (50%of the spikes were dry) all spikes and vegetative material from plotswithin blocks A-D are collected. The biomass and spikes weight of eachplot was separated, measured and divided by the number of plants.

Dry weight=total weight of the vegetative portion above ground(excluding roots) after drying at 70° C. in oven for 48 hours;

Spike yield per plant=total spike weight per plant (gr) after drying at30° C. in oven for 48 hours.

Harvest Index (for barley)—The harvest index is calculated using FormulaVI.Harvest Index=Average spike dry weight per plant/(Average vegetative dryweight per plant+Average spike dry weight per plant)  Formula VI

TABLE 5 Barley correlated parameters (vectors) Correlated parameter with(units) Correlation Id Grains per spike (numbers) 1 Grains size (mm²) 2Grain weight (miligrams) 3 Grain Yield per spike (gr/spike) 4 Spikelength (cm) 5 Spikes per plant (numbers) 6 Growth habit (scores 1-9) 7Hairiness of basal leaves (scoring 1-2) 8 Plant height (cm) 9 Days toflowering (days) 10 Stem pigmentation (scoring 1-5) 11 Vegetative dryweight (gram) 12 Harvest Index (ratio) 13 Table 5.

Experimental Results

13 different Barley accessions were grown and characterized for 13parameters as described above. The average for each of the measuredparameter was calculated using the JMP software and values aresummarized in Tables 6 and 7 below. Subsequent correlation analysisbetween the various transcriptom sets (Table 3) and the averageparameters, was conducted. Follow, results were integrated to thedatabase.

TABLE 6 Measured parameters of correlation Ids in Barley accessionsAccession/ Parameter 6 10 3 5 2 1 7 Amatzya 48.85 62.40 35.05 12.04 0.2720.23 2.60 Ashqelon 48.27 64.08 28.06 10.93 0.23 17.98 2.00 Canada park37.42 65.15 28.76 11.83 0.24 17.27 1.92 Havarim stream 61.92 58.92 17.879.90 0.17 17.73 3.17 Jordan est 33.27 63.00 41.22 11.68 0.29 14.47 4.33Klil 41.69 70.54 29.73 11.53 0.28 16.78 2.69 Maale Efraim ND 52.80 25.228.86 0.22 13.47 3.60 Mt Arbel 40.63 60.88 34.99 11.22 0.28 14.07 3.50 MtHarif 62.00 58.10 20.58 11.11 0.19 21.54 3.00 Neomi 49.33 53.00 27.508.58 0.22 12.10 3.67 Neot Kdumim 50.60 60.40 37.13 10.18 0.27 14.36 2.47Oren canyon 43.09 64.58 29.56 10.51 0.27 15.28 3.50 Yeruham 51.40 56.0019.58 9.80 0.18 17.07 3.00 Table 6. Provided are the values of each ofthe parameters measured in Barley accessions according to the followingcorrelation identifications (Correlation Ids): 6 = Spikes per plant; 10= Days to flowering; 3 = Grain weight; 5 = Spike length; 2 = GrainsSize; 1 = Grains per spike; 7 = Growth habit.

TABLE 7 Barley accessions, additional measured parameters Accession/Parameter 8 9 4 11 12 13 Amatzya 1.53 134.27 3.56 1.13 78.87 0.45Ashqelon 1.33 130.50 2.54 2.50 66.14 0.42 Canada park 1.69 138.77 2.581.69 68.49 0.40 Havarim stream 1.08 114.58 1.57 1.75 53.39 0.44 Jordanest 1.42 127.75 3.03 2.33 68.30 0.43 Klil 1.69 129.38 2.52 2.31 74.170.40 Maale Efraim 1.30 103.89 1.55 1.70 35.35 0.52 Mt Arbel 1.19 121.632.62 2.19 58.33 0.48 Mt Harif 1.00 126.80 2.30 2.30 62.23 0.44 Neomi1.17 99.83 1.68 1.83 38.32 0.49 Neot Kdumim 1.60 121.40 2.68 3.07 68.310.45 Oren canyon 1.08 118.42 2.35 1.58 56.15 ND Yeruham 1.17 117.17 1.672.17 42.68 ND Table 7. Provided are the values of each of the parametersmeasured in Barley accessions according to the following correlationidentifications (Correlation Ids): 8 = Hairiness of basal leaves; 9 =Plant height; 4 = Grain yield per spike; 11 = Stem pigmentation; 12 =Vegetative dry weight; 13 = Harvest Index.

TABLE 8 Correlation between the expression level of the selectedpolynucleotides of the invention and their homologues in specifictissues or developmental stages and the phenotypic performance acrossBarley ecotypes Gene Name Expression Set Correlation Vector R P LYM26 A12 0.87938 0.00178 LYM26 A 4 0.86421 0.00265 LYM26 A 12 0.85977 0.00069LYM26 A 4 0.84991 0.00092 LYM26 A 9 0.83315 0.00145 LYM26 A 9 0.819300.00689 LYM26 A 5 0.81231 0.00238 LYM26 A 5 0.80624 0.00867 LYM26 C 10.74897 0.00799 LYM26 C 1 0.73316 0.02461 LYM26 A 10 0.72560 0.02691LYM51 A 10 0.93629 0.00020 LYM51 A 12 0.92036 0.00043 LYM51 A 5 0.886790.00144 LYM51 A 9 0.87500 0.00201 LYM51 A 10 0.85681 0.00075 LYM51 A 40.82050 0.00674 LYM51 A 5 0.78204 0.00445 LYM51 A 9 0.77050 0.00552LYM51 A 12 0.74603 0.00838 LYM51 A 4 0.71036 0.01430 LYM59 A 4 0.889390.00133 LYM59 A 3 0.80853 0.00834 LYM59 A 2 0.80307 0.00915 LYM59 A 120.79319 0.01075 LYM59 A 5 0.73433 0.02426 LYM59 A 10 0.72556 0.02693LYM66 A 1 0.77697 0.01376 LYM66 A 1 0.75508 0.00722 LYM82 A 10 0.887600.00140 LYM82 A 12 0.86378 0.00061 LYM82 A 12 0.85529 0.00329 LYM82 A 100.84623 0.00102 LYM82 A 9 0.83000 0.00562 LYM82 A 9 0.82602 0.00173LYM82 A 4 0.81534 0.00222 LYM82 A 4 0.79017 0.01127 LYM82 A 5 0.784670.00424 LYM82 A 5 0.76164 0.01709 LYM84 C 2 0.79418 0.01058 LYM84 B 20.79145 0.01928 LYM84 C 3 0.77694 0.01377 LYM84 B 3 0.75502 0.03033LYM84 A 2 0.70823 0.01473 LYM99 C 7 0.75021 0.01989 LYM99 A 7 0.722940.02776 LYM95 B 2 0.81158 0.00436 LYM95 B 3 0.77615 0.00830 LYM95 B 100.73186 0.01612 LYM95 C 2 0.72471 0.02719 LYM95 B 5 0.71170 0.02097LYM100 A 3 0.77258 0.01467 LYM100 A 4 0.76559 0.01619 LYM100 A 2 0.726280.02670 LYM105 A 4 0.80126 0.00943 LYM105 A 2 0.80060 0.00953 LYM105 A 30.78770 0.01171 LYM105 A 8 0.71795 0.02939 LYM105 B 1 0.71160 0.04775LYM137 C 5 0.91789 0.00007 LYM137 C 4 0.87211 0.00046 LYM137 C 100.86290 0.00063 LYM137 C 12 0.85934 0.00070 LYM137 C 9 0.82372 0.00183LYM137 C 3 0.73788 0.02323 LYM137 C 2 0.71562 0.03017 LYM140 C 6 0.836230.00968 LYM142 B 6 0.85850 0.01338 LYM142 A 4 0.80126 0.00943 LYM142 A 20.80060 0.00953 LYM142 A 3 0.78770 0.01171 LYM142 A 8 0.73208 0.01042LYM142 A 8 0.71795 0.02939 LYM142 B 1 0.71160 0.04775 LYM148 A 4 0.798870.00318 LYM148 A 12 0.76743 0.00583 LYM148 A 4 0.76342 0.01668 LYM148 A9 0.74349 0.00873 LYM148 A 5 0.70612 0.01516 LYM149 B 7 0.75092 0.03177LYM156 C 2 0.79406 0.00352 LYM156 C 2 0.77724 0.01371 LYM156 A 2 0.767120.00586 LYM156 A 3 0.73707 0.00965 LYM156 C 3 0.71152 0.01407 LYM156 B 30.70014 0.05315 LYM157 A 4 0.78681 0.01187 LYM157 A 3 0.73234 0.02485LYM157 A 12 0.72729 0.02639 LYM160 A 12 0.87825 0.00184 LYM160 A 100.82699 0.00596 LYM160 A 12 0.82567 0.00174 LYM160 A 9 0.80855 0.00834LYM160 A 9 0.80222 0.00297 LYM160 A 10 0.74770 0.00815 LYM160 A 50.72266 0.02785 LYM160 A 5 0.71752 0.01292 LYM154 C 2 0.92810 0.00004LYM154 C 3 0.90313 0.00014 LYM154 C 4 0.85169 0.00088 LYM154 C 5 0.735380.00991 LYM154 C 10 0.71818 0.01280 LYM154 C 12 0.70985 0.01440 LYM155 C6 0.72312 0.04266 LYM155 C 1 0.70598 0.01519 LYM180 C 1 0.76320 0.00628LYM180 B 6 0.75133 0.05153 LYM181 C 6 0.78450 0.02115 LYM184 B 6 0.823950.02266 LYM184 B 6 0.73704 0.01501 LYM189 A 10 0.81585 0.00733 LYM189 A12 0.81256 0.00777 LYM189 A 9 0.72388 0.02746 LYM189 A 5 0.71589 0.03008LYM192 A 2 0.86386 0.00061 LYM192 A 3 0.80919 0.00255 LYM192 A 3 0.776120.01393 LYM278 A 4 0.90217 0.00088 LYM278 A 4 0.87108 0.00048 LYM278 A12 0.81518 0.00742 LYM278 A 3 0.79925 0.00975 LYM278 A 3 0.78102 0.00454LYM278 A 12 0.76569 0.00601 LYM278 A 2 0.73983 0.00925 LYM38 A 4 0.976240.00001 LYM38 A 12 0.82191 0.00191 LYM38 A 8 0.82190 0.00656 LYM38 A 30.82153 0.00193 LYM38 A 5 0.81079 0.00246 LYM52 B 8 0.88462 0.00352LYM52 A 2 0.80812 0.00261 LYM52 A 4 0.80802 0.00841 LYM52 A 3 0.783400.01251 LYM52 A 12 0.77364 0.01444 LYM52 A 9 0.75221 0.01938 LYM52 A 50.74914 0.02016 LYM52 A 8 0.71086 0.03181 LYM56 A 3 0.85797 0.00073LYM56 A 4 0.85130 0.00089 LYM56 A 2 0.82071 0.00196 LYM56 A 8 0.762360.01692 LYM56 A 12 0.72510 0.01157 LYM83 A 9 0.87556 0.00198 LYM83 A 50.87005 0.00050 LYM83 A 12 0.82187 0.00191 LYM90 C 4 0.86848 0.00238LYM90 C 3 0.81261 0.00777 LYM90 C 12 0.77921 0.01332 LYM90 C 2 0.765120.01629 LYM93 A 9 0.86630 0.00056 LYM93 A 12 0.78696 0.00405 LYM93 A 50.76542 0.00604 LYM106 A 3 0.79483 0.01047 LYM106 A 2 0.75674 0.01825LYM106 C 6 0.73962 0.03596 LYM159 C 1 0.82807 0.00584 LYM159 B 8 0.793560.01873 LYM161 C 3 0.89287 0.00119 LYM161 C 2 0.88206 0.00165 LYM161 A 60.85373 0.00699 LYM161 C 4 0.74623 0.02093 LYM178 C 6 0.83756 0.00945LYM182 A 6 0.93567 0.00063 LYM185 C 4 0.76455 0.01642 LYM185 A 1 0.759520.01759 LYM185 A 6 0.70292 0.01584 LYM186 A 6 0.86003 0.00616 LYM188 A 60.82774 0.00166 LYM188 C 2 0.73602 0.02377 LYM188 C 3 0.71072 0.03186LYM194 A 2 0.89053 0.00024 LYM194 A 3 0.82982 0.00157 LYM289 A 9 0.776090.01394 LYM289 A 5 0.77182 0.01483 Table 8. Provided are thecorrelations (R) and p-values (P) between the expression levels ofselected genes of some embodiments of the invention in various tissuesor developmental stages (Expression sets) and the phenotypic performancein various yield (seed yield, oil yield, oil content), biomass, growthrate and/or vigor components [Correlation (Corr.) vector (Vec.)] Corr.Vec. = correlation vector specified in Tables 5, 6 and 7; Exp. Set =expression set specified in Table 3.

Example 4 Production of Arabidopsis Transcriptom and High ThroughputCorrelation Analysis of Yield, Biomass and/or Vigor Related ParametersUsing 44K Arabidopsis Full Genome Oligonucleotide Micro-Array

To produce a high throughput correlation analysis, the present inventorsutilized an Arabidopsis thaliana oligonucleotide micro-array, producedby Agilent Technologies [Hypertext Transfer Protocol://World Wide Web(dot) chem. (dot) agilent (dot) com/Scripts/PDS (dot) asp?1Page=50879].The array oligonucleotide represents about 40,000 A. thaliana genes andtranscripts designed based on data from the TIGR ATH1 v.5 database andArabidopsis MPSS (University of Delaware) databases. To definecorrelations between the levels of RNA expression and yield, biomasscomponents or vigor related parameters, various plant characteristics of15 different Arabidopsis ecotypes were analyzed. Among them, nineecotypes encompassing the observed variance were selected for RNAexpression analysis. The correlation between the RNA levels and thecharacterized parameters was analyzed using Pearson correlation test[Hypertext Transfer Protocol://World Wide Web (dot) davidmlane (dot)com/hyperstat/A34739 (dot) html].

Experimental Procedures

RNA extraction—Five tissues at different developmental stages includingroot, leaf, flower at anthesis, seed at 5 days after flowering (DAF) andseed at 12 DAF, representing different plant characteristics, weresampled and RNA was extracted as described in Example 3 above. Forconvenience, each micro-array expression information tissue type hasreceived a Set ID as summarized in Table 9 below.

TABLE 9 Tissues used for Arabidopsis transcriptom expression setsExpression Set Set ID Root A Leaf B Flower C Seed 5 DAF D Seed 12 DAF ETable 9: Provided are the identification (ID) letters of each of theArabidopsis expression sets (A-E). DAF = days after flowering.

Yield components and vigor related parameters assessment—eight out ofthe nine Arabidopsis ecotypes were used in each of 5 repetitive blocks(named A, B, C, D and E), each containing 20 plants per plot. The plantswere grown in a greenhouse at controlled conditions in 22° C., and theN:P:K fertilizer (20:20:20; weight ratios) [nitrogen (N), phosphorus (P)and potassium (K)] was added. During this time data was collected,documented and analyzed. Additional data was collected through theseedling stage of plants grown in a tissue culture in vertical growntransparent agar plates. Most of chosen parameters were analyzed bydigital imaging.

Digital imaging in Tissue culture—A laboratory image acquisition systemwas used for capturing images of plantlets sawn in square agar plates.The image acquisition system consists of a digital reflex camera (CanonEOS 300D) attached to a 55 mm focal length lens (Canon EF-S series),mounted on a reproduction device (Kaiser RS), which included 4 lightunits (4×150 Watts light bulb) and located in a darkroom.

Digital imaging in Greenhouse—The image capturing process was repeatedevery 3-4 days starting at day 7 till day 30. The same camera attachedto a 24 mm focal length lens (Canon EF series), placed in a custom madeiron mount, was used for capturing images of larger plants sawn in whitetubs in an environmental controlled greenhouse. The white tubs weresquare shape with measurements of 36×26.2 cm and 7.5 cm deep. During thecapture process, the tubs were placed beneath the iron mount, whileavoiding direct sun light and casting of shadows. This process wasrepeated every 3-4 days for up to 30 days.

An image analysis system was used, which consists of a personal desktopcomputer (Intel P4 3.0 GHz processor) and a public domain program—ImageJ1.37, Java based image processing program, which was developed at theU.S. National Institutes of Health and is freely available on theinternet at Hypertext Transfer Protocol://rsbweb (dot) nih (dot) gov/.Images were captured in resolution of 6 Mega Pixels (3072×2048 pixels)and stored in a low compression JPEG (Joint Photographic Experts Groupstandard) format. Next, analyzed data was saved to text files andprocessed using the JMP statistical analysis software (SAS institute).

Leaf analysis—Using the digital analysis leaves data was calculated,including leaf number, area, perimeter, length and width. On day 30, 3-4representative plants were chosen from each plot of blocks A, B and C.The plants were dissected, each leaf was separated and was introducedbetween two glass trays, a photo of each plant was taken and the variousparameters (such as leaf total area, laminar length etc.) werecalculated from the images. The blade circularity was calculated aslaminar width divided by laminar length.

Root analysis—During 17 days, the different ecotypes were grown intransparent agar plates. The plates were photographed every 3 daysstarting at day 7 in the photography room and the roots development wasdocumented (see examples in FIGS. 3A-F). The growth rate of roots wascalculated according to Formula VII.Relative growth rate of root coverage=Regression coefficient of rootcoverage along time course.  Formula VII:

Vegetative growth rate analysis—was calculated according to FormulaVIII. The analysis was ended with the appearance of overlapping plants.Relative vegetative growth rate area=Regression coefficient ofvegetative area along time course.  Formula VIII

For comparison between ecotypes the calculated rate was normalized usingplant developmental stage as represented by the number of true leaves.In cases where plants with 8 leaves had been sampled twice (for exampleat day 10 and day 13), only the largest sample was chosen and added tothe Anova comparison.

Seeds in siliques analysis—On day 70, 15-17 siliques were collected fromeach plot in blocks D and E. The chosen siliques were light brown colorbut still intact. The siliques were opened in the photography room andthe seeds were scatter on a glass tray, a high resolution digitalpicture was taken for each plot. Using the images the number of seedsper silique was determined.

Seeds average weight—At the end of the experiment all seeds from plotsof blocks A-C were collected. An average weight of 0.02 grams wasmeasured from each sample, the seeds were scattered on a glass tray anda picture was taken. Using the digital analysis, the number of seeds ineach sample was calculated.

Oil percentage in seeds—At the end of the experiment all seeds fromplots of blocks A-C were collected. Columbia seeds from 3 plots weremixed grounded and then mounted onto the extraction chamber. 210 ml ofn-Hexane (Cat No. 080951 Biolab Ltd.) were used as the solvent. Theextraction was performed for 30 hours at medium heat 50° C. Once theextraction has ended the n-Hexane was evaporated using the evaporator at35° C. and vacuum conditions. The process was repeated twice. Theinformation gained from the Soxhlet extractor (Soxhlet, F. Diegewichtsanalytische Bestimmung des Milchfettes, Polytechnisches J.(Dingier's) 1879, 232, 461) was used to create a calibration curve forthe Low Resonance NMR. The content of oil of all seed samples wasdetermined using the Low Resonance NMR (MARAN Ultra-Oxford Instrument)and its MultiQuant sowftware package.

Silique length analysis—On day 50 from sowing, 30 siliques fromdifferent plants in each plot were sampled in block A. The chosensiliques were green-yellow in color and were collected from the bottomparts of a grown plant's stem. A digital photograph was taken todetermine silique's length.

Dry weight and seed yield—On day 80 from sowing, the plants from blocksA-C were harvested and left to dry at 30° C. in a drying chamber. Thebiomass and seed weight of each plot was separated, measured and dividedby the number of plants. Dry weight=total weight of the vegetativeportion above ground (excluding roots) after drying at 30° C. in adrying chamber; Seed yield per plant=total seed weight per plant (gr).

Oil yield—The oil yield was calculated using Formula IX.Seed Oil yield=Seed yield per plant (gr) * Oil % in seed  Formula IX:

Harvest Index (seed)—The harvest index was calculated using Formula IV(described above): Harvest Index=Average seed yield per plant/ Averagedry weight.

Experimental Results

Nine different Arabidopsis ecotypes were grown and characterized for 18parameters (named as vectors).

TABLE 10 Arabidopsis correlated parameters (vectors) Correlatedparameter with Correlation ID Root length day 13 (cm) 1 Root length day7 (cm) 2 Relative root growth (cm/day) day 13 3 Fresh weight per plant(gr) at bolting stage 4 Dry matter per plant (gr) 5 Vegetative growthrate (cm²/day) till 8 true leaves 6 Blade circularity 7 Lamina width(cm) 8 Lamina length (cm) 9 Total leaf area per plant (cm) 10 1000 Seedweight (gr) 11 Oil % per seed 12 Seeds per silique 13 Silique length(cm) 14 Seed yield per plant (gr) 15 Oil yield per plant (mg) 16 HarvestIndex 17 Leaf width/length 18 Table 10. Provided are the Arabidopsiscorrelated parameters (correlation ID Nos. 1-18). Abbreviations: Cm =centimeter(s); gr = gram(s); mg = milligram(s).

The characterized values are summarized in Tables 11 and 12 below.

TABLE 11 Measured parameters in Arabidopsis ecotypes Ecotype 15 16 12 115 17 10 13 14 An-1 0.34 118.63 34.42 0.0203 0.64 0.53 46.86 45.44 1.06Col-0 0.44 138.73 31.19 0.0230 1.27 0.35 109.89 53.47 1.26 Ct-1 0.59224.06 38.05 0.0252 1.05 0.56 58.36 58.47 1.31 Cvi 0.42 116.26 27.760.0344 1.28 0.33 56.80 35.27 1.47 (N8580) Gr-6 0.61 218.27 35.49 0.02021.69 0.37 114.66 48.56 1.24 Kondara 0.43 142.11 32.91 0.0263 1.34 0.32110.82 37.00 1.09 Ler-1 0.36 114.15 31.56 0.0205 0.81 0.45 88.49 39.381.18 Mt-0 0.62 190.06 30.79 0.0226 1.21 0.51 121.79 40.53 1.18 Shakdara0.55 187.62 34.02 0.0235 1.35 0.41 93.04 25.53 1.00 Table 11. Providedare the values of each of the parameters measured in Arabidopsisecotypes: 15 = Seed yield per plant (gram); 16 = oil yield per plant(mg); 12 = oil % per seed; 11 = 1000 seed weight (gr); 5 = dry matterper plant (gr); 17 = harvest index; 10 = total leaf area per plant (cm);13 = seeds per silique; 14 = Silique length (cm).

TABLE 12 Additional measured parameters in Arabidopsis ecotypes Ecotype6 3 2 1 4 9 8 18 7 An-1 0.313 0.631 0.937 4.419 1.510 2.767 1.385 0.3530.509 Col-0 0.378 0.664 1.759 8.530 3.607 3.544 1.697 0.288 0.481 Ct-10.484 1.176 0.701 5.621 1.935 3.274 1.460 0.316 0.450 Cvi 0.474 1.0890.728 4.834 2.082 3.785 1.374 0.258 0.370 (N8580) Gr-6 0.425 0.907 0.9915.957 3.556 3.690 1.828 0.356 0.501 Kondara 0.645 0.774 1.163 6.3724.338 4.597 1.650 0.273 0.376 Ler-1 0.430 0.606 1.284 5.649 3.467 3.8771.510 0.305 0.394 Mt-0 0.384 0.701 1.414 7.060 3.479 3.717 1.817 0.3350.491 Shakdara 0.471 0.782 1.251 7.041 3.710 4.149 1.668 0.307 0.409Table 12. Provided are the values of each of the parameters measured inArabidopsis ecotypes: 6 = Vegetative growth rate (cm²/day) until 8 trueleaves; 3 = relative root growth (cm/day) (day 13); 2 = Root length day7 (cm); 1 = Root length day 13 (cm); 4 = fresh weight per plant (gr) atbolting stage; 9 = Lamima length (cm); 8 = Lamina width (cm); 18 = Leafwidth/length; 7 = Blade circularity.

Table 13, below, provides selected genes of some embodiments of theinvention, the characterized parameters (which are used as x axis forcorrelation) and the correlated tissue transcriptom along with thecorrelation value (R, calculated using Pearson correlation). When thecorrelation coefficient (R) between the levels of a gene's expression ina certain tissue and a phenotypic performance across ecotypes is high inabsolute value (between 0.5-1), there is an association between the gene(specifically the expression level of this gene) and the phenotypiccharacter.

TABLE 13 Correlation between the expression level of selected genes inspecific tissues or developmental stages and the phenotypic performanceacross Arabidopsis ecotypes Gene Name Expression Set Correlation VectorR P LYM88 E 13 0.75035 0.03198 LYM89 D 10 0.88062 0.00886 LYM89 D 40.84712 0.01614 LYM89 A 6 0.84690 0.00797 LYM89 D 5 0.83715 0.01879LYM89 D 6 0.70174 0.07884 LYM152 E 14 0.85500 0.00682 Table 13. Providedare the correlations between the expression level of yield improvinggenes and their homologs in specific tissues or developmental stages(expression sets) and the phenotypic performance (correlation vector)across Arabidopsis ecotypes. The phenotypic characters [correlation(Corr.) vector (Vec.)] include yield (seed yield, oil yield, oilcontent), biomass, growth rate and/or vigor components as described inTables 10-12. Exp. Set = expression set according to Table 9hereinabove.

Example 5 Production of Arabidopsis Transcriptom and High ThroughputCorrelation Analysis of Normal and Nitrogen Limiting Conditions Using44K Arabidopsis Oligonucleotide Micro-Array

In order to produce a high throughput correlation analysis, the presentinventors utilized a Arabidopsis oligonucleotide micro-array, producedby Agilent Technologies [Hypertext Transfer Protocol://World Wide Web(dot) chem (dot) agilent (dot) com/Scripts/PDS (dot) asp?1Page=50879].The array oligonucleotide represents about 44,000 Arabidopsis genes andtranscripts. To define correlations between the levels of RNA expressionwith NUE, yield components or vigor related parameters various plantcharacteristics of 14 different Arabidopsis ecotypes were analyzed.Among them, ten ecotypes encompassing the observed variance wereselected for RNA expression analysis. The correlation between the RNAlevels and the characterized parameters was analyzed using Pearsoncorrelation test [Hypertext Transfer Protocol://World Wide Web (dot)davidmlane (dot) com/hyperstat/A34739 (dot) html].

Experimental Procedures

RNA extraction—Two tissues of plants [leaves and stems] growing at twodifferent nitrogen fertilization levels (1.5 mM Nitrogen or 6 mMNitrogen) were sampled and RNA was extracted as described in Examples 3above. For convenience, each micro-array expression information tissuetype has received a Set ID as summarized in Table14 below.

TABLE 14 Tissues used for Arabidopsis transcriptom expression setsExpression Set Set ID Leaves at 1.5 mM Nitrogen fertilization A Leavesat 6 mM Nitrogen fertilization B Stems at 1.5 mM Nitrogen fertilizationC Stem at 6 mM Nitrogen fertilization D Table 14: Provided are theidentification (ID) letters of each of the Arabidopsis expression sets.

Assessment of Arabidopsis yield components and vigor related parametersunder different nitrogen fertilization levels—10 Arabidopsis accessionsin 2 repetitive plots each containing 8 plants per plot were grown atgreenhouse. The growing protocol used was as follows: surface sterilizedseeds were sown in Eppendorf tubes containing 0.5×Murashige-Skoog basalsalt medium and grown at 23° C. under 12-hour light and 12-hour darkdaily cycles for 10 days. Then, seedlings of similar size were carefullytransferred to pots filled with a mix of perlite and peat in a 1:1ratio. Constant nitrogen limiting conditions were achieved by irrigatingthe plants with a solution containing 1.5 mM inorganic nitrogen in theform of KNO₃, supplemented with 2 mM CaCl₂, 1.25 mM KH₂PO₄, 1.50 mMMgSO₄, 5 mM KCl, 0.01 mM H₃BO₃ and microelements, while normalirrigation conditions (Normal Nitrogen conditions) was achieved byapplying a solution of 6 mM inorganic nitrogen also in the form of KNO₃,supplemented with 2 mM CaCl₂, 1.25 mM KH₂PO₄, 1.50 mM MgSO₄, 0.01 mMH₃BO₃ and microelements. To follow plant growth, trays were photographedthe day nitrogen limiting conditions were initiated and subsequentlyevery 3 days for about 15 additional days. Rosette plant area was thendetermined from the digital pictures. ImageJ software was used forquantifying the plant size from the digital pictures [Hypertext TransferProtocol://rsb (dot) info (dot) nih (dot) gov/ij] utilizing proprietaryscripts designed to analyze the size of rosette area from individualplants as a function of time. The image analysis system included apersonal desktop computer (Intel P4 3.0 GHz processor) and a publicdomain program—ImageJ 1.37 (Java based image processing program, whichwas developed at the U.S. National Institutes of Health and freelyavailable on the internet [Hypertext Transfer Protocol://rsbweb (dot)nih (dot) gov/]. Next, analyzed data was saved to text files andprocessed using the JMP statistical analysis software (SAS institute).

Data parameters collected are summarized in Table 15, hereinbelow.

TABLE 15 Arabidopsis correlated parameters (vectors) Correlatedparameter with Correlation Id N 1.5 mM; Rosette Area at day 8 [cm²] 1 N1.5 mM; Rosette Area at day 10 [cm²] 2 N 1.5 mM; Plot Coverage at day 8[%] 3 N 1.5 mM; Plot Coverage at day 10 [%] 4 N 1.5 mM; Leaf Number atday 10 5 N 1.5 mM; Leaf Blade Area at day 10 [cm²] 6 N 1.5 mM; RGR ofRosette Area at day 3 [cm²/day] 7 N 1.5 mM; t50 Flowering [day] 8 N 1.5mM; Dry Weight [gr/plant] 9 N 1.5 mM; Seed Yield [gr/plant] 10 N 1.5 mM;Harvest Index 11 N 1.5 mM; 1000 Seeds weight [gr] 12 N 1.5 mM; seedyield/rosette area at day 10 [gr/cm²] 13 N 1.5 mM; seed yield/leaf blade[gr/cm²] 14 N 1.5 mM; % Seed yield reduction compared to N 6 mM 15 N 1.5mM; % Biomass reduction compared to N 6 mM 16 N 1.5 mM; N level/DW [SPADunit/gr] 17 N 1.5 mM; DW/N level [gr/SPAD unit] 18 N 1.5 mM; seedyield/N level [gr/SPAD unit] 19 N 6 mM; Rosette Area at day 8 [cm²] 20 N6 mM; Rosette Area at day 10 [cm²] 21 N 6 mM; Plot Coverage at day 8 [%]22 N 6 mM; Plot Coverage at day 10 [%] 23 N 6 mM; Leaf Number at day 1024 N 6 mM; Leaf Blade Area at day 10 25 N 6 mM; RGR of Rosette Area atday 3 [cm²/gr] 26 N 6 mM; t50 Flowering [day] 27 N 6 mM; Dry Weight[gr/plant] 28 N 6 mM; Seed Yield [gr/plant] 29 N 6 mM; Harvest Index 30N 6 mM; 1000 Seeds weight [gr] 31 N 6 mM; seed yield/rosette area day atday 10 [gr/cm²] 32 N 6 mM; seed yield/leaf blade [gr/cm²] 33 N 6 mM; Nlevel/FW 34 N 6 mM; DW/N level [gr/SPAD unit] 35 N 6 mM; N level/DW(SPAD unit/gr plant) 36 N 6 mM; Seed yield/N unit [gr/SPAD unit] 37Table 15. Provided are the Arabidopsis correlated parameters (vectors).“N” = Nitrogen at the noted concentrations; “gr.” = grams; “SPAD” =chlorophyll levels; “t50” = time where 50% of plants flowered; “gr/SPADunit” = plant biomass expressed in grams per unit of nitrogen in plantmeasured by SPAD. “DW” = Plant Dry Weight; “FW” = Plant Fresh weight; “Nlevel/DW” = plant Nitrogen level measured in SPAD unit per plant biomass[gr]; “DW/N level” = plant biomass per plant [gr]/SPAD unit; RosetteArea (measured using digital analysis); Plot Coverage at the indicatedday [%] (calculated by the dividing the total plant area with the totalplot area); Leaf Blade Area at the indicated day [cm²] (measured usingdigital analysis); RGR (relative growth rate) of Rosette Area at theindicated day [cm²/day]; t50 Flowering [day] (the day in which 50% ofplant flower); seed yield/rosette area at day 10 [gr/cm²] (calculated);seed yield/leaf blade [gr/cm²] (calculated); seed yield/N level [gr/SPADunit] (calculated).

Assessment of NUE, yield components and vigor-related parameters—TenArabidopsis ecotypes were grown in trays, each containing 8 plants perplot, in a greenhouse with controlled temperature conditions for about12 weeks. Plants were irrigated with different nitrogen concentration asdescribed above depending on the treatment applied. During this time,data was collected documented and analyzed. Most of chosen parameterswere analyzed by digital imaging.

Digital Imaging—Greenhouse Assay

An image acquisition system, which consists of a digital reflex camera(Canon EOS 400D) attached with a 55 mm focal length lens (Canon EF-Sseries) placed in a custom made Aluminum mount, was used for capturingimages of plants planted in containers within an environmentalcontrolled greenhouse. The image capturing process is repeated every 2-3days starting at day 9-12 till day 16-19 (respectively) fromtransplanting.

An image processing system was used, which consists of a personaldesktop computer (Intel P4 3.0 GHz processor) and a public domainprogram—ImageJ 1.37, Java based image processing software, which wasdeveloped at the U.S. National Institutes of Health and is freelyavailable on the internet at Hypertext Transfer Protocol://rsbweb (dot)nih (dot) gov/. Images were captured in resolution of 10 Mega Pixels(3888×2592 pixels) and stored in a low compression JPEG (JointPhotographic Experts Group standard) format. Next, image processingoutput data was saved to text files and analyzed using the JMPstatistical analysis software (SAS institute).

Leaf analysis—Using the digital analysis leaves data was calculated,including leaf number, leaf blade area, plot coverage, Rosette diameterand Rosette area.

Relative growth rate area: The relative growth rate of the rosette andthe leaves was calculated according to Formulas XIV and XVII,respectively.

Seed yield and 1000 seeds weight—At the end of the experiment all seedsfrom all plots were collected and weighed in order to measure seed yieldper plant in terms of total seed weight per plant (gr). For thecalculation of 1000 seed weight, an average weight of 0.02 grams wasmeasured from each sample, the seeds were scattered on a glass tray anda picture was taken. Using the digital analysis, the number of seeds ineach sample was calculated.

Dry weight and seed yield—At the end of the experiment, plant wereharvested and left to dry at 30° C. in a drying chamber. The biomass wasseparated from the seeds, weighed and divided by the number of plants.Dry weight=total weight of the vegetative portion above ground(excluding roots) after drying at 30° C. in a drying chamber.

Harvest Index (seed)—The harvest index was calculated using Formula IVas described above [Harvest Index=Average seed yield per plant/ Averagedry weight].

T₅₀ days to flowering—Each of the repeats was monitored for floweringdate. Days of flowering was calculated from sowing date till 50% of theplots flowered.

Plant nitrogen level—The chlorophyll content of leaves is a goodindicator of the nitrogen plant status since the degree of leafgreenness is highly correlated to this parameter. Chlorophyll contentwas determined using a Minolta SPAD 502 chlorophyll meter andmeasurement was performed at time of flowering. SPAD meter readings weredone on young fully developed leaf. Three measurements per leaf weretaken per plot. Based on this measurement, parameters such as the ratiobetween seed yield per nitrogen unit [seed yield/N level=seed yield perplant [gr]/SPAD unit], plant DW per nitrogen unit [DW/ N level=plantbiomass per plant [g]/SPAD unit], and nitrogen level per gram of biomass[N level/DW=SPAD unit/ plant biomass per plant (gr)] were calculated.

Percent of seed yield reduction—measures the amount of seeds obtained inplants when grown under nitrogen-limiting conditions compared to seedyield produced at normal nitrogen levels expressed in %.

Experimental Results

10 different Arabidopsis accessions (ecotypes) were grown andcharacterized for 37 parameters as described above. The average for eachof the measured parameters was calculated using the JMP software.Subsequent correlation analysis between the various transcriptom sets(Table 14) was conducted. Following are the results integrated to thedatabase.

TABLE 16 Correlation between the expression level of selected genes ofthe invention and their homologs in tissues under limiting or normalnitrogen fertilization and the phenotypic performance across Arabidopsisecotypes Correlation Gene Name Expression Set Vector R P LYM88 C 170.93533 0.01955 LYM88 D 16 0.79502 0.01044 LYM8_H1 D 31 0.7452820.021184 LYM10_H7 C 24 0.895562 0.000458 LYM10_H7 C 5 0.77817 0.008026LYM10_H7 C 21 0.725922 0.017459 LYM10_H7 C 2 0.717752 0.019423 LYM10_H8C 8 0.850748 0.001806 LYM10_H8 C 27 0.7752 0.008432 LYM10_H8 C 150.77175 0.008921 LYM10_H9 A 1 0.844351 0.002119 LYM10_H9 A 2 0.7557230.01146 LYM10_H9 A 20 0.733447 0.015776 LYM10_H9 A 21 0.722114 0.018356LYM14_H2 B 27 0.892136 0.000519 LYM14_H2 B 8 0.830273 0.002942 LYM14_H2C 8 0.816286 0.003967 LYM14_H2 C 8 0.794197 0.006071 LYM14_H2 C 270.767463 0.009557 LYM14_H2 C 27 0.733255 0.015818 LYM14_H2 D 1 0.7251160.027066 LYM14_H3 B 15 0.855842 0.001582 LYM14_H3 C 8 0.802977 0.005158LYM14_H3 B 8 0.79811 0.005651 LYM14_H3 B 12 0.792747 0.006233 LYM14_H3 B27 0.785721 0.007057 LYM14_H3 C 27 0.734206 0.015613 LYM14_H3 A 90.720081 0.018848 LYM137_H11 C 20 0.815207 0.004055 LYM137_H11 C 210.79814 0.005648 LYM137_H11 D 5 0.754601 0.018779 LYM137_H11 C 240.701843 0.023676 LYM152_H1 D 5 0.714383 0.030592 LYM152_H1 D 5 0.7134420.030914 LYM236_H4 B 27 0.937557 6.17E−05 LYM236_H4 B 8 0.9212470.000153 LYM236_H4 B 15 0.865782 0.001204 LYM236_H4 B 28 0.7095950.02153 LYM236_H5 A 10 0.737484 0.014922 LYM236_H5 B 10 0.71158 0.021004Table 16. Provided are the correlations (R) between the expressionlevels of yield improving genes and their homologs in tissues (leaves orstems) under limiting (1.5 mM Nitrogen) or normal (6 mM Nitrogen)conditions (Expression sets) and the phenotypic performance in variousyield (seed yield, oil yield, oil content), biomass, growth rate and/orvigor components [Correlation (Corr.) vector (Vec.)] under limiting ornormal Nitrogen conditions. Corr. Vec. = correlation vector according toTable 15 hereinabove; Exp. Set = expression set according to Table 14hereinabove.

Example 6 Production of Sorghum Transcriptom and High ThroughputCorrelation Analysis with ABST Related Parametrers Using 44K SorghumOligonucleotide Micro-Arrays

In order to produce a high throughput correlation analysis, the presentinventors utilized a Sorghum oligonucleotide micro-array, produced byAgilent Technologies [Hypertext Transfer Protocol://World Wide Web (dot)chem. (dot) agilent (dot) com/Scripts/PDS (dot) asp?1Page=50879]. Thearray oligonucleotide represents about 44,000 Sorghum genes andtranscripts. In order to define correlations between the levels of RNAexpression with ABST and yield components or vigor related parameters,various plant characteristics of 17 different sorghum varieties wereanalyzed. Among them, 10 varieties encompassing the observed variancewere selected for RNA expression analysis. The correlation between theRNA levels and the characterized parameters was analyzed using Pearsoncorrelation test [Hypertext Transfer Protocol://World Wide Web (dot)davidmlane (dot) com/hyperstat/A34739 (dot) html].

Correlation of Sorghum Varieties Across Ecotype Grown Under SevereDrought Conditions

Experimental Procedures

17 Sorghum varieties were grown in 3 repetitive plots, in field.Briefly, the growing protocol was as follows: sorghum seeds were sown insoil and grown under normal condition until around 35 days from sowing,around V8 (Last leaf visible, but still rolled up, ear beginning toswell). At this point, irrigation was stopped, and severe drought stresswas developed. In order to define correlations between the levels of RNAexpression with drought, yield components or vigor related parameters,the 17 different sorghum varieties were analyzed. Among them, 10varieties encompassing the observed variance were selected for RNAexpression analysis. The correlation between the RNA levels and thecharacterized parameters was analyzed using Pearson correlation test[Hypertext Transfer Protocol://World Wide Web (dot) davidmlane (dot)com/hyperstat/A34739 (dot) html].

RNA extraction—All 10 selected Sorghum varieties were sample per eachtreatment. Plant tissues [Flag leaf, Flower meristem and Flower] growingunder severe drought stress and plants grown under Normal conditionswere sampled and RNA was extracted as described in Examples 3 above. Forconvenience, each micro-array expression information tissue type hasreceived a Set ID as summarized in Table 17 below.

TABLE 17 Sorghum transcriptom expression sets Expression Set Set IDSorghum field/Normal/flower meristem 1 Sorghum field/Normal/flower 2Sorghum field/Normal/flag leaf 3 Drought Stress: Flag leaf 4 Table 17:Provided are the sorghum transcriptom expression sets 1, 2, 3 and 4.Flag leaf = the leaf below the flower; Flower meristem = Apical meristemfollowing panicle initiation; Flower = the flower at the anthesis day.Expression sets 1, 2 and 3 are from plants grown under normalconditions. Expression set 4 derived from plants grown under droughtconditions.

The following parameters were collected using digital imaging system:

Average Grain Area (cm²)—At the end of the growing period the grainswere separated from the Plant ‘Head’. A sample of ˜200 grains wereweight, photographed and images were processed using the below describedimage processing system. The grain area was measured from those imagesand was divided by the number of grains.

Average Grain Length (cm)—At the end of the growing period the grainswere separated from the Plant ‘Head’. A sample of ˜200 grains wereweight, photographed and images were processed using the below describedimage processing system. The sum of grain lengths (longest axis) wasmeasured from those images and was divided by the number of grains.

Head Average Area (cm²) At the end of the growing period 5 ‘Heads’ were,photographed and images were processed using the below described imageprocessing system. The ‘Head’ area was measured from those images andwas divided by the number of ‘Heads’.

Head Average Length (cm) At the end of the growing period 5 ‘Heads’were, photographed and images were processed using the below describedimage processing system. The ‘Head’ length (longest axis) was measuredfrom those images and was divided by the number of ‘Heads’.

The image processing system was used, which consists of a personaldesktop computer (Intel P4 3.0 GHz processor) and a public domainprogram—ImageJ 1.37, Java based image processing software, which wasdeveloped at the U.S. National Institutes of Health and is freelyavailable on the internet at Hypertext Transfer Protocol://rsbweb (dot)nih (dot) gov/. Images were captured in resolution of 10 Mega Pixels(3888×2592 pixels) and stored in a low compression JPEG (JointPhotographic Experts Group standard) format. Next, image processingoutput data for seed area and seed length was saved to text files andanalyzed using the JMP statistical analysis software (SAS institute).

Additional parameters were collected either by sampling 5 plants perplot or by measuring the parameter across all the plants within theplot.

Total Seed Weight/Head (gr.)—At the end of the experiment (plant‘Heads’) heads from plots within blocks A-C were collected. 5 heads wereseparately threshed and grains were weighted, all additional heads werethreshed together and weighted as well. The average grain weight perhead was calculated by dividing the total grain weight by number oftotal heads per plot (based on plot). In case of 5 heads, the totalgrains weight of 5 heads was divided by 5.

FW Head/Plant gr—At the end of the experiment (when heads wereharvested) total and 5 selected heads per plots within blocks A-C werecollected separately. The heads (total and 5) were weighted (gr.)separately and the average fresh weight per plant was calculated fortotal (FW Head/Plant gr based on plot) and for 5 (FW Head/Plant gr basedon 5 plants).

Plant height—Plants were characterized for height during growing periodat 5 time points. In each measure, plants were measured for their heightusing a measuring tape. Height was measured from ground level to top ofthe longest leaf.

Plant leaf number—Plants were characterized for leaf number duringgrowing period at 5 time points. In each measure, plants were measuredfor their leaf number by counting all the leaves of 3 selected plantsper plot.

Relative Growth Rate was calculated using Formulas X and XI.Relative growth rate of plant height=Regression coefficient of plantheight along time course.  Formula XRelative growth rate of plant leaf number=Regression coefficient ofplant leaf number along time course.  Formula XI

SPAD—Chlorophyll content was determined using a Minolta SPAD 502chlorophyll meter and measurement was performed 64 days post sowing.SPAD meter readings were done on young fully developed leaf. Threemeasurements per leaf were taken per plot.

Vegetative dry weight and Heads—At the end of the experiment (whenInflorescence were dry) all Inflorescence and vegetative material fromplots within blocks A-C were collected. The biomass and Heads weight ofeach plot was separated, measured and divided by the number of Heads.

Dry weight=total weight of the vegetative portion above ground(excluding roots) after drying at 70° C. in oven for 48 hours;

Harvest Index (HI) (Sorghum)—The harvest index was calculated usingFormula XII.Harvest Index=Average grain dry weight per Head/(Average vegetative dryweight per Head+Average Head dry weight)  Formula XII:

FW Heads/(FW Heads+FW Plants)—The total fresh weight of heads and theirrespective plant biomass were measured at the harvest day. The headsweight was divided by the sum of weights of heads and plants.

Experimental Results

16 different sorghum varieties were grown and characterized fordifferent parameters: The average for each of the measured parameter wascalculated using the JMP software (Tables 19-20) and a subsequentcorrelation analysis between the various transcriptom sets (Table 17)and the average parameters, was conducted (Tables 21). Results were thenintegrated to the database.

TABLE 18 Sorghum correlated parameters (vectors) Correlation VectorCorrelation Id Average Seed Area cm2-normal A Average Seed Lengthcm-normal B FW/Plant gr based on plot-normal C FW Head/Plant gr based on5 plants-normal D FW Head/Plant gr based on plot-normal E FW Heads/(FWHeads + FW Plants) F based on plot-normal Head Average Area cm2-normal GHead Average Length cm-normal H HI-normal J Leaf SPAD 64 Days PostSowing-normal K Relative Growth Rate of Leaf Num-normal L RelativeGrowth Rate of Plant Height-normal M Total Seed Weight/Head gr based onplot-normal N Total Seed Weight/Head gr based on 5 heads-normal O Table18. Provided are the Sorghum correlated parameters (vectors). “gr.” =grams; “SPAD” = chlorophyll levels; “FW” = Plant Fresh weight; “normal”= standard growth conditions.

TABLE 19 Measured parameters in Sorghum accessions Seed Id A B C D E F GH J 20 0.1047 0.3856 162.6 406.5 175.2 0.51 120.1 25.58 200.7 21 0.11240.4017 212.6 518 223.5 0.5101 167.6 26.84 127 22 0.1313 0.4446 334.8 14856.4 0.1154 85.14 21.02 51.8 24 0.1293 0.4496 313.5 423 111.6 0.2626157.3 26.84 122.4 25 0.1204 54.53 26 0.177 93.92 27 0.1098 0.3999 151.1423.5 126.2 0.4591 168.5 31.33 327.3 28 0.1134 0.4054 137.6 386.5 107.70.4316 109.3 23.18 231.5 29 0.1022 0.3837 168 409.5 123.9 0.4249 135.125.7 241.4 30 0.118 0.4186 129 328.9 102.8 0.4416 169 28.82 304.1 310.1205 0.4302 97.62 391 82.33 0.4581 156.1 28.13 335.6 32 0.1106 0.400399.32 435.8 77.59 0.4473 112.1 22.97 349.6 33 0.1165 0.4094 112.2 429.591.17 0.4474 154.7 28.09 293.2 34 0.108 0.4008 157.4 441 150.4 0.5134171.7 30 410.9 35 0.1048 0.3947 130.5 415.8 109.1 0.4595 168.5 30.54285.1 36 0.1097 0.3953 135.7 429.5 107.6 0.4425 162.5 27.17 282.7 370.1053 0.3924 209.2 428.5 130.9 0.3856 170.5 29.26 204 Table 19:Provided are the values of each of the parameters (as described above)measured in Sorghum accessions (Seed ID) under normal and droughtconditions. Growth conditions are specified in the experimentalprocedure section.

TABLE 20 Additional measured parameters in Sorghum accessions Seed Id LM N O 20 0.1032 1.891 31.12 47.4 21 1.622 26.35 46.3 22 0.2128 3.41818.72 28.37 24 0.1862 2.425 38.38 70.4 25 0.1898 3.118 26 0.1599 3.32327 0.1957 2.178 47.67 63.45 28 0.1694 2.188 31 44.45 29 0.1821 2.57239.99 56.65 30 2.046 38.36 60 31 2.069 32.1 45.45 32 0.1754 2.547 32.6958.19 33 0.117 2.327 32.79 70.6 34 0.207 3.039 51.53 70.1 35 0.18592.335 35.71 53.95 36 0.151 2.516 38.31 59.87 37 0.24 2.81 42.44 52.65Table 20: Provided are the values of each of the parameters (asdescribed above) measured in Sorghum accessions (Seed ID) under normaland drought conditions. Growth conditions are specified in theexperimental procedure section.

TABLE 21 Correlation between the expression level of selected genes ofsome embodiments of the invention in various tissues and the phenotypicperformance under normal or abiotic stress conditions across Sorghumaccessions Gene Name Cluster Name Exp. Set Corr. Vec. R P LYM174sorghum|gb161.crp|AW284303 1 J 0.746 0.013251 LYM263sorghum|gb161.crp|AI622410 2 O 0.860 0.00292 LYM263sorghum|gb161.crp|AI622410 2 J 0.847 0.00196 LYM5 H21sorghum|09v1|SB04G031180 1 B 0.898 0.00101 LYM5 H21sorghum|09v1|SB04G031180 1 A 0.896 0.00107 LYM8 H23sorghum|09v1|SB01G000490 1 O 0.755 0.018718 LYM8 H23sorghum|09v1|SB01G000490 2 O 0.714 0.030884 LYM10 H272sorghum|09v1|SB04G005280 3 L 0.756 0.029952 LYM14 H44sorghum|09v1|SB02G044050 2 E 0.769 0.015504 LYM24 H10sorghum|09v1|SB03G044280 2 C 0.774 0.014343 LYM24 H10sorghum|09v1|SB03G044280 3 B 0.743 0.021898 LYM24 H10sorghum|09v1|SB03G044280 3 A 0.728 0.026226 LYM35 H7sorghum|09v1|SB06G031730 2 E 0.823 0.006385 LYM73 H8sorghum|09v1|SB07G004300 1 E 0.748 0.02039 LYM82 H16sorghum|09v1|SB10G002420 3 J 0.783 0.007439 LYM82 H16sorghum|09v1|SB10G002420 3 N 0.780 0.013111 LYM82 H16sorghum|09v1|SB10G002420 3 O 0.726 0.02673 LYM82 H16sorghum|09v1|SB10G002420 3 G 0.723 0.027818 LYM111 H10sorghum|09v1|SB03G036350 3 C 0.892 0.00122 LYM111 H10sorghum|09v1|SB03G036350 3 A 0.753 0.019062 LYM111 H10sorghum|09v1|SB03G036350 3 B 0.702 0.035192 LYM119 H1sorghum|09v1|SB05G003680 2 C 0.759 0.017691 LYM131 H19sorghum|09v1|SB06G027970 1 E 0.841 0.004488 LYM131 H19sorghum|09v1|SB06G027970 3 B 0.787 0.011775 LYM131 H19sorghum|09v1|SB06G027970 3 A 0.762 0.017013 LYM131 H19sorghum|09v1|SB06G027970 1 F 0.700 0.024184 LYM131 H20sorghum|09v1|SB07G006320 1 E 0.854 0.003353 LYM137 H285sorghum|09v1|SB06G021660 2 F 0.747 0.013056 LYM137 H285sorghum|09v1|SB06G021660 1 E 0.716 0.030132 LYM137 H286sorghum|09v1|SB10G005240 1 E 0.786 0.012037 LYM140 H27sorghum|09v1|SB06G028990 1 C 0.772 0.014832 LYM148 H14sorghum|09v1|SB10G026570 1 B 0.812 0.007885 LYM148 H14sorghum|09v1|SB10G026570 1 A 0.770 0.015311 LYM148 H14sorghum|09v1|SB10G026570 1 C 0.768 0.015705 LYM162 H7sorghum|09v1|SB03G043995 1 N 0.837 0.004911 LYM215 H2sorghum|09v1|SB03G043980 1 N 0.718 0.029262 LYM178 H13sorghum|09v1|SB03G008890 3 B 0.862 0.002833 LYM178 H13sorghum|09v1|SB03G008890 3 A 0.792 0.010892 LYM178 H14sorghum|09v1|SB07G001060 2 A 0.768 0.01572 LYM179 H0sorghum|09v1|SB08G006470 1 O 0.818 0.006992 LYM109 H2sorghum|09v1|SB05G003660 1 B 0.762 0.017077 LYM109 H2sorghum|09v1|SB05G003660 3 A 0.751 0.019579 LYM109 H2sorghum|09v1|SB05G003660 1 A 0.732 0.025074 LYM112 H2sorghum|09v1|SB02G039985 1 B 0.827 0.005944 LYM112 H2sorghum|09v1|SB02G039985 3 B 0.790 0.011246 LYM112 H2sorghum|09v1|SB02G039985 1 A 0.789 0.011426 LYM112 H2sorghum|09v1|SB02G039985 3 A 0.701 0.035452 LYM123 H7sorghum|09v1|SB06G031680 1 B 0.769 0.015524 LYM181 H6sorghum|09v1|SB02G034110 1 B 0.740 0.022556 LYM181 H6sorghum|09v1|SB02G034110 3 N 0.724 0.027264 LYM181 H6sorghum|09v1|SB02G034110 3 O 0.702 0.035114 LYM182 H12sorghum|09v1|SB06G015280 1 E 0.767 0.015834 LYM206 H2sorghum|09v1|SB07G021090 3 N 0.795 0.010488 LYM188 H13sorghum|09v1|SB01G007950 1 E 0.788 0.011658 LYM198 H1sorghum|09v1|SB01G045460 1 E 0.829 0.005689 LYM201 H37sorghum|09v1|SB04G022350 2 N 0.741 0.022246 LYM201 H37sorghum|09v1|SB04G022350 2 D 0.709 0.032326 LYM201 H37sorghum|09v1|SB04G022350 2 H 0.701 0.035468 LYM207 H3sorghum|09v1|SB06G023870 3 K 0.781 0.007669 LYM207 H3sorghum|09v1|SB06G023870 1 E 0.768 0.015595 LYM207 H3sorghum|09v1|SB06G023870 3 O 0.718 0.029344 LYM207 H3sorghum|09v1|SB06G023870 1 N 0.716 0.02988 LYM208 H8sorghum|09v1|SB01G032070 1 N 0.734 0.024302 LYM208 H8sorghum|09v1|SB01G032070 1 E 0.701 0.03525 LYM212 H9sorghum|09v1|SB01G045480 1 E 0.841 0.004537 LYM221 H3sorghum|09v1|SB01G034610 2 A 0.728 0.02604 LYM221 H3sorghum|09v1|SB01G034610 2 C 0.721 0.028264 LYM224 H3sorghum|09v1|SB02G040000 3 C 0.835 0.005096 LYM224 H3sorghum|09v1|SB02G040000 3 L 0.827 0.011397 LYM224 H3sorghum|09v1|SB02G040000 3 M 0.708 0.021888 LYM232 H3sorghum|09v1|SB02G000450 1 O 0.808 0.00839 LYM232 H3sorghum|09v1|SB02G000450 1 N 0.759 0.017814 LYM236 H139sorghum|09v1|SB09G029110 1 A 0.859 0.00303 LYM236 H139sorghum|09v1|SB09G029110 1 B 0.836 0.004971 LYM248 H5sorghum|09v1|SB04G000645 3 L 0.878 0.004118 LYM248 H5sorghum|09v1|SB04G000645 1 N 0.868 0.002424 LYM183 H11sorghum|09v1|SB01G003070 1 E 0.832 0.005437 LYM183 H11sorghum|09v1|SB01G003070 1 N 0.749 0.020124 LYM267 H1sorghum|09v1|SB01G044240 2 A 0.797 0.010102 LYM267 H1sorghum|09v1|SB01G044240 2 B 0.753 0.019206 LYM267 H1sorghum|09v1|SB01G044240 1 H 0.707 0.033248 LYM267 H1sorghum|09v1|SB01G044240 1 O 0.705 0.033872 LYM267 H1sorghum|09v1|SB01G044240 1 N 0.705 0.033976 LYM270 H0sorghum|09v1|SB02G040045 1 E 0.820 0.006742 LYM271 H10sorghum|09v1|SB02G040020 1 N 0.780 0.013152 LYM273 H6sorghum|09v1|SB03G044410 3 B 0.955 5.91E−05 LYM273 H6sorghum|09v1|SB03G044410 3 A 0.950  8.6E−05 LYM284 H24sorghum|09v1|SB03G027960 1 E 0.867 0.00247 LYM289 H52sorghum|09v1|SB09G005410 3 O 0.928 0.000307 LYM289 H52sorghum|09v1|SB09G005410 3 N 0.830 0.005588 LYM289 H52sorghum|09v1|SB09G005410 3 H 0.781 0.012924 LYM289 H52sorghum|09v1|SB09G005410 3 G 0.714 0.03066 LYM289 H52sorghum|09v1|SB09G005410 3 D 0.704 0.03412 LYM290 H13sorghum|09v1|SB01G009390 1 E 0.766 0.01617 Table 21. Provided are thecorrelations (R) between the expression levels of yield improving genesand their homologs in tissues (Flag leaf, Flower meristem and Flower;Expression (Exp.) sets) and the phenotypic performance in various yield,biomass, growth rate and/or vigor components [Correlation (Corr.) vector(Vec.)] under stress conditions or normal conditions across Sorghumaccessions.

Sorghum vigor related parameters under 100 mM NaCl and low temperature(10±2° C.)—Ten Sorghum varieties were grown in 3 repetitive plots, eachcontaining 17 plants, at a net house under semi-hydroponics conditions.Briefly, the growing protocol was as follows: Sorghum seeds were sown intrays filled with a mix of vermiculite and peat in a 1:1 ratio.Following germination, the trays were transferred to the high salinitysolution (100 mM NaCl in addition to the Full Hogland solution), lowtemperature (10±2° C. in the presence of Full Hogland solution) or atNormal growth solution [Full Hogland solution at 28±2° C].

Full Hogland solution consists of: KNO₃—0.808 grams/liter, MgSO₄—0.12grams/liter, KH₂PO₄—0.172 grams/liter and 0.01% (volume/volume) of‘Super coratin’ micro elements (Iron-EDDHA[ethylenediamine-N,N′-bis(2-hydroxyphenylacetic acid)]—40.5 grams/liter;Mn—20.2 grams/liter; Zn 10.1 grams/liter; Co 1.5 grams/liter; and Mo 1.1grams/liter), solution's pH should be 6.5-6.8].

RNA extraction—All 10 selected Sorghum varieties were sampled per eachtreatment. Two tissues [leaves and roots] growing at 100 mM NaCl, lowtemperature (10±2° C.) or under Normal conditions (full Hogland at atemperature between 28±2° C.) were sampled and RNA was extracted asdescribed in Example 3 above.

TABLE 22 Sorghum transcriptom expression sets Expression Set Set IDSorghum roots under cold 1 Sorghum vegetative meristem NaCl 2 Sorghumvegetative meristem under low nitrogen 3 Sorghum vegetative meristemunder cold conditions 4 Sorghum roots under NaCl 5 Sorghum vegetativemeristem under normal conditions 6 Sorghum roots under low nitrogen 7Sorghum roots under normal 8 Table 22: Provided are the Sorghumtranscriptom expression sets. Cold conditions = 10 ± 2° C.; NaCl = 100mM NaCl; low nitrogen = 1.2 mM Nitrogen; Normal conditions = 16 mMNitrogen.

Experimental Results

10 different Sorghum varieties were grown and characterized for thefollowing parameters: “Leaf number Normal”=leaf number per plant undernormal conditions (average of five plants); “Plant Height Normal”=plantheight under normal conditions (average of five plants); “Root DW 100 mMNaCl”—root dry weight per plant under salinity conditions (average offive plants); The average for each of the measured parameter wascalculated using the JMP software and values are summarized in Table 24below. Subsequent correlation analysis between the various transcriptomsets and the average parameters were conducted (Table 25). Results werethen integrated to the database.

TABLE 23 Sorghum correlated parameters (vectors) Correlation VectorCorr. Id DW Root/Plant - Cold A DW Root/Plant - 100 mM NaCl B DWShoot/Plant - Low Nitrogen C DW Root/Plant - Low Nitrogen D Leaf numberTP-3* - Cold E Leaf number TP-3* - 100 mM NaCl F Plant Height TP-3* -100 mM NaCl G DW Shoot/Plant - Cold H DW Shoot/Plant - Normal I PlantHeight TP-3* - Low Nitrogen J Leaf number TP-3* - Low Nitrogen K DWShoot/Plant - 100 mM NaCl L Leaf number TP-3* - Normal M Table 23:Provided are the Sorghum correlated parameters. Cold conditions = 10 ±2° C.; NaCl = 100 mM NaCl; low nitrogen = 1.2 mM Nitrogen; Normalconditions = 16 mM Nitrogen *TP-3 refers to time point 3.

TABLE 24 Sorghum accessions, measured parameters Seed ID F B L G E A H MI 20 3.67 0.35 0.66 14.63 3.88 0.83 1.03 4.17 0.81 22 3.88 1.45 2.4316.31 4.16 0.95 1.34 4.48 1.89 26 4.28 1.49 2.40 20.56 4.52 1.47 1.714.93 2.51 27 4.03 0.81 1.61 14.70 4.28 1.06 1.28 4.53 1.26 28 3.97 1.031.77 16.43 4.33 0.71 1.12 4.52 1.55 29 3.98 0.95 1.66 16.12 4.17 1.381.69 4.64 1.50 30 3.90 2.00 2.23 15.61 3.94 2.04 2.24 4.49 1.93 31 4.181.39 2.76 18.71 4.26 1.03 1.26 4.79 1.95 34 3.70 1.29 1.29 13.65 4.201.01 1.08 4.37 1.48 37 3.82 1.76 1.55 15.72 4.04 1.01 1.02 4.54 1.85Table 24: Provided are the measured parameters under 100 mM NaCl and lowtemperature (8-10° C.) conditions of Sorghum accessions (Seed ID)according to the Correlation ID numbers (described in Table 23 above) asfollows: F [100 mM NaCl: leaf Number]; B [100 mM NaCl: Root DW]; L [100mM NaCl: Shoot DW]; G [100 mM NaCl: Plant height]; E [low temperature:leaf Number]; A [low temperature: Root DW]; H [low temperature: ShootDW];; M [Normal: leaf Number]; I [Normal: Shoot DW].

TABLE 25 Correlation between the expression level of selected genes ofsome embodiments of the invention in roots and the phenotypicperformance under normal or abiotic stress conditions across Sorghumaccessions Gene Name Cluster Id Exp. Set Corr. Vec. R P LYM263sorghum|gb161.crp|AI622410 5 G 0.705635 0.183016 LYM263sorghum|gb161.crp|AI622410 5 F 0.908761 0.032626 LYM263sorghum|gb161.crp|AI622410 8 I 0.836212 0.004969 LYM2 H8sorghum|09v1|SB07G004285 1 A 0.73969 0.01447 LYM4 H11sorghum|09v1|SB03G000920 2 B 0.83675 0.00491 LYM4 H11sorghum|09v1|SB03G000920 2 B 0.73187 0.02499 LYM4 H11sorghum|09v1|SB03G000920 4 E 0.70634 0.03342 LYM14 H43sorghum|09v1|SB01G038730 1 A 0.71433 0.02029 LYM19 H12sorghum|09v1|SB05G009990 5 F 0.97628 0.00437 LYM19 H12sorghum|09v1|SB05G009990 5 G 0.88580 0.04552 LYM24 H10sorghum|09v1|SB03G044280 4 H 0.75256 0.01929 LYM24 H10sorghum|09v1|SB03G044280 4 H 0.74948 0.02008 LYM73 H8sorghum|09v1|SB07G004300 5 F 0.97233 0.00550 LYM73 H8sorghum|09v1|SB07G004300 5 F 0.92449 0.02462 LYM73 H8sorghum|09v1|SB07G004300 4 E 0.73646 0.02364 LYM83 H12sorghum|09v1|SB09G026370 2 F 0.70736 0.03305 LYM129 H4sorghum|09v1|SB03G044510 1 E 0.72429 0.01784 LYM129 H4sorghum|09v1|SB03G044510 2 F 0.72339 0.02761 LYM129 H4sorghum|09v1|SB03G044510 6 I 0.71891 0.02907 LYM129 H4sorghum|09v1|SB03G044510 6 I 0.71123 0.03168 LYM129 H4sorghum|09v1|SB03G044510 2 F 0.70792 0.03285 LYM140 H27sorghum|09v1|SB06G028990 2 G 0.80589 0.00873 LYM140 H27sorghum|09v1|SB06G028990 2 F 0.78965 0.01136 LYM140 H27sorghum|09v1|SB06G028990 6 I 0.71625 0.02996 LYM153 H9sorghum|09v1|SB10G003440 4 H 0.78966 0.01136 LYM153 H9sorghum|09v1|SB10G003440 4 H 0.73143 0.02512 LYM153 H9sorghum|09v1|SB10G003440 4 A 0.71026 0.03202 LYM115 H0sorghum|09v1|SB01G043900 2 F 0.74903 0.02019 LYM188 H13sorghum|09v1|SB01G007950 5 F 0.87882 0.04971 LYM203 H14sorghum|09v1|SB04G005460 2 B 0.78001 0.01316 LYM217 H3sorghum|09v1|SB01G043910 5 B 0.94269 0.01633 LYM217 H3sorghum|09v1|SB01G043910 5 B 0.93691 0.01884 LYM228 H1sorghum|09v1|SB09G006910 1 A 0.72334 0.01806 LYM232 H3sorghum|09v1|SB02G000450 2 L 0.77653 0.01385 LYM232 H3sorghum|09v1|SB02G000450 2 F 0.72326 0.02766 LYM240 H12sorghum|09v1|SB02G038240 4 H 0.76382 0.01659 LYM240 H12sorghum|09v1|SB02G038240 2 L 0.73895 0.02293 LYM251 H106sorghum|09v1|SB01G006180 5 F 0.95275 0.01224 LYM284 H24sorghum|09v1|SB03G027960 6 M 0.76300 0.01677 LYM289 H53sorghum|09v1|SB10G002980 5 G 0.91500 0.02936 Table 25. Provided are thecorrelations (R) between the expression levels yield improving genes andtheir homologs in various tissues [Expression (Exp.) sets] and thephenotypic performance [yield, biomass, growth rate and/or vigorcomponents (Correlation vector)] under abiotic stress conditions(salinity) or normal conditions across sorghum accessions. Corr. Vec. =correlation vector as described hereinabove (Table 23).

Example 7 Gene Cloning and Generation of Binary Vectors for PlantExpression

To validate their role in improving oil content, plant yield, seedyield, biomass, fiber yield and/or quality, growth rate, ABST, NUEand/or vigor, selected genes were over-expressed in plants, as follows.

Cloning Strategy

Genes listed in Examples 1-6 hereinabove were cloned into binary vectorsfor the generation of transgenic plants. For cloning, the full-lengthopen reading frame (ORF) was first identified. In case of ORF-ESTclusters and in some cases already published mRNA sequences wereanalyzed to identify the entire open reading frame by comparing theresults of several translation algorithms to known proteins from otherplant species. To clone the full-length cDNAs, reverse transcription(RT) followed by polymerase chain reaction (PCR; RT-PCR) was performedon total RNA extracted from leaves, flowers, siliques or other planttissues, growing under normal conditions. Total RNA was extracted asdescribed in Example 3 above. Production of cDNA and PCR amplificationwas performed using standard protocols described elsewhere (Sambrook J.,E. F. Fritsch, and T. Maniatis. 1989. Molecular Cloning. A LaboratoryManual., 2nd Ed. Cold Spring Harbor Laboratory Press, New York.) whichare well known to those skilled in the art. PCR products were purifiedusing PCR purification kit (Qiagen). In case where the entire codingsequence was not found, RACE kit from Invitrogen (RACE=R apid A ccess tocDNA E nds) was used to access the full cDNA transcript of the gene fromthe RNA samples described above.

In case genomic DNA was cloned, as in the case of LYM122 (SEQ IDNO:3739) and LYM273 (SEQ ID NO:3738), the genes were amplified by directPCR on genomic DNA extracted from leaf tissue using the DNAeasy kit(Qiagen Cat. No. 69104).

Usually, 2 sets of primers were synthesized for the amplification ofeach gene from a cDNA or a genomic sequence; an external set of primersand an internal set (nested PCR primers). When needed (e.g., when thefirst PCR reaction did not result in a satisfactory product forsequencing), an additional primer (or two) of the nested PCR primerswere used. Table 26 below provides primers used for cloning of selectedgenes.

TABLE 26 The PCR primers used for cloning the genes of some embodimentsof the invention into high copy vectors Restriction Enzymes Gene Nameused for cloning Primers used for amplification LYM1 SalI, XbaILYM1_NF_SalI (SEQ ID NO: 3740) AAAGTCGACAGTAGGCAATCATGTGTGAGGLYM1_NR_XbaI (SEQ ID NO: 3741) AATTCTAGACTAAGCTAGAGAGCTCGACTAATGC LYM10XhoI, KpnI LYM10 NF XhoI (SEQ ID NO: 3742) ATACTCGAGTCTCCAACCTTGCGAAGGLYM10 EF XhoI (SEQ ID NO: 3743) ATACTCGAGAACCCGATCTCTCCAACC LYM10 NRKpnI (SEQ ID NO: 3744) TATGGTACCCCTGCGAATTCTTGCCTTAG LYM10 ER KpnI (SEQID NO: 3745) TATGGTACCTGACGCCACCCTCAACTC LYM100 SalI, XbaILYM100_NF_SalI (SEQ ID NO: 3746) AAAGTCGACAGGAAACCCTAACGAAGATACCLYM100_EF_SalI (SEQ ID NO: 3747) AAAGTCGACGGAAACATACAGGTCGATTGAGLYM100_NR_XbaI (SEQ ID NO: 3748) AAATCTAGAGGGAAAGTTTAGTAGCACCAACLYM100_ER_XbaI (SEQ ID NO: 3749) AAATCTAGAATATAACGTTAGAGCGGAGTGG LYM102BamHI, XhoI LYM102_NF_BamHI (SEQ ID NO: 3750)AAAGGATCCGAGCTGCTGATTGTGAGTCAAG LYM102_NR_XhoI (SEQ ID NO: 3751)AAACTCGAGCTAGGACAGCACTTCAGATAAGACC LYM103 BamHI, XhoI LYM103_NF_BamHI(SEQ ID NO: 3752) AAAGGATCCCGACCGAGTCAATCAATCC LYM103_NR_XhoI (SEQ IDNO: 3753) AAACTCGAGAACAAGTATGACAGGCCAACTC LYM105 BamHI, XhoILYM105_NF_BamHI (SEQ ID NO: 3754) AAAGGATCCTAGCTAGCTTACTCCACAGTGCLYM105_EF_BamHI (SEQ ID NO: 3755) AAAGGATCCAGCCACACGCTTAGCTTAGCLYM105_NR_XhoI (SEQ ID NO: 3756) AAACTCGAGCGAGCAGAAATTAACAGCTAACLYM105_ER_XhoI (SEQ ID NO: 3757) AAACTCGAGACTACAGATCCAAAGCACGAAC LYM106SalI, XbaI LYM106_NF_SalI (SEQ ID NO: 3758)AAAGTCGACACTCAACGTAGTTCCTCACCTG LYM106_NR_XbaI (SEQ ID NO: 3759)AAATCTAGAAAGCTTTAGTTCTAGCACACGAC LYM107 BamHI, XhoI LYM107_NF_BamHI (SEQID NO: 3760) AAAGGATCCGTACTCCTATATTAGGCTCGCTC LYM107_EF_BamHI (SEQ IDNO: 3761) AAAGGATCCCTGCGTACTCCTATATTAGGCTC LYM107_NR_XhoI (SEQ ID NO:3762) AAACTCGAGAATTTGGTATCAGAAACCTTGC LYM107_ER_XhoI (SEQ ID NO: 3763)AATCTCGAGTGAATCACTCAGTGTGCATGAC LYM109 XhoI, StuI LYM109_F2_XhoI (SEQ IDNO: 3764) AAACTCGAGCCCAGCGGACTCCTACTCTG LYM109_F2_XhoI (SEQ ID NO: 3764)AAACTCGAGCCCAGCGGACTCCTACTCTG LYM109_R2_StuI (SEQ ID NO: 3765)TTTAGGCCTTCACAGTCTTACAAGTCCGATTGCC LYM109_R2_StuI (SEQ ID NO: 3765)TTTAGGCCTTCACAGTCTTACAAGTCCGATTGCC LYM110 BamHI, XhoI LYM110_NF_BamHI(SEQ ID NO: 3766) AAAGGATCCGAACCAAACCTCGGAGAAAC LYM110_NR_XhoI (SEQ IDNO: 3767) AAACTCGAGACCATCACCTGTAATACAACTACC LYM111 XhoI, SacILYM111_NF_XhoI (SEQ ID NO: 3768) AAACTCGAGGAATCTGGTTGCTCATCTCATCLYM111_EF_XhoI (SEQ ID NO: 3769) AAACTCGAGCTTCACAACGGACGAGAGGLYM111_NR_SacI (SEQ ID NO: 3770) AAAGAGCTCATAATCGTTGGAACTTGGAATCLYM111_ER_SacI (SEQ ID NO: 3771) AAAGAGCTCACAGCTTATCCCTACATGCTTC LYM112BamHI, XhoI LYM112_NF_BamHI (SEQ ID NO: 3772)AAAGGATCCTCAATTGAATCAGATGCTCCAC LYM112_EF_BamHI (SEQ ID NO: 3773)AAAGGATCCATTCCTTTGACCGATTTCTTG LYM112_NR_XhoI (SEQ ID NO: 3774)AAACTCGAGCTAATTAAGACAAATCAGTGGCACC LYM112_ER_XhoI (SEQ ID NO: 3775)AAACTCGAGACAGAAGGTCGATGTTGATCTG LYM113 SalI, XbaI LYM113_NF_SalI (SEQ IDNO: 3776) AAAGTCGACTTCTTGATCTAAATTTGGGTGG LYM113_EF_SalI (SEQ ID NO:3777) AAAGTCGACACTAGCTCTGCACTTTCCCTG LYM113_NR_XbaI (SEQ ID NO: 3778)AAATCTAGAGATTCAAGTGCGTTGTCTGTC LYM113_ER_XbaI (SEQ ID NO: 3779)AAATCTAGACTTGGTATTTACAGGACAATCG LYM115 BamHI, XhoI LYM115_F_BamHI (SEQID NO: 3780) AAAGGATCCTCGCCGCAGATGGAAGTCT LYM115_ER_XhoI (SEQ ID NO:3781) TTTCTCGAGCAAACTCGTCTGGAGATGGG LYM116 SalI, XbaI LYM116_EF_SalI(SEQ ID NO: 3782) AAAGTCGACTTGGCTCCGGATATCGCA LYM116_ER_XbaI (SEQ ID NO:3783) AAATCTAGAAGGCAGATGTTCATAACCACAC LYM117 LYM117_F2_BamHI (SEQ ID NO:3784) AAAGGATCCCGTCGTCAAGTGCTGGC LYM117_R2_EcoRV (SEQ ID NO: 3785)AGTGATATCTCAATGTTTAGGGTCTCGGCATG LYM119 SalI, XbaI LYM119_NF_SalI (SEQID NO: 3786) AAAGTCGACATCGAGTTGTTCGTCCGTC LYM119_NR_XbaI (SEQ ID NO:3787) AAATCTAGAACACCAAGCGTACATCTCAGAC LYM12 XhoI, KpnI LYM12 EF XhoI(SEQ ID NO: 3788) TTACTCGAGTGCTTCTCTTCTTTCCTCTCTG LYM12 ER KpnI (SEQ IDNO: 3789) ATAGGTACCTCACAGCAAACTAACATGAACCG LYM120 BamHI, XhoILYM120_NF_BamHI (SEQ ID NO: 3790) AAAGGATCCGGAAGTCCGGAGTTGGAAGLYM120_NR_XhoI (SEQ ID NO: 3791) AAACTCGAGCAGTCACTCACACGCTACTACG LYM121BamHI, XhoI LYM121_NF_BamHI (SEQ ID NO: 3792)AAAGGATCCACTGCTGACCAACTTCAGTGTC LYM121_EF_BamHI (SEQ ID NO: 3793)AAAGGATCCGACAAGGCTATCACATCCAATC LYM121_NR_XhoI (SEQ ID NO: 3794)AAACTCGAGTTCTAAAGAAACAATCACGCAC LYM121_ER_XhoI (SEQ ID NO: 3795)AAACTCGAGAGCAGAAGAAACTAGGCATGTG LYM122_G LYM122_EF_BamHI (SEQ ID NO:3796) AAAGGATCCTGCAGCCCTGACACACAAC LYM122_ER_XhoI (SEQ ID NO: 3797)AAACTCGAGACCATCATGTAATACCCACCTC LYM125 LYM125_EF_BamHI (SEQ ID NO: 3798)AAAGGATCCCTGTGCTTGGAGTAGACACGAG LYM125_ER_KpnI (SEQ ID NO: 3799)AAAGGTACCGGAGAATTTGGATCAGTGCAG LYM127 LYM127_F2_BamHI (SEQ ID NO: 3800)TTTGGATCCCTTCTTGCTGTCGAACACCAG LYM127_R2_XhoI (SEQ ID NO: 3801)TTTCTCGAGGTCATGGGATTCTTGTCAGATACTAG LYM128 BamHI, XhoI LYM128_NF_BamHI(SEQ ID NO: 3802) TTTGGATCCTTCACACCTCACCGAGCG LYM128_EF_BamHI (SEQ IDNO: 3803) AAAGGATCCAACCCGTTCACACCTCACC LYM128_NR_XhoI (SEQ ID NO: 3804)AAACTCGAGGATCACTTGACAATTACCGTGC LYM128_ER_XhoI (SEQ ID NO: 3805)AAACTCGAGTATGCTGATATGCCAGGTTTAC LYM129 SalI, XbaI LYM129_NF_SalI (SEQ IDNO: 3806) AAAGTCGACATTCAGTCTTGTCGGCTACATC LYM129_EF_SalI (SEQ ID NO:3807) AAAGTCGACTAGATCAGCCTCGATTCATCTC LYM129_NR_XbaI (SEQ ID NO: 3808)AAATCTAGAGCTTAATCAGAAGAAACGAACC LYM129_ER_XbaI (SEQ ID NO: 3809)AAATCTAGAAATTGCACAATACATGAACACG LYM13 SalI, BamHI LYM13_NF_SalI (SEQ IDNO: 3810) AAAGTCGACCAAGCGGTAGGAGATGAGG LYM13_NR_BamHI (SEQ ID NO: 3811)AAAGGATCCTTATAACAACTATTCCCGGTAAGC LYM130 SalI, XbaI LYM130_NF_SalI (SEQID NO: 3812) AAAGTCGACAGAAATTAAGTTGCCGGAGAG LYM130_NR_XbaI (SEQ ID NO:3813) AAATCTAGAATGCAGATGAGAGCTCAAGATG LYM131 SalI, XhoI LYM131_NF_SalI(SEQ ID NO: 3814) AAAGTCGACTCCCTACCCTAGTCGATCTCC LYM131_EF_SalI (SEQ IDNO: 3815) AAAGTCGACGACTCGTCTCCTCGTTGCTC LYM131_NF_SalI (SEQ ID NO: 3814)AAAGTCGACTCCCTACCCTAGTCGATCTCC LYM131_ER_XhoI (SEQ ID NO: 3816)AAACTCGAGTATAACACAGGCATAAAGCAGC LYM132 BamHI, XhoI LYM132_EF_BamHI (SEQID NO: 3817) AAAGGATCCATATTGGAATGCTTCTGTCGTC LYM132_ER_XhoI (SEQ ID NO:3818) AAACTCGAGTACACGATAATCACAAACCACG LYM134 BamHI, XhoI LYM134_NF_BamHI(SEQ ID NO: 3819) AAAGGATCCATGGTGATTCGGTTGTTGTTAG LYM134_EF_BamHI (SEQID NO: 3820) AAAGGATCCATCGTTGAATTGATGGTGATTC LYM134_NR_XhoI (SEQ ID NO:3821) AAACTCGAGTCATACGTCGAAGAACCAGAAC LYM134_ER_XhoI (SEQ ID NO: 3822)AAACTCGAGTGAAACTTTCGCCAACTACAC LYM135 LYM135_NF_SalI (SEQ ID NO: 3823)AAAGTCGACTTCTGATCTGCTCAGCTAAAGG LYM135_NR_SacI (SEQ ID NO: 3824)AAAGAGCTCCTGATGCACAAATATGGTAACG LYM136 BamHI, KpnI LYM136_NF_BamHI (SEQID NO: 3825) AAAGGATCCCCGGTTCTATGTGTAGGAAGAG LYM136_EF_BamHI (SEQ ID NO:3826) AAAGGATCCCAGGATGAGTGTTGATCCATTC LYM136_NR_KpnI (SEQ ID NO: 3827)AAAGGTACCGTCACAAACGCCTCAACATATC LYM136_ER_KpnI (SEQ ID NO: 3828)AAAGGTACCTTCACCATATTGCTACGAAATC LYM137 SalI, XbaI LYM137_NF_SalI (SEQ IDNO: 3829) AAAGTCGACAGTTCAAGAGGCTGTCCTGAG LYM137_NR_XbaI (SEQ ID NO:3830) AAATCTAGATCCAATAACATAAGAAACCACG LYM138 SalI, SacI LYM138_EF_SalI(SEQ ID NO: 3831) AAAGTCGACAACGAACCACTCTTCTGCATC LYM138_ER_SacI (SEQ IDNO: 3832) AAAGAGCTCGAAGCAACCTGGAAATAAACTC LYM14 EcoRV, PstILYM14_NF_EcoRV (SEQ ID NO: 3833) AAAGATATCCTCCTCAGATCCACCACCACLYM14_NR_PstI (SEQ ID NO: 3834) AATCTGCAGCTAAAATATTCAGGGCTTGTTG LYM140XhoI, SacI LYM140_F_XhoI (SEQ ID NO: 3835) AAACTCGAGCTCCAGCACACGGACGAGLYM140_ER_SacI (SEQ ID NO: 3836) AAAGAGCTCTACGAGTACGAATTATTGCCAG LYM141LYM141_NF_BamHI (SEQ ID NO: 3837) AAAGGATCCACAAGCGTCTTCTTCGTCTTCLYM141_NR_KpnI (SEQ ID NO: 3838) AAAGGTACCCCATGCCACCCTTACTATACTC LYM142SalI, SacI LYM142_NF_SalB (SEQ ID NO: 3839)TAAGTCGACCACACAGAGCACAGCACAGAG LYM142_NR_SacB (SEQ ID NO: 3840)TGAGCTCTGAACATGCGACCGTATGC LYM143 SalI, XbaI LYM143_NF_SalI (SEQ ID NO:3841) AAAGTCGACCACTAGCGCACAGATCTCCTAC LYM143_NR_XbaI (SEQ ID NO: 3842)AAATCTAGAAATAGTGTCCATGAGACGAACG LYM144 SalI, EcoRV LYM144_NF_SalI (SEQID NO: 3843) AAAGTCGACACGACGAGGAGGAGGATG LYM144_NR_EcoRV (SEQ ID NO:3844) AATGATATCACGCATGGATTTCTTTAAGTTG LYM145 BamHI, XhoI LYM145_F2_BamHI(SEQ ID NO: 3845) ATCGGATCCTAGCTTTGCCCAGTTTTGCT LYM145_F2_BamHI (SEQ IDNO: 3845) ATCGGATCCTAGCTTTGCCCAGTTTTGCT LYM145_R2_XhoI (SEQ ID NO: 3846)TTTCTCGAGCTATGCAGTTTTAGCCTAAGGCAAG LYM145_R2_XhoI (SEQ ID NO: 3846)TTTCTCGAGCTATGCAGTTTTAGCCTAAGGCAAG LYM146 LYM146_F2_KpnI (SEQ ID NO:3847) AAAGGTACCCGAGGTCGTCACGCACAG LYM146_R2_KpnI (SEQ ID NO: 3848)AATGGTACCTGGGTGGTTAGACAGCAAGG LYM147 SalI, XbaI LYM147_NF_SalI (SEQ IDNO: 3849) AAAGTCGACCTCTGGCGCTCTCCTATACTC LYM147_EF_SalI (SEQ ID NO:3850) AAAGTCGACAGTACGTGTACGTTTCAGGGAG LYM147_NR_XbaI (SEQ ID NO: 3851)AAATCTAGAAGTACCACTAGCAGAAAGGCAG LYM147_ER_XbaI (SEQ ID NO: 3852)AAATCTAGATGGCACCCAATACTAGTACCAC LYM148 BamHI, XhoI LYM148_NF_BamHI (SEQID NO: 3853) AAAGGATCCCTTACCCTTCCCTGAGATCC LYM148_NR_XhoI (SEQ ID NO:3854) AAACTCGAGCTAACTACCAAAGTTCAAGCAGCTC LYM149 SalI, XbaILYM149_NF_SalI (SEQ ID NO: 3855) AAAGTCGACACCATGAGTTCATAACAAGAAGGLYM149_NR_XbaI (SEQ ID NO: 3856) AAATCTAGACTAATACATGGAAGTGCAGACATGCLYM15 SalI, XbaI LYM15_NF_SalI (SEQ ID NO: 3857)AAAGTCGACAGGTACAGTATAGTATGACACCGAC LYM15_NR_XbaI (SEQ ID NO: 3858)AATTCTAGACTACTGTTAACCGCTGATTATATCC LYM152 SalI, XbaI LYM152_NF_SalI (SEQID NO: 3859) TTTGTCGACGAAGAAGAGATGGGAGTTTTCTC LYM152_NR_XbaI (SEQ ID NO:3860) AAATCTAGAATTTCTGACATTACATTATAGTCTCG LYM153 SalI, XbaILYM153_NF_SalI (SEQ ID NO: 3861) AAAGTCGACTTCTCCTCCTACGTTCTACTGGLYM153_NR_XbaI (SEQ ID NO: 3862) AAATCTAGACTAACAGGGTTTCTCCACTAAGTAAGLYM155 SalI, XbaI LYM155_NF_SalI (SEQ ID NO: 3863)AAAGTCGACTCCACTATAAGCAACGCACC LYM155_EF_SalI (SEQ ID NO: 3864)AAAGTCGACGAAGGAAACTCGGTGACACG LYM155_NR_XbaI (SEQ ID NO: 3865)AAATCTAGAATGCCATGCTACTAAGAACCTAC LYM155_ER_XbaI (SEQ ID NO: 3866)AAATCTAGATAAACATCTCATGCCATGCTAC LYM156 StuI, StuI LYM156_NF_StuI (SEQ IDNO: 3867) TTTAGGCCTCAAGATCCGCAGAGATGATC LYM156 NR StuI_2 (SEQ ID NO:3868) AAAAGGCCTTTAAGTGCTTGCGTCGTTTTACAG LYM157_G XbaI, SacILYM157_EF_Xba_B (SEQ ID NO: 3869) AATCTAGACCTCGAGCCACCCACTTTCLYM157_ER_Sac_B (SEQ ID NO: 3870) TGAGCTCTCACCTTCATCTTGTCTTCACTGGTLYM159 SalI, XbaI LYM159_NF_SalI (SEQ ID NO: 3871)AAAGTCGACCTCTACCTTCTTCTTCGGTCAG LYM159_NR_XbaI (SEQ ID NO: 3872)AAATCTAGAAGCTTAGCTAGGCCAACAATAC LYM16 SalI, XbaI LYM16 NF SalI (SEQ IDNO: 3873) CTAGTCGACAAGAAATTGGCACAGAAATGG LYM16 NR XbaI (SEQ ID NO: 3874)TATTCTAGATCAAAGAGCCTAGTGAGCGTCTTC LYM160 SalI, XbaI LYM160_F2_SalI (SEQID NO: 3875) AAAGTCGACAGGCCAGACCAAAACCATG LYM160_F2_SalI (SEQ ID NO:3875) AAAGTCGACAGGCCAGACCAAAACCATG LYM160_NR_XbaI (SEQ ID NO: 3876)AAATCTAGAAGAGTAACATGGACACACGACC LYM160_R2_XbaI (SEQ ID NO: 3877)AATTCTAGATCAGTACAAGAGCCAGATGTCTGA LYM161 BamHI, XhoI LYM161_EF_BamHI(SEQ ID NO: 3878) AAAGGATCCGAGAGAGGAGCAAAGATTCACC LYM161_ER_XhoI (SEQ IDNO: 3879) AAACTCGAGTACAGGATGGTTGGTCTTCTTC LYM162 BamHI, XhoILYM162_NF_BamHI (SEQ ID NO: 3880) TTTGGATCCGCATCTAAGCCGAATTGAAGLYM162_NR_XhoI (SEQ ID NO: 3881) AAACTCGAGCTATTTCATGCTCAGTACCTGCACLYM164 SalI, XbaI LYM164_NF_SalI (SEQ ID NO: 3882)AAAGTCGACATCCAGATGCTTCACATTCTTG LYM164_NR_XbaI (SEQ ID NO: 3883)AAATCTAGATCGAGTTTGACACGAACTTATG LYM165 LYM165_F2_XhoI (SEQ ID NO: 3884)AAACTCGAGCTACTCCGATCGGATCCTGAC LYM165_R2_SacI (SEQ ID NO: 3885)AAAGAGCTCAAACGACGCACGGTCTCAC LYM17 SmaI, KpnI LYM17 NF X/SmaI (SEQ IDNO: 3886) ATACCCGGGTCTCTCAAGATGGTGGTGCTG LYM17 NR KpnI (SEQ ID NO: 3887)TATGGTACCAAGGGCTTAGCAAATTCTTTC LYM170 SalI, XbaI LYM170_NF_SalI (SEQ IDNO: 3888) AAAGTCGACATTCTTCGACCTCCTAAACTCC LYM170_EF_SalI (SEQ ID NO:3889) AAAGTCGACAGTCTCACACAGATCGCTTCAC LYM170_NR_XbaI (SEQ ID NO: 3890)AAATCTAGACTACCAACTCAGAACCAGGATGAG LYM170_ER_XbaI (SEQ ID NO: 3891)AAATCTAGACATACCTATAAGGCTATAACACTGC LYM172 BamHI, XhoI LYM172_NF_BamHI(SEQ ID NO: 3892) AAAGGATCCCTCGTCTTCGTCTACTCCACC LYM172_EF_BamHI (SEQ IDNO: 3893) AAAGGATCCCCTCACTCGTAGTCTCGTCTTC LYM172_NR_XhoI (SEQ ID NO:3894) AAACTCGAGGGAGCTTTGGAGAATAACAAAC LYM172_ER_XhoI (SEQ ID NO: 3895)AAACTCGAGCAACAGGTAACTCATTTCCACC LYM173 BamHI, XhoI LYM173_NF_BamHI (SEQID NO: 3896) AAAGGATCCTCATCAGTTCCCTGTTCTTCAG LYM173_NR_XhoI (SEQ ID NO:3897) AAACTCGAGATGACTGGACTAAAGCAACCAC LYM174 BamHI, KpnI LYM174_NF_BamHI(SEQ ID NO: 3898) AAAGGATCCCTCTTGCTAGGAGTAGCCTGC LYM174_NR_KpnI (SEQ IDNO: 3899) AAAGGTACCTATTATCCTACATGCCACATGC LYM175 SalI, XbaILYM175_NF_SalI (SEQ ID NO: 3900) AAAGTCGACCACTCCCTCTTATAGCCCACCLYM175_NR_XbaI (SEQ ID NO: 3901) AAATCTAGACTAAGTGTACAGTTCACGGCACG LYM176SalI, XbaI LYM176_NF_SalI (SEQ ID NO: 3902)AAAGTCGACTCTCGTTTCTCCTACCCTACAG LYM176_NR_XbaI (SEQ ID NO: 3903)AAATCTAGACTAACAGTTTCCAGTCAAAGCTACAG LYM178 SalI, XbaI LYM178_NF_SalI(SEQ ID NO: 3904) AAAGTCGACCTATCCATCCGCCACAAGAC LYM178_NR_XbaI (SEQ IDNO: 3905) AAATCTAGAACACAAGACACCATTTCTGGAG LYM179 SalI, XhoILYM179_NF_SalI (SEQ ID NO: 3906) AAAGTCGACAGGATTTCTCTAGGATAGCAGCLYM179_EF_SalI (SEQ ID NO: 3907) AAAGTCGACCTCAGTCGAGCGAGGATTTCLYM179_NR_XhoI (SEQ ID NO: 3908) AAACTCGAGAAACAGAGCCTAACAGACATGGLYM179_ER_XhoI (SEQ ID NO: 3909) AAACTCGAGGGGATGTTTAGACTGCTACAGG LYM180BamHI, XhoI LYM180_NF_BamHI (SEQ ID NO: 3910)TATGGATCCCGACCTTTGATACCAAGCAAG LYM180_NR_XhoI (SEQ ID NO: 3911)TTACTCGAGCACGGATTAGTTTGTAGTAGCATGG LYM181 LYM181_F2_BamHI (SEQ ID NO:3912) AATGGATCCTAAAAATGGCGGCTGCTACTC LYM181_R2_EcoRV (SEQ ID NO: 3913)TTTGATATCTCATACACGGTTTCATATGGTCGG LYM183 LYM183_EF_SalI (SEQ ID NO:3914) AAAGTCGACATCAAACCAACGAGAGCACTAC LYM183_ER_XbaI (SEQ ID NO: 3915)AAATCTAGAACTTCAGTGTACTTTCCCTTGC LYM184 LYM184_NF_BamHI (SEQ ID NO: 3916)AAAGGATCCAACACGACTTGTGAGTGAGAGC LYM184_EF_BamHI (SEQ ID NO: 3917)AAAGGATCCATATGAGTAACGCCATCAGGAG LYM184_NR_XhoI (SEQ ID NO: 3918)AAACTCGAGTGCCTCATTTAATCTTGGGTC LYM184_ER_XhoI (SEQ ID NO: 3919)AAACTCGAGGAAATTGCCTCATTTAATCTTG LYM185 BamHI, KpnI LYM185_NF_BamHI (SEQID NO: 3920) AAAGGATCCAATTCGAGATATTTGGCTGTTC LYM185_EF_BamHI (SEQ ID NO:3921) AAAGGATCCAGATAGCAAGATAGTCCGGTTG LYM185_NR_KpnI (SEQ ID NO: 3922)AAAGGTACCGGTCTATCACAAGCATCCTCAC LYM185_ER_KpnI (SEQ ID NO: 3923)AAAGGTACCACCACCTTTGTGATTGTTTCTC LYM186 SalI, XbaI LYM186_NF_SalI (SEQ IDNO: 3924) AAAGTCGACCGACCCAAATTGACATAACTC LYM186_NR_XbaI (SEQ ID NO:3925) AAATCTAGAATAGCTGGAACCTGGTATTGAC LYM188 BamHI, XhoI LYM188_EF_BamHI(SEQ ID NO: 3926) AAAGGATCCCGAGCTAGGGTTAGGGTTTC LYM188_ER_XhoI (SEQ IDNO: 3927) AAACTCGAGCAACAACTCACGCTACACATTC LYM189 SalI, XbaILYM189_NF_SalI (SEQ ID NO: 3928) AAAGTCGACCCACGTCCTAGAATGAAAGAGLYM189_EF_SalI (SEQ ID NO: 3929) AAAGTCGACTTCCTCTGCTTCCCACAGCLYM189_NR_XbaI (SEQ ID NO: 3930) AAATCTAGACTGTTCATTCACGGTTGCACLYM189_ER_XbaI (SEQ ID NO: 3931) AAATCTAGAGCAAATCTGTCGCTTTATTAGG LYM19SalI, XbaI LYM19_NF_SalI (SEQ ID NO: 3932)AAAGTCGACGAGAGAAGAGAGATGGTCCTCC LYM19_NR_XbaI (SEQ ID NO: 3933)AAATCTAGATTATCATGCTGACTTCTTGCCAC LYM192 XhoI, EcoRV LYM192_EF_XhoI (SEQID NO: 3934) AAACTCGAGTGAGCAGCGAGCCCTAAC LYM192_R_EcoRV (SEQ ID NO:3935) TTTGATATCTCACACTACTAGGGAGTGGAGTAGTAA CTTGA LYM193 BamHI, XhoILYM193_NF_BamHI (SEQ ID NO: 3936) AAAGGATCCCTAGTAGTGTTCTTCCCATTCGLYM193_EF_BamHI (SEQ ID NO: 3937) AAAGGATCCAACAATCCGTCCTTTCATTTGLYM193_NR_XhoI (SEQ ID NO: 3938) AAACTCGAGTAAACGACAGCGGTACACATACLYM193_ER_XhoI (SEQ ID NO: 3939) AAACTCGAGTACATCTCTAGGCAGCAAACAG LYM196LYM196_NF_BamHI (SEQ ID NO: 3940) AAAGGATCCGAGGACACCGCTTGCTTTCLYM196_NR_XhoI (SEQ ID NO: 3941) AAACTCGAGAACCTTGGATATGACCAATCAG LYM197BamHI, XhoI LYM197_EF_BamHI (SEQ ID NO: 3942)AAAGGATCCCTGTTGCCACATCTAGTGGTTC LYM197_ER_XhoI (SEQ ID NO: 3943)AAACTCGAGCACAATTCAGCGATTATTTCAG LYM198 BamHI, XhoI LYM198_F2_BamHI (SEQID NO: 3944) ATTGGATCCTTCATTTCCGCCATCCGT LYM198_R2_XhoI (SEQ ID NO:3945) AAACTCGAGCACCATCTCTTGCAGAAGGC LYM2 EcoRV, KpnI LYM2_NF_EcoRV (SEQID NO: 3946) AAAGATATCCGGTAGGTAGATGAAATTAAGG LYM2_NR_KpnI (SEQ ID NO:3947) CGAGGTACCCTAATATGCAGGTCAGCACACAAG LYM20 EcoRV, KpnI LYM20 NF EcoRV(SEQ ID NO: 3948) ATAGATATCACTCCGAATCCGACGCAC LYM20 EF EcoRV (SEQ ID NO:3949) ATAGATATCGAGATCCCAACTCCGAATCC LYM20 NR KpnI (SEQ ID NO: 3950)TATGGTACCCTACGTAAATCTCAGCACATGC LYM20 ER KpnI (SEQ ID NO: 3951)TATGGTACCCTTCTGCAACGTTATTTGAGG LYM200 BamHI, XhoI LYM200_NF_BamHI (SEQID NO: 3952) AAAGGATCCACTTTACCGGGCTACCATTC LYM200_EF_BamHI (SEQ ID NO:3953) AAAGGATCCTTACAAGAGCCTGTGAGCTGAG LYM200_NR_XhoI (SEQ ID NO: 3954)AAACTCGAGCTTATCTGGACCACACTTGGAC LYM200_ER_XhoI (SEQ ID NO: 3955)AAACTCGAGAAGAAATACATAGCCCTCCTCC LYM201 BamHI, XhoI LYM201_NF_BamHI (SEQID NO: 3956) AAAGGATCCGCCTCATCTCGGTTTACTATAAG LYM201_NR_XhoI (SEQ ID NO:3957) AAACTCGAGAAGTAGACACAAACCATCCTGG LYM203 BamHI, XhoI LYM203_EF_BamHI(SEQ ID NO: 3958) AAAGGATCCTCTATCAAATCAGCCACCTGTC LYM203_ER_XhoI (SEQ IDNO: 3959) AAACTCGAGCTAGCAACTTTGTAGACCAGACGTG LYM204 LYM204_NF_BamHI (SEQID NO: 3960) AAAGGATCCCTACTACCAGACAGAGAGGACAGG LYM204_EF_BamHI (SEQ IDNO: 3961) TTTGGATCCGCTTTCTGGCATCGCTACTAC LYM204_NR_XhoI (SEQ ID NO:3962) TGTCTCGAGTCAGTAGGAGTTTATGAGATGAACC LYM204_ER_Xho (SEQ ID NO: 3963)AAACTCGAGTCAACTCATCATCCGGAACATGGTAC LYM206 XhoI, EcoRV LYM206_EF_XhoI(SEQ ID NO: 3964) AAACTCGAGAATTCTAGCAAGGCAGCTCAG LYM206_ER_EcoRV (SEQ IDNO: 4199) AAAGATATCTAAAGGAGTCGTAGCCCTCTC LYM207 LYM207_EF_BamHI (SEQ IDNO: 3966) AAAGGATCCACTCTTCCAACCGCTCCTC LYM207_ER_KpnI (SEQ ID NO: 4200)AAAGGTACCCTAGTCTTGCGAAGTGCGAG LYM208 BamHI, XhoI LYM208_F2_BamHI (SEQ IDNO: 3968) AAAGGATCCTGCGGCTGAGTACAGACGAC LYM208_R2_KpnI (SEQ ID NO: 3969)AAAGGTACCCATCAATCCATGCTAATGTAGAGC LYM21 EcoRV, KpnI LYM21_NF_EcoRV (SEQID NO: 3970) AAAGATATCTCTCGCAGCACAAAGATGG LYM21 NR KpnI (SEQ ID NO:3971) ATAGGTACCTCACCCTTAGTTCTTCACAGTGGTG LYM212 SalI, XbaILYM212_NF_SalI (SEQ ID NO: 3972) AAAGTCGACCTGATACCCATCCATCCACCLYM212_EF_SalI (SEQ ID NO: 3973) AAAGTCGACACTGACAAACCGGACCCACLYM212_NR_XbaI (SEQ ID NO: 3974) AAATCTAGACTAGCAGAGCCGAAGTAGTACGAGLYM212_ER_XbaI (SEQ ID NO: 3975) AAATCTAGACTAGAACGAAGTAGTACGAGCAAGCLYM213 BamHI, XhoI LYM213_EF_BamHI (SEQ ID NO: 3976)AAAGGATCCCAGCTCATCAGAACACAGAAGG LYM213_ER_XhoI (SEQ ID NO: 3977)AAACTCGAGTTCGACAATTTGCAATAGAAAG LYM215 BamHI, XhoI LYM215_F2_BamHI (SEQID NO: 3978) AATGGATCCTTCCCTCCCACCGAAATG LYM215_F2_BamHI (SEQ ID NO:3978) AATGGATCCTTCCCTCCCACCGAAATG LYM215_R2_XhoI (SEQ ID NO: 3979)AAACTCGAGGAGCATGCAAAATGGACTAGACT LYM215_R2_XhoI (SEQ ID NO: 3979)AAACTCGAGGAGCATGCAAAATGGACTAGACT LYM217 SalI, XbaI LYM217_F2_SalI (SEQID NO: 4201) AAAGTCGACCGACCGATCCAAGTAGTGAGC LYM217_R2_XbaI (SEQ ID NO:4202) AAATCTAGAAGCTGATAGGCCAGTCAATCC LYM219 BamHI, KpnI LYM219_F_BamHI(SEQ ID NO: 3980) AAAGGATCCTAGCAGTCTCGATGGCCG LYM219_F_BamHI (SEQ ID NO:3980) AAAGGATCCTAGCAGTCTCGATGGCCG LYM219_R_KpnI (SEQ ID NO: 3981)TTTGGTACCCGAGTCAGCTTTTGTAATGATAG LYM219_R_KpnI (SEQ ID NO: 3981)TTTGGTACCCGAGTCAGCTTTTGTAATGATAG LYM22 SalI, XbaI LYM22_NF_SalI (SEQ IDNO: 3982) AAAGTCGACTTAGCACACATGGCGTCTTC LYM22_EF_SalI (SEQ ID NO: 3983)AAAGTCGACCATCGGCATCTTCCTAACTG LYM22_NR_XbaI (SEQ ID NO: 3984)AATTCTAGATAATCTGTAGATGGCTGCCG LYM22_ER_SmaI (SEQ ID NO: 3985)AATCCCGGGTAACAACGTACATGCAAGTCATC LYM220 BamHI, EcoRV LYM220_NF_BamHI(SEQ ID NO: 3986) AAAGGATCCCGACTTCAAGCATCAGACTACC LYM220_EF_BamHI (SEQID NO: 3987) AAAGGATCCAGCACACACATCCTCTAAGTGC LYM220_NR_EcoRV (SEQ ID NO:3988) AAAGATATCAACAGCAGTCACTTCACTCGTC LYM220_ER_EcoRV (SEQ ID NO: 3989)AAAGATATCAAGTGGTACGGCTGAGTGTAAC LYM221 BamHI, XhoI LYM221_NF_BamHI (SEQID NO: 3990) AAAGGATCCACTGTCCACTGCGTCTGTCTC LYM221_EF_BamHI (SEQ ID NO:3991) AAAGGATCCATCGTTAGAGGCTCAGAGTCAG LYM221_NR_XhoI (SEQ ID NO: 3992)AAACTCGAGACTACGTATTACACGGAGGTGG LYM221_ER_XhoI (SEQ ID NO: 3993)AAACTCGAGTCTGCAGCATTCCTTAACCTAC LYM223 XhoI, SacI LYM223_NF_XhoI (SEQ IDNO: 3994) AAACTCGAGACCTGCCTGCCACTATACTATC LYM223_EF_XhoI (SEQ ID NO:3995) AAACTCGAGAGACCCGTCTTAACTCTACCTG LYM223_NR_SacI (SEQ ID NO: 3996)AAAGAGCTCAGCACCGGTTGATCTAGAATAC LYM223_ER_SacI (SEQ ID NO: 3997)AAAGAGCTCATTTATCCACGAACCCATATTC LYM224 BamHI, XhoI LYM224_EF_BamHI (SEQID NO: 3998) AAAGGATCCCAGGCCTCACGTGTCATTC LYM224_EF_BamHI (SEQ ID NO:3998) AAAGGATCCCAGGCCTCACGTGTCATTC LYM224_R2_XhoI (SEQ ID NO: 3999)AAACTCGAGGTTTCCAGCCAACCAGAACAC LYM224_ER_XhoI (SEQ ID NO: 4000)AAACTCGAGGATCCAAATTGGTAATGCTTTG LYM228 LYM228_NF_BamHI (SEQ ID NO: 4001)AAAGGATCCGCAAGCACTCCACTTCAAGC LYM228_F2_BamHI (SEQ ID NO: 4002)AAAGGATCCCTCGAAGTGTCCAAGAAGAACACA LYM228_R2_KpnI (SEQ ID NO: 4003)TAAGGTACCGAGCTGCAAACATAACGTCGAG LYM228_R2_KpnI (SEQ ID NO: 4003)TAAGGTACCGAGCTGCAAACATAACGTCGAG LYM23 BamHI, KpnI LYM23_NF_BamHI (SEQ IDNO: 4004) AAAGGATCCTCATCTCTCTCCCTCTCATCG LYM23_NR_KpnI (SEQ ID NO: 4005)AAAGGTACCGTGCTGCTTCAACTATCCTCTC LYM232 LYM232_EF_BamHI (SEQ ID NO: 4006)AAAGGATCCAAATTCCCAATTTCTTCGGTC LYM232_ER_XhoI (SEQ ID NO: 4007)AAACTCGAGAGCACACACAGGTTCCTAAGAG LYM236 SalI, XbaI LYM236_F_SalI (SEQ IDNO: 4008) AAAGTCGACGACTACCAATCCAATCTCCTCC LYM236_ER_XbaI (SEQ ID NO:4009) AAATCTAGAAGAAATGTATAATCGAAGTGCATC LYM238 LYM238_EF_SmaI (SEQ IDNO: 4010) AAACCCGGGTAGTGGTGGAGAGACGAAACAC LYM238_ER_SacI (SEQ ID NO:4011) AAAGAGCTCCTACAAGTGCTGACTGCTGAAG LYM239 BamHI, XhoI LYM239_EF_BamHI(SEQ ID NO: 4012) AAAGGATCCCTTGGTCCGTCTCCACTCTC LYM239_R_XhoI (SEQ IDNO: 4013) AAACTCGAGCTAGGATTGGTACTCATTTCTTTGTG LYM24 SalI, XbaILYM24_NF_SalI (SEQ ID NO: 4014) AACGTCGACTCTTCTCTTTCTCTTCTCCTCGLYM24_NR_XbaI (SEQ ID NO: 4015) ATATCTAGACATTCCAAACATTGTTATCAAAC LYM240BamHI, KpnI LYM240_NF_BamHI (SEQ ID NO: 4016)AAAGGATCCTACTGTAAGCAGTTTCCCACC LYM240_EF_BamHI (SEQ ID NO: 4017)AAAGGATCCAACAACGCTCGTACTGTAAGC LYM240_NR_KpnI (SEQ ID NO: 4018)AAAGGTACCACAAGTCATTCTACCAAGCACC LYM240_ER_KpnI (SEQ ID NO: 4019)AAAGGTACCATACTTTCCTTGCTCTGCTGTC LYM241 , LYM241_NF_BamHI (SEQ ID NO:4020) AAAGGATCCAAACGGTTGGGAGGTTAGC LYM241_NR_XhoI (SEQ ID NO: 4021)AAACTCGAGACTGGATCAGATTGTGAAGGTG LYM242 BamHI, XhoI LYM242_NF_BamHI (SEQID NO: 4022) AAAGGATCCACGACTCCGACGAGCGAC LYM242_NR_XhoI (SEQ ID NO:4023) AAACTCGAGAACTCAAGTGGACAAATGTTGC LYM243 BamHI, XhoI LYM243_EF_BamHI(SEQ ID NO: 4024) AAAGGATCCAGAAGCGTAGAGCGGTCAAG LYM243_ER_XhoI (SEQ IDNO: 4025) AAACTCGAGCATTAAGCGAATTAACCATGTG LYM245 BamHI, KpnILYM245_F_BamHI (SEQ ID NO: 4026) AAAGGATCCGCTAGCTACTAGCAAATTGAAGCLYM245_F_BamHI (SEQ ID NO: 4026) AAAGGATCCGCTAGCTACTAGCAAATTGAAGCLYM245_NR_KpnI (SEQ ID NO: 4027) AAAGGTACCGGTCACCCGTTAGACTTATGCLYM245_ER_KpnI (SEQ ID NO: 4028) AAAGGTACCTGGTAAATTATGGGTATTCAGC LYM248BamHI, EcoRV LYM248_F_BamHI (SEQ ID NO: 4029)AAAGGATCCACCACCGCTCGTCTCCAC LYM248_NR_EcoRV (SEQ ID NO: 4030)AAAGATATCACAAGAGAGATGGTGTGTCAGC LYM249 LYM249_EF_BamHI (SEQ ID NO: 4031)AAAGGATCCGGGTGTCATCAAACGGACTAC LYM249_ER_KpnI (SEQ ID NO: 4032)AAAGGTACCCTAAACGAGGTTACGGAATGTGTC LYM250 SalI, XbaI LYM250_EF_SalI (SEQID NO: 4033) AAAGTCGACGGAATTGGTGAGGTGATGC LYM250_ER_XbaI (SEQ ID NO:4034) AAATCTAGACAGATAAACCTCAATCAAAGTCG LYM251 LYM251_NF_SalI (SEQ ID NO:4035) AAAGTCGACCTGTCCTCTACTACGCATCTCTC LYM251_NR_XbaI (SEQ ID NO: 4036)AAATCTAGATAATCATCATTGTAGCAGGCAC LYM252 BamHI, KpnI LYM252_NF_BamHI (SEQID NO: 4037) AAAGGATCCTAGGAAGGATGGTACTGGCTG LYM252_EF_BamHI (SEQ ID NO:4038) AAAGGATCCGCGATAGGAAGGATGGTACTG LYM252_NR_KpnI (SEQ ID NO: 4039)AAAGGTACCAGGCAAACACAATGATTTCAAC LYM252_ER_KpnI (SEQ ID NO: 4040)AAAGGTACCTGTAACATAAGTACCGGGCAG LYM254 LYM254_EF_SalI (SEQ ID NO: 4041)AAAGTCGACAATCTCCCACGCTCCAAAG LYM254_ER_XbaI (SEQ ID NO: 4042)AAATCTAGAAGTTACATTCTTGACCAGCAGC LYM255 BamHI, XhoI LYM255_NF_BamHI (SEQID NO: 4043) AAAGGATCCCTTCTAGTAGCACAGTAGTAGCAGC LYM255_NR_XhoI (SEQ IDNO: 4044) AAACTCGAGAACGAGGAAGAATCGGTATATG LYM256 BamHI, XhoILYM256_NF_BamHI (SEQ ID NO: 4045) AAAGGATCCGGAACAACTCGTAGCCATGACLYM256_EF_BamHI (SEQ ID NO: 4046) TATGGATCCCAATTTGAGAGCATTTGCTACGLYM256_NR_XhoI (SEQ ID NO: 4047) TAACTCGAGCTGAACTTAATAGCAATTCCGTAGCLYM256_ER_XhoI (SEQ ID NO: 4048) AAACTCGAGCGCACTACTGTGCTTCTGAAC LYM26SalI, XbaI LYM26_EF_SalI (SEQ ID NO: 4049)AAAGTCGACTTGCTCCCTCTCTCTCTCTTG LYM26_ER_XbaI (SEQ ID NO: 4050)AAATCTAGATGTATTCACGAGGTAAACAACG LYM260 LYM260_NF_BamHI (SEQ ID NO: 4051)AAAGGATCCGAGAGATTAATTAAGTGGCAGG LYM260_EF_BamHI (SEQ ID NO: 4052)AAAGGATCCAGAAGAGAGATTAATTAAGTGGCAG LYM260_NR_KpnI (SEQ ID NO: 4053)AAAGGTACCCTAATATCGATCCAAACTCACACAAG LYM260_ER_KpnI (SEQ ID NO: 3965)AAAGGTACCTACGTGCGTATCATACATGGAG LYM261 LYM261_EF_SmaI (SEQ ID NO: 4054)AATCCCGGGTCGAGAGGTTTCATTCAGTGC LYM261_ER_KpnI (SEQ ID NO: 4055)TTTGGTACCTTATTACATTTGGATGGGCTGT LYM267 SalI, EcoRV LYM267_F_SalI (SEQ IDNO: 4056) AAAGTCGACGAGCACAGGTAGGGTTTCG LYM267_ER_EcoRV (SEQ ID NO: 4057)AAAGATATCCACTACCGAAGACTCACACGAC LYM268 LYM268_EF_XhoI (SEQ ID NO: 4058)AAACTCGAGAACCCTCGCGAATCTGAG LYM268_ER_EcoRV (SEQ ID NO: 4059)AAAGATATCTAGTTCTCCATTCAGCATCTCC LYM270 BamHI, XhoI LYM270_NF_BamHI (SEQID NO: 4060) AAAGGATCCAAAGCAGTTCCAGCCTTCC LYM270_EF_BamHI (SEQ ID NO:4061) AAAGGATCCACCAATGGCTGCCTGAGAC LYM270_NF_BamHI (SEQ ID NO: 4060)AAAGGATCCAAAGCAGTTCCAGCCTTCC LYM270_ER_XhoI (SEQ ID NO: 4062)AAACTCGAGGATTGGATATGCCACTTGATTG LYM271 BamHI, XhoI LYM271_EF_BamHI (SEQID NO: 4063) AAAGGATCCCACCTTCTTCCCAGATCAATAG LYM271_ER_XhoI (SEQ ID NO:4064) AAACTCGAGGAAACAAAGCACAGTCAGTAGTAG LYM273_S BamHI, XhoILYM273_EF_BamHI (SEQ ID NO: 4065) AAAGGATCCTACTAACAAACAGATAATCTCCACGLYM273_R2_XhoI (SEQ ID NO: 4066) ATACTCGAGAACATGTTGGAGATCTTTGATGC LYM274BamHI, XhoI LYM274_EF_BamHI (SEQ ID NO: 4067)AAAGGATCCGAGAAGCTCCACTCTTCTCCAC LYM274_ER_XhoI (SEQ ID NO: 4068)AAACTCGAGTATAATGCACAGTTATGGGCAG LYM277 LYM277_NF_SalI (SEQ ID NO: 4069)AAAGTCGACTCAACGCCCAAGCTAGATTAC LYM277_NR_SacI (SEQ ID NO: 4070)AAAGAGCTCCTCAACATTGCAACAACTATGG LYM278 SalI, SacI LYM278_EF_SalI (SEQ IDNO: 4071) AAAGTCGACGCAGCCACACAACACTATCTC LYM278_ER_SacI (SEQ ID NO:4072) AAAGAGCTCTTGACGATACATAGCACATAAGG LYM283 LYM283_NF_SmaI (SEQ ID NO:4073) TTTCCCGGGTGCCACTTGTGCGAGGAG LYM283_R_KpnI (SEQ ID NO: 4074)AACGGTACCTCACCAATCAAAATGTACAATCATGT LYM284 BamHI, KpnI LYM284_EF_BamHI(SEQ ID NO: 4075) AAAGGATCCGAGCAACCACCCGTAGTCAG LYM284_ER_KpnI (SEQ IDNO: 4076) AAAGGTACCACAGCTCAAGTGCTCATTTCTC LYM285 XhoI, EcoRVLYM285_NF_XhoI (SEQ ID NO: 4077) AAACTCGAGCCGCCATCTACTCGGAGCLYM285_EF_XhoI (SEQ ID NO: 4078) AAACTCGAGCCTCCTCCGCCATCTACTCLYM285_NR_EcoRV (SEQ ID NO: 4079) AAAGATATCAGAATTCACACTGTCCCAACACLYM285_ER_EcoRV (SEQ ID NO: 4080) AAAGATATCCAGTTATTATAGGCCTCGTTCC LYM287XhoI, EcoRV LYM287_EF_XhoI (SEQ ID NO: 4081)AAACTCGAGTGATTGCGTTTCCTTAAATATG LYM287_ER_EcoRV (SEQ ID NO: 4082)AAAGATATCCAATCAATCCTACAAACACAGC LYM288 XhoI, SacI LYM288_EF_XhoI (SEQ IDNO: 4083) AAACTCGAGTGTTAGGAAGTGAGGACTGAGC LYM288_ER_SacI (SEQ ID NO:4084) AAAGAGCTCGCTCAATTATTCACCATTTCATC LYM289 SalI, XbaI LYM289_EF_SalI(SEQ ID NO: 4085) AAAGTCGACGCACAACCCTTGGAGACTTC LYM289_ER_XbaI (SEQ IDNO: 4086) AAATCTAGATCCTCTCATCGAGCTAAGACAC LYM290 BamHI, KpnILYM290_EF_BamHI (SEQ ID NO: 4087) AAAGGATCCATCCGGATCTCCACATTCCLYM290_ER_KpnI (SEQ ID NO: 4088) AAAGGTACCGAAACAATCTCATGGTCTCTGC LYM291SalI, BamHI LYM291_EF_SalI (SEQ ID NO: 4089)AAAGTCGACACTGAGCTCTCTGCTAAGTTGG LYM291_ER_BamHI (SEQ ID NO: 4090)AAAGGATCCTCCTAGCAACAGAAGATCCAAG LYM293 XhoI, SacI LYM293_NF_XhoI (SEQ IDNO: 4091) AAACTCGAGAGCTTCCTCCCTAGCTGTCC LYM293_EF_XhoI (SEQ ID NO: 4092)AAACTCGAGGTGTAGCTTCCTCCCTAGCTG LYM293_NR_SacI (SEQ ID NO: 4093)AAAGAGCTCCTATTCCAGGAGAAGAACAATAAGAG LYM293_ER_SacI (SEQ ID NO: 4094)AAAGAGCTCCTATTCATGTTCCAGGAGAAGAAC LYM3 XhoI, KpnI LYM3_EF_XhoI (SEQ IDNO: 4095) AATCTCGAGATTTATCTGCTTCAATGGCAAC LYM3_ER_KpnI (SEQ ID NO: 4096)ATAGGTACCCTAAGCATCATTCTGCCTACC LYM30 SalI, XhoI LYM30_NF_SalI (SEQ IDNO: 4097) AAAGTCGACCCTCCATCCTTCAGTAATTGG LYM30_NR_XhoI (SEQ ID NO: 4098)TTTCTCGAGTCAGTCTCCTTGGATGTTTGAGTTG LYM31 SalI, XhoI LYM31_NF_SalI (SEQID NO: 4099) AAGGTCGACACTCCCAACGTCTACTCTTCC LYM31_EF_SalI (SEQ ID NO:4100) AATGTCGACCTCACCACTCCCAACGTCTAC LYM31_NR_XhoI (SEQ ID NO: 4101)AAACTCGAGATGTAAGAATGAAATCTTGTAGCTC LYM31_ER_XhoI (SEQ ID NO: 4102)AATCTCGAGTGCAAGGATGTAAGAATGAAATC LYM34 BamHI, KpnI LYM34_NF_BamHI (SEQID NO: 4103) AAAGGATCCGAGATAATTAGCTCACTCCATGG LYM34_NR_KpnI (SEQ ID NO:4104) TATGGTACCGAATTGGGCCTATGAGACG LYM35 SalI, XbaI LYM35_NF_SalI (SEQID NO: 4105) AAAGTCGACAACACCTCTCTGGCTCTCTCC LYM35_NR_SacI (SEQ ID NO:4106) AAAGAGCTCTCCTAAGACTTTCTCAGCCATC LYM37 SalI, XbaI LYM37_NF_SalI(SEQ ID NO: 4203) AAAGTCGACAAAGTTAGCGACCAAGAAACC LYM37_NR_XbaI (SEQ IDNO: 4204) AAATCTAGACATTTCTTTTGGATGGATGAAC LYM4 EcoRV, KpnI LYM4_NF_EcoRV(SEQ ID NO: 4107) AAAGATATCACCTCGAAACCCTAGATCG LYM4_EF_EcoRV (SEQ ID NO:4108) AAAGATATCATTCCTCGACCAGCTCACG LYM4_NR_Kpn (SEQ ID NO: 4109)TTAGGTACCACTCAAAGGAGAGCTTCAGCC LYM4 ER KpnI (SEQ ID NO: 4110)TAAGGTACCGTTGGCATTCTTCAAACCAG LYM40 LYM40_NF_SalI (SEQ ID NO: 4111)AAAGTCGACCTCGAGAGCTCAATGATTCG LYM40_NR_XbaI (SEQ ID NO: 4112)AAATCTAGAACCAACCAATTAAAGGCTAATG LYM41 SalI, XbaI LYM41_NF_SalI (SEQ IDNO: 4113) AAAGTCGACGATTGGTTGCTTGGGTTTG LYM41_NR_XbaI (SEQ ID NO: 4114)AAATCTAGATGCTTTCTTTCAGAACATCTCC LYM42 SalI, XbaI LYM42_NF_SalI (SEQ IDNO: 4115) AAAGTCGACAACCTCTCCTCCTCGTCACAC LYM42_EF_SalI (SEQ ID NO: 4116)AAAGTCGACATCAAACCTCTCCTCCTCGTC LYM42_NR_XbaI (SEQ ID NO: 4117)AATTCTAGATCACAGGAAGGAGGGGTAGTAACAG LYM42_ER_XbaI (SEQ ID NO: 4118)AAATCTAGAATTTCCTGCTGTTCATTCAAAG LYM43 SalI, XbaI LYM43_NF_SalI (SEQ IDNO: 4119) AAAGTCGACTCAGTGTTCTTCCATTCTTTCC LYM43_NR_XbaI (SEQ ID NO:4120) AAATCTAGATTGAATTAGCAGCAGCAAGAG LYM44 SalI, XbaI LYM44_NF_SalI (SEQID NO: 4121) AAAGTCGACCGAACTAACTAACCATCTCATCC LYM44_NR_XbaI (SEQ ID NO:4122) AAATCTAGAATCGTTCGATTATTATTGCTCC LYM5 EcoRV, PstI LYM5_EF_EcoRV(SEQ ID NO: 4123) AAAGATATCTCCTCTTCTCAAACTCCATCTC LYM5_ER_PstI (SEQ IDNO: 4124) AATCTGCAGGGTCCTGTCATGCTGTGTAGTC LYM51 SalI, XbaI LYM51_EF_SalI(SEQ ID NO: 4125) AAAGTCGACAATTCACCTCCCAAGCAGAG LYM51_ER_XbaI (SEQ IDNO: 4126) AAATCTAGAATACAAGGCCTGCACTACCTAC LYM52 EcoRV, XhoI LYM52_F_XhoI(SEQ ID NO: 4127) AAACTCGAGAAACCCGATAAGAAAATGGC LYM52_ER_EcoRV (SEQ IDNO: 4128) TTTGATATCCTAGTGCCATACGTGCCTAACCT LYM53 SalI, XbaILYM53_NF_SalI (SEQ ID NO: 4129) AAAGTCGACATCCTCTCTTTCCACTCCTAGCLYM53_NR_XbaI (SEQ ID NO: 4130) AAATCTAGATAGCACTCAGCTTAATTGGATG LYM56SalI, XbaI LYM56_F_SalI (SEQ ID NO: 4131) AAAGTCGACCTCGCTTGCCCACTCCTTLYM56_F_SalI (SEQ ID NO: 4131) AAAGTCGACCTCGCTTGCCCACTCCTT LYM56_NR_XbaI(SEQ ID NO: 4132) AAATCTAGACTAGCATGATCCTGGATGTTTACTC LYM56_ER_XbaI (SEQID NO: 4133) AAATCTAGAAGCAGAGATAGGCATAAGTCCA LYM57 EcoRV, XhoILYM57_NF_EcoRV (SEQ ID NO: 4134) AAAGATATCACCACTAGGACTCAACGAGAAGLYM57_NR_XhoI (SEQ ID NO: 4135) AACCTCGAGAGTAACATCCGAACGTATACACC LYM6SmaI, KpnI LYM6_NF_X/SmaI (SEQ ID NO: 4136) ATACCCGGGAACCACGCGAAGACATGGLYM6_NR_KpnI (SEQ ID NO: 4137) TATGGTACCGGATCAGGTTATACTTCTTATTGAC LYM61BamHI, XhoI LYM61_NF_BamHI (SEQ ID NO: 4138)AAAGGATCCAAGCCTGTTCTCTGTCGATTG LYM61_NR_XhoI (SEQ ID NO: 4139)AAACTCGAGAATGCATGTCCTAGTCTTTACG LYM62 BamHI, KpnI LYM62_NF_BamHI (SEQ IDNO: 4140) TTAGGATCCAACATTTACGCGATCCATTG LYM62_EF_BamHI (SEQ ID NO: 4141)TTAGGATCCATCATCTGCTTTGTCTACCTCG LYM62_NR_KpnI (SEQ ID NO: 4142)ATCGGTACCTCAACTGAATTCGCTGAAACTTGTC LYM62_ER_KpnI (SEQ ID NO: 4143)AAAGGTACCGAAAACAAATGGAAGCAATCTG LYM66 EcoRV, XhoI LYM66_NF_EcoRV (SEQ IDNO: 4144) AAAGATATCGAGACGCAAGAAACATAGCTC LYM66_NR_XhoI (SEQ ID NO: 4145)AAACTCGAGCAATCACTGCTACAAATCCGT LYM67 SalI, XbaI LYM67_NF_SalI (SEQ IDNO: 4146) TATGTCGACTCTTCTTCACTGAGGCAAGTTC LYM67_NR_XbaI (SEQ ID NO:4147) AAGTCTAGATCAAAGATCCATAACATTCCATGC LYM68 SalI, XhoI LYM68_NF_SalI(SEQ ID NO: 4148) ATTGTCGACTTGAGATAAAGGCAAAATTACG LYM68_EF_SalI (SEQ IDNO: 4149) TTTGTCGACGTCTCGTTTCAGATTCTTCTGC LYM68_NR_XhoI (SEQ ID NO:4150) TTCCTCGAGTCTCTAGAGTTGCATTCCTTCC LYM68_ER_XhoI (SEQ ID NO: 4151)TGACTCGAGCATCGTTTACACTGAACCACTG LYM69 SalI, XbaI LYM69_NF_SalI (SEQ IDNO: 4152) AAAGTCGACACCCAGGAACACATCATCATC LYM69_NR_XbaI (SEQ ID NO: 4153)AAATCTAGAAGGACACGTCAAATGAGAAAAC LYM7 SalI, XbaI LYM7_NF_SalI (SEQ ID NO:4154) AAAGTCGACAGTCAGATCCATTCCTCCTCC LYM7_NR_XbaI (SEQ ID NO: 4155)AATTCTAGAAAAAGTAGCAGCCGGTCATC LYM73 LYM73_EF_SalI (SEQ ID NO: 4156)AACGTCGACAATCTTGACACCATCTCGCTC LYM73_ER_StuI (SEQ ID NO: 4157)TTTAGGCCTCTCGCACATTATTTTGTACAGC LYM79 SalI, XbaI LYM79_F_SalI (SEQ IDNO: 4158) AAAGTCGACGCGACAGAGAATCCATGGC LYM79_F_SalI (SEQ ID NO: 4158)AAAGTCGACGCGACAGAGAATCCATGGC LYM79_NR_XbaI (SEQ ID NO: 4159)AATTCTAGATCAAACTCCTCTTATATGCACCTGC LYM79_ER_XbaI (SEQ ID NO: 4160)AAATCTAGATCAGAAACTAACTCCTCTTATATGCACC LYM8 XhoI, KpnI LYM8 NF XhoI (SEQID NO: 4161) ATACTCGAGCTTCCCCGATAGAAATCCATC LYM8 NR KpnI (SEQ ID NO:4162) TAGGGTACCACCAAACAGCACATATGCGG LYM82 SalI, XbaI LYM82_EF_SalI (SEQID NO: 4163) AAAGTCGACCGCAACCGGAGAGAAATC LYM82_ER_XbaI (SEQ ID NO: 4164)AAATCTAGATCGACAATCTTCATACACAACG LYM83 LYM83_NF_BamHI (SEQ ID NO: 4165)AAAGGATCCCGACAGTCACCACTCACCAAC LYM83_F2_BamHI (SEQ ID NO: 4166)AAAGGATCCTCCGCACGCAACTCAGTG LYM83_R2_XhoI (SEQ ID NO: 4167)AAACTCGAGCAACGGTAACACACAAGCATTC LYM83_R2_XhoI (SEQ ID NO: 4167)AAACTCGAGCAACGGTAACACACAAGCATTC LYM84 BamHI, XhoI LYM84_NF_BamHI (SEQ IDNO: 4168) AAAGGATCCACCCAGAACCCGAAGAATG LYM84_F2_BamHI (SEQ ID NO: 4169)AATGGATCCTAAACCCAGAACCCGAAGAATG LYM84_R2_XhoI (SEQ ID NO: 4170)AAACTCGAGCAAACTGGAGCATAGCAACTAGG LYM84_R2_XhoI (SEQ ID NO: 4170)AAACTCGAGCAAACTGGAGCATAGCAACTAGG LYM86 BamHI, XhoI LYM86_EF_BamHI (SEQID NO: 4171) AAAGGATCCCACACACCACAGTCGCAATC LYM86_ER_XhoI (SEQ ID NO:4172) AAACTCGAGAGAATCGATGCAGGTAACTACG LYM88 BamHI, XhoI LYM88_F_BamHI(SEQ ID NO: 4173) AAAGGATCCACAATAAACAAGATAAATGGAGG LYM88_F_BamHI (SEQ IDNO: 4173) AAAGGATCCACAATAAACAAGATAAATGGAGG LYM88_NR_XhoI (SEQ ID NO:4174) AAACTCGAGTCACACGCAACTTCAGGTTC LYM88_ER_XhoI (SEQ ID NO: 4175)AAACTCGAGCAAACCGAATTATTACATCAGG LYM89 SalI, SacI LYM89_NF_SalI (SEQ IDNO: 4176) AAAGTCGACGGCCGACACATCTGATCTAAC LYM89_NR_SacI (SEQ ID NO: 4177)AAAGAGCTCTCCCAGAAATATATAAGAACAAGC LYM9 SalI, XbaI LYM9_NF_SalI (SEQ IDNO: 4178) AAAGTCGACAACTCCCCAACCAAGCAG LYM9_NR_XbaI (SEQ ID NO: 4179)AAATCTAGATTAGTACTAAGAGTCGGCTTTGGC LYM90 SalI, XbaI LYM90_NF_SalI (SEQ IDNO: 4180) AAAGTCGACCTAAACCCTAACCCTAGATTGG LYM90_NR_XbaI (SEQ ID NO:4181) AAATCTAGAAGACTTGGCTAATGCTAACCTG LYM91 SalI, XbaI LYM91_F2_SalI(SEQ ID NO: 4182) TAAGTCGACCGTCTCTCAAGCTCGCAGC LYM91_F2_SalI (SEQ ID NO:4182) TAAGTCGACCGTCTCTCAAGCTCGCAGC LYM91_R2_XbaI (SEQ ID NO: 4183)ATTTCTAGACGAGAGCCTCTAATGGATCACAG LYM91_R2_XbaI (SEQ ID NO: 4183)ATTTCTAGACGAGAGCCTCTAATGGATCACAG LYM93 LYM93_EF_SalI (SEQ ID NO: 4184)AAAGTCGACATTGCACTGCATAGGGCTG LYM93_ER_XbaI (SEQ ID NO: 4185)AAATCTAGACTAAGAGTTGAGCATGATAAATACGAC LYM95 SalI, XbaI LYM95_NF_SalI (SEQID NO: 4186) ATAGTCGACGAGAAAGTGGAAGAGAACATGG LYM95_EF_SalI (SEQ ID NO:4187) AAAGTCGACCCGCTGGAGAAAGTGGAAG LYM95_NR_XbaI (SEQ ID NO: 4188)AAATCTAGAGTCCACAGATCCATGTCAAATC LYM95_ER_XbaI (SEQ ID NO: 4189)AAATCTAGAGTGAATTTGATTTATTGCCAAC LYM99 BamHI, KpnI LYM99_NF_BamHI (SEQ IDNO: 4190) AAAGGATCCCCGACCACGGATTGATTC LYM99_EF_BamHI (SEQ ID NO: 4191)AAAGGATCCTTGACTTGGGTGTCTGGTCC LYM99_NR_KpnI (SEQ ID NO: 4192)AAAGGTACCGTGCCTATGTCTTCCTAGCATC LYM99_ER_KpnI (SEQ ID NO: 4193)AAAGGTACCATATTTAGGCGCCAGTAAAGAC Table 26. Provided are the PCR primersused for cloning the genes of some embodiments of the invention. Fwd= forward primer; Rev = reverse primer; Nested = nested primer for PCR(internal primer); External = external primer for PCR.

To facilitate cloning of the cDNAs/genomic sequences, a 8-12 byextension was added to the 5′ of each primer. The primer extensionincludes an endonuclease restriction site. The restriction sites wereselected using two parameters: (a). The site did not exist in the cDNAsequence; and (b). The restriction sites in the forward and reverseprimers were designed such that the digested cDNA is inserted in thesense formation into the binary vector utilized for transformation.

Each digested PCR product was inserted into a high copy vectorpBlue-script KS plasmid vector [pBlue-script KS plasmid vector,Hypertext Transfer Protocol://World Wide Web (dot) stratagene (dot)com/manuals/212205 (dot) pdf] or into plasmids originating from thisvector. In cases where the pGXN/pGXNa high copy vector (originated frompBlue-script KS) was used, the PCR product was inserted upstream to theNOS terminator (SEQ ID NO: 4194) originated from pBI 101.3 binary vector(GenBank Accession No. U12640, nucleotides 4356 to 4693) and downstreamto the 35S promoter. The digested products and the linearized plasmidvector were ligated using T4 DNA ligase enzyme (Roche, Switzerland). Insome cases PCR products were cloned without digestion into pCR-BluntII-TOPO vector (Invitrogen).

Sequencing of the amplified PCR products was performed, using ABI 377sequencer (Amersham Biosciences Inc). In all cases, after confirmationof the sequence of the cloned genes, the cloned cDNA accompanied or notwith the NOS terminator was introduced into the modified pGI binaryvector containing the 6669 promoter [pQFN or pQYN_(—)6669] according toTable 27, via digestion with appropriate restriction endonucleases. Inany case the insert was followed by single copy of the NOS terminator(SEQ ID NO:4194).

High copy plasmids containing the cloned genes were digested withrestriction endonucleases (New England BioLabs Inc) and cloned intobinary vectors according to Table 27, below.

Binary Vectors Used for Cloning:

Evolution of binary vectors construction: The plasmid pPI wasconstructed by inserting a synthetic poly-(A) signal sequence,originating from pGL3 basic plasmid vector (Promega, Acc No U47295; by4658-4811) into the HindIII restriction site of the binary vectorpBI101.3 (Clontech, Acc. No. U12640). pGI (pBXYN) is similar to pPI, butthe original gene in the backbone, the GUS gene, was replaced by theGUS-Intron gene followed by the NOS terminator (SEQ ID NO:4194)(Vancanneyt. G, et al MGG 220, 245-50, 1990). The modified pGI vector(pQXYN) is a modified version of the pGI vector in which the cassette isinverted between the left and right borders so the gene and itscorresponding promoter are close to the right border and the NPTII geneis close to the left border.

Vectors used for cloning the polynucleotides of some embodiments of theinvention: Cloned genes were digested from the high copy vectors andcloned into one of the following binary vectors: pQFN or pQYN_(—)6669.

pQFN (see FIG. 2) and pQYN_(—)6669 (see FIG. 1) are modified pGI vectorsin which the 35S promoter was replaced by the new At6669 promoter (SEQID NO:4198). pQYN_(—)6669 contains the GUSintron sequence, while pQFNlacks the GUSintron sequence

TABLE 27 Restriction enzyme sites used to clone identified genesaccording to some embodiments of the invention into binary vectorsRestriction Restriction enzymes enzymes used for used for cloning intocloning into Restriction enzymes used Binary binary vector- binaryvector- for digesting the binary Gene name vector FORWARD REVERSE vectorLYM1 pQFN SalI EcoRI SalI, EcoRI LYM10 pQFN XhoI KpnI XhoI, KpnI LYM100pQYN_6669 SalI EcoRI SalI, EcoRI LYM102 pQFN BamHI XhoI BamHI, XhoILYM103 pQFN BamHI XhoI BamHI, XhoI LYM105 pQFN BamHI XhoI BamHI, XhoILYM106 pQYN_6669 SalI EcoRI SalI, EcoRI LYM107 pQFN BamHI XhoI BamHI,XhoI LYM109 pQFN XhoI StuI XhoI, StuI LYM110 pQFN BamHI XhoI BamHI, XhoILYM111 pQFN XhoI EcoRI XhoI, EcoRI LYM112 pQFN BamHI XhoI BamHI, XhoILYM113 pQYN_6669 SalI EcoRI SalI, EcoRI LYM115 pQFN BamHI XhoI BamHI,XhoI LYM116 pQYN_6669 SalI EcoRI SalI, EcoRI LYM117 pQFN BamHI EcoRVBamHI, StuI LYM118 pQFN BamHI XhoI BamHI, XhoI LYM119 pQYN_6669 SalIEcoRI SalI, EcoRI LYM12 pQFN XhoI KpnI XhoI, KpnI LYM120 pQFN BamHI XhoIBamHI, XhoI LYM121 pQFN BamHI XhoI BamHI, XhoI LYM122_G pQFN BamHI XhoIBamHI, XhoI LYM122_S pQFN BamHI XhoI BamHI, XhoI LYM123 pQFN BamHI XhoIBamHI, XhoI LYM125 pQFN BamHI KpnI BamHI, KpnI LYM126 pQFN BamHI KpnIBamHI, KpnI LYM127 pQFN BamHI XhoI BamHI, XhoI LYM128 pQFN BamHI XhoIBamHI, XhoI LYM129 pQFN SalI EcoRI SalI, EcoRI LYM13 pQFN SalI BamHISalI, BamHI LYM130 pQYN_6669 SalI EcoRI SalI, EcoRI LYM131 pQFN SalIXhoI SalI, XhoI LYM132 pQFN BamHI XhoI BamHI, XhoI LYM134 pQFN BamHIXhoI BamHI, XhoI LYM135 pQFN SalI KpnI SalI, KpnI LYM136 pQFN BamHI KpnIBamHI, KpnI LYM137 pQYN_6669 SalI EcoRI SalI, EcoRI LYM138 pQFN SalIEcl136II SalI, StuI LYM14 pQFN SalI BamHI SalI, BamHI LYM140 pQFN XhoIEcoRI XhoI, EcoRI LYM141 pQFN BamHI KpnI BamHI, KpnI LYM142 pQYN_6669SalI EcoRI SalI, EcoRI LYM143 pQYN_6669 SalI EcoRI SalI, EcoRI LYM144pQFN SalI EcoRV SalI, StuI LYM145 pQFN BamHI XhoI BamHI, XhoI LYM146pQFN KpnI KpnI KpnI, KpnI LYM147 pQFN SalI EcoRI SalI, EcoRI LYM148 pQFNBamHI XbaI BamHI, XhoI LYM149 pQYN_6669 SalI EcoRI SalI, EcoRI LYM15pQFN SalI EcoRI SalI, EcoRI LYM152 pQYN_6669 SalI EcoRI SalI, EcoRILYM153 pQYN_6669 SalI EcoRI SalI, EcoRI LYM154 pQFN XhoI StuI XhoI, StuILYM155 pQYN_6669 SalI EcoRI SalI, EcoRI LYM156 pQFN StuI StuI SmaI, SmaILYM157_G pQYN_6669 SalI EcoRI SalI, EcoRI LYM157_S pQFN SalI StuI SalI,StuI LYM159 pQYN_6669 SalI EcoRI SalI, EcoRI LYM16 pQFN SalI EcoRI SalI,EcoRI LYM160 pQYN_6669 SalI EcoRI SalI, EcoRI LYM161 pQFN BamHI XhoIBamHI, XhoI LYM162 pQFN BamHI XhoI BamHI, XhoI LYM164 pQYN_6669 SalIEcoRI SalI, EcoRI LYM165 pQFN XhoI Ecl136II XhoI, StuI LYM17 pQFN SmaIKpnI SmaI, KpnI LYM170 pQYN_6669 SalI EcoRI SalI, EcoRI LYM172 pQFNBamHI XhoI BamHI, XhoI LYM173 pQFN BamHI XhoI BamHI, XhoI LYM174 pQFNBamHI KpnI BamHI, KpnI LYM175 pQYN_6669 SalI EcoRI SalI, EcoRI LYM176pQYN_6669 SalI EcoRI SalI, EcoRI LYM178 pQYN_6669 SalI EcoRI SalI, EcoRILYM179 pQFN SalI StuI SalI, StuI LYM180 pQFN BamHI XhoI BamHI, XhoILYM181 pQFN BamHI EcoRV BamHI, StuI LYM183 pQFN SalI XbaI SalI, StuILYM184 pQFN BamHI XhoI BamHI, XhoI LYM185 pQFN BamHI KpnI BamHI, KpnILYM186 pQFN SalI Ecl136II SalI, StuI LYM188 pQFN BamHI XhoI BamHI, XhoILYM189 pQYN_6669 SalI EcoRI SalI, EcoRI LYM19 pQYN_6669 SalI EcoRI SalI,EcoRI LYM192 pQFN XhoI EcoRV XhoI, StuI LYM193 pQFN BamHI XhoI BamHI,XhoI LYM194 pQFN SalI XhoI SalI, SalI LYM196 pQFN BamHI XhoI BamHI, XhoILYM197 pQFN BamHI XhoI BamHI, XhoI LYM198 pQFN BamHI XhoI BamHI, XhoILYM2 pQFN EcoRV KpnI SmaI, KpnI LYM20 pQFN EcoRV KpnI SmaI, KpnI LYM200pQFN BamHI XhoI BamHI, XhoI LYM201 pQFN BamHI XhoI BamHI, XhoI LYM203pQFN BamHI XhoI BamHI, XhoI LYM204 pQFN BamHI XhoI BamHI, XhoI LYM206pQFN XhoI EcoRV XhoI, StuI LYM207 pQFN BamHI KpnI BamHI, KpnI LYM208pQFN BamHI KpnI BamHI, KpnI LYM21 pQFN EcoRV KpnI SmaI, KpnI LYM212pQYN_6669 SalI EcoRI SalI, EcoRI LYM213 pQFN BamHI XhoI BamHI, XhoILYM215 pQFN BamHI XhoI BamHI, XhoI LYM217 pQYN_6669 SalI EcoRI SalI,EcoRI LYM219 pQFN BamHI KpnI BamHI, KpnI LYM22 pQYN_6669 SalI EcoRISalI, EcoRI LYM220 pQFN BamHI EcoRV BamHI, StuI LYM221 pQFN BamHI XhoIBamHI, XhoI LYM223 pQFN XhoI EcoRI XhoI, EcoRI LYM224 pQFN BamHI XhoIBamHI, XhoI LYM227 pQFN BamHI KpnI BamHI, KpnI LYM228 pQFN StuI KpnIKpnI, EcoRV LYM23 pQFN BamHI KpnI BamHI, KpnI LYM232 pQFN BamHI XhoIBamHI, XhoI LYM233 pQFN BamHI XhoI BamHI, XhoI LYM234 pQFN BamHI XhoIBamHI, XhoI LYM236 pQFN SalI EcoRI SalI, EcoRI LYM238 pQFN SmaI KpnISmaI, KpnI LYM239 pQFN BamHI XhoI BamHI, XhoI LYM24 pQFN SalI EcoRISalI, EcoRI LYM240 pQFN BamHI KpnI BamHI, KpnI LYM241 pQFN BamHI XhoIBamHI, XhoI LYM242 pQFN BamHI XhoI BamHI, XhoI LYM243 pQFN BamHI XhoIBamHI, XhoI LYM245 pQFN BamHI KpnI BamHI, KpnI LYM248 pQFN BamHI EcoRVBamHI, StuI LYM249 pQFN BamHI KpnI BamHI, KpnI LYM250 pQFN SalI XbaISalI, StuI LYM251 pQFN SalI Ecl136II SalI, StuI LYM252 pQFN BamHI KpnIBamHI, KpnI LYM254 pQFN SalI BamHI SalI, BamHI LYM255 pQFN BamHI XhoIBamHI, XhoI LYM256 pQFN BamHI XhoI BamHI, XhoI LYM26 pQYN_6669 SalIEcoRI SalI, EcoRI LYM260 pQFN BamHI KpnI BamHI, KpnI LYM261 pQFN SmaIKpnI SmaI, KpnI LYM267 pQFN SalI EcoRV SalI, StuI LYM268 pQFN XhoI EcoRVXhoI, StuI LYM270 pQFN BamHI XhoI BamHI, XhoI LYM271 pQFN BamHI XhoIBamHI, XhoI LYM273_G pQFN BamHI XhoI BamHI, XhoI LYM273_S pQFN BamHIXhoI BamHI, XhoI LYM274 pQFN BamHI XhoI BamHI, XhoI LYM277 pQFN SalIEcl136II SalI, StuI LYM278 pQYN_6669 SalI EcoRI SalI, EcoRI LYM283 pQFNSmaI KpnI SmaI, KpnI LYM284 pQFN BamHI KpnI BamHI, KpnI LYM285 pQFN XhoIEcoRV XhoI, StuI LYM287 pQFN XhoI EcoRV XhoI, StuI LYM288 pQFN XhoIEcoRI XhoI, EcoRI LYM289 pQYN_6669 SalI EcoRI SalI, EcoRI LYM290 pQFNBamHI KpnI BamHI, KpnI LYM291 pQFN SalI BamHI SalI, BamHI LYM293 pQFNXhoI EcoRI XhoI, EcoRI LYM3 pQFN XhoI KpnI XhoI, KpnI LYM30 pQFN SalIXhoI SalI, XhoI LYM31 pQFN SalI XhoI SalI, XhoI LYM32 pQFN BamHI KpnIBamHI, KpnI LYM34 pQFN BamHI KpnI BamHI, KpnI LYM35 pQYN_6669 SalI EcoRISalI, EcoRI LYM36 pQFN StuI StuI StuI, StuI LYM37 pQYN_6669 SalI EcoRISalI, EcoRI LYM38 pQFN SalI BamHI SalI, BamHI LYM4 pQFN EcoRV KpnI SmaI,KpnI LYM40 pQFN SalI EcoRV SalI, StuI LYM41 pQYN_6669 SalI EcoRI SalI,EcoRI LYM42 pQYN_6669 SalI EcoRI SalI, EcoRI LYM43 pQYN_6669 SalI EcoRISalI, EcoRI LYM44 pQYN_6669 SalI EcoRI SalI, EcoRI LYM5 pQFN SalI BamHISalI, BamHI LYM51 pQYN_6669 SalI EcoRI SalI, EcoRI LYM52 pQFN XhoI EcoRVXhoI, StuI LYM53 pQYN_6669 SalI EcoRI SalI, EcoRI LYM56 pQYN_6669 SalIEcoRI SalI, EcoRI LYM57 pQFN EcoRV XhoI SmaI, XhoI LYM6 pQFN SmaI KpnISmaI, KpnI LYM61 pQFN BamHI XhoI BamHI, XhoI LYM62 pQFN BamHI KpnIBamHI, KpnI LYM66 pQFN EcoRV XhoI SmaI, XhoI LYM67 pQYN_6669 SalI EcoRISalI, EcoRI LYM68 pQFN SalI XhoI SalI, XhoI LYM69 pQYN_6669 SalI EcoRISalI, EcoRI LYM7 pQFN SalI EcoRI SalI, EcoRI LYM73 pQFN SalI StuI SalI,StuI LYM74 pQFN SalI Ecl136II SalI, StuI LYM79 pQYN_6669 SalI EcoRISalI, EcoRI LYM8 pQFN XhoI KpnI XhoI, KpnI LYM82 pQYN_6669 SalI EcoRISalI, EcoRI LYM83 pQFN BamHI XhoI BamHI, XhoI LYM84 pQFN BamHI XhoIBamHI, XhoI LYM86 pQFN BamHI XhoI BamHI, XhoI LYM88 pQFN BamHI XhoIBamHI, XhoI LYM89 pQYN_6669 SalI EcoRI SalI, EcoRI LYM9 pQFN SalI EcoRISalI, EcoRI LYM90 pQYN_6669 SalI EcoRI SalI, EcoRI LYM91 pQYN_6669 SalIEcoRI SalI, EcoRI LYM93 pQFN SalI XhoI SalI, XhoI LYM95 pQYN_6669 SalIEcoRI SalI, EcoRI LYM99 pQFN BamHI KpnI BamHI, KpnI Table 27.

TABLE 28 Genes cloned from cDNA libraries or genomic DNA in a High copynumber plasmid High copy Amplified from Polynucleotide Polypeptide GeneName plasmid Organism Origin SEQ ID NO: SEQ ID NO: LYM1 pGXN RICE OryzacDNA 3481 240 (pKG + Nos + 35S) sativa L. Japonica ND LYM10 pKS(Pks_J)RICE Oryza cDNA 3490 249 sativa L. Japonica ND LYM100 pGXN BARLEY cDNA3542 301 (pKG + Nos + 35S) Hordeum vulgare L. Manit LYM102 pKS(Pks_J)RICE Oryza cDNA 3543 302 sativa L. Japonica ND LYM103 pKS(Pks_J) MAIZEZea cDNA 3544 3689 mays L. Pioneer 30G54 LYM105 pKS(Pks_J) BARLEY cDNA3545 3690 Hordeum vulgare L. Manit LYM106 pGXN BARLEY cDNA 3546 305(pKG + Nos + 35S) Hordeum vulgare L. Manit LYM107 pKS(Pks_J) MAIZE ZeacDNA 3589 349 mays L. ND LYM109 pGXNa MAIZE Zea cDNA 3590 3702 mays L.ND LYM110 pKS(Pks_J) MAIZE Zea cDNA 3547 3691 mays L. ND LYM111 pGXNaMAIZE Zea cDNA 3548 307 mays L. Pioneer 30G54 LYM112 pKS(Pks_J) MAIZEZea cDNA 3591 3703 mays L. Pioneer 30G54 LYM113 pGXN MAIZE Zea cDNA 3592352 (pKG + Nos + 35S) mays L. Pioneer 30G54 LYM115 pKS(Pks_J) MAIZE ZeacDNA 3593 3704 mays L. ND LYM116 pGXN MAIZE Zea cDNA 3594 354 (pKG +Nos + 35S) mays L. ND LYM117 Topo B MAIZE Zea cDNA 3595 3705 mays L. NDLYM118 GeneArt 3596 356 LYM119 pGXN MAIZE Zea cDNA 3549 3692 (pKG +Nos + 35S) mays L. ND LYM12 pKS(Pks_J) RICE Oryza cDNA 3491 250 sativaL. Japonica ND LYM120 pKS(Pks_J) RICE Oryza cDNA 3550 309 sativa L.Japonica ND LYM121 pKS(Pks_J) RICE Oryza cDNA 3597 357 sativa L.Japonica ND LYM122_G Topo B RICE Oryza Genomic 3739 310 sativa L.Japonica ND LYM122_S GeneArt 3551 310 LYM123 GeneArt 3598 358 LYM125Topo B RICE Oryza cDNA 3552 311 sativa L. Japonica ND LYM126 GeneArt3553 312 LYM127 Topo B RICE Oryza cDNA 3554 313 sativa L. Japonica NDLYM128 pKS(Pks_J) RICE Oryza cDNA 3555 314 sativa L. Japonica ND LYM129pGXN RICE Oryza cDNA 3556 315 (pKG + Nos + 35S) sativa L. Indica ND +RICE Oryza sativa L. Japonica ND LYM13 pKS(Pks_J) RICE Oryza cDNA 3492251 sativa L. Japonica ND LYM130 pGXN RICE Oryza cDNA 3557 316 (pKG +Nos + 35S) sativa L. Indica ND LYM131 pGXNa RICE Oryza cDNA 3558 3693sativa L. Japonica ND LYM132 pKS(Pks_J) RICE Oryza cDNA 3559 318 sativaL. Japonica ND LYM134 pKS(Pks_J) RICE Oryza cDNA 3560 319 sativa L.Japonica ND LYM135 Topo B RICE Oryza cDNA 3599 359 sativa L. Japonica NDLYM136 pKS(Pks_J) RICE Oryza cDNA 3561 3694 sativa L. Japonica ND LYM137pGXN BARLEY cDNA 3562 321 (pKG + Nos + 35S) Hordeum vulgare L. ManitLYM138 pGXN RICE Oryza cDNA 3600 360 (pKG + Nos + 35S) sativa L.Japonica ND LYM14 pKS(Pks_J) RICE Oryza cDNA 3493 252 sativa L. JaponicaND LYM140 pGXNa BARLEY cDNA 3563 322 Hordeum vulgare L. Manit LYM141Topo B RICE Oryza cDNA 3564 323 sativa L. Japonica ND LYM142 pGXN BARLEYcDNA 3565 324 (pKG + Nos + 35S) Hordeum vulgare L. Manit LYM143 pGXNRICE Oryza cDNA 3566 325 (pKG + Nos + 35S) sativa L. Japonica ND LYM144pKS(Pks_J) RICE Oryza cDNA 3567 3695 sativa L. Japonica ND LYM145pKS(Pks_J) RICE Oryza cDNA 3568 327 sativa L. ND LYM146 Topo B MAIZE ZeaGenomic 3601 3706 mays L. ND LYM147 pGXN MAIZE Zea cDNA 3602 3707 (pKG +Nos + 35S) mays L. ND LYM148 pKS(Pks_J) BARLEY cDNA 3569 3696 Hordeumvulgare L. Manit LYM149 pGXN BARLEY cDNA 3570 329 (pKG + Nos + 35S)Hordeum vulgare L. Manit LYM15 pGXN RICE Oryza cDNA 3494 253 (pKG +Nos + 35S) sativa L. Japonica ND LYM152 pGXN ARABIDOPSIS cDNA 3571 330(pKG + Nos + 35S) Arabidopsis thaliana Transgenic Columbia LYM153 pGXNRICE Oryza cDNA 3572 331 (pKG + Nos + 35S) sativa L. Japonica ND LYM154GeneArt 3603 363 LYM155 pGXN BARLEY cDNA 3604 3708 (pKG + Nos + 35S)Hordeum vulgare L. Manit LYM156 pGXNa BARLEY cDNA 3573 332 Hordeumvulgare L. Manit LYM157_G pGXN BARLEY cDNA 3574 333 (pKG + Nos + 35S)Hordeum vulgare L. Manit LYM157_S GeneArt 3574 333 LYM159 pGXN BARLEYcDNA 3575 3697 (pKG + Nos + 35S) Hordeum vulgare L. Manit LYM16 pGXNRICE Oryza cDNA 3495 254 (pKG + Nos + 35S) sativa L. ND LYM160 pGXNBARLEY cDNA 3576 3698 (pKG + Nos + 35S) Hordeum vulgare L. Manit LYM161pKS(Pks_J) BARLEY cDNA 3577 3699 Hordeum vulgare L. Manit LYM162pKS(Pks_J) MAIZE Zea cDNA 3578 337 mays L. ND LYM164 pGXN RICE OryzacDNA 3579 3700 (pKG + Nos + 35S) sativa L. ND LYM165 Topo B MAIZE ZeacDNA 3580 339 mays L. Pioneer 30G54 LYM17 pKS(Pks_J) RICE Oryza cDNA3496 255 sativa L. ND LYM170 pGXN RICE Oryza cDNA 3581 341 (pKG + Nos +35S) sativa L. ND LYM172 pKS(Pks_J) RICE Oryza cDNA 3582 342 sativa L.Indica ND LYM173 pKS(Pks_J) RICE Oryza cDNA 3583 343 sativa L. JaponicaND LYM174 pKS(Pks_J) SORGHUM cDNA 3584 344 Sorghum bicolor Monsanto S5LYM175 pGXN RICE Oryza cDNA 3585 345 (pKG + Nos + 35S) sativa L. NDLYM176 pGXN RICE Oryza cDNA 3586 346 (pKG + Nos + 35S) sativa L.Japonica ND LYM178 pGXN ARABIDOPSIS cDNA 3587 347 (pKG + Nos + 35S)Arabidopsis thaliana ND LYM179 pGXNa MAIZE Zea cDNA 3588 3701 mays L.Pioneer 30G54 LYM180 pKS(Pks_J) BARLEY cDNA 3605 365 Hordeum vulgare L.Manit LYM181 Topo B BARLEY cDNA 3606 366 Hordeum vulgare L. Manit LYM183Topo B BARLEY cDNA 3655 3733 Hordeum vulgare L. Manit LYM184 Topo BBARLEY cDNA 3607 3709 Hordeum vulgare L. Manit LYM185 pKS(Pks_J) BARLEYcDNA 3608 369 Hordeum vulgare L. Manit LYM186 pGXN BARLEY cDNA 3609 3710(pKG + Nos + 35S) Hordeum vulgare L. Manit LYM188 pKS(Pks_J) BARLEY cDNA3610 371 Hordeum vulgare L. Manit LYM189 pGXN BARLEY cDNA 3611 3711(pKG + Nos + 35S) Hordeum vulgare L. Manit LYM19 pGXN RICE Oryza cDNA3497 256 (pKG + Nos + 35S) sativa L. Japonica ND LYM192 pKS(Pks_J)BARLEY cDNA 3612 3712 Hordeum vulgare L. Manit LYM193 pKS(Pks_J) BARLEYcDNA 3613 374 Hordeum vulgare L. Manit LYM194 GeneArt 3614 3713 LYM196Topo B MAIZE Zea cDNA 3615 376 mays L. ND LYM197 pKS(Pks_J) MAIZE ZeacDNA 3616 3714 mays L. ND LYM198 pKS(Pks_J) MAIZE Zea cDNA 3617 378 maysL. ND LYM2 pKS(Pks_J) RICE Oryza cDNA 3482 241 sativa L. ND LYM20pKS(Pks_J) RICE Oryza cDNA 3498 257 sativa L. Japonica ND LYM200pKS(Pks_J) MAIZE Zea cDNA 3657 419 mays L. ND LYM201 pKS(Pks_J) MAIZEZea cDNA 3618 379 mays L. ND LYM203 pKS(Pks_J) MAIZE Zea cDNA 3619 380mays L. ND LYM204 Topo B MAIZE Zea cDNA 3620 381 mays L. Pioneer 30G54LYM206 pKS(Pks_J) MAIZE Zea cDNA 3621 3715 mays L. ND LYM207 Topo BMAIZE Zea cDNA 3622 3716 mays L. Pioneer 30G54 LYM208 pKS(Pks_J) MAIZEZea cDNA 3623 384 mays L. Pioneer 30G54 LYM21 pKS(Pks_J) RICE Oryza cDNA3499 258 sativa L. Japonica ND LYM212 pGXN MAIZE Zea cDNA 3624 3717(pKG + Nos + 35S) mays L. ND LYM213 pKS(Pks_J) MAIZE Zea cDNA 3625 386mays L. ND LYM215 pKS(Pks_J) MAIZE Zea cDNA 3626 3718 mays L. ND LYM217pGXN MAIZE Zea cDNA 3627 3719 mays L. ND LYM219 pKS(Pks_J) MAIZE ZeacDNA 3628 3720 mays L. Pioneer 30G54 LYM22 pGXN RICE Oryza cDNA 3500 259(pKG + Nos + 35S) sativa L. Japonica ND LYM220 pKS(Pks_J) MAIZE Zea cDNA3629 3721 mays L. Pioneer 30G54 LYM221 pKS(Pks_J) MAIZE Zea cDNA 36303722 mays L. Pioneer 30G54 LYM223 pGXNa MAIZE Zea cDNA 3631 392 mays L.Pioneer 30G54 LYM224 pKS(Pks_J) MAIZE Zea cDNA 3632 3723 mays L. Pioneer30G54 LYM227 GeneArt 3633 394 LYM228 Topo B MAIZE Zea cDNA 3634 3724mays L. Pioneer 30G54 LYM23 pKS(Pks_J) RICE Oryza cDNA 3501 260 sativaL. Japonica ND LYM232 Topo B RICE Oryza cDNA 3635 3725 sativa L.Japonica ND LYM233 GeneArt 3636 397 LYM234 GeneArt 3637 398 LYM236 pGXNRICE Oryza cDNA 3638 3726 (pKG + Nos + 35S) sativa L. Japonica ND LYM238Topo B RICE Oryza cDNA 3639 400 sativa L. Japonica ND LYM239 pKS(Pks_J)RICE Oryza cDNA 3640 3727 sativa L. Japonica ND LYM24 pGXN RICE OryzacDNA 3502 261 (pKG + Nos + 35S) sativa L. Japonica ND LYM240 pKS(Pks_J)RICE Oryza cDNA 3641 402 sativa L. Japonica ND LYM241 Topo B RICE OryzacDNA 3642 3728 sativa L. Japonica ND LYM242 pKS(Pks_J) RICE Oryza cDNA3643 404 sativa L. Indica ND LYM243 pKS(Pks_J) RICE Oryza cDNA 3644 405sativa L. Japonica ND LYM245 pKS(Pks_J) RICE Oryza cDNA 3645 406 sativaL. Japonica ND LYM248 pKS(Pks_J) RICE Oryza cDNA 3646 3729 sativa L.Indica ND LYM249 Topo B RICE Oryza cDNA 3647 3730 sativa L. JaponicaND + RICE Oryza sativa L. ND LYM250 pGXN RICE Oryza cDNA 3648 409 (pKG +Nos + 35S) sativa L. Japonica ND LYM251 Topo B RICE Oryza cDNA 3649 410sativa L. Japonica ND LYM252 pKS(Pks_J) RICE Oryza cDNA 3650 411 sativaL. Indica ND + RICE Oryza sativa L. Japonica ND LYM254 Topo B RICE OryzacDNA 3651 3731 sativa L. Japonica ND LYM255 pKS(Pks_J) RICE Oryza cDNA3652 3732 sativa L. Japonica ND LYM256 pKS(Pks_J) RICE Oryza cDNA 3656418 sativa L. Japonica ND LYM26 pGXN BARLEY cDNA 3503 262 (pKG + Nos +35S) Hordeum vulgare L. Manit LYM260 Topo B RICE Oryza cDNA 3653 414sativa L. Japonica ND LYM261 Topo B RICE Oryza cDNA 3654 415 sativa L.Japonica ND LYM267 pKS(Pks_J) MAIZE Zea cDNA 3658 420 mays L. ND LYM268Topo B RICE Oryza cDNA 3659 421 sativa L. Indica ND + RICE Oryza sativaL. Japonica ND LYM270 pKS(Pks_J) MAIZE Zea cDNA 3660 422 mays L. NDLYM271 pKS(Pks_J) MAIZE Zea cDNA 3661 423 mays L. Pioneer 30G54 LYM273_GpKS(Pks_J) RICE Oryza Genomic 3738 425 sativa L. Japonica ND LYM273_SGeneArt 3662 425 LYM274 pKS(Pks_J) RICE Oryza cDNA 3663 3734 sativa L.Japonica ND LYM277 Topo B RICE Oryza cDNA 3664 3735 sativa L. JaponicaND LYM278 pGXN BARLEY cDNA 3665 3736 (pKG + Nos + 35S) Hordeum vulgareL. Manit LYM283 Topo B RICE Oryza cDNA 3666 429 sativa L. ND LYM284pKS(Pks_J) RICE Oryza cDNA 3667 430 sativa L. Japonica ND LYM285pKS(Pks_J) RICE Oryza cDNA 3668 431 sativa L. Japonica ND LYM287pKS(Pks_J) RICE Oryza cDNA 3669 432 sativa L. Japonica ND LYM288 pGXNaRICE Oryza cDNA 3670 3737 sativa L. Indica ND + RICE Oryza sativa L.Japonica ND LYM289 pGXN BARLEY cDNA 3671 434 (pKG + Nos + 35S) Hordeumvulgare L. Manit LYM290 pKS(Pks_J) MAIZE Zea cDNA 3672 435 mays L. NDLYM291 pKS(Pks_J) RICE Oryza cDNA 3673 436 sativa L. Japonica ND LYM293pGXNa RICE Oryza cDNA 3674 437 sativa L. Indica ND LYM3 pKS(Pks_J) RICEOryza cDNA 3483 3675 sativa L. Indica ND LYM30 pGXNa RICE Oryza cDNA3504 3677 sativa L. ND LYM31 pGXNa RICE Oryza cDNA 3505 264 sativa L. NDLYM32 GeneArt 3506 265 LYM34 pKS(Pks_J) RICE Oryza cDNA 3507 3678 sativaL. Indica ND LYM35 pGXN RICE Oryza cDNA 3508 267 (pKG + Nos + 35S)sativa L. ND LYM36 GeneArt 3509 268 LYM37 pGXN RICE Oryza cDNA 3510 269(pKG + Nos + 35S) sativa L. Japonica ND LYM38 GeneArt 3511 270 LYM4pKS(Pks_J) RICE Oryza cDNA 3484 243 sativa L. ND LYM40 Topo B RICE OryzacDNA 3512 271 sativa L. Japonica ND LYM41 pGXN RICE Oryza cDNA 3513 272(pKG + Nos + 35S) sativa L. Japonica ND LYM42 pGXN RICE Oryza cDNA 3514273 (pKG + Nos + 35S) sativa L. Japonica ND LYM43 pGXN RICE Oryza cDNA3515 274 (pKG + Nos + 35S) sativa L. ND LYM44 pGXN RICE Oryza cDNA 3516275 (pKG + Nos + 35S) sativa L. Japonica ND LYM5 pKS(Pks_J) RICE OryzacDNA 3485 244 sativa L. Indica ND LYM51 pGXN BARLEY cDNA 3517 3679(pKG + Nos + 35S) Hordeum vulgare L. Manit LYM52 pKS(Pks_J) BARLEY cDNA3518 277 Hordeum vulgare L. Manit LYM53 pGXN MAIZE Zea cDNA 3519 3680(pKG + Nos + 35S) mays L. ND LYM56 pGXN BARLEY cDNA 3520 3681 (pKG +Nos + 35S) Hordeum vulgare L. Manit LYM57 pKS(Pks_J) RICE Oryza cDNA3521 3682 sativa L. Japonica ND LYM6 pKS(Pks_J) RICE Oryza cDNA 34863676 sativa L. ND LYM61 pKS(Pks_J) MAIZE Zea cDNA 3522 3683 mays L. NDLYM62 pKS(Pks_J) MAIZE Zea cDNA 3523 3684 mays L. ND LYM66 pKS(Pks_J)BARLEY cDNA 3524 3685 Hordeum vulgare L. Manit LYM67 pGXN RICE OryzacDNA 3525 284 (pKG + Nos + 35S) sativa L. ND LYM68 pGXNa RICE Oryza cDNA3526 3686 sativa L. ND LYM69 pGXN RICE Oryza cDNA 3527 286 (pKG + Nos +35S) sativa L. ND LYM7 pGXN RICE Oryza cDNA 3487 246 (pKG + Nos + 35S)sativa L. ND LYM73 Topo B RICE Oryza cDNA 3528 287 sativa L. ND LYM74GeneArt 3529 288 LYM79 pGXN MAIZE Zea cDNA 3530 3687 (pKG + Nos + 35S)mays L. ND LYM8 pKS(Pks_J) RICE Oryza cDNA 3488 247 sativa L. JaponicaND LYM82 pGXN BARLEY cDNA 3531 290 (pKG + Nos + 35S) Hordeum vulgare L.Manit LYM83 Topo B BARLEY cDNA 3532 3688 Hordeum vulgare L. Manit LYM84pKS(Pks_J) BARLEY cDNA 3533 292 Hordeum vulgare L. Manit LYM86pKS(Pks_J) RICE Oryza cDNA 3534 293 sativa L. Indica ND LYM88 pKS(Pks_J)ARABIDOPSIS cDNA 3535 294 Arabidopsis thaliana Transgenic Columbia LYM89pGXN ARABIDOPSIS cDNA 3536 295 (pKG + Nos + 35S) Arabidopsis thalianaTransgenic Columbia LYM9 pGXN RICE Oryza cDNA 3489 248 (pKG + Nos + 35S)sativa L. ND LYM90 pGXN BARLEY cDNA 3537 296 (pKG + Nos + 35S) Hordeumvulgare L. Manit LYM91 pGXN BARLEY cDNA 3538 297 (pKG + Nos + 35S)Hordeum vulgare L. Manit LYM93 Topo B BARLEY cDNA 3539 298 Hordeumvulgare L. Manit LYM95 pGXN BARLEY cDNA 3541 300 (pKG + Nos + 35S)Hordeum vulgare L. Manit LYM99 pKS(Pks_J) BARLEY cDNA 3540 299 Hordeumvulgare L. Manit Table 28: Cloned and synthetic genes are provided alongwith the sequence identifiers of their polynucleotides and polypeptides.Also provided are the source organism, tissue and the cloning vectors.ND = not a determined ecotype.

Selected DNA sequences were synthesized by a commercial supplierGeneArt, GmbH [Hypertext Transfer Protocol://World Wide Web (dot)geneart (dot) com/)]. Synthetic DNA is designed in silico. Suitablerestriction enzymes sites were added to the cloned sequences at the 5′end and at the 3′ end to enabled later cloning into the pQFN/pQYN_(—)6669 binary vectors downstream of the 6669 promoter (SEQ IDNO:4198).

Example 8 Transforming Agrobacterium Tumefaciens Cells with BinaryVectors Harboring Putative Genes

Each of the binary vectors described in Example 7 above are used totransform Agrobacterium cells. Two additional binary constructs, havinga GUS/Luciferase reporter gene replacing the selected gene (positioneddownstream of the At6669 promoter), are used as negative controls.

The binary vectors are introduced to Agrobacterium tumefaciens GV301, orLB4404 competent cells (about 10⁹ cells/mL) by electroporation. Theelectroporation is performed using a MicroPulser electroporator(Biorad), 0.2 cm cuvettes (Biorad) and EC-2 electroporation program(Biorad). The treated cells are cultured in LB liquid medium at 28° C.for 3 hours, then plated over LB agar supplemented with gentamycin (50mg/L; for Agrobacterium strains GV301) or streptomycin (300 mg/L; forAgrobacterium strain LB4404) and kanamycin (50 mg/L) at 28° C. for 48hours. Abrobacterium colonies which developed on the selective media areanalyzed by PCR using the primers which are designed to span theinserted sequence in the pPI plasmid. The resulting PCR products areisolated and sequenced as described in Example 3 above, to verify thatthe correct yield sequences are properly introduced to the Agrobacteriumcells.

Example 9 Producing Transgenic ArabidopsisPlants Expressing SelectedGenes According to Some Embodiments of the Invention

Materials and Experimental Methods

Plant transformation—The Arabidopsis thaliana var Columbia (T₀ plants)were transformed according to the Floral Dip procedure [Clough S J, BentA F. (1998) Floral dip: a simplified method for Agrobacterium-mediatedtransformation of Arabidopsis thaliana. Plant J. 16(6): 735-43; andDesfeux C, Clough S J, Bent A F. (2000) Female reproductive tissues arethe primary targets of Agrobacterium-mediated transformation by theArabidopsis floral-dip method. Plant Physiol. 123(3): 895-904] withminor modifications. Briefly, Arabidopsis thaliana Columbia (Co10) T₀plants were sown in 250 ml pots filled with wet peat-based growth mix.The pots were covered with aluminum foil and a plastic dome, kept at 4°C. for 3-4 days, then uncovered and incubated in a growth chamber at18-24° C. under 16/8 hours light/dark cycles. The T₀ plants were readyfor transformation six days before anthesis.

Single colonies of Agrobacterium carrying the binary vectors harboringthe yield genes were cultured in LB medium supplemented with kanamycin(50 mg/L) and gentamycin (50 mg/L). The cultures were incubated at 28°C. for 48 hours under vigorous shaking and centrifuged at 4000 rpm for 5minutes. The pellets comprising Agrobacterium cells were resuspended ina transformation medium which contained half-strength (2.15 g/L)Murashige-Skoog (Duchefa); 0.044 μM benzylamino purine (Sigma); 112 μg/LB5 Gambourg vitamins (Sigma); 5% sucrose; and 0.2 ml/L Silwet L-77 (OSISpecialists, CT) in double-distilled water, at pH of 5.7.

Transformation of T₀ plants was performed by inverting each plant intoan Agrobacterium suspension such that the above ground plant tissue wassubmerged for 3-5 seconds. Each inoculated T₀ plant was immediatelyplaced in a plastic tray, then covered with clear plastic dome tomaintain humidity and was kept in the dark at room temperature for 18hours to facilitate infection and transformation. Transformed(transgenic) plants were then uncovered and transferred to a greenhousefor recovery and maturation. The transgenic T₀ plants were grown in thegreenhouse for 3-5 weeks until siliques were brown and dry, then seedswere harvested from plants and kept at room temperature until sowing.

For generating T₁ and T₂ transgenic plants harboring the genes, seedscollected from transgenic T₀ plants were surface-sterilized by soakingin 70% ethanol for 1 minute, followed by soaking in 5% sodiumhypochlorite and 0.05% triton for 5 minutes. The surface-sterilizedseeds were thoroughly washed in sterile distilled water then placed onculture plates containing half-strength Murashig-Skoog (Duchefa); 2%sucrose; 0.8% plant agar; 50 mM kanamycin; and 200 mM carbenicylin(Duchefa). The culture plates were incubated at 4° C. for 48 hours thentransferred to a growth room at 25° C. for an additional week ofincubation. Vital T₁ Arabidopsis plants were transferred to a freshculture plates for another week of incubation. Following incubation theT₁ plants were removed from culture plates and planted in growth mixcontained in 250 ml pots. The transgenic plants were allowed to grow ina greenhouse to maturity. Seeds harvested from T₁ plants were culturedand grown to maturity as T₂ plants under the same conditions as used forculturing and growing the T₁ plants.

Example 10 Improved Transgenic Plant Performance—Greenhouse Assays

To analyze the effect of expression of the isolated polynucleotides inplants, plants performance was tested under greenhouse conditions.

Greenhouse assays—The plants were analyzed for their overall size,growth rate, flowering, seed yield, weight of 1,000 seeds, dry matterand harvest index (HI-seed yield/dry matter). Transgenic plantsperformance was compared to control plants grown in parallel under thesame conditions. Mock-transgenic plants expressing the uidA reportergene (GUS-Intron) or with no gene at all, under the same promoter wereused as control.

The experiment was planned in nested randomized plot distribution. Foreach gene of the invention three to five independent transformationevents were analyzed from each construct. In cases where a certain eventappears more than once, the event was tested in several independentexperiments.

Tables 29 and 31 specify the parameters measured in plants in thegreenhouse assays (till seed maturation and bolting assay,respectively).

Digital imaging—A laboratory image acquisition system, which consists ofa digital reflex camera (Canon EOS 300D) attached with a 55 mm focallength lens (Canon EF-S series), mounted on a reproduction device(Kaiser RS), which included 4 light units (4×150 Watts light bulb) isused for capturing images of plant samples.

The image capturing process was repeated every 2 days starting from day1 after transplanting till day 16. Same camera, placed in a custom madeiron mount, was used for capturing images of larger plants sawn in whitetubs in an environmental controlled greenhouse. The tubs were squareshape include 1.7 liter trays. During the capture process, the tubs wereplaced beneath the iron mount, while avoiding direct sun light andcasting of shadows.

An image analysis system was used, which consists of a personal desktopcomputer (Intel P4 3.0 GHz processor) and a public domain program—ImageJ1.39 (Java based image processing program which was developed at theU.S. National Institutes of Health and freely available on the internetat Hypertext Transfer Protocol://rsbweb (dot) nih (dot) gov/). Imageswere captured in resolution of 10 Mega Pixels (3888×2592 pixels) andstored in a low compression JPEG (Joint Photographic Experts Groupstandard) format. Next, analyzed data was saved to text files andprocessed using the JMP statistical analysis software (SAS institute).

Leaf growth analysis—Using the digital analysis leaves data wascalculated, including leaf number, rosette area, rosette diameter, leafblade area, plot coverage, leaf petiole length.

The Vegetative Growth Rate of the Plant was Defined by Formulas XIII,XIV, XV and XVI.Relative growth rate of leaf blade area=Regression coefficient of leafarea along time course.  Formula XIII:Relative growth rate of rosette area=Regression coefficient of rosettearea along time course.  Formula XIV:Relative growth rate of rosette diameter=Regression coefficient ofrosette diameter along time course.  Formula XVRelative growth rate of plot coverage=Regression coefficient of plotcoverage along time course.  Formula XVI

Seeds average weight (Seed weight or 1000 seed weight)—At the end of theexperiment all seeds were collected. The seeds were scattered on a glasstray and a picture was taken. Using the digital analysis, the number ofseeds in each sample was calculated.

Plant dry weight and seed yield—On about day 80 from sowing, the plantswere harvested and left to dry at 30° C. in a drying chamber. Thebiomass and seed weight of each plot were measured and divided by thenumber of plants in each plot. Dry weight=total weight of the vegetativeportion above ground (excluding roots) after drying at 30° C. in adrying chamber;

Seed yield per plant=total seed weight per plant (gr.).

1000 seed weight (the weight of 1000 seeds) (gr.).

The harvest index was calculated using Formula IV (Harvest Index=Averageseed yield per plant/Average dry weight) as described above.

Oil percentage in seeds—At the end of the experiment all seeds fromplots A-C were collected. Columbia seeds from 3 plots were mixedgrounded and then mounted onto the extraction chamber. 210 ml ofn-Hexane (Cat No. 080951 Biolab Ltd.) were used as the solvent. Theextraction was performed for 30 hours at medium heat 50° C. Once theextraction has ended the n-Hexane was evaporated using the evaporator at35° C. and vacuum conditions. The process was repeated twice. Theinformation gained from the Soxhlet extractor (Soxhlet, F. Diegewichtsanalytische Bestimmung des Milchfettes, Polytechnisches J.(Dingier's) 1879, 232, 461) was used to create a calibration curve forthe Low Resonance NMR. The content of oil of all seed samples wasdetermined using the Low Resonance NMR (MARAN Ultra— Oxford Instrument)and its MultiQuant sowftware package.

Oil yield—The oil yield was calculated using Formula IX (describedabove).

Silique length analysis—On day 50 from sowing, 30 siliques fromdifferent plants in each plot were sampled in block A. The chosensiliques were green-yellow in color and were collected from the bottomparts of a grown plant's stem. A digital photograph was taken todetermine silique's length.

Statistical analyses—To identify genes conferring significantly improvedtolerance to abiotic stresses, the results obtained from the transgenicplants were compared to those obtained from control plants. To identifyoutperforming genes and constructs, results from the independenttransformation events tested were analyzed separately. Data was analyzedusing Student's t-test and results were considered significant if the pvalue was less than 0.1. The JMP statistics software package was used(Version 5.2.1, SAS Institute Inc., Cary, N.C., USA).

Experimental Results

Plants expressing the polynucleotides of the some embodiments of theinvention were assayed for a number of commercially desired traits. Incases where a certain event appears more than once, the event was testedin several independent experiments.

TABLE 29 Measured parameters at the greenhouse till seed maturationassay (T2 experiment) for transformed agriculture improving trait genesTested Parameters Id Dry Weight (gr) A Harvest Index B Leaf Blade AreaTP4 (cm²) C Leaf Number TP4 D Leaf Petiole Length TP4 (cm) E PetioleRelative Area TP4 F Plot Coverage TP4 (cm²) G RGR Of Leaf Blade Area HRGR Of Plot Coverage I RGR Of Rosette Area J RGR Of Rosette Diameter KRosette Area TP4 (cm²) L Rosette Diameter TP4 (cm) M Seed Yield (gr) NSeeds Weight (gr) O Blade Relative Area TP4 P Oil Content Q RGR Of LeafNumber R Table 29: Provided are the identification (ID) letters of eachof the Tested Parameters. RGR—Relative Growth Rate; TP4—time point 4.

TABLE 30 Results obtained in a Greenhouse till seed maturation assay % %incr. incr. Gene P vs. Gene P vs. name Event ID Mean value cont. nameEvent ID Mean value cont. LYM16 11623.2 A 0.739 2.97E−02 10.4 LYM911633.7 P 93.115 4.23E−03 3.2 LYM57 12012.6 A 0.841 4.23E−02 25.7 LYM1511611.3 P 93.131 5.66E−03 3.2 LYM17 11681.4 A 0.728 5.16E−02 8.8 LYM411702.1 P 93.167 7.54E−03 3.2 LYM10 11744.1 A 0.723 8.27E−02 8 LYM1711682.3 P 92.747 8.70E−03 2.8 LYM95 12121.3 A 0.779 9.81E−02 16.5 LYM1711684.5 P 92.554 1.28E−02 2.6 CONTROL — A 0.669 — 0 LYM2 11691.2 P92.875 1.35E−02 2.9 LYM16 11623.5 B 0.543 6.50E−05 45.1 LYM7 11594.3 P92.513 1.79E−02 2.5 LYM24 12063.3 B 0.515 2.78E−04 37.6 LYM67 11782.5 P94.037 1.83E−02 4.2 LYM10 11741.4 B 0.499 3.74E−04 33.4 LYM44 11884.3 P92.306 2.09E−02 2.3 LYM7 11594.2 B 0.498 1.10E−03 33.1 LYM62 12022.4 P92.296 2.21E−02 2.3 LYM44 11885.3 B 0.473 1.50E−03 26.6 LYM19 11751.4 P92.244 2.38E−02 2.2 LYM15 11611.3 B 0.477 3.91E−03 27.7 LYM17 11684.4 P92.438 3.04E−02 2.4 LYM2 11695.1 B 0.457 4.23E−03 22.2 LYM31 11923.1 P92.399 3.32E−02 2.4 LYM30 11913.3 B 0.462 4.25E−03 23.6 LYM34 11903.3 P92.07 3.49E−02 2 LYM8 11984.1 B 0.472 4.44E−03 26.3 LYM12 11871.3 P91.999 3.94E−02 2 LYM31 11923.1 B 0.471 4.64E−03 26 LYM15 11614.3 P91.996 5.05E−02 1.9 LYM14 12051.1 B 0.454 5.37E−03 21.5 LYM15 11614.4 P91.877 5.09E−02 1.8 LYM2 11692.3 B 0.546 5.62E−03 46 LYM10 11741.4 P91.979 5.99E−02 1.9 LYM16 11624.6 B 0.468 8.76E−03 25.1 LYM57 12012.4 P91.752 6.64E−02 1.7 LYM66 11954.4 B 0.455 9.16E−03 21.7 LYM24 12063.3 P92.883 6.73E−02 2.9 LYM34 11904.3 B 0.442 1.11E−02 18.3 LYM16 11624.6 P91.723 7.65E−02 1.6 LYM53 11843.2 B 0.506 1.24E−02 35.4 LYM26 11824.3 P91.672 7.95E−02 1.6 LYM35 11812.4 B 0.446 1.49E−02 19.2 LYM66 11955.2 P91.693 8.09E−02 1.6 LYM4 11706.5 B 0.456 1.57E−02 21.9 LYM62 12023.7 P92.17 8.37E−02 2.1 LYM15 11612.2 B 0.437 1.59E−02 16.9 LYM30 11913.3 P91.637 8.66E−02 1.5 LYM19 11754.1 B 0.448 1.60E−02 19.8 LYM12 11873.4 P91.84 9.17E−02 1.8 LYM9 11634.6 B 0.466 1.61E−02 24.6 LYM51 11891.1 P92.63 9.56E−02 2.6 LYM1 11601.1 B 0.465 1.63E−02 24.3 CONTROL — P 90.239— 0 LYM57 12013.1 B 0.429 3.09E−02 14.8 LYM17 11684.5 Q 31.925 1.22E−0413.3 LYM17 11684.5 B 0.501 3.38E−02 34.1 LYM66 11952.1 Q 31.76 1.43E−0412.7 LYM30 11912.6 B 0.506 3.67E−02 35.3 LYM34 11904.3 Q 31.585 2.06E−0412.1 LYM24 12061.2 B 0.481 4.69E−02 28.5 LYM17 11682.3 Q 32.16 2.39E−0414.1 LYM82 12203.2 B 0.53 4.78E−02 41.7 LYM82 12203.2 Q 31.185 4.56E−0410.7 LYM31 11924.4 B 0.437 4.78E−02 16.7 LYM2 11692.3 Q 31.17 7.38E−0410.6 LYM6 11735.1 B 0.42 5.60E−02 12.3 LYM14 12051.1 Q 30.425 2.85E−03 8LYM8 11983.1 B 0.47 6.47E−02 25.8 LYM43 11791.2 Q 31.015 3.17E−03 10.1LYM6 11734.3 B 0.418 6.56E−02 11.9 LYM43 11793.2 Q 31.92 4.77E−03 13.3LYM30 11912.7 B 0.512 6.75E−02 36.9 LYM26 11824.3 Q 30.13 5.77E−03 6.9LYM26 11824.3 B 0.483 6.80E−02 29.2 LYM51 11893.4 Q 30.12 7.02E−03 6.9LYM8 11982.4 B 0.475 7.82E−02 27.1 LYM10 11741.4 Q 30.01 8.17E−03 6.5LYM12 11871.1 B 0.457 8.07E−02 22.2 LYM22 11761.3 Q 30.895 8.20E−03 9.6LYM67 11782.6 B 0.49 8.15E−02 31.1 LYM15 11611.3 Q 30.05 8.49E−03 6.6LYM22 11764.1 B 0.474 8.22E−02 26.8 LYM24 12063.3 Q 30.215 1.03E−02 7.2LYM51 11893.4 B 0.476 8.62E−02 27.4 LYM43 11792.2 Q 29.985 1.19E−02 6.4LYM21 11674.5 B 0.516 8.83E−02 38 LYM62 12023.2 Q 29.855 1.23E−02 5.9LYM7 11594.3 B 0.464 8.85E−02 24 LYM7 11591.5 Q 29.845 1.27E−02 5.9LYM24 12064.1 B 0.491 8.92E−02 31.2 LYM66 11955.2 Q 30.365 1.58E−02 7.7LYM2 11691.2 B 0.454 9.14E−02 21.4 LYM24 12061.2 Q 29.76 1.61E−02 5.6LYM13 11772.2 B 0.474 9.21E−02 26.9 LYM69 11852.2 Q 29.82 1.91E−02 5.8LYM68 11942.3 B 0.426 9.22E−02 13.9 LYM62 12023.7 Q 29.69 2.03E−02 5.3LYM44 11884.3 B 0.414 9.80E−02 10.6 LYM17 11684.4 Q 29.68 2.16E−02 5.3CONTROL — B 0.374 — 0 LYM7 11592.1 Q 31.66 3.45E−02 12.3 LYM95 12121.3 C0.73 2.06E−04 46.2 LYM31 11923.1 Q 29.53 3.69E−02 4.8 LYM10 11741.2 C0.655 3.02E−03 31.2 LYM53 11841.2 Q 30.06 3.89E−02 6.7 LYM21 11671.2 C0.619 4.67E−03 23.9 LYM57 12012.6 Q 29.38 4.78E−02 4.2 LYM62 12024.2 C0.626 7.02E−03 25.3 LYM66 11954.4 Q 31.52 5.68E−02 11.8 LYM66 11953.1 C0.602 1.02E−02 20.5 LYM14 12052.4 Q 29.42 5.94E−02 4.4 LYM10 11744.1 C0.602 1.02E−02 20.5 LYM51 11894.2 Q 30.185 6.04E−02 7.1 LYM4 11706.5 C0.575 3.74E−02 15.2 LYM68 11941.3 Q 30.515 6.20E−02 8.3 LYM44 11882.1 C0.569 5.06E−02 13.9 LYM8 11984.1 Q 29.395 6.25E−02 4.3 LYM66 11955.2 C0.586 5.09E−02 17.4 LYM30 11912.6 Q 31.815 6.57E−02 12.9 LYM82 12201.1 C0.567 6.28E−02 13.6 LYM13 11772.1 Q 29.53 8.65E−02 4.8 LYM68 11941.4 C0.564 6.49E−02 13.1 LYM24 12064.1 Q 30.505 9.05E−02 8.2 LYM95 12121.2 C0.557 9.41E−02 11.6 LYM44 11885.4 Q 29.57 9.26E−02 4.9 CONTROL — C 0.499— 0 LYM1 11601.1 Q 29.685 9.43E−02 5.3 LYM31 11923.1 D 9.125 4.78E−048.8 CONTROL — Q 28.183 — 0 LYM26 11824.6 D 8.938 4.23E−03 6.5 LYM17512651.6 A 1.514 2.92E−03 50.2 LYM4 11705.2 D 8.938 4.23E−03 6.5 LYM25613321.2 A 1.169 5.61E−02 16 LYM9 11632.1 D 8.938 4.23E−03 6.5 LYM14712581.4 A 1.154 6.79E−02 14.5 LYM44 11882.1 D 8.875 4.88E−03 5.8 CONTROL— A 1.008 — 0 LYM8 11984.1 D 8.875 4.88E−03 5.8 LYM207 13251.4 B 0.3567.41E−02 8.2 LYM4 11702.1 D 9.5 5.72E−03 13.3 LYM73 12624.1 B 0.3629.94E−02 9.9 LYM10 11744.5 D 8.813 1.53E−02 5.1 CONTROL — B 0.329 — 0LYM24 12061.1 D 8.813 1.53E−02 5.1 LYM206 12601.3 C 0.313 3.92E−03 31.8LYM66 11952.1 D 8.75 1.97E−02 4.3 LYM207 13251.4 C 0.281 2.47E−02 18.2LYM69 11851.2 D 8.75 1.97E−02 4.3 LYM241 13271.2 C 0.291 3.27E−02 22.5LYM95 12121.3 D 8.75 1.97E−02 4.3 LYM159 13354.5 C 0.272 4.39E−02 14.8LYM53 11842.4 D 9 3.32E−02 7.3 LYM91 13283.1 C 0.268 7.20E−02 13 LYM1611623.2 D 8.875 6.05E−02 5.8 CONTROL — C 0.237 — 0 LYM37 11803.2 D 8.8756.05E−02 5.8 LYM175 12653.3 D 9 1.81E−02 3 LYM57 12012.6 D 8.8756.05E−02 5.8 LYM206 12603.1 D 9 1.81E−02 3 LYM15 11614.4 D 8.6886.06E−02 3.6 LYM147 12581.4 D 9.25 7.10E−02 5.9 LYM43 11791.5 D 8.6886.06E−02 3.6 LYM147 12584.4 D 9.25 7.10E−02 5.9 LYM44 11885.3 D 8.6258.97E−02 2.8 CONTROL — D 8.734 — 0 LYM53 11844.2 D 8.625 8.97E−02 2.8LYM207 13251.4 E 0.494 2.25E−03 29 LYM7 11594.3 D 8.625 8.97E−02 2.8LYM206 12601.3 E 0.49 3.51E−03 27.9 CONTROL — D 8.388 — 0 LYM91 13283.1E 0.451 2.44E−02 17.8 LYM95 12121.3 E 0.871 6.40E−05 20.5 CONTROL — E0.383 — 0 LYM10 11741.2 E 0.854 1.68E−04 18 LYM175 12651.6 F 8.4579.98E−03 14.9 LYM51 11893.4 E 0.814 1.64E−03 12.5 LYM241 13271.2 F 7.9998.84E−02 8.7 LYM26 11824.1 E 0.864 3.71E−03 19.4 CONTROL — F 7.36 — 0LYM16 11623.2 E 0.793 8.69E−03 9.6 LYM241 13271.2 G 13.924 3.22E−02 20.3LYM12 11871.1 E 0.79 8.71E−03 9.2 LYM256 13322.3 G 13.012 5.32E−02 12.5LYM41 11834.3 E 0.788 9.62E−03 9 LYM91 13283.1 G 12.996 5.81E−02 12.3LYM44 11885.4 E 0.791 2.21E−02 9.3 CONTROL — G 11.57 — 0 LYM17 11681.4 E0.788 2.38E−02 8.9 LYM206 12601.3 H 0.038 9.68E−03 39.1 LYM21 11673.1 E0.822 2.48E−02 13.7 LYM206 12602.1 H 0.037 3.48E−02 35.7 LYM20 11711.1 E0.786 4.67E−02 8.7 LYM147 12584.4 H 0.036 4.44E−02 30.6 LYM4 11706.5 E0.818 5.29E−02 13.1 LYM147 12583.3 H 0.035 4.93E−02 29.1 LYM68 11942.3 E0.786 6.52E−02 8.7 LYM203 12664.1 H 0.035 7.71E−02 27.4 LYM53 11841.1 E0.823 9.25E−02 13.8 LYM159 13354.6 H 0.035 8.34E−02 28.1 CONTROL — E0.723 — 0 LYM241 13271.2 H 0.034 9.00E−02 24.6 LYM34 11902.2 F 13.3635.21E−03 33.8 CONTROL — H 0.027 — 0 LYM17 11681.4 F 11.764 3.07E−02 17.8LYM206 12601.3 I 1.904 2.91E−02 34.1 LYM37 11802.2 F 11.839 5.95E−0218.5 LYM147 12583.3 I 1.834 5.96E−02 29.1 CONTROL — F 9.989 — 0 LYM14712584.4 I 1.823 6.86E−02 28.3 LYM21 11671.2 G 29.318 2.73E−03 29 CONTROL— I 1.421 — 0 LYM95 12121.3 G 35.398 5.12E−03 55.7 LYM206 12601.3 J0.238 2.91E−02 34.1 LYM44 11882.1 G 28.419 6.04E−03 25 LYM147 12583.3 J0.229 5.96E−02 29.1 LYM10 11741.2 G 31.636 7.14E−03 39.1 LYM147 12584.4J 0.228 6.86E−02 28.3 LYM66 11953.1 G 28.02 8.78E−03 23.2 CONTROL — J0.178 — 0 LYM4 11706.5 G 28.515 1.11E−02 25.4 LYM206 12601.3 K 0.2273.54E−02 26.3 LYM62 12024.2 G 30.017 1.16E−02 32 LYM203 12664.1 K 0.2256.18E−02 25.1 LYM66 11955.2 G 27.277 1.76E−02 20 LYM159 13354.6 K 0.228.46E−02 22.6 LYM68 11941.4 G 26.646 3.40E−02 17.2 LYM206 12602.1 K0.223 8.54E−02 24 LYM82 12201.1 G 26.548 4.02E−02 16.8 LYM241 13271.2 K0.217 9.49E−02 21.1 LYM9 11632.1 G 26.845 4.65E−02 18.1 CONTROL — K0.179 — 0 LYM53 11841.1 G 28.482 7.52E−02 25.3 LYM241 13271.2 L 1.743.22E−02 20.3 LYM95 12121.2 G 26.986 9.98E−02 18.7 LYM256 13322.3 L1.627 5.32E−02 12.5 CONTROL — G 22.735 — 0 LYM91 13283.1 L 1.6255.81E−02 12.3 LYM95 12121.3 H 0.094 1.34E−02 47.3 CONTROL — L 1.446 — 0LYM10 11741.2 H 0.084 7.76E−02 31.9 LYM206 12601.3 M 2.453 2.09E−03 18CONTROL — H 0.064 — 0 LYM241 13271.2 M 2.397 1.28E−02 15.3 LYM95 12121.3I 4.691 6.13E−03 54.8 LYM207 13251.4 M 2.296 3.04E−02 10.4 LYM10 11741.2I 4.228 3.51E−02 39.5 LYM147 12584.4 M 2.386 8.91E−02 14.8 LYM62 12024.2I 3.957 8.88E−02 30.6 LYM256 13322.3 M 2.239 9.17E−02 7.7 LYM10 11744.5I 3.988 9.32E−02 31.6 CONTROL — M 2.079 — 0 CONTROL — I 3.03 — 0 LYM23612594.3 O 0.026 6.00E−02 15.3 LYM95 12121.3 J 0.586 8.07E−03 52.2 LYM14712584.4 O 0.028 6.46E−02 22.5 LYM10 11741.2 J 0.529 4.45E−02 37.2CONTROL — O 0.023 — 0 CONTROL — J 0.385 — 0 LYM157 13341.3 P 93.9773.21E−02 2.1 LYM95 12121.3 K 0.411 5.44E−03 28.5 LYM256 13324.2 P 93.9543.46E−02 2.1 LYM10 11741.2 K 0.392 2.01E−02 22.4 LYM159 13354.5 P 93.9837.24E−02 2.1 LYM10 11744.5 K 0.383 4.42E−02 19.7 LYM223 12671.2 P 93.5878.19E−02 1.7 LYM10 11744.1 K 0.378 5.54E−02 18.2 LYM157 13341.7 P 93.6169.88E−02 1.7 LYM26 11824.1 K 0.377 6.36E−02 17.6 CONTROL — P 92.018 — 0LYM21 11671.2 K 0.377 6.69E−02 17.8 LYM250 12613.4 Q 30.535 3.32E−03 7.9LYM68 11941.4 K 0.373 7.72E−02 16.6 LYM206 12601.2 Q 29.685 1.79E−02 4.9CONTROL — K 0.32 — 0 LYM147 12582.3 Q 29.84 3.32E−02 5.5 LYM21 11671.2 L3.665 3.75E−03 26.8 LYM203 12662.3 Q 31.715 3.46E−02 12.1 LYM95 12121.3L 4.425 5.70E−03 53.1 LYM157 13341.3 Q 29.42 4.35E−02 4 LYM10 11741.2 L3.954 8.47E−03 36.9 LYM206 12603.2 Q 29.34 6.50E−02 3.7 LYM44 11882.1 L3.552 8.51E−03 22.9 LYM91 13283.1 Q 29.245 7.37E−02 3.3 LYM66 11953.1 L3.502 1.25E−02 21.2 CONTROL — Q 28.298 — 0 LYM10 11744.1 L 3.4981.28E−02 21.1 LYM206 12603.1 R 0.682 1.24E−02 27.2 LYM62 12024.2 L 3.7521.43E−02 29.9 CONTROL — R 0.536 — 0 LYM4 11706.5 L 3.564 1.51E−02 23.4LYM113 12443.1 B 0.532 9.57E−03 25.9 LYM66 11955.2 L 3.41 2.53E−02 18LYM267 13604.5 B 0.48 2.91E−02 13.6 LYM68 11941.4 L 3.331 4.96E−02 15.3LYM285 12734.7 B 0.477 3.69E−02 12.8 LYM82 12201.1 L 3.319 5.85E−02 14.8LYM113 12444.4 B 0.464 9.15E−02 9.7 LYM9 11632.1 L 3.356 6.43E−02 16.1CONTROL — B 0.423 — 0 LYM53 11841.1 L 3.56 8.80E−02 23.2 CONTROL — E0.515 — 0 CONTROL — L 2.889 — 0 LYM255 13081.5 F 8.406 9.80E−05 18.5LYM95 12121.3 M 3.993 1.50E−05 26.6 LYM116 13204.6 F 7.893 5.11E−04 11.2LYM10 11741.2 M 3.71 3.24E−04 17.6 LYM287 12771.6 F 7.885 5.55E−04 11.1LYM62 12024.2 M 3.594 1.18E−03 14 LYM284 12884.6 F 7.834 7.75E−04 10.4LYM10 11744.1 M 3.58 1.97E−03 13.5 LYM239 13041.7 F 7.666 3.45E−03 8LYM82 12201.1 M 3.499 8.49E−03 10.9 LYM113 12444.5 F 8.133 6.77E−03 14.6LYM44 11885.4 M 3.407 2.47E−02 8 LYM287 12771.7 F 7.628 7.48E−03 7.5LYM9 11632.1 M 3.475 2.70E−02 10.2 LYM110 12923.5 F 8.115 1.19E−02 14.4LYM20 11711.1 M 3.387 2.94E−02 7.4 LYM52 12895.7 F 7.749 1.33E−02 9.2LYM66 11953.1 M 3.494 3.07E−02 10.8 LYM238 12764.8 F 8.587 4.56E−02 21LYM21 11673.1 M 3.421 3.23E−02 8.5 LYM112 13374.4 F 7.715 6.97E−02 8.7LYM51 11893.4 M 3.481 3.65E−02 10.4 LYM56 13112.5 F 7.798 9.00E−02 9.9LYM43 11792.2 M 3.43 5.63E−02 8.7 CONTROL — F 7.096 — 0 LYM26 11824.1 M3.537 6.22E−02 12.1 LYM56 13111.7 N 0.554 7.80E−02 10.8 LYM17 11682.3 M3.353 6.60E−02 6.3 CONTROL — N 0.5 — 0 LYM16 11623.2 M 3.512 6.70E−0211.3 LYM255 13082.9 O 0.025 3.34E−02 7.8 LYM66 11955.2 M 3.419 8.25E−028.4 LYM141 12402.4 O 0.027 3.92E−02 19.5 LYM17 11681.4 M 3.326 8.35E−025.5 LYM113 12442.1 O 0.025 4.02E−02 7.8 LYM41 11834.3 M 3.318 9.59E−025.2 CONTROL — O 0.023 — 0 LYM21 11671.2 M 3.649 9.83E−02 15.7 LYM18113572.2 P 95.247 4.17E−02 1.9 CONTROL — M 3.154 — 0 LYM239 13044.9 P95.317 9.21E−02 2 LYM66 11954.4 N 0.311 2.80E−03 25.1 LYM232 13023.6 P93.976 9.43E−02 0.6 LYM31 11923.1 N 0.302 5.66E−03 21.3 LYM156 12963.5 P94.452 9.56E−02 1.1 LYM8 11982.4 N 0.301 5.78E−03 21.2 CONTROL — P93.441 — 0 LYM17 11683.1 N 0.296 1.02E−02 18.9 LYM255 13082.9 Q 34.4159.06E−03 8.2 LYM7 11594.3 N 0.284 4.39E−02 14 LYM112 13372.3 Q 34.231.03E−02 7.6 LYM57 12012.6 N 0.285 5.22E−02 14.6 LYM196 13613.1 Q 33.7353.50E−02 6.1 LYM17 11684.5 N 0.277 8.28E−02 11.1 LYM121 13211.8 Q 33.467.26E−02 5.2 LYM13 11772.2 N 0.311 9.17E−02 25.1 LYM287 12771.7 Q 33.237.99E−02 4.5 CONTROL — N 0.249 — 0 LYM56 13111.7 Q 33.21 8.34E−02 4.4LYM12 11872.1 O 0.024 1.60E−05 19.6 LYM156 12963.3 Q 33.4 9.09E−02 5LYM22 11762.1 O 0.022 4.50E−05 13.3 LYM238 12761.6 Q 34.2 9.81E−02 7.5LYM43 11792.2 O 0.026 4.80E−05 33.1 CONTROL — Q 31.809 — 0 LYM31 11923.4O 0.022 1.05E−04 12.1 LYM43 11791.2 O 0.022 1.77E−04 11.2 LYM53 11841.1O 0.022 3.43E−04 10 LYM95 12121.3 O 0.026 3.71E−04 33.1 LYM95 12121.2 O0.023 3.96E−04 14.5 LYM10 11744.1 O 0.023 2.55E−03 15.8 LYM4 11702.1 O0.021 3.43E−03 8.2 LYM82 12204.6 O 0.021 4.85E−03 6.4 LYM82 12204.2 O0.021 6.10E−03 6.4 LYM34 11904.3 O 0.021 6.18E−03 6.7 LYM14 12054.2 O0.021 1.02E−02 5.5 LYM66 11954.4 O 0.023 3.15E−02 14.6 LYM6 11734.3 O0.024 6.98E−02 22.1 LYM16 11623.2 O 0.023 7.55E−02 15.8 LYM82 12201.1 O0.024 9.20E−02 21.9 CONTROL — O 0.02 — 0 Table 30. Results of thegreenhouse experiments. Provided are the measured values of each testedparameter [parameters (ID.) A-P according to the parameters described inTable 29 above] in plants expressing the indicated polynucleotides. “Ev”= event; “P” = P-value; “Mean” = the average of measured parameteracross replicates. % incr. vs. cont. = percentage of increase versuscontrol (as compared to control).

TABLE 31 Measured parameters at the greenhouse till bolting assay (T2experiment) for transformed agriculture improving trait genes TestedParameters ID Blade Relative Area TP4 A Dry Weight (gr) B Fresh Weight(gr) C Leaf Blade Area TP4 (cm²) D Leaf Number TP4 E Leaf Petiole LengthTP4 (cm) F Petiole Relative Area TP4 G Plot Coverage TP4 (cm²) H RGR OfLeaf Blade Area J RGR Of Leaf Number K RGR Of Plot Coverage L RGR OfRosette Area M RGR Of Rosette Diameter N Rosette Area TP4 (cm²) ORosette Diameter TP4 (cm) P Table 31: Provided are the identification(ID) letters of each of the Tested Parameters. TP4—time Point 4;RGR—Relative Growth Rate.

TABLE 32 Results obtained in a T2 experiment at the bolting assay % %incr. incr. Gene P vs. Gene P vs. name Event ID Mean value cont. nameEvent ID Mean value cont. LYM14 12052.5 A 92.405 3.09E−03 2.5 LYM3111923.4 F 0.489 1.69E−04 26.4 LYM62 12022.4 A 92.349 4.28E−03 2.5 LYM11613202.12 F 0.479 5.48E−04 23.8 LYM20 11712.2 A 92.893 5.39E−03 3.1LYM238 12764.8 F 0.459 1.64E−03 18.6 LYM24 12064.1 A 92.339 6.75E−03 2.5LYM20 11711.2 F 0.458 1.80E−03 18.5 LYM57 12012.2 A 92.251 6.81E−03 2.4LYM67 11782.6 F 0.455 2.14E−03 17.7 LYM2 11695.1 A 92.121 7.11E−03 2.2LYM88 12193.1 F 0.494 2.43E−03 27.7 LYM15 11612.2 A 94.348 1.01E−02 4.7LYM99 12244.2 F 0.45 3.75E−03 16.4 LYM21 11672.4 A 92.404 1.14E−02 2.5LYM239 13044.8 F 0.441 9.74E−03 13.9 LYM19 11751.4 A 91.836 1.32E−02 1.9LYM24 12061.4 F 0.435 1.27E−02 12.5 LYM53 11844.2 A 91.822 1.53E−02 1.9LYM53 11841.1 F 0.434 1.43E−02 12.2 LYM12 11871.1 A 92.949 1.90E−02 3.2LYM82 12201.1 F 0.454 1.47E−02 17.4 LYM17 11683.1 A 92.267 2.24E−02 2.4LYM26 11824.1 F 0.46 3.65E−02 18.9 LYM57 12012.4 A 91.637 2.27E−02 1.7LYM30 11912.6 F 0.433 4.15E−02 12 LYM51 11891.1 A 91.813 2.38E−02 1.9LYM26 11824.3 F 0.436 4.37E−02 12.7 LYM41 11832.2 A 91.578 2.83E−02 1.6LYM285 12733.9 F 0.518 4.87E−02 34 LYM19 11753.1 A 91.958 3.26E−02 2.1LYM62 12023.2 F 0.445 6.80E−02 15.1 LYM51 11893.4 A 91.504 3.29E−02 1.5LYM99 12243.2 F 0.418 7.28E−02 7.9 LYM35 11812.3 A 91.489 3.40E−02 1.5LYM128 12641.5 F 0.546 8.57E−02 41 LYM2 11695.3 A 91.533 5.57E−02 1.6LYM95 12121.2 F 0.512 1.12E−01 32.3 LYM34 11903.2 A 91.766 6.00E−02 1.8LYM66 11953.6 F 0.427 1.18E−01 10.3 LYM37 11802.2 A 92.49 7.93E−02 2.6LYM239 13042.9 F 0.431 1.30E−01 11.4 LYM10 11742.2 A 91.536 7.98E−02 1.6LYM12 11872.1 F 0.548 1.47E−01 41.7 LYM31 11923.4 A 91.474 8.92E−02 1.5LYM128 12641.3 F 0.409 1.66E−01 5.8 LYM30 11912.7 A 91.122 9.52E−02 1.1LYM99 12243.1 F 0.554 1.68E−01 43.1 LYM9 11632.1 A 91.352 1.07E−01 1.4LYM66 11954.4 F 0.483 1.83E−01 24.8 LYM26 11824.6 A 91.076 1.19E−01 1.1LYM232 13024.6 F 0.42 1.96E−01 8.6 LYM57 12012.6 A 91.044 1.24E−01 1LYM26 11824.6 F 0.429 2.22E−01 10.8 LYM16 11623.2 A 92.118 1.47E−01 2.2LYM43 11791.4 F 0.41 2.43E−01 5.9 LYM69 11854.2 A 92.115 1.61E−01 2.2LYM12 11873.4 F 0.462 2.56E−01 19.5 LYM57 12013.1 A 91.886 1.66E−01 2LYM103 12713.5 F 0.444 3.55E−01 14.8 LYM15 11613.3 A 91.904 1.68E−01 2LYM53 11842.4 F 0.411 3.55E−01 6.3 LYM20 11711.3 A 91.669 1.89E−01 1.7LYM285 12734.9 F 0.456 4.57E−01 18 LYM41 11833.1 A 91.384 1.92E−01 1.4LYM12 11871.1 F 0.448 4.60E−01 15.7 LYM67 11783.5 A 91.023 1.94E−01 1LYM128 12641.1 F 0.407 5.45E−01 5.2 LYM22 11764.1 A 90.853 2.00E−01 0.8LYM30 11913.4 F 0.397 5.70E−01 2.6 LYM69 11851.2 A 91.74 2.05E−01 1.8LYM69 11852.2 F 0.411 5.90E−01 6.2 LYM66 11953.1 A 92.257 2.06E−01 2.4LYM95 12124.4 F 0.425 6.13E−01 9.9 LYM26 11822.5 A 91.028 2.12E−01 1LYM43 11793.2 F 0.421 6.52E−01 8.9 LYM30 11912.6 A 90.841 2.14E−01 0.8LYM14 12051.4 F 0.408 6.57E−01 5.6 LYM31 11924.4 A 91.921 2.30E−01 2LYM232 13024.7 F 0.435 6.69E−01 12.5 LYM4 11701.1 A 91.754 2.39E−01 1.8LYM24 12064.1 F 0.416 7.26E−01 7.6 LYM14 12051.4 A 90.83 2.43E−01 0.8LYM67 11782.4 F 0.416 7.28E−01 7.6 LYM67 11782.6 A 91.469 2.52E−01 1.5LYM30 11913.5 F 0.403 7.37E−01 4.3 LYM62 12023.2 A 91.752 2.52E−01 1.8LYM43 11791.5 F 0.397 7.38E−01 2.6 LYM57 12013.5 A 91.699 2.60E−01 1.8LYM145 12951.9 F 0.394 7.61E−01 1.9 LYM68 11942.2 A 90.959 2.62E−01 0.9LYM30 11912.7 F 0.4 7.69E−01 3.4 LYM19 11752.2 A 91.08 2.63E−01 1.1LYM31 11924.4 F 0.407 7.75E−01 5.2 LYM44 11884.1 A 91.109 2.88E−01 1.1LYM99 12244.1 F 0.402 7.94E−01 3.8 LYM53 11841.1 A 92.28 2.88E−01 2.4LYM26 11824.5 F 0.406 8.37E−01 5 LYM69 11852.2 A 91.959 2.91E−01 2.1LYM20 11716.5 F 0.395 8.66E−01 2.1 LYM31 11923.1 A 90.876 2.91E−01 0.9LYM66 11955.2 F 0.392 8.71E−01 1.4 LYM66 11955.2 A 92.703 2.94E−01 2.9LYM53 11843.2 F 0.394 8.94E−01 1.8 LYM1 11603.2 A 92.051 3.02E−01 2.2LYM232 13024.4 F 0.397 9.29E−01 2.6 LYM41 11831.5 A 91.826 3.07E−01 1.9LYM156 12963.1 F 0.389 9.65E−01 0.6 LYM20 11711.2 A 90.881 3.47E−01 0.9LYM88 12194.2 F 0.387 9.95E−01 0.1 LYM13 11771.6 A 90.65 3.62E−01 0.6CONTROL — F 0.387 — 0 LYM67 11781.5 A 90.995 3.69E−01 1 LYM88 12193.1 G8.066 2.50E−05 25.2 LYM2 11691.2 A 91.385 3.77E−01 1.4 LYM232 13024.4 G7.589 2.58E−04 17.8 LYM30 11913.4 A 90.853 3.81E−01 0.8 LYM99 12244.2 G7.549 3.29E−04 17.2 LYM1 11601.1 A 90.859 3.94E−01 0.8 LYM88 12191.2 G7.736 2.37E−03 20.1 LYM10 11741.2 A 91.019 3.97E−01 1 LYM62 12023.2 G7.932 2.88E−03 23.1 LYM24 12061.1 A 91.643 3.97E−01 1.7 LYM30 11912.6 G7.215 4.09E−03 12 LYM13 11772.1 A 91.742 4.02E−01 1.8 LYM128 12641.5 G7.228 5.32E−03 12.2 LYM14 12051.1 A 90.781 4.03E−01 0.7 LYM116 13204.4 G7.075 8.47E−03 9.8 LYM4 11705.2 A 92.132 4.20E−01 2.2 LYM82 12201.1 G7.084 8.81E−03 9.9 LYM17 11682.1 A 92.467 4.22E−01 2.6 LYM69 11852.2 G7.055 9.96E−03 9.5 LYM1 11604.4 A 91.803 4.50E−01 1.9 LYM66 11953.1 G7.118 1.07E−02 10.5 LYM8 11982.4 A 91.723 4.54E−01 1.8 LYM53 11844.2 G7.005 1.48E−02 8.7 LYM34 11902.2 A 91.334 4.56E−01 1.4 LYM57 12012.6 G7.014 1.54E−02 8.9 LYM43 11793.2 A 91.534 4.59E−01 1.6 LYM238 12764.8 G7.251 2.21E−02 12.5 LYM51 11894.2 A 91.583 4.61E−01 1.6 LYM31 11921.3 G6.955 2.21E−02 7.9 LYM21 11674.5 A 90.703 4.62E−01 0.7 LYM30 11913.5 G7.742 2.81E−02 20.2 LYM69 11853.4 A 91.048 5.05E−01 1 LYM43 11791.5 G7.093 2.87E−02 10.1 LYM12 11874.1 A 90.863 5.30E−01 0.8 LYM53 11842.4 G7.517 3.17E−02 16.7 LYM44 11885.3 A 91.411 5.42E−01 1.4 LYM99 12244.1 G6.952 3.21E−02 7.9 LYM12 11872.1 A 91.494 5.47E−01 1.5 LYM156 12963.1 G6.886 3.95E−02 6.9 LYM9 11633.7 A 90.819 5.50E−01 0.8 LYM41 11831.1 G 74.82E−02 8.6 LYM13 11772.2 A 91.548 5.65E−01 1.6 LYM31 11923.4 G 7.5514.93E−02 17.2 LYM34 11903.3 A 91.319 5.74E−01 1.3 LYM271 12724.9 G 6.8645.02E−02 6.5 LYM67 11782.5 A 90.978 5.82E−01 1 LYM95 12124.4 G 6.8735.19E−02 6.7 LYM51 11893.2 A 90.82 5.94E−01 0.8 LYM82 12204.2 G 7.0521.10E−01 9.4 LYM15 11611.3 A 90.387 6.12E−01 0.3 LYM125 12932.6 G 6.7521.22E−01 4.8 LYM12 11874.3 A 90.471 6.22E−01 0.4 LYM12 11872.1 G 7.4991.25E−01 16.4 LYM13 11771.9 A 90.421 6.27E−01 0.3 LYM121 13214.5 G 6.7371.37E−01 4.6 LYM62 12022.2 A 90.902 6.52E−01 0.9 LYM239 13042.9 G 6.751.43E−01 4.8 LYM41 11834.2 A 90.979 6.83E−01 1 LYM66 11954.4 G 6.9021.52E−01 7.1 LYM19 11751.5 A 91.121 6.90E−01 1.1 LYM51 11894.2 G 7.541.56E−01 17 LYM35 11813.5 A 90.606 7.22E−01 0.6 LYM285 12734.9 G 8.1791.81E−01 26.9 LYM22 11762.2 A 90.475 7.23E−01 0.4 LYM128 12641.4 G 6.7021.87E−01 4 LYM16 11622.4 A 90.591 7.35E−01 0.5 LYM57 12012.4 G 6.7251.88E−01 4.4 LYM67 11783.4 A 90.578 7.36E−01 0.5 LYM14 12052.5 G 7.4721.90E−01 16 LYM17 11684.4 A 90.539 7.37E−01 0.5 LYM239 13044.8 G 7.0871.96E−01 10 LYM41 11831.1 A 90.519 7.60E−01 0.5 LYM43 11791.4 G 8.5672.01E−01 33 LYM9 11633.2 A 90.343 7.61E−01 0.3 LYM121 13212.6 G 7.7462.15E−01 20.2 LYM14 12052.4 A 90.586 7.64E−01 0.5 LYM99 12243.1 G 7.9352.19E−01 23.1 LYM43 11792.2 A 90.67 7.75E−01 0.6 LYM62 12022.4 G 7.2092.28E−01 11.9 LYM66 11953.6 A 90.649 7.76E−01 0.6 LYM56 13112.6 G 7.5672.56E−01 17.4 LYM20 11716.5 A 90.596 7.79E−01 0.5 LYM14 12054.2 G 7.7472.74E−01 20.2 LYM37 11803.1 A 90.346 8.10E−01 0.3 LYM69 11853.4 G 7.2013.46E−01 11.8 LYM30 11913.5 A 90.539 8.10E−01 0.5 LYM12 11873.4 G 8.0163.55E−01 24.4 LYM21 11673.1 A 90.585 8.23E−01 0.5 LYM51 11891.1 G 7.3863.60E−01 14.6 LYM17 11684.5 A 90.747 8.33E−01 0.7 LYM95 12121.2 G 6.9123.61E−01 7.3 LYM34 11904.3 A 90.407 8.52E−01 0.3 LYM145 12952.9 G 7.173.74E−01 11.3 LYM24 12063.3 A 90.682 8.56E−01 0.6 LYM284 12884.7 G 6.913.81E−01 7.2 LYM2 11692.3 A 90.203 8.71E−01 0.1 LYM53 11841.2 G 7.393.85E−01 14.7 LYM24 12062.3 A 90.6 8.81E−01 0.5 LYM238 12762.8 G 7.0753.94E−01 9.8 LYM22 11762.1 A 90.201 8.83E−01 0.1 LYM62 12022.1 G 7.5253.95E−01 16.8 LYM37 11803.2 A 90.244 9.04E−01 0.2 LYM43 11791.2 G 7.7034.20E−01 19.5 LYM62 12022.1 A 90.233 9.15E−01 0.1 LYM51 11893.4 G 7.2724.52E−01 12.9 LYM51 11892.1 A 90.154 9.39E−01 0.1 LYM156 12961.9 G 6.6774.65E−01 3.6 LYM10 11744.1 A 90.187 9.50E−01 0.1 LYM31 11922.3 G 6.6614.71E−01 3.4 LYM68 11941.4 A 90.163 9.56E−01 0.1 LYM43 11793.2 G 7.3934.87E−01 14.7 LYM17 11683.3 A 90.195 9.65E−01 0.1 LYM232 13024.6 G 6.5964.89E−01 2.4 LYM9 11632.2 A 90.128 9.71E−01 0 LYM232 13024.5 G 6.7324.92E−01 4.5 LYM19 11754.1 A 90.118 9.95E−01 0 LYM145 12954.7 G 6.584.97E−01 2.1 CONTROL — A 90.108 — 0 LYM41 11833.1 G 6.865 5.04E−01 6.5LYM14 12051.4 B 0.211 5.89E−03 26.4 LYM128 12641.1 G 6.796 5.07E−01 5.5LYM10 11744.1 B 0.2 1.92E−02 20 LYM14 12051.1 G 6.808 5.14E−01 5.7 LYM3411902.2 B 0.192 6.57E−02 15.1 LYM53 11841.1 G 6.947 5.15E−01 7.8 LYM911632.1 B 0.191 7.00E−02 14.4 LYM88 12194.2 G 6.864 5.26E−01 6.5 LYM211695.1 B 0.188 1.04E−01 12.5 LYM24 12061.4 G 6.842 5.31E−01 6.2 LYM5712013.1 B 0.188 1.04E−01 12.5 LYM62 12023.4 G 7.308 5.31E−01 13.4 LYM6611954.4 B 0.191 1.36E−01 14.4 LYM51 11893.2 G 6.689 5.34E−01 3.8 LYM5712012.4 B 0.191 1.42E−01 14.7 LYM57 12012.2 G 6.686 5.42E−01 3.8 LYM6611953.6 B 0.186 1.65E−01 11.7 LYM30 11912.7 G 6.949 5.55E−01 7.8 LYM3711803.1 B 0.183 1.75E−01 10.1 LYM66 11953.6 G 6.632 5.60E−01 2.9 LYM5311844.2 B 0.184 1.80E−01 10.2 LYM53 11843.2 G 6.959 5.75E−01 8 LYM911632.2 B 0.186 1.90E−01 11.4 LYM56 13111.7 G 7.268 5.80E−01 12.8 LYM3511812.3 B 0.189 2.46E−01 13.2 LYM67 11783.5 G 6.724 5.88E−01 4.4 LYM411701.1 B 0.184 2.47E−01 10.2 LYM95 12124.5 G 6.849 6.12E−01 6.3 LYM3111924.4 B 0.181 2.72E−01 8.4 LYM31 11924.4 G 6.597 6.17E−01 2.4 LYM3511813.5 B 0.219 2.93E−01 31.2 LYM41 11832.2 G 6.533 6.27E−01 1.4 LYM5712012.6 B 0.187 2.98E−01 12.1 LYM51 11892.1 G 6.978 6.31E−01 8.3 LYM111604.4 B 0.184 3.17E−01 10.6 LYM43 11792.2 G 6.782 6.47E−01 5.2 LYM1412051.1 B 0.18 3.27E−01 8 LYM285 12734.7 G 7.284 6.55E−01 13 LYM3011912.6 B 0.191 3.85E−01 14.3 LYM271 12721.8 G 6.637 6.59E−01 3 LYM1311771.6 B 0.208 4.16E−01 24.9 LYM30 11913.4 G 7.07 6.73E−01 9.7 LYM1311771.9 B 0.192 4.37E−01 15.1 LYM31 11923.1 G 6.854 6.88E−01 6.4 LYM3111923.1 B 0.176 4.57E−01 5.4 LYM82 12203.2 G 6.635 7.11E−01 3 LYM6711783.5 B 0.178 4.69E−01 6.9 LYM20 11716.3 G 6.74 7.14E−01 4.6 LYM1011741.2 B 0.177 5.16E−01 6.1 LYM239 13041.7 G 6.709 7.58E−01 4.1 LYM2111673.1 B 0.176 5.27E−01 5.7 LYM24 12064.1 G 6.573 7.64E−01 2 LYM6911851.2 B 0.178 5.36E−01 6.5 LYM239 13044.7 G 6.629 7.70E−01 2.9 LYM6911852.2 B 0.179 5.45E−01 7.6 LYM88 12193.5 G 6.595 7.72E−01 2.4 LYM111603.2 B 0.173 6.15E−01 3.5 LYM20 11712.2 G 6.616 7.87E−01 2.7 LYM711594.2 B 0.184 6.18E−01 10.2 LYM62 12022.2 G 6.612 7.91E−01 2.6 LYM3411903.2 B 0.188 6.33E−01 12.9 LYM67 11782.6 G 6.509 7.99E−01 1 LYM2111674.5 B 0.172 6.73E−01 3.1 LYM20 11716.5 G 6.541 8.15E−01 1.5 LYM6811942.3 B 0.176 6.91E−01 5.7 LYM232 13024.7 G 6.663 8.27E−01 3.4 LYM1412054.2 B 0.176 7.18E−01 5.4 LYM26 11824.1 G 6.558 8.57E−01 1.8 LYM3011913.4 B 0.176 7.18E−01 5.4 LYM99 12243.2 G 6.512 8.64E−01 1.1 LYM5111893.2 B 0.171 7.40E−01 2.4 LYM121 13211.8 G 6.511 8.82E−01 1 LYM5311842.4 B 0.182 7.45E−01 9.1 LYM99 12241.1 G 6.503 8.85E−01 0.9 LYM4411884.3 B 0.171 8.45E−01 2.4 LYM14 12051.4 G 6.468 8.96E−01 0.4 LYM1711683.3 B 0.169 8.75E−01 1.2 LYM67 11782.4 G 6.536 9.09E−01 1.4 LYM1511611.3 B 0.168 9.01E−01 0.9 LYM26 11824.5 G 6.469 9.55E−01 0.4 LYM811982.7 B 0.169 9.10E−01 1.2 LYM26 11824.3 G 6.475 9.58E−01 0.5 LYM1211872.1 B 0.169 9.21E−01 1.6 LYM95 12121.4 G 6.458 9.88E−01 0.2 LYM5111893.4 B 0.169 9.25E−01 1.6 LYM24 12062.3 G 6.457 9.90E−01 0.2 LYM3411903.3 B 0.168 9.59E−01 0.5 LYM239 13041.1 G 6.448 9.93E−01 0.1 LYM711592.1 B 0.168 9.67E−01 0.5 LYM12 11871.1 G 6.445 9.94E−01 0 CONTROL —B 0.167 — 0 CONTROL — G 6.444 — 0 LYM10 11744.1 C 2.881 4.60E−03 21LYM116 13202.12 H 18.312 4.00E−06 47.5 LYM35 11813.5 C 2.85 6.51E−0319.7 LYM88 12193.1 H 15.681 1.86E−04 26.3 LYM9 11632.1 C 2.85 6.67E−0319.7 LYM31 11923.4 H 14.837 1.11E−03 19.5 LYM57 12013.1 C 2.738 2.45E−0215 LYM20 11711.2 H 17.126 1.79E−03 38 LYM9 11633.7 C 2.713 3.07E−02 13.9LYM53 11841.1 H 15.641 2.39E−03 26 LYM35 11812.3 C 2.681 6.94E−02 12.6LYM67 11782.6 H 16.773 4.00E−03 35.1 LYM66 11953.6 C 2.606 1.11E−01 9.5LYM82 12201.1 H 14.907 1.38E−02 20.1 LYM14 12051.4 C 2.788 2.12E−01 17.1LYM12 11871.3 H 14.033 1.64E−02 13.1 LYM57 12012.4 C 2.55 2.56E−01 7.1LYM26 11824.3 H 15.354 2.22E−02 23.7 LYM13 11771.9 C 2.694 2.59E−01 13.2LYM238 12764.8 H 15.539 2.58E−02 25.2 LYM1 11603.2 C 2.55 2.80E−01 7.1LYM88 12194.2 H 13.639 3.29E−02 9.9 LYM66 11954.4 C 2.525 3.28E−01 6.1LYM99 12244.2 H 14.055 4.42E−02 13.2 LYM68 11942.2 C 2.494 4.00E−01 4.8LYM53 11843.2 H 13.752 6.09E−02 10.8 LYM30 11912.6 C 2.662 4.05E−01 11.8LYM128 12641.5 H 19.01 6.58E−02 53.2 LYM57 12012.6 C 2.813 4.19E−01 18.1LYM99 12243.1 H 18.3 8.16E−02 47.4 LYM34 11902.2 C 2.681 4.48E−01 12.6LYM26 11824.1 H 16.706 8.96E−02 34.6 LYM51 11893.4 C 2.556 4.54E−01 7.4LYM128 12641.3 H 16.77 9.41E−02 35.1 LYM2 11695.1 C 2.538 5.35E−01 6.6LYM239 13042.9 H 15.316 1.28E−01 23.4 LYM69 11851.2 C 2.65 5.41E−01 11.3LYM26 11824.6 H 15.643 1.64E−01 26 LYM13 11771.6 C 2.525 5.65E−01 6.1LYM285 12733.9 H 18.928 1.66E−01 52.5 LYM53 11844.2 C 2.619 5.75E−01 10LYM20 11716.5 H 13.667 1.68E−01 10.1 LYM16 11623.2 C 2.456 6.08E−01 3.2LYM24 12061.4 H 15.875 1.72E−01 27.9 LYM24 12061.2 C 2.45 6.15E−01 2.9LYM30 11912.7 H 13.113 1.73E−01 5.7 LYM1 11604.4 C 2.506 6.22E−01 5.3LYM116 13202.7 H 14.52 1.78E−01 17 LYM14 12051.1 C 2.475 6.44E−01 4LYM103 12713.5 H 16.234 1.81E−01 30.8 LYM31 11924.4 C 2.456 6.45E−01 3.2LYM66 11954.4 H 16.504 1.98E−01 33 LYM7 11594.2 C 2.519 6.45E−01 5.8LYM66 11953.6 H 13.082 2.10E−01 5.4 LYM34 11903.2 C 2.525 6.69E−01 6.1LYM12 11872.1 H 19.153 2.18E−01 54.3 LYM67 11783.5 C 2.563 7.21E−01 7.6LYM95 12124.4 H 14.508 2.21E−01 16.9 LYM68 11942.3 C 2.569 7.32E−01 7.9LYM66 11955.2 H 14.124 2.35E−01 13.8 LYM53 11842.4 C 2.581 7.49E−01 8.4LYM31 11924.4 H 14.278 2.42E−01 15 LYM17 11683.3 C 2.406 8.49E−01 1.1LYM95 12121.2 H 17.135 3.06E−01 38.1 LYM30 11913.4 C 2.456 8.69E−01 3.2LYM69 11852.2 H 14.517 3.11E−01 17 LYM69 11852.2 C 2.425 8.75E−01 1.9LYM14 12051.4 H 14.254 3.15E−01 14.8 LYM51 11891.1 C 2.438 8.88E−01 2.4LYM12 11871.1 H 16.236 3.18E−01 30.8 LYM44 11884.3 C 2.413 9.00E−01 1.3LYM43 11791.4 H 13.352 3.60E−01 7.6 LYM1 11602.6 C 2.388 9.61E−01 0.3LYM103 12712.8 H 14.075 4.03E−01 13.4 LYM8 11982.7 C 2.394 9.68E−01 0.6LYM239 13044.8 H 13.881 4.35E−01 11.8 LYM14 12054.2 C 2.388 9.72E−01 0.3LYM62 12023.2 H 13.479 4.46E−01 8.6 LYM10 11741.2 C 2.388 9.76E−01 0.3LYM232 13024.6 H 13.49 4.54E−01 8.7 LYM9 11632.2 C 2.381 9.97E−01 0LYM67 11782.4 H 14.203 4.80E−01 14.4 CONTROL — C 2.381 — 0 LYM30 11912.6H 13.885 4.95E−01 11.9 LYM9 11632.1 D 0.63 7.73E−04 26.2 LYM156 12963.1H 13.692 5.55E−01 10.3 LYM57 12013.1 D 0.604 2.91E−03 21.1 LYM23213024.7 H 15.409 5.68E−01 24.1 LYM30 11912.6 D 0.59 6.70E−03 18.3 LYM4311791.5 H 12.738 5.74E−01 2.6 LYM35 11812.3 D 0.574 1.51E−02 15.1 LYM9912243.2 H 13.041 5.75E−01 5.1 LYM9 11633.7 D 0.564 7.87E−02 13 LYM12812641.1 H 13.474 6.12E−01 8.6 LYM10 11744.1 D 0.58 9.91E−02 16.2 LYM1211873.4 H 12.838 6.27E−01 3.4 LYM10 11741.2 D 0.544 9.99E−02 9.1 LYM2611824.5 H 14.928 6.29E−01 20.3 LYM57 12012.4 D 0.541 1.20E−01 8.5 LYM10312711.8 H 12.75 6.58E−01 2.7 LYM31 11924.4 D 0.567 1.79E−01 13.5 LYM2412064.1 H 13.685 6.61E−01 10.3 LYM1 11602.6 D 0.541 1.97E−01 8.5 LYM2611821.2 H 13.651 6.78E−01 10 LYM1 11603.2 D 0.581 2.09E−01 16.4 LYM11613204.4 H 14.229 7.49E−01 14.6 LYM51 11891.1 D 0.543 2.39E−01 8.7 LYM4311793.2 H 13.044 8.21E−01 5.1 LYM13 11771.9 D 0.538 2.66E−01 7.8 LYM14512951.9 H 12.489 8.72E−01 0.6 LYM53 11842.4 D 0.586 3.05E−01 17.5 LYM3011913.5 H 12.846 8.73E−01 3.5 LYM35 11813.5 D 0.558 3.13E−01 11.8 LYM3011913.4 H 12.658 8.85E−01 2 LYM13 11771.6 D 0.524 3.24E−01 5 LYM6212023.5 H 12.488 8.95E−01 0.6 LYM14 12051.4 D 0.565 3.33E−01 13.3 LYM28512734.9 H 12.563 9.45E−01 1.2 LYM69 11852.2 D 0.533 3.41E−01 6.8 LYM10312712.5 H 12.458 9.73E−01 0.4 LYM66 11953.6 D 0.536 3.86E−01 7.4 CONTROL— H 12.412 — 0 LYM57 12012.6 D 0.601 3.94E−01 20.5 LYM12 11872.1 J 0.051.96E−04 59.7 LYM1 11604.4 D 0.591 4.48E−01 18.5 LYM116 13202.12 J 0.0463.31E−04 47.1 LYM14 12051.1 D 0.54 4.53E−01 8.3 LYM20 11711.2 J 0.0456.36E−04 44.3 LYM34 11902.2 D 0.562 4.60E−01 12.6 LYM128 12641.5 J 0.0447.56E−04 40.5 LYM2 11695.1 D 0.542 4.83E−01 8.6 LYM285 12733.9 J 0.0451.31E−03 43.5 LYM31 11923.4 D 0.546 5.90E−01 9.3 LYM238 12764.8 J 0.0424.59E−03 34.9 LYM69 11851.2 D 0.516 6.13E−01 3.3 LYM26 11824.1 J 0.0427.07E−03 33.7 LYM12 11872.1 D 0.53 6.82E−01 6.2 LYM239 13042.9 J 0.0418.56E−03 31.8 LYM7 11594.2 D 0.53 6.83E−01 6.2 LYM103 12713.5 J 0.0429.55E−03 34 LYM21 11674.5 D 0.51 6.94E−01 2.3 LYM99 12243.1 J 0.0391.57E−02 26.4 LYM68 11942.3 D 0.538 7.30E−01 7.7 LYM12 11871.1 J 0.0411.61E−02 31 LYM53 11844.2 D 0.508 7.44E−01 1.7 LYM67 11782.6 J 0.041.77E−02 28.2 LYM35 11811.3 D 0.529 7.70E−01 6.1 LYM116 13202.7 J 0.042.12E−02 28.6 LYM24 12061.2 D 0.508 7.91E−01 1.9 LYM24 12061.4 J 0.042.32E−02 28.1 LYM51 11893.4 D 0.513 8.07E−01 2.9 LYM26 11824.6 J 0.0392.72E−02 25.9 LYM34 11903.2 D 0.535 8.16E−01 7.1 LYM128 12641.3 J 0.0393.65E−02 25.4 LYM1 11601.1 D 0.515 8.25E−01 3.2 LYM26 11824.3 J 0.0394.30E−02 23.4 LYM30 11913.4 D 0.507 9.38E−01 1.6 LYM66 11954.4 J 0.0384.56E−02 22.5 LYM43 11791.4 D 0.5 9.64E−01 0.2 LYM103 12712.8 J 0.0385.16E−02 22.9 CONTROL — D 0.499 — 0 LYM95 12121.2 J 0.039 5.69E−02 23.8LYM35 11811.3 E 10 1.23E−02 7.1 LYM24 12064.1 J 0.039 6.86E−02 23.9LYM10 11744.1 E 10.313 2.53E−02 10.4 LYM232 13024.7 J 0.04 8.05E−02 28.4LYM30 11912.6 E 9.857 8.06E−02 5.6 LYM232 13024.6 J 0.038 8.34E−02 20.4LYM34 11902.2 E 9.75 1.25E−01 4.4 LYM14 12051.4 J 0.037 9.99E−02 19.7LYM69 11851.2 E 9.688 1.30E−01 3.8 LYM12 11871.3 J 0.037 1.14E−01 18.1LYM69 11852.2 E 10.188 1.53E−01 9.1 LYM30 11912.6 J 0.037 1.23E−01 18.6LYM9 11632.1 E 10.125 2.33E−01 8.4 LYM239 13044.8 J 0.037 1.34E−01 17.6LYM1 11604.4 E 9.625 2.62E−01 3.1 LYM31 11924.4 J 0.036 1.64E−01 15.9LYM13 11772.1 E 9.563 3.10E−01 2.4 LYM156 12963.1 J 0.036 1.70E−01 15.9LYM12 11872.1 E 9.5 4.38E−01 1.7 LYM238 12763.7 J 0.036 1.78E−01 14.5LYM26 11824.6 E 9.625 4.45E−01 3.1 LYM53 11841.1 J 0.036 1.78E−01 14.9LYM13 11771.9 E 9.688 4.47E−01 3.8 LYM116 13204.4 J 0.038 1.81E−01 22.8LYM14 12051.4 E 9.75 4.53E−01 4.4 LYM20 11716.5 J 0.036 1.95E−01 14.5LYM37 11801.1 E 9.563 4.57E−01 2.4 LYM26 11821.2 J 0.036 2.34E−01 14.6LYM9 11633.7 E 9.563 4.57E−01 2.4 LYM26 11824.5 J 0.037 2.36E−01 17.1LYM35 11812.3 E 9.813 4.59E−01 5.1 LYM128 12641.1 J 0.035 3.24E−01 11.7LYM14 12054.2 E 9.5 5.11E−01 1.7 LYM31 11923.4 J 0.035 3.32E−01 10.6LYM53 11842.4 E 9.813 5.48E−01 5.1 LYM53 11843.2 J 0.034 3.70E−01 9.8LYM21 11674.5 E 9.75 6.27E−01 4.4 LYM69 11852.2 J 0.034 3.93E−01 9.1LYM1 11601.1 E 9.438 6.42E−01 1.1 LYM67 11782.4 J 0.034 4.05E−01 9 LYM1412051.1 E 9.438 6.42E−01 1.1 LYM103 12712.5 J 0.034 4.13E−01 9.1 LYM1511611.3 E 9.438 6.42E−01 1.1 LYM30 11913.5 J 0.034 4.32E−01 9.6 LYM5311844.2 E 9.438 6.42E−01 1.1 LYM88 12193.1 J 0.034 4.41E−01 8.1 LYM3511811.2 E 9.5 6.51E−01 1.7 LYM103 12711.8 J 0.034 4.68E−01 7.8 LYM3711803.2 E 9.5 6.51E−01 1.7 LYM99 12244.2 J 0.034 4.71E−01 7.7 LYM3011913.4 E 9.75 6.79E−01 4.4 LYM95 12124.4 J 0.034 4.71E−01 7.6 LYM3411903.2 E 9.438 7.32E−01 1.1 LYM31 11921.3 J 0.033 5.04E−01 7.3 LYM1911751.4 E 9.5 7.45E−01 1.7 LYM66 11955.2 J 0.033 5.27E−01 6.6 LYM111602.6 E 9.375 8.76E−01 0.4 LYM30 11912.7 J 0.033 5.60E−01 6.4 LYM5712012.6 E 9.438 8.89E−01 1.1 LYM62 12023.2 J 0.033 5.61E−01 6.2 LYM5111891.1 E 9.375 9.39E−01 0.4 LYM20 11716.3 J 0.033 5.84E−01 6.4 CONTROL— E 9.337 — 0 LYM30 11913.4 J 0.033 6.20E−01 5.8 LYM57 12012.4 F 0.8067.51E−02 8.8 LYM238 12762.8 J 0.033 6.21E−01 5.6 LYM35 11811.3 F 0.832.97E−01 12.1 LYM238 12763.5 J 0.033 6.27E−01 5.3 LYM53 11842.4 F 0.7873.26E−01 6.2 LYM156 12961.9 J 0.033 6.33E−01 5.1 LYM14 12051.4 F 0.8463.32E−01 14.3 LYM57 12012.2 J 0.033 6.41E−01 5.1 LYM35 11813.5 F 0.7773.52E−01 4.9 LYM145 12951.9 J 0.033 6.87E−01 4.4 LYM68 11942.3 F 0.7863.74E−01 6.2 LYM12 11873.4 J 0.032 7.45E−01 3.6 LYM30 11912.6 F 0.8054.37E−01 8.6 LYM20 11712.2 J 0.032 7.62E−01 3.5 LYM51 11891.1 F 0.7644.68E−01 3.1 LYM41 11831.5 J 0.032 7.96E−01 2.8 LYM9 11632.1 F 0.7695.87E−01 3.8 LYM103 12714.6 J 0.032 8.74E−01 1.9 LYM9 11633.7 F 0.765.93E−01 2.6 LYM285 12734.9 J 0.032 8.76E−01 1.8 LYM13 11771.6 F 0.7616.04E−01 2.7 LYM239 13044.7 J 0.032 9.02E−01 1.4 LYM13 11771.9 F 0.766.32E−01 2.7 LYM82 12201.1 J 0.032 9.28E−01 0.9 LYM37 11801.1 F 0.7586.33E−01 2.3 LYM66 11953.6 J 0.031 9.36E−01 0.8 LYM7 11594.2 F 0.7596.93E−01 2.5 LYM238 12761.6 J 0.031 9.94E−01 0.1 LYM57 12012.6 F 0.7617.81E−01 2.8 LYM24 12062.3 J 0.031 9.97E−01 0 LYM57 12013.1 F 0.7598.06E−01 2.5 CONTROL — J 0.031 — 0 LYM35 11811.2 F 0.75 8.65E−01 1.2LYM26 11824.3 K 0.686 7.37E−03 43.8 LYM14 12051.1 F 0.748 8.75E−01 0.9LYM69 11852.2 K 0.659 2.22E−02 38.2 LYM10 11744.1 F 0.747 8.99E−01 0.9LYM128 12641.1 K 0.641 3.49E−02 34.5 LYM34 11903.2 F 0.757 9.24E−01 2.2LYM95 12121.2 K 0.641 3.71E−02 34.4 LYM1 11604.4 F 0.745 9.30E−01 0.5LYM24 12061.4 K 0.633 4.62E−02 32.8 CONTROL — F 0.741 — 0 LYM14 12051.4K 0.627 5.47E−02 31.5 LYM37 11801.1 G 11.978 9.54E−04 26.2 LYM12812642.1 K 0.635 5.90E−02 33.2 LYM19 11754.1 G 10.53 1.26E−01 11 LYM12812641.5 K 0.623 7.60E−02 30.6 LYM35 11813.5 G 10.283 1.29E−01 8.4 LYM11613202.12 K 0.603 8.80E−02 26.5 LYM9 11633.2 G 10.294 1.30E−01 8.5 LYM23812764.8 K 0.608 8.89E−02 27.5 LYM68 11942.3 G 10.196 1.75E−01 7.4 LYM3011912.6 K 0.605 9.08E−02 26.8 LYM4 11706.5 G 10.33 2.38E−01 8.8 LYM27713103.1 K 0.602 9.87E−02 26.1 LYM35 11811.3 G 10.931 2.53E−01 15.2 LYM2611824.1 K 0.595 1.15E−01 24.7 LYM19 11752.2 G 10.007 3.09E−01 5.5 LYM28512733.9 K 0.597 1.19E−01 25.2 LYM22 11761.3 G 10.119 3.11E−01 6.6 LYM4311791.4 K 0.596 1.21E−01 25 LYM37 11801.2 G 10.859 3.30E−01 14.4 LYM6212023.5 K 0.593 1.29E−01 24.3 LYM43 11791.4 G 10.473 3.51E−01 10.4 LYM1211873.4 K 0.592 1.35E−01 24.2 LYM43 11791.5 G 10.532 3.81E−01 11 LYM11613204.4 K 0.607 1.36E−01 27.4 LYM7 11594.2 G 10.052 4.96E−01 5.9 LYM3011913.4 K 0.593 1.53E−01 24.3 LYM20 11716.5 G 10.104 5.90E−01 6.5 LYM12113212.6 K 0.584 1.56E−01 22.4 LYM8 11983.1 G 9.748 5.93E−01 2.7 LYM28512734.7 K 0.6 1.70E−01 25.9 LYM7 11591.2 G 9.771 6.16E−01 3 LYM5311842.4 K 0.581 1.70E−01 21.9 LYM67 11781.5 G 9.718 6.39E−01 2.4 LYM9512124.4 K 0.574 1.84E−01 20.4 LYM62 12023.4 G 9.723 6.48E−01 2.5 LYM2011711.2 K 0.581 1.90E−01 21.7 LYM16 11624.4 G 9.761 6.89E−01 2.9 LYM12812641.3 K 0.569 2.06E−01 19.3 LYM9 11634.5 G 9.753 7.05E−01 2.8 LYM6212023.2 K 0.577 2.14E−01 21 LYM53 11842.4 G 9.673 7.13E−01 1.9 LYM14512953.5 K 0.571 2.18E−01 19.7 LYM12 11874.1 G 9.655 7.33E−01 1.7 LYM5311841.2 K 0.568 2.21E−01 19 LYM37 11803.2 G 9.663 7.61E−01 1.8 LYM28512734.9 K 0.576 2.21E−01 20.8 LYM43 11791.2 G 9.676 8.13E−01 2 LYM23213024.4 K 0.578 2.36E−01 21.2 LYM35 11811.2 G 9.598 8.21E−01 1.1 LYM10312712.5 K 0.571 2.39E−01 19.7 LYM62 12023.7 G 9.592 8.31E−01 1.1 LYM23213024.6 K 0.566 2.45E−01 18.6 LYM68 11943.2 G 9.652 8.34E−01 1.7 LYM5311841.1 K 0.568 2.50E−01 19.2 LYM15 11612.3 G 9.59 8.47E−01 1.1 LYM9912243.1 K 0.576 2.57E−01 20.8 LYM19 11753.4 G 9.661 8.70E−01 1.8 LYM2412064.1 K 0.568 2.60E−01 19 LYM67 11782.5 G 9.594 9.27E−01 1.1 LYM11012923.8 K 0.559 2.60E−01 17.2 LYM2 11693.3 G 9.593 9.33E−01 1.1 LYM6611954.4 K 0.565 2.60E−01 18.4 LYM43 11793.2 G 9.569 9.71E−01 0.8 LYM10312713.5 K 0.565 2.61E−01 18.6 LYM44 11882.1 G 9.529 9.82E−01 0.4 LYM1211871.1 K 0.57 2.69E−01 19.5 LYM14 12051.4 G 9.501 9.83E−01 0.1 LYM9912241.1 K 0.558 2.70E−01 17.1 LYM13 11773.2 G 9.501 9.83E−01 0.1 LYM8212201.1 K 0.56 2.74E−01 17.5 LYM15 11614.4 G 9.493 9.97E−01 0 LYM3111923.4 K 0.564 2.76E−01 18.2 CONTROL — G 9.49 — 0 LYM99 12243.2 K 0.5592.99E−01 17.2 LYM9 11632.1 H 33.914 2.21E−04 36.9 LYM145 12954.8 K 0.5543.06E−01 16.1 LYM57 12013.1 H 29.579 9.76E−03 19.4 LYM66 11955.2 K 0.5573.10E−01 16.7 LYM35 11812.3 H 29.204 1.31E−02 17.9 LYM284 12884.6 K0.554 3.10E−01 16.1 LYM57 12012.4 H 27.626 1.08E−01 11.5 LYM232 13024.7K 0.554 3.11E−01 16.1 LYM10 11744.1 H 31.643 1.14E−01 27.7 LYM23913044.8 K 0.555 3.13E−01 16.4 LYM35 11813.5 H 27.993 1.18E−01 13 LYM4311793.2 K 0.563 3.17E−01 18.1 LYM10 11741.2 H 26.964 1.50E−01 8.8 LYM1412051.1 K 0.553 3.22E−01 15.9 LYM69 11852.2 H 27.516 1.79E−01 11 LYM11613202.7 K 0.552 3.34E−01 15.7 LYM9 11633.7 H 27.959 1.85E−01 12.8 LYM9512124.5 K 0.548 3.45E−01 14.9 LYM1 11602.6 H 27.965 1.95E−01 12.9 LYM12113211.8 K 0.546 3.49E−01 14.4 LYM1 11603.2 H 28.246 2.79E−01 14 LYM2412062.3 K 0.547 3.50E−01 14.8 LYM30 11912.6 H 28.163 2.82E−01 13.6 LYM6711782.5 K 0.546 3.51E−01 14.5 LYM14 12051.4 H 29.876 3.41E−01 20.6 LYM5311843.2 K 0.545 3.52E−01 14.3 LYM51 11891.1 H 27.805 3.42E−01 12.2LYM110 12924.5 K 0.548 3.55E−01 15 LYM1 11604.4 H 30.541 3.49E−01 23.2LYM99 12244.2 K 0.549 3.59E−01 15.1 LYM53 11842.4 H 30.36 3.95E−01 22.5LYM12 11871.3 K 0.547 3.66E−01 14.6 LYM31 11924.4 H 28.244 4.58E−01 14LYM99 12244.1 K 0.549 3.66E−01 15.1 LYM57 12012.6 H 29.977 4.61E−01 21LYM271 12724.7 K 0.549 3.69E−01 15.1 LYM13 11771.9 H 26.732 4.87E−01 7.9LYM26 11824.5 K 0.557 3.69E−01 16.8 LYM34 11902.2 H 27.88 5.04E−01 12.5LYM30 11913.5 K 0.544 3.88E−01 14.1 LYM14 12051.1 H 26.648 5.19E−01 7.5LYM67 11781.5 K 0.54 3.88E−01 13.3 LYM21 11674.5 H 25.858 5.35E−01 4.3LYM238 12762.8 K 0.544 3.90E−01 14.1 LYM35 11811.3 H 28.152 5.73E−0113.6 LYM62 12023.4 K 0.544 3.93E−01 14.1 LYM2 11695.1 H 25.97 6.93E−014.8 LYM14 12052.5 K 0.547 3.97E−01 14.8 LYM69 11851.2 H 25.499 6.95E−012.9 LYM31 11921.3 K 0.544 4.06E−01 14 LYM7 11594.2 H 26.064 7.54E−01 5.2LYM26 11821.2 K 0.54 4.06E−01 13.3 LYM13 11771.6 H 25.204 7.64E−01 1.7LYM43 11792.2 K 0.54 4.06E−01 13.3 LYM12 11872.1 H 26.31 7.68E−01 6.2LYM62 12022.4 K 0.54 4.18E−01 13.3 LYM31 11923.4 H 26.115 7.78E−01 5.4LYM271 12721.8 K 0.536 4.26E−01 12.3 LYM34 11903.2 H 27.351 7.84E−0110.4 LYM56 13112.6 K 0.536 4.32E−01 12.4 LYM51 11893.4 H 25.767 7.97E−014 LYM145 12951.9 K 0.535 4.47E−01 12.2 LYM66 11953.6 H 25.492 8.09E−012.9 LYM110 12923.5 K 0.534 4.49E−01 12.1 LYM68 11942.3 H 26.014 8.37E−015 LYM110 12921.7 K 0.537 4.51E−01 12.6 LYM30 11913.4 H 26.041 8.38E−015.1 LYM12 11872.1 K 0.536 4.52E−01 12.3 LYM1 11601.1 H 25.377 8.67E−012.4 LYM20 11711.3 K 0.533 4.57E−01 11.8 LYM24 12061.2 H 25.011 9.20E−010.9 LYM57 12012.2 K 0.534 4.71E−01 11.9 LYM1 11602.1 H 24.992 9.73E−010.9 LYM88 12193.1 K 0.529 4.85E−01 11 LYM53 11844.2 H 24.831 9.74E−010.2 LYM66 11953.6 K 0.53 4.94E−01 11.1 CONTROL — H 24.78 — 0 LYM3111924.4 K 0.53 5.07E−01 11.1 LYM9 11632.1 J 0.079 1.51E−01 24.8 LYM6711782.4 K 0.532 5.13E−01 11.5 LYM57 12013.1 J 0.078 1.83E−01 23 LYM28512731.4 K 0.525 5.18E−01 10 LYM57 12012.6 J 0.077 2.25E−01 21.2 LYM23913041.1 K 0.523 5.35E−01 9.7 LYM30 11912.6 J 0.076 2.26E−01 20.6 LYM2412063.3 K 0.521 5.41E−01 9.2 LYM53 11842.4 J 0.076 2.65E−01 19.4 LYM15612963.1 K 0.522 5.54E−01 9.4 LYM1 11604.4 J 0.075 2.97E−01 18.6 LYM1211874.1 K 0.521 5.55E−01 9.2 LYM1 11603.2 J 0.074 3.28E−01 16.8 LYM27112724.9 K 0.522 5.59E−01 9.5 LYM10 11744.1 J 0.073 3.53E−01 15.7 LYM10312713.7 K 0.52 5.64E−01 9.1 LYM31 11924.4 J 0.072 3.90E−01 14.6 LYM1412054.2 K 0.518 5.72E−01 8.6 LYM14 12051.4 J 0.072 4.24E−01 13.6 LYM5712013.3 K 0.519 5.89E−01 8.9 LYM35 11812.3 J 0.072 4.25E−01 13.3 LYM3111923.1 K 0.515 6.17E−01 7.9 LYM9 11633.7 J 0.071 4.52E−01 12.5 LYM23812761.6 K 0.518 6.24E−01 8.5 LYM34 11902.2 J 0.071 4.57E−01 12.9 LYM23213024.5 K 0.515 6.30E−01 7.9 LYM35 11813.5 J 0.071 4.85E−01 11.8 LYM5613112.7 K 0.512 6.37E−01 7.3 LYM57 12012.4 J 0.07 5.22E−01 10.3 LYM2611824.6 K 0.51 6.47E−01 6.9 LYM51 11891.1 J 0.069 5.53E−01 9.8 LYM10312712.8 K 0.511 6.48E−01 7.2 LYM2 11695.1 J 0.069 5.59E−01 9.8 LYM4111831.1 K 0.509 6.63E−01 6.8 LYM31 11923.4 J 0.069 5.64E−01 9.9 LYM27713101.1 K 0.508 6.88E−01 6.6 LYM13 11771.9 J 0.069 5.93E−01 9 LYM5613111.7 K 0.509 6.88E−01 6.7 LYM68 11942.3 J 0.069 5.94E−01 9.5 LYM28412884.7 K 0.506 6.90E−01 6.2 LYM7 11594.2 J 0.069 5.99E−01 8.8 LYM6212022.1 K 0.504 7.05E−01 5.7 LYM66 11953.6 J 0.069 6.12E−01 8.5 LYM3011912.7 K 0.507 7.06E−01 6.3 LYM14 12051.1 J 0.069 6.16E−01 8.5 LYM4111833.1 K 0.501 7.36E−01 5.1 LYM10 11741.2 J 0.068 6.23E−01 8.2 LYM10312714.6 K 0.502 7.61E−01 5.3 LYM1 11602.6 J 0.068 6.34E−01 7.8 LYM5111891.1 K 0.5 7.77E−01 4.8 LYM12 11872.1 J 0.068 6.36E−01 8 LYM23913042.9 K 0.498 7.78E−01 4.5 LYM69 11852.2 J 0.068 6.55E−01 7.3 LYM2412061.2 K 0.498 7.80E−01 4.5 LYM35 11811.3 J 0.068 6.90E−01 6.8 LYM11613201.8 K 0.495 8.03E−01 3.9 LYM34 11903.2 J 0.068 7.08E−01 6.9 LYM6611953.1 K 0.496 8.07E−01 3.9 LYM13 11771.6 J 0.067 7.11E−01 6.2 LYM27112723.2 K 0.497 8.18E−01 4.3 LYM69 11851.2 J 0.066 7.59E−01 5.1 LYM27713101.8 K 0.495 8.23E−01 3.9 LYM1 11601.1 J 0.065 8.32E−01 3.5 LYM12512934.7 K 0.494 8.28E−01 3.6 LYM51 11893.4 J 0.065 8.37E−01 3.4 LYM12113214.3 K 0.493 8.30E−01 3.4 LYM43 11791.4 J 0.065 8.52E−01 3.1 LYM8812194.2 K 0.492 8.37E−01 3.2 LYM24 12061.2 J 0.065 8.93E−01 2.2 LYM2011716.5 K 0.49 8.59E−01 2.8 LYM53 11844.2 J 0.064 9.21E−01 1.6 LYM5712013.5 K 0.488 8.85E−01 2.3 LYM30 11913.4 J 0.064 9.24E−01 1.6 LYM6611952.2 K 0.488 8.89E−01 2.4 LYM15 11612.2 J 0.064 9.40E−01 1.3 LYM15612961.9 K 0.487 8.92E−01 2.1 LYM21 11674.5 J 0.064 9.43E−01 1.2 LYM6711783.5 K 0.485 9.13E−01 1.7 CONTROL — J 0.063 — 0 LYM232 13022.1 K0.485 9.18E−01 1.8 LYM57 12012.4 K 0.724 2.06E−01 19.4 LYM67 11782.6 K0.483 9.35E−01 1.3 LYM37 11803.2 K 0.711 2.92E−01 17.3 LYM145 12954.7 K0.482 9.41E−01 1.2 LYM26 11824.6 K 0.699 3.16E−01 15.3 LYM125 12932.6 K0.483 9.42E−01 1.4 LYM31 11921.3 K 0.696 3.36E−01 14.9 LYM125 12933.8 K0.481 9.60E−01 0.8 LYM41 11831.1 K 0.695 3.63E−01 14.6 LYM285 12732.5 K0.48 9.74E−01 0.6 LYM62 12023.7 K 0.684 4.19E−01 12.8 LYM156 12961.7 K0.478 9.91E−01 0.2 LYM62 12023.2 K 0.699 4.20E−01 15.4 CONTROL — K 0.477— 0 LYM37 11801.1 K 0.681 4.37E−01 12.4 LYM128 12641.5 L 2.449 2.11E−0459.2 LYM35 11811.3 K 0.68 4.38E−01 12.2 LYM116 13202.12 L 2.375 4.83E−0454.4 LYM69 11852.2 K 0.676 4.46E−01 11.6 LYM12 11872.1 L 2.465 7.52E−0460.2 LYM16 11622.4 K 0.683 4.47E−01 12.6 LYM285 12733.9 L 2.38 9.95E−0454.7 LYM21 11671.2 K 0.674 4.59E−01 11.1 LYM99 12243.1 L 2.246 1.78E−0346 LYM53 11841.2 K 0.674 4.66E−01 11.1 LYM20 11711.2 L 2.203 4.00E−0343.2 LYM24 12062.3 K 0.668 5.01E−01 10.2 LYM26 11824.1 L 2.171 5.72E−0341.1 LYM51 11892.1 K 0.669 5.09E−01 10.3 LYM128 12641.3 L 2.156 5.90E−0340.1 LYM10 11744.1 K 0.668 5.14E−01 10.1 LYM95 12121.2 L 2.155 1.11E−0240.1 LYM34 11902.2 K 0.666 5.18E−01 9.9 LYM67 11782.6 L 2.107 1.18E−0236.9 LYM14 12054.2 K 0.665 5.20E−01 9.7 LYM66 11954.4 L 2.091 1.19E−0235.9 LYM67 11782.6 K 0.66 5.62E−01 8.9 LYM12 11871.1 L 2.088 2.29E−0235.7 LYM9 11632.1 K 0.66 5.63E−01 8.9 LYM24 12061.4 L 2.044 2.38E−0232.9 LYM15 11611.3 K 0.659 6.00E−01 8.7 LYM238 12764.8 L 2.035 2.46E−0232.3 LYM4 11706.5 K 0.655 6.01E−01 8 LYM103 12713.5 L 2.065 2.84E−0234.2 LYM12 11872.1 K 0.656 6.03E−01 8.3 LYM26 11824.3 L 2.01 2.91E−0230.7 LYM35 11812.3 K 0.655 6.07E−01 8 LYM26 11824.6 L 1.98 3.86E−02 28.7LYM62 12022.4 K 0.651 6.30E−01 7.4 LYM239 13042.9 L 1.977 4.34E−02 28.5LYM30 11912.6 K 0.649 6.64E−01 7 LYM53 11841.1 L 1.971 4.77E−02 28.1LYM20 11716.5 K 0.646 6.74E−01 6.6 LYM88 12193.1 L 1.936 5.80E−02 25.8LYM67 11781.5 K 0.643 6.97E−01 6 LYM116 13202.7 L 1.907 8.77E−02 24 LYM411702.3 K 0.64 7.22E−01 5.6 LYM232 13024.7 L 1.971 1.00E−01 28.1 LYM6911851.2 K 0.639 7.23E−01 5.4 LYM69 11852.2 L 1.875 1.06E−01 21.9 LYM6811942.2 K 0.64 7.29E−01 5.6 LYM31 11923.4 L 1.872 1.15E−01 21.7 LYM3511812.4 K 0.643 7.31E−01 6 LYM82 12201.1 L 1.843 1.30E−01 19.8 LYM711592.1 K 0.64 7.32E−01 5.6 LYM95 12124.4 L 1.829 1.51E−01 18.9 LYM3011913.4 K 0.641 7.33E−01 5.8 LYM103 12712.8 L 1.841 1.53E−01 19.6 LYM3011913.3 K 0.638 7.35E−01 5.2 LYM30 11912.6 L 1.842 1.64E−01 19.7 LYM811982.6 K 0.638 7.37E−01 5.2 LYM14 12051.4 L 1.83 1.66E−01 18.9 LYM211692.3 K 0.641 7.40E−01 5.8 LYM26 11824.5 L 1.909 1.69E−01 24.1 LYM411702.1 K 0.634 7.62E−01 4.5 LYM31 11924.4 L 1.818 1.86E−01 18.2 LYM4111832.2 K 0.631 7.80E−01 4.1 LYM12 11871.3 L 1.814 1.86E−01 17.9 LYM911633.2 K 0.634 7.80E−01 4.5 LYM24 12064.1 L 1.814 2.15E−01 17.9 LYM911634.5 K 0.63 8.00E−01 3.9 LYM156 12963.1 L 1.792 2.30E−01 16.4 LYM911632.2 K 0.63 8.04E−01 3.9 LYM232 13024.6 L 1.789 2.39E−01 16.2 LYM5311842.4 K 0.631 8.07E−01 4.1 LYM67 11782.4 L 1.786 2.40E−01 16.1 LYM6811941.3 K 0.629 8.08E−01 3.7 LYM116 13204.4 L 1.859 2.45E−01 20.8 LYM1311771.9 K 0.629 8.13E−01 3.7 LYM99 12244.2 L 1.772 2.57E−01 15.2 LYM5712012.2 K 0.626 8.34E−01 3.3 LYM239 13044.8 L 1.776 2.66E−01 15.4 LYM2111674.1 K 0.624 8.48E−01 2.9 LYM26 11821.2 L 1.773 2.99E−01 15.3 LYM3411902.4 K 0.624 8.48E−01 2.9 LYM20 11716.5 L 1.749 3.04E−01 13.7 LYM4111833.1 K 0.624 8.52E−01 2.9 LYM128 12641.1 L 1.763 3.04E−01 14.6 LYM111604.4 K 0.62 8.86E−01 2.3 LYM53 11843.2 L 1.746 3.06E−01 13.5 LYM911633.7 K 0.62 8.87E−01 2.3 LYM66 11955.2 L 1.74 3.08E−01 13.1 LYM1711683.1 K 0.619 8.89E−01 2.1 LYM62 12023.2 L 1.735 3.31E−01 12.7 LYM1511614.4 K 0.618 9.03E−01 1.9 LYM88 12194.2 L 1.681 4.65E−01 9.3 LYM2011716.3 K 0.618 9.05E−01 1.9 LYM43 11791.4 L 1.687 4.68E−01 9.6 LYM6212022.2 K 0.616 9.13E−01 1.7 LYM12 11873.4 L 1.658 5.55E−01 7.8 LYM411705.2 K 0.616 9.15E−01 1.7 LYM30 11913.5 L 1.667 5.55E−01 8.3 LYM2111674.5 K 0.615 9.26E−01 1.5 LYM30 11912.7 L 1.652 5.73E−01 7.4 LYM2611824.3 K 0.615 9.27E−01 1.5 LYM30 11913.4 L 1.644 6.15E−01 6.8 LYM6911854.2 K 0.615 9.30E−01 1.5 LYM103 12711.8 L 1.637 6.20E−01 6.4 LYM6711783.4 K 0.611 9.57E−01 0.8 LYM43 11793.2 L 1.645 6.21E−01 6.9 LYM3711801.2 K 0.611 9.57E−01 0.8 LYM99 12243.2 L 1.628 6.46E−01 5.8 LYM6711782.5 K 0.61 9.67E−01 0.6 LYM66 11953.6 L 1.627 6.52E−01 5.7 LYM6212023.4 K 0.61 9.70E−01 0.6 LYM103 12712.5 L 1.629 6.58E−01 5.9 LYM711594.2 K 0.61 9.70E−01 0.6 LYM285 12734.9 L 1.608 7.44E−01 4.5 LYM1611624.4 K 0.609 9.77E−01 0.4 LYM145 12951.9 L 1.593 7.83E−01 3.5 LYM711591.5 K 0.609 9.79E−01 0.4 LYM103 12714.6 L 1.595 8.01E−01 3.7 LYM3111922.3 K 0.608 9.89E−01 0.2 LYM62 12023.5 L 1.586 8.08E−01 3.1 LYM811984.1 K 0.606 1.00E+00 0 LYM238 12762.8 L 1.587 8.13E−01 3.1 CONTROL —K 0.606 — 0 LYM43 11791.5 L 1.576 8.47E−01 2.4 LYM9 11632.1 L 4.4644.79E−02 36.6 LYM156 12961.9 L 1.57 8.76E−01 2 LYM10 11744.1 L 4.1661.32E−01 27.5 LYM57 12012.2 L 1.551 9.48E−01 0.8 LYM53 11842.4 L 4.0362.03E−01 23.5 LYM20 11716.3 L 1.551 9.50E−01 0.8 LYM1 11604.4 L 4.0262.08E−01 23.2 LYM24 12062.3 L 1.546 9.69E−01 0.5 LYM57 12012.6 L 3.9622.47E−01 21.3 CONTROL — L 1.539 — 0 LYM14 12051.4 L 3.941 2.56E−01 20.6LYM128 12641.5 M 0.306 5.45E−04 53.9 LYM57 12013.1 L 3.929 2.56E−01 20.2LYM116 13202.12 M 0.297 1.21E−03 49.2 LYM35 11812.3 L 3.814 3.35E−0116.7 LYM12 11872.1 M 0.308 1.61E−03 54.8 LYM30 11912.6 L 3.736 4.19E−0114.3 LYM285 12733.9 M 0.298 2.23E−03 49.5 LYM31 11924.4 L 3.738 4.20E−0114.4 LYM99 12243.1 M 0.281 4.33E−03 41.1 LYM57 12012.4 L 3.713 4.26E−0113.6 LYM20 11711.2 M 0.275 8.94E−03 38.4 LYM35 11811.3 L 3.73 4.30E−0114.2 LYM26 11824.1 M 0.271 1.25E−02 36.4 LYM1 11603.2 L 3.705 4.48E−0113.4 LYM128 12641.3 M 0.269 1.31E−02 35.4 LYM9 11633.7 L 3.674 4.69E−0112.4 LYM95 12121.2 M 0.269 2.19E−02 35.4 LYM51 11891.1 L 3.68 4.70E−0112.6 LYM67 11782.6 M 0.263 2.45E−02 32.3 LYM35 11813.5 L 3.677 4.70E−0112.5 LYM66 11954.4 M 0.261 2.53E−02 31.3 LYM34 11902.2 L 3.687 4.71E−0112.8 LYM12 11871.1 M 0.261 4.25E−02 31.2 LYM1 11602.6 L 3.671 4.75E−0112.3 LYM24 12061.4 M 0.256 4.64E−02 28.4 LYM69 11852.2 L 3.634 5.13E−0111.2 LYM238 12764.8 M 0.254 4.83E−02 27.8 LYM34 11903.2 L 3.605 5.97E−0110.3 LYM103 12713.5 M 0.258 5.18E−02 29.7 LYM13 11771.9 L 3.541 6.32E−018.4 LYM26 11824.3 M 0.251 5.70E−02 26.3 LYM10 11741.2 L 3.518 6.56E−017.7 LYM26 11824.6 M 0.248 7.39E−02 24.4 LYM12 11872.1 L 3.507 6.78E−017.3 LYM239 13042.9 M 0.247 8.11E−02 24.2 LYM14 12051.1 L 3.504 6.80E−017.2 LYM53 11841.1 M 0.246 8.78E−02 23.8 LYM7 11594.2 L 3.493 6.89E−016.9 LYM88 12193.1 M 0.242 1.07E−01 21.6 LYM31 11923.4 L 3.441 7.61E−015.3 LYM116 13202.7 M 0.238 1.51E−01 19.8 LYM2 11695.1 L 3.433 7.69E−015.1 LYM232 13024.7 M 0.246 1.54E−01 23.8 LYM68 11942.3 L 3.44 7.72E−015.3 LYM69 11852.2 M 0.234 1.83E−01 17.8 LYM30 11913.4 L 3.435 7.78E−015.1 LYM31 11923.4 M 0.234 1.95E−01 17.6 LYM51 11893.4 L 3.402 8.13E−014.1 LYM82 12201.1 M 0.23 2.22E−01 15.8 LYM69 11851.2 L 3.391 8.26E−013.8 LYM26 11824.5 M 0.239 2.44E−01 19.9 LYM21 11674.5 L 3.385 8.32E−013.6 LYM103 12712.8 M 0.23 2.49E−01 15.6 LYM66 11953.6 L 3.366 8.62E−01 3LYM95 12124.4 M 0.229 2.51E−01 14.9 LYM1 11601.1 L 3.336 9.04E−01 2.1LYM30 11912.6 M 0.23 2.60E−01 15.7 LYM13 11771.6 L 3.324 9.20E−01 1.7LYM14 12051.4 M 0.229 2.67E−01 14.9 LYM24 12061.2 L 3.304 9.49E−01 1.1LYM31 11924.4 M 0.227 2.94E−01 14.2 LYM1 11602.1 L 3.288 9.72E−01 0.6LYM12 11871.3 M 0.227 2.96E−01 14 LYM7 11592.1 L 3.269 9.97E−01 0.1LYM24 12064.1 M 0.227 3.27E−01 14 CONTROL — L 3.268 — 0 LYM116 13204.4 M0.232 3.38E−01 16.8 LYM9 11632.1 M 0.558 5.61E−02 34.5 LYM156 12963.1 M0.224 3.54E−01 12.6 LYM10 11744.1 M 0.521 1.52E−01 25.5 LYM232 13024.6 M0.224 3.65E−01 12.4 LYM53 11842.4 M 0.505 2.31E−01 21.6 LYM67 11782.4 M0.223 3.66E−01 12.2 LYM1 11604.4 M 0.503 2.37E−01 21.3 LYM99 12244.2 M0.222 3.92E−01 11.3 LYM30 11912.6 M 0.498 2.52E−01 20.1 LYM239 13044.8 M0.222 3.98E−01 11.6 LYM57 12012.6 M 0.495 2.79E−01 19.4 LYM26 11821.2 M0.222 4.31E−01 11.4 LYM14 12051.4 M 0.493 2.90E−01 18.8 LYM128 12641.1 M0.22 4.42E−01 10.8 LYM57 12013.1 M 0.491 2.91E−01 18.4 LYM20 11716.5 M0.219 4.53E−01 9.9 LYM35 11812.3 M 0.477 3.79E−01 14.9 LYM53 11843.2 M0.218 4.57E−01 9.7 LYM31 11924.4 M 0.467 4.69E−01 12.6 LYM66 11955.2 M0.218 4.64E−01 9.3 LYM57 12012.4 M 0.464 4.78E−01 11.9 LYM62 12023.2 M0.217 4.90E−01 9 LYM35 11811.3 M 0.466 4.79E−01 12.4 LYM43 11791.4 M0.211 6.50E−01 6 LYM1 11603.2 M 0.463 5.00E−01 11.7 LYM88 12194.2 M 0.216.56E−01 5.6 LYM51 11891.1 M 0.46 5.23E−01 10.9 LYM30 11913.5 M 0.2087.36E−01 4.7 LYM9 11633.7 M 0.459 5.24E−01 10.7 LYM12 11873.4 M 0.2077.49E−01 4.2 LYM34 11902.2 M 0.461 5.24E−01 11.1 LYM30 11912.7 M 0.2077.70E−01 3.8 LYM35 11813.5 M 0.46 5.24E−01 10.8 LYM43 11793.2 M 0.2068.08E−01 3.4 LYM1 11602.6 M 0.459 5.29E−01 10.6 LYM30 11913.4 M 0.2058.09E−01 3.3 LYM69 11852.2 M 0.454 5.70E−01 9.5 LYM103 12711.8 M 0.2058.25E−01 2.8 LYM34 11903.2 M 0.451 6.52E−01 8.6 LYM238 12763.7 M 0.2048.41E−01 2.5 LYM13 11771.9 M 0.443 6.95E−01 6.7 LYM99 12243.2 M 0.2048.56E−01 2.3 LYM10 11741.2 M 0.44 7.21E−01 6 LYM103 12712.5 M 0.2048.60E−01 2.3 LYM12 11872.1 M 0.438 7.42E−01 5.7 LYM66 11953.6 M 0.2038.63E−01 2.2 LYM14 12051.1 M 0.438 7.44E−01 5.6 LYM285 12734.9 M 0.2019.42E−01 1 LYM7 11594.2 M 0.437 7.55E−01 5.3 LYM31 11921.3 M 0.29.69E−01 0.5 LYM31 11923.4 M 0.43 8.29E−01 3.7 LYM103 12714.6 M 0.1999.90E−01 0.2 LYM68 11942.3 M 0.43 8.37E−01 3.7 LYM145 12951.9 M 0.1999.95E−01 0.1 LYM2 11695.1 M 0.429 8.38E−01 3.5 CONTROL — M 0.199 — 0LYM30 11913.4 M 0.429 8.44E−01 3.5 LYM116 13202.12 N 0.255 2.10E−05 39.1LYM51 11893.4 M 0.425 8.82E−01 2.5 LYM12 11872.1 N 0.263 2.76E−04 43.6LYM69 11851.2 M 0.424 8.97E−01 2.2 LYM128 12641.5 N 0.241 3.00E−04 31.6LYM21 11674.5 M 0.423 9.04E−01 2 LYM20 11711.2 N 0.234 6.41E−04 28 LYM6611953.6 M 0.421 9.33E−01 1.4 LYM238 12764.8 N 0.236 7.16E−04 29.2 LYM111601.1 M 0.417 9.76E−01 0.5 LYM26 11824.1 N 0.234 1.33E−03 28 LYM1311771.6 M 0.415 9.93E−01 0.2 LYM128 12641.3 N 0.232 1.75E−03 26.7CONTROL — M 0.415 — 0 LYM103 12713.5 N 0.231 2.00E−03 26.5 LYM9 11632.1N 0.364 3.31E−01 10.1 LYM24 12061.4 N 0.227 3.42E−03 24.1 LYM30 11912.6N 0.363 3.56E−01 9.8 LYM232 13024.6 N 0.228 3.85E−03 24.4 LYM53 11842.4N 0.363 3.57E−01 10.1 LYM285 12733.9 N 0.229 4.57E−03 25 LYM57 12012.4 N0.357 4.27E−01 8.1 LYM26 11824.3 N 0.226 4.79E−03 23.5 LYM35 11813.5 N0.356 4.55E−01 7.8 LYM66 11954.4 N 0.224 5.52E−03 22.5 LYM35 11811.3 N0.357 4.59E−01 8.1 LYM239 13042.9 N 0.226 5.90E−03 23.3 LYM57 12013.1 N0.355 4.83E−01 7.5 LYM30 11912.6 N 0.227 6.07E−03 24 LYM14 12051.4 N0.352 5.51E−01 6.5 LYM128 12641.1 N 0.225 9.15E−03 23.1 LYM9 11633.7 N0.349 5.80E−01 5.6 LYM116 13202.7 N 0.221 1.09E−02 20.9 LYM57 12012.6 N0.349 5.90E−01 5.8 LYM31 11924.4 N 0.221 1.24E−02 21 LYM43 11791.4 N0.347 6.19E−01 5.2 LYM12 11871.1 N 0.226 1.29E−02 23.3 LYM68 11942.3 N0.348 6.27E−01 5.5 LYM14 12051.4 N 0.22 1.51E−02 20.4 LYM31 11924.4 N0.346 6.55E−01 4.8 LYM24 12064.1 N 0.226 1.54E−02 23.5 LYM34 11902.2 N0.345 6.78E−01 4.4 LYM103 12712.8 N 0.219 1.66E−02 19.4 LYM51 11891.1 N0.344 6.78E−01 4.2 LYM53 11841.1 N 0.219 1.67E−02 19.7 LYM10 11744.1 N0.344 6.92E−01 4.2 LYM95 12121.2 N 0.22 1.74E−02 20.4 LYM66 11953.6 N0.341 7.64E−01 3.2 LYM30 11913.5 N 0.224 1.83E−02 22.5 LYM1 11604.4 N0.34 7.75E−01 3.1 LYM31 11923.4 N 0.217 2.07E−02 18.9 LYM37 11801.1 N0.339 8.01E−01 2.5 LYM232 13024.7 N 0.235 2.12E−02 28.2 LYM13 11771.9 N0.338 8.16E−01 2.5 LYM99 12243.1 N 0.22 2.16E−02 20.1 LYM7 11594.2 N0.337 8.44E−01 2.1 LYM239 13044.8 N 0.217 2.68E−02 18.4 LYM1 11603.2 N0.337 8.51E−01 2 LYM26 11824.6 N 0.217 2.69E−02 18.4 LYM13 11771.6 N0.336 8.71E−01 1.7 LYM116 13204.4 N 0.233 2.78E−02 27.6 LYM35 11812.3 N0.336 8.72E−01 1.7 LYM12 11871.3 N 0.218 3.06E−02 18.9 LYM9 11633.2 N0.335 8.86E−01 1.5 LYM67 11782.6 N 0.215 3.30E−02 17.4 LYM69 11852.2 N0.333 9.38E−01 0.8 LYM53 11843.2 N 0.212 4.67E−02 15.7 LYM12 11872.1 N0.333 9.45E−01 0.8 LYM103 12712.5 N 0.212 5.01E−02 16.1 LYM35 11811.2 N0.331 9.70E−01 0.4 LYM30 11913.4 N 0.213 5.21E−02 16.1 LYM34 11903.2 N0.331 9.79E−01 0.3 LYM88 12193.1 N 0.211 5.46E−02 15.1 CONTROL — N 0.33— 0 LYM238 12762.8 N 0.211 5.60E−02 15.4 LYM9 11632.1 O 4.239 1.94E−0434.8 LYM12 11873.4 N 0.211 5.78E−02 15.1 LYM30 11912.6 O 3.754 6.17E−0319.4 LYM26 11821.2 N 0.215 6.72E−02 17.8 LYM57 12013.1 O 3.697 1.13E−0217.5 LYM69 11852.2 N 0.21 6.75E−02 14.7 LYM35 11812.3 O 3.65 1.50E−02 16LYM285 12734.9 N 0.212 7.54E−02 16.1 LYM10 11744.1 O 3.955 1.30E−01 25.7LYM26 11824.5 N 0.222 7.68E−02 21.1 LYM57 12012.4 O 3.453 1.41E−01 9.8LYM156 12961.9 N 0.208 7.99E−02 13.9 LYM35 11813.5 O 3.499 1.51E−01 11.2LYM43 11791.4 N 0.208 8.13E−02 13.6 LYM10 11741.2 O 3.37 2.00E−01 7.1LYM99 12244.2 N 0.207 8.64E−02 13.3 LYM9 11633.7 O 3.495 2.27E−01 11.1LYM238 12763.7 N 0.205 1.20E−01 12 LYM69 11852.2 O 3.439 2.27E−01 9.3LYM156 12963.1 N 0.208 1.24E−01 13.5 LYM1 11602.6 O 3.496 2.38E−01 11.1LYM82 12201.1 N 0.204 1.29E−01 11.7 LYM1 11603.2 O 3.531 3.22E−01 12.2LYM95 12124.4 N 0.204 1.34E−01 11.7 LYM14 12051.4 O 3.735 3.69E−01 18.7LYM20 11716.5 N 0.204 1.46E−01 11.3 LYM1 11604.4 O 3.818 3.73E−01 21.4LYM31 11921.3 N 0.203 1.70E−01 10.9 LYM51 11891.1 O 3.476 3.93E−01 10.5LYM145 12951.9 N 0.202 1.80E−01 10.4 LYM53 11842.4 O 3.795 4.20E−01 20.6LYM30 11912.7 N 0.202 1.85E−01 10.1 LYM57 12012.6 O 3.747 4.88E−01 19.1LYM67 11782.4 N 0.203 2.23E−01 11.2 LYM31 11924.4 O 3.531 5.00E−01 12.2LYM20 11712.2 N 0.203 2.24E−01 10.7 LYM34 11902.2 O 3.485 5.50E−01 10.8LYM285 12734.7 N 0.2 2.27E−01 9.4 LYM13 11771.9 O 3.342 5.66E−01 6.2LYM103 12714.6 N 0.204 2.42E−01 11.7 LYM14 12051.1 O 3.331 5.99E−01 5.9LYM20 11716.3 N 0.2 2.43E−01 9.3 LYM35 11811.3 O 3.519 6.11E−01 11.9LYM62 12023.2 N 0.2 2.46E−01 9.3 LYM21 11674.5 O 3.232 6.76E−01 2.8LYM66 11953.6 N 0.197 3.17E−01 7.7 LYM2 11695.1 O 3.246 7.85E−01 3.2LYM238 12763.5 N 0.197 3.17E−01 7.7 LYM34 11903.2 O 3.419 8.15E−01 8.7LYM232 13024.5 N 0.197 3.18E−01 7.7 LYM12 11872.1 O 3.289 8.23E−01 4.5LYM24 12062.3 N 0.197 3.20E−01 7.7 LYM7 11594.2 O 3.258 8.24E−01 3.6LYM239 13044.7 N 0.197 3.34E−01 7.9 LYM31 11923.4 O 3.264 8.39E−01 3.8LYM57 12012.2 N 0.196 3.40E−01 7.3 LYM69 11851.2 O 3.187 8.50E−01 1.3LYM103 12711.8 N 0.195 4.17E−01 6.4 LYM51 11893.4 O 3.221 8.73E−01 2.4LYM53 11842.4 N 0.194 4.55E−01 5.8 LYM30 11913.4 O 3.255 8.86E−01 3.5LYM88 12194.2 N 0.193 4.99E−01 5.2 LYM68 11942.3 O 3.252 8.86E−01 3.4LYM145 12954.8 N 0.194 5.03E−01 6.2 LYM66 11953.6 O 3.186 9.10E−01 1.3LYM121 13212.6 N 0.193 5.34E−01 5.4 LYM1 11601.1 O 3.172 9.52E−01 0.8LYM232 13024.4 N 0.194 5.39E−01 6.1 LYM13 11771.6 O 3.151 9.76E−01 0.2LYM67 11782.5 N 0.19 5.94E−01 4.1 CONTROL — O 3.146 — 0 LYM43 11793.2 N0.192 5.99E−01 4.7 LYM9 11632.1 P 3.799 3.19E−03 12.7 LYM145 12954.7 N0.192 6.07E−01 4.8 LYM10 11744.1 P 3.642 4.04E−02 8 LYM277 13103.1 N0.19 6.17E−01 3.9 LYM57 12012.4 P 3.618 9.72E−02 7.3 LYM121 13211.8 N0.19 6.20E−01 3.8 LYM30 11912.6 P 3.638 1.05E−01 7.9 LYM53 11844.2 N0.189 6.49E−01 3.5 LYM9 11633.7 P 3.554 1.21E−01 5.4 LYM128 12642.1 N0.19 6.64E−01 3.8 LYM35 11813.5 P 3.611 1.25E−01 7.1 LYM20 11711.3 N0.189 6.73E−01 3.3 LYM35 11812.3 P 3.533 1.68E−01 4.8 LYM238 12761.6 N0.19 6.91E−01 3.7 LYM57 12013.1 P 3.581 1.87E−01 6.2 LYM66 11955.2 N0.188 7.07E−01 2.9 LYM53 11842.4 P 3.713 3.40E−01 10.1 LYM41 11831.5 N0.188 7.21E−01 2.7 LYM14 12051.4 P 3.67 3.72E−01 8.9 LYM239 13041.7 N0.188 7.27E−01 2.8 LYM1 11603.2 P 3.508 4.36E−01 4.1 LYM145 12952.9 N0.189 7.54E−01 3.5 LYM35 11811.3 P 3.641 4.94E−01 8 LYM41 11834.2 N0.188 7.59E−01 2.7 LYM51 11891.1 P 3.47 5.07E−01 2.9 LYM277 13101.1 N0.186 8.04E−01 1.9 LYM13 11771.9 P 3.469 5.23E−01 2.9 LYM24 12063.3 N0.186 8.26E−01 1.8 LYM57 12012.6 P 3.6 5.25E−01 6.8 LYM99 12243.2 N0.185 8.58E−01 1.4 LYM1 11604.4 P 3.57 5.61E−01 5.9 LYM239 13041.1 N0.186 8.59E−01 1.6 LYM31 11924.4 P 3.505 5.77E−01 4 LYM43 11791.5 N0.185 8.70E−01 1.2 LYM34 11902.2 P 3.484 6.13E−01 3.3 LYM156 12961.7 N0.185 9.12E−01 0.9 LYM37 11801.1 P 3.43 6.41E−01 1.7 LYM31 11923.1 N0.185 9.12E−01 0.9 LYM1 11602.6 P 3.472 6.46E−01 3 LYM62 12023.5 N 0.1849.24E−01 0.7 LYM13 11771.6 P 3.42 6.49E−01 1.4 LYM156 12963.4 N 0.1859.26E−01 1 LYM7 11594.2 P 3.454 7.12E−01 2.4 LYM116 13201.8 N 0.1849.37E−01 0.6 LYM68 11942.3 P 3.496 7.55E−01 3.7 LYM41 11832.2 N 0.1849.65E−01 0.4 LYM14 12051.1 P 3.422 7.70E−01 1.5 LYM110 12924.5 N 0.1839.85E−01 0.2 LYM12 11872.1 P 3.447 8.61E−01 2.2 CONTROL — N 0.183 — 0LYM43 11791.4 P 3.388 8.73E−01 0.5 LYM116 13202.12 O 2.289 9.00E−06 42.6LYM34 11903.2 P 3.431 9.24E−01 1.8 LYM88 12193.1 O 1.96 6.36E−04 22.1LYM35 11811.2 P 3.39 9.29E−01 0.5 LYM20 11711.2 O 2.141 2.08E−03 33.4LYM69 11852.2 P 3.381 9.42E−01 0.3 LYM53 11841.1 O 1.955 4.31E−03 21.8LYM30 11913.4 P 3.387 9.73E−01 0.4 LYM67 11782.6 O 2.097 4.70E−03 30.6CONTROL — P 3.372 — 0 LYM31 11923.4 O 1.855 4.75E−03 15.6 LYM128 12641.3A 93.331 6.75E−03 3.8 LYM82 12201.1 O 1.863 2.54E−02 16.1 LYM90 12393.2A 93.321 6.94E−03 3.8 LYM26 11824.3 O 1.919 3.12E−02 19.6 LYM86 12183.1A 93.089 9.82E−03 3.5 LYM238 12764.8 O 1.942 3.40E−02 21 LYM89 12211.4 A92.845 1.42E−02 3.2 LYM12 11871.3 O 1.754 6.30E−02 9.3 LYM149 12343.1 A92.942 1.62E−02 3.4 LYM128 12641.5 O 2.376 6.82E−02 48.1 LYM157 13341.7A 94.877 1.64E−02 5.5 LYM99 12243.1 O 2.287 8.62E−02 42.5 LYM178 12163.4A 92.918 1.64E−02 3.3 LYM26 11824.1 O 2.088 9.91E−02 30.1 LYM90 12393.1A 92.555 2.23E−02 2.9 LYM128 12641.3 O 2.096 1.04E−01 30.6 LYM12812642.3 A 92.517 2.39E−02 2.9 LYM99 12244.2 O 1.757 1.07E−01 9.5 LYM9912243.2 A 92.543 2.43E−02 2.9 LYM88 12194.2 O 1.705 1.51E−01 6.2 LYM20612601.3 A 93.451 2.44E−02 3.9 LYM239 13042.9 O 1.915 1.56E−01 19.3LYM129 12573.5 A 92.522 2.60E−02 2.9 LYM53 11843.2 O 1.719 1.75E−01 7.1LYM107 12631.4 A 92.899 2.65E−02 3.3 LYM285 12733.9 O 2.366 1.77E−0147.4 LYM86 12182.3 A 93.033 2.93E−02 3.5 LYM26 11824.6 O 1.955 1.91E−0121.8 LYM128 12641.1 A 92.897 2.99E−02 3.3 LYM24 12061.4 O 1.984 1.96E−0123.6 LYM178 12163.3 A 92.504 3.08E−02 2.9 LYM103 12713.5 O 2.0292.03E−01 26.4 LYM149 12344.2 A 92.323 3.24E−02 2.7 LYM66 11954.4 O 2.0632.20E−01 28.5 LYM73 12623.2 A 92.762 3.28E−02 3.2 LYM12 11872.1 O 2.3942.31E−01 49.2 LYM6 11735.1 A 92.326 3.43E−02 2.7 LYM116 13202.7 O 1.8152.36E−01 13.1 LYM86 12181.3 A 93.242 4.14E−02 3.7 LYM95 12124.4 O 1.8142.85E−01 13 LYM250 12613.2 A 92.215 4.16E−02 2.5 LYM31 11924.4 O 1.7853.22E−01 11.2 LYM250 12613.4 A 92.165 4.20E−02 2.5 LYM20 11716.5 O 1.7083.22E−01 6.4 LYM89 12214.2 A 92.355 4.43E−02 2.7 LYM66 11955.2 O 1.7653.26E−01 10 LYM90 12395.3 A 92.938 4.47E−02 3.4 LYM95 12121.2 O 2.1423.32E−01 33.5 LYM86 12183.3 A 92.937 4.54E−02 3.4 LYM12 11871.1 O 2.033.52E−01 26.5 LYM157 13341.4 A 92.35 4.58E−02 2.7 LYM69 11852.2 O 1.8153.82E−01 13.1 LYM129 12573.3 A 92.84 4.79E−02 3.2 LYM14 12051.4 O 1.7824.01E−01 11 LYM6 11734.3 A 92.288 5.09E−02 2.6 LYM103 12712.8 O 1.7595.04E−01 9.6 LYM256 13322.3 A 92.641 6.65E−02 3 LYM239 13044.8 O 1.7355.52E−01 8.1 LYM157 13342.4 A 94.106 7.45E−02 4.7 LYM67 11782.4 O 1.7755.69E−01 10.6 LYM88 12191.2 A 91.953 7.61E−02 2.3 LYM43 11791.4 O 1.6695.91E−01 4 LYM99 12244.1 A 93.509 7.70E−02 4 LYM30 11912.7 O 1.6395.96E−01 2.1 LYM178 12164.3 A 91.816 8.24E−02 2.1 LYM30 11912.6 O 1.7366.07E−01 8.1 LYM250 12614.1 A 91.729 8.76E−02 2 LYM232 13024.7 O 1.9266.15E−01 20 LYM90 12395.1 A 93.165 8.97E−02 3.6 LYM62 12023.2 O 1.6856.23E−01 5 LYM91 13283.4 A 91.631 1.00E−01 1.9 LYM232 13024.6 O 1.6866.28E−01 5.1 LYM178 12161.2 A 92.239 1.02E−01 2.6 LYM66 11953.6 O 1.6356.53E−01 1.9 LYM129 12571.3 A 91.667 1.10E−01 1.9 LYM156 12963.1 O 1.7116.79E−01 6.6 LYM256 13323.3 A 93.178 1.29E−01 3.6 LYM26 11824.5 O 1.8666.82E−01 16.3 LYM107 12633.4 A 91.472 1.31E−01 1.7 LYM128 12641.1 O1.684 7.51E−01 4.9 LYM91 13283.1 A 93.948 1.50E−01 4.5 LYM24 12064.1 O1.711 7.64E−01 6.6 LYM88 12193.1 A 91.377 1.54E−01 1.6 LYM26 11821.2 O1.706 7.79E−01 6.3 LYM157 13341.1 A 93.647 1.57E−01 4.1 LYM116 13204.4 O1.779 8.04E−01 10.8 LYM90 12392.1 A 92.786 1.71E−01 3.2 LYM99 12243.2 O1.63 8.51E−01 1.6 LYM147 12583.3 A 91.846 1.98E−01 2.1 LYM43 11793.2 O1.63 9.41E−01 1.6 LYM6 11735.2 A 92.319 2.06E−01 2.7 LYM30 11913.5 O1.606 9.98E−01 0.1 LYM107 12631.2 A 92.349 2.08E−01 2.7 CONTROL — O1.605 — 0 LYM250 12614.2 A 91.184 2.30E−01 1.4 LYM20 11711.2 P 2.4382.52E−04 17.1 LYM283 13304.4 A 91.862 2.32E−01 2.2 LYM238 12764.8 P2.357 1.15E−03 13.2 LYM147 12584.4 A 91.139 2.56E−01 1.4 LYM116 13202.12P 2.552 3.04E−03 22.6 LYM99 12243.1 A 91.086 2.57E−01 1.3 LYM53 11841.1P 2.338 3.08E−03 12.3 LYM88 12192.1 A 91.579 2.62E−01 1.8 LYM82 12201.1P 2.294 5.04E−03 10.2 LYM283 13304.5 A 91.337 2.62E−01 1.6 LYM31 11923.4P 2.284 6.11E−03 9.7 LYM73 12623.1 A 92.42 2.83E−01 2.8 LYM88 12193.1 P2.393 7.93E−03 14.9 LYM147 12581.4 A 91.997 2.92E−01 2.3 LYM67 11782.6 P2.393 1.64E−02 14.9 LYM89 12214.3 A 91.734 2.94E−01 2 LYM128 12641.5 P2.579 3.82E−02 23.9 LYM283 13302.2 A 90.934 2.99E−01 1.1 LYM99 12244.2 P2.243 4.31E−02 7.7 LYM256 13321.2 A 92.248 3.12E−01 2.6 LYM12 11871.3 P2.21 4.39E−02 6.1 LYM159 13354.6 A 91.458 3.15E−01 1.7 LYM285 12733.9 P2.538 4.87E−02 21.9 LYM129 12572.2 A 91.727 3.32E−01 2 LYM26 11824.3 P2.31 5.40E−02 10.9 LYM178 12164.2 A 92.077 3.32E−01 2.4 LYM24 12061.4 P2.344 5.96E−02 12.5 LYM88 12191.1 A 93.357 3.33E−01 3.8 LYM128 12641.3 P2.412 6.15E−02 15.8 LYM250 12611.3 A 91.245 3.42E−01 1.5 LYM53 11843.2 P2.23 6.53E−02 7.1 LYM283 13302.1 A 90.834 3.50E−01 1 LYM66 11954.4 P2.443 6.54E−02 17.3 LYM91 13284.3 A 90.961 3.56E−01 1.2 LYM43 11791.4 P2.211 6.54E−02 6.2 LYM147 12584.5 A 93.996 4.12E−01 4.5 LYM99 12243.1 P2.582 9.80E−02 24 LYM159 13352.4 A 91.01 4.60E−01 1.2 LYM31 11924.4 P2.269 1.13E−01 9 LYM283 13303.2 A 91.406 4.71E−01 1.6 LYM103 12713.5 P2.421 1.17E−01 16.3 LYM107 12632.1 A 91.645 4.88E−01 1.9 LYM88 12194.2 P2.185 1.24E−01 4.9 LYM129 12572.4 A 90.878 5.03E−01 1.1 LYM26 11824.6 P2.334 1.30E−01 12.1 LYM89 12214.4 A 93.157 5.04E−01 3.6 LYM66 11955.2 P2.2 1.41E−01 5.6 LYM128 12642.2 A 91.558 5.33E−01 1.8 LYM12 11872.1 P2.739 1.65E−01 31.5 LYM256 13321.3 A 91.538 5.33E−01 1.8 LYM116 13202.7P 2.163 1.71E−01 3.9 LYM206 12603.3 A 91.15 5.58E−01 1.4 LYM95 12121.2 P2.456 1.79E−01 17.9 LYM236 12592.3 A 91.439 5.75E−01 1.7 LYM26 11824.1 P2.389 2.02E−01 14.7 LYM236 12594.3 A 91.377 6.02E−01 1.6 LYM12 11873.4 P2.153 2.17E−01 3.4 LYM236 12592.4 A 90.999 6.25E−01 1.2 LYM239 13044.8 P2.223 2.38E−01 6.7 LYM147 12583.1 A 90.912 6.62E−01 1.1 LYM66 11953.6 P2.169 2.58E−01 4.2 LYM149 12341.1 A 91.327 6.71E−01 1.6 LYM239 13042.9 P2.33 2.67E−01 11.9 LYM73 12622.2 A 91.911 6.73E−01 2.2 LYM232 13024.6 P2.221 2.68E−01 6.6 LYM206 12601.2 A 90.459 7.06E−01 0.6 LYM12 11871.1 P2.378 3.29E−01 14.2 LYM206 12603.1 A 90.27 7.13E−01 0.4 LYM95 12124.4 P2.245 3.30E−01 7.8 LYM6 11733.2 A 90.249 7.32E−01 0.4 LYM14 12051.4 P2.234 3.46E−01 7.3 LYM256 13324.2 A 90.178 7.88E−01 0.3 LYM30 11912.7 P2.134 3.65E−01 2.5 LYM149 12341.3 A 90.221 7.91E−01 0.3 LYM62 12023.2 P2.202 3.71E−01 5.7 LYM91 13284.4 A 90.429 8.53E−01 0.6 LYM103 12712.8 P2.201 3.96E−01 5.7 LYM6 11736.1 A 90.297 9.04E−01 0.4 LYM20 11716.5 P2.155 4.05E−01 3.5 LYM236 12593.4 A 90.02 9.77E−01 0.1 LYM69 11852.2 P2.188 4.52E−01 5.1 LYM89 12211.2 A 89.955 9.84E−01 0 LYM30 11912.6 P2.202 5.00E−01 5.7 CONTROL — A 89.923 — 0 LYM145 12951.9 P 2.1175.23E−01 1.7 LYM99 12243.1 B 0.444 1.98E−03 23 LYM128 12641.1 P 2.195.43E−01 5.2 LYM178 12163.3 B 0.408 2.91E−02 13.1 LYM67 11782.4 P 2.2215.46E−01 6.7 LYM283 13302.1 B 0.491 3.45E−02 36 LYM232 13024.7 P 2.3665.92E−01 13.6 LYM159 13354.6 B 0.406 1.13E−01 12.6 LYM30 11913.5 P 2.216.02E−01 6.1 LYM129 12573.5 B 0.409 1.16E−01 13.3 LYM26 11824.5 P 2.2686.14E−01 8.9 LYM250 12613.4 B 0.403 1.57E−01 11.6 LYM116 13204.4 P 2.2926.62E−01 10.1 LYM178 12164.2 B 0.399 2.93E−01 10.5 LYM156 12961.9 P2.106 6.63E−01 1.1 LYM236 12594.3 B 0.391 2.93E−01 8.4 LYM285 12734.9 P2.189 6.81E−01 5.1 LYM89 12214.4 B 0.379 3.31E−01 5 LYM24 12064.1 P2.182 6.92E−01 4.8 LYM6 11736.1 B 0.395 3.53E−01 9.5 LYM156 12963.1 P2.138 7.88E−01 2.7 LYM91 13284.3 B 0.486 3.66E−01 34.6 LYM30 11913.4 P2.119 8.02E−01 1.8 LYM88 12193.1 B 0.378 3.74E−01 4.6 LYM26 11821.2 P2.139 8.11E−01 2.7 LYM283 13302.2 B 0.382 3.95E−01 5.8 LYM43 11793.2 P2.119 8.47E−01 1.8 LYM206 12601.2 B 0.447 4.11E−01 23.9 LYM43 11791.5 P2.096 8.52E−01 0.6 LYM91 13284.5 B 0.389 4.14E−01 7.9 LYM103 12712.5 P2.085 9.78E−01 0.1 LYM236 12592.3 B 0.403 4.39E−01 11.7 CONTROL — P2.082 — 0 LYM283 13304.4 B 0.491 4.67E−01 36 LYM289 12492.2 A 92.9471.86E−01 1.4 LYM206 12603.1 B 0.39 4.67E−01 8.1 LYM255 13082.5 A 92.8252.17E−01 1.3 LYM175 12651.2 B 0.442 4.72E−01 22.5 LYM173 12981.6 A93.646 2.22E−01 2.2 LYM73 12623.2 B 0.425 4.91E−01 17.8 LYM106 12144.4 A92.705 3.20E−01 1.2 LYM250 12611.3 B 0.429 4.98E−01 19 LYM212 13032.8 A92.513 3.49E−01 1 LYM206 12603.3 B 0.39 4.98E−01 8.1 LYM102 12222.1 A92.53 3.64E−01 1 LYM159 13352.4 B 0.396 5.08E−01 9.7 LYM61 13171.8 A96.667 3.77E−01 5.5 LYM157 13342.4 B 0.374 5.11E−01 3.6 LYM220 12851.12A 92.99 4.10E−01 1.5 LYM159 13354.5 B 0.412 5.21E−01 14.3 LYM111 12254.3A 92.606 4.40E−01 1.1 LYM99 12243.2 B 0.451 5.34E−01 25.1 LYM287 12771.6A 93.304 4.59E−01 1.8 LYM89 12211.2 B 0.454 5.40E−01 25.9 LYM212 13031.5A 93.614 4.80E−01 2.2 LYM178 12163.4 B 0.388 5.58E−01 7.4 LYM106 12142.2A 92.275 4.86E−01 0.7 LYM129 12573.3 B 0.393 5.67E−01 9 LYM138 12562.2 A92.321 4.89E−01 0.8 LYM178 12164.3 B 0.448 5.70E−01 24.2 LYM119 12461.1A 92.376 4.93E−01 0.8 LYM107 12631.4 B 0.436 5.95E−01 20.9 LYM28812743.8 A 92.288 5.05E−01 0.7 LYM250 12613.2 B 0.381 5.96E−01 5.7 LYM27012871.7 A 92.601 5.14E−01 1.1 LYM178 12161.2 B 0.396 5.98E−01 9.7 LYM18312993.7 A 92.209 5.32E−01 0.6 LYM107 12633.4 B 0.399 6.05E−01 10.7LYM138 12562.1 A 92.298 5.80E−01 0.7 LYM149 12341.1 B 0.438 6.07E−0121.4 LYM212 13031.6 A 92.757 5.96E−01 1.2 LYM149 12344.2 B 0.4467.09E−01 23.7 LYM220 12852.2 A 92.225 6.15E−01 0.7 LYM147 12583.3 B0.389 7.15E−01 7.9 LYM44 11885.4 A 92.076 6.37E−01 0.5 LYM129 12572.4 B0.379 7.22E−01 5.2 LYM111 12251.1 A 92.235 6.39E−01 0.7 LYM88 12191.2 B0.368 7.24E−01 1.9 LYM183 12993.5 A 92.276 6.42E−01 0.7 LYM236 12591.1 B0.37 7.41E−01 2.6 LYM289 12491.1 A 92.318 6.45E−01 0.8 LYM159 13354.8 B0.4 7.62E−01 10.9 LYM242 13053.7 A 92.383 6.48E−01 0.8 LYM147 12583.1 B0.366 7.74E−01 1.5 LYM201 12833.9 A 92.111 6.51E−01 0.5 LYM175 12654.4 B0.376 7.81E−01 4.2 LYM201 12833.7 A 92.164 6.53E−01 0.6 LYM147 12584.5 B0.371 8.02E−01 2.9 LYM242 13051.8 A 92.232 6.65E−01 0.7 LYM256 13324.2 B0.375 8.21E−01 3.9 LYM208 13014.7 A 92.484 6.76E−01 0.9 LYM250 12614.1 B0.371 8.33E−01 2.7 LYM198 13002.8 A 92.042 6.93E−01 0.5 LYM6 11735.1 B0.363 8.97E−01 0.6 LYM153 12323.2 A 91.983 7.00E−01 0.4 LYM91 13283.4 B0.363 9.28E−01 0.6 LYM142 12802.7 A 92.044 7.19E−01 0.5 LYM73 12623.3 B0.367 9.60E−01 1.7 LYM183 12994.8 A 92.015 7.24E−01 0.4 CONTROL — B0.361 — 0 LYM142 12802.9 A 91.961 7.32E−01 0.4 LYM250 12613.4 C 4.5063.98E−04 15.2 LYM61 13174.5 A 92.781 7.51E−01 1.3 LYM206 12601.2 C 4.4631.11E−03 14.1 LYM107 12632.3 A 91.922 7.63E−01 0.3 LYM159 13354.6 C4.331 2.97E−03 10.7 LYM291 12754.9 A 91.875 7.86E−01 0.3 LYM206 12603.3C 4.438 3.26E−03 13.5 LYM201 12833.6 A 93.231 7.98E−01 1.8 LYM73 12623.2C 4.3 4.40E−03 9.9 LYM44 11885.3 A 91.867 8.04E−01 0.3 LYM107 12633.4 C4.356 5.15E−03 11.4 LYM130 12332.1 A 92.065 8.21E−01 0.5 LYM178 12163.3C 4.194 2.03E−02 7.2 LYM137 12153.1 A 91.968 8.65E−01 0.4 LYM250 12613.2C 4.175 3.20E−02 6.7 LYM111 12254.4 A 91.877 8.89E−01 0.3 LYM88 12191.2C 4.375 3.90E−02 11.9 LYM61 13172.4 A 92.025 8.90E−01 0.4 LYM159 13352.4C 4.275 4.86E−02 9.3 LYM100 12134.1 A 91.757 8.94E−01 0.1 LYM91 13284.3C 4.8 6.56E−02 22.7 LYM90 12392.1 A 91.79 9.06E−01 0.2 LYM206 12603.1 C4.2 1.21E−01 7.4 LYM130 12333.1 A 91.91 9.11E−01 0.3 LYM236 12594.3 C4.181 1.21E−01 6.9 LYM197 12824.4 A 91.779 9.37E−01 0.2 LYM178 12161.2 C4.3 1.39E−01 9.9 LYM90 12394.2 A 91.691 9.53E−01 0.1 LYM90 12395.1 C4.163 1.59E−01 6.4 LYM291 12753.6 A 91.669 9.65E−01 0 LYM175 12651.2 C4.538 1.78E−01 16 LYM105 12293.1 A 91.657 9.77E−01 0 LYM99 12243.1 C4.781 1.90E−01 22.2 LYM208 13013.6 A 91.663 9.84E−01 0 LYM157 13342.4 C4.313 2.08E−01 10.3 LYM90 12393.4 A 91.627 9.99E−01 0 LYM236 12592.3 C4.313 2.53E−01 10.3 CONTROL — A 91.624 — 0 LYM236 12591.1 C 4.0752.73E−01 4.2 LYM152 12373.2 B 0.357 1.21E−03 50.4 LYM129 12573.5 C 4.2192.73E−01 7.9 LYM102 12222.1 B 0.386 1.41E−03 62.7 LYM256 13321.2 C 4.1883.23E−01 7.1 LYM174 12411.2 B 0.344 2.44E−03 44.8 LYM6 11735.1 C 4.1443.41E−01 5.9 LYM111 12251.1 B 0.379 3.24E−03 59.8 LYM99 12241.1 C 4.0133.48E−01 2.6 LYM100 12133.3 B 0.349 3.88E−03 47.2 LYM88 12193.1 C 4.1383.66E−01 5.8 LYM106 12144.4 B 0.334 6.10E−03 40.6 LYM6 11736.1 C 4.6383.77E−01 18.6 LYM107 12632.3 B 0.386 6.60E−03 62.7 LYM283 13304.4 C4.569 3.87E−01 16.8 LYM174 12414.3 B 0.324 7.65E−03 36.4 LYM250 12611.3C 4.569 4.20E−01 16.8 LYM102 12222.2 B 0.345 9.57E−03 45.4 LYM12912572.4 C 4.319 4.24E−01 10.4 LYM107 12631.2 B 0.312 1.54E−02 31.4LYM178 12163.4 C 4.266 4.25E−01 9.1 LYM102 12221.2 B 0.336 1.60E−02 41.4LYM147 12583.3 C 4 4.32E−01 2.3 LYM105 12294.3 B 0.313 1.62E−02 31.7LYM250 12614.1 C 4.331 4.39E−01 10.7 LYM143 12524.5 B 0.312 1.76E−0231.4 LYM175 12654.4 C 4.178 4.45E−01 6.8 LYM100 12133.1 B 0.325 1.79E−0236.9 LYM6 11733.2 C 4.113 4.62E−01 5.1 LYM198 13004.6 B 0.319 2.41E−0234.3 LYM159 13354.5 C 4.515 4.68E−01 15.4 LYM137 12153.1 B 0.3052.82E−02 28.5 LYM91 13283.4 C 4.144 4.87E−01 5.9 LYM107 12632.1 B 0.3463.57E−02 45.6 LYM178 12164.3 C 4.481 5.11E−01 14.6 LYM111 12254.4 B0.404 3.60E−02 70.4 LYM283 13302.1 C 4.231 5.82E−01 8.2 LYM105 12297.2 B0.297 4.45E−02 25.1 LYM256 13323.3 C 3.988 6.15E−01 2 LYM137 12151.1 B0.323 4.83E−02 36.1 LYM99 12243.2 C 4.238 6.45E−01 8.3 LYM143 12523.4 B0.293 4.91E−02 23.2 LYM107 12631.4 C 4.1 6.53E−01 4.8 LYM111 12251.3 B0.319 5.49E−02 34.6 LYM178 12164.2 C 4.031 6.82E−01 3.1 LYM106 12142.3 B0.336 5.57E−02 41.4 LYM147 12584.5 C 4.069 6.98E−01 4 LYM220 12851.8 B0.301 5.77E−02 26.9 LYM256 13324.2 C 4.013 7.05E−01 2.6 LYM102 12221.1 B0.299 6.79E−02 26.1 LYM88 12192.1 C 3.988 7.11E−01 2 LYM174 12412.1 B0.384 7.26E−02 61.7 LYM236 12592.4 C 4.138 7.17E−01 5.8 LYM137 12152.1 B0.286 8.50E−02 20.3 LYM89 12211.2 C 4.094 7.24E−01 4.7 LYM137 12154.5 B0.291 8.50E−02 22.4 LYM157 13341.4 C 4.05 7.44E−01 3.5 LYM143 12524.7 B0.289 9.00E−02 21.7 LYM89 12214.4 C 3.956 7.54E−01 1.2 LYM138 12561.3 B0.293 9.03E−02 23.2 LYM86 12181.2 C 3.988 7.84E−01 2 LYM102 12222.3 B0.404 9.03E−02 70.1 LYM73 12622.2 C 4.063 8.04E−01 3.9 LYM142 12804.1 B0.285 9.32E−02 20 LYM149 12344.2 C 4.244 8.12E−01 8.5 LYM105 12293.1 B0.283 1.01E−01 19 LYM159 13354.8 C 4.031 8.41E−01 3.1 LYM107 12631.1 B0.326 1.10E−01 37.5 LYM86 12183.3 C 3.944 8.67E−01 0.8 LYM212 13031.6 B0.284 1.11E−01 19.6 LYM256 13322.3 C 3.925 9.00E−01 0.4 LYM291 12754.9 B0.516 1.24E−01 117.5 LYM283 13302.2 C 3.925 9.20E−01 0.4 LYM105 12297.1B 0.402 1.35E−01 69.3 LYM6 11735.2 C 3.931 9.33E−01 0.5 LYM138 12562.1 B0.278 1.36E−01 17.2 CONTROL — C 3.911 — 0 LYM100 12131.2 B 0.35 1.42E−0147.4 LYM107 12631.4 D 0.286 2.09E−03 30.2 LYM100 12131.3 B 0.3 1.45E−0126.4 LYM236 12592.3 D 0.282 3.12E−03 28.3 LYM289 12491.1 B 0.3481.51E−01 46.7 LYM147 12583.3 D 0.278 7.97E−03 26.3 LYM173 12982.7 B0.326 1.56E−01 37.5 LYM129 12572.4 D 0.27 9.42E−03 22.7 LYM106 12144.3 B0.351 1.59E−01 48 LYM6 11736.1 D 0.268 1.07E−02 22.1 LYM174 12414.2 B0.384 1.60E−01 61.7 LYM178 12163.4 D 0.283 1.31E−02 28.9 LYM107 12633.4B 0.372 1.75E−01 56.7 LYM89 12211.4 D 0.269 3.53E−02 22.3 LYM212 13032.8B 0.304 1.89E−01 28.2 LYM73 12623.2 D 0.254 4.68E−02 15.5 LYM153 12324.2B 0.271 1.90E−01 14.3 LYM90 12395.3 D 0.285 6.11E−02 29.5 LYM143 12521.1B 0.303 1.91E−01 27.5 LYM99 12243.2 D 0.263 6.21E−02 19.6 LYM138 12561.1B 0.319 1.91E−01 34.3 LYM88 12193.1 D 0.288 6.59E−02 30.9 LYM100 12134.1B 0.298 1.91E−01 25.6 LYM206 12603.1 D 0.271 6.76E−02 23.2 LYM15212371.3 B 0.311 2.03E−01 30.9 LYM250 12613.2 D 0.251 6.95E−02 14.5LYM289 12493.2 B 0.281 2.03E−01 18.5 LYM90 12392.1 D 0.249 7.55E−02 13.5LYM106 12142.2 B 0.451 2.04E−01 89.9 LYM86 12182.3 D 0.247 9.53E−02 12.5LYM106 12141.4 B 0.427 2.09E−01 79.9 LYM90 12395.1 D 0.278 1.03E−01 26.4LYM173 12982.6 B 0.34 2.21E−01 43.3 LYM147 12584.4 D 0.244 1.25E−01 11.2LYM107 12631.4 B 0.503 2.37E−01 112.1 LYM178 12161.2 D 0.268 1.42E−0122.2 LYM137 12151.4 B 0.337 2.43E−01 41.9 LYM236 12594.3 D 0.2451.49E−01 11.3 LYM288 12744.7 B 0.319 2.48E−01 34.3 LYM128 12641.3 D0.243 1.63E−01 10.8 LYM153 12324.1 B 0.376 2.54E−01 58.3 LYM178 12164.3D 0.242 1.63E−01 10.3 LYM111 12254.3 B 0.275 2.65E−01 15.9 LYM20612603.3 D 0.345 1.82E−01 57 LYM197 12824.4 B 0.34 2.66E−01 43.4 LYM15913354.6 D 0.257 1.95E−01 16.9 LYM102 12222.6 B 0.528 2.70E−01 122.3LYM73 12623.1 D 0.247 2.14E−01 12.5 LYM152 12371.2 B 0.323 2.76E−01 35.9LYM159 13354.5 D 0.241 2.20E−01 9.8 LYM220 12851.12 B 0.266 2.76E−0111.9 LYM129 12573.3 D 0.267 2.33E−01 21.4 LYM138 12566.1 B 0.2962.78E−01 24.6 LYM250 12613.4 D 0.326 2.36E−01 48.2 LYM198 13002.6 B0.401 2.91E−01 68.8 LYM107 12633.4 D 0.321 2.54E−01 45.9 LYM173 12981.5B 0.268 2.98E−01 13 LYM88 12191.2 D 0.285 2.57E−01 29.6 LYM142 12802.9 B0.323 3.06E−01 36.1 LYM175 12651.2 D 0.241 2.65E−01 9.5 LYM44 11884.1 B0.263 3.14E−01 10.6 LYM6 11735.1 D 0.298 2.86E−01 35.7 LYM143 12521.2 B0.265 3.27E−01 11.7 LYM250 12614.1 D 0.24 2.88E−01 9.2 LYM152 12372.2 B0.284 3.43E−01 19.7 LYM157 13341.4 D 0.235 3.14E−01 7.1 LYM288 12743.9 B0.381 3.52E−01 60.6 LYM178 12163.3 D 0.274 3.28E−01 24.7 LYM173 12981.6B 0.327 3.64E−01 37.7 LYM99 12243.1 D 0.298 3.29E−01 35.7 LYM111 12252.2B 0.409 3.69E−01 72.2 LYM88 12194.2 D 0.242 3.37E−01 10 LYM111 12251.4 B0.336 3.76E−01 41.7 LYM129 12573.5 D 0.286 3.40E−01 30 LYM289 12491.4 B0.356 3.78E−01 50.1 LYM86 12183.3 D 0.235 3.42E−01 6.9 LYM198 13002.8 B0.276 3.80E−01 16.1 LYM89 12214.2 D 0.283 3.49E−01 29 LYM119 12463.2 B0.336 3.81E−01 41.4 LYM206 12601.2 D 0.332 3.68E−01 51 LYM105 12294.2 B0.309 3.82E−01 30.3 LYM128 12642.3 D 0.254 4.14E−01 15.4 LYM255 13082.5B 0.268 3.92E−01 12.7 LYM91 13284.3 D 0.257 4.24E−01 16.8 LYM142 12803.6B 0.426 3.92E−01 79.3 LYM236 12591.1 D 0.27 4.45E−01 23 LYM105 12295.2 B0.326 3.98E−01 37.5 LYM91 13283.1 D 0.231 4.60E−01 5 LYM208 13013.6 B0.359 4.05E−01 51.2 LYM89 12214.3 D 0.256 4.88E−01 16.3 LYM242 13051.8 B0.312 4.11E−01 31.4 LYM206 12601.3 D 0.232 5.03E−01 5.4 LYM183 12991.7 B0.258 4.18E−01 8.5 LYM86 12183.1 D 0.245 5.08E−01 11.6 LYM119 12461.1 B0.27 4.22E−01 13.8 LYM236 12592.4 D 0.269 5.38E−01 22.2 LYM142 12801.8 B0.258 4.22E−01 8.8 LYM175 12654.4 D 0.262 5.39E−01 19 LYM288 12743.8 B0.269 4.37E−01 13.5 LYM90 12393.1 D 0.251 5.42E−01 14.3 LYM287 12773.7 B0.303 4.38E−01 27.5 LYM250 12614.2 D 0.243 5.44E−01 10.5 LYM212 13031.5B 0.266 4.43E−01 11.9 LYM250 12611.3 D 0.265 5.54E−01 20.5 LYM25513082.7 B 0.264 4.46E−01 11.4 LYM283 13304.4 D 0.251 6.17E−01 14.1LYM143 12524.2 B 0.309 4.52E−01 30.3 LYM6 11733.2 D 0.235 6.79E−01 6.8LYM153 12321.2 B 0.303 4.54E−01 27.5 LYM147 12584.5 D 0.227 6.93E−01 3.3LYM270 12871.7 B 0.264 4.64E−01 11.1 LYM157 13342.4 D 0.249 7.01E−0113.2 LYM208 13012.8 B 0.349 4.64E−01 46.9 LYM91 13283.4 D 0.248 7.12E−0112.8 LYM220 12851.11 B 0.273 4.64E−01 15 LYM128 12641.1 D 0.236 7.33E−017.6 LYM255 13082.9 B 0.327 4.69E−01 37.7 LYM206 12603.2 D 0.225 7.44E−012.4 LYM152 12373.1 B 0.256 4.76E−01 8 LYM73 12622.2 D 0.234 8.40E−01 6.4LYM174 12411.3 B 0.265 4.89E−01 11.7 LYM175 12654.6 D 0.226 8.63E−01 2.7LYM173 12981.8 B 0.254 4.95E−01 7 LYM159 13352.4 D 0.225 8.63E−01 2.3LYM288 12741.9 B 0.268 5.10E−01 12.7 LYM147 12583.1 D 0.235 8.75E−01 7.2LYM270 12871.5 B 0.262 5.13E−01 10.5 LYM178 12164.2 D 0.226 8.77E−01 3LYM44 11885.4 B 0.281 5.16E−01 18.5 LYM88 12191.1 D 0.225 9.11E−01 2.2LYM119 12462.2 B 0.361 5.34E−01 52.2 LYM89 12214.4 D 0.221 9.16E−01 0.7LYM130 12332.2 B 0.275 5.42E−01 15.9 LYM149 12344.2 D 0.227 9.29E−01 3.5LYM212 13034.9 B 0.256 5.42E−01 8 LYM147 12581.4 D 0.223 9.55E−01 1.6LYM142 12804.3 B 0.259 5.43E−01 93 LYM175 12651.4 D 0.222 9.80E−01 1LYM197 12824.7 B 0.293 5.46E−01 23.2 CONTROL — D 0.22 — 0 LYM22012851.13 B 0.262 5.67E−01 10.3 LYM107 12633.4 E 9.188 1.23E−03 8.4LYM198 13002.5 B 0.282 5.80E−01 18.8 LYM206 12603.3 E 9.188 1.23E−03 8.4LYM137 12151.2 B 0.252 5.93E−01 6.1 LYM88 12193.1 E 9.063 3.77E−03 6.9LYM183 12993.7 B 0.277 6.04E−01 16.7 LYM6 11734.3 E 9.125 2.59E−02 7.7LYM212 13034.8 B 0.294 6.34E−01 23.8 LYM157 13341.4 E 8.813 4.79E−02 4LYM220 12852.2 B 0.261 6.54E−01 10.1 LYM283 13304.4 E 8.813 4.79E−02 4LYM130 12331.3 B 0.284 6.60E−01 19.6 LYM178 12164.3 E 8.875 9.63E−02 4.7LYM288 12744.6 B 0.258 6.65E−01 8.8 LYM90 12393.1 E 9.063 1.17E−01 6.9LYM291 12753.6 B 0.249 6.65E−01 5.1 LYM90 12395.1 E 9.125 1.79E−01 7.7LYM138 12564.1 B 0.259 6.70E−01 9 LYM250 12613.4 E 8.688 1.79E−01 2.5LYM289 12492.2 B 0.263 6.79E−01 10.6 LYM99 12243.2 E 8.688 1.79E−01 2.5LYM201 12833.7 B 0.281 6.89E−01 18.5 LYM107 12631.4 E 8.75 2.07E−01 3.2LYM130 12334.1 B 0.247 7.13E−01 4 LYM73 12623.2 E 8.75 2.07E−01 3.2LYM138 12562.2 B 0.252 7.28E−01 6.1 LYM90 12395.3 E 9.188 3.34E−01 8.4LYM142 12802.7 B 0.246 7.38E−01 3.5 LYM147 12583.3 E 8.688 4.46E−01 2.5LYM130 12333.1 B 0.257 7.42E−01 8.2 LYM250 12614.1 E 8.688 4.46E−01 2.5LYM153 12323.2 B 0.255 7.44E−01 7.4 LYM128 12642.3 E 8.625 4.56E−01 1.8LYM106 12142.1 B 0.262 7.70E−01 10.3 LYM129 12573.3 E 8.625 4.56E−01 1.8LYM270 12872.5 B 0.244 7.99E−01 2.7 LYM88 12191.2 E 8.625 4.56E−01 1.8LYM183 12994.7 B 0.243 8.20E−01 2.4 LYM89 12211.4 E 8.625 4.56E−01 1.8LYM242 13053.7 B 0.242 8.52E−01 1.9 LYM99 12243.1 E 8.625 4.56E−01 1.8LYM183 12994.8 B 0.243 8.58E−01 2.2 LYM206 12603.1 E 8.563 5.62E−01 1LYM291 12751.7 B 0.243 8.65E−01 2.4 LYM6 11733.2 E 8.563 5.62E−01 1LYM287 12771.6 B 0.241 8.75E−01 1.6 LYM86 12182.3 E 8.563 5.62E−01 1LYM44 11884.3 B 0.246 9.08E−01 3.8 LYM6 11735.1 E 8.813 5.79E−01 4LYM270 12872.7 B 0.245 9.08E−01 3.2 LYM236 12591.1 E 8.75 5.95E−01 3.2LYM255 13081.5 B 0.244 9.17E−01 3 LYM73 12623.1 E 8.75 5.95E−01 3.2LYM270 12871.8 B 0.238 9.96E−01 0.1 LYM178 12163.3 E 8.688 6.19E−01 2.5CONTROL — B 0.237 — 0 LYM147 12584.4 E 8.563 7.37E−01 1 LYM102 12221.2 C3.181 7.20E−05 59.4 LYM91 13283.1 E 8.563 8.30E−01 1 LYM174 12411.2 C3.1 1.24E−04 55.4 LYM236 12594.3 E 8.625 8.51E−01 1.8 LYM111 12254.4 C3.5 1.46E−04 75.4 LYM250 12613.2 E 8.5 8.55E−01 0.3 LYM137 12151.1 C3.044 1.55E−04 52.5 LYM128 12641.3 E 8.5 8.98E−01 0.3 LYM102 12222.2 C3.031 2.15E−04 51.9 LYM206 12601.2 E 8.5 8.98E−01 0.3 LYM198 13004.6 C2.969 2.68E−04 48.8 LYM236 12592.3 E 8.5 8.98E−01 0.3 LYM106 12144.4 C2.881 4.76E−04 44.4 LYM159 13354.5 E 8.521 9.20E−01 0.5 LYM174 12414.3 C2.856 5.73E−04 43.1 LYM129 12572.4 E 8.5 9.40E−01 0.3 LYM152 12373.2 C2.856 6.33E−04 43.1 LYM175 12653.3 E 8.5 9.40E−01 0.3 LYM105 12297.2 C2.869 7.57E−04 43.8 LYM178 12164.2 E 8.5 9.40E−01 0.3 LYM137 12152.1 C2.731 1.65E−03 36.9 LYM99 12241.1 E 8.5 9.40E−01 0.3 LYM100 12134.1 C2.881 1.87E−03 44.4 LYM157 13342.4 E 8.5 9.59E−01 0.3 LYM107 12632.1 C2.913 2.19E−03 46 CONTROL — E 8.475 — 0 LYM105 12294.3 C 2.8 2.39E−0340.3 LYM206 12603.3 F 0.579 5.70E−05 43 LYM107 12631.1 C 2.688 2.68E−0334.7 LYM236 12592.3 F 0.487 6.32E−03 20.3 LYM107 12632.3 C 3.3 3.16E−0365.4 LYM73 12623.1 F 0.442 1.25E−01 9.2 LYM107 12631.2 C 2.681 6.82E−0334.4 LYM129 12572.4 F 0.442 1.62E−01 9.1 LYM100 12133.3 C 3.294 7.28E−0365.1 LYM73 12623.2 F 0.438 1.80E−01 8 LYM197 12824.4 C 2.738 9.52E−0337.2 LYM159 13354.6 F 0.443 1.85E−01 9.4 LYM106 12141.4 C 3.675 1.04E−0284.2 LYM206 12603.1 F 0.456 1.88E−01 12.6 LYM152 12373.1 C 2.5 1.15E−0225.3 LYM250 12613.4 F 0.533 2.23E−01 31.6 LYM143 12523.4 C 2.5561.22E−02 28.1 LYM147 12583.3 F 0.434 2.25E−01 7.1 LYM111 12251.1 C 3.5251.30E−02 76.7 LYM90 12395.3 F 0.432 2.54E−01 6.6 LYM291 12754.9 C 4.0311.90E−02 102 LYM90 12395.1 F 0.459 2.58E−01 13.2 LYM142 12804.1 C 2.4942.73E−02 25 LYM178 12163.4 F 0.487 2.76E−01 20.2 LYM102 12221.1 C 2.8133.28E−02 41 LYM89 12211.4 F 0.433 2.87E−01 7 LYM288 12744.7 C 2.6383.46E−02 32.2 LYM250 12614.1 F 0.429 3.05E−01 5.8 LYM100 12131.2 C 3.1543.50E−02 58 LYM107 12633.4 F 0.487 3.08E−01 20.2 LYM111 12254.3 C 2.5633.71E−02 28.4 LYM236 12591.1 F 0.481 3.14E−01 18.8 LYM105 12297.1 C3.269 4.57E−02 63.8 LYM88 12193.1 F 0.49 3.39E−01 20.9 LYM212 13031.5 C2.354 4.66E−02 18 LYM236 12594.3 F 0.46 3.51E−01 13.6 LYM183 12991.7 C2.456 4.75E−02 23.1 LYM99 12243.1 F 0.496 3.78E−01 22.5 LYM102 12222.1 C3.556 5.16E−02 78.2 LYM6 11735.1 F 0.482 4.20E−01 19.1 LYM143 12524.5 C2.756 5.74E−02 38.1 LYM178 12161.2 F 0.465 4.22E−01 14.9 LYM102 12222.3C 3.769 6.05E−02 88.9 LYM250 12614.2 F 0.452 4.40E−01 11.5 LYM10512293.1 C 2.419 6.23E−02 21.2 LYM157 13341.4 F 0.435 4.48E−01 7.4 LYM27012871.5 C 2.321 6.49E−02 16.3 LYM175 12654.4 F 0.472 4.48E−01 16.5LYM153 12324.2 C 2.313 7.05E−02 15.9 LYM129 12573.5 F 0.457 4.50E−0112.9 LYM100 12133.1 C 3.288 7.40E−02 64.8 LYM206 12603.2 F 0.4224.75E−01 4.3 LYM106 12142.3 C 3.038 8.14E−02 52.2 LYM128 12641.1 F 0.4244.85E−01 4.7 LYM152 12372.2 C 2.605 9.07E−02 30.6 LYM178 12163.3 F 0.4414.99E−01 8.9 LYM174 12414.2 C 3.1 9.40E−02 55.4 LYM206 12601.2 F 0.55.39E−01 23.5 LYM174 12412.1 C 3.269 1.06E−01 63.8 LYM88 12191.2 F 0.4466.11E−01 10.2 LYM106 12144.3 C 2.813 1.07E−01 41 LYM159 13354.5 F 0.4167.19E−01 2.8 LYM270 12872.5 C 2.375 1.14E−01 19 LYM129 12573.3 F 0.4187.51E−01 3.1 LYM138 12566.1 C 2.838 1.14E−01 42.2 LYM89 12214.3 F 0.4128.15E−01 1.7 LYM138 12561.3 C 2.619 1.21E−01 31.2 LYM89 12214.2 F 0.4228.16E−01 4.1 LYM173 12981.8 C 2.263 1.25E−01 13.4 LYM283 13304.4 F 0.428.23E−01 3.8 LYM289 12491.1 C 2.9 1.26E−01 45.3 LYM236 12592.4 F 0.4258.29E−01 5 LYM143 12521.1 C 2.613 1.32E−01 30.9 LYM250 12611.3 F 0.4168.42E−01 2.7 LYM173 12982.6 C 2.863 1.34E−01 43.5 LYM107 12631.4 F 0.4099.12E−01 0.9 LYM212 13032.8 C 2.438 1.36E−01 22.2 LYM90 12393.1 F 0.4119.45E−01 1.4 LYM138 12562.1 C 2.569 1.40E−01 28.7 LYM159 13352.4 F 0.4079.49E−01 0.4 LYM212 13034.9 C 2.244 1.40E−01 12.5 LYM91 13284.3 F 0.419.52E−01 1.2 LYM106 12142.2 C 3.731 1.41E−01 87 LYM91 13283.4 F 0.4119.54E−01 1.4 LYM153 12324.1 C 2.831 1.48E−01 41.9 CONTROL — F 0.405 — 0LYM100 12131.3 C 2.856 1.54E−01 43.1 LYM6 11734.3 G 9.53 2.63E−01 9.9LYM107 12631.4 C 4.221 1.57E−01 111.6 LYM206 12603.3 G 9.772 3.62E−0112.7 LYM289 12493.2 C 2.231 1.58E−01 11.8 LYM236 12591.1 G 9.1574.16E−01 5.6 LYM152 12371.2 C 2.731 1.62E−01 36.9 LYM99 12243.1 G 9.0964.92E−01 4.9 LYM220 12851.8 C 2.8 1.62E−01 40.3 LYM206 12601.2 G 9.115.79E−01 5 LYM220 12851.12 C 2.244 1.69E−01 12.5 LYM250 12614.2 G 8.9056.05E−01 2.7 LYM138 12561.1 C 3.119 1.71E−01 56.3 LYM159 13354.5 G 8.8456.87E−01 2 LYM137 12151.2 C 2.288 1.75E−01 14.6 LYM236 12592.3 G 9.0138.02E−01 3.9 LYM142 12802.9 C 2.738 1.81E−01 37.2 LYM175 12654.4 G 8.9748.11E−01 3.5 LYM111 12252.2 C 3.175 2.04E−01 59.1 LYM250 12613.4 G 8.9138.18E−01 2.8 LYM102 12222.6 C 4.188 2.20E−01 109.9 LYM91 13284.4 G 8.8778.65E−01 2.4 LYM142 12801.8 C 2.194 2.26E−01 9.9 LYM206 12603.1 G 8.758.71E−01 0.9 LYM105 12294.2 C 2.725 2.36E−01 36.6 LYM6 11733.2 G 8.8918.75E−01 2.5 LYM288 12743.9 C 2.644 2.36E−01 32.5 LYM147 12584.4 G 8.7479.59E−01 0.9 LYM107 12633.4 C 2.969 2.38E−01 48.8 LYM175 12651.4 G 8.7489.72E−01 0.9 LYM111 12251.3 C 2.938 2.59E−01 47.2 LYM175 12654.6 G 8.6979.75E−01 0.3 LYM143 12524.7 C 2.369 2.68E−01 18.7 CONTROL — G 8.673 — 0LYM220 12852.4 C 2.194 2.78E−01 9.9 LYM107 12631.4 H 14.158 3.91E−0335.7 LYM198 13002.6 C 3.356 2.79E−01 68.2 LYM147 12583.3 H 13.5348.52E−03 29.7 LYM208 13012.8 C 2.65 2.79E−01 32.8 LYM236 12592.3 H13.487 9.09E−03 29.3 LYM288 12743.8 C 2.356 2.80E−01 18.1 LYM90 12395.1H 13.78 1.94E−02 32.1 LYM173 12982.7 C 2.725 2.82E−01 36.6 LYM12912572.4 H 12.866 2.83E−02 23.3 LYM289 12491.4 C 2.775 2.83E−01 39.1LYM206 12603.1 H 13.405 4.09E−02 28.5 LYM119 12463.2 C 2.894 2.84E−01 45LYM147 12584.4 H 12.629 4.40E−02 21 LYM90 12392.1 C 2.475 2.89E−01 24LYM88 12194.2 H 12.515 4.87E−02 20 LYM137 12153.1 C 2.588 2.97E−01 29.7LYM6 11736.1 H 12.391 5.69E−02 18.8 LYM288 12741.9 C 2.319 2.97E−01 16.2LYM89 12211.4 H 12.771 6.74E−02 22.4 LYM220 12852.2 C 2.269 3.14E−0113.7 LYM90 12395.3 H 14.316 6.99E−02 37.2 LYM142 12803.6 C 3.2633.16E−01 63.5 LYM73 12623.2 H 12.201 8.98E−02 16.9 LYM287 12773.7 C2.469 3.34E−01 23.7 LYM86 12182.3 H 12.123 9.17E−02 16.2 LYM143 12521.2C 2.225 3.47E−01 11.5 LYM128 12641.3 H 12.249 1.00E−01 17.4 LYM15212371.3 C 2.625 3.48E−01 31.6 LYM206 12603.3 H 17.874 1.01E−01 71.3LYM212 13031.6 C 2.469 3.77E−01 23.7 LYM99 12243.2 H 12.41 1.03E−01 18.9LYM173 12981.6 C 2.475 3.79E−01 24 LYM178 12163.4 H 12.811 1.54E−01 22.8LYM255 13082.7 C 2.169 3.81E−01 8.7 LYM159 13354.6 H 12.193 1.55E−0116.9 LYM105 12295.2 C 2.844 3.99E−01 42.5 LYM236 12594.3 H 11.8841.59E−01 13.9 LYM137 12151.4 C 3.006 4.08E−01 50.7 LYM88 12193.1 H14.778 1.60E−01 41.6 LYM119 12461.1 C 2.281 4.10E−01 14.3 LYM178 12164.3H 12.031 1.81E−01 15.3 LYM198 13002.5 C 2.619 4.15E−01 31.2 LYM25012614.1 H 12.094 2.04E−01 15.9 LYM111 12251.4 C 3.275 4.15E−01 64.1LYM250 12613.4 H 16.068 2.07E−01 54 LYM138 12564.1 C 2.263 4.26E−01 13.4LYM250 12613.2 H 11.628 2.09E−01 11.5 LYM208 13013.6 C 2.819 4.34E−0141.3 LYM73 12623.1 H 12.001 2.10E−01 15 LYM183 12994.8 C 2.256 4.45E−0113.1 LYM88 12191.2 H 13.605 2.15E−01 30.4 LYM153 12321.2 C 2.6384.50E−01 32.2 LYM99 12243.1 H 14.765 2.34E−01 41.5 LYM143 12524.2 C2.519 4.55E−01 26.2 LYM107 12633.4 H 15.436 2.76E−01 47.9 LYM289 12492.2C 2.481 4.61E−01 24.4 LYM178 12163.3 H 13.589 2.92E−01 30.2 LYM24213051.8 C 2.406 4.75E−01 20.6 LYM6 11735.1 H 15.004 3.12E−01 43.8 LYM18312994.7 C 2.431 4.77E−01 21.8 LYM178 12161.2 H 12.57 3.13E−01 20.5LYM255 13082.5 C 2.163 4.79E−01 8.4 LYM128 12642.3 H 12.501 3.37E−0119.8 LYM287 12771.6 C 2.231 4.83E−01 11.8 LYM129 12573.3 H 12.9313.61E−01 23.9 LYM173 12981.5 C 2.331 4.84E−01 16.8 LYM206 12601.2 H17.033 3.65E−01 63.2 LYM288 12744.6 C 2.206 4.86E−01 10.6 LYM129 12573.5H 13.692 3.66E−01 31.2 LYM220 12851.11 C 2.229 5.02E−01 11.7 LYM8912214.2 H 13.553 4.00E−01 29.9 LYM291 12751.7 C 2.206 5.06E−01 10.6LYM175 12651.2 H 11.266 4.15E−01 8 LYM255 13082.9 C 2.394 5.08E−01 20LYM6 11734.3 H 11.461 4.19E−01 9.8 LYM220 12851.13 C 2.175 5.17E−01 9LYM90 12392.1 H 11.166 4.25E−01 7 LYM291 12753.6 C 2.225 5.20E−01 11.5LYM236 12591.1 H 13.166 4.56E−01 26.2 LYM44 11884.1 C 2.15 5.32E−01 7.8LYM157 13341.4 H 11.131 4.73E−01 6.7 LYM130 12332.2 C 2.219 5.39E−0111.2 LYM90 12393.1 H 12.601 4.83E−01 20.8 LYM197 12824.7 C 2.6255.42E−01 31.6 LYM89 12214.3 H 12.181 5.09E−01 16.7 LYM119 12462.2 C2.925 5.45E−01 46.6 LYM250 12614.2 H 11.889 5.16E−01 14 LYM242 13053.7 C2.094 5.53E−01 4.9 LYM91 13284.3 H 11.762 5.45E−01 12.7 LYM44 11885.4 C2.35 5.71E−01 17.8 LYM283 13304.4 H 12.329 5.80E−01 18.2 LYM137 12154.5C 2.319 5.87E−01 16.2 LYM86 12183.1 H 11.569 5.87E−01 10.9 LYM13012331.3 C 2.5 6.12E−01 25.3 LYM236 12592.4 H 12.52 5.99E−01 20 LYM14212804.3 C 2.156 6.19E−01 8.1 LYM6 11733.2 H 11.309 6.05E−01 8.4 LYM27012871.7 C 2.2 6.64E−01 10.3 LYM250 12611.3 H 12.099 6.19E−01 16 LYM17412411.3 C 2.15 6.66E−01 7.8 LYM175 12654.6 H 11.242 6.78E−01 7.7 LYM18312993.7 C 2.225 6.77E−01 11.5 LYM175 12654.4 H 12.126 6.86E−01 16.2LYM138 12562.2 C 2.181 6.86E−01 9.3 LYM206 12603.2 H 10.774 7.04E−01 3.3LYM212 13034.8 C 2.313 6.90E−01 15.9 LYM128 12641.1 H 11.41 7.15E−01 9.4LYM270 12872.7 C 2.169 7.14E−01 8.7 LYM91 13283.4 H 11.798 7.22E−01 13.1LYM130 12333.1 C 2.294 7.33E−01 15 LYM147 12584.5 H 10.733 7.53E−01 2.9LYM153 12323.2 C 2.188 7.44E−01 9.6 LYM206 12601.3 H 10.704 7.86E−01 2.6LYM106 12142.1 C 2.363 7.50E−01 18.4 LYM157 13342.4 H 11.448 7.87E−019.7 LYM130 12334.1 C 2.05 7.51E−01 2.7 LYM147 12583.1 H 11.545 8.28E−0110.7 LYM198 13002.8 C 2.213 7.61E−01 10.9 LYM86 12183.3 H 10.6568.33E−01 2.1 LYM287 12771.7 C 2.063 8.00E−01 3.4 LYM178 12164.2 H 10.8388.72E−01 3.9 LYM44 11882.1 C 2.106 8.42E−01 5.6 LYM91 13283.1 H 10.5149.28E−01 0.8 LYM198 13005.6 C 2.063 8.64E−01 3.4 LYM73 12622.2 H 10.7589.28E−01 3.1 LYM291 12751.2 C 2.042 8.80E−01 2.3 LYM149 12344.2 H 10.7649.42E−01 3.2 LYM201 12833.7 C 2.088 8.82E−01 4.6 CONTROL — H 10.434 — 0LYM44 11884.3 C 2.069 9.05E−01 3.7 LYM206 12603.3 J 0.042 2.32E−03 61.6LYM44 11885.3 C 2.013 9.12E−01 0.9 LYM250 12613.4 J 0.038 1.29E−02 47.8LYM90 12394.2 C 2.006 9.59E−01 0.5 LYM206 12601.2 J 0.039 2.60E−02 48.5LYM255 13082.8 C 2 9.86E−01 0.2 LYM107 12633.4 J 0.037 2.93E−02 43.3CONTROL — C 1.995 — 0 LYM6 11735.1 J 0.035 4.68E−02 36.2 LYM102 12222.2D 0.265 6.00E−06 40 LYM99 12243.1 J 0.035 5.89E−02 35.2 LYM288 12743.9 D0.264 1.70E−05 39.2 LYM88 12191.2 J 0.035 6.27E−02 32.8 LYM173 12981.6 D0.248 9.60E−05 31 LYM129 12573.5 J 0.035 7.06E−02 33.1 LYM138 12561.3 D0.31 1.04E−04 63.6 LYM236 12592.3 J 0.034 7.96E−02 30.2 LYM107 12631.4 D0.239 1.13E−04 26.3 LYM89 12214.2 J 0.034 8.48E−02 31.2 LYM105 12297.2 D0.24 2.13E−04 26.7 LYM90 12395.3 J 0.033 8.93E−02 28.3 LYM130 12332.1 D0.283 2.74E−03 49.6 LYM129 12572.4 J 0.033 1.15E−01 27.1 LYM289 12493.1D 0.272 3.81E−03 43.6 LYM178 12163.4 J 0.033 1.22E−01 25.9 LYM13012334.1 D 0.23 4.39E−03 21.6 LYM147 12583.3 J 0.033 1.28E−01 25.3 LYM10212222.1 D 0.228 5.99E−03 20.7 LYM236 12592.4 J 0.033 1.43E−01 28.1LYM255 13082.8 D 0.252 6.25E−03 33.3 LYM107 12631.4 J 0.032 1.44E−0124.3 LYM106 12144.4 D 0.258 6.35E−03 36.4 LYM89 12211.4 J 0.032 1.56E−0123.7 LYM107 12631.2 D 0.216 6.37E−03 14.2 LYM6 11736.1 J 0.032 1.66E−0124.2 LYM153 12323.2 D 0.282 7.68E−03 49 LYM90 12395.1 J 0.032 1.73E−0122.4 LYM105 12293.1 D 0.278 1.12E−02 47 LYM88 12193.1 J 0.032 1.92E−0121.6 LYM201 12833.7 D 0.212 1.16E−02 12.1 LYM250 12611.3 J 0.0321.97E−01 24.5 LYM119 12461.4 D 0.301 1.22E−02 59 LYM236 12591.1 J 0.0322.14E−01 22.8 LYM287 12771.6 D 0.219 1.38E−02 15.5 LYM99 12243.2 J 0.0312.28E−01 20.1 LYM105 12294.2 D 0.248 1.47E−02 31.1 LYM178 12161.2 J0.031 2.32E−01 20.1 LYM173 12982.6 D 0.215 1.80E−02 13.7 LYM178 12163.3J 0.031 2.45E−01 20 LYM137 12153.1 D 0.227 2.52E−02 19.8 LYM206 12603.1J 0.031 2.53E−01 19 LYM152 12373.1 D 0.234 2.75E−02 23.5 LYM159 13354.6J 0.031 2.78E−01 18.6 LYM270 12873.6 D 0.252 2.79E−02 33.2 LYM12912573.3 J 0.031 2.87E−01 18.4 LYM138 12561.1 D 0.399 4.37E−02 110.9LYM175 12654.4 J 0.031 2.90E−01 19.4 LYM287 12774.6 D 0.206 4.37E−02 8.8LYM90 12392.1 J 0.03 3.06E−01 16.4 LYM242 13052.5 D 0.212 4.61E−02 12.1LYM91 13284.3 J 0.031 3.18E−01 17.4 LYM137 12151.4 D 0.27 5.04E−02 42.4LYM159 13354.5 J 0.03 3.56E−01 15.4 LYM100 12133.3 D 0.205 5.59E−02 8.1LYM89 12214.3 J 0.03 3.58E−01 15.8 LYM137 12151.2 D 0.25 6.45E−02 32.1LYM250 12613.2 J 0.03 3.76E−01 14.5 LYM289 12492.2 D 0.246 6.50E−02 29.9LYM236 12594.3 J 0.029 4.45E−01 12.5 LYM174 12414.3 D 0.32 7.11E−02 69LYM157 13342.4 J 0.03 4.61E−01 14 LYM153 12322.1 D 0.218 7.32E−02 15.3LYM91 13283.4 J 0.029 4.75E−01 13.2 LYM111 12254.4 D 0.23 7.53E−02 21.3LYM73 12623.2 J 0.029 4.77E−01 11.7 LYM119 12463.2 D 0.302 7.64E−02 59.5LYM175 12651.2 J 0.029 4.79E−01 11.9 LYM106 12142.2 D 0.307 7.80E−0262.1 LYM6 11733.2 J 0.029 4.88E−01 11.9 LYM153 12324.2 D 0.27 7.86E−0242.8 LYM86 12182.3 J 0.029 4.94E−01 11 LYM106 12141.4 D 0.219 7.93E−0215.7 LYM283 13304.4 J 0.029 5.17E−01 11.3 LYM212 13032.8 D 0.2398.15E−02 26.2 LYM90 12393.1 J 0.029 5.43E−01 10.3 LYM119 12461.1 D 0.3088.59E−02 62.9 LYM73 12623.1 J 0.029 5.45E−01 9.8 LYM201 12833.9 D 0.2038.86E−02 7.2 LYM128 12642.3 J 0.029 5.62E−01 9.5 LYM100 12131.3 D 0.2099.17E−02 10.3 LYM73 12622.2 J 0.029 5.64E−01 10.5 LYM288 12743.8 D 0.2369.25E−02 24.6 LYM250 12614.2 J 0.028 5.82E−01 9.3 LYM220 12851.8 D 0.2869.36E−02 51.1 LYM86 12183.1 J 0.028 6.07E−01 8.6 LYM102 12222.3 D 0.2291.07E−01 20.9 LYM86 12183.3 J 0.028 6.17E−01 8.1 LYM105 12295.2 D 0.2691.09E−01 41.9 LYM91 13283.1 J 0.028 6.19E−01 8 LYM174 12411.2 D 0.2761.10E−01 45.9 LYM250 12614.1 J 0.028 6.33E−01 7.7 LYM289 12491.1 D 0.2011.29E−01 6.1 LYM157 13341.4 J 0.028 6.74E−01 7.2 LYM137 12151.1 D 0.2531.36E−01 33.5 LYM178 12164.3 J 0.028 6.96E−01 6.2 LYM138 12562.2 D 0.2461.48E−01 29.8 LYM128 12641.1 J 0.028 6.98E−01 6.8 LYM107 12632.3 D 0.2981.51E−01 57.5 LYM147 12584.4 J 0.028 7.13E−01 5.8 LYM105 12294.3 D 0.2261.59E−01 19.4 LYM175 12651.4 J 0.028 7.62E−01 5.8 LYM119 12462.1 D 0.2781.80E−01 47 LYM159 13352.4 J 0.027 7.80E−01 4.6 LYM153 12324.1 D 0.2831.89E−01 49.3 LYM88 12194.2 J 0.027 7.86E−01 4.4 LYM288 12743.5 D 0.2741.92E−01 44.7 LYM175 12654.6 J 0.027 8.01E−01 4.3 LYM174 12412.1 D 0.2822.01E−01 48.9 LYM147 12583.1 J 0.027 8.50E−01 3.7 LYM212 13031.6 D 0.2112.07E−01 11.6 LYM149 12344.2 J 0.027 8.67E−01 3.2 LYM197 12821.6 D 0.2242.15E−01 18.1 LYM128 12641.3 J 0.027 8.88E−01 2.2 LYM107 12631.1 D 0.2252.32E−01 18.8 LYM88 12191.1 J 0.027 9.00E−01 2.1 LYM90 12395.3 D 0.232.34E−01 21.4 LYM206 12601.3 J 0.027 9.12E−01 1.8 LYM242 13051.8 D 0.2232.35E−01 17.6 LYM89 12214.4 J 0.026 9.25E−01 1.5 LYM173 12981.5 D 0.2272.35E−01 19.7 LYM147 12584.5 J 0.026 9.58E−01 0.9 LYM130 12332.2 D 0.2462.46E−01 29.8 LYM178 12164.2 J 0.026 9.69E−01 0.6 LYM111 12251.1 D 0.2032.49E−01 7.1 LYM147 12581.4 J 0.026 9.95E−01 0.1 LYM174 12411.3 D 0.2992.57E−01 57.9 CONTROL — J 0.026 — 0 LYM198 13005.8 D 0.2 2.58E−01 5.8LYM157 13341.4 K 0.697 6.89E−02 22.1 LYM119 12462.2 D 0.25 2.82E−01 32LYM88 12193.1 K 0.617 4.88E−01 8.1 LYM153 12321.2 D 0.235 2.89E−01 24.2LYM73 12623.2 K 0.605 6.11E−01 6 LYM111 12252.2 D 0.239 2.92E−01 26.1LYM107 12633.4 K 0.604 6.16E−01 5.8 LYM242 13053.7 D 0.215 3.07E−01 13.4LYM159 13354.8 K 0.603 6.36E−01 5.6 LYM102 12221.1 D 0.221 3.09E−01 16.5LYM90 12395.3 K 0.6 6.64E−01 5.1 LYM255 13082.9 D 0.22 3.26E−01 16LYM175 12654.6 K 0.6 6.86E−01 5.2 LYM255 13082.5 D 0.28 3.38E−01 47.9LYM90 12393.2 K 0.596 7.01E−01 4.4 LYM142 12802.9 D 0.23 3.43E−01 21.4LYM206 12603.3 K 0.597 7.01E−01 4.6 LYM288 12741.9 D 0.229 3.44E−01 21.2LYM250 12613.4 K 0.595 7.13E−01 4.2 LYM106 12144.3 D 0.24 3.50E−01 26.6LYM129 12572.4 K 0.594 7.18E−01 4.1 LYM152 12371.2 D 0.281 3.62E−01 48.6LYM6 11734.3 K 0.594 7.26E−01 4.1 LYM255 13082.7 D 0.252 3.81E−01 32.9LYM157 13342.4 K 0.594 7.43E−01 4.1 LYM106 12142.3 D 0.208 3.88E−01 9.9LYM159 13351.1 K 0.592 7.73E−01 3.7 LYM138 12564.1 D 0.231 4.04E−01 22LYM90 12395.1 K 0.586 8.23E−01 2.6 LYM289 12493.2 D 0.254 4.06E−01 34.4LYM159 13354.5 K 0.587 8.28E−01 2.9 LYM152 12371.3 D 0.233 4.09E−01 22.8LYM90 12393.1 K 0.586 8.34E−01 2.6 LYM107 12632.1 D 0.218 4.39E−01 14.9LYM99 12243.1 K 0.582 8.78E−01 1.9 LYM291 12754.9 D 0.24 4.58E−01 26.9LYM236 12591.1 K 0.581 8.85E−01 1.8 LYM201 12834.6 D 0.21 4.77E−01 10.8LYM99 12241.1 K 0.578 9.22E−01 1.2 LYM102 12222.6 D 0.215 5.01E−01 13.5LYM6 11733.2 K 0.577 9.25E−01 1.1 LYM183 12994.8 D 0.233 5.40E−01 23.1CONTROL — K 0.571 — 0 LYM291 12753.6 D 0.211 5.42E−01 11.2 LYM20612603.3 L 2.303 1.34E−03 74.3 LYM130 12331.3 D 0.242 5.46E−01 27.6LYM250 12613.4 L 2.054 9.93E−03 55.4 LYM287 12771.7 D 0.2 5.49E−01 5.6LYM206 12601.2 L 2.137 1.29E−02 61.7 LYM289 12491.4 D 0.196 5.53E−01 3.5LYM107 12633.4 L 1.947 3.16E−02 47.3 LYM130 12333.1 D 0.213 5.99E−0112.3 LYM6 11735.1 L 1.898 4.09E−02 43.6 LYM143 12524.7 D 0.231 6.05E−0121.8 LYM99 12243.1 L 1.861 4.63E−02 40.8 LYM137 12154.5 D 0.23 6.26E−0121.2 LYM88 12193.1 L 1.806 6.33E−02 36.6 LYM111 12251.4 D 0.196 6.28E−013.4 LYM90 12395.3 L 1.794 6.59E−02 35.8 LYM183 12993.7 D 0.205 6.65E−018.1 LYM107 12631.4 L 1.733 1.04E−01 31.1 LYM183 12993.5 D 0.205 6.71E−018.2 LYM88 12191.2 L 1.733 1.17E−01 31.1 LYM287 12773.7 D 0.205 6.87E−018.5 LYM129 12573.5 L 1.749 1.18E−01 32.3 LYM270 12871.5 D 0.22 7.04E−0115.9 LYM236 12592.3 L 1.724 1.21E−01 30.4 LYM142 12801.8 D 0.1967.32E−01 3.7 LYM90 12395.1 L 1.708 1.26E−01 29.2 LYM143 12524.5 D 0.2147.37E−01 13.1 LYM147 12583.3 L 1.696 1.38E−01 28.3 LYM270 12871.7 D0.197 7.40E−01 3.8 LYM89 12214.2 L 1.715 1.44E−01 29.8 LYM173 12981.8 D0.2 7.60E−01 5.4 LYM129 12572.4 L 1.663 1.82E−01 25.9 LYM44 11885.4 D0.199 7.63E−01 5.2 LYM178 12163.3 L 1.667 1.88E−01 26.2 LYM208 13012.5 D0.209 7.67E−01 10.3 LYM206 12603.1 L 1.65 1.92E−01 24.8 LYM143 12521.1 D0.192 7.71E−01 1.2 LYM236 12591.1 L 1.661 2.18E−01 25.7 LYM212 13034.9 D0.211 7.93E−01 11.3 LYM89 12211.4 L 1.61 2.51E−01 21.8 LYM173 12982.7 D0.205 8.10E−01 8.3 LYM236 12592.4 L 1.624 2.79E−01 22.9 LYM198 13004.6 D0.191 8.26E−01 1 LYM129 12573.3 L 1.602 2.85E−01 21.2 LYM142 12804.3 D0.198 8.80E−01 4.7 LYM178 12163.4 L 1.579 3.05E−01 19.5 LYM255 13081.5 D0.197 8.86E−01 4.2 LYM6 11736.1 L 1.579 3.15E−01 19.5 LYM197 12822.7 D0.196 8.90E−01 3.2 LYM99 12243.2 L 1.562 3.36E−01 18.2 LYM270 12871.8 D0.196 9.09E−01 3.3 LYM147 12584.4 L 1.547 3.54E−01 17.1 LYM270 12872.7 D0.193 9.10E−01 2 LYM159 13354.6 L 1.558 3.54E−01 17.9 LYM174 12414.2 D0.19 9.23E−01 0.4 LYM178 12161.2 L 1.556 3.55E−01 17.7 LYM111 12251.3 D0.19 9.75E−01 0.3 LYM90 12393.1 L 1.561 3.57E−01 18.1 LYM105 12297.1 D0.19 9.79E−01 0.4 LYM88 12194.2 L 1.546 3.63E−01 17 LYM183 12994.7 D0.19 9.91E−01 0.1 LYM250 12611.3 L 1.546 4.06E−01 17 CONTROL — D 0.189 —0 LYM128 12642.3 L 1.524 4.21E−01 15.3 LYM138 12561.1 E 9 2.20E−03 10.8LYM283 13304.4 L 1.532 4.27E−01 15.9 LYM130 12332.1 E 8.938 3.29E−03 10LYM175 12654.4 L 1.544 4.29E−01 16.8 LYM119 12461.4 E 9 7.75E−03 10.8LYM73 12623.2 L 1.52 4.29E−01 15 LYM130 12334.1 E 9 7.75E−03 10.8 LYM25012614.1 L 1.516 4.32E−01 14.7 LYM153 12323.2 E 9 7.75E−03 10.8 LYM8912214.3 L 1.523 4.32E−01 15.2 LYM174 12412.1 E 8.625 3.12E−02 6.2 LYM8612182.3 L 1.51 4.46E−01 14.2 LYM255 13082.8 E 8.75 3.12E−02 7.7 LYM7312623.1 L 1.498 4.75E−01 13.3 LYM255 13082.7 E 8.563 5.65E−02 5.4 LYM17812164.3 L 1.489 4.93E−01 12.7 LYM130 12332.2 E 9 9.08E−02 10.8 LYM25012614.2 L 1.499 4.94E−01 13.4 LYM119 12461.1 E 8.688 1.11E−01 6.9 LYM23612594.3 L 1.49 5.02E−01 12.7 LYM220 12851.8 E 8.875 1.21E−01 9.2 LYM9113284.3 L 1.492 5.06E−01 12.9 LYM153 12324.1 E 9.063 1.37E−01 11.5 LYM9113283.4 L 1.495 5.25E−01 13.1 LYM174 12414.3 E 9.063 1.37E−01 11.5LYM128 12641.3 L 1.468 5.48E−01 11.1 LYM106 12141.4 E 8.5 1.45E−01 4.6LYM6 11733.2 L 1.459 5.91E−01 10.4 LYM287 12771.6 E 8.5 1.45E−01 4.6LYM250 12613.2 L 1.454 5.93E−01 10 LYM105 12297.2 E 8.75 1.65E−01 7.7LYM175 12651.2 L 1.452 6.05E−01 9.9 LYM107 12631.4 E 8.545 1.71E−01 5.2LYM175 12654.6 L 1.452 6.13E−01 9.9 LYM105 12295.2 E 8.563 1.84E−01 5.4LYM157 13342.4 L 1.454 6.29E−01 10 LYM107 12631.2 E 8.563 1.84E−01 5.4LYM128 12641.1 L 1.446 6.33E−01 9.4 LYM111 12252.2 E 8.563 1.84E−01 5.4LYM86 12183.1 L 1.432 6.61E−01 8.4 LYM143 12524.7 E 8.375 2.21E−01 3.1LYM157 13341.4 L 1.432 6.63E−01 8.3 LYM289 12493.2 E 8.875 2.51E−01 9.2LYM147 12583.1 L 1.431 7.05E−01 8.2 LYM137 12153.1 E 8.688 2.75E−01 6.9LYM90 12392.1 L 1.406 7.24E−01 6.4 LYM152 12371.2 E 8.375 3.07E−01 3.1LYM6 11734.3 L 1.405 7.36E−01 6.3 LYM289 12491.1 E 8.375 3.07E−01 3.1LYM73 12622.2 L 1.402 7.68E−01 6.1 LYM138 12562.2 E 8.438 3.12E−01 3.8LYM206 12603.2 L 1.361 8.74E−01 3 LYM291 12754.9 E 8.438 3.12E−01 3.8LYM91 13283.1 L 1.343 9.30E−01 1.6 LYM119 12462.1 E 8.813 3.33E−01 8.5LYM149 12344.2 L 1.342 9.41E−01 1.6 LYM102 12222.6 E 8.5 3.37E−01 4.6LYM178 12164.2 L 1.337 9.51E−01 1.2 LYM174 12411.3 E 8.5 3.37E−01 4.6LYM86 12183.3 L 1.33 9.73E−01 0.6 LYM288 12741.9 E 8.875 3.53E−01 9.2LYM159 13352.4 L 1.33 9.74E−01 0.6 LYM111 12254.4 E 8.313 3.67E−01 2.3CONTROL — L 1.322 — 0 LYM119 12462.2 E 8.813 4.24E−01 8.5 LYM206 12603.3M 0.288 1.32E−03 69.7 LYM137 12154.5 E 8.625 4.90E−01 6.2 LYM250 12613.4M 0.257 1.04E−02 51.3 LYM137 12151.2 E 8.688 4.92E−01 6.9 LYM206 12601.2M 0.267 1.40E−02 57.5 LYM138 12561.3 E 8.813 4.94E−01 8.5 LYM107 12633.4M 0.243 3.48E−02 43.4 LYM174 12411.2 E 8.313 5.23E−01 2.3 LYM6 11735.1 M0.237 4.53E−02 39.8 LYM288 12743.9 E 8.313 5.23E−01 2.3 LYM99 12243.1 M0.233 5.12E−02 37.1 LYM119 12463.2 E 8.563 5.75E−01 5.4 LYM88 12193.1 M0.226 7.05E−02 33.1 LYM289 12493.1 E 8.563 5.75E−01 5.4 LYM90 12395.3 M0.224 7.35E−02 32.2 LYM106 12144.4 E 8.5 5.87E−01 4.6 LYM107 12631.4 M0.217 1.17E−01 27.7 LYM102 12222.3 E 8.25 5.97E−01 1.5 LYM88 12191.2 M0.217 1.33E−01 27.6 LYM242 13051.8 E 8.25 5.97E−01 1.5 LYM129 12573.5 M0.219 1.34E−01 28.8 LYM137 12151.1 E 8.625 6.24E−01 6.2 LYM236 12592.3 M0.215 1.38E−01 27 LYM130 12331.3 E 8.375 7.06E−01 3.1 LYM90 12395.1 M0.214 1.44E−01 25.9 LYM242 13052.5 E 8.25 7.22E−01 1.5 LYM147 12583.3 M0.212 1.57E−01 24.9 LYM289 12491.4 E 8.25 7.22E−01 1.5 LYM89 12214.2 M0.214 1.65E−01 26.3 LYM44 11885.4 E 8.25 7.22E−01 1.5 LYM178 12163.4 M0.21 1.72E−01 24 LYM106 12144.3 E 8.375 7.96E−01 3.1 LYM129 12572.4 M0.208 2.08E−01 22.6 LYM106 12142.2 E 8.25 8.01E−01 1.5 LYM178 12163.3 M0.208 2.16E−01 22.8 LYM138 12564.1 E 8.25 8.01E−01 1.5 LYM206 12603.1 M0.206 2.21E−01 21.5 LYM183 12993.7 E 8.25 8.01E−01 1.5 LYM236 12591.1 M0.208 2.50E−01 22.4 LYM255 13082.5 E 8.25 8.01E−01 1.5 LYM89 12211.4 M0.201 2.90E−01 18.6 LYM288 12743.8 E 8.25 8.01E−01 1.5 LYM175 12654.4 M0.203 3.08E−01 19.7 LYM102 12222.2 E 8.188 8.26E−01 0.8 LYM236 12592.4 M0.203 3.19E−01 19.7 LYM270 12873.6 E 8.188 8.26E−01 0.8 LYM129 12573.3 M0.2 3.27E−01 18 LYM288 12743.5 E 8.313 8.56E−01 2.3 LYM6 11736.1 M 0.1973.63E−01 16.4 LYM143 12524.5 E 8.25 8.96E−01 1.5 LYM99 12243.2 M 0.1953.88E−01 15.1 LYM288 12744.6 E 8.188 9.43E−01 0.8 LYM159 13354.6 M 0.1954.08E−01 14.8 CONTROL — E 8.125 — 0 LYM147 12584.4 M 0.193 4.09E−01 14LYM138 12561.3 F 0.52 2.90E−05 66 LYM178 12161.2 M 0.194 4.10E−01 14.6LYM289 12493.1 F 0.53 4.10E−05 69.3 LYM90 12393.1 M 0.195 4.11E−01 15LYM153 12323.2 F 0.486 1.01E−04 55.1 LYM88 12194.2 M 0.193 4.20E−01 13.9LYM255 13082.8 F 0.465 2.39E−04 48.5 LYM250 12611.3 M 0.193 4.65E−0113.9 LYM119 12463.2 F 0.468 2.41E−04 49.5 LYM128 12642.3 M 0.19 4.85E−0112.3 LYM137 12151.1 F 0.46 2.99E−04 46.9 LYM283 13304.4 M 0.192 4.90E−0112.9 LYM107 12631.4 F 0.458 3.34E−04 46.1 LYM73 12623.2 M 0.19 4.95E−0112 LYM153 12324.2 F 0.455 3.98E−04 45.1 LYM89 12214.3 M 0.19 4.97E−0112.2 LYM137 12151.4 F 0.483 5.10E−04 54.3 LYM250 12614.1 M 0.1894.99E−01 11.7 LYM105 12293.1 F 0.448 5.60E−04 42.9 LYM86 12182.3 M 0.1895.15E−01 11.2 LYM119 12462.1 F 0.474 1.01E−03 51.2 LYM73 12623.1 M 0.1875.48E−01 10.4 LYM102 12222.3 F 0.432 1.14E−03 38 LYM250 12614.2 M 0.1875.67E−01 10.4 LYM105 12297.2 F 0.429 1.36E−03 37 LYM178 12164.3 M 0.1865.69E−01 9.7 LYM102 12221.1 F 0.424 1.85E−03 35.5 LYM236 12594.3 M 0.1865.78E−01 9.8 LYM288 12743.9 F 0.434 1.86E−03 38.6 LYM91 13284.3 M 0.1875.80E−01 10 LYM138 12562.2 F 0.407 4.58E−03 29.8 LYM91 13283.4 M 0.1875.98E−01 10.1 LYM153 12321.2 F 0.4 6.82E−03 27.8 LYM128 12641.3 M 0.1846.31E−01 8.2 LYM102 12222.2 F 0.421 7.13E−03 34.3 LYM6 11733.2 M 0.1826.76E−01 7.5 LYM107 12631.1 F 0.398 9.15E−03 27.1 LYM250 12613.2 M 0.1826.80E−01 7.1 LYM119 12461.1 F 0.454 9.42E−03 44.9 LYM175 12651.2 M 0.1816.92E−01 7 LYM174 12412.1 F 0.52 1.39E−02 66 LYM175 12654.6 M 0.1817.00E−01 7 LYM130 12332.2 F 0.401 1.60E−02 27.9 LYM157 13342.4 M 0.1827.13E−01 7.1 LYM100 12133.3 F 0.382 2.01E−02 21.9 LYM128 12641.1 M 0.1817.21E−01 6.5 LYM137 12153.1 F 0.397 2.03E−02 26.8 LYM86 12183.1 M 0.1797.55E−01 5.5 LYM173 12982.6 F 0.398 2.07E−02 26.9 LYM157 13341.4 M 0.1797.57E−01 5.5 LYM102 12222.6 F 0.381 2.15E−02 21.6 LYM159 13354.5 M 0.1787.87E−01 4.8 LYM288 12743.5 F 0.483 2.36E−02 54.1 LYM147 12583.1 M 0.1797.91E−01 5.4 LYM242 13051.8 F 0.389 2.77E−02 24.2 LYM90 12392.1 M 0.1768.29E−01 3.6 LYM174 12414.2 F 0.374 3.39E−02 19.4 LYM6 11734.3 M 0.1768.39E−01 3.5 LYM143 12521.1 F 0.395 3.46E−02 26 LYM73 12622.2 M 0.1758.64E−01 3.3 LYM287 12771.6 F 0.374 3.57E−02 19.3 LYM206 12603.2 M 0.179.89E−01 0.2 LYM105 12295.2 F 0.409 3.81E−02 30.5 CONTROL — M 0.17 — 0LYM198 13005.8 F 0.392 4.29E−02 25.3 LYM206 12603.3 N 0.249 2.57E−0231.4 LYM106 12142.3 F 0.369 4.67E−02 17.7 LYM250 12613.4 N 0.24 5.39E−0227 LYM212 13031.6 F 0.403 5.15E−02 28.7 LYM107 12633.4 N 0.239 8.02E−0226.2 LYM130 12334.1 F 0.401 5.54E−02 28.1 LYM88 12191.2 N 0.231 1.01E−0122.1 LYM130 12332.1 F 0.481 5.69E−02 53.6 LYM6 11735.1 N 0.23 1.18E−0121.4 LYM289 12493.2 F 0.411 5.77E−02 31.1 LYM206 12601.2 N 0.2361.28E−01 24.9 LYM107 12632.1 F 0.388 6.16E−02 23.7 LYM236 12592.3 N0.225 1.46E−01 19.1 LYM44 11882.1 F 0.365 6.29E−02 16.4 LYM236 12592.4 N0.228 1.67E−01 20.7 LYM197 12821.6 F 0.432 7.71E−02 37.7 LYM129 12573.5N 0.222 2.12E−01 17.1 LYM138 12561.1 F 0.557 7.77E−02 77.9 LYM99 12243.1N 0.221 2.18E−01 16.8 LYM201 12834.6 F 0.39 7.85E−02 24.4 LYM250 12611.3N 0.222 2.41E−01 17.3 LYM173 12981.8 F 0.375 8.92E−02 19.8 LYM15913354.5 N 0.218 2.47E−01 15.2 LYM111 12254.4 F 0.375 9.07E−02 19.8LYM157 13341.4 N 0.216 2.84E−01 14.2 LYM174 12411.2 F 0.4 9.19E−02 27.8LYM91 13284.3 N 0.218 2.91E−01 15.2 LYM174 12414.3 F 0.483 9.49E−02 54.1LYM89 12211.4 N 0.211 3.54E−01 11.7 LYM100 12131.3 F 0.459 9.57E−02 46.4LYM129 12572.4 N 0.211 3.67E−01 11.3 LYM242 13052.5 F 0.357 9.97E−02 14LYM159 13354.6 N 0.21 3.95E−01 11 LYM107 12632.3 F 0.491 1.05E−01 56.9LYM90 12395.3 N 0.209 4.04E−01 10.4 LYM111 12251.4 F 0.356 1.07E−01 13.6LYM178 12161.2 N 0.21 4.14E−01 10.9 LYM111 12252.2 F 0.483 1.09E−01 54.1LYM73 12623.2 N 0.209 4.32E−01 10.2 LYM106 12141.4 F 0.416 1.12E−01 32.8LYM236 12591.1 N 0.211 4.35E−01 11.3 LYM173 12981.6 F 0.387 1.14E−0123.6 LYM206 12603.1 N 0.209 4.38E−01 10.3 LYM105 12294.3 F 0.3561.20E−01 13.5 LYM178 12163.4 N 0.208 4.45E−01 9.8 LYM119 12461.4 F 0.5391.23E−01 71.9 LYM6 11736.1 N 0.208 4.50E−01 9.8 LYM152 12373.1 F 0.3981.26E−01 27.1 LYM99 12243.2 N 0.207 4.52E−01 9.6 LYM255 13082.9 F 0.4131.28E−01 31.9 LYM89 12214.2 N 0.208 4.71E−01 10.1 LYM107 12633.4 F 0.3641.38E−01 16.1 LYM236 12594.3 N 0.206 5.03E−01 8.7 LYM287 12774.6 F 0.3721.44E−01 18.9 LYM88 12193.1 N 0.206 5.05E−01 8.7 LYM255 13082.7 F 0.5241.53E−01 67.3 LYM178 12163.3 N 0.206 5.07E−01 8.9 LYM289 12491.4 F 0.3721.56E−01 18.7 LYM175 12654.4 N 0.206 5.32E−01 9 LYM242 13054.9 F 0.351.59E−01 11.6 LYM175 12651.2 N 0.205 5.44E−01 8.2 LYM153 12322.1 F 0.4371.73E−01 39.4 LYM73 12622.2 N 0.207 5.48E−01 9.2 LYM106 12144.4 F 0.4191.77E−01 33.6 LYM90 12392.1 N 0.203 5.60E−01 7.2 LYM106 12144.3 F 0.4171.79E−01 33.2 LYM129 12573.3 N 0.204 5.70E−01 7.8 LYM105 12294.2 F 0.3941.86E−01 25.9 LYM250 12614.2 N 0.203 5.87E−01 7.2 LYM143 12524.2 F 0.3632.01E−01 15.8 LYM147 12583.3 N 0.202 5.92E−01 6.9 LYM119 12462.2 F 0.4972.05E−01 58.5 LYM91 13283.4 N 0.204 5.95E−01 7.7 LYM152 12371.2 F 0.4482.08E−01 42.9 LYM90 12395.1 N 0.202 6.07E−01 6.6 LYM153 12324.1 F 0.4962.14E−01 58.4 LYM6 11733.2 N 0.201 6.29E−01 6.3 LYM137 12151.2 F 0.4292.24E−01 36.8 LYM250 12613.2 N 0.201 6.31E−01 6.1 LYM201 12833.9 F 0.3562.26E−01 13.5 LYM159 13352.4 N 0.201 6.42E−01 6.1 LYM137 12154.5 F 0.4592.29E−01 44.6 LYM157 13342.4 N 0.202 6.50E−01 6.9 LYM270 12872.7 F 0.3422.46E−01 9.3 LYM6 11734.3 N 0.2 6.63E−01 5.5 LYM174 12411.3 F 0.4842.50E−01 54.5 LYM175 12651.4 N 0.198 7.57E−01 4.9 LYM242 13053.7 F 0.3512.53E−01 12 LYM107 12631.4 N 0.196 7.70E−01 3.7 LYM270 12873.6 F 0.442.56E−01 40.5 LYM89 12214.3 N 0.193 8.96E−01 1.7 LYM138 12564.1 F 0.4552.60E−01 45.3 LYM283 13304.4 N 0.192 9.03E−01 1.7 LYM270 12872.5 F 0.3412.66E−01 8.9 LYM88 12194.2 N 0.191 9.26E−01 1.2 LYM111 12251.3 F 0.3552.73E−01 13.4 LYM90 12393.1 N 0.192 9.27E−01 1.2 LYM102 12222.1 F 0.3882.84E−01 23.7 LYM73 12623.1 N 0.191 9.45E−01 0.9 LYM255 13082.5 F 0.4662.88E−01 48.6 LYM175 12654.6 N 0.191 9.48E−01 0.9 LYM100 12134.1 F 0.3493.08E−01 11.4 LYM256 13323.3 N 0.19 9.77E−01 0.4 LYM143 12524.7 F 0.4383.10E−01 39.9 LYM128 12641.1 N 0.19 9.78E−01 0.4 LYM152 12371.3 F 0.3653.10E−01 16.5 CONTROL — N 0.189 — 0 LYM291 12753.6 F 0.338 3.10E−01 8LYM107 12631.4 O 1.77 3.57E−03 32.1 LYM183 12994.8 F 0.422 3.14E−01 34.8LYM178 12163.4 O 1.708 5.93E−03 27.5 LYM44 11885.4 F 0.339 3.19E−01 8.1LYM147 12583.3 O 1.692 7.49E−03 26.3 LYM220 12851.8 F 0.468 3.32E−0149.4 LYM236 12592.3 O 1.686 7.99E−03 25.9 LYM142 12804.1 F 0.4083.37E−01 30.4 LYM90 12395.1 O 1.723 2.51E−02 28.6 LYM288 12741.9 F 0.4423.47E−01 41 LYM129 12572.4 O 1.608 3.01E−02 20.1 LYM107 12631.2 F 0.3773.60E−01 20.3 LYM147 12584.4 O 1.579 4.98E−02 17.9 LYM130 12331.3 F0.438 3.65E−01 39.9 LYM206 12603.1 O 1.676 5.34E−02 25.1 LYM197 12821.11F 0.351 3.71E−01 12.1 LYM88 12194.2 O 1.564 5.43E−02 16.8 LYM183 12994.7F 0.388 3.71E−01 23.9 LYM6 11736.1 O 1.549 6.34E−02 15.6 LYM90 12395.3 F0.433 3.94E−01 38.2 LYM89 12211.4 O 1.596 8.59E−02 19.2 LYM255 13081.5 F0.38 3.98E−01 21.4 LYM90 12395.3 O 1.789 8.97E−02 33.6 LYM287 12771.7 F0.349 4.04E−01 11.3 LYM86 12182.3 O 1.515 1.09E−01 13.1 LYM288 12744.6 F0.399 4.10E−01 27.3 LYM73 12623.2 O 1.525 1.09E−01 13.9 LYM143 12524.5 F0.395 4.19E−01 26 LYM206 12603.3 O 2.234 1.15E−01 66.8 LYM289 12491.1 F0.333 4.32E−01 6.2 LYM128 12641.3 O 1.531 1.26E−01 14.3 LYM173 12981.5 F0.398 4.35E−01 27.1 LYM99 12243.2 O 1.551 1.32E−01 15.8 LYM106 12142.2 F0.413 4.38E−01 31.7 LYM88 12193.1 O 1.847 1.84E−01 37.9 LYM137 12152.1 F0.391 4.50E−01 24.8 LYM159 13354.6 O 1.524 1.99E−01 13.8 LYM143 12521.2F 0.346 4.92E−01 10.4 LYM236 12594.3 O 1.486 2.04E−01 10.9 LYM19813004.6 F 0.339 5.17E−01 8.1 LYM250 12613.4 O 2.009 2.25E−01 49.9 LYM27012871.8 F 0.36 5.27E−01 15 LYM178 12164.3 O 1.504 2.35E−01 12.3 LYM15212372.2 F 0.364 5.34E−01 16.1 LYM88 12191.2 O 1.701 2.49E−01 27 LYM20813012.5 F 0.399 5.44E−01 27.4 LYM99 12243.1 O 1.846 2.59E−01 37.8 LYM20813013.6 F 0.353 5.52E−01 12.6 LYM250 12614.1 O 1.512 2.61E−01 12.9LYM130 12333.1 F 0.372 5.61E−01 18.7 LYM73 12623.1 O 1.5 2.71E−01 12LYM142 12801.8 F 0.327 5.89E−01 4.3 LYM250 12613.2 O 1.454 2.72E−01 8.5LYM291 12751.2 F 0.336 5.96E−01 7.2 LYM107 12633.4 O 1.93 2.97E−01 44.1LYM242 13051.9 F 0.361 5.96E−01 15.1 LYM178 12163.3 O 1.699 3.27E−0126.8 LYM212 13032.8 F 0.338 6.12E−01 7.9 LYM6 11735.1 O 1.875 3.35E−0140 LYM289 12492.2 F 0.332 6.33E−01 5.8 LYM178 12161.2 O 1.571 3.67E−0117.3 LYM270 12871.5 F 0.368 6.53E−01 17.3 LYM206 12601.2 O 2.1293.80E−01 58.9 LYM183 12993.7 F 0.357 6.81E−01 13.9 LYM128 12642.3 O1.563 3.92E−01 16.7 LYM100 12133.1 F 0.343 6.89E−01 9.6 LYM129 12573.5 O1.711 3.99E−01 27.8 LYM111 12251.1 F 0.33 6.90E−01 5.5 LYM129 12573.3 O1.616 4.06E−01 20.7 LYM288 12743.8 F 0.363 7.05E−01 15.8 LYM89 12214.2 O1.694 4.34E−01 26.5 LYM61 13174.7 F 0.336 7.42E−01 7.2 LYM236 12591.1 O1.646 4.95E−01 22.9 LYM291 12754.9 F 0.35 7.44E−01 11.8 LYM6 11734.3 O1.433 5.31E−01 7 LYM138 12566.1 F 0.352 7.57E−01 12.5 LYM90 12393.1 O1.575 5.32E−01 17.6 LYM197 12824.7 F 0.332 7.58E−01 5.8 LYM175 12651.2 O1.408 5.50E−01 5.1 LYM212 13034.9 F 0.338 7.64E−01 7.9 LYM175 12654.4 O1.596 5.60E−01 19.1 LYM287 12773.7 F 0.337 7.64E−01 7.6 LYM89 12214.3 O1.523 5.70E−01 13.7 LYM198 13002.6 F 0.328 7.83E−01 4.8 LYM90 12392.1 O1.396 5.76E−01 4.2 LYM198 13002.5 F 0.337 8.11E−01 7.5 LYM250 12614.2 O1.486 5.89E−01 11 LYM102 12221.2 F 0.32 8.28E−01 2.3 LYM91 13284.3 O1.47 6.23E−01 9.8 LYM201 12831.5 F 0.326 8.38E−01 4.1 LYM283 13304.4 O1.541 6.30E−01 15.1 LYM183 12993.5 F 0.32 8.80E−01 2.1 LYM157 13341.4 O1.391 6.32E−01 3.9 LYM142 12802.9 F 0.319 8.84E−01 1.9 LYM236 12592.4 O1.565 6.43E−01 16.8 LYM142 12804.3 F 0.332 8.91E−01 5.8 LYM86 12183.1 O1.446 6.73E−01 8 LYM201 12833.7 F 0.32 9.02E−01 2.3 LYM250 12611.3 O1.512 6.74E−01 12.9 LYM105 12297.1 F 0.322 9.11E−01 2.7 LYM6 11733.2 O1.414 7.15E−01 5.5 LYM208 13011.6 F 0.325 9.20E−01 3.8 LYM91 13283.4 O1.475 7.75E−01 10.1 LYM198 13005.6 F 0.316 9.23E−01 0.9 LYM175 12654.6 O1.405 7.80E−01 4.9 LYM197 12822.7 F 0.316 9.30E−01 0.7 LYM128 12641.1 O1.426 7.91E−01 6.5 LYM173 12982.7 F 0.32 9.33E−01 2.1 LYM159 13354.5 O1.365 8.31E−01 1.9 LYM270 12871.7 F 0.315 9.39E−01 0.6 LYM157 13342.4 O1.431 8.44E−01 6.8 LYM208 13012.8 F 0.317 9.44E−01 1.2 LYM147 12583.1 O1.443 8.70E−01 7.7 LYM143 12523.4 F 0.317 9.74E−01 1.3 LYM206 12603.2 O1.347 9.41E−01 0.5 LYM90 12392.1 F 0.315 9.85E−01 0.4 LYM178 12164.2 O1.355 9.61E−01 1.1 LYM291 12751.7 F 0.313 9.97E−01 0 LYM147 12584.5 O1.342 9.84E−01 0.2 CONTROL — F 0.313 — 0 LYM73 12622.2 O 1.345 9.91E−010.4 LYM137 12154.5 G 9.652 2.50E−03 28.4 LYM149 12344.2 O 1.346 9.92E−010.5 LYM100 12131.3 G 9.793 2.50E−03 30.3 CONTROL — O 1.339 — 0 LYM13812566.1 G 9.6 3.03E−03 27.8 LYM178 12163.4 P 2.405 5.91E−03 17 LYM19712821.6 G 9.487 4.52E−03 26.3 LYM236 12592.3 P 2.371 7.03E−03 15.4LYM288 12744.6 G 10.091 4.70E−03 34.3 LYM90 12395.3 P 2.356 1.03E−0214.6 LYM153 12324.2 G 9.399 5.04E−03 25.1 LYM88 12193.1 P 2.445 2.73E−0219 LYM174 12412.1 G 9.898 6.17E−03 31.7 LYM89 12211.4 P 2.286 3.08E−0211.2 LYM288 12743.9 G 9.309 6.49E−03 23.9 LYM147 12583.3 P 2.3213.39E−02 12.9 LYM143 12524.7 G 9.948 7.18E−03 32.4 LYM206 12603.3 P 2.673.75E−02 29.9 LYM174 12411.3 G 8.938 1.97E−02 18.9 LYM206 12603.1 P2.365 4.22E−02 15 LYM143 12524.5 G 9.436 2.22E−02 25.6 LYM159 13354.6 P2.244 6.96E−02 9.2 LYM138 12561.1 G 8.803 2.93E−02 17.1 LYM73 12623.2 P2.228 8.37E−02 8.4 LYM174 12414.3 G 9.918 3.00E−02 32 LYM99 12243.2 P2.217 9.87E−02 7.8 LYM102 12222.3 G 8.786 3.08E−02 16.9 LYM90 12395.1 P2.348 1.12E−01 14.2 LYM242 13052.5 G 8.763 3.35E−02 16.6 LYM6 11735.1 P2.459 1.30E−01 19.6 LYM105 12295.2 G 8.76 3.42E−02 16.6 LYM147 12584.4 P2.197 1.35E−01 6.9 LYM255 13082.9 G 9.044 3.44E−02 20.4 LYM88 12194.2 P2.194 1.52E−01 6.8 LYM289 12491.4 G 8.796 3.65E−02 17.1 LYM107 12631.4 P2.302 1.87E−01 12 LYM102 12221.2 G 9.395 3.66E−02 25 LYM6 11734.3 P2.255 1.95E−01 9.7 LYM100 12131.2 G 8.713 3.84E−02 15.9 LYM6 11736.1 P2.175 1.97E−01 5.8 LYM153 12321.2 G 9.902 4.76E−02 31.8 LYM73 12623.1 P2.201 2.31E−01 7.1 LYM137 12151.4 G 8.637 4.92E−02 14.9 LYM236 12594.3 P2.181 2.39E−01 6.1 LYM90 12395.1 G 8.672 4.94E−02 15.4 LYM250 12613.4 P2.573 2.42E−01 25.2 LYM137 12152.1 G 9.49 5.11E−02 26.3 LYM178 12161.2 P2.337 2.59E−01 13.7 LYM107 12631.1 G 9.234 5.21E−02 22.9 LYM107 12633.4P 2.571 2.61E−01 25.1 LYM289 12493.1 G 11.018 5.29E−02 46.6 LYM17812163.3 P 2.335 2.65E−01 13.6 LYM183 12994.7 G 8.609 5.68E−02 14.6LYM129 12572.4 P 2.18 2.78E−01 6.1 LYM153 12323.2 G 8.693 6.46E−02 15.7LYM250 12613.2 P 2.186 2.87E−01 6.3 LYM106 12142.1 G 8.737 6.51E−02 16.3LYM86 12182.3 P 2.149 3.06E−01 4.5 LYM44 11885.3 G 8.74 7.16E−02 16.3LYM88 12191.2 P 2.362 3.07E−01 14.9 LYM270 12872.5 G 8.542 7.30E−02 13.7LYM250 12614.1 P 2.156 3.08E−01 4.9 LYM174 12414.2 G 9.38 7.53E−02 24.8LYM129 12573.5 P 2.34 3.12E−01 13.8 LYM61 13174.7 G 8.675 7.55E−02 15.4LYM129 12573.3 P 2.279 3.13E−01 10.9 LYM106 12142.3 G 8.481 7.93E−0212.9 LYM99 12243.1 P 2.452 3.36E−01 19.3 LYM102 12221.1 G 8.523 8.03E−0213.4 LYM178 12164.3 P 2.146 3.40E−01 4.4 LYM100 12134.1 G 8.547 8.05E−0213.7 LYM128 12641.3 P 2.149 3.45E−01 4.6 LYM288 12741.9 G 8.472 8.26E−0212.7 LYM206 12601.2 P 2.588 3.87E−01 25.9 LYM289 12491.1 G 8.5228.40E−02 13.4 LYM157 13341.4 P 2.143 4.06E−01 4.2 LYM173 12981.8 G 8.6498.84E−02 15.1 LYM250 12614.2 P 2.216 4.21E−01 7.8 LYM107 12632.3 G 8.4699.28E−02 12.7 LYM90 12392.1 P 2.121 4.64E−01 3.2 LYM138 12561.3 G 9.899.40E−02 31.6 LYM89 12214.2 P 2.296 4.65E−01 11.7 LYM287 12771.7 G 8.5739.43E−02 14.1 LYM159 13354.5 P 2.143 4.69E−01 4.2 LYM119 12461.4 G10.068 9.61E−02 34 LYM236 12591.1 P 2.305 5.02E−01 12.1 LYM183 12994.8 G8.641 9.88E−02 15 LYM90 12393.1 P 2.202 5.67E−01 7.1 LYM111 12252.2 G9.767 1.10E−01 30 LYM236 12592.4 P 2.266 5.72E−01 10.2 LYM173 12982.7 G8.456 1.10E−01 12.5 LYM175 12654.4 P 2.247 5.93E−01 9.3 LYM291 12753.6 G8.43 1.13E−01 12.2 LYM250 12611.3 P 2.252 6.16E−01 9.6 LYM105 12293.1 G8.749 1.13E−01 16.4 LYM89 12214.3 P 2.192 6.24E−01 6.6 LYM130 12331.3 G9.171 1.24E−01 22 LYM91 13284.3 P 2.216 6.26E−01 7.8 LYM220 12852.4 G8.54 1.27E−01 13.6 LYM283 13304.4 P 2.184 6.55E−01 6.3 LYM90 12393.1 G8.368 1.28E−01 11.4 LYM128 12642.3 P 2.143 6.86E−01 4.3 LYM44 11884.1 G8.324 1.29E−01 10.8 LYM175 12651.2 P 2.091 6.92E−01 1.7 LYM208 13014.7 G8.336 1.38E−01 10.9 LYM91 13283.4 P 2.177 7.80E−01 5.9 LYM152 12371.2 G8.316 1.41E−01 10.7 LYM157 13342.4 P 2.129 8.55E−01 3.6 LYM270 12871.8 G9.587 1.48E−01 27.6 LYM86 12183.1 P 2.086 8.93E−01 1.5 LYM106 12144.3 G8.492 1.51E−01 13 LYM128 12641.1 P 2.081 9.09E−01 1.3 LYM100 12133.1 G9.105 1.51E−01 21.2 LYM6 11733.2 P 2.08 9.12E−01 1.2 LYM291 12751.7 G8.332 1.55E−01 10.9 LYM159 13352.4 P 2.07 9.20E−01 0.7 LYM90 12395.3 G8.261 1.57E−01 9.9 LYM73 12622.2 P 2.085 9.45E−01 1.4 LYM61 13171.7 G9.396 1.58E−01 25 LYM147 12583.1 P 2.095 9.49E−01 1.9 LYM44 11884.3 G8.442 1.59E−01 12.3 CONTROL — P 2.056 — 0 LYM288 12743.5 G 11.0951.61E−01 47.6 LYM165 12973.8 A 91.461 5.84E−02 2.5 LYM174 12411.2 G8.324 1.65E−01 10.8 LYM142 12803.6 A 91.285 7.62E−02 2.3 LYM287 12774.6G 8.768 1.68E−01 16.7 LYM242 13052.5 A 91.179 8.25E−02 2.1 LYM25513082.7 G 9.398 1.69E−01 25.1 LYM142 12804.4 A 91.52 1.16E−01 2.5 LYM14312521.1 G 9.119 1.76E−01 21.4 LYM220 12851.7 A 92.043 1.54E−01 3.1 LYM9012392.1 G 8.32 1.76E−01 10.7 LYM142 12802.9 A 90.734 1.57E−01 1.6 LYM25513082.8 G 10.97 1.80E−01 46 LYM220 12851.13 A 90.671 1.90E−01 1.6 LYM21213034.8 G 9.016 1.83E−01 20 LYM270 12874.7 A 90.187 3.71E−01 1 LYM10212222.2 G 8.422 1.87E−01 12.1 LYM212 13032.8 A 90.258 4.05E−01 1.1LYM242 13054.9 G 9.013 1.90E−01 19.9 LYM165 12973.6 A 90.35 4.28E−01 1.2LYM106 12141.4 G 8.558 2.06E−01 13.9 LYM223 12674.2 A 90.259 4.31E−011.1 LYM107 12631.4 G 9.993 2.10E−01 33 LYM270 12872.5 A 90.341 4.99E−011.2 LYM143 12521.2 G 8.357 2.11E−01 11.2 LYM220 12851.11 A 90.4465.73E−01 1.3 LYM208 13013.9 G 8.782 2.14E−01 16.9 LYM203 12664.1 A89.791 5.92E−01 0.6 LYM138 12562.2 G 8.175 2.14E−01 8.8 LYM165 12972.6 A89.924 6.77E−01 0.7 LYM255 13082.5 G 8.237 2.26E−01 9.6 LYM142 12804.3 A89.663 6.98E−01 0.4 LYM107 12633.4 G 9.106 2.32E−01 21.2 LYM203 12662.3A 89.592 7.80E−01 0.4 LYM142 12804.1 G 10.662 2.37E−01 41.9 LYM21213031.5 A 89.76 8.24E−01 0.6 LYM242 13051.9 G 8.604 2.43E−01 14.5 LYM16512974.5 A 89.451 8.70E−01 0.2 LYM197 12822.5 G 9.435 2.48E−01 25.6LYM142 12801.8 A 89.833 9.02E−01 0.6 LYM44 11882.1 G 9.758 2.48E−01 29.9LYM220 12852.4 A 89.491 9.29E−01 0.2 LYM270 12871.5 G 8.255 2.54E−01 9.9LYM207 13252.2 A 89.464 9.67E−01 0.2 LYM100 12133.3 G 8.864 2.58E−01 18LYM212 13034.9 A 89.317 9.73E−01 0.1 LYM153 12324.1 G 9.765 2.62E−0129.9 CONTROL — A 89.268 — 0 LYM105 12297.2 G 8.081 2.72E−01 7.5 LYM20312662.3 B 0.357 2.54E−03 16.5 LYM102 12222.1 G 8.19 2.75E−01 9 LYM14212804.4 B 0.346 2.59E−02 13.1 LYM119 12463.2 G 8.455 2.83E−01 12.5LYM270 12872.8 B 0.32 1.49E−01 4.5 LYM130 12333.1 G 8.851 2.85E−01 17.8LYM207 13251.5 B 0.32 2.19E−01 4.5 LYM152 12372.2 G 9.446 2.96E−01 25.7LYM242 13051.8 B 0.323 2.70E−01 5.5 LYM198 13002.5 G 8.897 2.97E−01 18.4LYM212 13032.8 B 0.328 3.94E−01 6.9 LYM152 12373.1 G 10.53 3.04E−01 40.1LYM165 12973.5 B 0.311 5.21E−01 1.6 LYM130 12332.2 G 8.949 3.07E−01 19.1LYM165 12974.5 B 0.343 5.67E−01 11.8 LYM208 13013.6 G 8.78 3.08E−01 16.8LYM220 12851.11 B 0.324 5.74E−01 5.9 LYM197 12824.7 G 8.209 3.20E−01 9.2LYM165 12973.6 B 0.339 5.91E−01 10.8 LYM130 12334.1 G 8.524 3.27E−0113.4 LYM212 13034.9 B 0.322 6.03E−01 5.1 LYM153 12322.1 G 10.0783.33E−01 34.1 LYM165 12972.6 B 0.31 6.28E−01 1.2 LYM119 12462.1 G 11.3223.43E−01 50.7 LYM223 12674.5 B 0.311 6.63E−01 1.6 LYM212 13031.6 G 8.3443.43E−01 11 LYM242 13054.9 B 0.321 6.88E−01 4.7 LYM152 12371.3 G 8.8353.43E−01 17.6 LYM223 12674.2 B 0.318 7.66E−01 3.9 LYM255 13081.5 G 8.3693.44E−01 11.4 LYM212 13034.8 B 0.314 8.88E−01 2.6 LYM138 12564.1 G 9.0433.61E−01 20.3 LYM142 12804.3 B 0.308 9.13E−01 0.4 LYM119 12462.2 G 8.7913.63E−01 17 LYM270 12872.7 B 0.308 9.59E−01 0.4 LYM288 12743.8 G 7.9913.87E−01 6.3 CONTROL — B 0.306 — 0 LYM208 13011.6 G 9.207 3.94E−01 22.5LYM270 12872.8 C 3.214 1.73E−02 9 LYM183 12993.8 G 8.732 4.00E−01 16.2LYM242 13051.8 C 3.056 2.19E−01 3.6 LYM220 12851.13 G 7.962 4.01E−01 6LYM203 12662.3 C 3.394 2.48E−01 15.1 LYM220 12852.2 G 8.431 4.14E−0112.2 LYM165 12973.6 C 3.363 2.58E−01 14 LYM111 12251.4 G 7.938 4.15E−015.6 LYM220 12851.11 C 3.088 3.21E−01 4.7 LYM201 12833.9 G 8.436 4.26E−0112.3 LYM270 12872.7 C 3.025 4.73E−01 2.6 LYM119 12461.1 G 8.188 4.34E−019 LYM207 13251.5 C 3.081 4.87E−01 4.5 LYM143 12524.2 G 8.464 4.56E−0112.6 LYM142 12804.3 C 3.006 4.98E−01 1.9 LYM291 12754.9 G 8.193 4.61E−019 LYM165 12974.5 C 3.319 5.38E−01 12.5 LYM198 13005.8 G 7.987 4.62E−016.3 LYM212 13032.8 C 3.144 5.50E−01 6.6 LYM130 12332.1 G 9.025 4.71E−0120.1 LYM242 13054.9 C 3.075 6.60E−01 4.3 LYM201 12834.6 G 9.028 4.74E−0120.1 LYM142 12804.4 C 3.119 6.89E−01 5.7 LYM173 12981.5 G 9.308 4.78E−0123.9 LYM212 13034.9 C 3.069 7.34E−01 4 LYM212 13034.9 G 7.933 4.85E−015.6 LYM212 13034.8 C 3.081 7.88E−01 4.5 LYM105 12294.2 G 8.765 4.98E−0116.6 LYM165 12974.6 C 2.981 8.42E−01 1.1 LYM137 12151.1 G 7.906 5.03E−015.2 LYM223 12674.2 C 2.981 8.42E−01 1.1 LYM197 12821.11 G 8.258 5.15E−019.9 CONTROL — C 2.949 — 0 LYM208 13012.5 G 8.238 5.34E−01 9.6 LYM16512973.8 D 0.32 2.37E−03 23 LYM289 12493.2 G 9.265 5.36E−01 23.3 LYM20713251.6 D 0.305 1.11E−02 17.4 LYM137 12153.1 G 8.62 5.42E−01 14.7 LYM16512973.6 D 0.36 3.31E−02 38.6 LYM137 12151.2 G 10.046 5.51E−01 33.7LYM207 13251.4 D 0.295 5.21E−02 13.4 LYM142 12801.8 G 8.686 5.67E−0115.6 LYM203 12664.1 D 0.295 1.18E−01 13.7 LYM138 12562.1 G 7.8195.85E−01 4.1 LYM142 12804.4 D 0.327 1.20E−01 25.7 LYM288 12744.7 G 8.8955.96E−01 18.4 LYM220 12851.7 D 0.289 1.21E−01 11.3 LYM183 12991.7 G8.057 6.16E−01 7.2 LYM212 13034.9 D 0.321 1.28E−01 23.6 LYM198 13002.8 G7.831 6.34E−01 4.2 LYM203 12662.3 D 0.392 1.71E−01 50.9 LYM242 13053.7 G7.802 6.36E−01 3.8 LYM165 12972.6 D 0.337 2.51E−01 29.6 LYM198 13004.6 G8.078 6.38E−01 7.5 LYM142 12802.9 D 0.288 2.59E−01 10.9 LYM291 12751.1 G7.808 6.53E−01 3.9 LYM220 12851.11 D 0.275 2.93E−01 5.7 LYM107 12631.2 G8.188 6.54E−01 9 LYM165 12974.5 D 0.366 3.60E−01 40.7 LYM111 12251.3 G8.43 6.54E−01 12.2 LYM142 12804.3 D 0.28 3.67E−01 7.9 LYM111 12254.4 G8.21 6.60E−01 9.3 LYM212 13032.8 D 0.313 3.99E−01 20.5 LYM173 12982.6 G8.196 6.75E−01 9.1 LYM207 13251.5 D 0.271 4.58E−01 4.2 LYM90 12394.2 G7.749 6.78E−01 3.1 LYM212 13034.8 D 0.326 4.77E−01 25.5 LYM289 12492.2 G7.878 6.78E−01 4.8 LYM242 13051.8 D 0.317 5.01E−01 22.2 LYM270 12873.6 G8.656 6.86E−01 15.2 LYM242 13054.9 D 0.296 5.23E−01 14 LYM142 12804.3 G8.105 6.98E−01 7.9 LYM142 12801.8 D 0.277 5.35E−01 6.7 LYM291 12751.2 G8.022 6.99E−01 6.7 LYM270 12871.7 D 0.266 6.43E−01 2.4 LYM107 12632.1 G8.133 7.08E−01 8.2 LYM165 12973.5 D 0.285 6.48E−01 9.5 LYM106 12142.2 G7.736 7.26E−01 3 LYM203 12664.2 D 0.273 7.59E−01 5.1 LYM142 12803.6 G7.723 7.27E−01 2.8 LYM142 12804.1 D 0.271 8.59E−01 4.2 LYM61 13174.5 G7.916 7.37E−01 5.3 LYM270 12872.7 D 0.262 8.71E−01 0.8 LYM270 12872.7 G7.673 7.48E−01 2.1 LYM223 12674.2 D 0.261 9.23E−01 0.5 LYM220 12851.8 G8.082 7.70E−01 7.6 CONTROL — D 0.26 — 0 LYM152 12373.2 G 7.82 7.80E−014.1 LYM165 12973.8 E 8.625 4.10E−04 12 LYM201 12831.5 G 7.64 7.97E−011.7 LYM212 13034.9 E 8.438 1.77E−03 9.6 LYM198 13005.6 G 7.688 8.21E−012.3 LYM165 12973.6 E 8.75 4.04E−03 13.6 LYM111 12254.3 G 7.707 8.31E−012.6 LYM165 12972.6 E 8.313 5.10E−03 7.9 LYM198 13002.6 G 7.837 8.35E−014.3 LYM142 12803.6 E 8.188 1.61E−02 6.3 LYM143 12523.4 G 7.685 8.37E−012.3 LYM207 13251.5 E 8.188 1.61E−02 6.3 LYM197 12824.4 G 7.755 8.48E−013.2 LYM203 12664.1 E 9 5.72E−02 16.9 LYM201 12833.6 G 7.594 8.73E−01 1.1LYM220 12851.11 E 8 8.14E−02 3.9 LYM208 13012.8 G 7.631 9.07E−01 1.6LYM142 12804.4 E 8.313 1.00E−01 7.9 LYM106 12144.4 G 7.553 9.41E−01 0.5LYM212 13034.8 E 8.438 2.09E−01 9.6 LYM102 12222.6 G 7.564 9.61E−01 0.7LYM203 12662.3 E 8.625 2.09E−01 12 LYM220 12851.11 G 7.521 9.92E−01 0.1LYM165 12974.5 E 8.313 2.60E−01 7.9 CONTROL — G 7.514 — 0 LYM212 13032.8E 8.313 2.60E−01 7.9 LYM174 12414.3 H 16.748 1.00E−06 72.1 LYM22012851.7 E 8.25 3.59E−01 7.1 LYM288 12743.9 H 13.843 3.30E−05 42.2 LYM27012871.7 E 7.938 4.08E−01 3.1 LYM255 13082.8 H 13.698 4.70E−05 40.7LYM142 12801.8 E 8 4.22E−01 3.9 LYM106 12144.4 H 12.994 2.04E−04 33.5LYM207 13251.6 E 8 4.22E−01 3.9 LYM270 12873.6 H 12.695 4.90E−04 30.4LYM142 12804.1 E 8.125 4.47E−01 5.5 LYM289 12492.2 H 12.141 1.30E−0324.7 LYM223 12674.2 E 7.813 5.05E−01 1.4 LYM105 12294.2 H 11.9671.87E−03 22.9 LYM270 12872.5 E 8.125 5.48E−01 5.5 LYM130 12332.1 H15.426 3.71E−03 58.5 LYM242 13051.8 E 8.063 5.55E−01 4.7 LYM153 12323.2H 14.628 4.86E−03 50.3 LYM142 12802.9 E 8 5.67E−01 3.9 LYM130 12334.1 H12.621 5.52E−03 29.7 LYM203 12664.2 E 7.75 8.10E−01 0.6 LYM137 12153.1 H11.476 7.32E−03 17.9 LYM142 12804.3 E 7.813 8.76E−01 1.4 LYM153 12324.2H 13.515 7.63E−03 38.9 LYM242 13052.5 E 7.75 8.83E−01 0.6 LYM173 12981.6H 11.701 8.10E−03 20.2 LYM220 12851.13 E 7.75 9.38E−01 0.6 LYM13812561.1 H 21.81 8.93E−03 124.1 LYM242 13054.9 E 7.75 9.50E−01 0.6 LYM28912493.1 H 14.547 1.07E−02 49.5 CONTROL — E 7.701 — 0 LYM119 12461.4 H16.244 1.16E−02 66.9 LYM165 12973.6 F 0.596 7.95E−02 13.5 LYM102 12222.2H 13.408 1.46E−02 37.7 LYM142 12804.4 F 0.592 1.09E−01 12.7 LYM10212222.3 H 11.638 1.94E−02 19.6 LYM165 12973.8 F 0.586 1.31E−01 11.7LYM105 12297.2 H 12.783 2.07E−02 31.3 LYM203 12664.1 F 0.633 2.49E−0120.5 LYM107 12631.2 H 11.091 2.27E−02 14 LYM203 12662.3 F 0.694 2.67E−0132.3 LYM138 12561.3 H 16.524 3.41E−02 69.8 LYM242 13051.8 F 0.5823.48E−01 10.9 LYM119 12461.1 H 15.582 6.22E−02 60.1 LYM207 13251.6 F0.561 3.53E−01 6.8 LYM105 12293.1 H 13.558 6.63E−02 39.3 LYM242 13054.9F 0.57 4.74E−01 8.5 LYM106 12141.4 H 11.104 7.61E−02 14.1 LYM212 13034.8F 0.587 5.70E−01 11.8 LYM212 13032.8 H 11.593 7.79E−02 19.1 LYM16512972.6 F 0.557 5.84E−01 6 LYM119 12463.2 H 15.335 8.15E−02 57.6 LYM16512974.5 F 0.578 6.31E−01 10 LYM105 12295.2 H 12.855 8.74E−02 32.1 LYM21213034.9 F 0.54 7.29E−01 2.9 LYM173 12982.6 H 10.659 8.92E−02 9.5 LYM14212804.1 F 0.541 7.41E−01 3 LYM111 12254.4 H 11.442 9.17E−02 17.6 LYM20713251.4 F 0.538 7.77E−01 2.4 LYM174 12411.2 H 13.791 1.04E−01 41.7LYM165 12973.5 F 0.534 8.72E−01 1.6 LYM220 12851.8 H 15.087 1.22E−01 55LYM212 13032.8 F 0.527 9.61E−01 0.5 LYM105 12294.3 H 10.846 1.28E−0111.4 CONTROL — F 0.525 — 0 LYM137 12151.4 H 13.064 1.38E−01 34.2 LYM20312662.3 G 10.773 2.09E−01 11.7 LYM174 12412.1 H 14.775 1.64E−01 51.8LYM223 12671.2 G 10.217 5.89E−01 6 LYM106 12142.2 H 15.871 1.65E−01 63.1LYM212 13034.8 G 10.024 7.08E−01 4 LYM130 12332.2 H 12.921 1.74E−01 32.8LYM142 12804.1 G 9.731 8.40E−01 0.9 LYM242 13051.8 H 11.319 1.75E−0116.3 LYM270 12871.7 G 9.681 9.77E−01 0.4 LYM107 12632.3 H 14.7681.82E−01 51.7 CONTROL — G 9.641 — 0 LYM152 12373.1 H 11.022 2.05E−0113.2 LYM165 12973.6 H 16.961 8.98E−04 45.3 LYM137 12151.1 H 12.6582.07E−01 30 LYM165 12973.8 H 14.778 4.30E−03 26.6 LYM153 12324.1 H14.197 2.09E−01 45.9 LYM207 13251.6 H 14.326 3.04E−02 22.7 LYM10712631.4 H 11.147 2.14E−01 14.5 LYM142 12804.4 H 15.589 3.30E−02 33.5LYM119 12462.1 H 14.806 2.26E−01 52.1 LYM203 12664.1 H 14.085 5.01E−0220.7 LYM138 12562.2 H 12.098 2.27E−01 24.3 LYM212 13034.9 H 14.9939.74E−02 28.4 LYM289 12491.1 H 10.624 2.38E−01 9.1 LYM203 12662.3 H19.328 1.50E−01 65.6 LYM174 12411.3 H 15.539 2.45E−01 59.6 LYM16512972.6 H 15.617 2.04E−01 33.8 LYM137 12151.2 H 12.694 2.45E−01 30.4LYM207 13251.5 H 12.719 2.12E−01 9 LYM153 12322.1 H 10.728 2.52E−01 10.2LYM220 12851.7 H 13.019 2.47E−01 11.5 LYM111 12252.2 H 12.372 2.55E−0127.1 LYM207 13251.4 H 13.224 2.75E−01 13.3 LYM288 12743.8 H 11.7152.62E−01 20.4 LYM220 12851.11 H 12.536 3.05E−01 7.4 LYM287 12774.6 H10.425 2.70E−01 7.1 LYM165 12974.5 H 17.137 3.08E−01 46.8 LYM288 12743.5H 14.237 2.75E−01 46.3 LYM212 13032.8 H 14.504 4.27E−01 24.3 LYM24213052.5 H 10.922 2.99E−01 12.2 LYM212 13034.8 H 15.169 4.30E−01 29.9LYM107 12631.1 H 11.258 3.08E−01 15.7 LYM142 12801.8 H 12.83 4.42E−019.9 LYM100 12131.3 H 10.877 3.20E−01 11.7 LYM142 12802.9 H 12.8294.65E−01 9.9 LYM289 12491.4 H 10.577 3.20E−01 8.7 LYM242 13054.9 H13.501 4.67E−01 15.7 LYM90 12395.3 H 11.546 3.34E−01 18.6 LYM242 13051.8H 14.412 5.21E−01 23.5 LYM102 12222.1 H 10.714 3.34E−01 10.1 LYM14212804.3 H 12.49 5.36E−01 7 LYM197 12821.6 H 11.08 3.37E−01 13.8 LYM16512973.5 H 12.626 6.39E−01 8.2 LYM255 13082.7 H 13.691 3.37E−01 40.7LYM223 12674.2 H 11.968 7.07E−01 2.5 LYM119 12462.2 H 13.506 3.41E−0138.8 LYM142 12804.1 H 12.327 8.32E−01 5.6 LYM152 12371.2 H 14.3313.57E−01 47.2 LYM203 12664.2 H 12.083 8.49E−01 3.5 LYM153 12321.2 H12.36 3.58E−01 27 LYM270 12871.7 H 11.794 8.95E−01 1 LYM287 12771.6 H10.273 3.68E−01 5.5 LYM270 12872.7 H 11.754 9.22E−01 0.7 LYM289 12493.2H 14.017 3.69E−01 44 CONTROL — H 11.673 — 0 LYM106 12144.3 H 12.3563.75E−01 26.9 LYM203 12662.3 J 0.046 2.04E−03 50.5 LYM255 13082.5 H14.481 3.83E−01 48.8 LYM165 12973.6 J 0.042 6.22E−03 38.8 LYM288 12741.9H 11.834 4.12E−01 21.6 LYM165 12974.5 J 0.043 1.62E−02 41 LYM138 12564.1H 11.616 4.26E−01 19.3 LYM165 12972.6 J 0.039 4.57E−02 29.2 LYM29112754.9 H 12.303 4.35E−01 26.4 LYM142 12804.4 J 0.038 6.13E−02 25.6LYM102 12221.1 H 10.824 4.81E−01 11.2 LYM212 13034.8 J 0.038 9.39E−0226.4 LYM152 12371.3 H 11.586 4.88E−01 19 LYM212 13034.9 J 0.037 1.03E−0122.1 LYM255 13082.9 H 10.851 5.04E−01 11.5 LYM165 12973.8 J 0.0371.07E−01 21.7 LYM130 12331.3 H 12.714 5.44E−01 30.6 LYM212 13032.8 J0.037 1.53E−01 20.9 LYM212 13031.6 H 10.172 5.47E−01 4.5 LYM242 13051.8J 0.037 1.67E−01 20.7 LYM143 12524.7 H 11.939 5.72E−01 22.7 LYM20713251.6 J 0.036 1.84E−01 17.5 LYM173 12981.5 H 10.649 5.74E−01 9.4LYM203 12664.1 J 0.035 2.26E−01 16 LYM106 12142.3 H 10.139 5.74E−01 4.2LYM207 13251.4 J 0.035 2.79E−01 14.1 LYM142 12802.9 H 11.041 5.91E−0113.4 LYM142 12802.9 J 0.035 3.01E−01 14 LYM198 13005.8 H 10.183 5.92E−014.6 LYM220 12851.7 J 0.035 3.06E−01 13.9 LYM102 12222.6 H 10.7596.01E−01 10.5 LYM242 13054.9 J 0.034 3.48E−01 13 LYM137 12154.5 H 12.3546.05E−01 26.9 LYM165 12973.5 J 0.034 3.92E−01 12.3 LYM201 12834.6 H10.294 7.03E−01 5.8 LYM142 12804.3 J 0.033 4.73E−01 9.4 LYM183 12994.8 H11.314 7.10E−01 16.2 LYM203 12664.2 J 0.033 5.96E−01 7.4 LYM44 11885.4 H10.256 7.27E−01 5.4 LYM220 12851.11 J 0.032 6.35E−01 6.1 LYM242 13053.7H 10.093 7.36E−01 3.7 LYM142 12804.1 J 0.032 6.79E−01 6 LYM291 12753.6 H10.337 7.51E−01 6.2 LYM242 13053.7 J 0.032 6.82E−01 5.5 LYM143 12524.5 H10.926 7.58E−01 12.2 LYM142 12801.8 J 0.031 7.91E−01 3.5 LYM201 12833.7H 9.927 7.73E−01 2 LYM270 12871.7 J 0.031 8.11E−01 3 LYM130 12333.1 H10.353 7.92E−01 6.4 LYM223 12674.2 J 0.031 9.08E−01 1.6 LYM287 12773.7 H10.34 8.02E−01 6.2 LYM207 13251.5 J 0.031 9.50E−01 0.8 LYM183 12993.7 H10.225 8.25E−01 5 CONTROL — J 0.03 — 0 LYM183 12994.7 H 9.924 8.96E−01 2LYM207 13251.5 K 0.594 5.66E−02 26.1 LYM212 13034.9 H 10.157 9.25E−014.4 LYM165 12973.6 K 0.578 9.58E−02 22.8 LYM208 13012.5 H 9.992 9.35E−012.7 LYM203 12664.1 K 0.575 1.28E−01 22.2 CONTROL — H 9.733 — 0 LYM20312662.3 K 0.564 1.31E−01 19.8 LYM138 12561.1 J 0.044 0.00E+00 114 LYM22012851.7 K 0.543 2.71E−01 15.2 LYM119 12461.1 J 0.037 1.00E−06 76.2LYM207 13251.6 K 0.536 3.18E−01 13.9 LYM138 12561.3 J 0.035 5.00E−0669.7 LYM212 13034.9 K 0.53 3.55E−01 12.6 LYM174 12414.3 J 0.036 1.20E−0571.7 LYM212 13034.8 K 0.533 3.98E−01 13.1 LYM119 12461.4 J 0.0341.30E−05 64.1 LYM165 12974.5 K 0.522 4.02E−01 10.8 LYM119 12463.2 J0.034 1.90E−05 64.3 LYM165 12973.8 K 0.522 4.55E−01 10.8 LYM107 12632.3J 0.034 7.40E−05 63 LYM223 12672.5 K 0.513 5.04E−01 8.9 LYM106 12142.2 J0.034 1.01E−04 65.8 LYM142 12804.1 K 0.514 5.15E−01 9.2 LYM153 12324.1 J0.033 1.07E−04 60.5 LYM223 12671.2 K 0.512 5.28E−01 8.8 LYM153 12323.2 J0.032 1.80E−04 53.5 LYM242 13054.9 K 0.504 6.16E−01 7.1 LYM137 12151.4 J0.031 1.99E−04 50.4 LYM212 13032.8 K 0.501 6.28E−01 6.4 LYM220 12851.8 J0.032 2.34E−04 54.5 LYM223 12674.5 K 0.496 6.88E−01 5.3 LYM130 12332.1 J0.031 2.64E−04 50.1 LYM212 13033.6 K 0.489 7.67E−01 4 LYM174 12411.3 J0.034 3.59E−04 63.7 LYM165 12972.6 K 0.491 7.69E−01 4.3 LYM105 12293.1 J0.031 6.37E−04 49.9 LYM203 12663.2 K 0.488 7.77E−01 3.6 LYM174 12412.1 J0.032 8.23E−04 51.7 LYM142 12804.4 K 0.48 8.75E−01 2 LYM105 12295.2 J0.031 1.04E−03 48 LYM207 13252.2 K 0.479 8.90E−01 1.8 LYM289 12493.1 J0.03 1.42E−03 44.8 LYM242 13051.8 K 0.479 8.95E−01 1.7 LYM255 13082.5 J0.032 1.50E−03 56.1 LYM142 12801.8 K 0.479 9.03E−01 1.7 LYM153 12324.2 J0.03 1.83E−03 45.6 LYM270 12872.5 K 0.479 9.09E−01 1.7 LYM106 12144.4 J0.029 1.94E−03 40.2 LYM212 13032.6 K 0.477 9.20E−01 1.4 LYM102 12222.2 J0.029 2.58E−03 41.7 LYM207 13251.4 K 0.477 9.26E−01 1.2 LYM288 12743.5 J0.03 2.77E−03 46 LYM220 12851.13 K 0.477 9.27E−01 1.2 LYM105 12294.2 J0.029 3.58E−03 39 LYM142 12803.6 K 0.476 9.37E−01 1.1 LYM174 12411.2 J0.03 3.72E−03 44.5 CONTROL — K 0.471 — 0 LYM137 12151.1 J 0.029 3.78E−0338.1 LYM203 12662.3 L 2.454 6.01E−04 67.5 LYM119 12462.1 J 0.03 3.98E−0343.3 LYM165 12973.6 L 2.138 6.78E−03 45.9 LYM288 12743.9 J 0.0294.98E−03 37.8 LYM165 12974.5 L 2.15 1.34E−02 46.8 LYM152 12371.2 J 0.0315.43E−03 50.5 LYM142 12804.4 L 1.961 3.94E−02 33.9 LYM138 12562.2 J0.029 5.54E−03 38.3 LYM165 12972.6 L 1.948 5.24E−02 33 LYM137 12151.2 J0.028 6.64E−03 36.8 LYM212 13034.9 L 1.862 9.49E−02 27.2 LYM173 12981.6J 0.028 7.33E−03 34.4 LYM212 13034.8 L 1.905 9.76E−02 30 LYM270 12873.6J 0.028 7.96E−03 36.4 LYM165 12973.8 L 1.832 1.21E−01 25.1 LYM25513082.8 J 0.028 8.97E−03 35.1 LYM207 13251.6 L 1.819 1.25E−01 24.2LYM119 12462.2 J 0.029 1.07E−02 37.4 LYM203 12664.1 L 1.796 1.54E−0122.6 LYM255 13082.7 J 0.029 1.24E−02 37.2 LYM212 13032.8 L 1.8071.78E−01 23.3 LYM212 13032.8 J 0.027 1.37E−02 31.2 LYM242 13051.8 L1.792 1.99E−01 22.3 LYM153 12321.2 J 0.027 1.78E−02 31.6 LYM242 13054.9L 1.709 3.00E−01 16.7 LYM105 12297.2 J 0.027 1.78E−02 30.6 LYM20713251.4 L 1.685 3.34E−01 15 LYM111 12252.2 J 0.027 2.00E−02 31.9 LYM22012851.7 L 1.652 4.23E−01 12.8 LYM130 12334.1 J 0.026 2.61E−02 26.9LYM142 12802.9 L 1.618 5.12E−01 10.5 LYM106 12144.3 J 0.027 2.82E−0230.8 LYM165 12973.5 L 1.595 5.81E−01 8.9 LYM289 12493.2 J 0.028 3.23E−0234.8 LYM207 13251.5 L 1.589 5.87E−01 8.5 LYM137 12153.1 J 0.026 3.50E−0226.5 LYM142 12804.3 L 1.581 6.12E−01 7.9 LYM152 12373.1 J 0.026 3.60E−0226.5 LYM142 12801.8 L 1.568 6.52E−01 7.1 LYM197 12821.6 J 0.026 3.74E−0225.9 LYM220 12851.11 L 1.564 6.64E−01 6.7 LYM130 12332.2 J 0.0264.55E−02 27.4 LYM142 12804.1 L 1.55 7.25E−01 5.8 LYM90 12395.3 J 0.0264.79E−02 25.8 LYM203 12664.2 L 1.524 7.99E−01 4.1 LYM288 12743.8 J 0.0265.52E−02 24.7 LYM223 12674.2 L 1.508 8.52E−01 3 LYM287 12771.6 J 0.0265.89E−02 23.5 LYM242 13053.7 L 1.491 9.09E−01 1.8 LYM201 12833.7 J 0.0256.60E−02 22.3 LYM270 12871.7 L 1.471 9.76E−01 0.5 LYM102 12222.3 J 0.0267.07E−02 22.7 LYM203 12663.2 L 1.467 9.91E−01 0.2 LYM173 12981.5 J 0.0267.84E−02 23.1 CONTROL — L 1.465 — 0 LYM291 12754.9 J 0.026 8.08E−02 26.4LYM203 12662.3 M 0.307 6.02E−04 65.1 LYM111 12254.4 J 0.025 8.41E−02 22LYM165 12973.6 M 0.267 7.02E−03 43.8 LYM130 12331.3 J 0.027 8.47E−02 31LYM165 12974.5 M 0.269 1.43E−02 44.6 LYM153 12322.1 J 0.025 1.13E−0119.3 LYM142 12804.4 M 0.245 4.25E−02 31.9 LYM102 12221.1 J 0.0251.20E−01 20 LYM165 12972.6 M 0.244 5.69E−02 31 LYM107 12631.4 J 0.0251.20E−01 20.2 LYM212 13034.9 M 0.233 1.04E−01 25.3 LYM143 12524.7 J0.026 1.22E−01 26.9 LYM212 13034.8 M 0.238 1.07E−01 28.1 LYM102 12222.1J 0.025 1.30E−01 19.7 LYM165 12973.8 M 0.229 1.33E−01 23.2 LYM18312994.8 J 0.026 1.32E−01 24.3 LYM207 13251.6 M 0.227 1.38E−01 22.4LYM107 12631.2 J 0.025 1.38E−01 18.9 LYM203 12664.1 M 0.224 1.69E−0120.8 LYM288 12741.9 J 0.025 1.56E−01 19.2 LYM212 13032.8 M 0.2261.96E−01 21.5 LYM212 13031.6 J 0.024 1.70E−01 16.3 LYM242 13051.8 M0.224 2.19E−01 20.5 LYM137 12154.5 J 0.026 1.75E−01 22.8 LYM242 13054.9M 0.214 3.31E−01 14.9 LYM289 12492.2 J 0.025 1.76E−01 20.6 LYM20713251.4 M 0.211 3.69E−01 13.3 LYM152 12371.3 J 0.025 1.77E−01 20.4LYM220 12851.7 M 0.206 4.66E−01 11.1 LYM138 12564.1 J 0.025 1.84E−01 19LYM142 12802.9 M 0.202 5.62E−01 8.9 LYM242 13051.8 J 0.024 1.87E−01 17.1LYM165 12973.5 M 0.199 6.37E−01 7.3 LYM105 12294.3 J 0.024 1.91E−01 16.8LYM207 13251.5 M 0.199 6.45E−01 6.9 LYM106 12141.4 J 0.024 1.95E−01 16.3LYM142 12804.3 M 0.198 6.72E−01 6.3 LYM255 13082.9 J 0.024 2.05E−01 16.4LYM142 12801.8 M 0.196 7.14E−01 5.5 LYM130 12333.1 J 0.024 2.15E−01 16.4LYM220 12851.11 M 0.195 7.28E−01 5.2 LYM142 12802.9 J 0.024 2.26E−0117.3 LYM142 12804.1 M 0.194 7.89E−01 4.3 LYM242 13052.5 J 0.024 2.31E−0114.8 LYM203 12664.2 M 0.191 8.68E−01 2.5 LYM107 12631.1 J 0.024 2.35E−0115.8 LYM223 12674.2 M 0.188 9.25E−01 1.4 LYM183 12993.5 J 0.024 2.40E−0115.5 LYM242 13053.7 M 0.186 9.85E−01 0.3 LYM201 12834.6 J 0.024 2.60E−0113.6 CONTROL — M 0.186 — 0 LYM183 12993.7 J 0.024 2.63E−01 15.1 LYM20312662.3 N 0.264 3.40E−02 25.7 LYM106 12142.3 J 0.024 3.01E−01 13.1LYM165 12973.6 N 0.252 7.08E−02 19.8 LYM212 13034.9 J 0.024 3.25E−0117.3 LYM207 13251.6 N 0.239 2.15E−01 13.5 LYM107 12632.1 J 0.0233.27E−01 13 LYM165 12974.5 N 0.245 2.21E−01 16.6 LYM102 12222.6 J 0.0233.49E−01 12.4 LYM203 12664.1 N 0.236 2.76E−01 12.4 LYM143 12524.5 J0.024 3.52E−01 15.7 LYM165 12972.6 N 0.238 2.78E−01 13.2 LYM291 12753.6J 0.023 3.61E−01 12.4 LYM212 13034.9 N 0.235 2.89E−01 11.8 LYM19813005.8 J 0.023 3.80E−01 10.4 LYM212 13034.8 N 0.238 2.99E−01 13.2LYM287 12771.7 J 0.023 4.35E−01 9.5 LYM142 12804.4 N 0.227 4.59E−01 8LYM201 12833.9 J 0.023 4.54E−01 9.4 LYM165 12973.8 N 0.222 6.03E−01 5.6LYM142 12804.3 J 0.023 4.60E−01 11.2 LYM242 13053.7 N 0.222 6.06E−01 5.7LYM270 12871.7 J 0.023 4.62E−01 9.4 LYM142 12804.1 N 0.223 6.06E−01 5.9LYM142 12801.8 J 0.023 4.62E−01 9 LYM142 12802.9 N 0.22 6.96E−01 4.3LYM287 12773.7 J 0.023 4.62E−01 10.2 LYM242 13051.8 N 0.218 7.46E−01 3.8LYM289 12491.4 J 0.023 4.64E−01 8.6 LYM270 12871.7 N 0.218 7.46E−01 3.5LYM173 12982.7 J 0.023 4.68E−01 11.3 LYM165 12973.5 N 0.217 7.75E−01 3.3LYM208 13012.5 J 0.023 4.71E−01 12.1 LYM220 12851.7 N 0.217 7.88E−01 3.1LYM44 11885.4 J 0.022 5.57E−01 7.6 LYM212 13032.8 N 0.217 7.96E−01 3LYM105 12297.1 J 0.022 5.76E−01 7.3 LYM242 13054.9 N 0.213 9.14E−01 1.2LYM270 12871.8 J 0.022 5.94E−01 7.6 LYM207 13251.4 N 0.213 9.16E−01 1.1LYM255 13081.5 J 0.022 5.99E−01 8 LYM203 12664.2 N 0.213 9.31E−01 1LYM270 12871.5 J 0.023 6.13E−01 9.1 LYM142 12804.3 N 0.212 9.52E−01 0.6LYM111 12251.1 J 0.022 6.31E−01 5.9 LYM203 12663.2 N 0.211 9.76E−01 0.3LYM289 12491.1 J 0.022 6.50E−01 5.6 LYM220 12851.11 N 0.211 9.90E−01 0.1LYM242 13053.7 J 0.022 6.73E−01 5.4 CONTROL — N 0.21 — 0 LYM183 12994.7J 0.022 7.41E−01 4.1 LYM165 12973.6 O 2.12 1.10E−03 43.2 LYM270 12872.7J 0.022 7.82E−01 3.7 LYM165 12973.8 O 1.847 4.09E−03 24.8 LYM197 12824.4J 0.021 7.94E−01 3.2 LYM207 13251.6 O 1.791 3.64E−02 20.9 LYM287 12774.6J 0.022 7.96E−01 3.5 LYM142 12804.4 O 1.949 4.00E−02 31.6 LYM173 12982.6J 0.021 8.19E−01 2.9 LYM203 12664.1 O 1.761 6.02E−02 18.9 LYM208 13013.6J 0.021 8.22E−01 3 LYM212 13034.9 O 1.874 1.12E−01 26.6 LYM100 12131.3 J0.021 8.23E−01 2.8 LYM203 12662.3 O 2.416 1.58E−01 63.2 LYM143 12521.2 J0.021 8.76E−01 2 LYM165 12972.6 O 1.952 2.19E−01 31.8 LYM143 12523.4 J0.021 8.78E−01 2.7 LYM207 13251.5 O 1.59 2.62E−01 7.4 LYM212 13034.8 J0.021 8.79E−01 1.9 LYM220 12851.7 O 1.627 2.95E−01 9.9 LYM198 13004.6 J0.021 8.86E−01 1.7 LYM207 13251.4 O 1.653 3.18E−01 11.6 LYM143 12521.1 J0.021 9.11E−01 1.3 LYM165 12974.5 O 2.142 3.19E−01 44.7 LYM291 12751.2 J0.021 9.32E−01 1 LYM220 12851.11 O 1.567 3.79E−01 5.8 LYM100 12133.3 J0.021 9.61E−01 0.6 LYM212 13034.8 O 1.896 4.48E−01 28.1 LYM152 12372.2 J0.021 9.80E−01 0.3 LYM212 13032.8 O 1.813 4.49E−01 22.4 LYM208 13012.8 J0.021 9.84E−01 0.3 LYM142 12801.8 O 1.604 5.02E−01 8.3 CONTROL — J 0.021— 0 LYM242 13054.9 O 1.688 5.03E−01 14 LYM288 12741.9 K 0.713 2.72E−0113.6 LYM142 12802.9 O 1.604 5.24E−01 8.3 LYM119 12462.2 K 0.706 3.08E−0112.4 LYM242 13051.8 O 1.802 5.42E−01 21.7 LYM289 12493.1 K 0.7043.13E−01 12.1 LYM142 12804.3 O 1.561 6.15E−01 5.4 LYM142 12804.1 K 0.6953.86E−01 10.7 LYM165 12973.5 O 1.578 6.95E−01 6.6 LYM44 11882.1 K 0.6953.88E−01 10.7 LYM223 12674.2 O 1.496 8.67E−01 1 LYM143 12524.7 K 0.6884.41E−01 9.5 LYM142 12804.1 O 1.541 8.75E−01 4.1 LYM61 13174.7 K 0.6954.79E−01 10.7 LYM203 12664.2 O 1.51 9.11E−01 2 LYM119 12461.4 K 0.6765.05E−01 7.6 CONTROL — O 1.481 — 0 LYM137 12154.5 K 0.675 5.37E−01 7.5LYM165 12973.6 P 2.643 2.53E−03 17.9 LYM61 13174.5 K 0.675 5.82E−01 7.5LYM207 13251.6 P 2.525 1.43E−02 12.6 LYM183 12994.7 K 0.665 6.12E−01 5.9LYM165 12973.8 P 2.472 3.44E−02 10.2 LYM102 12222.3 K 0.663 6.21E−01 5.6LYM203 12662.3 P 2.9 8.02E−02 29.3 LYM174 12414.3 K 0.663 6.23E−01 5.6LYM142 12804.4 P 2.42 1.34E−01 7.9 LYM220 12851.8 K 0.657 6.76E−01 4.7LYM207 13251.4 P 2.389 1.67E−01 6.5 LYM255 13082.7 K 0.657 6.95E−01 4.7LYM203 12664.1 P 2.478 3.11E−01 10.5 LYM289 12493.2 K 0.653 7.43E−01 4LYM212 13034.9 P 2.45 3.23E−01 9.2 LYM198 13005.8 K 0.65 7.67E−01 3.5LYM165 12972.6 P 2.558 3.80E−01 14.1 LYM111 12252.2 K 0.649 7.68E−01 3.3LYM270 12871.7 P 2.314 4.47E−01 3.2 LYM90 12395.1 K 0.65 7.75E−01 3.5LYM212 13032.8 P 2.37 4.77E−01 5.7 LYM242 13052.5 K 0.649 7.83E−01 3.3LYM165 12974.5 P 2.607 4.77E−01 16.2 LYM289 12491.1 K 0.647 7.89E−01 3LYM242 13051.8 P 2.422 4.96E−01 8 LYM153 12322.1 K 0.645 8.11E−01 2.7LYM212 13034.8 P 2.57 5.11E−01 14.6 LYM105 12297.2 K 0.644 8.23E−01 2.7LYM242 13054.9 P 2.358 6.45E−01 5.1 LYM44 11885.3 K 0.643 8.28E−01 2.5LYM142 12802.9 P 2.286 6.67E−01 1.9 LYM102 12222.6 K 0.643 8.39E−01 2.5LYM165 12973.5 P 2.315 7.84E−01 3.2 LYM288 12744.7 K 0.643 8.42E−01 2.5LYM203 12664.2 P 2.28 8.53E−01 1.7 LYM291 12754.9 K 0.643 8.48E−01 2.5LYM142 12804.1 P 2.276 8.85E−01 1.5 LYM107 12631.4 K 0.641 8.56E−01 2.1LYM220 12851.7 P 2.26 9.04E−01 0.8 LYM291 12751.7 K 0.64 8.64E−01 2LYM270 12872.7 P 2.25 9.41E−01 0.3 LYM288 12743.9 K 0.64 8.66E−01 2LYM142 12804.3 P 2.245 9.83E−01 0.1 LYM174 12414.2 K 0.64 8.72E−01 2CONTROL — P 2.243 — 0 LYM90 12392.1 K 0.64 8.76E−01 1.9 LYM4 11701.1 A93.653 1.73E−03 4 LYM143 12523.4 K 0.641 8.77E−01 2.1 LYM21 11672.4 A93.589 1.90E−03 3.9 LYM111 12251.3 K 0.639 8.79E−01 1.8 LYM162 12231.3 A93.4 2.63E−03 3.7 LYM102 12221.1 K 0.636 9.12E−01 1.3 LYM1 11602.6 A93.352 2.88E−03 3.7 LYM102 12221.2 K 0.633 9.47E−01 0.8 LYM4 11702.3 A93.289 3.25E−03 3.6 LYM174 12412.1 K 0.631 9.60E−01 0.6 LYM129 12571.3 A93.281 3.37E−03 3.6 LYM255 13082.8 K 0.63 9.70E−01 0.4 LYM2 11692.3 A93.197 3.86E−03 3.5 LYM137 12152.1 K 0.629 9.82E−01 0.3 LYM2 11695.3 A93.169 4.02E−03 3.5 LYM44 11884.1 K 0.628 9.94E−01 0.1 LYM174 12411.2 A93.189 4.79E−03 3.5 CONTROL — K 0.628 — 0 LYM129 12573.5 A 93.2645.07E−03 3.6 LYM138 12561.1 L 2.7 0.00E+00 124.8 LYM9 11632.2 A 92.9635.75E−03 3.2 LYM174 12414.3 L 2.075 1.50E−05 72.8 LYM9 11634.5 A 92.7888.06E−03 3 LYM138 12561.3 L 2.062 2.00E−05 71.7 LYM1 11602.1 A 92.6341.10E−02 2.9 LYM119 12461.4 L 2.016 4.40E−05 67.8 LYM17 11684.5 A 92.5391.23E−02 2.8 LYM119 12461.1 L 1.978 1.02E−04 64.7 LYM111 12251.3 A 92.441.48E−02 2.6 LYM130 12332.1 L 1.895 1.67E−04 57.8 LYM162 12234.4 A92.526 1.48E−02 2.7 LYM106 12142.2 L 1.969 3.33E−04 63.9 LYM4 11706.5 A92.404 1.58E−02 2.6 LYM119 12463.2 L 1.884 4.03E−04 56.8 LYM130 12333.1A 92.728 1.74E−02 3 LYM220 12851.8 L 1.88 5.61E−04 56.5 LYM143 12521.1 A92.355 1.77E−02 2.5 LYM174 12411.3 L 1.931 8.78E−04 60.7 LYM289 12491.4A 92.293 1.95E−02 2.5 LYM174 12412.1 L 1.831 1.48E−03 52.4 LYM14312523.4 A 92.243 2.22E−02 2.4 LYM289 12493.1 L 1.805 1.50E−03 50.2LYM130 12331.3 A 92.67 2.48E−02 2.9 LYM107 12632.3 L 1.799 2.47E−03 49.7LYM4 11706.3 A 92.134 2.66E−02 2.3 LYM153 12323.2 L 1.781 2.51E−03 48.2LYM290 12502.1 A 93.971 2.67E−02 4.3 LYM153 12324.1 L 1.798 2.61E−0349.7 LYM17 11683.1 A 93.189 2.71E−02 3.5 LYM119 12462.1 L 1.78 5.10E−0348.1 LYM17 11681.4 A 92.382 2.78E−02 2.6 LYM288 12743.9 L 1.704 5.72E−0341.9 LYM132 12275.1 A 92.086 2.93E−02 2.2 LYM255 13082.5 L 1.8265.79E−03 52 LYM268 12482.3 A 92.799 3.40E−02 3 LYM255 13082.8 L 1.6877.22E−03 40.4 LYM143 12524.7 A 92.003 3.43E−02 2.2 LYM288 12743.5 L1.745 8.60E−03 45.3 LYM16 11623.5 A 91.994 3.52E−02 2.1 LYM255 13082.7 L1.719 1.08E−02 43.1 LYM100 12131.3 A 93.235 3.92E−02 3.5 LYM153 12324.2L 1.661 1.28E−02 38.3 LYM141 12404.3 A 92.279 3.95E−02 2.5 LYM11912462.2 L 1.705 1.33E−02 42 LYM9 11633.7 A 91.968 4.61E−02 2.1 LYM10212222.2 L 1.642 1.38E−02 36.7 LYM16 11623.2 A 91.948 4.62E−02 2.1 LYM15212371.2 L 1.732 1.45E−02 44.2 LYM113 12441.4 A 91.832 4.82E−02 2 LYM10512293.1 L 1.648 1.48E−02 37.1 LYM16 11622.2 A 91.795 5.19E−02 1.9 LYM13712151.4 L 1.625 1.60E−02 35.3 LYM289 12491.1 A 92.554 5.47E−02 2.8LYM174 12411.2 L 1.651 1.70E−02 37.4 LYM174 12414.2 A 91.886 5.60E−02 2LYM289 12493.2 L 1.715 1.88E−02 42.8 LYM15 11612.3 A 92.3 6.55E−02 2.5LYM106 12144.4 L 1.588 2.45E−02 32.2 LYM143 12521.2 A 92.339 6.73E−022.5 LYM105 12295.2 L 1.594 2.68E−02 32.7 LYM22 11762.2 A 92.049 7.65E−022.2 LYM105 12297.2 L 1.591 2.80E−02 32.4 LYM148 12173.1 A 93.6237.77E−02 4 LYM130 12332.2 L 1.585 2.81E−02 31.9 LYM268 12483.4 A 92.117.91E−02 2.3 LYM130 12334.1 L 1.57 2.87E−02 30.7 LYM153 12323.2 A 92.0188.66E−02 2.2 LYM270 12873.6 L 1.558 4.30E−02 29.7 LYM129 12572.4 A95.426 8.79E−02 6 LYM111 12252.2 L 1.56 4.53E−02 29.8 LYM152 12373.1 A92.994 9.17E−02 3.3 LYM153 12321.2 L 1.566 4.59E−02 30.4 LYM16 11624.6 A91.607 9.39E−02 1.7 LYM137 12151.1 L 1.548 4.97E−02 28.8 LYM111 12251.1A 91.531 9.51E−02 1.6 LYM137 12151.2 L 1.543 6.15E−02 28.5 LYM10212222.3 A 91.611 1.04E−01 1.7 LYM105 12294.2 L 1.502 7.39E−02 25.1LYM152 12371.3 A 91.465 1.08E−01 1.6 LYM106 12144.3 L 1.531 7.99E−0227.4 LYM105 12293.1 A 92.855 1.10E−01 3.1 LYM138 12562.2 L 1.51 8.00E−0225.7 LYM148 12171.2 A 97.189 1.13E−01 7.9 LYM291 12754.9 L 1.5248.85E−02 26.8 LYM3 12041.2 A 91.82 1.20E−01 2 LYM130 12331.3 L 1.5849.07E−02 31.9 LYM290 12502.4 A 92.541 1.25E−01 2.8 LYM137 12154.5 L1.535 1.33E−01 27.8 LYM22 11762.1 A 91.581 1.28E−01 1.7 LYM143 12524.7 L1.504 1.44E−01 25.2 LYM268 12482.1 A 91.518 1.36E−01 1.6 LYM289 12492.2L 1.442 1.47E−01 20.1 LYM3 12043.1 A 92.154 1.37E−01 2.3 LYM102 12222.3L 1.44 1.55E−01 19.8 LYM111 12252.2 A 92.017 1.44E−01 2.2 LYM288 12741.9L 1.451 1.68E−01 20.8 LYM138 12561.3 A 91.741 1.49E−01 1.9 LYM17312981.6 L 1.427 1.71E−01 18.8 LYM148 12172.1 A 91.854 1.50E−01 2 LYM13712153.1 L 1.427 1.79E−01 18.8 LYM15 11611.3 A 91.282 1.57E−01 1.4 LYM13812564.1 L 1.432 1.94E−01 19.2 LYM134 12313.2 A 92.927 1.58E−01 3.2 LYM9012395.3 L 1.425 1.97E−01 18.6 LYM141 12404.2 A 92.666 1.60E−01 2.9LYM152 12371.3 L 1.439 2.02E−01 19.8 LYM15 11612.2 A 92.399 1.67E−01 2.6LYM212 13032.8 L 1.409 2.12E−01 17.3 LYM138 12561.1 A 91.667 1.72E−011.8 LYM288 12743.8 L 1.41 2.21E−01 17.4 LYM10 11741.2 A 93.084 1.84E−013.4 LYM111 12254.4 L 1.396 2.43E−01 16.2 LYM2 11693.3 A 91.311 1.94E−011.4 LYM197 12821.6 L 1.383 2.76E−01 15.1 LYM13 11772.1 A 91.162 1.96E−011.2 LYM242 13051.8 L 1.376 3.06E−01 14.6 LYM152 12371.2 A 94.0351.98E−01 4.4 LYM107 12631.4 L 1.367 3.11E−01 13.8 LYM141 12404.4 A91.382 2.00E−01 1.5 LYM242 13052.5 L 1.371 3.18E−01 14.1 LYM268 12483.2A 91.085 2.10E−01 1.1 LYM153 12322.1 L 1.356 3.52E−01 12.8 LYM29012502.2 A 91.245 2.10E−01 1.3 LYM106 12141.4 L 1.355 3.53E−01 12.8LYM132 12276.1 A 91.905 2.21E−01 2 LYM152 12373.1 L 1.354 3.59E−01 12.7LYM130 12332.1 A 91.423 2.26E−01 1.5 LYM107 12631.2 L 1.356 3.69E−0112.9 LYM137 12154.5 A 92.634 2.36E−01 2.9 LYM107 12631.1 L 1.3543.80E−01 12.7 LYM141 12402.4 A 92.747 2.36E−01 3 LYM102 12221.1 L 1.3513.82E−01 12.4 LYM13 11771.6 A 92.602 2.48E−01 2.8 LYM183 12994.8 L 1.3853.83E−01 15.3 LYM15 11614.3 A 90.956 2.69E−01 1 LYM105 12294.3 L 1.3214.64E−01 10 LYM22 11764.7 A 92.154 2.90E−01 2.3 LYM173 12981.5 L 1.324.93E−01 9.9 LYM132 12273.2 A 91.678 2.99E−01 1.8 LYM289 12491.4 L 1.3125.04E−01 9.2 LYM119 12462.1 A 92.884 2.99E−01 3.1 LYM102 12222.1 L 1.315.15E−01 9.1 LYM9 11633.2 A 92.37 3.05E−01 2.6 LYM255 13082.9 L 1.3145.16E−01 9.4 LYM1 11603.2 A 91.105 3.08E−01 1.2 LYM143 12524.5 L 1.3355.26E−01 11.1 LYM17 11682.1 A 91.575 3.09E−01 1.7 LYM289 12491.1 L 1.3055.32E−01 8.6 LYM19 11751.5 A 91.971 3.18E−01 2.1 LYM142 12802.9 L 1.3165.37E−01 9.5 LYM10 11744.1 A 90.973 3.22E−01 1 LYM100 12131.3 L 1.35.51E−01 8.2 LYM119 12463.2 A 91.619 3.27E−01 1.7 LYM102 12222.6 L 1.3035.63E−01 8.5 LYM16 11624.4 A 91.328 3.34E−01 1.4 LYM287 12774.6 L 1.2826.30E−01 6.7 LYM141 12404.1 A 90.894 3.38E−01 0.9 LYM130 12333.1 L 1.2746.78E−01 6 LYM19 11751.4 A 92.374 3.42E−01 2.6 LYM198 13005.8 L 1.2666.94E−01 5.4 LYM17 11684.4 A 91.321 3.42E−01 1.4 LYM183 12993.7 L 1.277.00E−01 5.7 LYM174 12411.3 A 90.996 3.43E−01 1 LYM106 12142.3 L 1.2657.00E−01 5.3 LYM105 12297.1 A 92.511 3.51E−01 2.7 LYM183 12994.7 L 1.2647.06E−01 5.3 LYM152 12372.2 A 91.633 3.54E−01 1.7 LYM201 12834.6 L 1.2617.14E−01 5 LYM153 12324.2 A 90.881 3.57E−01 0.9 LYM291 12753.6 L 1.2637.29E−01 5.1 LYM289 12493.6 A 90.791 3.59E−01 0.8 LYM287 12771.6 L 1.2587.30E−01 4.7 LYM130 12332.2 A 92.223 3.66E−01 2.4 LYM287 12773.7 L 1.2637.39E−01 5.1 LYM10 11744.5 A 93.031 3.89E−01 3.3 LYM212 13031.6 L 1.2557.40E−01 4.4 LYM143 12524.2 A 90.77 4.06E−01 0.8 LYM44 11885.4 L 1.2547.56E−01 4.4 LYM106 12141.4 A 90.774 4.06E−01 0.8 LYM212 13034.9 L 1.2677.63E−01 5.5 LYM21 11671.2 A 91.532 4.18E−01 1.6 LYM173 12982.6 L 1.238.61E−01 2.4 LYM290 12504.1 A 91.068 4.24E−01 1.1 LYM201 12833.7 L 1.2278.72E−01 2.2 LYM111 12254.4 A 91.031 4.40E−01 1.1 LYM44 11882.1 L 1.2099.64E−01 0.7 LYM119 12461.4 A 91.197 4.58E−01 1.3 LYM208 13012.5 L 1.2069.83E−01 0.4 LYM21 11673.1 A 91.387 4.60E−01 1.5 CONTROL — L 1.201 — 0LYM140 12262.3 A 91.389 4.61E−01 1.5 LYM138 12561.1 M 0.338 0.00E+00124.8 LYM148 12174.2 A 91.662 4.77E−01 1.8 LYM174 12414.3 M 0.2591.50E−05 72.8 LYM111 12254.3 A 91.161 4.82E−01 1.2 LYM138 12561.3 M0.258 2.00E−05 71.7 LYM138 12564.1 A 91.567 4.91E−01 1.7 LYM119 12461.4M 0.252 4.40E−05 67.8 LYM19 11754.1 A 90.586 5.02E−01 0.6 LYM119 12461.1M 0.247 1.02E−04 64.7 LYM119 12462.2 A 91.266 5.04E−01 1.3 LYM13012332.1 M 0.237 1.67E−04 57.8 LYM102 12222.2 A 91.356 5.05E−01 1.4LYM106 12142.2 M 0.246 3.33E−04 63.9 LYM105 12297.2 A 90.882 5.68E−010.9 LYM119 12463.2 M 0.235 4.03E−04 56.8 LYM119 12461.1 A 91.2255.83E−01 1.3 LYM220 12851.8 M 0.235 5.61E−04 56.5 LYM22 11764.1 A 91.3115.88E−01 1.4 LYM174 12411.3 M 0.241 8.78E−04 60.7 LYM22 11761.3 A 90.6216.14E−01 0.6 LYM174 12412.1 M 0.229 1.48E−03 52.4 LYM113 12442.1 A90.893 6.16E−01 0.9 LYM289 12493.1 M 0.226 1.50E−03 50.2 LYM134 12311.2A 90.868 6.23E−01 0.9 LYM107 12632.3 M 0.225 2.47E−03 49.7 LYM12912573.3 A 91.722 6.45E−01 1.8 LYM153 12323.2 M 0.223 2.51E−03 48.2LYM174 12414.3 A 90.625 6.59E−01 0.6 LYM153 12324.1 M 0.225 2.61E−0349.7 LYM10 11742.1 A 90.422 6.74E−01 0.4 LYM119 12462.1 M 0.222 5.10E−0348.1 LYM1 11601.1 A 90.906 6.83E−01 0.9 LYM288 12743.9 M 0.213 5.72E−0341.9 LYM290 12501.3 A 90.39 6.87E−01 0.4 LYM255 13082.5 M 0.228 5.79E−0352 LYM140 12261.2 A 91.222 6.93E−01 1.3 LYM255 13082.8 M 0.211 7.22E−0340.4 LYM3 12041.1 A 91.583 6.94E−01 1.7 LYM288 12743.5 M 0.218 8.60E−0345.3 LYM153 12321.2 A 90.616 7.11E−01 0.6 LYM255 13082.7 M 0.2151.08E−02 43.1 LYM148 12174.1 A 90.592 7.15E−01 0.6 LYM153 12324.2 M0.208 1.28E−02 38.3 LYM102 12221.1 A 90.466 7.40E−01 0.4 LYM119 12462.2M 0.213 1.33E−02 42 LYM140 12261.4 A 90.837 7.42E−01 0.9 LYM102 12222.2M 0.205 1.38E−02 36.7 LYM162 12234.3 A 90.909 7.49E−01 0.9 LYM15212371.2 M 0.217 1.45E−02 44.2 LYM132 12271.4 A 90.298 7.84E−01 0.3LYM105 12293.1 M 0.206 1.48E−02 37.1 LYM129 12572.2 A 90.907 7.96E−010.9 LYM137 12151.4 M 0.203 1.60E−02 35.3 LYM100 12134.1 A 90.8098.05E−01 0.8 LYM174 12411.2 M 0.206 1.70E−02 37.4 LYM19 11753.1 A 90.318.11E−01 0.3 LYM289 12493.2 M 0.214 1.88E−02 42.8 LYM289 12493.2 A90.591 8.24E−01 0.6 LYM106 12144.4 M 0.199 2.45E−02 32.2 LYM102 12222.6A 90.769 8.26E−01 0.8 LYM105 12295.2 M 0.199 2.68E−02 32.7 LYM10 11742.2A 90.507 8.27E−01 0.5 LYM105 12297.2 M 0.199 2.80E−02 32.4 LYM9 11632.1A 90.231 8.32E−01 0.2 LYM130 12332.2 M 0.198 2.81E−02 31.9 LYM11312444.5 A 90.243 8.32E−01 0.2 LYM130 12334.1 M 0.196 2.87E−02 30.7LYM102 12222.1 A 90.968 8.39E−01 1 LYM270 12873.6 M 0.195 4.30E−02 29.7LYM1 11604.4 A 90.574 8.76E−01 0.6 LYM111 12252.2 M 0.195 4.53E−02 29.8LYM3 12043.2 A 90.701 8.80E−01 0.7 LYM153 12321.2 M 0.196 4.59E−02 30.4LYM105 12294.3 A 90.228 8.91E−01 0.2 LYM137 12151.1 M 0.193 4.97E−0228.8 LYM153 12324.1 A 90.308 8.94E−01 0.3 LYM137 12151.2 M 0.1936.15E−02 28.5 LYM15 11614.4 A 90.158 9.00E−01 0.1 LYM105 12294.2 M 0.1887.39E−02 25.1 LYM13 11772.2 A 90.26 9.44E−01 0.2 LYM106 12144.3 M 0.1917.99E−02 27.4 LYM289 12492.2 A 90.234 9.48E−01 0.2 LYM138 12562.2 M0.189 8.00E−02 25.7 LYM162 12231.1 A 90.145 9.78E−01 0.1 LYM291 12754.9M 0.19 8.85E−02 26.8 CONTROL — A 90.061 — 0 LYM130 12331.3 M 0.1989.07E−02 31.9 LYM13 11771.6 B 0.272 1.17E−02 23.1 LYM107 12631.4 M 0.1821.23E−01 21.4 LYM129 12573.3 B 0.288 2.16E−02 30.2 LYM137 12154.5 M0.192 1.33E−01 27.8 LYM129 12573.5 B 0.364 2.30E−02 65 LYM153 12322.1 M0.181 1.40E−01 20.6 LYM4 11702.3 B 0.27 3.35E−02 22.3 LYM143 12524.7 M0.188 1.44E−01 25.2 LYM4 11701.1 B 0.259 4.26E−02 17.5 LYM289 12492.2 M0.18 1.47E−01 20.1 LYM152 12373.2 B 0.376 4.78E−02 70.4 LYM102 12222.3 M0.18 1.55E−01 19.8 LYM19 11752.2 B 0.255 5.74E−02 15.5 LYM288 12741.9 M0.181 1.68E−01 20.8 LYM15 11611.3 B 0.255 6.26E−02 15.5 LYM173 12981.6 M0.178 1.71E−01 18.8 LYM138 12561.1 B 0.261 6.50E−02 18.3 LYM137 12153.1M 0.178 1.79E−01 18.8 LYM17 11682.1 B 0.324 6.56E−02 46.9 LYM138 12564.1M 0.179 1.94E−01 19.2 LYM17 11683.1 B 0.266 6.67E−02 20.3 LYM90 12395.3M 0.178 1.97E−01 18.6 LYM130 12333.1 B 0.254 7.69E−02 15.2 LYM15212371.3 M 0.18 2.02E−01 19.8 LYM9 11633.7 B 0.301 9.51E−02 36.4 LYM21213032.8 M 0.176 2.12E−01 17.3 LYM148 12171.2 B 0.281 1.01E−01 27.4LYM288 12743.8 M 0.176 2.21E−01 17.4 LYM4 11706.3 B 0.316 1.05E−01 43.2LYM111 12254.4 M 0.175 2.43E−01 16.2 LYM4 11705.2 B 0.316 1.25E−01 43.1LYM197 12821.6 M 0.173 2.76E−01 15.1 LYM9 11632.2 B 0.339 1.56E−01 53.4LYM242 13051.8 M 0.172 3.06E−01 14.6 LYM2 11691.2 B 0.244 1.73E−01 10.4LYM242 13052.5 M 0.171 3.18E−01 14.1 LYM162 12234.4 B 0.299 2.06E−0135.3 LYM106 12141.4 M 0.169 3.53E−01 12.8 LYM148 12174.1 B 0.3152.13E−01 42.7 LYM152 12373.1 M 0.169 3.59E−01 12.7 LYM289 12493.2 B0.271 2.20E−01 22.9 LYM107 12631.2 M 0.169 3.69E−01 12.9 LYM9 11634.5 B0.26 2.39E−01 17.8 LYM107 12631.1 M 0.169 3.80E−01 12.7 LYM129 12571.3 B0.249 2.41E−01 12.7 LYM102 12221.1 M 0.169 3.82E−01 12.4 LYM153 12323.2B 0.259 2.51E−01 17.2 LYM183 12994.8 M 0.173 3.83E−01 15.3 LYM11912463.2 B 0.433 2.58E−01 95.9 LYM105 12294.3 M 0.165 4.64E−01 10 LYM13012331.3 B 0.239 2.71E−01 8.1 LYM173 12981.5 M 0.165 4.93E−01 9.9 LYM1911751.5 B 0.243 2.73E−01 9.8 LYM289 12491.4 M 0.164 5.04E−01 9.2 LYM1511612.3 B 0.289 2.83E−01 31.1 LYM102 12222.1 M 0.164 5.15E−01 9.1 LYM2111672.4 B 0.252 2.88E−01 14.1 LYM255 13082.9 M 0.164 5.16E−01 9.4 LYM1611624.4 B 0.251 3.28E−01 13.5 LYM143 12524.5 M 0.167 5.26E−01 11.1LYM129 12572.4 B 0.316 3.30E−01 43 LYM289 12491.1 M 0.163 5.32E−01 8.6LYM113 12442.1 B 0.326 3.53E−01 47.8 LYM142 12802.9 M 0.164 5.37E−01 9.5LYM4 11706.5 B 0.296 3.55E−01 33.9 LYM100 12131.3 M 0.162 5.51E−01 8.2LYM132 12275.1 B 0.289 3.63E−01 30.8 LYM102 12222.6 M 0.163 5.63E−01 8.5LYM129 12572.2 B 0.303 3.87E−01 37.3 LYM287 12774.6 M 0.16 6.30E−01 6.7LYM13 11773.2 B 0.314 3.98E−01 42.1 LYM130 12333.1 M 0.159 6.78E−01 6LYM143 12521.2 B 0.264 4.18E−01 19.7 LYM198 13005.8 M 0.158 6.94E−01 5.4LYM143 12523.4 B 0.274 4.27E−01 24.3 LYM183 12993.7 M 0.159 7.00E−01 5.7LYM113 12441.4 B 0.278 4.50E−01 25.7 LYM106 12142.3 M 0.158 7.00E−01 5.3LYM106 12141.4 B 0.254 4.54E−01 15.1 LYM183 12994.7 M 0.158 7.06E−01 5.3LYM13 11772.1 B 0.27 4.61E−01 22.3 LYM201 12834.6 M 0.158 7.14E−01 5LYM9 11632.1 B 0.319 4.74E−01 44.4 LYM291 12753.6 M 0.158 7.29E−01 5.1LYM111 12254.3 B 0.335 4.82E−01 51.7 LYM287 12771.6 M 0.157 7.30E−01 4.7LYM153 12324.2 B 0.304 4.85E−01 37.6 LYM287 12773.7 M 0.158 7.39E−01 5.1LYM106 12144.4 B 0.233 4.92E−01 5.6 LYM212 13031.6 M 0.157 7.40E−01 4.4LYM1 11602.1 B 0.236 4.95E−01 6.7 LYM270 12871.5 M 0.159 7.48E−01 5.7LYM130 12332.2 B 0.232 4.98E−01 5 LYM44 11885.4 M 0.157 7.56E−01 4.4LYM2 11695.3 B 0.251 5.12E−01 13.5 LYM212 13034.9 M 0.158 7.63E−01 5.5LYM141 12404.1 B 0.278 5.13E−01 25.7 LYM107 12632.1 M 0.156 7.80E−01 4LYM141 12402.4 B 0.243 5.22E−01 10.1 LYM173 12982.6 M 0.154 8.61E−01 2.4LYM16 11624.6 B 0.291 5.38E−01 31.9 LYM201 12833.7 M 0.153 8.72E−01 2.2LYM134 12311.2 B 0.289 5.54E−01 31.1 LYM44 11882.1 M 0.151 9.64E−01 0.7LYM111 12251.1 B 0.338 5.57E−01 53.1 LYM208 13012.5 M 0.151 9.83E−01 0.4LYM141 12404.4 B 0.261 5.64E−01 18 CONTROL — M 0.15 — 0 LYM17 11684.4 B0.23 5.76E−01 4.2 LYM138 12561.1 N 0.261 1.30E−05 49 LYM106 12142.1 B0.293 5.87E−01 32.8 LYM289 12493.1 N 0.234 7.05E−04 33.6 LYM134 12314.2B 0.241 6.43E−01 9.3 LYM174 12414.3 N 0.229 2.54E−03 30.8 LYM100 12131.3B 0.251 6.43E−01 13.8 LYM119 12461.1 N 0.227 3.16E−03 29.7 LYM10 11742.1B 0.267 6.69E−01 20.9 LYM138 12561.3 N 0.225 3.66E−03 28.5 LYM11112251.3 B 0.239 6.76E−01 8.4 LYM119 12461.4 N 0.224 5.01E−03 27.8 LYM11112252.2 B 0.229 6.87E−01 3.9 LYM174 12411.3 N 0.225 7.02E−03 28.9 LYM1611623.5 B 0.259 6.97E−01 17.2 LYM106 12142.2 N 0.226 8.45E−03 29.3LYM106 12142.2 B 0.233 6.99E−01 5.6 LYM153 12323.2 N 0.216 1.61E−02 23.5LYM148 12173.1 B 0.229 7.02E−01 3.6 LYM153 12324.1 N 0.217 1.92E−02 23.8LYM152 12373.1 B 0.229 7.02E−01 3.9 LYM119 12463.2 N 0.212 3.04E−02 21LYM134 12312.3 B 0.245 7.07E−01 11 LYM220 12851.8 N 0.212 3.13E−02 21.2LYM290 12504.1 B 0.283 7.08E−01 28 LYM289 12493.2 N 0.217 3.21E−02 24.2LYM16 11623.2 B 0.25 7.31E−01 13.2 LYM174 12412.1 N 0.214 3.22E−02 22.5LYM2 11695.1 B 0.277 7.60E−01 25.4 LYM137 12151.4 N 0.208 4.03E−02 19.1LYM162 12231.1 B 0.235 7.79E−01 6.4 LYM288 12743.5 N 0.213 4.24E−02 21.5LYM2 11692.3 B 0.251 7.87E−01 13.5 LYM105 12295.2 N 0.21 4.60E−02 19.9LYM113 12443.1 B 0.261 7.97E−01 18 LYM255 13082.8 N 0.21 5.20E−02 20.1LYM152 12372.2 B 0.235 8.07E−01 6.4 LYM119 12462.1 N 0.211 5.82E−02 20.8LYM143 12521.1 B 0.226 8.11E−01 2.5 LYM130 12332.1 N 0.207 5.93E−02 18.4LYM130 12334.1 B 0.259 8.16E−01 17.2 LYM107 12632.3 N 0.207 6.68E−0218.4 LYM153 12324.1 B 0.244 8.17E−01 10.7 LYM153 12324.2 N 0.2047.50E−02 16.6 LYM137 12154.5 B 0.226 8.28E−01 2.2 LYM119 12462.2 N 0.2087.54E−02 19 LYM15 11614.4 B 0.233 8.31E−01 5.3 LYM105 12293.1 N 0.2057.59E−02 17.3 LYM16 11622.2 B 0.233 8.34E−01 5.6 LYM152 12371.3 N 0.2057.65E−02 17.4 LYM289 12493.6 B 0.249 8.38E−01 12.7 LYM255 13082.7 N0.207 8.60E−02 18.1 LYM1 11604.4 B 0.234 8.63E−01 6.2 LYM111 12252.2 N0.203 9.29E−02 16.2 LYM289 12491.1 B 0.235 8.75E−01 6.4 LYM102 12222.2 N0.202 1.09E−01 15.6 LYM21 11673.1 B 0.226 8.75E−01 2.5 LYM255 13082.5 N0.207 1.17E−01 18.2 LYM132 12271.4 B 0.229 9.38E−01 3.6 LYM137 12151.2 N0.204 1.18E−01 16.5 LYM1 11603.2 B 0.222 9.68E−01 0.5 LYM106 12144.4 N0.199 1.21E−01 14 LYM138 12561.3 B 0.223 9.70E−01 0.8 LYM143 12524.7 N0.204 1.42E−01 16.6 LYM152 12371.2 B 0.221 9.92E−01 0.2 LYM288 12743.9 N0.198 1.48E−01 13.3 CONTROL — B 0.221 — 0 LYM153 12321.2 N 0.1981.63E−01 13.4 LYM9 11632.2 C 3.269 4.30E−05 64 LYM152 12371.2 N 0.2041.67E−01 16.5 LYM4 11705.2 C 2.993 1.48E−04 50.1 LYM105 12294.2 N 0.1961.85E−01 11.8 LYM17 11682.1 C 2.731 8.43E−04 37 LYM153 12322.1 N 0.1961.90E−01 11.8 LYM4 11706.3 C 3.394 2.46E−03 70.2 LYM105 12297.2 N 0.1961.90E−01 11.9 LYM129 12573.3 C 3.106 2.83E−03 55.8 LYM137 12151.1 N0.196 2.05E−01 11.8 LYM130 12333.1 C 2.681 3.58E−03 34.5 LYM142 12804.1N 0.198 2.08E−01 13.3 LYM4 11702.3 C 3.1 4.05E−03 55.5 LYM152 12373.1 N0.196 2.17E−01 11.8 LYM138 12561.1 C 2.531 5.20E−03 27 LYM174 12411.2 N0.196 2.21E−01 12.1 LYM13 11771.6 C 2.756 6.82E−03 38.3 LYM197 12821.6 N0.194 2.27E−01 10.6 LYM15 11612.3 C 2.494 7.56E−03 25.1 LYM130 12334.1 N0.193 2.39E−01 10.3 LYM9 11634.5 C 2.631 1.39E−02 32 LYM102 12222.3 N0.193 2.51E−01 10.3 LYM129 12573.5 C 3.519 1.43E−02 76.5 LYM130 12332.2N 0.191 3.09E−01 9.2 LYM17 11683.1 C 2.394 2.12E−02 20.1 LYM291 12754.9N 0.194 3.10E−01 10.7 LYM129 12571.3 C 2.763 2.21E−02 38.6 LYM10612144.3 N 0.192 3.17E−01 9.9 LYM106 12144.4 C 2.406 2.27E−02 20.7 LYM27012873.6 N 0.19 3.42E−01 8.7 LYM19 11751.5 C 2.356 3.15E−02 18.2 LYM10212222.1 N 0.19 3.58E−01 8.6 LYM4 11701.1 C 2.844 3.92E−02 42.6 LYM10212221.1 N 0.188 3.97E−01 7.6 LYM113 12441.4 C 2.644 4.19E−02 32.6 LYM13712153.1 N 0.188 3.97E−01 7.7 LYM17 11684.4 C 2.356 5.63E−02 18.2 LYM17312981.6 N 0.188 3.98E−01 7.7 LYM129 12572.4 C 3.038 5.70E−02 52.4 LYM9012395.3 N 0.189 4.04E−01 8.2 LYM15 11611.3 C 2.3 5.79E−02 15.4 LYM10712631.2 N 0.189 4.08E−01 8.1 LYM119 12463.2 C 3.419 8.18E−02 71.5 LYM4411882.1 N 0.188 4.49E−01 7.4 LYM1 11602.1 C 2.281 8.53E−02 14.4 LYM17312981.5 N 0.187 4.84E−01 6.6 LYM148 12171.2 C 2.375 1.08E−01 19.1 LYM14312524.5 N 0.189 5.07E−01 7.9 LYM152 12373.2 C 2.775 1.08E−01 39.2 LYM24213052.5 N 0.186 5.08E−01 6.2 LYM4 11706.5 C 3.069 1.20E−01 53.9 LYM13012331.3 N 0.189 5.20E−01 8.2 LYM9 11633.7 C 3.063 1.26E−01 53.6 LYM28812743.8 N 0.185 5.30E−01 6 LYM106 12144.3 C 2.244 1.58E−01 12.6 LYM13812564.1 N 0.185 5.54E−01 5.8 LYM141 12402.4 C 2.381 1.63E−01 19.4 LYM28912492.2 N 0.184 5.60E−01 5.3 LYM16 11624.4 C 2.425 1.90E−01 21.6 LYM13712154.5 N 0.186 5.68E−01 6.4 LYM13 11773.2 C 2.619 1.93E−01 31.4 LYM13812562.2 N 0.183 6.21E−01 4.8 LYM106 12142.2 C 2.3 1.99E−01 15.4 LYM28912491.4 N 0.182 6.68E−01 3.8 LYM137 12154.5 C 2.3 1.99E−01 15.4 LYM10612141.4 N 0.181 6.80E−01 3.6 LYM132 12275.1 C 2.275 2.02E−01 14.1 LYM18312994.7 N 0.181 6.90E−01 3.7 LYM153 12323.2 C 2.481 2.07E−01 24.5 LYM10712631.4 N 0.181 6.97E−01 3.5 LYM9 11633.2 C 2.356 2.33E−01 18.2 LYM28912491.1 N 0.18 7.34E−01 3 LYM134 12314.2 C 2.288 2.41E−01 14.7 LYM27012871.8 N 0.181 7.36E−01 3.7 LYM129 12572.2 C 3 2.69E−01 50.5 LYM14212804.3 N 0.181 7.40E−01 3.7 LYM134 12312.3 C 2.2 2.70E−01 10.4 LYM24213051.8 N 0.18 7.41E−01 3 LYM113 12442.1 C 2.681 2.75E−01 34.5 LYM4411885.3 N 0.181 7.62E−01 3.2 LYM13 11772.1 C 2.481 2.80E−01 24.5 LYM18312994.8 N 0.181 7.66E−01 3.7 LYM148 12173.1 C 2.15 2.91E−01 7.8 LYM10612142.3 N 0.179 7.88E−01 2.4 LYM119 12461.1 C 2.288 2.95E−01 14.7 LYM11112254.4 N 0.179 7.89E−01 2.4 LYM13 11771.9 C 2.194 2.97E−01 10 LYM10712631.1 N 0.179 7.99E−01 2.4 LYM141 12404.1 C 2.444 3.06E−01 22.6 LYM20112834.6 N 0.179 8.18E−01 2.2 LYM16 11624.6 C 2.688 3.41E−01 34.8 LYM10012131.3 N 0.178 8.46E−01 1.7 LYM148 12174.1 C 2.425 3.45E−01 21.6 LYM21213032.8 N 0.178 8.59E−01 1.6 LYM16 11622.2 C 2.194 3.53E−01 10 LYM20112833.9 N 0.177 8.96E−01 1.1 LYM9 11632.1 C 3.006 3.58E−01 50.8 LYM27012871.5 N 0.178 9.11E−01 1.5 LYM130 12331.3 C 2.219 3.60E−01 11.3 LYM10512294.3 N 0.177 9.14E−01 1 LYM153 12324.2 C 2.469 3.65E−01 23.8 LYM10712632.1 N 0.177 9.15E−01 1 LYM16 11623.2 C 2.413 3.71E−01 21 LYM20112833.7 N 0.176 9.24E−01 0.8 LYM162 12234.4 C 2.5 3.76E−01 25.4 LYM13712152.1 N 0.176 9.43E−01 0.7 LYM111 12254.3 C 2.581 4.18E−01 29.5 LYM20813012.5 N 0.176 9.69E−01 0.5 LYM111 12251.1 C 2.688 4.40E−01 34.8 LYM19712824.4 N 0.176 9.72E−01 0.3 LYM17 11681.4 C 2.115 4.53E−01 6.1 LYM28812744.6 N 0.176 9.74E−01 0.4 LYM15 11614.4 C 2.125 4.67E−01 6.6 CONTROL— N 0.175 — 0 LYM106 12142.1 C 2.531 4.74E−01 27 LYM174 12414.3 O 2.0941.00E−06 72.1 LYM106 12141.4 C 2.358 4.96E−01 18.3 LYM288 12743.9 O 1.733.30E−05 42.2 LYM143 12521.2 C 2.181 5.05E−01 9.4 LYM255 13082.8 O 1.7124.70E−05 40.7 LYM19 11752.2 C 2.081 5.38E−01 4.4 LYM106 12144.4 O 1.6242.04E−04 33.5 LYM162 12231.3 C 2.106 5.41E−01 5.7 LYM270 12873.6 O 1.5874.90E−04 30.4 LYM111 12251.3 C 2.35 5.87E−01 17.9 LYM289 12492.2 O 1.5181.30E−03 24.7 LYM141 12404.4 C 2.169 6.33E−01 8.8 LYM105 12294.2 O 1.4961.87E−03 22.9 LYM137 12151.2 C 2.058 6.54E−01 3.2 LYM107 12631.4 O 1.4872.26E−03 22.2 LYM111 12254.4 C 2.181 6.62E−01 9.4 LYM130 12332.1 O 1.9283.71E−03 58.5 LYM16 11623.5 C 2.281 6.77E−01 14.4 LYM153 12323.2 O 1.8284.86E−03 50.3 LYM153 12324.1 C 2.181 6.83E−01 9.4 LYM130 12334.1 O 1.5785.52E−03 29.7 LYM138 12561.3 C 2.175 6.87E−01 9.1 LYM137 12153.1 O 1.4357.32E−03 17.9 LYM2 11695.3 C 2.05 6.93E−01 2.8 LYM153 12324.2 O 1.6897.63E−03 38.9 LYM137 12151.1 C 2.05 7.06E−01 2.8 LYM173 12981.6 O 1.4638.10E−03 20.2 LYM143 12523.4 C 2.156 7.37E−01 8.2 LYM138 12561.1 O 2.7268.93E−03 124.1 LYM2 11695.1 C 2.5 7.66E−01 25.4 LYM153 12322.1 O 1.4329.89E−03 17.7 LYM2 11691.2 C 2.075 7.88E−01 4.1 LYM289 12493.1 O 1.8181.07E−02 49.5 LYM21 11672.4 C 2.031 7.89E−01 1.9 LYM119 12461.4 O 2.031.16E−02 66.9 LYM137 12152.1 C 2.063 7.91E−01 3.5 LYM102 12222.2 O 1.6761.46E−02 37.7 LYM130 12332.2 C 2.031 8.44E−01 1.9 LYM102 12222.3 O 1.4551.94E−02 19.6 LYM162 12231.1 C 2.125 8.45E−01 6.6 LYM105 12297.2 O 1.5982.07E−02 31.3 LYM134 12311.2 C 2.081 8.49E−01 4.4 LYM107 12631.2 O 1.3862.27E−02 14 LYM290 12504.1 C 2.15 8.69E−01 7.8 LYM138 12561.3 O 2.0663.41E−02 69.8 LYM162 12234.3 C 2.031 9.11E−01 1.9 LYM119 12461.1 O 1.9486.22E−02 60.1 LYM137 12153.1 C 2.013 9.23E−01 1 LYM105 12293.1 O 1.6956.63E−02 39.3 LYM152 12373.1 C 2.006 9.33E−01 0.6 LYM106 12141.4 O 1.3887.61E−02 14.1 LYM152 12371.2 C 2 9.69E−01 0.3 LYM212 13032.8 O 1.4497.79E−02 19.1 LYM10 11742.1 C 2.013 9.70E−01 1 LYM119 12463.2 O 1.9178.15E−02 57.6 LYM17 11684.5 C 2.006 9.72E−01 0.6 LYM105 12295.2 O 1.6078.74E−02 32.1 LYM289 12491.1 C 2 9.93E−01 0.3 LYM173 12982.6 O 1.3328.92E−02 9.5 CONTROL — C 1.994 — 0 LYM111 12254.4 O 1.43 9.17E−02 17.6LYM148 12171.2 D 0.362 3.00E−06 59.2 LYM174 12411.2 O 1.724 1.04E−0141.7 LYM143 12524.7 D 0.344 1.40E−05 51.3 LYM220 12851.8 O 1.8861.22E−01 55 LYM1 11602.1 D 0.313 8.90E−05 37.7 LYM105 12294.3 O 1.3561.28E−01 11.4 LYM130 12333.1 D 0.309 1.24E−04 36 LYM137 12151.4 O 1.6331.38E−01 34.2 LYM10 11744.1 D 0.301 2.98E−04 32.6 LYM174 12412.1 O 1.8471.64E−01 51.8 LYM10 11741.2 D 0.382 3.43E−04 67.9 LYM106 12142.2 O 1.9841.65E−01 63.1 LYM162 12234.3 D 0.299 4.64E−04 31.4 LYM130 12332.2 O1.615 1.74E−01 32.8 LYM102 12222.2 D 0.292 6.30E−04 28.6 LYM242 13051.8O 1.415 1.75E−01 16.3 LYM15 11614.3 D 0.291 7.21E−04 28 LYM107 12632.3 O1.846 1.82E−01 51.7 LYM140 12262.3 D 0.29 7.39E−04 27.5 LYM152 12373.1 O1.378 2.05E−01 13.2 LYM4 11706.5 D 0.289 8.21E−04 27 LYM137 12151.1 O1.582 2.07E−01 30 LYM105 12293.1 D 0.298 8.36E−04 31 LYM153 12324.1 O1.775 2.09E−01 45.9 LYM1 11602.6 D 0.406 1.24E−03 78.7 LYM119 12462.1 O1.851 2.26E−01 52.1 LYM152 12372.2 D 0.286 1.76E−03 26 LYM138 12562.2 O1.512 2.27E−01 24.3 LYM132 12273.2 D 0.283 1.88E−03 24.6 LYM289 12491.1O 1.328 2.38E−01 9.1 LYM132 12271.4 D 0.275 3.78E−03 20.8 LYM174 12411.3O 1.942 2.45E−01 59.6 LYM17 11684.4 D 0.271 1.10E−02 19.2 LYM137 12151.2O 1.587 2.45E−01 30.4 LYM119 12461.4 D 0.273 1.11E−02 20 LYM111 12252.2O 1.546 2.55E−01 27.1 LYM162 12231.3 D 0.278 1.15E−02 22.4 LYM28812743.8 O 1.464 2.62E−01 20.4 LYM13 11771.6 D 0.262 2.00E−02 15.2 LYM28712774.6 O 1.303 2.70E−01 7.1 LYM9 11632.2 D 0.261 2.89E−02 15 LYM28812743.5 O 1.78 2.75E−01 46.3 LYM119 12463.2 D 0.285 4.01E−02 25.5 LYM24213052.5 O 1.365 2.99E−01 12.2 LYM141 12404.2 D 0.255 4.81E−02 12.1LYM107 12631.1 O 1.407 3.08E−01 15.7 LYM138 12561.1 D 0.328 5.35E−0244.5 LYM100 12131.3 O 1.36 3.20E−01 11.7 LYM19 11751.5 D 0.291 5.76E−0228 LYM289 12491.4 O 1.322 3.20E−01 8.7 LYM19 11753.1 D 0.274 6.46E−0220.5 LYM90 12395.3 O 1.443 3.34E−01 18.6 LYM289 12493.6 D 0.253 7.62E−0211.2 LYM102 12222.1 O 1.339 3.34E−01 10.1 LYM268 12483.2 D 0.2567.90E−02 12.7 LYM197 12821.6 O 1.385 3.37E−01 13.8 LYM129 12573.5 D0.251 8.16E−02 10.4 LYM255 13082.7 O 1.711 3.37E−01 40.7 LYM148 12174.1D 0.303 8.57E−02 33.3 LYM119 12462.2 O 1.688 3.41E−01 38.8 LYM28912493.2 D 0.31 1.00E−01 36.3 LYM152 12371.2 O 1.791 3.57E−01 47.2 LYM911632.1 D 0.344 1.06E−01 51.2 LYM153 12321.2 O 1.545 3.58E−01 27 LYM111604.4 D 0.321 1.12E−01 41.4 LYM287 12771.6 O 1.284 3.68E−01 5.5 LYM1011742.2 D 0.303 1.26E−01 33.2 LYM289 12493.2 O 1.752 3.69E−01 44 LYM111603.2 D 0.28 1.48E−01 23 LYM106 12144.3 O 1.544 3.75E−01 26.9 LYM11912462.2 D 0.361 1.51E−01 58.8 LYM255 13082.5 O 1.81 3.83E−01 48.8 LYM14312521.1 D 0.259 1.56E−01 14.1 LYM288 12741.9 O 1.479 4.12E−01 21.6 LYM1711681.4 D 0.249 1.61E−01 9.6 LYM138 12564.1 O 1.452 4.26E−01 19.3 LYM1311772.1 D 0.248 1.66E−01 9.1 LYM291 12754.9 O 1.538 4.35E−01 26.4 LYM11912462.1 D 0.298 1.76E−01 31.1 LYM102 12221.1 O 1.353 4.81E−01 11.2 LYM1511612.2 D 0.263 1.80E−01 15.8 LYM152 12371.3 O 1.448 4.88E−01 19 LYM10212221.1 D 0.244 1.81E−01 7.3 LYM255 13082.9 O 1.356 5.04E−01 11.5 LYM17412411.2 D 0.304 1.83E−01 33.9 LYM130 12331.3 O 1.589 5.44E−01 30.6 LYM1611624.4 D 0.244 1.94E−01 7.2 LYM212 13031.6 O 1.272 5.47E−01 4.5 LYM2111673.1 D 0.26 1.96E−01 14.4 LYM143 12524.7 O 1.492 5.72E−01 22.7 LYM1711684.5 D 0.242 2.39E−01 6.4 LYM173 12981.5 O 1.331 5.74E−01 9.4 LYM13812561.3 D 0.321 2.41E−01 41.1 LYM106 12142.3 O 1.267 5.74E−01 4.2 LYM411705.2 D 0.273 2.47E−01 20.2 LYM142 12802.9 O 1.38 5.91E−01 13.4 LYM13812562.1 D 0.242 2.58E−01 6.5 LYM198 13005.8 O 1.273 5.92E−01 4.6 LYM14112404.3 D 0.274 2.69E−01 20.7 LYM102 12222.6 O 1.345 6.01E−01 10.5 LYM1711683.1 D 0.242 2.69E−01 6.3 LYM137 12154.5 O 1.544 6.05E−01 26.9 LYM1911754.1 D 0.261 2.73E−01 15 LYM201 12834.6 O 1.287 7.03E−01 5.8 LYM15212371.2 D 0.271 2.75E−01 19.3 LYM183 12994.8 O 1.414 7.10E−01 16.2LYM130 12334.1 D 0.245 2.83E−01 7.7 LYM44 11885.4 O 1.282 7.27E−01 5.4LYM134 12311.2 D 0.284 3.00E−01 25 LYM242 13053.7 O 1.262 7.36E−01 3.7LYM141 12402.4 D 0.296 3.09E−01 30.2 LYM107 12632.1 O 1.289 7.44E−01 5.9LYM2 11692.3 D 0.242 3.13E−01 6.6 LYM291 12753.6 O 1.292 7.51E−01 6.2LYM9 11633.7 D 0.277 3.20E−01 22 LYM143 12524.5 O 1.366 7.58E−01 12.2LYM19 11751.4 D 0.292 3.24E−01 28.3 LYM201 12833.7 O 1.241 7.73E−01 2LYM162 12231.1 D 0.279 3.32E−01 22.6 LYM130 12333.1 O 1.294 7.92E−01 6.4LYM148 12173.1 D 0.289 3.33E−01 27.2 LYM287 12773.7 O 1.293 8.02E−01 6.2LYM143 12524.2 D 0.263 3.48E−01 15.6 LYM183 12993.7 O 1.278 8.25E−01 5LYM15 11612.3 D 0.285 3.59E−01 25.4 LYM270 12871.5 O 1.292 8.85E−01 6.2LYM289 12491.1 D 0.281 3.79E−01 23.7 LYM183 12994.7 O 1.24 8.96E−01 2LYM130 12332.2 D 0.274 3.79E−01 20.6 LYM212 13034.9 O 1.27 9.25E−01 4.4LYM174 12414.3 D 0.313 3.80E−01 37.5 LYM208 13012.5 O 1.249 9.35E−01 2.7LYM100 12133.1 D 0.252 3.84E−01 10.8 CONTROL — O 1.217 — 0 LYM14112404.4 D 0.27 3.96E−01 18.9 LYM289 12493.1 P 2.457 6.00E−06 34.4 LYM16212234.4 D 0.307 4.01E−01 35 LYM153 12323.2 P 2.348 3.90E−05 28.5 LYM2111671.2 D 0.252 4.34E−01 11.1 LYM138 12561.1 P 2.896 4.80E−05 58.4 LYM1511611.3 D 0.286 4.64E−01 25.9 LYM288 12743.9 P 2.278 1.08E−04 24.6 LYM1011744.5 D 0.263 4.65E−01 15.5 LYM106 12144.4 P 2.162 1.09E−03 18.3LYM174 12412.1 D 0.283 4.68E−01 24.5 LYM130 12334.1 P 2.123 1.12E−0316.2 LYM174 12411.3 D 0.259 4.73E−01 13.9 LYM105 12297.2 P 2.1231.13E−03 16.1 LYM289 12491.4 D 0.25 4.85E−01 9.9 LYM173 12981.6 P 2.0882.27E−03 14.2 LYM113 12442.1 D 0.235 5.12E−01 3.6 LYM105 12293.1 P 2.2523.65E−03 23.2 LYM143 12521.2 D 0.244 5.14E−01 7.1 LYM105 12294.2 P 2.0613.93E−03 12.8 LYM102 12222.3 D 0.274 5.18E−01 20.7 LYM137 12153.1 P2.057 4.42E−03 12.5 LYM111 12251.1 D 0.264 5.22E−01 16.1 LYM197 12821.6P 2.058 4.44E−03 12.6 LYM17 11682.1 D 0.272 5.33E−01 19.6 LYM138 12561.3P 2.487 6.03E−03 36.1 LYM268 12483.4 D 0.258 5.50E−01 13.3 LYM10712631.4 P 2.034 7.95E−03 11.3 LYM21 11672.4 D 0.265 5.55E−01 16.5 LYM10212222.3 P 2.079 9.12E−03 13.8 LYM290 12502.4 D 0.255 6.03E−01 12.4LYM111 12254.4 P 2.013 1.74E−02 10.1 LYM268 12482.3 D 0.239 6.08E−01 5.1LYM102 12222.1 P 2.019 1.77E−02 10.5 LYM290 12501.3 D 0.242 6.70E−01 6.6LYM106 12141.4 P 1.999 1.86E−02 9.4 LYM105 12294.2 D 0.263 7.15E−01 15.6LYM119 12463.2 P 2.427 2.00E−02 32.8 LYM100 12131.3 D 0.246 7.22E−01 8.2LYM153 12322.1 P 2.025 2.34E−02 10.8 LYM111 12252.2 D 0.252 7.44E−0110.7 LYM270 12873.6 P 2.19 2.39E−02 19.8 LYM1 11601.1 D 0.241 7.48E−016.1 LYM102 12222.2 P 2.26 2.62E−02 23.6 LYM22 11762.1 D 0.236 7.59E−013.6 LYM137 12151.4 P 2.247 2.89E−02 22.9 LYM148 12172.1 D 0.251 7.85E−0110.2 LYM174 12414.3 P 2.533 2.94E−02 38.6 LYM268 12482.1 D 0.2438.20E−01 6.9 LYM212 13032.8 P 2.004 3.00E−02 9.6 LYM137 12153.1 D 0.248.22E−01 5.4 LYM152 12373.1 P 2.094 4.88E−02 14.6 LYM10 11742.1 D 0.2438.33E−01 7.1 LYM102 12221.1 P 1.969 5.91E−02 7.7 LYM162 12233.2 D 0.2368.50E−01 3.7 LYM119 12461.4 P 2.483 6.35E−02 35.8 LYM140 12261.4 D 0.2348.56E−01 2.9 LYM130 12332.2 P 2.183 6.35E−02 19.5 LYM290 12502.1 D 0.2348.96E−01 3.1 LYM153 12324.2 P 2.207 6.58E−02 20.7 LYM143 12523.4 D 0.2329.21E−01 1.9 LYM289 12492.2 P 2.063 6.71E−02 12.8 LYM9 11633.2 D 0.239.45E−01 1.4 LYM173 12982.6 P 1.944 7.81E−02 6.4 LYM111 12254.4 D 0.2289.48E−01 0.3 LYM289 12493.2 P 2.307 8.42E−02 26.2 LYM152 12373.2 D 0.2279.98E−01 0 LYM137 12151.1 P 2.145 9.13E−02 17.3 CONTROL — D 0.227 — 0LYM220 12851.8 P 2.294 9.18E−02 25.5 LYM4 11706.5 E 8.938 2.20E−05 18.6LYM100 12131.3 P 2.001 1.04E−01 9.5 LYM102 12222.2 E 8.875 3.70E−05 17.8LYM130 12332.1 P 2.437 1.12E−01 33.4 LYM119 12462.2 E 8.866 3.80E−0517.7 LYM119 12461.1 P 2.383 1.15E−01 30.4 LYM138 12561.1 E 8.8134.40E−05 16.9 LYM242 13051.8 P 2.011 1.19E−01 10 LYM10 11742.2 E 8.6889.10E−05 15.3 LYM288 12743.5 P 2.299 1.24E−01 25.8 LYM105 12293.1 E8.563 2.01E−04 13.6 LYM106 12142.2 P 2.411 1.25E−01 31.9 LYM152 12372.2E 8.563 2.01E−04 13.6 LYM105 12295.2 P 2.243 1.29E−01 22.7 LYM1 11602.6E 9.125 7.59E−04 21.1 LYM105 12294.3 P 1.953 1.30E−01 6.9 LYM19 11753.1E 8.313 1.23E−03 10.3 LYM107 12631.2 P 2.022 1.32E−01 10.7 LYM1 11603.2E 8.25 1.75E−03 9.5 LYM153 12324.1 P 2.309 1.37E−01 26.3 LYM10 11744.1 E8.125 4.92E−03 7.8 LYM174 12412.1 P 2.359 1.38E−01 29.1 LYM130 12333.1 E8.375 9.64E−03 11.1 LYM174 12411.2 P 2.258 1.41E−01 23.5 LYM132 12271.4E 8.375 9.64E−03 11.1 LYM242 13052.5 P 2.002 1.43E−01 9.5 LYM174 12414.3E 8.375 9.64E−03 11.1 LYM107 12632.3 P 2.326 1.47E−01 27.2 LYM10 11741.2E 9.063 1.38E−02 20.3 LYM106 12144.3 P 2.131 1.69E−01 16.6 LYM13012332.2 E 8.688 2.64E−02 15.3 LYM174 12411.3 P 2.458 1.72E−01 34.5LYM130 12334.1 E 8.688 2.64E−02 15.3 LYM212 13031.6 P 1.969 1.78E−01 7.7LYM141 12402.4 E 8.688 2.64E−02 15.3 LYM152 12371.3 P 2.06 1.86E−01 12.7LYM113 12442.1 E 7.938 3.53E−02 5.3 LYM255 13082.8 P 2.312 2.00E−01 26.5LYM9 11632.1 E 8.438 4.54E−02 12 LYM153 12321.2 P 2.11 2.02E−01 15.4LYM143 12524.7 E 9 4.73E−02 19.4 LYM119 12462.1 P 2.418 2.08E−01 32.3LYM132 12275.1 E 7.875 5.28E−02 4.5 LYM242 13053.7 P 1.914 2.14E−01 4.7LYM9 11633.7 E 7.875 5.28E−02 4.5 LYM288 12743.8 P 2.072 2.20E−01 13.4LYM17 11681.4 E 7.917 5.73E−02 5.1 LYM289 12491.1 P 1.959 2.38E−01 7.2LYM100 12133.1 E 8.313 6.24E−02 10.3 LYM111 12252.2 P 2.148 2.40E−0117.5 LYM119 12461.4 E 8.313 6.24E−02 10.3 LYM255 13082.9 P 1.9982.41E−01 9.3 LYM21 11672.4 E 8 6.71E−02 6.2 LYM119 12462.2 P 2.2182.61E−01 21.3 LYM17 11684.4 E 8.188 8.91E−02 8.6 LYM137 12151.2 P 2.2122.66E−01 21 LYM19 11751.5 E 8.188 8.91E−02 8.6 LYM289 12491.4 P 1.9252.70E−01 5.3 LYM143 12524.2 E 7.813 1.19E−01 3.7 LYM107 12631.1 P 1.9982.73E−01 9.3 LYM15 11614.3 E 7.813 1.19E−01 3.7 LYM106 12142.3 P 1.9312.87E−01 5.6 LYM148 12171.2 E 8.063 1.33E−01 7 LYM138 12562.2 P 2.0443.08E−01 11.8 LYM162 12231.3 E 8.063 1.33E−01 7 LYM255 13082.5 P 2.273.12E−01 24.2 LYM19 11754.1 E 8.063 1.33E−01 7 LYM255 13082.7 P 2.2093.30E−01 20.9 LYM141 12404.2 E 7.875 1.45E−01 4.5 LYM152 12371.2 P 2.2833.57E−01 24.9 LYM289 12491.4 E 7.875 1.45E−01 4.5 LYM90 12395.3 P 2.0413.80E−01 11.7 LYM119 12463.2 E 8.25 1.49E−01 9.5 LYM287 12771.6 P 1.8783.99E−01 2.8 LYM289 12493.2 E 8.25 1.49E−01 9.5 LYM107 12632.1 P 1.9444.04E−01 6.4 LYM162 12234.3 E 8.438 1.63E−01 12 LYM102 12222.6 P 1.9424.04E−01 6.2 LYM148 12174.1 E 8.625 1.74E−01 14.5 LYM288 12741.9 P 2.044.14E−01 11.6 LYM140 12262.3 E 7.75 1.85E−01 2.8 LYM138 12564.1 P 2.0494.46E−01 12.1 LYM3 12042.1 E 7.75 1.85E−01 2.8 LYM291 12754.9 P 2.0774.54E−01 13.7 LYM15 11611.3 E 8.479 1.89E−01 12.5 LYM287 12774.6 P 1.8994.58E−01 3.9 LYM141 12404.4 E 8.313 1.97E−01 10.3 LYM173 12981.5 P 1.9594.85E−01 7.2 LYM162 12234.4 E 8.438 2.63E−01 12 LYM130 12331.3 P 2.1334.95E−01 16.7 LYM289 12493.6 E 8 2.66E−01 6.2 LYM137 12154.5 P 2.0955.07E−01 14.6 LYM290 12502.4 E 8 2.66E−01 6.2 LYM201 12834.6 P 1.975.14E−01 7.8 LYM174 12411.2 E 8.688 2.73E−01 15.3 LYM143 12524.7 P 2.0885.44E−01 14.2 LYM290 12501.3 E 8.25 2.78E−01 9.5 LYM201 12833.9 P 1.8645.52E−01 2 LYM1 11604.4 E 8.063 3.07E−01 7 LYM142 12802.9 P 1.9315.89E−01 5.7 LYM21 11673.1 E 8.063 3.07E−01 7 LYM201 12833.7 P 1.8836.03E−01 3 LYM17 11683.1 E 7.75 3.22E−01 2.8 LYM183 12994.8 P 2.0066.56E−01 9.7 LYM2 11692.3 E 7.75 3.22E−01 2.8 LYM100 12133.3 P 1.8536.64E−01 1.4 LYM119 12462.1 E 8.688 3.33E−01 15.3 LYM130 12333.1 P 1.9136.70E−01 4.7 LYM141 12404.3 E 8.125 3.36E−01 7.8 LYM143 12524.5 P 1.996.99E−01 8.9 LYM102 12222.3 E 8.438 3.42E−01 12 LYM291 12753.6 P 1.8937.11E−01 3.6 LYM289 12491.1 E 8.75 3.45E−01 16.1 LYM142 12804.1 P 1.9017.24E−01 4 LYM137 12153.1 E 7.813 3.45E−01 3.7 LYM143 12521.1 P 1.8487.39E−01 1.1 LYM143 12521.1 E 7.813 3.45E−01 3.7 LYM44 11885.4 P 1.8647.91E−01 2 LYM21 11671.2 E 8.188 3.58E−01 8.6 LYM270 12871.8 P 1.9068.00E−01 4.3 LYM17 11682.1 E 7.938 3.99E−01 5.3 LYM270 12871.5 P 1.948.20E−01 6.1 LYM1 11602.1 E 8 4.16E−01 6.2 LYM208 13012.5 P 1.9018.47E−01 4 LYM152 12371.2 E 8 4.16E−01 6.2 LYM183 12994.7 P 1.8578.51E−01 1.6 LYM268 12483.2 E 8 4.16E−01 6.2 LYM198 13005.8 P 1.8428.74E−01 0.8 LYM19 11751.4 E 8.188 4.45E−01 8.6 LYM183 12993.7 P 1.8658.86E−01 2.1 LYM15 11612.3 E 8.25 4.51E−01 9.5 LYM152 12372.2 P 1.8618.88E−01 1.8 LYM268 12482.3 E 8.063 5.16E−01 7 LYM287 12773.7 P 1.868.96E−01 1.8 LYM132 12273.2 E 7.813 5.31E−01 3.7 LYM142 12804.3 P 1.8699.02E−01 2.3 LYM138 12562.1 E 7.75 5.45E−01 2.8 LYM212 13034.9 P 1.879.29E−01 2.3 LYM138 12564.1 E 7.75 5.45E−01 2.8 LYM44 11882.1 P 1.8499.29E−01 1.2 LYM3 12041.1 E 7.75 5.45E−01 2.8 LYM255 13081.5 P 1.8489.43E−01 1.1 LYM148 12173.1 E 8.313 5.58E−01 10.3 LYM137 12152.1 P 1.8349.58E−01 0.3 LYM268 12483.4 E 7.625 5.60E−01 1.2 LYM174 12414.2 P 1.8329.58E−01 0.2 LYM106 12141.4 E 7.688 5.77E−01 2 LYM183 12993.5 P 1.8399.59E−01 0.6 LYM2 11693.3 E 7.688 5.77E−01 2 LYM270 12872.7 P 1.8369.62E−01 0.4 LYM9 11633.2 E 7.688 5.77E−01 2 LYM173 12982.7 P 1.8369.78E−01 0.4 LYM162 12231.1 E 8 5.91E−01 6.2 LYM173 12981.8 P 1.8329.86E−01 0.3 LYM105 12294.2 E 7.875 6.19E−01 4.5 CONTROL — P 1.828 — 0LYM138 12561.3 E 7.875 6.19E−01 4.5 LYM57 12012.2 A 93.32 8.80E−03 2.5LYM174 12412.1 E 7.854 6.25E−01 4.2 LYM14 12054.2 A 93.018 1.70E−02 2.2LYM3 12041.2 E 8.063 6.33E−01 7 LYM148 12171.2 A 93.029 1.75E−02 2.2LYM10 11742.1 E 7.813 6.40E−01 3.7 LYM152 12373.1 A 92.621 4.54E−02 1.8LYM174 12411.3 E 8.125 6.61E−01 7.8 LYM43 11791.2 A 93.704 4.64E−02 2.9LYM129 12573.5 E 7.625 6.64E−01 1.2 LYM140 12262.3 A 92.865 5.07E−02 2LYM102 12221.1 E 7.75 6.70E−01 2.8 LYM132 12273.2 A 93.098 5.40E−02 2.3LYM134 12311.2 E 7.75 6.70E−01 2.8 LYM130 12331.3 A 92.487 5.67E−02 1.6LYM15 11612.2 E 7.75 6.70E−01 2.8 LYM66 11954.5 A 93.427 5.73E−02 2.6LYM3 12043.1 E 7.75 6.70E−01 2.8 LYM119 12461.4 A 93.297 6.70E−02 2.5LYM111 12251.1 E 7.875 6.83E−01 4.5 LYM43 11791.4 A 92.385 7.11E−02 1.5LYM13 11771.6 E 7.875 6.83E−01 4.5 LYM24 12063.3 A 93.233 7.13E−02 2.4LYM9 11632.2 E 7.607 7.08E−01 0.9 LYM290 12504.1 A 93.35 8.10E−02 2.6LYM102 12222.6 E 7.875 7.30E−01 4.5 LYM51 11891.1 A 92.507 8.56E−02 1.6LYM174 12414.2 E 7.75 7.43E−01 2.8 LYM119 12462.1 A 92.346 8.64E−02 1.5LYM100 12131.3 E 7.813 7.57E−01 3.7 LYM14 12051.1 A 93.318 9.94E−02 2.5LYM140 12261.1 E 7.625 7.90E−01 1.2 LYM140 12264.1 A 92.45 1.09E−01 1.6LYM289 12492.2 E 7.643 8.18E−01 1.4 LYM140 12261.4 A 93.706 1.36E−01 2.9LYM10 11744.5 E 7.625 8.54E−01 1.2 LYM100 12131.2 A 92.899 1.46E−01 2.1LYM2 11695.3 E 7.625 8.54E−01 1.2 LYM66 11955.2 A 93.905 1.53E−01 3.2LYM19 11752.2 E 7.688 8.62E−01 2 LYM174 12411.2 A 91.981 1.83E−01 1.1LYM106 12142.2 E 7.563 8.70E−01 0.4 LYM67 11781.5 A 92.297 1.95E−01 1.4LYM143 12523.4 E 7.563 8.70E−01 0.4 LYM57 12012.6 A 92.094 1.96E−01 1.2LYM153 12321.2 E 7.625 8.89E−01 1.2 LYM95 12124.4 A 92.049 2.11E−01 1.1LYM148 12172.1 E 7.563 9.62E−01 0.4 LYM152 12372.2 A 93.098 2.28E−01 2.3LYM148 12174.2 E 7.563 9.62E−01 0.4 LYM172 12302.2 A 91.937 2.30E−01 1LYM4 11705.2 E 7.542 9.88E−01 0.1 LYM119 12462.2 A 92.969 2.34E−01 2.1CONTROL — E 7.536 — 0 LYM95 12124.6 A 93.693 2.49E−01 2.9 LYM143 12524.7F 0.512 4.90E−05 57.7 LYM68 11942.2 A 91.902 2.57E−01 1 LYM138 12561.1 F0.508 5.30E−05 56.2 LYM290 12502.4 A 92.194 3.14E−01 1.3 LYM289 12493.2F 0.485 1.47E−04 49.2 LYM51 11894.2 A 93.154 3.27E−01 2.3 LYM10 11742.2F 0.469 2.28E−04 44.2 LYM53 11844.2 A 92.758 3.35E−01 1.9 LYM102 12222.2F 0.475 3.63E−04 46.1 LYM100 12131.3 A 92.172 3.40E−01 1.3 LYM14812174.1 F 0.455 4.47E−04 40 LYM31 11923.1 A 92.407 3.77E−01 1.5 LYM13212271.4 F 0.454 4.55E−04 39.8 LYM67 11782.6 A 92.138 3.82E−01 1.2 LYM11912463.2 F 0.44 9.36E−04 35.6 LYM3 12043.1 A 91.872 4.24E−01 0.9 LYM1911754.1 F 0.44 9.71E−04 35.6 LYM24 12061.4 A 94.35 4.31E−01 3.7 LYM13212273.2 F 0.455 1.09E−03 40.1 LYM143 12523.4 A 92.469 4.55E−01 1.6 LYM1011741.2 F 0.525 1.40E−03 61.5 LYM14 12051.4 A 92.827 4.66E−01 2 LYM10512293.1 F 0.425 2.11E−03 30.8 LYM170 12453.2 A 91.512 4.71E−01 0.5 LYM1911753.1 F 0.439 2.71E−03 35 LYM138 12566.1 A 91.508 4.74E−01 0.5 LYM411705.2 F 0.42 2.85E−03 29.4 LYM254 12472.3 A 92.469 5.07E−01 1.6 LYM11912461.4 F 0.416 3.48E−03 28.2 LYM254 12474.4 A 93.013 5.16E−01 2.2 LYM1011744.1 F 0.459 7.24E−03 41.1 LYM152 12371.2 A 91.463 5.20E−01 0.5LYM152 12371.2 F 0.399 1.05E−02 22.8 LYM137 12152.1 A 92.231 5.23E−011.3 LYM19 11751.4 F 0.397 1.36E−02 22.1 LYM14 12052.5 A 91.587 5.37E−010.6 LYM130 12334.1 F 0.482 1.68E−02 48.5 LYM69 11852.2 A 92.89 5.41E−012 LYM137 12153.1 F 0.396 1.72E−02 22 LYM68 11942.3 A 91.429 5.48E−01 0.4LYM4 11706.5 F 0.473 1.86E−02 45.6 LYM43 11792.2 A 93.065 5.58E−01 2.2LYM174 12414.3 F 0.515 1.92E−02 58.5 LYM69 11853.5 A 91.52 5.63E−01 0.5LYM289 12491.4 F 0.399 1.98E−02 22.7 LYM69 11853.4 A 91.48 5.87E−01 0.5LYM141 12402.4 F 0.451 2.34E−02 38.9 LYM67 11782.4 A 92.568 6.01E−01 1.7LYM9 11632.1 F 0.557 2.82E−02 71.3 LYM162 12234.3 A 92.261 6.30E−01 1.4LYM140 12262.3 F 0.431 3.06E−02 32.7 LYM132 12275.1 A 91.468 6.30E−010.5 LYM130 12333.1 F 0.439 3.87E−02 35 LYM67 11782.5 A 91.378 6.44E−010.4 LYM152 12372.2 F 0.412 3.93E−02 26.7 LYM268 12481.1 A 91.4416.58E−01 0.5 LYM1 11604.4 F 0.439 4.25E−02 35.1 LYM31 11921.3 A 91.5366.83E−01 0.6 LYM1 11603.2 F 0.377 4.78E−02 16 LYM95 12121.4 A 91.626.87E−01 0.7 LYM141 12404.3 F 0.371 6.69E−02 14.3 LYM143 12524.2 A91.662 7.07E−01 0.7 LYM162 12231.1 F 0.433 7.48E−02 33.4 LYM57 12013.3 A92.476 7.11E−01 1.6 LYM13 11772.1 F 0.369 7.58E−02 13.7 LYM62 12022.4 A91.95 7.18E−01 1 LYM1 11602.1 F 0.379 7.70E−02 16.7 LYM26 11824.1 A91.683 7.41E−01 0.7 LYM162 12231.3 F 0.399 8.40E−02 22.7 LYM174 12412.1A 91.387 7.62E−01 0.4 LYM16 11624.4 F 0.395 8.75E−02 21.6 LYM67 11783.5A 91.709 7.63E−01 0.8 LYM138 12561.3 F 0.468 8.78E−02 44 LYM105 12293.1A 91.757 7.81E−01 0.8 LYM9 11632.2 F 0.385 9.44E−02 18.5 LYM30 11913.5 A91.617 7.83E−01 0.7 LYM140 12261.1 F 0.369 9.78E−02 13.6 LYM95 12124.5 A91.305 7.91E−01 0.3 LYM17 11681.4 F 0.408 9.89E−02 25.5 LYM172 12301.2 A91.351 7.92E−01 0.4 LYM100 12133.1 F 0.432 1.18E−01 33 LYM43 11791.5 A91.202 7.93E−01 0.2 LYM1 11602.6 F 0.554 1.25E−01 70.6 LYM53 11843.2 A94.942 7.95E−01 4.3 LYM174 12411.3 F 0.444 1.29E−01 36.6 LYM170 12454.2A 91.469 7.97E−01 0.5 LYM289 12492.2 F 0.369 1.39E−01 13.6 LYM11912463.2 A 91.489 8.08E−01 0.5 LYM162 12234.4 F 0.427 1.55E−01 31.5LYM111 12254.4 A 91.509 8.21E−01 0.5 LYM140 12264.1 F 0.36 1.58E−01 10.7LYM31 11922.3 A 91.575 8.21E−01 0.6 LYM129 12573.5 F 0.359 1.61E−01 10.5LYM138 12562.1 A 91.448 8.41E−01 0.5 LYM132 12275.1 F 0.399 1.64E−0122.9 LYM174 12411.3 A 91.386 8.43E−01 0.4 LYM153 12323.2 F 0.3581.76E−01 10.2 LYM51 11893.2 A 91.333 8.55E−01 0.3 LYM21 11673.1 F 0.4131.80E−01 27.1 LYM170 12453.3 A 91.321 8.70E−01 0.3 LYM15 11612.2 F 0.3781.96E−01 16.3 LYM62 12021.1 A 91.17 8.74E−01 0.2 LYM162 12234.3 F 0.4241.97E−01 30.6 LYM140 12261.2 A 91.321 8.80E−01 0.3 LYM141 12404.4 F0.418 1.98E−01 28.7 LYM134 12312.4 A 91.24 8.83E−01 0.2 LYM148 12171.2 F0.452 2.19E−01 39 LYM172 12301.3 A 91.364 8.86E−01 0.4 LYM19 11752.2 F0.408 2.21E−01 25.5 LYM152 12372.1 A 91.144 8.89E−01 0.1 LYM119 12462.2F 0.457 2.36E−01 40.7 LYM143 12521.1 A 91.389 8.93E−01 0.4 LYM15 11611.3F 0.446 2.37E−01 37.3 LYM30 11913.3 A 91.204 8.94E−01 0.2 LYM13 11771.6F 0.355 2.37E−01 9.2 LYM119 12461.1 A 91.151 9.05E−01 0.1 LYM19 11751.5F 0.396 2.37E−01 21.9 LYM57 12012.4 A 91.474 9.22E−01 0.5 LYM113 12442.1F 0.407 2.56E−01 25.4 LYM254 12474.3 A 91.298 9.38E−01 0.3 LYM13812564.1 F 0.355 2.62E−01 9.4 LYM14 12052.4 A 91.121 9.52E−01 0.1 LYM1511614.4 F 0.358 2.72E−01 10.1 LYM62 12023.4 A 91.112 9.60E−01 0.1 LYM13012332.2 F 0.481 2.74E−01 48 LYM66 11952.1 A 91.069 9.64E−01 0 LYM111601.1 F 0.403 2.92E−01 24.1 LYM43 11793.2 A 91.06 9.73E−01 0 LYM14012261.4 F 0.359 2.93E−01 10.6 LYM111 12254.3 A 91.041 9.81E−01 0 LYM10212222.3 F 0.451 2.97E−01 38.8 LYM130 12332.2 A 91.095 9.83E−01 0.1 LYM1011742.1 F 0.394 3.00E−01 21.1 LYM152 12376.1 A 91.052 9.90E−01 0 LYM13412311.2 F 0.401 3.03E−01 23.4 CONTROL — A 91.024 — 0 LYM148 12174.2 F0.349 3.05E−01 7.4 LYM69 11853.5 B 0.382 7.33E−03 13.4 LYM174 12414.2 F0.393 3.10E−01 20.9 LYM53 11841.2 B 0.407 1.01E−02 20.8 LYM289 12493.6 F0.38 3.17E−01 17.1 LYM138 12561.1 B 0.418 1.55E−02 24 LYM22 11762.1 F0.361 3.24E−01 11.2 LYM134 12314.2 B 0.366 5.15E−02 8.8 LYM174 12412.1 F0.425 3.25E−01 30.9 LYM140 12264.1 B 0.362 7.22E−02 7.5 LYM21 11671.2 F0.393 3.28E−01 21 LYM119 12461.1 B 0.397 1.11E−01 17.8 LYM111 12251.1 F0.395 3.31E−01 21.4 LYM30 11913.5 B 0.356 1.56E−01 5.6 LYM17 11684.5 F0.347 3.33E−01 6.9 LYM53 11844.2 B 0.377 1.57E−01 11.9 LYM9 11633.7 F0.406 3.55E−01 25 LYM51 11894.2 B 0.358 1.63E−01 6.3 LYM111 12254.4 F0.346 3.64E−01 6.5 LYM51 11891.1 B 0.358 1.64E−01 6.2 LYM143 12524.2 F0.352 3.68E−01 8.3 LYM100 12131.2 B 0.361 1.82E−01 7.3 LYM106 12142.2 F0.351 3.69E−01 8.1 LYM53 11841.1 B 0.361 1.82E−01 7.3 LYM15 11614.3 F0.427 3.69E−01 31.5 LYM111 12251.3 B 0.398 2.06E−01 18.2 LYM10 11744.5 F0.353 3.79E−01 8.6 LYM143 12524.2 B 0.446 2.56E−01 32.3 LYM119 12462.1 F0.49 3.83E−01 50.8 LYM57 12013.5 B 0.383 2.62E−01 13.6 LYM174 12411.2 F0.393 3.90E−01 20.8 LYM138 12561.3 B 0.381 2.70E−01 13.2 LYM268 12483.2F 0.427 3.97E−01 31.4 LYM111 12252.2 B 0.368 2.79E−01 9.1 LYM17 11684.4F 0.379 4.02E−01 16.6 LYM172 12301.2 B 0.35 3.03E−01 3.9 LYM13 11771.9 F0.392 4.05E−01 20.7 LYM138 12562.1 B 0.357 3.98E−01 6 LYM289 12491.1 F0.43 4.12E−01 32.5 LYM268 12482.3 B 0.359 4.07E−01 6.7 LYM290 12502.4 F0.345 4.15E−01 6.3 LYM51 11893.2 B 0.348 4.13E−01 3.4 LYM17 11682.1 F0.41 4.20E−01 26.2 LYM105 12295.2 B 0.367 4.31E−01 8.9 LYM148 12172.1 F0.369 4.31E−01 13.6 LYM105 12293.1 B 0.36 4.56E−01 6.9 LYM105 12294.2 F0.389 4.33E−01 19.8 LYM290 12502.4 B 0.351 4.58E−01 4.3 LYM2 11695.3 F0.351 4.55E−01 7.9 LYM268 12483.2 B 0.373 4.72E−01 10.8 LYM102 12222.6 F0.371 4.65E−01 14.2 LYM143 12521.2 B 0.378 5.08E−01 12.1 LYM15 11612.3 F0.385 4.85E−01 18.5 LYM62 12021.1 B 0.368 5.10E−01 9.3 LYM143 12521.1 F0.353 4.93E−01 8.6 LYM68 11941.4 B 0.408 5.11E−01 21.2 LYM290 12501.3 F0.399 5.13E−01 22.9 LYM290 12501.3 B 0.361 5.13E−01 7.3 LYM153 12321.2 F0.388 5.47E−01 19.4 LYM148 12174.2 B 0.347 5.34E−01 3 LYM17 11683.1 F0.338 5.62E−01 4 LYM31 11923.4 B 0.351 5.39E−01 4.3 LYM268 12483.4 F0.361 5.88E−01 11.1 LYM14 12052.5 B 0.346 5.46E−01 2.8 LYM102 12221.1 F0.348 5.96E−01 7.2 LYM111 12254.4 B 0.346 5.71E−01 2.8 LYM2 11693.3 F0.368 6.14E−01 13.1 LYM51 11893.4 B 0.349 5.77E−01 3.7 LYM138 12562.1 F0.361 6.15E−01 11.1 LYM137 12153.1 B 0.378 5.84E−01 12.3 LYM21 11672.4 F0.347 6.16E−01 6.8 LYM132 12271.4 B 0.346 5.95E−01 2.8 LYM13 11773.2 F0.338 6.25E−01 4 LYM138 12564.1 B 0.346 6.18E−01 2.8 LYM132 12275.3 F0.37 6.32E−01 13.9 LYM30 11913.3 B 0.388 6.38E−01 15.2 LYM130 12331.3 F0.358 6.50E−01 10.2 LYM137 12152.1 B 0.344 6.57E−01 2.3 LYM148 12173.1 F0.378 6.57E−01 16.3 LYM14 12052.4 B 0.346 6.71E−01 2.6 LYM3 12041.2 F0.343 6.88E−01 5.7 LYM119 12462.2 B 0.343 6.92E−01 1.9 LYM137 12151.1 F0.342 6.98E−01 5.3 LYM254 12474.4 B 0.35 6.93E−01 3.9 LYM106 12141.4 F0.349 7.07E−01 7.4 LYM43 11791.5 B 0.341 7.48E−01 1.3 LYM141 12404.2 F0.346 7.13E−01 6.6 LYM62 12022.1 B 0.357 7.54E−01 6 LYM143 12521.2 F0.337 7.26E−01 3.6 LYM53 11842.4 B 0.358 7.57E−01 6.3 LYM105 12294.3 F0.353 7.73E−01 8.6 LYM105 12297.1 B 0.359 7.60E−01 6.7 LYM100 12131.3 F0.345 8.18E−01 6 LYM162 12231.3 B 0.361 7.67E−01 7.3 LYM9 11633.2 F 0.348.64E−01 4.6 LYM137 12151.1 B 0.341 7.73E−01 1.3 LYM111 12252.2 F 0.348.78E−01 4.8 LYM57 12013.3 B 0.362 7.76E−01 7.5 LYM268 12482.1 F 0.338.79E−01 1.6 LYM68 11941.3 B 0.357 7.84E−01 6 LYM113 12444.4 F 0.3289.04E−01 0.8 LYM172 12301.3 B 0.349 8.04E−01 3.7 LYM162 12233.2 F 0.3279.42E−01 0.5 LYM148 12174.1 B 0.347 8.07E−01 3 LYM102 12222.1 F 0.3289.74E−01 0.9 LYM51 11892.1 B 0.344 8.21E−01 2.3 LYM153 12324.1 F 0.3279.76E−01 0.5 LYM53 11843.2 B 0.352 8.35E−01 4.4 LYM106 12144.4 F 0.3269.76E−01 0.3 LYM268 12481.1 B 0.339 8.37E−01 0.8 CONTROL — F 0.325 — 0LYM137 12151.2 B 0.341 8.42E−01 1.3 LYM19 11752.2 G 9.402 2.33E−04 43.1LYM68 11942.3 B 0.343 8.62E−01 1.9 LYM143 12524.7 G 8.849 3.23E−04 34.7LYM290 12502.1 B 0.339 8.75E−01 0.6 LYM132 12275.3 G 8.767 4.00E−04 33.4LYM134 12313.2 B 0.339 8.82E−01 0.6 LYM15 11614.4 G 8.729 4.28E−04 32.9LYM30 11913.4 B 0.355 8.85E−01 5.5 LYM4 11705.2 G 8.616 5.60E−04 31.2LYM152 12373.2 B 0.345 8.86E−01 2.4 LYM9 11632.1 G 8.605 6.15E−04 31LYM31 11922.3 B 0.344 9.08E−01 2.3 LYM13 11772.2 G 8.531 7.47E−04 29.8LYM69 11852.2 B 0.343 9.23E−01 1.9 LYM174 12414.3 G 8.465 9.60E−04 28.8LYM67 11781.5 B 0.34 9.46E−01 1 LYM132 12273.2 G 8.481 1.28E−03 29.1LYM152 12372.1 B 0.339 9.51E−01 0.6 LYM105 12294.3 G 8.32 1.52E−03 26.6LYM57 12012.6 B 0.338 9.53E−01 0.2 LYM138 12561.1 G 8.225 2.11E−03 25.2LYM137 12154.5 B 0.338 9.64E−01 0.4 LYM19 11754.1 G 8.143 2.69E−03 23.9LYM172 12304.2 B 0.341 9.64E−01 1.3 LYM113 12444.5 G 8.015 4.33E−03 22LYM57 12012.2 B 0.338 9.71E−01 0.2 LYM111 12252.2 G 7.972 5.09E−03 21.3LYM268 12482.1 B 0.338 9.86E−01 0.2 LYM153 12324.1 G 8.022 6.24E−03 22.1LYM67 11783.5 B 0.337 9.93E−01 0.1 LYM130 12334.1 G 8.046 6.78E−03 22.5CONTROL — B 0.337 — 0 LYM174 12411.3 G 8.772 1.45E−02 33.5 LYM13712152.1 C 4.388 2.02E−02 15.2 LYM17 11683.1 G 7.679 1.61E−02 16.9 LYM5311844.2 C 4.375 2.89E−02 14.9 LYM130 12331.3 G 7.684 1.97E−02 17 LYM11112251.3 C 4.3 4.04E−02 12.9 LYM15 11611.3 G 7.85 2.01E−02 19.5 LYM5111894.2 C 4.275 4.70E−02 12.3 LYM10 11742.1 G 8.127 2.10E−02 23.7 LYM14812174.2 C 4.325 5.44E−02 13.6 LYM17 11682.1 G 7.604 2.15E−02 15.7 LYM13812561.1 C 4.3 6.41E−02 12.9 LYM111 12254.4 G 7.601 2.17E−02 15.7 LYM11112252.2 C 4.225 6.83E−02 11 LYM153 12321.2 G 8.374 2.39E−02 27.5 LYM11912461.1 C 4.215 8.43E−02 10.7 LYM113 12443.1 G 7.574 2.47E−02 15.3LYM111 12254.4 C 4.181 1.22E−01 9.8 LYM100 12134.1 G 7.562 2.55E−02 15.1LYM53 11841.1 C 4.25 1.46E−01 11.6 LYM289 12493.2 G 8.63 3.01E−02 31.4LYM290 12501.3 C 4.169 1.58E−01 9.5 LYM22 11764.7 G 7.566 3.04E−02 15.2LYM137 12153.1 C 4.641 1.63E−01 21.9 LYM130 12332.1 G 7.505 3.23E−0214.2 LYM143 12524.2 C 4.313 1.76E−01 13.3 LYM1 11601.1 G 9.445 3.25E−0243.8 LYM137 12154.5 C 4.106 1.78E−01 7.9 LYM153 12322.1 G 7.462 3.90E−0213.6 LYM134 12314.2 C 4.344 1.83E−01 14.1 LYM100 12133.1 G 7.9484.23E−02 21 LYM138 12564.1 C 4.194 2.80E−01 10.2 LYM102 12221.1 G 7.4444.24E−02 13.3 LYM254 12474.4 C 4.138 2.93E−01 8.7 LYM140 12261.4 G 7.464.52E−02 13.5 LYM119 12462.2 C 4.131 3.11E−01 8.5 LYM22 11761.3 G 7.4184.69E−02 12.9 LYM51 11893.2 C 4.169 3.79E−01 9.5 LYM105 12293.1 G 7.4045.03E−02 12.7 LYM69 11853.5 C 3.988 3.90E−01 4.7 LYM132 12271.4 G 8.7785.13E−02 33.6 LYM140 12264.1 C 4.113 4.20E−01 8 LYM132 12275.1 G 7.7375.17E−02 17.8 LYM105 12297.1 C 3.981 4.86E−01 4.6 LYM134 12312.3 G 8.6465.27E−02 31.6 LYM51 11893.4 C 4.244 5.14E−01 11.5 LYM162 12234.4 G 7.4615.37E−02 13.6 LYM138 12561.3 C 4.281 5.21E−01 12.4 LYM19 11753.1 G 7.7936.24E−02 18.6 LYM68 11941.4 C 4.123 5.24E−01 8.3 LYM289 12493.6 G 8.2186.32E−02 25.1 LYM134 12312.4 C 3.956 6.33E−01 3.9 LYM138 12566.1 G 7.3498.04E−02 11.9 LYM138 12562.1 C 3.913 6.53E−01 2.8 LYM3 12042.1 G 8.3288.35E−02 26.8 LYM53 11843.2 C 3.975 6.64E−01 4.4 LYM134 12314.2 G 8.4428.52E−02 28.5 LYM53 11841.2 C 4.02 6.89E−01 5.6 LYM21 11674.5 G 7.2619.00E−02 10.5 LYM111 12251.1 C 3.994 7.37E−01 4.9 LYM152 12371.3 G 7.5549.80E−02 15 LYM254 12472.3 C 3.988 7.61E−01 4.7 LYM134 12311.2 G 7.5391.05E−01 14.7 LYM26 11824.1 C 3.969 7.64E−01 4.2 LYM111 12251.1 G 7.5121.05E−01 14.3 LYM172 12304.1 C 3.864 7.87E−01 1.5 LYM106 12144.4 G 7.541.07E−01 14.8 LYM140 12261.1 C 3.856 8.15E−01 1.3 LYM289 12491.4 G 7.4421.10E−01 13.3 LYM51 11891.1 C 3.85 8.33E−01 1.1 LYM13 11773.2 G 7.781.11E−01 18.4 LYM51 11892.1 C 3.856 8.47E−01 1.3 LYM16 11624.4 G 7.5041.12E−01 14.2 LYM137 12151.2 C 3.881 8.63E−01 1.9 LYM162 12233.2 G 7.2051.15E−01 9.7 LYM137 12151.1 C 3.894 8.70E−01 2.3 LYM106 12144.3 G 8.2981.25E−01 26.3 LYM119 12462.1 C 3.831 9.06E−01 0.6 LYM3 12041.2 G 7.3511.34E−01 11.9 LYM26 11824.5 C 3.831 9.06E−01 0.6 LYM138 12562.1 G 7.1561.44E−01 8.9 LYM57 12013.3 C 3.88 9.10E−01 1.9 LYM137 12153.1 G 8.5651.46E−01 30.4 LYM290 12504.1 C 3.856 9.32E−01 1.3 LYM113 12442.2 G 7.7031.48E−01 17.3 LYM254 12474.3 C 3.825 9.39E−01 0.5 LYM17 11681.4 G 7.5061.49E−01 14.3 LYM100 12131.2 C 3.819 9.68E−01 0.3 LYM102 12222.2 G 7.6611.59E−01 16.6 LYM66 11954.5 C 3.813 9.80E−01 0.1 LYM130 12333.1 G 7.5381.65E−01 14.7 LYM57 12012.6 C 3.813 9.80E−01 0.1 LYM113 12442.1 G 8.2771.67E−01 26 CONTROL — C 3.807 — 0 LYM105 12294.2 G 7.504 1.68E−01 14.2LYM134 12314.2 D 0.474 2.43E−04 37.7 LYM10 11742.2 G 8.764 1.69E−01 33.4LYM268 12482.3 D 0.452 7.22E−04 31.3 LYM141 12404.4 G 8.028 1.72E−0122.2 LYM31 11923.4 D 0.442 1.43E−03 28.3 LYM140 12261.1 G 8.77 1.78E−0133.5 LYM138 12561.1 D 0.49 4.94E−03 42.3 LYM1 11602.1 G 7.474 1.80E−0113.8 LYM170 12453.2 D 0.43 7.39E−03 24.9 LYM162 12231.3 G 7.512 1.84E−0114.3 LYM148 12171.2 D 0.435 8.04E−03 26.3 LYM102 12222.3 G 7.9061.85E−01 20.3 LYM57 12013.5 D 0.414 1.08E−02 20.3 LYM100 12131.2 G 7.7831.88E−01 18.5 LYM68 11942.3 D 0.431 1.45E−02 25.2 LYM141 12404.1 G 7.4431.92E−01 13.3 LYM43 11791.5 D 0.471 1.54E−02 36.6 LYM13 11772.1 G 7.6431.99E−01 16.3 LYM140 12264.1 D 0.408 1.74E−02 18.5 LYM1 11602.6 G 7.4431.99E−01 13.3 LYM100 12131.2 D 0.495 4.32E−02 43.5 LYM4 11706.3 G 7.1662.00E−01 9.1 LYM137 12152.1 D 0.39 4.90E−02 13.2 LYM153 12323.2 G 7.9682.11E−01 21.3 LYM57 12012.2 D 0.39 5.17E−02 13.1 LYM2 11695.3 G 7.8192.19E−01 19 LYM69 11853.5 D 0.428 6.11E−02 24.3 LYM3 12043.1 G 8.8562.24E−01 34.8 LYM14 12052.4 D 0.387 6.34E−02 12.5 LYM13 11771.9 G 8.7822.27E−01 33.7 LYM143 12524.2 D 0.459 6.71E−02 33.1 LYM289 12492.2 G7.521 2.28E−01 14.5 LYM53 11841.1 D 0.462 7.65E−02 34.1 LYM162 12231.1 G7.976 2.31E−01 21.4 LYM148 12174.1 D 0.537 8.03E−02 55.9 LYM113 12444.4G 8.066 2.38E−01 22.8 LYM290 12502.4 D 0.444 8.80E−02 28.8 LYM13012332.2 G 8.4 2.46E−01 27.9 LYM105 12294.3 D 0.401 9.08E−02 16.3 LYM1011744.5 G 7.025 2.46E−01 6.9 LYM119 12462.1 D 0.501 1.14E−01 45.4 LYM17412412.1 G 8.37 2.55E−01 27.4 LYM68 11941.3 D 0.429 1.18E−01 24.5 LYM911632.2 G 7.505 2.64E−01 14.2 LYM57 12012.6 D 0.375 1.65E−01 8.9 LYM10012133.3 G 7.444 2.66E−01 13.3 LYM137 12151.1 D 0.427 1.68E−01 23.9LYM152 12372.2 G 7.52 2.67E−01 14.5 LYM30 11913.5 D 0.411 1.70E−01 19.2LYM119 12461.4 G 8.264 2.68E−01 25.8 LYM43 11791.4 D 0.417 1.74E−01 21.1LYM140 12262.3 G 8.232 2.72E−01 25.3 LYM111 12252.2 D 0.658 1.79E−0190.8 LYM140 12264.1 G 8.753 2.84E−01 33.2 LYM138 12561.3 D 0.4522.37E−01 31.3 LYM148 12172.1 G 8.295 2.85E−01 26.3 LYM152 12372.2 D0.381 2.51E−01 10.5 LYM138 12564.1 G 7.27 2.88E−01 10.7 LYM119 12462.2 D0.417 2.52E−01 21.1 LYM143 12521.1 G 7.433 2.89E−01 13.1 LYM111 12254.4D 0.395 2.69E−01 14.7 LYM4 11706.5 G 7.381 2.90E−01 12.4 LYM137 12154.5D 0.408 2.69E−01 18.3 LYM106 12141.4 G 7.836 2.92E−01 19.3 LYM11112251.3 D 0.4 3.04E−01 16 LYM102 12222.6 G 7.608 2.95E−01 15.8 LYM3011912.6 D 0.424 3.16E−01 22.9 LYM2 11693.3 G 7.68 3.07E−01 16.9 LYM6212021.1 D 0.42 3.20E−01 22 LYM106 12142.2 G 8.085 3.09E−01 23.1 LYM26812481.1 D 0.395 3.24E−01 14.6 LYM119 12461.1 G 8.061 3.13E−01 22.7 LYM4311792.2 D 0.386 3.28E−01 12 LYM148 12174.2 G 7.997 3.17E−01 21.7 LYM13012331.3 D 0.364 3.67E−01 5.8 LYM105 12297.1 G 7.589 3.25E−01 15.5 LYM13712153.1 D 0.394 3.68E−01 14.4 LYM10 11744.1 G 8.494 3.37E−01 29.3 LYM6811942.2 D 0.382 3.96E−01 11 LYM290 12501.3 G 8.098 3.38E−01 23.3 LYM6811943.2 D 0.406 4.05E−01 17.7 LYM2 11695.1 G 7.382 3.44E−01 12.4 LYM17212301.2 D 0.412 4.21E−01 19.4 LYM9 11633.7 G 7.296 3.48E−01 11.1 LYM5311844.2 D 0.414 4.32E−01 20.1 LYM174 12414.2 G 7.922 3.51E−01 20.6 LYM5111893.4 D 0.45 4.63E−01 30.7 LYM13 11771.6 G 7.035 3.52E−01 7.1 LYM11912461.1 D 0.486 4.65E−01 41 LYM3 12041.1 G 8.129 3.75E−01 23.7 LYM10512295.2 D 0.379 4.68E−01 10 LYM19 11751.5 G 7.911 3.82E−01 20.4 LYM5111893.2 D 0.368 4.81E−01 6.8 LYM15 11614.3 G 7.807 3.82E−01 18.8 LYM15212376.1 D 0.394 4.85E−01 14.5 LYM1 11604.4 G 7.122 3.96E−01 8.4 LYM13412312.4 D 0.369 4.91E−01 7.2 LYM137 12152.1 G 8.261 4.00E−01 25.7 LYM5111894.2 D 0.36 5.02E−01 4.4 LYM21 11674.1 G 6.882 4.03E−01 4.8 LYM15212372.1 D 0.43 5.13E−01 24.8 LYM137 12151.1 G 7.901 4.07E−01 20.3 LYM6212022.1 D 0.373 5.37E−01 8.1 LYM162 12234.3 G 8.004 4.22E−01 21.8 LYM11112254.3 D 0.446 5.43E−01 29.5 LYM138 12561.3 G 6.87 4.25E−01 4.6 LYM10012131.3 D 0.357 5.49E−01 3.5 LYM289 12491.1 G 7.202 4.30E−01 9.6 LYM14312524.7 D 0.45 5.61E−01 30.6 LYM129 12573.5 G 7.198 4.45E−01 9.6 LYM29012502.2 D 0.401 5.62E−01 16.4 LYM132 12276.1 G 7.232 4.45E−01 10.1 LYM1412051.4 D 0.365 5.63E−01 6 LYM10 11741.2 G 7.633 4.60E−01 16.2 LYM6711783.5 D 0.386 6.06E−01 12 LYM2 11691.2 G 7.396 4.69E−01 12.6 LYM4311793.2 D 0.375 6.13E−01 8.9 LYM17 11684.5 G 7.527 4.73E−01 14.6 LYM3011912.7 D 0.359 6.25E−01 4.1 LYM111 12254.3 G 7.474 4.74E−01 13.8 LYM10012133.3 D 0.356 6.28E−01 3.4 LYM153 12324.2 G 7.351 4.78E−01 11.9 LYM11912461.4 D 0.376 6.48E−01 9.1 LYM17 11684.4 G 7.29 4.79E−01 11 LYM6811941.4 D 0.353 6.66E−01 2.5 LYM119 12462.2 G 6.941 4.86E−01 5.6 LYM10012134.1 D 0.363 6.77E−01 5.5 LYM152 12371.2 G 7.565 4.94E−01 15.2 LYM29012501.3 D 0.362 7.05E−01 5.2 LYM16 11623.5 G 7.011 4.96E−01 6.7 LYM9512124.4 D 0.352 7.39E−01 2.1 LYM141 12404.3 G 7.036 5.07E−01 7.1 LYM2611824.6 D 0.362 7.57E−01 5 LYM21 11673.1 G 8.617 5.09E−01 31.2 LYM14312521.2 D 0.351 7.58E−01 1.8 LYM106 12142.1 G 7.448 5.21E−01 13.4 LYM13812562.1 D 0.363 7.64E−01 5.3 LYM21 11671.2 G 9.058 5.24E−01 37.9 LYM13212275.1 D 0.351 7.77E−01 2 LYM3 12043.2 G 8.688 5.30E−01 32.2 LYM13212276.1 D 0.352 7.92E−01 2.1 LYM141 12402.4 G 7.384 5.30E−01 12.4 LYM25412474.4 D 0.375 7.96E−01 9 LYM113 12441.4 G 7.049 5.31E−01 7.3 LYM13212271.4 D 0.356 8.08E−01 3.4 LYM102 12222.1 G 7.917 5.33E−01 20.5 LYM13012332.2 D 0.357 8.15E−01 3.6 LYM268 12483.2 G 7.794 5.34E−01 18.6 LYM6711782.4 D 0.356 8.23E−01 3.2 LYM22 11762.1 G 7.801 5.39E−01 18.7 LYM5311842.4 D 0.362 8.38E−01 5.2 LYM119 12462.1 G 7.692 5.48E−01 17.1 LYM5111891.1 D 0.348 8.52E−01 1.1 LYM15 11612.3 G 7.175 5.52E−01 9.2 LYM14812173.1 D 0.348 9.01E−01 1 LYM100 12131.3 G 7.145 5.60E−01 8.8 LYM15212373.1 D 0.353 9.14E−01 2.6 LYM143 12523.4 G 7.046 5.67E−01 7.2 LYM16212231.3 D 0.349 9.41E−01 1.3 LYM148 12174.1 G 7.403 5.77E−01 12.7 LYM26812482.1 D 0.35 9.52E−01 1.7 LYM19 11751.4 G 7.084 5.88E−01 7.8 LYM6611954.4 D 0.345 9.97E−01 0.1 LYM143 12521.2 G 6.962 6.60E−01 6 CONTROL —D 0.345 — 0 LYM111 12251.3 G 6.832 6.96E−01 4 LYM111 12252.2 E 9.6887.00E−06 21.3 LYM15 11612.2 G 6.956 6.97E−01 5.9 LYM53 11841.1 E 9.0631.80E−04 13.5 LYM16 11623.2 G 7.05 7.01E−01 7.3 LYM57 12013.5 E 92.83E−04 12.7 LYM105 12297.2 G 6.789 7.14E−01 3.3 LYM105 12297.1 E 8.8756.26E−04 11.2 LYM119 12463.2 G 6.813 7.50E−01 3.7 LYM138 12561.1 E 9.57.87E−04 19 LYM137 12151.2 G 6.992 7.65E−01 6.4 LYM100 12131.2 E 8.8131.02E−03 10.4 LYM268 12483.4 G 6.844 7.81E−01 4.2 LYM148 12174.1 E 9.251.72E−03 15.9 LYM268 12482.1 G 6.755 8.29E−01 2.8 LYM69 11853.5 E 9.251.72E−03 15.9 LYM9 11633.2 G 6.803 8.47E−01 3.5 LYM143 12524.2 E 8.6882.72E−03 8.8 LYM141 12404.2 G 6.786 8.53E−01 3.3 LYM30 11913.5 E 8.6882.72E−03 8.8 LYM290 12502.4 G 6.641 8.59E−01 1.1 LYM30 11913.4 E 8.5984.80E−03 7.7 LYM21 11672.4 G 6.67 8.97E−01 1.5 LYM43 11791.4 E 8.5637.93E−03 7.2 LYM129 12572.2 G 6.616 9.20E−01 0.7 LYM67 11783.5 E 8.7411.00E−02 9.5 LYM134 12312.4 G 6.759 9.21E−01 2.9 LYM140 12264.1 E 8.51.16E−02 6.5 LYM22 11764.1 G 6.648 9.44E−01 1.2 LYM143 12521.2 E 8.51.16E−02 6.5 LYM290 12502.2 G 6.607 9.83E−01 0.6 LYM43 11791.5 E 8.751.31E−02 9.6 LYM148 12173.1 G 6.582 9.90E−01 0.2 LYM68 11941.3 E 8.751.31E−02 9.6 CONTROL — G 6.57 — 0 LYM68 11942.3 E 9.313 1.72E−02 16.6LYM143 12524.7 H 16.067 1.30E−05 63.3 LYM119 12461.1 E 9.188 2.19E−0215.1 LYM148 12171.2 H 16.114 1.80E−05 63.8 LYM143 12524.7 E 9.1882.19E−02 15.1 LYM130 12333.1 H 14.809 6.50E−05 50.5 LYM51 11894.2 E8.438 2.49E−02 5.7 LYM10 11741.2 H 18.71 9.40E−05 90.1 LYM95 12124.4 E8.438 2.49E−02 5.7 LYM4 11706.5 H 14.074 2.31E−04 43 LYM51 11893.2 E9.063 2.84E−02 13.5 LYM102 12222.2 H 14.087 2.46E−04 43.2 LYM30 11913.3E 8.938 3.78E−02 11.9 LYM1 11602.1 H 13.972 2.52E−04 42 LYM14 12052.4 E8.5 5.02E−02 6.5 LYM105 12293.1 H 13.879 3.34E−04 41 LYM290 12502.2 E8.5 5.02E−02 6.5 LYM10 11744.1 H 13.85 3.39E−04 40.8 LYM134 12314.2 E8.813 5.19E−02 10.4 LYM162 12234.3 H 13.567 4.59E−04 37.9 LYM105 12294.2E 8.313 8.12E−02 4.1 LYM140 12262.3 H 12.958 1.39E−03 31.7 LYM13012332.2 E 8.875 1.03E−01 11.2 LYM15 11614.3 H 12.89 1.69E−03 31 LYM13712153.1 E 8.268 1.05E−01 3.6 LYM152 12372.2 H 13.517 5.83E−03 37.4LYM162 12234.3 E 8.375 1.08E−01 4.9 LYM119 12461.4 H 12.416 7.53E−0326.2 LYM290 12501.3 E 8.375 1.08E−01 4.9 LYM1 11602.6 H 19.477 7.70E−0397.9 LYM62 12022.1 E 8.375 1.08E−01 4.9 LYM132 12273.2 H 12.917 1.21E−0231.3 LYM119 12462.2 E 8.563 1.10E−01 7.2 LYM130 12334.1 H 13.0431.44E−02 32.5 LYM172 12302.2 E 8.563 1.10E−01 7.2 LYM100 12133.1 H11.996 1.53E−02 21.9 LYM148 12172.1 E 8.25 1.24E−01 3.3 LYM162 12231.3 H12.208 2.21E−02 24.1 LYM95 12121.2 E 8.25 1.24E−01 3.3 LYM289 12493.2 H14.544 2.84E−02 47.8 LYM130 12331.3 E 8.75 1.31E−01 9.6 LYM119 12463.2 H13.326 3.16E−02 35.4 LYM130 12334.1 E 8.75 1.31E−01 9.6 LYM17 11684.4 H12.364 3.64E−02 25.7 LYM137 12151.1 E 9.25 1.43E−01 15.9 LYM141 12404.2H 11.475 3.87E−02 16.6 LYM68 11941.4 E 8.411 1.43E−01 5.3 LYM1 11603.2 H12.674 4.14E−02 28.8 LYM170 12453.2 E 8.955 1.60E−01 12.2 LYM138 12561.1H 16.127 4.40E−02 63.9 LYM111 12254.3 E 8.625 1.71E−01 8 LYM289 12493.6H 11.22 6.44E−02 14 LYM100 12134.1 E 8.438 1.72E−01 5.7 LYM268 12483.2 H12.016 8.02E−02 22.1 LYM14 12051.4 E 8.438 1.72E−01 5.7 LYM102 12221.1 H11.137 8.39E−02 13.2 LYM68 11942.2 E 8.438 1.72E−01 5.7 LYM19 11751.5 H13.31 8.63E−02 35.3 LYM268 12482.3 E 8.813 1.79E−01 10.4 LYM13 11771.6 H11.597 9.59E−02 17.9 LYM100 12131.3 E 8.5 2.31E−01 6.5 LYM9 11632.2 H11.393 1.03E−01 15.8 LYM100 12133.3 E 8.5 2.31E−01 6.5 LYM9 11632.1 H16.555 1.11E−01 68.2 LYM138 12566.1 E 8.5 2.31E−01 6.5 LYM1 11604.4 H14.531 1.12E−01 47.7 LYM24 12061.2 E 8.5 2.31E−01 6.5 LYM148 12174.1 H14.488 1.13E−01 47.2 LYM26 11824.6 E 8.5 2.31E−01 6.5 LYM141 12402.4 H14.402 1.20E−01 46.4 LYM254 12472.3 E 8.25 2.39E−01 3.3 LYM10 11742.2 H13.928 1.24E−01 41.5 LYM105 12293.1 E 8.188 2.52E−01 2.5 LYM138 12562.1H 10.915 1.30E−01 10.9 LYM51 11891.1 E 8.188 2.52E−01 2.5 LYM19 11753.1H 12.687 1.39E−01 28.9 LYM67 11781.5 E 8.188 2.52E−01 2.5 LYM143 12521.1H 11.254 1.45E−01 14.4 LYM290 12502.1 E 8.75 2.56E−01 9.6 LYM132 12271.4H 12.14 1.46E−01 23.4 LYM148 12173.1 E 9 2.70E−01 12.7 LYM119 12462.2 H17.013 1.48E−01 72.9 LYM111 12251.1 E 8.563 2.76E−01 7.2 LYM174 12411.2H 14.025 1.60E−01 42.5 LYM119 12462.1 E 8.563 2.76E−01 7.2 LYM11312442.1 H 10.841 1.67E−01 10.2 LYM152 12372.1 E 8.563 2.76E−01 7.2 LYM1511612.2 H 11.862 1.76E−01 20.5 LYM51 11893.4 E 8.563 2.76E−01 7.2 LYM411705.2 H 11.33 1.76E−01 15.1 LYM152 12372.2 E 8.313 2.80E−01 4.1 LYM1911754.1 H 11.711 1.84E−01 19 LYM172 12301.2 E 8.313 2.80E−01 4.1 LYM12912573.5 H 10.742 2.00E−01 9.2 LYM268 12483.2 E 8.313 2.80E−01 4.1 LYM911633.7 H 12.318 2.07E−01 25.2 LYM31 11923.1 E 8.313 2.80E−01 4.1 LYM211692.3 H 10.866 2.22E−01 10.4 LYM138 12561.3 E 8.813 2.84E−01 10.4LYM143 12524.2 H 11.856 2.30E−01 20.5 LYM31 11923.4 E 8.813 2.84E−0110.4 LYM130 12332.2 H 13.397 2.34E−01 36.2 LYM290 12504.1 E 8.832.91E−01 10.6 LYM119 12462.1 H 14.498 2.51E−01 47.3 LYM62 12021.1 E8.625 3.08E−01 8 LYM21 11673.1 H 11.772 2.65E−01 19.6 LYM132 12271.4 E8.375 3.23E−01 4.9 LYM174 12414.3 H 14.966 2.87E−01 52.1 LYM137 12154.5E 8.688 3.33E−01 8.8 LYM138 12561.3 H 14.529 2.90E−01 47.7 LYM68 11943.2E 8.688 3.33E−01 8.8 LYM141 12404.3 H 12.256 2.98E−01 24.6 LYM15212376.1 E 8.438 3.55E−01 5.7 LYM15 11612.3 H 13.103 2.99E−01 33.2 LYM29012502.4 E 8.438 3.55E−01 5.7 LYM134 12311.2 H 12.68 3.01E−01 28.9 LYM3111922.3 E 8.438 3.55E−01 5.7 LYM15 11611.3 H 12.542 3.17E−01 27.5 LYM5311844.2 E 8.438 3.55E−01 5.7 LYM19 11751.4 H 13.251 3.21E−01 34.7 LYM11112254.4 E 9.188 3.72E−01 15.1 LYM162 12231.1 H 12.669 3.42E−01 28.8LYM153 12321.2 E 8.491 3.76E−01 6.3 LYM289 12491.4 H 11.387 3.46E−0115.7 LYM152 12371.2 E 8.563 3.96E−01 7.2 LYM17 11684.5 H 10.515 3.52E−016.9 LYM105 12295.2 E 8.625 4.09E−01 8 LYM152 12371.2 H 12.307 3.54E−0125.1 LYM30 11912.6 E 8.313 4.71E−01 4.1 LYM21 11671.2 H 12.04 3.73E−0122.4 LYM51 11892.1 E 8.313 4.71E−01 4.1 LYM290 12501.3 H 11.464 3.76E−0116.5 LYM57 12012.2 E 8.313 4.71E−01 4.1 LYM16 11624.4 H 10.469 3.83E−016.4 LYM138 12562.1 E 8.188 4.71E−01 2.5 LYM141 12404.4 H 12.483 3.95E−0126.9 LYM140 12261.4 E 8.188 4.71E−01 2.5 LYM289 12491.1 H 13.3583.97E−01 35.8 LYM162 12231.1 E 8.188 4.71E−01 2.5 LYM17 11683.1 H 10.4484.15E−01 6.2 LYM140 12262.3 E 8.375 4.75E−01 4.9 LYM148 12173.1 H 12.8424.17E−01 30.5 LYM148 12171.2 E 8.5 4.82E−01 6.5 LYM162 12234.4 H 14.1454.21E−01 43.7 LYM30 11912.7 E 8.563 4.85E−01 7.2 LYM13 11772.1 H 10.8154.47E−01 9.9 LYM268 12481.1 E 8.625 4.87E−01 8 LYM174 12411.3 H 11.9254.47E−01 21.2 LYM100 12133.1 E 8.125 5.09E−01 1.8 LYM268 12483.4 H11.476 4.61E−01 16.6 LYM137 12152.1 E 8.125 5.09E−01 1.8 LYM174 12412.1H 11.503 4.65E−01 16.9 LYM14 12052.5 E 8.125 5.09E−01 1.8 LYM102 12222.3H 12.838 4.66E−01 30.5 LYM26 11824.5 E 8.125 5.09E−01 1.8 LYM111 12251.1H 11.987 4.83E−01 21.8 LYM132 12275.1 E 8.563 5.52E−01 7.2 LYM21 11672.4H 11.725 4.84E−01 19.2 LYM53 11842.4 E 8.5 5.58E−01 6.5 LYM268 12482.3 H10.787 4.91E−01 9.6 LYM57 12012.6 E 8.25 6.05E−01 3.3 LYM174 12414.2 H10.274 5.09E−01 4.4 LYM69 11853.4 E 8.5 6.15E−01 6.5 LYM10 11744.5 H11.527 5.13E−01 17.1 LYM132 12276.1 E 8.241 6.23E−01 3.2 LYM290 12502.4H 11.749 5.22E−01 19.4 LYM105 12294.3 E 8.188 6.34E−01 2.5 LYM17 11682.1H 12.286 5.68E−01 24.9 LYM69 11852.4 E 8.188 6.34E−01 2.5 LYM105 12294.2H 12.291 6.34E−01 24.9 LYM95 12124.5 E 8.063 6.47E−01 1 LYM137 12153.1 H10.938 6.48E−01 11.2 LYM95 12124.6 E 8.125 6.82E−01 1.8 LYM17 11681.4 H10.405 6.58E−01 5.7 LYM43 11793.2 E 8.438 7.13E−01 5.7 LYM10 11742.1 H11.348 7.13E−01 15.3 LYM130 12332.1 E 8.375 7.33E−01 4.9 LYM111 12252.2H 11.494 7.14E−01 16.8 LYM140 12261.1 E 8.25 7.45E−01 3.3 LYM100 12131.3H 10.807 7.19E−01 9.8 LYM67 11782.6 E 8.063 7.71E−01 1 LYM140 12261.4 H10.294 7.56E−01 4.6 LYM14 12051.1 E 8.125 7.75E−01 1.8 LYM9 11633.2 H10.562 7.61E−01 7.3 LYM254 12474.4 E 8.188 7.80E−01 2.5 LYM162 12233.2 H10.524 7.66E−01 6.9 LYM268 12482.1 E 8.259 8.09E−01 3.4 LYM132 12275.1 H10.029 7.80E−01 1.9 LYM69 11854.2 E 8.107 8.10E−01 1.5 LYM148 12172.1 H10.795 8.12E−01 9.7 LYM130 12333.1 E 8.063 8.49E−01 1 LYM268 12482.1 H10.48 8.16E−01 6.5 LYM138 12564.1 E 8.063 8.49E−01 1 LYM290 12502.1 H10.411 8.38E−01 5.8 LYM170 12452.3 E 8.063 8.49E−01 1 LYM22 11762.1 H10.161 8.39E−01 3.3 LYM134 12311.2 E 8.125 8.60E−01 1.8 LYM1 11601.1 H10.24 8.44E−01 4.1 LYM62 12022.2 E 8.125 8.60E−01 1.8 LYM2 11693.3 H10.026 8.49E−01 1.9 LYM66 11954.4 E 8.125 8.82E−01 1.8 LYM143 12521.2 H9.995 9.08E−01 1.6 LYM3 12043.1 E 8.063 9.13E−01 1 LYM13 11771.9 H 9.9189.11E−01 0.8 LYM152 12373.1 E 8 9.40E−01 0.2 LYM290 12504.1 H 10.0349.18E−01 2 LYM153 12322.1 E 8 9.63E−01 0.2 LYM143 12523.4 H 10.0419.29E−01 2 LYM31 11924.4 E 8 9.80E−01 0.2 LYM102 12222.6 H 10.0689.54E−01 2.3 CONTROL — E 7.984 — 0 LYM111 12254.4 H 9.865 9.76E−01 0.3LYM137 12151.1 F 0.636 3.25E−04 50 CONTROL — H 9.84 — 0 LYM57 12013.5 F0.605 7.25E−04 42.7 LYM1 11602.6 J 0.05 2.90E−05 82.4 LYM134 12314.2 F0.605 7.28E−04 42.7 LYM10 11741.2 J 0.047 2.61E−04 69.6 LYM138 12561.3 F0.603 8.37E−04 42.2 LYM148 12171.2 J 0.044 1.16E−03 57.9 LYM51 11893.2 F0.607 1.97E−03 43 LYM143 12524.7 J 0.043 1.72E−03 56 LYM268 12482.3 F0.576 2.18E−03 35.7 LYM119 12462.2 J 0.044 2.18E−03 60.3 LYM68 11942.3 F0.57 2.74E−03 34.3 LYM9 11632.1 J 0.042 3.46E−03 51.9 LYM148 12174.1 F0.795 3.37E−03 87.5 LYM138 12561.1 J 0.039 1.28E−02 42.5 LYM290 12502.4F 0.563 3.59E−03 32.8 LYM1 11604.4 J 0.039 1.45E−02 41.6 LYM69 11853.5 F0.63 4.12E−03 48.5 LYM1 11602.1 J 0.039 1.68E−02 41.3 LYM68 11941.3 F0.676 4.18E−03 59.3 LYM138 12561.3 J 0.038 2.14E−02 39.2 LYM137 12153.1F 0.544 7.80E−03 28.2 LYM289 12493.2 J 0.038 3.13E−02 38 LYM137 12154.5F 0.584 1.03E−02 37.8 LYM10 11742.2 J 0.038 3.37E−02 35.8 LYM143 12521.2F 0.541 1.35E−02 27.5 LYM174 12414.3 J 0.038 3.60E−02 37.6 LYM43 11791.5F 0.552 1.40E−02 30.2 LYM162 12234.4 J 0.039 3.75E−02 39.7 LYM30 11913.4F 0.578 1.86E−02 36.3 LYM130 12333.1 J 0.037 4.04E−02 34.6 LYM30 11913.5F 0.537 1.99E−02 26.7 LYM102 12222.2 J 0.037 4.21E−02 33.3 LYM29012501.3 F 0.516 2.54E−02 21.7 LYM174 12411.2 J 0.037 4.72E−02 33.9 LYM5311841.1 F 0.632 2.58E−02 49.1 LYM162 12234.3 J 0.037 4.72E−02 34 LYM17012453.2 F 0.511 3.14E−02 20.5 LYM15 11614.3 J 0.037 4.86E−02 32.3 LYM14012264.1 F 0.508 3.58E−02 19.9 LYM148 12174.1 J 0.036 5.71E−02 30.8 LYM3011913.3 F 0.513 4.45E−02 20.9 LYM105 12293.1 J 0.036 5.84E−02 31.5LYM105 12297.1 F 0.503 4.63E−02 18.6 LYM140 12262.3 J 0.036 6.17E−02 30LYM62 12022.1 F 0.501 5.09E−02 18.2 LYM119 12462.1 J 0.036 6.65E−02 30.3LYM31 11923.4 F 0.574 5.51E−02 35.4 LYM10 11744.1 J 0.036 7.19E−02 29.9LYM68 11943.2 F 0.604 5.83E−02 42.4 LYM19 11751.5 J 0.036 7.62E−02 29.3LYM152 12372.2 F 0.517 5.83E−02 21.9 LYM141 12402.4 J 0.036 7.71E−0230.2 LYM105 12295.2 F 0.552 6.04E−02 30.1 LYM152 12372.2 J 0.0359.41E−02 27.8 LYM137 12152.1 F 0.504 6.15E−02 18.8 LYM134 12311.2 J0.036 9.65E−02 28.5 LYM138 12561.1 F 0.644 7.28E−02 51.8 LYM19 11751.4 J0.036 9.82E−02 28.8 LYM62 12021.1 F 0.504 8.04E−02 18.8 LYM15 11611.3 J0.036 1.02E−01 30.1 LYM30 11912.6 F 0.521 9.04E−02 22.9 LYM162 12231.3 J0.035 1.13E−01 25.7 LYM111 12252.2 F 0.817 9.40E−02 92.5 LYM15 11612.3 J0.035 1.21E−01 26.5 LYM119 12462.2 F 0.513 9.81E−02 21 LYM148 12173.1 J0.035 1.32E−01 26.4 LYM290 12502.2 F 0.524 1.07E−01 23.6 LYM1 11603.2 J0.034 1.32E−01 24.2 LYM100 12131.2 F 0.575 1.17E−01 35.6 LYM17 11684.4 J0.034 1.34E−01 24 LYM14 12051.1 F 0.488 1.25E−01 15.1 LYM174 12412.1 J0.035 1.37E−01 26.8 LYM290 12502.1 F 0.48 1.39E−01 13.1 LYM162 12231.1 J0.034 1.41E−01 24.4 LYM143 12524.2 F 0.594 1.41E−01 40 LYM132 12273.2 J0.034 1.52E−01 22.6 LYM138 12562.1 F 0.512 1.65E−01 20.7 LYM132 12271.4J 0.034 1.55E−01 23.2 LYM138 12564.1 F 0.472 1.84E−01 11.3 LYM4 11705.2J 0.034 1.60E−01 23.1 LYM172 12301.2 F 0.511 1.88E−01 20.4 LYM19 11753.1J 0.034 1.68E−01 21.9 LYM152 12376.1 F 0.528 1.96E−01 24.5 LYM11912461.4 J 0.034 1.68E−01 22.2 LYM14 12052.4 F 0.532 1.98E−01 25.5 LYM28912491.1 J 0.034 1.81E−01 21.7 LYM119 12462.1 F 0.567 2.22E−01 33.7LYM119 12463.2 J 0.034 1.84E−01 21.5 LYM100 12134.1 F 0.508 2.22E−0119.7 LYM141 12404.3 J 0.033 2.00E−01 21 LYM105 12294.3 F 0.516 2.28E−0121.6 LYM130 12332.2 J 0.034 2.03E−01 21.2 LYM132 12271.4 F 0.5 2.30E−0117.9 LYM141 12404.4 J 0.033 2.07E−01 20.4 LYM51 11891.1 F 0.471 2.32E−0111 LYM4 11706.5 J 0.033 2.13E−01 19.8 LYM67 11783.5 F 0.541 2.36E−0127.6 LYM9 11633.7 J 0.033 2.16E−01 21 LYM26 11824.6 F 0.516 2.42E−0121.6 LYM152 12371.2 J 0.033 2.34E−01 19.7 LYM268 12481.1 F 0.5222.44E−01 23 LYM17 11682.1 J 0.033 2.45E−01 20.4 LYM14 12051.4 F 0.4672.48E−01 10.2 LYM21 11673.1 J 0.033 2.57E−01 18.1 LYM148 12171.2 F 0.4682.60E−01 10.4 LYM21 11672.4 J 0.033 2.70E−01 18.7 LYM130 12332.2 F 0.4662.86E−01 9.9 LYM15 11612.2 J 0.032 2.77E−01 17.4 LYM100 12133.3 F 0.4742.88E−01 11.8 LYM9 11632.2 J 0.032 2.83E−01 17.2 LYM53 11844.2 F 0.5223.01E−01 23.1 LYM143 12521.1 J 0.032 2.83E−01 17.1 LYM51 11893.4 F 0.6153.06E−01 45.1 LYM143 12524.2 J 0.032 2.84E−01 17.3 LYM152 12372.1 F0.625 3.14E−01 47.3 LYM102 12222.3 J 0.033 2.90E−01 18.6 LYM111 12251.1F 0.468 3.26E−01 10.4 LYM10 11744.5 J 0.032 3.16E−01 16.9 LYM162 12231.3F 0.47 3.29E−01 10.8 LYM13 11771.6 J 0.032 3.27E−01 16.2 LYM119 12461.1F 0.649 3.29E−01 52.9 LYM111 12251.1 J 0.032 3.47E−01 16.1 LYM14312524.7 F 0.583 3.35E−01 37.3 LYM105 12294.2 J 0.032 3.57E−01 17.1LYM130 12331.3 F 0.48 3.48E−01 13.2 LYM174 12411.3 J 0.032 3.66E−01 14.4LYM130 12334.1 F 0.476 3.58E−01 12.3 LYM19 11754.1 J 0.032 3.67E−01 14.1LYM132 12275.1 F 0.456 3.63E−01 7.5 LYM268 12483.2 J 0.031 3.73E−01 13.8LYM111 12254.4 F 0.553 3.74E−01 30.4 LYM268 12483.4 J 0.032 3.80E−01 15LYM111 12254.3 F 0.603 3.81E−01 42.1 LYM290 12502.4 J 0.032 3.97E−0114.2 LYM148 12173.1 F 0.513 4.04E−01 20.9 LYM289 12493.6 J 0.0314.46E−01 11.8 LYM68 11942.2 F 0.489 4.14E−01 15.3 LYM141 12404.2 J 0.0314.48E−01 12.2 LYM57 12012.2 F 0.462 4.14E−01 9 LYM13 11772.1 J 0.0314.52E−01 12.1 LYM57 12012.6 F 0.462 4.28E−01 9 LYM21 11671.2 J 0.0314.72E−01 11.1 LYM100 12131.3 F 0.482 4.31E−01 13.6 LYM129 12573.5 J0.031 4.89E−01 10.8 LYM153 12321.2 F 0.507 4.37E−01 19.5 LYM17 11681.4 J0.031 4.90E−01 10.8 LYM162 12234.3 F 0.456 4.41E−01 7.6 LYM143 12521.2 J0.03 5.23E−01 10.1 LYM24 12061.2 F 0.515 4.44E−01 21.5 LYM148 12172.1 J0.031 5.23E−01 11.5 LYM134 12312.4 F 0.467 4.57E−01 10.2 LYM289 12491.4J 0.03 5.61E−01 9.4 LYM68 11941.4 F 0.465 4.72E−01 9.6 LYM100 12133.1 J0.03 5.63E−01 9 LYM30 11912.7 F 0.485 4.92E−01 14.2 LYM102 12221.1 J0.03 5.66E−01 9.1 LYM132 12276.1 F 0.513 4.98E−01 21 LYM100 12131.3 J0.03 5.87E−01 9.1 LYM95 12124.4 F 0.454 5.03E−01 7.1 LYM2 11692.3 J 0.035.92E−01 8.4 LYM148 12174.2 F 0.467 5.95E−01 10.2 LYM16 11624.4 J 0.036.06E−01 8 LYM43 11791.4 F 0.488 5.95E−01 15.1 LYM290 12501.3 J 0.036.10E−01 8.3 LYM152 12371.2 F 0.476 6.25E−01 12.3 LYM10 11742.1 J 0.036.16E−01 8.9 LYM66 11954.4 F 0.501 6.29E−01 18.2 LYM138 12562.1 J 0.036.36E−01 7.3 LYM67 11781.5 F 0.446 6.32E−01 5.3 LYM17 11684.5 J 0.036.40E−01 7.2 LYM67 11782.6 F 0.442 6.43E−01 4.3 LYM111 12252.2 J 0.036.46E−01 8.2 LYM140 12261.1 F 0.465 6.49E−01 9.6 LYM268 12482.1 J 0.036.52E−01 7.8 LYM172 12302.2 F 0.471 6.57E−01 11 LYM17 11683.1 J 0.0296.68E−01 6.6 LYM31 11922.3 F 0.47 6.61E−01 10.8 LYM1 11601.1 J 0.0296.76E−01 6.7 LYM14 12052.5 F 0.439 6.69E−01 3.4 LYM137 12153.1 J 0.0296.95E−01 6.6 LYM51 11894.2 F 0.44 6.79E−01 3.7 LYM162 12233.2 J 0.0296.97E−01 6.4 LYM170 12452.3 F 0.441 6.91E−01 3.9 LYM268 12482.3 J 0.0297.03E−01 6 LYM153 12322.1 F 0.485 6.92E−01 14.4 LYM130 12334.1 J 0.0297.32E−01 5.2 LYM62 12022.2 F 0.464 7.01E−01 9.4 LYM22 11762.1 J 0.0298.38E−01 3.2 LYM105 12293.1 F 0.448 7.04E−01 5.7 LYM140 12261.4 J 0.0288.73E−01 2.6 LYM31 11923.1 F 0.451 7.09E−01 6.4 LYM143 12523.4 J 0.0289.21E−01 1.6 LYM69 11854.2 F 0.447 7.13E−01 5.5 LYM111 12254.4 J 0.0289.41E−01 1.1 LYM268 12482.1 F 0.486 7.27E−01 14.5 LYM2 11693.3 J 0.0289.79E−01 0.4 LYM119 12461.4 F 0.444 7.34E−01 4.8 LYM102 12222.6 J 0.0289.79E−01 0.5 LYM268 12483.2 F 0.461 7.41E−01 8.6 LYM113 12442.1 J 0.0289.82E−01 0.4 LYM111 12251.3 F 0.452 7.42E−01 6.5 CONTROL — J 0.028 — 0LYM162 12231.1 F 0.45 7.55E−01 6.2 LYM119 12462.2 K 0.627 1.12E−02 31.8LYM100 12133.1 F 0.446 7.57E−01 5.3 LYM148 12174.1 K 0.617 2.05E−02 29.8LYM26 11824.5 F 0.442 7.76E−01 4.1 LYM268 12483.2 K 0.607 2.07E−02 27.7LYM152 12373.1 F 0.46 7.98E−01 8.4 LYM268 12482.3 K 0.612 2.74E−02 28.6LYM69 11853.4 F 0.455 8.07E−01 7.3 LYM102 12222.6 K 0.616 3.04E−02 29.6LYM254 12474.4 F 0.466 8.11E−01 9.9 LYM4 11706.5 K 0.603 3.66E−02 26.7LYM172 12301.3 F 0.439 8.30E−01 3.6 LYM102 12222.2 K 0.608 4.08E−02 27.9LYM95 12124.5 F 0.43 8.69E−01 1.4 LYM143 12524.7 K 0.614 4.15E−02 29.2LYM130 12333.1 F 0.438 8.73E−01 3.2 LYM15 11611.3 K 0.59 4.46E−02 24.1LYM148 12172.1 F 0.431 8.75E−01 1.7 LYM140 12261.1 K 0.585 4.64E−02 22.9LYM53 11842.4 F 0.449 8.83E−01 5.8 LYM119 12461.4 K 0.589 4.73E−02 23.8LYM43 11793.2 F 0.446 9.06E−01 5.1 LYM21 11674.5 K 0.581 5.23E−02 22.2LYM140 12262.3 F 0.433 9.11E−01 2.2 LYM132 12271.4 K 0.584 5.49E−02 22.8LYM254 12472.3 F 0.429 9.16E−01 1.1 LYM130 12332.2 K 0.586 6.37E−02 23.3LYM137 12151.2 F 0.436 9.21E−01 2.7 LYM100 12131.2 K 0.584 7.48E−02 22.8CONTROL — F 0.424 — 0 LYM100 12133.1 K 0.583 8.16E−02 22.7 LYM14812174.1 G 10.531 6.00E−05 46.2 LYM138 12561.1 K 0.582 9.29E−02 22.5LYM105 12297.1 G 9.406 9.40E−05 30.6 LYM141 12402.4 K 0.578 9.33E−0221.5 LYM137 12154.5 G 9.272 1.82E−04 28.7 LYM10 11741.2 K 0.572 9.81E−0220.4 LYM290 12502.1 G 9.121 2.85E−04 26.6 LYM10 11742.2 K 0.571 1.03E−0120 LYM132 12271.4 G 8.899 5.40E−04 23.5 LYM152 12372.2 K 0.572 1.06E−0120.2 LYM111 12252.2 G 8.923 5.44E−04 23.9 LYM105 12293.1 K 0.5641.39E−01 18.6 LYM290 12502.2 G 8.832 7.44E−04 22.6 LYM17 11681.4 K 0.5661.40E−01 19.1 LYM143 12524.2 G 8.77 9.08E−04 21.7 LYM137 12153.1 K 0.5641.47E−01 18.5 LYM268 12482.3 G 8.973 1.05E−03 24.6 LYM21 11671.2 K 0.5691.48E−01 19.6 LYM67 11781.5 G 8.534 2.64E−03 18.5 LYM10 11742.1 K 0.5641.50E−01 18.6 LYM138 12561.1 G 10.311 3.08E−03 43.1 LYM289 12491.4 K0.549 1.64E−01 15.5 LYM138 12561.3 G 9.901 3.55E−03 37.4 LYM153 12321.2K 0.553 1.68E−01 16.3 LYM57 12013.5 G 9.583 3.82E−03 33 LYM289 12491.1 K0.573 1.78E−01 20.5 LYM143 12524.7 G 8.422 3.87E−03 16.9 LYM174 12411.2K 0.56 1.82E−01 17.7 LYM290 12501.3 G 8.474 4.45E−03 17.6 LYM22 11764.1K 0.547 1.85E−01 15 LYM153 12322.1 G 8.566 4.91E−03 18.9 LYM289 12493.2K 0.549 1.87E−01 15.5 LYM67 11783.5 G 8.896 8.15E−03 23.5 LYM106 12142.2K 0.547 1.97E−01 15 LYM140 12261.1 G 8.624 9.34E−03 19.7 LYM174 12412.1K 0.557 2.01E−01 17.2 LYM43 11791.5 G 8.227 1.13E−02 14.2 LYM174 12414.2K 0.549 2.07E−01 15.5 LYM268 12483.2 G 8.173 1.25E−02 13.4 LYM10512297.1 K 0.55 2.08E−01 15.6 LYM111 12251.1 G 8.206 1.25E−02 13.9 LYM15212373.1 K 0.542 2.24E−01 14 LYM100 12134.1 G 8.493 1.46E−02 17.9 LYM2211764.7 K 0.545 2.25E−01 14.5 LYM30 11913.5 G 9.106 1.46E−02 26.4 LYM11912462.1 K 0.555 2.28E−01 16.8 LYM134 12311.2 G 8.005 2.81E−02 11.1 LYM111602.6 K 0.561 2.30E−01 18 LYM130 12334.1 G 8.539 3.38E−02 18.5 LYM13012334.1 K 0.559 2.36E−01 17.5 LYM162 12231.1 G 9.308 3.90E−02 29.2LYM138 12564.1 K 0.546 2.43E−01 14.8 LYM30 11912.7 G 7.962 4.08E−02 10.5LYM268 12481.1 K 0.536 2.59E−01 12.6 LYM68 11941.3 G 10.235 4.13E−0242.1 LYM3 12041.2 K 0.551 2.68E−01 15.9 LYM100 12133.1 G 8.264 5.83E−0214.7 LYM102 12222.3 K 0.546 2.81E−01 14.8 LYM153 12324.1 G 9.0595.91E−02 25.7 LYM162 12234.3 K 0.541 2.97E−01 13.9 LYM100 12131.3 G7.845 6.29E−02 8.9 LYM162 12234.4 K 0.54 3.06E−01 13.6 LYM268 12483.4 G8.176 6.43E−02 13.5 LYM148 12173.1 K 0.547 3.18E−01 15.1 LYM31 11923.4 G8.75 7.07E−02 21.5 LYM290 12501.3 K 0.533 3.19E−01 12 LYM57 12012.2 G8.174 8.06E−02 13.5 LYM9 11632.1 K 0.537 3.25E−01 13 LYM174 12411.3 G9.046 8.44E−02 25.6 LYM113 12442.1 K 0.527 3.29E−01 10.9 LYM53 11843.2 G7.796 8.61E−02 8.2 LYM19 11754.1 K 0.527 3.47E−01 10.8 LYM137 12151.1 G10.024 8.70E−02 39.1 LYM111 12251.1 K 0.532 3.60E−01 11.9 LYM111 12254.3G 8.786 9.05E−02 22 LYM119 12463.2 K 0.533 3.81E−01 12.1 LYM95 12121.2 G7.752 1.05E−01 7.6 LYM15 11614.3 K 0.525 3.92E−01 10.4 LYM162 12234.4 G8.337 1.12E−01 15.7 LYM140 12264.1 K 0.524 3.93E−01 10.2 LYM30 11913.3 G8.024 1.18E−01 11.4 LYM19 11753.1 K 0.523 4.08E−01 10 LYM105 12295.2 G8.798 1.36E−01 22.1 LYM141 12404.3 K 0.525 4.11E−01 10.3 LYM3 12042.1 G7.697 1.37E−01 6.8 LYM10 11744.1 K 0.522 4.16E−01 9.8 LYM132 12275.1 G7.686 1.44E−01 6.7 LYM130 12331.3 K 0.523 4.27E−01 9.9 LYM68 11942.2 G8.305 1.48E−01 15.3 LYM289 12493.6 K 0.519 4.34E−01 9.2 LYM137 12152.1 G8.278 1.51E−01 14.9 LYM19 11752.2 K 0.532 4.41E−01 11.8 LYM152 12372.1 G9.361 1.57E−01 29.9 LYM138 12562.1 K 0.519 4.60E−01 9.2 LYM268 12482.1 G9.011 1.64E−01 25.1 LYM290 12502.4 K 0.519 4.61E−01 9.1 LYM134 12314.2 G9.935 1.83E−01 37.9 LYM105 12294.3 K 0.518 5.00E−01 8.9 LYM162 12231.3 G8.428 1.87E−01 17 LYM1 11603.2 K 0.515 5.19E−01 8.3 LYM66 11952.1 G8.194 1.92E−01 13.7 LYM174 12414.3 K 0.513 5.33E−01 7.8 LYM66 11954.4 G8.631 2.06E−01 19.8 LYM17 11682.1 K 0.515 5.34E−01 8.2 LYM43 11791.4 G8.574 2.13E−01 19 LYM290 12502.2 K 0.521 5.41E−01 9.6 LYM26 11824.6 G8.67 2.15E−01 20.3 LYM141 12404.4 K 0.514 5.48E−01 8.1 LYM31 11921.3 G8.127 2.23E−01 12.8 LYM3 12041.1 K 0.508 5.57E−01 6.9 LYM148 12174.2 G9.026 2.26E−01 25.3 LYM268 12482.1 K 0.506 5.59E−01 6.5 LYM111 12251.3 G8.396 2.31E−01 16.5 LYM162 12233.2 K 0.506 5.75E−01 6.4 LYM24 12062.3 G8.378 2.38E−01 16.3 LYM152 12371.3 K 0.507 5.75E−01 6.6 LYM137 12151.2 G7.637 2.41E−01 6 LYM162 12231.1 K 0.513 5.85E−01 7.8 LYM111 12254.4 G8.571 2.44E−01 19 LYM152 12371.2 K 0.505 5.88E−01 6.2 LYM68 11942.3 G7.989 2.45E−01 10.9 LYM106 12141.4 K 0.505 5.96E−01 6.1 LYM153 12323.2 G7.588 2.51E−01 5.3 LYM15 11612.3 K 0.506 6.17E−01 6.4 LYM138 12564.1 G8.799 2.53E−01 22.1 LYM105 12297.2 K 0.507 6.20E−01 6.5 LYM67 11782.6 G7.563 2.57E−01 5 LYM105 12294.2 K 0.505 6.39E−01 6.1 LYM68 11943.2 G8.649 2.60E−01 20.1 LYM21 11672.4 K 0.504 6.50E−01 5.9 LYM62 12022.1 G8.781 2.63E−01 21.9 LYM1 11604.4 K 0.5 6.53E−01 5.1 LYM14 12051.1 G7.587 2.72E−01 5.3 LYM15 11612.2 K 0.502 6.56E−01 5.6 LYM138 12562.1 G8.862 2.79E−01 23 LYM141 12404.2 K 0.501 6.61E−01 5.3 LYM152 12376.1 G7.952 2.80E−01 10.4 LYM17 11684.4 K 0.502 6.69E−01 5.5 LYM26 11821.2 G7.544 2.80E−01 4.7 LYM19 11751.4 K 0.504 6.71E−01 5.9 LYM105 12294.3 G8.885 2.83E−01 23.3 LYM10 11744.5 K 0.498 6.80E−01 4.8 LYM26 11824.5 G7.682 2.83E−01 6.6 LYM4 11706.3 K 0.496 6.93E−01 4.4 LYM100 12131.2 G7.596 2.88E−01 5.4 LYM132 12275.1 K 0.498 7.10E−01 4.8 LYM137 12153.1 G9.256 2.90E−01 28.5 LYM113 12444.4 K 0.494 7.42E−01 3.8 LYM51 11891.1 G7.81 2.91E−01 8.4 LYM129 12573.5 K 0.494 7.44E−01 3.8 LYM69 11853.5 G8.643 2.92E−01 20 LYM13 11773.2 K 0.492 7.46E−01 3.5 LYM51 11893.4 G9.298 2.98E−01 29.1 LYM130 12333.1 K 0.495 7.48E−01 4 LYM62 12022.2 G8.814 3.09E−01 22.3 LYM16 11624.4 K 0.492 7.53E−01 3.4 LYM119 12462.1 G7.626 3.21E−01 5.8 LYM143 12521.1 K 0.494 7.62E−01 3.8 LYM172 12301.2 G8.25 3.22E−01 14.5 LYM129 12571.3 K 0.493 7.92E−01 3.7 LYM143 12521.2 G9.228 3.24E−01 28.1 LYM13 11772.2 K 0.488 8.40E−01 2.6 LYM31 11924.4 G8.269 3.35E−01 14.8 LYM9 11633.2 K 0.486 8.54E−01 2.2 LYM14 12052.5 G8.091 3.45E−01 12.3 LYM290 12502.1 K 0.487 8.54E−01 2.4 LYM62 12021.1 G8.695 3.46E−01 20.7 LYM9 11634.5 K 0.484 8.82E−01 1.7 LYM53 11841.1 G9.045 3.63E−01 25.6 LYM106 12144.4 K 0.484 8.84E−01 1.8 LYM67 11782.5 G7.534 3.65E−01 4.6 LYM174 12411.3 K 0.485 8.98E−01 1.9 LYM119 12461.1 G8.655 3.72E−01 20.1 LYM268 12483.4 K 0.482 9.01E−01 1.5 LYM30 11912.6 G7.91 3.80E−01 9.8 LYM129 12572.2 K 0.481 9.19E−01 1.2 LYM30 11913.4 G14.939 3.98E−01 107.4 LYM134 12311.2 K 0.48 9.39E−01 0.9 LYM254 12471.2G 8.136 4.05E−01 12.9 LYM9 11633.7 K 0.48 9.41E−01 0.8 LYM24 12061.2 G8.905 4.08E−01 23.6 LYM13 11771.9 K 0.479 9.49E−01 0.7 LYM53 11844.2 G8.516 4.19E−01 18.2 LYM137 12151.1 K 0.479 9.51E−01 0.7 LYM130 12333.1 G8.44 4.29E−01 17.1 LYM134 12312.3 K 0.478 9.61E−01 0.6 LYM51 11893.2 G8.6 4.35E−01 19.4 LYM162 12231.3 K 0.478 9.64E−01 0.6 LYM51 11892.1 G8.007 4.43E−01 11.1 LYM2 11693.3 K 0.477 9.81E−01 0.3 LYM26 11824.3 G7.467 4.44E−01 3.6 CONTROL — K 0.476 — 0 LYM148 12173.1 G 7.909 4.46E−019.8 LYM1 11602.6 L 2.507 2.00E−05 100.5 LYM62 12023.4 G 7.505 4.48E−014.2 LYM10 11741.2 L 2.405 3.80E−05 92.3 LYM170 12453.3 G 8.378 4.85E−0116.3 LYM119 12462.2 L 2.191 8.04E−04 75.2 LYM162 12234.3 G 8.2464.91E−01 14.5 LYM9 11632.1 L 2.134 1.01E−03 70.6 LYM170 12452.3 G 7.894.91E−01 9.5 LYM143 12524.7 L 2.094 1.12E−03 67.4 LYM31 11922.3 G 8.3745.24E−01 16.2 LYM148 12171.2 L 2.033 1.84E−03 62.6 LYM134 12313.2 G8.028 5.29E−01 11.4 LYM138 12561.1 L 2.041 2.32E−03 63.2 LYM153 12321.2G 8.374 5.39E−01 16.2 LYM174 12414.3 L 1.921 9.20E−03 53.6 LYM25412472.3 G 7.445 5.40E−01 3.3 LYM1 11604.4 L 1.853 1.20E−02 48.1 LYM15212371.2 G 8.103 5.47E−01 12.5 LYM102 12222.2 L 1.847 1.29E−02 47.7LYM290 12502.4 G 7.865 5.54E−01 9.2 LYM130 12333.1 L 1.868 1.31E−02 49.3LYM130 12332.2 G 9.594 5.61E−01 33.2 LYM148 12174.1 L 1.84 1.45E−02 47.1LYM172 12302.2 G 7.736 5.61E−01 7.4 LYM289 12493.2 L 1.868 1.45E−02 49.3LYM3 12041.1 G 8.492 5.64E−01 17.9 LYM141 12402.4 L 1.841 1.66E−02 47.2LYM62 12022.4 G 7.949 5.65E−01 10.3 LYM119 12462.1 L 1.841 1.92E−02 47.2LYM130 12331.3 G 7.748 5.70E−01 7.5 LYM10 11742.2 L 1.795 2.33E−02 43.5LYM174 12411.2 G 7.837 5.73E−01 8.8 LYM138 12561.3 L 1.823 2.34E−02 45.8LYM138 12566.1 G 7.716 5.76E−01 7.1 LYM1 11602.1 L 1.792 2.41E−02 43.2LYM14 12052.4 G 7.776 5.91E−01 7.9 LYM105 12293.1 L 1.776 2.81E−02 42LYM43 11791.2 G 8.025 6.07E−01 11.4 LYM174 12411.2 L 1.778 3.09E−02 42.1LYM69 11853.4 G 7.977 6.13E−01 10.7 LYM10 11744.1 L 1.752 3.26E−02 40.1LYM68 11941.4 G 7.693 6.29E−01 6.8 LYM162 12234.4 L 1.838 3.42E−02 47LYM268 12481.1 G 7.844 6.40E−01 8.9 LYM152 12372.2 L 1.744 4.01E−02 39.4LYM43 11793.2 G 8.087 6.72E−01 12.3 LYM4 11706.5 L 1.729 4.16E−02 38.3LYM53 11842.4 G 8.049 6.85E−01 11.7 LYM162 12234.3 L 1.742 4.19E−02 39.3LYM31 11923.1 G 7.713 7.10E−01 7.1 LYM130 12332.2 L 1.717 5.60E−02 37.3LYM148 12172.1 G 7.516 7.34E−01 4.3 LYM19 11751.5 L 1.692 6.21E−02 35.3LYM132 12276.1 G 7.887 7.39E−01 9.5 LYM15 11614.3 L 1.676 6.35E−02 34LYM105 12294.2 G 7.427 7.63E−01 3.1 LYM119 12463.2 L 1.675 7.13E−02 33.9LYM119 12462.2 G 7.294 7.81E−01 1.2 LYM140 12262.3 L 1.658 7.47E−02 32.6LYM53 11841.2 G 7.546 7.89E−01 4.7 LYM15 11612.3 L 1.675 7.83E−02 33.9LYM100 12133.3 G 7.317 7.97E−01 1.6 LYM289 12491.1 L 1.682 8.02E−02 34.5LYM51 11894.2 G 7.296 8.21E−01 1.3 LYM130 12334.1 L 1.658 8.07E−02 32.6LYM119 12461.4 G 7.336 8.46E−01 1.8 LYM19 11751.4 L 1.684 8.28E−02 34.6LYM95 12124.5 G 7.471 8.50E−01 3.7 LYM19 11753.1 L 1.625 1.03E−01 29.9LYM105 12293.1 G 7.467 8.53E−01 3.6 LYM134 12311.2 L 1.64 1.05E−01 31.1LYM254 12474.4 G 7.737 8.61E−01 7.4 LYM162 12231.1 L 1.637 1.06E−01 30.9LYM254 12474.3 G 7.321 8.99E−01 1.6 LYM132 12273.2 L 1.619 1.07E−01 29.5LYM170 12453.2 G 7.239 9.08E−01 0.5 LYM1 11603.2 L 1.614 1.10E−01 29LYM172 12301.3 G 7.319 9.09E−01 1.6 LYM119 12461.4 L 1.613 1.13E−01 29LYM170 12452.4 G 7.249 9.33E−01 0.6 LYM15 11611.3 L 1.633 1.16E−01 30.6LYM69 11852.4 G 7.225 9.80E−01 0.3 LYM17 11684.4 L 1.609 1.17E−01 28.6LYM14 12051.4 G 7.244 9.80E−01 0.6 LYM148 12173.1 L 1.639 1.21E−01 31LYM143 12521.1 G 7.211 9.94E−01 0.1 LYM141 12404.4 L 1.595 1.46E−01 27.6CONTROL — G 7.204 — 0 LYM102 12222.3 L 1.615 1.50E−01 29.1 LYM13812561.1 H 25.053 4.46E−04 61.4 LYM268 12483.2 L 1.569 1.55E−01 25.5LYM134 12314.2 H 23.018 4.64E−04 48.3 LYM162 12231.3 L 1.572 1.57E−0125.7 LYM268 12482.3 H 22.616 7.44E−04 45.7 LYM132 12271.4 L 1.571.71E−01 25.5 LYM43 11791.5 H 23.824 1.69E−03 53.5 LYM152 12371.2 L1.568 1.80E−01 25.4 LYM100 12131.2 H 24.777 2.60E−03 59.6 LYM141 12404.3L 1.56 1.82E−01 24.7 LYM140 12264.1 H 20.454 8.48E−03 31.8 LYM21 11671.2L 1.548 1.95E−01 23.8 LYM68 11942.3 H 21.899 9.46E−03 41.1 LYM9 11633.7L 1.551 1.99E−01 24 LYM57 12013.5 H 21.379 1.02E−02 37.7 LYM17 11682.1 L1.572 2.12E−01 25.7 LYM143 12524.2 H 22.043 1.20E−02 42 LYM105 12294.2 L1.58 2.17E−01 26.3 LYM148 12174.1 H 29.36 1.27E−02 89.1 LYM100 12133.1 L1.52 2.30E−01 21.5 LYM31 11923.4 H 22.007 1.51E−02 41.8 LYM15 11612.2 L1.521 2.35E−01 21.6 LYM170 12453.2 H 19.373 2.87E−02 24.8 LYM111 12251.1L 1.533 2.43E−01 22.6 LYM69 11853.5 H 20.573 3.39E−02 32.5 LYM14312524.2 L 1.515 2.44E−01 21.2 LYM290 12502.4 H 22.469 3.42E−02 44.7LYM21 11673.1 L 1.516 2.45E−01 21.2 LYM130 12331.3 H 18.905 3.44E−0221.8 LYM174 12411.3 L 1.515 2.58E−01 21.1 LYM137 12151.1 H 21.7623.90E−02 40.2 LYM290 12502.4 L 1.517 2.60E−01 21.3 LYM53 11841.1 H 22.545.42E−02 45.2 LYM21 11672.4 L 1.506 2.73E−01 20.4 LYM51 11893.2 H 18.8766.70E−02 21.6 LYM19 11754.1 L 1.491 2.79E−01 19.2 LYM138 12561.3 H23.075 7.08E−02 48.7 LYM290 12501.3 L 1.483 3.11E−01 18.6 LYM148 12171.2H 21.107 7.50E−02 36 LYM174 12412.1 L 1.486 3.12E−01 18.8 LYM119 12462.2H 19.845 8.05E−02 27.8 LYM10 11744.5 L 1.479 3.29E−01 18.2 LYM57 12012.2H 18.127 8.18E−02 16.8 LYM13 11771.6 L 1.476 3.30E−01 18 LYM119 12462.1H 25.604 8.45E−02 64.9 LYM268 12483.4 L 1.478 3.34E−01 18.1 LYM1412052.4 H 18.108 9.10E−02 16.7 LYM9 11632.2 L 1.467 3.38E−01 17.3 LYM6811941.3 H 21.383 9.75E−02 37.7 LYM4 11705.2 L 1.465 3.38E−01 17.1 LYM4311791.4 H 20.159 1.06E−01 29.9 LYM289 12491.4 L 1.464 3.49E−01 17 LYM13712152.1 H 17.811 1.18E−01 14.7 LYM143 12521.1 L 1.453 3.61E−01 16.2LYM105 12294.3 H 18.802 1.43E−01 21.1 LYM141 12404.2 L 1.456 3.64E−0116.4 LYM111 12252.2 H 35.594 1.61E−01 129.3 LYM10 11742.1 L 1.4773.68E−01 18.1 LYM30 11913.5 H 19.962 1.68E−01 28.6 LYM289 12493.6 L1.431 4.07E−01 14.4 LYM268 12481.1 H 18.491 1.73E−01 19.1 LYM102 12221.1L 1.425 4.39E−01 13.9 LYM130 12334.1 H 17.432 1.74E−01 12.3 LYM11112252.2 L 1.441 4.63E−01 15.2 LYM148 12173.1 H 18.318 1.82E−01 18 LYM13812562.1 L 1.407 4.77E−01 12.5 LYM68 11943.2 H 20.473 1.93E−01 31.9LYM137 12153.1 L 1.414 4.85E−01 13.1 LYM137 12154.5 H 19.406 2.03E−01 25LYM268 12482.3 L 1.397 5.07E−01 11.7 LYM152 12372.2 H 17.721 2.08E−0114.2 LYM2 11692.3 L 1.391 5.24E−01 11.2 LYM100 12131.3 H 17.347 2.10E−0111.7 LYM13 11772.1 L 1.385 5.50E−01 10.8 LYM105 12295.2 H 18.6362.16E−01 20.1 LYM129 12573.5 L 1.37 5.85E−01 9.5 LYM130 12332.2 H 19.3962.39E−01 25 LYM162 12233.2 L 1.374 5.94E−01 9.8 LYM290 12501.3 H 18.1762.41E−01 17.1 LYM100 12131.3 L 1.369 6.12E−01 9.5 LYM172 12301.2 H19.401 2.45E−01 25 LYM113 12442.1 L 1.354 6.33E−01 8.2 LYM68 11942.2 H18.84 2.53E−01 21.4 LYM148 12172.1 L 1.368 6.37E−01 9.4 LYM62 12022.1 H18.131 2.65E−01 16.8 LYM17 11681.4 L 1.345 6.69E−01 7.6 LYM57 12012.6 H17.854 2.67E−01 15 LYM268 12482.1 L 1.349 6.71E−01 7.9 LYM111 12251.3 H19.231 2.86E−01 23.9 LYM16 11624.4 L 1.339 6.83E−01 7.1 LYM111 12254.4 H19.709 2.89E−01 27 LYM17 11684.5 L 1.332 7.05E−01 6.5 LYM51 11894.2 H17.123 3.01E−01 10.3 LYM9 11633.2 L 1.334 7.13E−01 6.7 LYM30 11912.6 H20.501 3.16E−01 32.1 LYM174 12414.2 L 1.32 7.47E−01 5.6 LYM53 11844.2 H20.169 3.27E−01 29.9 LYM17 11683.1 L 1.313 7.74E−01 5 LYM132 12271.4 H17.765 3.38E−01 14.4 LYM290 12502.1 L 1.313 7.90E−01 5 LYM62 12021.1 H19.779 3.40E−01 27.4 LYM140 12261.4 L 1.304 8.12E−01 4.2 LYM137 12153.1H 16.796 3.54E−01 8.2 LYM1 11601.1 L 1.303 8.13E−01 4.2 LYM100 12134.1 H17.739 3.54E−01 14.3 LYM102 12222.6 L 1.308 8.19E−01 4.6 LYM152 12376.1H 18.514 3.63E−01 19.3 LYM2 11693.3 L 1.289 8.60E−01 3 LYM51 11893.4 H22.579 3.83E−01 45.5 LYM132 12275.1 L 1.288 8.64E−01 3 LYM100 12133.3 H16.699 4.07E−01 7.6 LYM143 12521.2 L 1.282 8.86E−01 2.5 LYM143 12521.2 H16.583 4.25E−01 6.8 LYM22 11762.1 L 1.28 8.94E−01 2.3 LYM111 12254.3 H22.309 4.38E−01 43.7 LYM143 12523.4 L 1.272 9.24E−01 1.7 LYM14 12051.4 H17.186 4.39E−01 10.7 LYM13 11771.9 L 1.262 9.58E−01 0.9 LYM152 12372.1 H20.578 4.63E−01 32.6 LYM111 12254.4 L 1.262 9.60E−01 0.9 LYM143 12524.7H 23.443 4.73E−01 51 LYM138 12564.1 L 1.251 1.00E+00 0 LYM134 12312.4 H16.924 4.79E−01 9 CONTROL — L 1.251 — 0 LYM290 12502.2 H 19.066 4.84E−0122.8 LYM1 11602.6 M 0.313 3.40E−05 94.2 LYM68 11941.4 H 16.657 4.90E−017.3 LYM10 11741.2 M 0.301 6.50E−05 86.3 LYM119 12461.1 H 23.276 4.91E−0149.9 LYM119 12462.2 M 0.274 1.29E−03 69.7 LYM26 11824.6 H 17.6424.94E−01 13.7 LYM9 11632.1 M 0.267 1.64E−03 65.3 LYM132 12275.1 H 16.5395.07E−01 6.5 LYM143 12524.7 M 0.262 1.85E−03 62.2 LYM67 11783.5 H 17.1095.29E−01 10.2 LYM148 12171.2 M 0.254 3.03E−03 57.5 LYM132 12276.1 H17.095 5.30E−01 10.1 LYM138 12561.1 M 0.255 3.74E−03 58.1 LYM119 12461.4H 16.919 5.75E−01 9 LYM174 12414.3 M 0.24 1.42E−02 48.8 LYM43 11792.2 H17.389 5.90E−01 12 LYM1 11604.4 M 0.232 1.88E−02 43.5 LYM53 11842.4 H18.313 5.93E−01 18 LYM130 12333.1 M 0.233 2.02E−02 44.7 LYM30 11912.7 H16.92 6.04E−01 9 LYM102 12222.2 M 0.231 2.03E−02 43.1 LYM95 12124.4 H16.255 6.19E−01 4.7 LYM289 12493.2 M 0.233 2.20E−02 44.7 LYM138 12562.1H 17.022 6.38E−01 9.7 LYM148 12174.1 M 0.23 2.25E−02 42.5 LYM30 11913.3H 16.514 6.50E−01 6.4 LYM141 12402.4 M 0.23 2.54E−02 42.6 LYM43 11793.2H 17.297 6.59E−01 11.4 LYM119 12462.1 M 0.23 2.88E−02 42.6 LYM16212231.3 H 16.771 6.82E−01 8 LYM138 12561.3 M 0.228 3.48E−02 41.2 LYM6711782.4 H 16.28 6.90E−01 4.9 LYM10 11742.2 M 0.224 3.55E−02 39 LYM2611824.5 H 15.96 7.43E−01 2.8 LYM1 11602.1 M 0.224 3.66E−02 38.8 LYM3111922.3 H 16.061 7.61E−01 3.5 LYM105 12293.1 M 0.222 4.23E−02 37.6LYM152 12371.2 H 16.57 7.69E−01 6.7 LYM174 12411.2 M 0.222 4.59E−02 37.7LYM69 11852.4 H 16.05 7.87E−01 3.4 LYM162 12234.4 M 0.23 4.82E−02 42.4LYM254 12474.4 H 16.855 8.07E−01 8.6 LYM10 11744.1 M 0.219 4.91E−02 35.7LYM111 12251.1 H 15.798 8.44E−01 1.8 LYM152 12372.2 M 0.218 5.92E−0235.1 LYM152 12373.1 H 16.237 8.53E−01 4.6 LYM162 12234.3 M 0.2186.16E−02 34.9 LYM268 12483.2 H 16.06 8.84E−01 3.5 LYM4 11706.5 M 0.2166.18E−02 34 LYM51 11891.1 H 15.71 8.91E−01 1.2 LYM15 11611.3 M 0.2217.09E−02 36.8 LYM172 12302.2 H 15.768 9.46E−01 1.6 LYM130 12332.2 M0.215 8.05E−02 33 LYM66 11954.4 H 15.884 9.47E−01 2.3 LYM19 11751.5 M0.212 8.99E−02 31.1 LYM138 12564.1 H 15.654 9.64E−01 0.8 LYM15 11614.3 M0.21 9.28E−02 29.8 LYM140 12262.3 H 15.652 9.65E−01 0.8 LYM119 12463.2 M0.209 1.02E−01 29.8 LYM290 12502.1 H 15.592 9.67E−01 0.4 LYM132 12271.4M 0.209 1.03E−01 29.8 LYM170 12452.3 H 15.573 9.84E−01 0.3 LYM14012262.3 M 0.207 1.08E−01 28.5 LYM268 12482.1 H 15.528 9.99E−01 0 LYM1511612.3 M 0.209 1.11E−01 29.7 CONTROL — H 15.523 — 0 LYM289 12491.1 M0.21 1.13E−01 30.3 LYM111 12252.2 J 0.075 6.99E−04 88 LYM130 12334.1 M0.207 1.15E−01 28.5 LYM148 12174.1 J 0.06 1.71E−02 51.2 LYM19 11751.4 M0.21 1.16E−01 30.4 LYM100 12131.2 J 0.057 3.78E−02 43.8 LYM19 11753.1 M0.203 1.46E−01 25.9 LYM119 12462.1 J 0.057 4.39E−02 42.8 LYM134 12311.2M 0.205 1.46E−01 27 LYM134 12314.2 J 0.056 5.26E−02 40.2 LYM162 12231.1M 0.205 1.48E−01 26.8 LYM138 12561.1 J 0.056 5.33E−02 40.8 LYM13212273.2 M 0.202 1.51E−01 25.4 LYM53 11841.1 J 0.053 1.00E−01 33.8 LYM111603.2 M 0.202 1.55E−01 25 LYM119 12461.1 J 0.055 1.12E−01 39 LYM11912461.4 M 0.202 1.59E−01 24.9 LYM43 11791.5 J 0.052 1.28E−01 30.7 LYM14812173.1 M 0.205 1.64E−01 26.9 LYM143 12524.2 J 0.052 1.29E−01 30.9 LYM1711684.4 M 0.201 1.64E−01 24.6 LYM138 12561.3 J 0.052 1.37E−01 31 LYM14112404.4 M 0.199 1.99E−01 23.6 LYM268 12482.3 J 0.052 1.50E−01 29.7LYM102 12222.3 M 0.202 2.01E−01 25.1 LYM51 11893.4 J 0.052 1.68E−01 31.2LYM174 12412.1 M 0.201 2.06E−01 24.5 LYM170 12453.2 J 0.05 1.80E−01 26.5LYM268 12483.2 M 0.196 2.14E−01 21.6 LYM148 12171.2 J 0.05 1.84E−01 25.8LYM162 12231.3 M 0.196 2.16E−01 21.8 LYM290 12502.4 J 0.051 1.91E−0127.3 LYM4 11705.2 M 0.197 2.21E−01 22.2 LYM69 11853.5 J 0.05 1.99E−0125.8 LYM152 12371.2 M 0.196 2.42E−01 21.5 LYM143 12524.7 J 0.0522.03E−01 30.5 LYM141 12404.3 M 0.195 2.46E−01 20.8 LYM152 12372.1 J0.051 2.08E−01 27.9 LYM21 11671.2 M 0.194 2.63E−01 19.9 LYM31 11923.4 J0.049 2.30E−01 23.8 LYM9 11633.7 M 0.194 2.66E−01 20.2 LYM62 12021.1 J0.049 2.47E−01 23.5 LYM17 11682.1 M 0.196 2.76E−01 21.7 LYM68 11941.3 J0.049 2.49E−01 22.7 LYM105 12294.2 M 0.197 2.79E−01 22.4 LYM68 11942.3 J0.049 2.51E−01 22.9 LYM100 12133.1 M 0.19 3.08E−01 17.7 LYM30 11912.6 J0.049 2.52E−01 23.6 LYM15 11612.2 M 0.19 3.12E−01 17.8 LYM137 12151.1 J0.049 2.56E−01 23 LYM111 12251.1 M 0.192 3.17E−01 18.8 LYM111 12254.3 J0.05 2.65E−01 26.4 LYM143 12524.2 M 0.189 3.24E−01 17.4 LYM137 12154.5 J0.049 2.67E−01 22.6 LYM21 11673.1 M 0.19 3.25E−01 17.4 LYM43 11791.4 J0.047 3.56E−01 18.4 LYM174 12411.3 M 0.189 3.38E−01 17.3 LYM57 12013.5 J0.047 3.61E−01 17.9 LYM290 12502.4 M 0.19 3.39E−01 17.5 LYM53 11844.2 J0.047 3.67E−01 18.8 LYM21 11672.4 M 0.188 3.57E−01 16.6 LYM30 11913.5 J0.047 3.74E−01 18.1 LYM19 11754.1 M 0.186 3.68E−01 15.5 LYM172 12301.2 J0.047 3.74E−01 17.8 LYM290 12501.3 M 0.185 4.02E−01 14.9 LYM140 12264.1J 0.046 4.03E−01 16.5 LYM10 11744.5 M 0.185 4.23E−01 14.5 LYM111 12251.3J 0.046 4.13E−01 16.2 LYM13 11771.6 M 0.184 4.24E−01 14.3 LYM105 12294.3J 0.046 4.21E−01 15.8 LYM268 12483.4 M 0.185 4.28E−01 14.5 LYM11912462.2 J 0.046 4.34E−01 16.2 LYM9 11632.2 M 0.183 4.36E−01 13.6 LYM29012502.2 J 0.047 4.34E−01 16.7 LYM289 12491.4 M 0.183 4.48E−01 13.4 LYM6811943.2 J 0.046 4.46E−01 15 LYM10 11742.1 M 0.185 4.60E−01 14.4 LYM26812481.1 J 0.046 4.64E−01 14.3 LYM143 12521.1 M 0.182 4.66E−01 12.6LYM137 12153.1 J 0.046 4.66E−01 14.7 LYM141 12404.2 M 0.182 4.66E−0112.7 LYM137 12152.1 J 0.046 4.76E−01 14.3 LYM289 12493.6 M 0.1795.20E−01 10.9 LYM111 12254.4 J 0.045 5.19E−01 12.8 LYM17 11681.4 M 0.1795.21E−01 11 LYM67 11783.5 J 0.045 5.24E−01 13.1 LYM102 12221.1 M 0.1785.52E−01 10.4 LYM14 12052.4 J 0.045 5.38E−01 12 LYM111 12252.2 M 0.185.64E−01 11.6 LYM152 12376.1 J 0.045 5.55E−01 11.7 LYM138 12562.1 M0.176 5.99E−01 9 LYM57 12012.2 J 0.044 5.56E−01 11.6 LYM137 12153.1 M0.177 5.99E−01 9.6 LYM43 11792.2 J 0.045 5.60E−01 11.9 LYM268 12482.3 M0.175 6.31E−01 8.3 LYM68 11942.2 J 0.044 6.17E−01 9.8 LYM2 11692.3 M0.174 6.50E−01 7.8 LYM134 12312.4 J 0.043 6.74E−01 8.3 LYM13 11772.1 M0.173 6.76E−01 7.3 LYM138 12562.1 J 0.043 6.85E−01 7.9 LYM129 12573.5 M0.171 7.18E−01 6.1 LYM105 12295.2 J 0.043 6.88E−01 7.9 LYM162 12233.2 M0.172 7.20E−01 6.4 LYM152 12372.2 J 0.043 6.89E−01 7.7 LYM100 12131.3 M0.171 7.38E−01 6.1 LYM254 12474.4 J 0.043 7.03E−01 8.3 LYM148 12172.1 M0.171 7.57E−01 6 LYM51 11893.2 J 0.043 7.27E−01 6.7 LYM113 12442.1 M0.169 7.72E−01 4.9 LYM57 12012.6 J 0.043 7.31E−01 6.8 LYM268 12482.1 M0.169 8.03E−01 4.5 LYM119 12461.4 J 0.043 7.38E−01 6.7 LYM16 11624.4 M0.167 8.24E−01 3.7 LYM100 12134.1 J 0.042 7.60E−01 6 LYM17 11684.5 M0.167 8.48E−01 3.2 LYM132 12276.1 J 0.042 7.61E−01 5.8 LYM9 11633.2 M0.167 8.49E−01 3.4 LYM290 12501.3 J 0.042 7.65E−01 5.8 LYM174 12414.2 M0.165 8.92E−01 2.3 LYM62 12022.1 J 0.042 7.73E−01 5.6 LYM17 11683.1 M0.164 9.20E−01 1.7 LYM26 11824.6 J 0.042 7.80E−01 5.3 LYM290 12502.1 M0.164 9.25E−01 1.7 LYM51 11891.1 J 0.042 8.08E−01 4.6 LYM102 12222.6 M0.163 9.46E−01 1.3 LYM43 11793.2 J 0.042 8.24E−01 4.5 LYM140 12261.4 M0.163 9.55E−01 1 LYM100 12131.3 J 0.041 8.31E−01 4 LYM1 11601.1 M 0.1639.57E−01 0.9 LYM143 12521.2 J 0.041 8.39E−01 3.9 CONTROL — M 0.161 — 0LYM132 12275.1 J 0.041 8.53E−01 3.6 LYM10 11741.2 N 0.274 1.39E−04 51LYM100 12133.3 J 0.041 8.80E−01 2.9 LYM9 11632.1 N 0.272 1.71E−04 49.7LYM51 11894.2 J 0.041 8.81E−01 2.9 LYM1 11602.6 N 0.27 1.78E−04 48.6LYM67 11782.4 J 0.041 8.84E−01 2.9 LYM143 12524.7 N 0.267 4.23E−04 46.9LYM14 12051.4 J 0.041 8.90E−01 2.7 LYM119 12462.2 N 0.252 5.22E−03 38.9LYM53 11842.4 J 0.041 9.19E−01 2.1 LYM10 11742.2 N 0.236 1.12E−02 29.9LYM172 12302.2 J 0.04 9.57E−01 1.1 LYM289 12493.2 N 0.235 1.37E−02 29.4LYM130 12331.3 J 0.04 9.66E−01 0.8 LYM174 12414.3 N 0.238 1.53E−02 30.8LYM268 12482.1 J 0.04 9.71E−01 0.7 LYM148 12171.2 N 0.234 1.54E−02 29LYM132 12271.4 J 0.04 9.73E−01 0.7 LYM105 12293.1 N 0.233 1.86E−02 28LYM162 12231.3 J 0.04 9.76E−01 0.6 LYM138 12561.1 N 0.235 1.90E−02 29.3LYM14 12051.1 J 0.04 9.76E−01 0.6 LYM102 12222.2 N 0.231 2.04E−02 27.3LYM30 11912.7 J 0.04 9.77E−01 0.6 LYM148 12174.1 N 0.23 2.20E−02 26.7LYM69 11854.2 J 0.04 9.77E−01 0.5 LYM130 12333.1 N 0.232 2.21E−02 27.5LYM152 12373.1 J 0.04 9.81E−01 0.5 LYM162 12234.3 N 0.231 2.61E−02 27.1LYM148 12173.1 J 0.04 9.85E−01 0.4 LYM1 11604.4 N 0.23 2.80E−02 26.7CONTROL — J 0.04 — 0 LYM15 11614.3 N 0.227 3.23E−02 25.2 LYM67 11783.5 K0.741 6.72E−04 44.8 LYM152 12372.2 N 0.228 3.31E−02 25.6 LYM132 12276.1K 0.696 1.12E−02 36 LYM162 12234.4 N 0.236 3.39E−02 30 LYM138 12566.1 K0.659 1.33E−02 28.9 LYM141 12402.4 N 0.226 4.06E−02 24.5 LYM119 12461.1K 0.671 1.72E−02 31.2 LYM134 12311.2 N 0.226 4.65E−02 24.2 LYM69 11853.5K 0.657 2.56E−02 28.4 LYM19 11751.5 N 0.223 4.82E−02 22.9 LYM137 12151.1K 0.648 2.68E−02 26.8 LYM10 11744.1 N 0.224 4.91E−02 23.5 LYM138 12561.1K 0.638 3.91E−02 24.7 LYM1 11602.1 N 0.224 5.06E−02 23.2 LYM105 12297.1K 0.646 4.88E−02 26.3 LYM132 12271.4 N 0.221 5.78E−02 21.8 LYM30 11913.3K 0.631 5.27E−02 23.3 LYM174 12411.2 N 0.223 5.88E−02 22.8 LYM53 11841.1K 0.641 5.90E−02 25.3 LYM140 12262.3 N 0.221 6.40E−02 21.4 LYM11112251.1 K 0.627 6.03E−02 22.5 LYM119 12461.4 N 0.22 7.17E−02 21.3 LYM2412061.2 K 0.631 6.18E−02 23.3 LYM4 11706.5 N 0.219 8.19E−02 20.4 LYM2412064.1 K 0.618 6.89E−02 20.9 LYM15 11611.3 N 0.224 8.23E−02 23.1 LYM25412471.2 K 0.615 7.20E−02 20.3 LYM130 12332.2 N 0.222 8.28E−02 22.3 LYM3111923.1 K 0.617 8.28E−02 20.6 LYM268 12483.2 N 0.217 9.09E−02 19.5 LYM5712013.5 K 0.617 8.35E−02 20.7 LYM174 12412.1 N 0.22 9.27E−02 20.8 LYM10512295.2 K 0.62 8.37E−02 21.2 LYM162 12231.1 N 0.217 1.07E−01 19.4 LYM10512293.1 K 0.611 8.53E−02 19.5 LYM19 11751.4 N 0.218 1.07E−01 19.8 LYM5111893.2 K 0.62 8.98E−02 21.3 LYM138 12561.3 N 0.217 1.08E−01 19.3 LYM6212022.1 K 0.612 9.67E−02 19.7 LYM141 12404.4 N 0.217 1.08E−01 19.3 LYM6811942.3 K 0.605 1.06E−01 18.2 LYM19 11753.1 N 0.214 1.09E−01 18.1 LYM14812174.1 K 0.615 1.10E−01 20.3 LYM174 12411.3 N 0.217 1.15E−01 19.2LYM111 12254.4 K 0.614 1.13E−01 20.1 LYM132 12273.2 N 0.213 1.19E−0117.4 LYM268 12482.3 K 0.616 1.16E−01 20.4 LYM17 11684.4 N 0.214 1.19E−0117.9 LYM111 12252.2 K 0.609 1.28E−01 19.1 LYM4 11705.2 N 0.215 1.21E−0118.1 LYM67 11782.5 K 0.602 1.28E−01 17.6 LYM15 11612.3 N 0.217 1.25E−0119.3 LYM62 12023.4 K 0.606 1.29E−01 18.4 LYM9 11632.2 N 0.215 1.26E−0118.3 LYM148 12172.1 K 0.601 1.35E−01 17.5 LYM119 12462.1 N 0.2161.29E−01 18.6 LYM143 12524.2 K 0.605 1.51E−01 18.2 LYM21 11673.1 N 0.2131.36E−01 17.4 LYM138 12564.1 K 0.616 1.54E−01 20.4 LYM290 12501.3 N0.216 1.42E−01 18.7 LYM134 12311.2 K 0.599 1.66E−01 17.1 LYM130 12334.1N 0.213 1.48E−01 17.3 LYM26 11824.6 K 0.602 1.76E−01 17.6 LYM17 11682.1N 0.217 1.52E−01 19.2 LYM290 12504.1 K 0.596 1.83E−01 16.5 LYM16212231.3 N 0.211 1.58E−01 16.2 LYM95 12124.4 K 0.591 1.85E−01 15.5 LYM10012133.1 N 0.21 1.59E−01 15.8 LYM153 12321.2 K 0.595 1.94E−01 16.4 LYM1911754.1 N 0.211 1.60E−01 15.9 LYM170 12453.2 K 0.585 2.40E−01 14.3LYM148 12173.1 N 0.214 1.61E−01 17.8 LYM30 11913.5 K 0.585 2.41E−01 14.3LYM137 12153.1 N 0.21 1.80E−01 15.8 LYM119 12462.2 K 0.586 2.44E−01 14.7LYM138 12562.1 N 0.208 1.95E−01 14.6 LYM143 12524.7 K 0.6 2.47E−01 17.4LYM102 12221.1 N 0.208 1.97E−01 14.5 LYM172 12302.2 K 0.578 2.79E−01 13LYM15 11612.2 N 0.208 2.06E−01 14.6 LYM68 11943.2 K 0.583 2.80E−01 14LYM13 11772.1 N 0.209 2.08E−01 14.9 LYM132 12275.1 K 0.585 2.80E−01 14.3LYM1 11601.1 N 0.209 2.18E−01 15.2 LYM66 11955.2 K 0.575 2.85E−01 12.4LYM143 12521.1 N 0.207 2.19E−01 14 LYM290 12502.2 K 0.577 2.87E−01 12.8LYM152 12371.2 N 0.208 2.27E−01 14.5 LYM140 12261.1 K 0.598 2.92E−0116.8 LYM289 12491.4 N 0.206 2.34E−01 13.6 LYM290 12502.1 K 0.5782.94E−01 13 LYM1 11603.2 N 0.205 2.45E−01 13 LYM134 12314.2 K 0.5752.95E−01 12.4 LYM268 12483.4 N 0.208 2.49E−01 14.4 LYM62 12021.1 K 0.5793.02E−01 13.2 LYM21 11672.4 N 0.207 2.55E−01 14 LYM14 12052.5 K 0.5743.05E−01 12.2 LYM289 12493.6 N 0.205 2.58E−01 12.7 LYM95 12121.2 K 0.5733.13E−01 12 LYM21 11671.2 N 0.206 2.59E−01 13.3 LYM268 12481.1 K 0.5753.22E−01 12.5 LYM111 12251.1 N 0.207 2.60E−01 13.9 LYM69 11854.2 K 0.573.32E−01 11.5 LYM119 12463.2 N 0.205 2.61E−01 12.9 LYM62 12022.2 K 0.5743.34E−01 12.2 LYM10 11744.5 N 0.206 2.65E−01 13.5 LYM30 11912.7 K 0.5743.35E−01 12.3 LYM148 12172.1 N 0.209 2.78E−01 15 LYM69 11853.4 K 0.5783.42E−01 13 LYM141 12404.2 N 0.203 2.88E−01 11.9 LYM132 12275.3 K 0.5693.42E−01 11.2 LYM13 11771.6 N 0.205 2.89E−01 12.6 LYM130 12333.1 K 0.5653.66E−01 10.6 LYM141 12404.3 N 0.204 2.94E−01 12.1 LYM105 12294.2 K0.563 3.67E−01 10.1 LYM102 12222.3 N 0.207 3.08E−01 14.2 LYM31 11922.3 K0.567 3.69E−01 10.8 LYM289 12491.1 N 0.206 3.10E−01 13.2 LYM170 12453.3K 0.568 3.72E−01 11.1 LYM17 11681.4 N 0.202 3.14E−01 11.3 LYM254 12473.1K 0.563 4.05E−01 10 LYM268 12482.3 N 0.203 3.18E−01 11.5 LYM31 11924.4 K0.57 4.08E−01 11.4 LYM162 12233.2 N 0.202 3.39E−01 11.3 LYM152 12376.1 K0.564 4.22E−01 10.3 LYM174 12414.2 N 0.201 3.47E−01 10.8 LYM57 12012.2 K0.565 4.26E−01 10.4 LYM16 11624.4 N 0.2 3.59E−01 10.2 LYM14 12051.4 K0.56 4.29E−01 9.5 LYM129 12573.5 N 0.2 3.63E−01 10.2 LYM140 12261.4 K0.557 4.32E−01 9 LYM290 12502.4 N 0.202 3.73E−01 11.1 LYM130 12334.1 K0.558 4.46E−01 9.1 LYM268 12482.1 N 0.198 4.54E−01 9 LYM137 12154.5 K0.556 4.67E−01 8.7 LYM105 12294.2 N 0.2 4.70E−01 10 LYM100 12131.3 K0.557 4.69E−01 9 LYM132 12275.3 N 0.2 4.79E−01 10 LYM53 11841.2 K 0.5584.74E−01 9.2 LYM19 11752.2 N 0.197 4.82E−01 8.5 LYM268 12483.4 K 0.5654.77E−01 10.4 LYM143 12524.2 N 0.196 4.88E−01 7.8 LYM68 11941.3 K 0.5554.80E−01 8.6 LYM9 11633.7 N 0.196 4.90E−01 8.1 LYM170 12452.4 K 0.5594.81E−01 9.3 LYM153 12321.2 N 0.196 5.19E−01 7.7 LYM148 12173.1 K 0.5554.86E−01 8.5 LYM111 12254.4 N 0.195 5.30E−01 7.1 LYM268 12482.1 K 0.5584.94E−01 9.1 LYM132 12275.1 N 0.194 5.34E−01 7 LYM26 11821.2 K 0.565.00E−01 9.4 LYM143 12521.2 N 0.194 5.39E−01 6.9 LYM31 11921.3 K 0.5585.05E−01 9.1 LYM10 11742.1 N 0.196 5.54E−01 7.8 LYM31 11923.4 K 0.5545.08E−01 8.3 LYM102 12222.6 N 0.196 5.56E−01 7.9 LYM153 12322.1 K 0.565.10E−01 9.5 LYM13 11771.9 N 0.193 5.98E−01 6.2 LYM30 11913.4 K 0.5495.23E−01 7.4 LYM113 12442.1 N 0.192 6.01E−01 5.9 LYM53 11844.2 K 0.5525.40E−01 7.9 LYM2 11693.3 N 0.192 6.18E−01 5.7 LYM138 12561.3 K 0.5515.44E−01 7.7 LYM140 12261.4 N 0.191 6.66E−01 4.9 LYM152 12372.1 K 0.5525.48E−01 7.9 LYM16 11622.2 N 0.19 6.70E−01 4.8 LYM24 12061.4 K 0.5485.49E−01 7.2 LYM130 12331.3 N 0.189 7.24E−01 4.2 LYM172 12304.2 K 0.5525.50E−01 7.8 LYM100 12131.3 N 0.189 7.44E−01 3.9 LYM148 12174.2 K 0.5525.65E−01 7.9 LYM2 11692.3 N 0.188 7.48E−01 3.6 LYM254 12474.3 K 0.555.67E−01 7.6 LYM138 12564.1 N 0.188 7.56E−01 3.5 LYM51 11891.1 K 0.5435.74E−01 6.2 LYM111 12252.2 N 0.189 7.61E−01 4.2 LYM152 12371.2 K 0.5485.75E−01 7.2 LYM106 12141.4 N 0.188 7.62E−01 3.5 LYM43 11793.2 K 0.555.77E−01 7.6 LYM141 12404.1 N 0.187 7.90E−01 3 LYM152 12373.1 K 0.555.98E−01 7.6 LYM289 12492.2 N 0.187 8.07E−01 2.9 LYM254 12474.4 K 0.5466.00E−01 6.7 LYM153 12324.2 N 0.187 8.23E−01 2.9 LYM67 11781.5 K 0.5426.09E−01 6 LYM17 11684.5 N 0.185 8.58E−01 2 LYM43 11791.5 K 0.5456.10E−01 6.6 LYM119 12461.1 N 0.185 8.84E−01 1.7 LYM51 11892.1 K 0.5436.25E−01 6.2 LYM143 12523.4 N 0.185 8.92E−01 1.6 LYM100 12131.2 K 0.5416.31E−01 5.8 LYM9 11633.2 N 0.184 9.21E−01 1.3 LYM143 12521.2 K 0.5396.33E−01 5.4 LYM17 11683.1 N 0.183 9.35E−01 0.9 LYM162 12231.1 K 0.5396.33E−01 5.4 LYM106 12142.2 N 0.182 9.73E−01 0.4 LYM143 12521.1 K 0.5396.47E−01 5.4 LYM22 11764.1 N 0.182 9.75E−01 0.4 LYM67 11782.6 K 0.5396.49E−01 5.4 LYM22 11762.1 N 0.182 9.78E−01 0.3 LYM53 11843.2 K 0.546.70E−01 5.5 LYM140 12264.1 N 0.182 9.80E−01 0.3 LYM26 11824.5 K 0.5366.75E−01 4.7 LYM153 12323.2 N 0.182 9.81E−01 0.3 LYM130 12332.1 K 0.5426.78E−01 5.9 LYM106 12144.4 N 0.182 9.82E−01 0.3 LYM66 11952.1 K 0.5356.92E−01 4.6 LYM105 12294.3 N 0.182 9.87E−01 0.2 LYM100 12133.3 K 0.5337.11E−01 4.2 CONTROL — N 0.182 — 0 LYM290 12502.4 K 0.534 7.21E−01 4.4LYM143 12524.7 O 2.008 1.50E−05 58.2 LYM162 12234.3 K 0.533 7.24E−01 4.2LYM148 12171.2 O 2.014 2.00E−05 58.6 LYM174 12414.3 K 0.533 7.34E−01 4.2LYM130 12333.1 O 1.851 7.90E−05 45.8 LYM143 12523.4 K 0.532 7.42E−01 3.9LYM10 11741.2 O 2.339 1.39E−04 84.2 LYM14 12051.1 K 0.531 7.52E−01 3.8LYM4 11706.5 O 1.759 2.95E−04 38.5 LYM140 12262.3 K 0.531 7.59E−01 3.8LYM102 12222.2 O 1.761 3.14E−04 38.7 LYM24 12063.3 K 0.529 7.68E−01 3.5LYM1 11602.1 O 1.747 3.45E−04 37.5 LYM43 11791.4 K 0.53 7.70E−01 3.7LYM105 12293.1 O 1.735 4.36E−04 36.6 LYM148 12171.2 K 0.529 7.79E−01 3.4LYM10 11744.1 O 1.731 4.44E−04 36.3 LYM51 11894.2 K 0.529 7.80E−01 3.5LYM162 12234.3 O 1.696 6.35E−04 33.6 LYM174 12411.3 K 0.527 8.03E−01 3LYM140 12262.3 O 1.62 2.10E−03 27.6 LYM153 12323.2 K 0.527 8.05E−01 3LYM132 12271.4 O 1.618 2.28E−03 27.4 LYM268 12483.2 K 0.526 8.15E−01 2.9LYM15 11614.3 O 1.611 2.52E−03 26.9 LYM162 12231.3 K 0.527 8.18E−01 3LYM152 12372.2 O 1.69 8.69E−03 33.1 LYM134 12313.2 K 0.523 8.47E−01 2.3LYM1 11602.6 O 2.435 9.41E−03 91.7 LYM137 12151.2 K 0.523 8.53E−01 2.3LYM119 12461.4 O 1.552 1.28E−02 22.2 LYM14 12054.2 K 0.522 8.56E−01 2.1LYM132 12273.2 O 1.615 1.84E−02 27.2 LYM132 12271.4 K 0.522 8.70E−01 2LYM130 12334.1 O 1.63 2.12E−02 28.4 LYM26 11824.3 K 0.52 8.83E−01 1.7LYM100 12133.1 O 1.499 2.74E−02 18.1 LYM68 11942.2 K 0.52 8.89E−01 1.6LYM289 12493.2 O 1.818 3.54E−02 43.2 LYM134 12312.3 K 0.519 9.12E−01 1.4LYM162 12231.3 O 1.526 3.61E−02 20.2 LYM57 12012.6 K 0.519 9.13E−01 1.4LYM119 12463.2 O 1.666 4.22E−02 31.2 LYM68 11941.4 K 0.518 9.13E−01 1.3LYM138 12561.1 O 2.016 5.07E−02 58.8 LYM95 12124.5 K 0.518 9.25E−01 1.2LYM17 11684.4 O 1.546 5.44E−02 21.7 LYM100 12133.1 K 0.517 9.31E−01 1LYM1 11603.2 O 1.584 5.79E−02 24.8 LYM119 12461.4 K 0.516 9.42E−01 1LYM141 12404.2 O 1.434 7.37E−02 13 LYM152 12372.2 K 0.514 9.65E−01 0.5LYM19 11751.5 O 1.664 1.05E−01 31 LYM140 12264.1 K 0.514 9.70E−01 0.5LYM268 12483.2 O 1.502 1.15E−01 18.3 LYM57 12013.3 K 0.514 9.72E−01 0.4LYM9 11632.1 O 2.069 1.20E−01 63 LYM137 12152.1 K 0.513 9.74E−01 0.4LYM289 12493.6 O 1.403 1.25E−01 10.5 LYM30 11912.6 K 0.513 9.76E−01 0.4LYM1 11604.4 O 1.816 1.26E−01 43 LYM3 12041.1 K 0.513 9.85E−01 0.3LYM148 12174.1 O 1.811 1.28E−01 42.6 LYM119 12462.1 K 0.512 9.90E−01 0.2LYM141 12402.4 O 1.8 1.35E−01 41.8 LYM26 11824.1 K 0.512 9.97E−01 0LYM10 11742.2 O 1.741 1.42E−01 37.1 LYM62 12022.4 K 0.512 9.97E−01 0LYM13 11771.6 O 1.45 1.49E−01 14.2 LYM105 12294.3 K 0.512 9.97E−01 0LYM119 12462.2 O 2.127 1.57E−01 67.5 CONTROL — K 0.511 — 0 LYM10212221.1 O 1.392 1.62E−01 9.6 LYM111 12252.2 L 4.3 3.60E−05 126.4 LYM1911753.1 O 1.586 1.69E−01 24.9 LYM148 12174.1 L 3.579 4.94E−04 88.4 LYM911632.2 O 1.424 1.70E−01 12.1 LYM119 12462.1 L 3.125 7.46E−03 64.5LYM174 12411.2 O 1.753 1.79E−01 38.1 LYM100 12131.2 L 3.041 1.01E−0260.1 LYM17 11681.4 O 1.385 1.88E−01 9.1 LYM138 12561.1 L 3.062 1.03E−0261.2 LYM15 11612.2 O 1.483 2.29E−01 16.8 LYM43 11791.5 L 2.898 1.80E−0252.6 LYM143 12521.1 O 1.407 2.32E−01 10.8 LYM134 12314.2 L 2.8662.55E−02 50.9 LYM19 11754.1 O 1.464 2.44E−01 15.3 LYM138 12561.3 L 2.8453.12E−02 49.8 LYM9 11633.7 O 1.54 2.49E−01 21.3 LYM53 11841.1 L 2.7784.04E−02 46.2 LYM138 12562.1 O 1.364 2.52E−01 7.4 LYM268 12482.3 L 2.7774.10E−02 46.2 LYM130 12332.2 O 1.675 2.61E−01 31.9 LYM290 12502.4 L2.756 5.17E−02 45.1 LYM119 12462.1 O 1.812 2.70E−01 42.7 LYM143 12524.2L 2.7 5.53E−02 42.2 LYM143 12524.2 O 1.482 2.87E−01 16.7 LYM51 11893.4 L2.782 6.14E−02 46.4 LYM174 12414.3 O 1.871 3.05E−01 47.3 LYM137 12151.1L 2.698 6.26E−02 42 LYM138 12561.3 O 1.816 3.10E−01 43 LYM31 11923.4 L2.665 6.28E−02 40.3 LYM113 12442.1 O 1.355 3.16E−01 6.7 LYM143 12524.7 L2.883 6.35E−02 51.8 LYM21 11673.1 O 1.471 3.28E−01 15.9 LYM68 11942.3 L2.659 7.46E−02 40 LYM15 11612.3 O 1.638 3.31E−01 29 LYM119 12461.1 L2.851 7.88E−02 50.1 LYM134 12311.2 O 1.585 3.39E−01 24.8 LYM68 11941.3 L2.631 7.90E−02 38.5 LYM141 12404.3 O 1.532 3.45E−01 20.7 LYM148 12171.2L 2.595 9.52E−02 36.6 LYM19 11751.4 O 1.656 3.52E−01 30.4 LYM57 12013.5L 2.592 9.88E−02 36.4 LYM2 11692.3 O 1.358 3.74E−01 7 LYM111 12254.3 L2.677 1.14E−01 40.9 LYM129 12573.5 O 1.343 3.76E−01 5.7 LYM69 11853.5 L2.545 1.23E−01 34 LYM4 11705.2 O 1.523 3.80E−01 19.9 LYM30 11912.6 L2.527 1.45E−01 33 LYM162 12231.1 O 1.584 3.81E−01 24.7 LYM140 12264.1 L2.495 1.50E−01 31.3 LYM152 12371.2 O 1.538 4.01E−01 21.1 LYM152 12372.1L 2.558 1.54E−01 34.6 LYM15 11611.3 O 1.694 4.12E−01 33.4 LYM68 11943.2L 2.488 1.58E−01 31 LYM21 11671.2 O 1.505 4.27E−01 18.5 LYM43 11791.4 L2.454 1.80E−01 29.2 LYM289 12491.1 O 1.67 4.28E−01 31.5 LYM62 12021.1 L2.449 1.93E−01 28.9 LYM289 12491.4 O 1.423 4.32E−01 12.1 LYM53 11844.2 L2.461 1.95E−01 29.6 LYM141 12404.4 O 1.56 4.38E−01 22.9 LYM30 11913.5 L2.443 1.99E−01 28.6 LYM162 12234.4 O 1.768 4.46E−01 39.2 LYM137 12154.5L 2.438 2.03E−01 28.4 LYM148 12173.1 O 1.605 4.55E−01 26.4 LYM17012453.2 L 2.396 2.19E−01 26.2 LYM290 12501.3 O 1.433 4.56E−01 12.8LYM119 12462.2 L 2.39 2.40E−01 25.8 LYM102 12222.3 O 1.605 5.03E−01 26.4LYM111 12254.4 L 2.399 2.43E−01 26.3 LYM174 12411.3 O 1.491 5.04E−0117.4 LYM172 12301.2 L 2.365 2.52E−01 24.5 LYM174 12412.1 O 1.5545.23E−01 22.4 LYM111 12251.3 L 2.359 2.67E−01 24.2 LYM268 12483.4 O1.434 5.36E−01 13 LYM51 11893.2 L 2.332 2.92E−01 22.8 LYM111 12251.1 O1.498 5.37E−01 18 LYM290 12502.2 L 2.357 2.97E−01 24.1 LYM21 11672.4 O1.466 5.47E−01 15.4 LYM105 12294.3 L 2.305 3.15E−01 21.3 LYM290 12502.4O 1.469 5.82E−01 15.7 LYM130 12332.2 L 2.294 3.24E−01 20.8 LYM10 11744.5O 1.441 5.83E−01 13.5 LYM68 11942.2 L 2.298 3.35E−01 21 LYM13 11772.1 O1.352 5.92E−01 6.5 LYM268 12481.1 L 2.275 3.51E−01 19.7 LYM17 11684.5 O1.314 6.05E−01 3.5 LYM105 12295.2 L 2.277 3.56E−01 19.9 LYM17 11682.1 O1.536 6.12E−01 20.9 LYM130 12331.3 L 2.241 3.81E−01 18 LYM268 12482.3 O1.348 6.33E−01 6.2 LYM148 12173.1 L 2.247 3.93E−01 18.3 LYM16 11624.4 O1.309 6.51E−01 3.1 LYM152 12376.1 L 2.246 3.97E−01 18.2 LYM105 12294.2 O1.536 6.73E−01 21 LYM290 12501.3 L 2.235 4.07E−01 17.7 LYM17 11683.1 O1.306 6.85E−01 2.9 LYM57 12012.2 L 2.225 4.17E−01 17.1 LYM137 12153.1 O1.367 7.39E−01 7.7 LYM132 12276.1 L 2.216 4.40E−01 16.6 LYM111 12252.2 O1.437 7.64E−01 13.1 LYM14 12052.4 L 2.201 4.53E−01 15.9 LYM10 11742.1 O1.418 7.68E−01 11.7 LYM137 12152.1 L 2.204 4.55E−01 16 LYM100 12131.3 O1.351 8.06E−01 6.4 LYM62 12022.1 L 2.195 4.65E−01 15.5 LYM174 12414.2 O1.284 8.53E−01 1.1 LYM100 12134.1 L 2.187 4.81E−01 15.1 LYM9 11633.2 O1.32 8.63E−01 4 LYM26 11824.6 L 2.177 4.90E−01 14.6 LYM162 12233.2 O1.315 8.71E−01 3.6 LYM57 12012.6 L 2.169 5.11E−01 14.2 LYM148 12172.1 O1.349 8.73E−01 6.3 LYM53 11842.4 L 2.179 5.18E−01 14.7 LYM268 12482.1 O1.31 9.06E−01 3.2 LYM67 11783.5 L 2.162 5.19E−01 13.8 LYM140 12261.4 O1.287 9.25E−01 1.3 LYM132 12271.4 L 2.157 5.24E−01 13.5 LYM290 12502.1 O1.301 9.27E−01 2.5 LYM100 12131.3 L 2.141 5.42E−01 12.7 LYM1 11601.1 O1.28 9.68E−01 0.8 LYM152 12372.2 L 2.132 5.59E−01 12.2 LYM22 11762.1 O1.27 9.99E−01 0 LYM138 12562.1 L 2.124 5.80E−01 11.8 CONTROL — O 1.27 —0 LYM43 11792.2 L 2.119 6.05E−01 11.6 LYM143 12524.7 P 2.581 6.00E−06 38LYM51 11894.2 L 2.097 6.19E−01 10.4 LYM148 12171.2 P 2.422 1.00E−04 29.5LYM130 12334.1 L 2.082 6.35E−01 9.6 LYM148 12174.1 P 2.324 1.00E−04 24.2LYM43 11793.2 L 2.092 6.44E−01 10.1 LYM4 11706.5 P 2.302 1.40E−04 23.1LYM134 12312.4 L 2.082 6.55E−01 9.6 LYM10 11744.1 P 2.297 1.80E−04 22.8LYM14 12051.4 L 2.077 6.58E−01 9.4 LYM105 12293.1 P 2.299 2.18E−04 22.9LYM119 12461.4 L 2.072 6.66E−01 9.1 LYM10 11742.2 P 2.364 3.58E−04 26.4LYM132 12275.1 L 2.065 6.78E−01 8.7 LYM102 12222.2 P 2.243 6.39E−04 19.9LYM30 11912.7 L 2.057 6.96E−01 8.3 LYM132 12273.2 P 2.215 6.83E−04 18.4LYM162 12231.3 L 2.056 7.00E−01 8.2 LYM132 12271.4 P 2.21 7.22E−04 18.2LYM137 12153.1 L 2.054 7.02E−01 8.1 LYM130 12333.1 P 2.374 9.53E−04 26.9LYM254 12474.4 L 2.066 7.04E−01 8.8 LYM140 12262.3 P 2.186 1.21E−03 16.9LYM143 12521.2 L 2.049 7.08E−01 7.8 LYM1 11602.1 P 2.253 3.80E−03 20.4LYM100 12133.3 L 2.035 7.35E−01 7.1 LYM162 12234.3 P 2.292 6.47E−03 22.6LYM30 11913.3 L 2.027 7.48E−01 6.7 LYM130 12334.1 P 2.193 9.35E−03 17.3LYM68 11941.4 L 2.013 7.74E−01 6 LYM19 11751.5 P 2.254 9.64E−03 20.5LYM152 12371.2 L 2.012 7.89E−01 5.9 LYM13 11771.6 P 2.078 1.10E−02 11.1LYM67 11782.4 L 1.991 8.22E−01 4.8 LYM289 12493.2 P 2.347 1.26E−02 25.5LYM26 11824.5 L 1.973 8.52E−01 3.9 LYM119 12463.2 P 2.166 1.42E−02 15.8LYM138 12564.1 L 1.976 8.53E−01 4 LYM10 11741.2 P 2.729 1.57E−02 45.9LYM51 11891.1 L 1.972 8.55E−01 3.8 LYM102 12221.1 P 2.058 1.68E−02 10.1LYM152 12373.1 L 1.976 8.56E−01 4 LYM152 12372.2 P 2.243 2.00E−02 20LYM95 12124.4 L 1.962 8.74E−01 3.3 LYM17 11684.4 P 2.111 2.86E−02 12.9LYM268 12483.2 L 1.962 8.79E−01 3.3 LYM1 11602.6 P 2.691 3.00E−02 43.9LYM31 11922.3 L 1.959 8.80E−01 3.1 LYM141 12404.2 P 2.03 3.41E−02 8.5LYM172 12302.2 L 1.948 9.08E−01 2.6 LYM15 11612.2 P 2.083 3.48E−02 11.4LYM14 12051.1 L 1.944 9.11E−01 2.4 LYM143 12524.2 P 2.026 3.61E−02 8.3LYM69 11852.4 L 1.939 9.21E−01 2.1 LYM13 11772.1 P 2.061 3.72E−02 10.2LYM111 12251.1 L 1.936 9.27E−01 1.9 LYM143 12521.1 P 2.054 4.46E−02 9.8LYM66 11954.4 L 1.922 9.59E−01 1.2 LYM100 12133.1 P 2.12 4.61E−02 13.4LYM105 12297.1 L 1.912 9.76E−01 0.6 LYM16 11624.4 P 2.014 4.89E−02 7.7LYM140 12262.3 L 1.906 9.87E−01 0.3 LYM17 11681.4 P 2.019 5.10E−02 8LYM290 12502.1 L 1.906 9.88E−01 0.3 LYM19 11753.1 P 2.149 5.24E−02 14.9CONTROL — L 1.9 — 0 LYM138 12562.1 P 2.008 6.33E−02 7.3 LYM111 12252.2 M0.537 2.20E−05 121 LYM1 11603.2 P 2.096 8.89E−02 12.1 LYM148 12174.1 M0.447 3.03E−04 84 LYM9 11632.1 P 2.655 9.51E−02 42 LYM119 12462.1 M0.391 5.76E−03 60.6 LYM119 12461.4 P 2.172 9.96E−02 16.1 LYM100 12131.2M 0.38 7.86E−03 56.3 LYM129 12573.5 P 1.989 1.00E−01 6.3 LYM138 12561.1M 0.383 8.16E−03 57.4 LYM19 11754.1 P 2.125 1.17E−01 13.6 LYM43 11791.5M 0.362 1.43E−02 49 LYM174 12411.2 P 2.287 1.23E−01 22.3 LYM134 12314.2M 0.358 2.14E−02 47.3 LYM113 12442.1 P 2.054 1.24E−01 9.8 LYM138 12561.3M 0.356 2.71E−02 46.2 LYM141 12402.4 P 2.33 1.29E−01 24.6 LYM119 12461.1M 0.373 3.52E−02 53.4 LYM15 11614.3 P 2.232 1.30E−01 19.4 LYM53 11841.1M 0.347 3.56E−02 42.8 LYM289 12493.6 P 2.051 1.31E−01 9.7 LYM268 12482.3M 0.347 3.61E−02 42.7 LYM9 11632.2 P 2.113 1.36E−01 13 LYM290 12502.4 M0.344 4.73E−02 41.6 LYM138 12561.1 P 2.47 1.39E−01 32 LYM143 12524.2 M0.338 4.96E−02 38.8 LYM119 12462.2 P 2.519 1.48E−01 34.7 LYM31 11923.4 M0.333 5.67E−02 37 LYM9 11633.7 P 2.102 1.55E−01 12.4 LYM137 12151.1 M0.337 5.76E−02 38.7 LYM162 12231.1 P 2.163 1.88E−01 15.6 LYM51 11893.4 M0.348 5.87E−02 43 LYM162 12231.3 P 2.128 1.99E−01 13.8 LYM143 12524.7 M0.36 6.28E−02 48.2 LYM4 11705.2 P 2.127 2.10E−01 13.8 LYM68 11942.3 M0.332 6.98E−02 36.7 LYM141 12404.3 P 2.098 2.18E−01 12.2 LYM68 11941.3 M0.329 7.35E−02 35.2 LYM174 12414.3 P 2.424 2.25E−01 29.6 LYM148 12171.2M 0.324 9.03E−02 33.4 LYM1 11604.4 P 2.316 2.37E−01 23.8 LYM57 12013.5 M0.324 9.44E−02 33.2 LYM19 11751.4 P 2.199 2.40E−01 17.6 LYM170 12453.2 M0.321 9.97E−02 31.9 LYM289 12491.4 P 2.033 2.41E−01 8.7 LYM111 12254.3 M0.335 1.15E−01 37.6 LYM138 12561.3 P 2.306 2.48E−01 23.3 LYM69 11853.5 M0.318 1.20E−01 30.8 LYM134 12311.2 P 2.178 2.62E−01 16.5 LYM30 11912.6 M0.316 1.45E−01 29.9 LYM130 12332.2 P 2.28 2.65E−01 21.9 LYM140 12264.1 M0.312 1.48E−01 28.2 LYM21 11673.1 P 2.114 2.76E−01 13 LYM152 12372.1 M0.32 1.56E−01 31.5 LYM152 12371.2 P 2.127 2.84E−01 13.7 LYM68 11943.2 M0.311 1.58E−01 27.9 LYM119 12462.1 P 2.281 3.03E−01 21.9 LYM43 11791.4 M0.307 1.81E−01 26.1 LYM268 12483.2 P 2.121 3.07E−01 13.4 LYM62 12021.1 M0.306 1.96E−01 25.9 LYM174 12414.2 P 2.016 3.46E−01 7.8 LYM53 11844.2 M0.308 1.99E−01 26.5 LYM174 12411.3 P 2.151 3.50E−01 15 LYM30 11913.5 M0.305 2.03E−01 25.6 LYM15 11612.3 P 2.187 3.58E−01 16.9 LYM137 12154.5 M0.305 2.08E−01 25.3 LYM174 12412.1 P 2.155 3.66E−01 15.2 LYM119 12462.2M 0.299 2.48E−01 22.9 LYM148 12173.1 P 2.153 3.73E−01 15.1 LYM11112254.4 M 0.3 2.52E−01 23.3 LYM141 12404.4 P 2.158 3.80E−01 15.4 LYM17212301.2 M 0.296 2.60E−01 21.6 LYM290 12501.3 P 2.125 3.82E−01 13.6LYM132 12276.1 M 0.295 2.66E−01 21.5 LYM162 12234.4 P 2.296 4.09E−0122.8 LYM111 12251.3 M 0.295 2.78E−01 21.2 LYM111 12251.1 P 2.0984.17E−01 12.2 LYM51 11893.2 M 0.291 3.06E−01 19.9 LYM15 11611.3 P 2.2144.19E−01 18.4 LYM290 12502.2 M 0.295 3.12E−01 21.2 LYM22 11762.1 P 1.9214.32E−01 2.7 LYM67 11783.5 M 0.292 3.23E−01 20 LYM132 12275.1 P 1.9574.42E−01 4.7 LYM105 12294.3 M 0.288 3.31E−01 18.5 LYM21 11671.2 P 2.0794.44E−01 11.1 LYM130 12332.2 M 0.287 3.41E−01 17.9 LYM17 11684.5 P 1.9184.53E−01 2.6 LYM68 11942.2 M 0.287 3.54E−01 18.1 LYM2 11692.3 P 1.9184.54E−01 2.6 LYM268 12481.1 M 0.284 3.71E−01 16.9 LYM137 12153.1 P 2.0334.60E−01 8.7 LYM105 12295.2 M 0.285 3.77E−01 17 LYM102 12222.3 P 2.2064.62E−01 18 LYM130 12331.3 M 0.28 4.04E−01 15.2 LYM17 11683.1 P 1.9364.85E−01 3.5 LYM148 12173.1 M 0.281 4.20E−01 15.5 LYM289 12491.1 P 2.1685.00E−01 15.9 LYM152 12376.1 M 0.281 4.24E−01 15.4 LYM10 11744.5 P 2.065.04E−01 10.1 LYM290 12501.3 M 0.279 4.35E−01 14.9 LYM1 11601.1 P 2.0755.18E−01 10.9 LYM57 12012.2 M 0.278 4.46E−01 14.4 LYM268 12483.4 P 2.0495.28E−01 9.5 LYM14 12052.4 M 0.275 4.87E−01 13.1 LYM17 11682.1 P 2.1545.33E−01 15.2 LYM137 12152.1 M 0.276 4.89E−01 13.3 LYM21 11672.4 P 2.0715.40E−01 10.7 LYM62 12022.1 M 0.274 5.01E−01 12.8 LYM111 12254.4 P 1.9295.68E−01 3.2 LYM137 12153.1 M 0.275 5.04E−01 13.1 LYM13 11771.9 P 1.9745.76E−01 5.5 LYM100 12134.1 M 0.273 5.19E−01 12.4 LYM268 12482.3 P 1.9745.94E−01 5.5 LYM26 11824.6 M 0.272 5.29E−01 11.9 LYM2 11693.3 P 1.9295.99E−01 3.1 LYM57 12012.6 M 0.271 5.53E−01 11.5 LYM290 12502.4 P 2.0256.17E−01 8.3 LYM53 11842.4 M 0.272 5.60E−01 12 LYM140 12261.4 P 1.9476.59E−01 4.1 LYM132 12271.4 M 0.27 5.68E−01 10.8 LYM268 12482.1 P 1.9696.73E−01 5.3 LYM68 11941.4 M 0.269 5.74E−01 10.5 LYM148 12172.1 P 2.0696.76E−01 10.6 LYM100 12131.3 M 0.268 5.89E−01 10.1 LYM10 11742.1 P 1.9996.93E−01 6.9 LYM152 12372.2 M 0.266 6.09E−01 9.6 LYM19 11752.2 P 1.9546.98E−01 4.5 LYM138 12562.1 M 0.266 6.32E−01 9.2 LYM143 12521.2 P 1.9117.08E−01 2.2 LYM43 11792.2 M 0.265 6.58E−01 8.9 LYM105 12294.2 P 2.0257.30E−01 8.3 LYM51 11894.2 M 0.262 6.76E−01 7.8 LYM111 12252.2 P 27.59E−01 6.9 LYM130 12334.1 M 0.26 6.96E−01 7 LYM100 12131.3 P 1.947.90E−01 3.7 LYM43 11793.2 M 0.262 7.03E−01 7.5 LYM153 12323.2 P 1.8937.92E−01 1.2 LYM134 12312.4 M 0.26 7.16E−01 7 LYM162 12233.2 P 1.9277.99E−01 3 LYM14 12051.4 M 0.26 7.20E−01 6.8 LYM143 12523.4 P 1.918.45E−01 2.1 LYM119 12461.4 M 0.259 7.29E−01 6.5 LYM2 11695.3 P 1.8858.49E−01 0.8 LYM132 12275.1 M 0.258 7.43E−01 6.1 LYM153 12321.2 P 1.9158.77E−01 2.4 LYM30 11912.7 M 0.257 7.63E−01 5.7 LYM9 11633.2 P 1.9138.81E−01 2.3 LYM254 12474.4 M 0.258 7.67E−01 6.2 LYM130 12331.3 P 1.8869.18E−01 0.9 LYM162 12231.3 M 0.257 7.67E−01 5.7 LYM132 12275.3 P 1.9089.31E−01 2 LYM143 12521.2 M 0.256 7.77E−01 5.3 LYM102 12222.6 P 1.8829.74E−01 0.6 LYM268 12482.1 M 0.257 7.87E−01 5.7 LYM290 12502.1 P 1.8719.99E−01 0 LYM100 12133.3 M 0.254 8.07E−01 4.6 CONTROL — P 1.87 — 0LYM69 11854.2 M 0.254 8.16E−01 4.4 LYM103 12713.5 A 95.446 6.40E−05 3.7LYM153 12321.2 M 0.254 8.20E−01 4.4 LYM20 11711.2 A 94.199 1.22E−03 2.3LYM30 11913.3 M 0.253 8.23E−01 4.2 LYM51 11891.1 A 93.981 1.89E−03 2.1LYM152 12371.2 M 0.252 8.64E−01 3.4 LYM110 12921.7 A 94.061 1.99E−03 2.2LYM67 11782.4 M 0.249 9.03E−01 2.3 LYM30 11913.3 A 93.936 2.18E−03 2.1LYM138 12564.1 M 0.247 9.36E−01 1.6 LYM31 11924.4 A 93.865 2.88E−03 2LYM152 12373.1 M 0.247 9.38E−01 1.6 LYM56 13111.5 A 93.843 2.90E−03 2LYM26 11824.5 M 0.247 9.39E−01 1.4 LYM82 12204.2 A 93.824 3.63E−03 1.9LYM51 11891.1 M 0.246 9.42E−01 1.3 LYM95 12121.2 A 94.294 3.66E−03 2.4LYM95 12124.4 M 0.245 9.64E−01 0.8 LYM30 11913.4 A 94.532 5.55E−03 2.7LYM268 12483.2 M 0.245 9.65E−01 0.9 LYM145 12951.9 A 93.612 6.11E−03 1.7LYM31 11922.3 M 0.245 9.70E−01 0.7 LYM95 12124.6 A 93.599 6.49E−03 1.7LYM172 12302.2 M 0.244 9.95E−01 0.1 LYM128 12641.3 A 93.573 6.95E−03 1.7CONTROL — M 0.243 — 0 LYM41 11834.2 A 93.777 7.60E−03 1.9 LYM111 12252.2N 0.365 8.67E−04 57.1 LYM43 11791.5 A 94.166 8.49E−03 2.3 LYM148 12174.1N 0.312 1.65E−02 34.3 LYM66 11954.4 A 93.658 1.06E−02 1.7 LYM69 11853.5N 0.295 5.60E−02 27 LYM14 12051.4 A 93.406 1.22E−02 1.5 LYM138 12561.1 N0.296 6.19E−02 27.2 LYM116 13202.12 A 93.753 1.48E−02 1.9 LYM119 12462.1N 0.29 8.42E−02 24.7 LYM271 12721.9 A 93.459 1.61E−02 1.5 LYM100 12131.2N 0.288 8.55E−02 23.7 LYM145 12954.8 A 93.311 1.71E−02 1.4 LYM14312524.2 N 0.286 9.40E−02 22.8 LYM41 11832.2 A 93.279 1.90E−02 1.3 LYM6811941.3 N 0.281 1.21E−01 21 LYM26 11821.2 A 93.294 2.17E−02 1.4 LYM11912461.1 N 0.295 1.24E−01 26.9 LYM53 11841.1 A 93.675 2.30E−02 1.8 LYM6711783.5 N 0.283 1.38E−01 21.6 LYM271 12724.7 A 93.539 2.83E−02 1.6LYM134 12314.2 N 0.277 1.56E−01 18.9 LYM232 13024.7 A 93.305 2.83E−021.4 LYM138 12561.3 N 0.278 1.57E−01 19.4 LYM271 12723.2 A 93.1623.14E−02 1.2 LYM31 11923.4 N 0.277 1.57E−01 19 LYM67 11782.6 A 94.3353.97E−02 2.5 LYM290 12502.4 N 0.277 1.64E−01 19 LYM110 12923.8 A 94.0144.09E−02 2.1 LYM57 12013.5 N 0.276 1.67E−01 18.7 LYM156 12961.7 A 93.7814.22E−02 1.9 LYM268 12482.3 N 0.276 1.68E−01 18.8 LYM88 12191.1 A 93.4384.39E−02 1.5 LYM53 11841.1 N 0.276 1.75E−01 18.7 LYM232 13024.6 A 93.094.49E−02 1.1 LYM62 12021.1 N 0.275 2.00E−01 18.4 LYM239 13044.8 A 93.0694.51E−02 1.1 LYM143 12524.7 N 0.28 2.15E−01 20.4 LYM239 13042.9 A 94.2425.48E−02 2.4 LYM30 11913.5 N 0.273 2.18E−01 17.4 LYM103 12712.8 A 93.6977.12E−02 1.8 LYM53 11844.2 N 0.272 2.53E−01 16.7 LYM67 11782.5 A 93.317.48E−02 1.4 LYM51 11893.4 N 0.272 2.62E−01 16.8 LYM26 11824.5 A 93.239.64E−02 1.3 LYM30 11912.6 N 0.268 2.72E−01 15.1 LYM24 12064.1 A 92.9771.09E−01 1 LYM68 11942.3 N 0.267 2.76E−01 15 LYM24 12061.4 A 93.5871.10E−01 1.7 LYM170 12453.2 N 0.264 3.05E−01 13.5 LYM26 11824.6 A 93.6261.16E−01 1.7 LYM68 11943.2 N 0.265 3.08E−01 14 LYM285 12733.9 A 93.4761.19E−01 1.6 LYM111 12254.3 N 0.271 3.36E−01 16.4 LYM99 12243.2 A 93.2271.26E−01 1.3 LYM137 12151.1 N 0.261 3.59E−01 12.4 LYM66 11952.2 A 92.7471.33E−01 0.8 LYM140 12264.1 N 0.26 3.88E−01 11.6 LYM82 12201.5 A 93.0061.35E−01 1 LYM152 12372.1 N 0.264 3.92E−01 13.5 LYM95 12124.4 A 93.5981.41E−01 1.7 LYM43 11791.5 N 0.258 4.06E−01 11 LYM26 11824.1 A 94.0621.54E−01 2.2 LYM137 12154.5 N 0.258 4.09E−01 11 LYM53 11844.2 A 92.9491.58E−01 1 LYM290 12502.2 N 0.258 4.41E−01 10.8 LYM238 12762.8 A 92.6611.75E−01 0.7 LYM111 12251.3 N 0.257 4.46E−01 10.7 LYM57 12013.3 A 93.0631.82E−01 1.1 LYM105 12295.2 N 0.256 4.60E−01 10.1 LYM125 12934.5 A94.064 1.92E−01 2.2 LYM111 12254.4 N 0.255 4.96E−01 9.7 LYM128 12641.5 A93.644 1.94E−01 1.7 LYM268 12481.1 N 0.253 5.27E−01 8.6 LYM51 11894.2 A92.955 1.98E−01 1 LYM51 11893.2 N 0.251 5.42E−01 8 LYM66 11955.2 A93.658 2.03E−01 1.7 LYM51 11891.1 N 0.251 5.54E−01 7.9 LYM238 12763.5 A93.475 2.13E−01 1.6 LYM68 11942.2 N 0.251 5.61E−01 8.1 LYM20 11712.2 A92.972 2.19E−01 1 LYM172 12301.2 N 0.25 5.79E−01 7.6 LYM145 12953.5 A93.925 2.34E−01 2 LYM137 12153.1 N 0.249 5.93E−01 7.3 LYM53 11843.2 A92.9 2.43E−01 0.9 LYM138 12562.1 N 0.249 6.03E−01 6.9 LYM125 12932.8 A97.238 2.56E−01 5.6 LYM43 11791.4 N 0.249 6.08E−01 6.9 LYM284 12883.5 A95.309 2.58E−01 3.5 LYM105 12294.3 N 0.248 6.13E−01 6.7 LYM41 11831.5 A93.347 2.68E−01 1.4 LYM148 12171.2 N 0.248 6.13E−01 6.7 LYM284 12884.7 A93.492 2.80E−01 1.6 LYM100 12131.3 N 0.248 6.13E−01 6.6 LYM125 12934.7 A92.535 2.81E−01 0.5 LYM62 12022.1 N 0.247 6.26E−01 6.4 LYM26 11824.3 A94.293 2.82E−01 2.4 LYM132 12276.1 N 0.249 6.26E−01 6.9 LYM277 13104.9 A94.232 3.03E−01 2.4 LYM130 12331.3 N 0.247 6.36E−01 6.1 LYM156 12963.4 A93.322 3.23E−01 1.4 LYM26 11824.6 N 0.248 6.42E−01 6.5 LYM277 13101.1 A93.457 3.32E−01 1.5 LYM14 12052.4 N 0.245 6.80E−01 5.5 LYM277 13105.7 A93.165 3.34E−01 1.2 LYM152 12376.1 N 0.246 6.82E−01 5.6 LYM88 12194.2 A92.773 3.50E−01 0.8 LYM43 11792.2 N 0.246 6.97E−01 5.7 LYM30 11912.7 A93.371 3.68E−01 1.4 LYM100 12134.1 N 0.245 7.03E−01 5.3 LYM103 12712.5 A94.013 3.80E−01 2.1 LYM57 12012.2 N 0.244 7.15E−01 4.8 LYM116 13204.4 A92.411 4.06E−01 0.4 LYM105 12297.1 N 0.243 7.31E−01 4.7 LYM99 12244.1 A92.873 4.11E−01 0.9 LYM137 12152.1 N 0.242 7.68E−01 3.9 LYM57 12013.5 A92.867 4.13E−01 0.9 LYM152 12372.2 N 0.242 7.69E−01 3.9 LYM128 12641.1 A92.436 4.13E−01 0.4 LYM100 12133.3 N 0.241 7.86E−01 3.6 LYM110 12924.5 A93.592 4.13E−01 1.7 LYM119 12462.2 N 0.241 7.88E−01 3.7 LYM66 11953.6 A93.538 4.18E−01 1.6 LYM24 12061.2 N 0.241 7.97E−01 3.6 LYM57 12012.2 A92.705 4.22E−01 0.7 LYM143 12521.2 N 0.24 8.16E−01 3.1 LYM145 12952.9 A92.482 4.55E−01 0.5 LYM148 12173.1 N 0.24 8.22E−01 3 LYM99 12241.1 A93.281 4.58E−01 1.3 LYM69 11854.2 N 0.239 8.47E−01 2.5 LYM156 12961.9 A93.723 4.82E−01 1.8 LYM14 12051.4 N 0.237 8.82E−01 2 LYM56 13112.7 A93.781 4.85E−01 1.9 LYM132 12271.4 N 0.237 8.82E−01 2 LYM82 12201.1 A92.948 5.15E−01 1 LYM290 12501.3 N 0.237 8.83E−01 2 LYM116 13202.7 A92.951 5.22E−01 1 LYM268 12482.1 N 0.238 8.83E−01 2.3 LYM239 13041.7 A92.482 5.31E−01 0.5 LYM152 12373.1 N 0.237 9.00E−01 1.9 LYM284 12884.6 A92.958 5.74E−01 1 LYM254 12474.4 N 0.237 9.03E−01 1.9 LYM56 13112.5 A93.518 5.79E−01 1.6 LYM68 11941.4 N 0.236 9.24E−01 1.3 LYM156 12963.3 A92.931 5.88E−01 1 LYM130 12334.1 N 0.235 9.24E−01 1.2 LYM51 11893.4 A92.963 5.94E−01 1 LYM111 12251.1 N 0.235 9.41E−01 1 LYM121 13211.8 A92.858 6.05E−01 0.9 LYM14 12052.5 N 0.235 9.44E−01 0.9 LYM110 12923.5 A92.576 6.26E−01 0.6 LYM66 11954.4 N 0.235 9.46E−01 1.1 LYM67 11782.4 A92.533 6.33E−01 0.5 LYM140 12261.1 N 0.234 9.57E−01 0.8 LYM12 11871.1 A92.319 6.34E−01 0.3 LYM152 12371.2 N 0.234 9.76E−01 0.4 LYM103 12713.7 A93.46 6.35E−01 1.5 CONTROL — N 0.233 — 0 LYM62 12022.4 A 93.315 6.56E−011.4 LYM134 12314.2 O 2.877 1.57E−04 44.9 LYM43 11793.2 A 92.84 6.72E−010.9 LYM268 12482.3 O 2.827 2.54E−04 42.3 LYM69 11852.4 A 92.347 6.74E−010.3 LYM138 12561.1 O 3.132 7.56E−04 57.7 LYM31 11923.1 A 93.048 6.91E−011.1 LYM43 11791.5 O 2.978 3.01E−03 49.9 LYM99 12244.2 A 92.212 7.08E−010.2 LYM100 12131.2 O 3.097 5.61E−03 55.9 LYM95 12121.4 A 92.376 7.27E−010.4 LYM170 12453.2 O 2.589 6.69E−03 30.3 LYM43 11792.2 A 92.62 7.34E−010.6 LYM140 12264.1 O 2.557 7.02E−03 28.7 LYM14 12052.4 A 92.727 7.41E−010.7 LYM57 12013.5 O 2.672 1.45E−02 34.6 LYM66 11953.1 A 92.666 7.44E−010.7 LYM68 11942.3 O 2.737 1.48E−02 37.8 LYM12 11872.1 A 92.724 7.81E−010.7 LYM143 12524.2 O 2.755 1.94E−02 38.7 LYM238 12764.8 A 92.2367.83E−01 0.2 LYM148 12174.1 O 3.67 2.35E−02 84.8 LYM116 13201.8 A 92.4847.84E−01 0.5 LYM31 11923.4 O 2.751 2.44E−02 38.5 LYM82 12203.3 A 92.1758.22E−01 0.1 LYM130 12331.3 O 2.363 2.49E−02 19 LYM238 12761.6 A 92.2228.23E−01 0.2 LYM69 11853.5 O 2.572 4.76E−02 29.5 LYM67 11781.5 A 92.6228.43E−01 0.6 LYM290 12502.4 O 2.809 5.25E−02 41.4 LYM232 13024.4 A92.931 8.45E−01 1 LYM137 12151.1 O 2.72 5.81E−02 37 LYM67 11783.5 A92.182 8.54E−01 0.1 LYM57 12012.2 O 2.266 6.86E−02 14.1 LYM88 12193.1 A92.108 8.99E−01 0.1 LYM51 11893.2 O 2.359 7.59E−02 18.8 LYM20 11716.3 A92.257 9.05E−01 0.2 LYM53 11841.1 O 2.817 7.71E−02 41.9 LYM121 13214.3 A92.309 9.05E−01 0.3 LYM14 12052.4 O 2.264 8.31E−02 14 LYM232 13022.1 A92.236 9.28E−01 0.2 LYM132 12276.1 O 2.274 9.43E−02 14.5 LYM31 11921.3 A92.086 9.31E−01 0 LYM138 12561.3 O 2.884 9.53E−02 45.2 LYM271 12721.8 A92.21 9.39E−01 0.2 LYM148 12171.2 O 2.638 1.02E−01 32.8 LYM99 12243.1 A92.142 9.40E−01 0.1 LYM68 11941.4 O 2.223 1.03E−01 11.9 LYM88 12193.5 A92.179 9.49E−01 0.1 LYM119 12462.1 O 3.201 1.06E−01 61.2 LYM121 13211.6A 92.125 9.70E−01 0.1 LYM119 12462.2 O 2.481 1.06E−01 24.9 LYM69 11853.5A 92.063 9.73E−01 0 LYM137 12152.1 O 2.226 1.08E−01 12.1 LYM284 12882.5A 92.091 9.89E−01 0 LYM68 11941.3 O 2.673 1.27E−01 34.6 LYM125 12931.5 A92.065 9.94E−01 0 LYM43 11791.4 O 2.52 1.37E−01 26.9 CONTROL — A 92.048— 0 LYM111 12252.2 O 4.449 1.69E−01 124 LYM95 12124.4 B 0.391 1.15E−018.6 LYM130 12334.1 O 2.179 1.70E−01 9.7 LYM69 11852.2 B 0.388 1.69E−017.7 LYM105 12294.3 O 2.35 1.77E−01 18.3 LYM51 11891.1 B 0.421 3.86E−0116.9 LYM30 11913.5 O 2.495 2.05E−01 25.6 LYM66 11953.6 B 0.376 4.19E−014.3 LYM268 12481.1 O 2.311 2.11E−01 16.4 LYM67 11782.6 B 0.408 4.83E−0113.3 LYM148 12173.1 O 2.29 2.22E−01 15.3 LYM66 11954.4 B 0.372 5.30E−013.2 LYM100 12131.3 O 2.168 2.24E−01 9.2 LYM99 12244.1 B 0.369 6.38E−012.4 LYM68 11943.2 O 2.559 2.28E−01 28.9 LYM67 11782.4 B 0.374 6.79E−013.9 LYM152 12372.2 O 2.215 2.44E−01 11.5 LYM99 12243.1 B 0.365 8.06E−011.3 LYM137 12154.5 O 2.426 2.44E−01 22.1 LYM43 11793.2 B 0.374 8.36E−013.9 LYM105 12295.2 O 2.33 2.62E−01 17.3 LYM31 11924.4 B 0.369 9.06E−012.5 LYM130 12332.2 O 2.424 2.81E−01 22.1 LYM57 12013.3 B 0.363 9.80E−010.8 LYM172 12301.2 O 2.425 2.87E−01 22.1 CONTROL — B 0.36 — 0 LYM29012501.3 O 2.272 2.90E−01 14.4 LYM95 12124.4 C 4.281 2.01E−03 22.8 LYM6811942.2 O 2.355 3.00E−01 18.6 LYM66 11953.6 C 4.238 4.68E−03 21.6 LYM6212022.1 O 2.266 3.17E−01 14.1 LYM67 11782.4 C 4.006 2.07E−02 14.9 LYM5712012.6 O 2.232 3.21E−01 12.4 LYM99 12244.1 C 4.006 2.94E−02 14.9 LYM11112254.4 O 2.464 3.28E−01 24 LYM99 12243.2 C 3.969 3.28E−02 13.9 LYM11112251.3 O 2.404 3.30E−01 21 LYM66 11954.4 C 3.913 3.91E−02 12.3 LYM3011912.6 O 2.563 3.48E−01 29 LYM69 11852.2 C 3.931 5.24E−02 12.8 LYM5111894.2 O 2.14 3.52E−01 7.8 LYM67 11782.5 C 3.875 5.34E−02 11.2 LYM5311844.2 O 2.521 3.61E−01 26.9 LYM82 12203.3 C 3.813 9.88E−02 9.4 LYM13712153.1 O 2.252 3.67E−01 13.4 LYM88 12194.2 C 3.794 1.08E−01 8.8 LYM6212021.1 O 2.472 3.77E−01 24.5 LYM51 11891.1 C 3.813 1.95E−01 9.4 LYM13212271.4 O 2.221 4.01E−01 11.8 LYM53 11841.1 C 3.744 2.04E−01 7.4 LYM5111893.4 O 2.822 4.03E−01 42.1 LYM43 11791.5 C 3.681 2.86E−01 5.6 LYM11912461.1 O 3.049 4.11E−01 53.5 LYM99 12241.1 C 3.65 3.67E−01 4.7 LYM15212376.1 O 2.314 4.14E−01 16.5 LYM67 11782.6 C 4.25 3.83E−01 21.9 LYM10012134.1 O 2.217 4.18E−01 11.6 LYM53 11841.2 C 3.631 4.57E−01 4.2 LYM11112254.3 O 2.789 4.58E−01 40.4 LYM82 12201.5 C 3.794 4.71E−01 8.8 LYM10012133.3 O 2.087 4.87E−01 5.1 LYM43 11793.2 C 3.794 5.39E−01 8.8 LYM14312524.7 O 2.93 4.89E−01 47.6 LYM67 11783.5 C 3.594 6.03E−01 3.1 LYM15212372.1 O 2.572 4.90E−01 29.5 LYM53 11842.4 C 3.575 6.17E−01 2.6 LYM14312521.2 O 2.073 5.09E−01 4.4 LYM99 12243.1 C 3.588 6.17E−01 2.9 LYM1412051.4 O 2.148 5.20E−01 8.2 LYM82 12201.1 C 3.569 6.50E−01 2.4 LYM29012502.2 O 2.383 5.23E−01 20 LYM51 11893.4 C 3.59 6.68E−01 3 LYM6711783.5 O 2.307 5.53E−01 16.2 LYM88 12193.1 C 3.694 7.08E−01 6 LYM2611824.6 O 2.205 5.59E−01 11 LYM88 12193.5 C 3.681 7.16E−01 5.6 LYM13412312.4 O 2.116 5.72E−01 6.5 LYM69 11854.2 C 3.556 7.53E−01 2 LYM13212275.1 O 2.067 6.20E−01 4.1 LYM66 11955.2 C 3.625 8.66E−01 4 LYM5311842.4 O 2.289 6.36E−01 15.3 LYM51 11892.1 C 3.5 9.37E−01 0.4 LYM4311792.2 O 2.174 6.56E−01 9.4 CONTROL — C 3.485 — 0 LYM119 12461.4 O2.115 6.64E−01 6.5 LYM116 13202.12 D 0.379 1.40E−05 41.9 LYM30 11912.7 O2.115 6.90E−01 6.5 LYM67 11782.6 D 0.337 4.39E−04 26.2 LYM138 12562.1 O2.128 7.14E−01 7.1 LYM128 12641.5 D 0.364 8.83E−04 36.4 LYM43 11793.2 O2.162 7.20E−01 8.9 LYM20 11711.2 D 0.363 8.90E−04 36.1 LYM30 11913.3 O2.064 7.61E−01 3.9 LYM238 12764.8 D 0.334 7.05E−03 25.3 LYM162 12231.3 O2.096 7.65E−01 5.6 LYM88 12193.1 D 0.298 2.70E−02 11.8 LYM95 12124.4 O2.032 7.69E−01 2.3 LYM12 11871.3 D 0.298 3.76E−02 11.8 LYM67 11782.4 O2.035 8.22E−01 2.5 LYM116 13202.7 D 0.321 3.92E−02 20.2 LYM153 12321.2 O2.051 8.30E−01 3.3 LYM239 13042.9 D 0.33 5.21E−02 23.8 LYM152 12371.2 O2.071 8.45E−01 4.3 LYM53 11841.1 D 0.303 7.50E−02 13.5 LYM254 12474.4 O2.107 8.58E−01 6.1 LYM26 11824.3 D 0.312 8.07E−02 17 LYM268 12482.1 O2.111 8.72E−01 6.3 LYM99 12243.1 D 0.348 8.18E−02 30.4 LYM69 11854.2 O2.006 9.07E−01 1 LYM31 11923.4 D 0.289 1.00E−01 8.3 LYM31 11922.3 O2.008 9.14E−01 1.1 LYM31 11924.4 D 0.297 1.21E−01 11.4 LYM152 12373.1 O2.03 9.27E−01 2.2 LYM66 11955.2 D 0.289 1.36E−01 8.5 LYM69 11852.4 O2.006 9.29E−01 1 LYM53 11843.2 D 0.287 1.41E−01 7.7 LYM26 11824.5 O1.995 9.47E−01 0.5 LYM26 11824.6 D 0.327 1.42E−01 22.4 LYM268 12483.2 O2.007 9.62E−01 1.1 LYM285 12733.9 D 0.38 1.57E−01 42.3 CONTROL — O 1.986— 0 LYM20 11716.5 D 0.292 1.84E−01 9.5 LYM68 11941.3 P 2.991 4.57E−0424.7 LYM103 12713.5 D 0.346 1.85E−01 29.6 LYM134 12314.2 P 2.9745.82E−04 24 LYM24 12061.4 D 0.327 1.93E−01 22.7 LYM148 12174.1 P 3.4619.68E−04 44.3 LYM14 12051.4 D 0.307 1.94E−01 15 LYM57 12013.5 P 2.9011.36E−03 20.9 LYM26 11824.1 D 0.338 1.97E−01 26.8 LYM268 12482.3 P 2.9452.74E−03 22.8 LYM238 12763.7 D 0.283 1.97E−01 6.1 LYM31 11923.4 P 2.9442.83E−03 22.7 LYM66 11954.4 D 0.322 2.07E−01 20.7 LYM140 12264.1 P 2.7915.07E−03 16.4 LYM12 11872.1 D 0.404 2.11E−01 51.6 LYM100 12131.2 P 3.0856.47E−03 28.6 LYM99 12244.2 D 0.283 2.45E−01 6.2 LYM130 12331.3 P 2.7121.54E−02 13 LYM12 11871.1 D 0.334 2.71E−01 25.1 LYM148 12171.2 P 2.7481.78E−02 14.5 LYM128 12641.3 D 0.325 2.98E−01 21.7 LYM51 11893.2 P 2.6991.88E−02 12.5 LYM239 13044.8 D 0.302 3.23E−01 13 LYM138 12561.1 P 3.1542.51E−02 31.5 LYM232 13024.6 D 0.295 3.63E−01 10.7 LYM69 11853.5 P 2.9682.79E−02 23.7 LYM103 12712.8 D 0.305 3.64E−01 14.3 LYM290 12502.4 P2.886 2.85E−02 20.3 LYM95 12121.2 D 0.332 3.79E−01 24.5 LYM170 12453.2 P2.703 2.98E−02 12.7 LYM95 12124.4 D 0.289 4.16E−01 8.4 LYM143 12524.2 P2.943 3.25E−02 22.7 LYM69 11852.2 D 0.281 4.94E−01 5.2 LYM68 11942.3 P2.866 3.61E−02 19.5 LYM156 12963.1 D 0.29 5.11E−01 8.6 LYM53 11841.1 P2.971 4.36E−02 23.9 LYM82 12201.1 D 0.275 5.11E−01 3.1 LYM57 12012.2 P2.629 5.16E−02 9.6 LYM67 11782.4 D 0.288 5.17E−01 8.1 LYM119 12462.1 P3.134 6.34E−02 30.7 LYM30 11912.6 D 0.29 5.57E−01 8.6 LYM137 12152.1 P2.596 8.59E−02 8.2 LYM24 12064.1 D 0.3 5.74E−01 12.5 LYM62 12022.1 P2.63 8.66E−02 9.6 LYM26 11824.5 D 0.309 6.01E−01 15.9 LYM138 12561.3 P3.014 8.88E−02 25.6 LYM232 13024.7 D 0.33 6.01E−01 23.6 LYM137 12151.1 P2.926 9.19E−02 22 LYM30 11912.7 D 0.277 6.08E−01 3.7 LYM137 12153.1 P2.702 9.26E−02 12.6 LYM26 11821.2 D 0.286 6.37E−01 7.3 LYM130 12332.2 P2.673 1.06E−01 11.4 LYM103 12711.8 D 0.273 6.74E−01 2.5 LYM43 11791.5 P2.949 1.06E−01 22.9 LYM103 12712.5 D 0.273 6.81E−01 2.3 LYM43 11791.4 P2.739 1.20E−01 14.2 LYM116 13204.4 D 0.31 7.10E−01 16.3 LYM111 12252.2 P3.85 1.23E−01 60.5 LYM62 12023.2 D 0.273 7.33E−01 2.2 LYM105 12295.2 P2.705 1.58E−01 12.8 LYM128 12641.1 D 0.279 7.45E−01 4.4 LYM100 12131.3 P2.551 1.66E−01 6.3 LYM57 12012.2 D 0.271 7.62E−01 1.4 LYM30 11913.5 P2.823 1.67E−01 17.7 LYM66 11953.6 D 0.27 7.80E−01 1.3 LYM137 12154.5 P2.674 1.74E−01 11.5 LYM31 11921.3 D 0.269 8.84E−01 1 LYM100 12134.1 P2.625 1.75E−01 9.4 LYM30 11913.5 D 0.273 8.96E−01 2.4 LYM119 12462.2 P2.683 1.81E−01 11.8 LYM156 12961.9 D 0.268 9.20E−01 0.6 LYM130 12334.1 P2.543 2.00E−01 6 LYM145 12951.9 D 0.267 9.76E−01 0.2 LYM30 11912.6 P2.794 2.04E−01 16.5 CONTROL — D 0.267 — 0 LYM68 11941.4 P 2.535 2.13E−015.7 LYM26 11824.3 E 8.813 2.28E−03 8.7 LYM105 12294.3 P 2.685 2.22E−0111.9 LYM82 12201.1 E 9.125 4.62E−03 12.5 LYM68 11943.2 P 2.853 2.25E−0118.9 LYM285 12733.9 E 9 7.67E−03 11 LYM268 12481.1 P 2.672 2.31E−01 11.4LYM24 12064.1 E 8.625 9.72E−03 6.4 LYM111 12251.3 P 2.689 2.51E−01 12.1LYM53 11841.1 E 8.875 1.34E−02 9.4 LYM14 12052.4 P 2.609 2.63E−01 8.8LYM12 11872.1 E 8.563 2.18E−02 5.6 LYM134 12312.4 P 2.518 2.68E−01 4.9LYM95 12121.2 E 9.313 2.37E−02 14.8 LYM111 12254.4 P 2.753 2.72E−01 14.7LYM31 11923.4 E 8.75 2.50E−02 7.9 LYM57 12012.6 P 2.524 2.86E−01 5.2LYM43 11791.4 E 8.75 2.50E−02 7.9 LYM62 12021.1 P 2.827 2.91E−01 17.8LYM99 12243.2 E 8.75 2.50E−02 7.9 LYM152 12372.2 P 2.623 3.12E−01 9.3LYM128 12641.5 E 9.188 3.04E−02 13.3 LYM143 12521.2 P 2.539 3.29E−01 5.8LYM67 11782.6 E 8.625 4.97E−02 6.4 LYM53 11844.2 P 2.851 3.42E−01 18.8LYM99 12244.2 E 8.625 4.97E−02 6.4 LYM172 12301.2 P 2.688 3.44E−01 12.1LYM66 11954.4 E 8.938 5.42E−02 10.2 LYM67 11783.5 P 2.698 3.48E−01 12.5LYM99 12243.1 E 9.25 7.13E−02 14.1 LYM51 11893.4 P 2.942 3.50E−01 22.6LYM30 11913.4 E 8.438 7.36E−02 4 LYM132 12271.4 P 2.569 3.58E−01 7.1LYM66 11953.6 E 8.438 7.36E−02 4 LYM290 12502.2 P 2.694 3.87E−01 12.3LYM95 12124.4 E 8.438 7.36E−02 4 LYM119 12461.1 P 3.083 3.95E−01 28.5LYM128 12641.3 E 8.813 7.63E−02 8.7 LYM68 11942.2 P 2.673 3.96E−01 11.4LYM103 12713.5 E 8.5 1.05E−01 4.8 LYM152 12376.1 P 2.632 4.09E−01 9.7LYM26 11824.6 E 8.5 1.05E−01 4.8 LYM138 12562.1 P 2.59 4.09E−01 8 LYM2412061.4 E 9 1.06E−01 11 LYM290 12501.3 P 2.571 4.21E−01 7.2 LYM23812764.8 E 8.688 1.12E−01 7.1 LYM51 11891.1 P 2.501 4.32E−01 4.2 LYM14512951.9 E 8.375 1.13E−01 3.3 LYM111 12254.3 P 2.964 4.42E−01 23.6 LYM8812194.2 E 8.563 1.73E−01 5.6 LYM143 12524.7 P 2.928 4.42E−01 22 LYM2611824.1 E 8.75 1.74E−01 7.9 LYM95 12124.4 P 2.485 4.88E−01 3.6 LYM2011711.2 E 8.938 1.81E−01 10.2 LYM148 12173.1 P 2.551 4.89E−01 6.3 LYM1412051.4 E 8.813 2.22E−01 8.7 LYM152 12372.1 P 2.816 5.25E−01 17.4 LYM11613202.12 E 8.375 2.33E−01 3.3 LYM100 12133.3 P 2.501 5.25E−01 4.3 LYM9912241.1 E 8.375 2.33E−01 3.3 LYM26 11824.6 P 2.619 5.33E−01 9.2 LYM3011912.6 E 8.313 2.38E−01 2.5 LYM111 12251.1 P 2.463 5.41E−01 2.7 LYM23913042.9 E 8.438 2.80E−01 4 LYM51 11894.2 P 2.462 5.54E−01 2.6 LYM6911852.2 E 8.938 2.86E−01 10.2 LYM14 12051.4 P 2.534 5.68E−01 5.6 LYM12812641.1 E 8.5 3.24E−01 4.8 LYM105 12297.1 P 2.475 5.86E−01 3.1 LYM5712012.2 E 8.5 3.24E−01 4.8 LYM132 12276.1 P 2.532 5.96E−01 5.5 LYM3111921.3 E 8.554 3.53E−01 5.5 LYM43 11792.2 P 2.564 6.02E−01 6.9 LYM6611955.2 E 8.938 3.68E−01 10.2 LYM30 11913.3 P 2.456 6.49E−01 2.4 LYM8812193.1 E 8.625 3.80E−01 6.4 LYM162 12231.3 P 2.496 6.50E−01 4.1 LYM6611952.2 E 8.375 4.66E−01 3.3 LYM30 11913.4 P 2.472 6.77E−01 3 LYM23213024.7 E 8.313 4.68E−01 2.5 LYM119 12461.4 P 2.515 7.10E−01 4.9 LYM9912244.1 E 8.438 4.71E−01 4 LYM152 12371.2 P 2.508 7.20E−01 4.5 LYM3111924.4 E 8.563 4.80E−01 5.6 LYM53 11842.4 P 2.589 7.25E−01 7.9 LYM5111891.1 E 8.25 5.02E−01 1.7 LYM43 11793.2 P 2.535 7.25E−01 5.7 LYM5311842.4 E 8.25 5.02E−01 1.7 LYM30 11912.7 P 2.442 7.59E−01 1.8 LYM6212023.5 E 8.25 5.02E−01 1.7 LYM152 12373.1 P 2.503 7.68E−01 4.3 LYM6212023.2 E 8.688 5.52E−01 7.1 LYM26 11824.5 P 2.428 7.79E−01 1.2 LYM1211873.4 E 8.438 5.87E−01 4 LYM132 12275.1 P 2.424 8.07E−01 1.1 LYM1211871.3 E 8.188 6.37E−01 1 LYM69 11852.4 P 2.439 8.44E−01 1.7 LYM5311843.2 E 8.188 6.37E−01 1 LYM31 11922.3 P 2.425 8.59E−01 1.1 LYM6711782.4 E 8.438 6.63E−01 4 LYM254 12474.4 P 2.487 8.63E−01 3.7 LYM4311793.2 E 8.438 7.17E−01 4 LYM268 12482.1 P 2.471 8.81E−01 3 LYM2611821.2 E 8.313 7.24E−01 2.5 LYM66 11954.4 P 2.478 8.96E−01 3.3 LYM1211871.1 E 8.5 7.33E−01 4.8 LYM153 12321.2 P 2.423 9.16E−01 1 LYM23913044.8 E 8.188 7.69E−01 1 LYM290 12502.1 P 2.411 9.36E−01 0.5 LYM28512734.9 E 8.313 7.80E−01 2.5 LYM62 12022.2 P 2.412 9.44E−01 0.5 LYM4311791.5 E 8.125 9.18E−01 0.2 LYM67 11782.4 P 2.406 9.49E−01 0.3 LYM11613204.4 E 8.188 9.28E−01 1 LYM162 12234.3 P 2.4 9.95E−01 0 LYM30 11913.5E 8.188 9.28E−01 1 CONTROL — P 2.399 — 0 LYM232 13024.6 E 8.125 9.39E−010.2 LYM30 11912.7 E 8.188 9.39E−01 1 LYM67 11782.5 E 8.125 9.62E−01 0.2LYM26 11824.5 E 8.125 9.89E−01 0.2 CONTROL — E 8.109 — 0 Table 32.Results of the greenhouse experiments. Provided are the measured valuesof each tested parameter [parameters (ID.) A-P according to theparameters described in Table 31 above] in plants expressing theindicated polynucleotides. “Ev” = event; “P” = P-value; “Mean” = theaverage of measured parameter across replicates. % incr. vs. cont. =percentage of increase versus control (as compared to control).

Example 11 Improved Transgenic Plant Performance—Tissue Culture Assays

To analyze the effect of expression of the isolated polynucleotides inplants, plants performance was tested in tissue culture.

Plant growth under favorable conditions in tissue culture using T1 or T2plants—The experiments used either T2 seeds (T2 experiments hereinbelow) or T1 seeds (T1 experiments herein below). Surface sterilized T1or T2 seeds were sown in basal media [50% Murashige-Skoog medium (MS)supplemented with 0.8% plant agar as solidifying agent] in the presenceof Kanamycin (for selecting only transgenic plants). After sowing,plates were transferred for 2-3 days for stratification at 4° C. andthen grown at 25° C. under 12-hour light 12-hour dark daily cycles for 7to 10 days. At this time point, at T2 experiments seedlings randomlychosen were carefully transferred to plates containing 0.5 MS media.Each plate contained 5 seedlings of the same transgenic event, and 3-4different plates (replicates) for each event. For each polynucleotide ofthe invention at least four independent transformation events wereanalyzed from each construct. Plants expressing the polynucleotides ofthe invention were compared to the average measurement of the controlplants (empty vector or GUS reporter gene under the same promoter) usedin the same experiment. Alternatively, at T1 experiments seedlingsrandomly chosen were carefully transferred to plates containing 0.5 MSmedia. Each plate contained 5 T1 seedlings representing 5 independenttransgenic events, and 3-4 different plates (total of 15-20 events).Plants expressing the polynucleotides of the invention were compared tothe average measurement of the control plants (empty vector or GUSreporter gene under the same promoter) used in the same experiment.

Plant growth under low nitrogen conditions in Tissue culture using T2plants—Surface sterilized seeds were sown in basal media [50%Murashige-Skoog medium (MS) supplemented with 0.8% plant agar assolidifying agent] in the presence of Kanamycin (used as a selectingagent). After sowing, plates were transferred for 2-3 days forstratification at 4° C. and then grown at 25° C. under 12-hour light12-hour dark daily cycles for 7 to 10 days. At this time point,seedlings randomly chosen were carefully transferred to platescontaining ½ MS media (15 mM N) for the normal nitrogen concentrationtreatment and 0.75 mM nitrogen for the low nitrogen concentrationtreatments. Each plate contained 5 seedlings of the same transgenicevent, and 3-4 different plates (replicates) for each event. For eachpolynucleotide of the invention at least four independent transformationevents were analyzed from each construct. Plants expressing thepolynucleotides of the invention were compared to the averagemeasurement of the control plants (empty vector or GUS reporter geneunder the same promoter) used in the same experiment.

For both experiments the same plant parameters were being measured andbeing described below:

Digital imaging—A laboratory image acquisition system, which consists ofa digital reflex camera (Canon EOS 300D) attached with a 55 mm focallength lens (Canon EF-S series), mounted on a reproduction device(Kaiser RS), which included 4 light units (4×150 Watts light bulb) andlocated in a darkroom, is used for capturing images of plantlets sawn inagar plates.

The image capturing process is repeated every 4 days starting at day 1till day 10. An image analysis system was used, which consists of apersonal desktop computer (Intel P4 3.0 GHz processor) and a publicdomain program—ImageJ 1.39 [Java based image processing program whichwas developed at the U.S. National Institutes of Health and freelyavailable on the internet at Hypertext Transfer Protocol://rsbweb (dot)nih (dot) gov/]. Images were captured in resolution of 10 Mega Pixels(3888×2592 pixels) and stored in a low compression JPEG (JointPhotographic Experts Group standard) format. Next, analyzed data wassaved to text files and processed using the JMP statistical analysissoftware (SAS institute).

Seedling analysis—Using the digital analysis seedling data wascalculated, including leaf area, root coverage and root length.

The relative growth rate for the various seedling parameters wascalculated according to the following formulas XVII, VII and XVIII.Relative growth rate of leaf area=Regression coefficient of leaf areaalong time course.  Formula XVIIRelative growth rate of root coverage=Regression coefficient of rootcoverage along time course.  Formula VII (above)Relative growth rate of root length=Regression coefficient of rootlength along time course.  Formula XVIII:

At the end of the experiment, plantlets were removed from the media andweighed for the determination of plant fresh weight. Plantlets were thendried for 24 hours at 60° C., and weighed again to measure plant dryweight for later statistical analysis. Growth rate is determined bycomparing the leaf area coverage, root coverage and root length, betweeneach couple of sequential photographs, and results were used to resolvethe effect of the gene introduced on plant vigor under optimalconditions. Similarly, the effect of the gene introduced on biomassaccumulation, under optimal conditions, is determined by comparing theplants' fresh and dry weight to that of control plants (containing anempty vector or the GUS reporter gene under the same promoter). Fromevery construct created, 3-5 independent transformation events wereexamined in replicates.

Statistical analyses—To identify genes conferring significantly improvedplant vigor or enlarged root architecture, the results obtained from thetransgenic plants were compared to those obtained from control plants.To identify outperforming genes and constructs, results from theindependent transformation events tested were analyzed separately (T2experiments) or as average of events (T1 experiments). To evaluate theeffect of a gene event (T2 experiments) or gene (T1 experiment) over acontrol the data is analyzed by Student's t-test and the p value iscalculated. Results were considered significant if p≦0.1. The JMPstatistics software package was used (Version 5.2.1, SAS Institute Inc.,Cary, N.C., USA).

Tables 33, 35 and 37 specify the parameters measured in plants in thetissue culture assays (T2 plants, T1 plants and low nitrogen T2 plants).

Experimental Results

Plans expressing the polynucleotides of the invention were assayed for anumber of commercially desired traits. In cases where a certain eventappears more than once, the event was tested in several independentexperiments.

TABLE 33 Measured parameters at the tissue culture assay (T2 experiment)for transformed agriculture improving trait genes Tested Parameters IDDry Weight (gr) A Fresh Weight (gr) B RGR Of Root Coverage C RootsCoverage TP3 (cm²) D RGR Of Roots Length E Roots Length TP3 (cm) F LeafArea TP3 (cm) G RGR Of Leaf Area H Table 33: Provided are theidentification (ID) letters of each of the Tested Parameters. TP3—TimePoint 3; RGR—Relative Growth Rate.

TABLE 34 Results obtained in a T2 experiment at the tissue culture assay% % incr. incr. Gene P vs. Gene P vs. name Event ID Mean value cont.name Event ID Mean value cont. LYM37 11801.2 A 0.007 4.96E−04 60.3 LYM111602.6 H 0.104 0.00E+00 124 LYM34 11902.2 A 0.006 2.28E−02 33.5 LYM13212275.3 H 0.085 0.00E+00 82.4 LYM34 11904.3 A 0.006 7.24E−02 27.6 LYM17812164.3 H 0.106 0.00E+00 128.4 LYM34 11901.1 A 0.005 8.11E−02 15.8LYM132 12271.4 H 0.075 1.00E−06 61.2 LYM35 11813.5 A 0.005 8.90E−02 14.7LYM1 11601.1 H 0.074 2.00E−06 60.1 CONTROL — A 0.005 — 0 LYM178 12163.3H 0.093 2.00E−06 100.8 LYM34 11904.3 B 0.119 8.41E−02 27.7 LYM13212276.1 H 0.086 6.00E−06 84.4 LYM35 11813.5 B 0.109 9.32E−02 16.8 LYM13412314.2 H 0.075 3.10E−05 61.1 CONTROL — B 0.093 — 0 LYM6 11736.1 H 0.0775.10E−05 66 LYM37 11801.1 C 0.697 1.40E−05 69.9 LYM268 12482.1 H 0.0726.60E−05 54.4 LYM12 11874.1 C 0.59 3.88E−02 43.9 LYM129 12573.5 H 0.0781.22E−04 68.6 LYM35 11813.5 C 0.518 7.38E−02 26.2 LYM1 11603.2 H 0.0665.10E−04 42.6 LYM37 11803.2 C 0.527 8.20E−02 28.3 LYM268 12483.2 H 0.0725.20E−04 54.1 LYM34 11902.2 C 0.505 9.84E−02 23.1 LYM134 12313.2 H 0.0988.99E−04 111.5 CONTROL — C 0.41 — 0 LYM178 12164.2 H 0.064 1.35E−03 37.5LYM37 11801.1 D 6.178 1.90E−05 69.5 LYM5 12432.1 H 0.072 1.67E−03 54.4LYM41 11831.5 D 4.331 7.99E−02 18.8 LYM268 12483.4 H 0.07 3.94E−03 50.7CONTROL — D 3.645 — 0 LYM268 12482.3 H 0.064 5.44E−03 36.9 LYM37 11801.1E 0.5 9.40E−05 48.1 LYM5 12435.1 H 0.067 9.04E−03 44.9 LYM34 11902.4 E0.434 4.61E−03 28.8 LYM6 11735.1 H 0.064 1.69E−02 37.6 LYM12 11871.1 E0.421 1.67E−02 24.7 LYM6 11735.2 H 0.059 1.93E−02 27.1 LYM12 11874.1 E0.475 2.60E−02 40.6 LYM129 12572.2 H 0.059 2.39E−02 26.6 LYM12 11873.4 E0.437 2.78E−02 29.5 LYM129 12571.3 H 0.061 5.64E−02 31 LYM12 11872.1 E0.419 3.43E−02 24.3 LYM132 12273.2 H 0.061 6.13E−02 32.2 LYM37 11803.2 E0.44 4.37E−02 30.4 LYM1 11602.1 H 0.057 6.26E−02 21.7 LYM134 12312.3 E0.413 4.44E−02 22.3 LYM5 12436.2 H 0.059 8.93E−02 27.3 LYM178 12164.2 E0.455 4.69E−02 34.8 CONTROL — H 0.046 — 0 LYM34 11903.3 E 0.418 4.86E−0224 LYM236 12594.3 A 0.008 1.51E−03 116.1 LYM41 11831.1 E 0.41 5.41E−0221.5 LYM254 12471.1 A 0.008 2.78E−03 98.7 LYM178 12161.1 E 0.4037.68E−02 19.6 LYM162 12231.1 A 0.006 3.13E−03 46.6 LYM41 11833.1 E 0.4158.54E−02 23.1 LYM42 11992.2 A 0.006 4.31E−03 47.3 CONTROL — E 0.337 — 0LYM148 12171.2 A 0.006 5.66E−03 53.1 LYM37 11801.1 F 6.047 6.62E−04 37LYM170 12452.3 A 0.008 1.06E−02 100.6 LYM34 11902.4 F 5.246 9.78E−0418.8 LYM250 12613.2 A 0.008 1.81E−02 93.6 LYM41 11831.5 F 5.45 2.57E−0323.5 LYM172 12301.3 A 0.005 2.24E−02 40.8 LYM41 11831.1 F 5.583 4.31E−0326.5 LYM206 12603.2 A 0.007 2.33E−02 69.1 LYM12 11873.4 F 5.776 1.16E−0230.8 LYM236 12592.3 A 0.011 2.33E−02 194.5 LYM37 11801.2 F 5.4111.89E−02 22.6 LYM140 12261.4 A 0.005 2.36E−02 37.6 LYM178 12161.1 F5.197 2.62E−02 17.7 LYM236 12591.1 A 0.008 4.87E−02 94.9 LYM35 11813.5 F5.421 3.01E−02 22.8 LYM172 12304.1 A 0.006 5.05E−02 46 LYM12 11871.1 F4.91 3.40E−02 11.2 LYM170 12453.3 A 0.008 5.28E−02 102.6 LYM34 11903.3 F5.271 5.80E−02 19.4 LYM99 12244.2 A 0.005 5.35E−02 31.8 LYM12 11872.1 F4.933 9.08E−02 11.8 LYM176 12385.1 A 0.008 6.09E−02 92.9 LYM37 11803.2 F5.325 9.97E−02 20.6 LYM254 12473.1 A 0.006 6.78E−02 51.1 CONTROL — F4.414 — 0 LYM206 12601.3 A 0.005 8.81E−02 23.5 LYM34 11902.2 G 0.511.12E−04 35.6 CONTROL — A 0.004 — 0 LYM132 12271.4 G 0.535 1.40E−04 42.2LYM250 12613.2 B 0.155 1.17E−03 115.8 LYM37 11801.1 G 0.53 3.38E−03 41.1LYM170 12452.3 B 0.15 1.88E−03 108.2 LYM35 11813.5 G 0.532 4.76E−03 41.6LYM140 12261.4 B 0.103 2.97E−03 42.9 LYM41 11831.5 G 0.485 5.92E−03 29.1LYM254 12471.1 B 0.146 4.61E−03 103.2 LYM34 11904.3 G 0.511 1.03E−02 36LYM42 11992.2 B 0.112 6.00E−03 55 LYM37 11801.2 G 0.553 2.50E−02 47.2LYM236 12594.3 B 0.166 7.83E−03 130.6 LYM35 11814.1 G 0.496 4.22E−0231.9 LYM148 12171.2 B 0.118 9.52E−03 63.8 LYM37 11803.2 G 0.46 4.24E−0222.3 LYM99 12244.2 B 0.094 1.23E−02 31 LYM35 11812.4 G 0.495 4.88E−0231.7 LYM89 12211.2 B 0.157 1.54E−02 117.7 LYM37 11802.2 G 0.698 5.08E−0285.6 LYM162 12231.1 B 0.109 1.59E−02 52 LYM178 12161.1 G 0.432 5.38E−0215 LYM236 12592.3 B 0.218 1.74E−02 202.4 LYM41 11831.1 G 0.467 8.64E−0224.4 LYM172 12304.1 B 0.118 2.52E−02 63.6 LYM178 12163.3 G 0.4398.80E−02 16.7 LYM176 12385.1 B 0.147 2.76E−02 103.9 LYM37 11803.1 G0.445 9.23E−02 18.3 LYM254 12473.1 B 0.123 3.29E−02 70.5 CONTROL — G0.376 — 0 LYM206 12603.2 B 0.139 3.64E−02 92.4 LYM37 11802.2 H 0.0718.35E−04 82.3 LYM236 12591.1 B 0.148 3.71E−02 105.8 LYM37 11801.1 H0.056 2.75E−03 44.2 LYM170 12453.3 B 0.156 4.30E−02 116.8 LYM37 11801.2H 0.054 6.30E−03 40.3 LYM250 12614.1 B 0.09 4.32E−02 24.8 LYM35 11813.5H 0.051 1.52E−02 32.4 LYM172 12302.2 B 0.089 4.68E−02 23.7 LYM13212271.4 H 0.052 1.70E−02 34.1 LYM250 12613.4 B 0.099 4.78E−02 37 LYM3711803.2 H 0.05 2.33E−02 29.6 LYM206 12601.3 B 0.1 5.38E−02 39.3 LYM3511812.4 H 0.052 2.59E−02 33.2 LYM140 12261.2 B 0.089 5.71E−02 23.4 LYM3411902.2 H 0.049 2.97E−02 27.4 LYM206 12603.1 B 0.088 6.78E−02 22.5 LYM3411904.3 H 0.05 7.81E−02 28.4 LYM170 12453.2 B 0.094 7.55E−02 30.7 LYM1211874.1 H 0.05 9.07E−02 30.1 LYM206 12602.1 B 0.123 8.33E−02 70.1 LYM3511814.1 H 0.047 9.82E−02 22.5 LYM170 12452.4 B 0.128 8.37E−02 77.1CONTROL — H 0.039 — 0 LYM140 12262.2 B 0.09 9.03E−02 24.7 LYM82 12203.5A 0.011 1.26E−03 111.5 LYM176 12384.1 B 0.096 9.40E−02 33 LYM268 12482.1A 0.007 2.56E−03 34.2 CONTROL — B 0.072 — 0 LYM82 12201.2 A 0.0085.53E−03 51.6 LYM172 12301.3 C 0.909 0.00E+00 131.8 LYM5 12436.1 A 0.0068.15E−03 24.2 LYM176 12384.1 C 0.869 0.00E+00 121.6 LYM86 12183.1 A0.007 8.76E−03 43.6 LYM206 12603.2 C 0.962 0.00E+00 145.4 LYM129 12573.1A 0.01 1.15E−02 91.5 LYM236 12591.1 C 1.008 0.00E+00 157.2 LYM26812484.2 A 0.009 2.45E−02 73.6 LYM236 12592.3 C 0.999 0.00E+00 154.8LYM268 12483.4 A 0.014 2.66E−02 180.3 LYM236 12594.3 C 0.862 0.00E+00119.8 LYM129 12572.2 A 0.007 2.78E−02 38.7 LYM250 12613.2 C 0.9370.00E+00 139 LYM8 11984.1 A 0.011 3.56E−02 125.9 LYM254 12471.1 C 0.8320.00E+00 112.2 LYM86 12183.3 A 0.007 9.36E−02 39.7 LYM170 12452.4 C0.784 1.00E−06 100.1 CONTROL — A 0.005 — 0 LYM170 12452.3 C 0.8261.00E−05 110.8 LYM268 12482.1 B 0.138 1.55E−03 47.8 LYM170 12453.2 C0.789 1.00E−05 101.4 LYM82 12203.5 B 0.189 5.29E−03 102.1 LYM148 12171.2C 0.809 1.10E−05 106.5 LYM86 12183.1 B 0.142 1.04E−02 51.8 LYM20612602.1 C 0.895 1.10E−05 128.4 LYM129 12573.1 B 0.171 1.16E−02 83.7LYM172 12304.1 C 0.71 1.30E−05 81 LYM268 12484.2 B 0.146 1.19E−02 56.8LYM162 12231.1 C 0.898 1.70E−05 129 LYM82 12201.2 B 0.133 1.75E−02 42.9LYM162 12231.2 C 0.856 2.40E−05 118.5 LYM268 12483.4 B 0.243 2.03E−02160.1 LYM176 12381.3 C 0.691 4.30E−05 76.2 LYM129 12572.2 B 0.1264.67E−02 35.3 LYM250 12614.1 C 0.74 8.00E−05 88.8 LYM5 12436.1 B 0.117.62E−02 18.2 LYM206 12603.3 C 0.736 1.02E−04 87.7 CONTROL — B 0.093 — 0LYM89 12214.2 C 0.713 1.44E−04 81.9 LYM268 12483.4 C 1.193 0.00E+00184.9 LYM176 12385.1 C 0.847 1.46E−04 116 LYM82 12203.5 C 0.933 1.00E−06122.9 LYM172 12302.2 C 0.777 1.54E−04 98.2 LYM8 11984.1 C 0.846 1.20E−05102.1 LYM254 12471.2 C 0.657 2.37E−04 67.6 LYM82 12203.2 C 1.0472.30E−05 149.9 LYM99 12244.2 C 0.665 5.09E−04 69.6 LYM268 12484.2 C0.749 4.40E−05 79 LYM250 12611.3 C 0.666 5.70E−04 69.8 LYM5 12436.2 C0.708 1.17E−04 69 LYM172 12301.2 C 0.621 6.43E−04 58.4 LYM44 11884.3 C0.683 5.09E−04 63.2 LYM170 12453.3 C 0.709 6.67E−04 80.9 LYM86 12183.3 C0.599 4.64E−03 43.1 LYM89 12214.1 C 0.694 7.89E−04 77.2 LYM129 12573.1 C0.634 4.95E−03 51.5 LYM236 12592.4 C 0.698 8.40E−04 78 LYM129 12572.2 C0.616 5.99E−03 47.2 LYM42 11992.2 C 0.75 8.94E−04 91.4 LYM86 12182.3 C0.585 1.21E−02 39.6 LYM140 12261.2 C 0.634 1.55E−03 61.8 LYM268 12481.3C 0.655 1.25E−02 56.5 LYM89 12214.3 C 0.636 1.76E−03 62.3 LYM5 12436.1 C0.592 1.26E−02 41.3 LYM89 12211.2 C 0.69 1.81E−03 76 LYM44 11882.1 C0.612 1.33E−02 46.2 LYM162 12233.2 C 0.594 2.55E−03 51.5 LYM268 12482.1C 0.558 3.20E−02 33.2 LYM99 12244.1 C 0.631 3.12E−03 60.9 LYM44 11885.3C 0.546 5.94E−02 30.3 LYM140 12261.4 C 0.614 3.48E−03 56.5 CONTROL — C0.419 — 0 LYM254 12472.3 C 0.609 4.02E−03 55.4 LYM268 12483.4 D 10.3192.40E−05 190.3 LYM162 12234.3 C 0.591 4.28E−03 50.8 LYM5 12436.2 D 6.0691.53E−03 70.7 LYM3 12041.2 C 0.584 5.59E−03 48.9 LYM44 11884.3 D 5.8762.29E−03 65.3 LYM99 12241.1 C 0.573 6.37E−03 46.2 LYM82 12203.5 D 8.172.69E−03 129.8 LYM89 12214.4 C 0.601 7.47E−03 53.3 LYM268 12484.2 D6.627 3.76E−03 86.4 LYM250 12613.4 C 0.598 7.72E−03 52.6 LYM86 12183.3 D5.313 3.87E−03 49.5 LYM290 12502.1 C 0.635 8.21E−03 61.9 LYM86 12182.3 D4.996 8.33E−03 40.6 LYM290 12501.3 C 0.636 1.00E−02 62.3 LYM129 12572.2D 5.336 1.25E−02 50.1 LYM148 12173.5 C 0.608 1.17E−02 55.2 LYM12912573.1 D 5.39 1.80E−02 51.6 LYM148 12173.1 C 0.555 1.44E−02 41.6 LYM512436.1 D 5.203 2.16E−02 46.4 LYM206 12601.3 C 0.606 1.63E−02 54.7 LYM8212203.2 D 9.172 2.69E−02 158 LYM148 12172.1 C 0.544 3.03E−02 38.8 LYM811984.1 D 7.277 3.07E−02 104.7 LYM254 12474.3 C 0.543 3.66E−02 38.4LYM44 11885.3 D 4.768 3.08E−02 34.1 LYM3 12041.1 C 0.531 3.68E−02 35.5LYM268 12482.1 D 4.714 3.75E−02 32.6 LYM99 12243.2 C 0.584 4.06E−02 48.9LYM44 11882.1 D 5.205 6.64E−02 46.4 CONTROL — C 0.392 — 0 CONTROL — D3.555 — 0 LYM176 12384.1 D 7.655 0.00E+00 132.7 LYM268 12483.4 E 0.5291.08E−02 41.8 LYM172 12304.1 D 6.298 1.30E−05 91.4 LYM44 11884.3 E 0.5042.21E−02 35.2 LYM170 12452.4 D 6.863 3.10E−05 108.6 LYM82 12203.2 E0.528 2.55E−02 41.7 LYM176 12381.3 D 6.039 3.20E−05 83.6 LYM82 12203.5 E0.494 6.19E−02 32.5 LYM254 12471.2 D 5.663 1.13E−04 72.2 LYM86 12182.3 E0.474 7.22E−02 27.2 LYM172 12301.3 D 7.853 3.12E−04 138.7 LYM86 12183.3E 0.469 9.75E−02 25.7 LYM172 12301.2 D 5.347 3.95E−04 62.5 CONTROL — E0.373 — 0 LYM254 12471.1 D 7.28 5.95E−04 121.3 LYM268 12483.4 F 6.5514.20E−05 48.7 LYM99 12241.1 D 4.885 1.02E−03 48.5 LYM82 12203.5 F 6.544.30E−05 48.4 LYM162 12233.2 D 5.095 1.13E−03 54.9 LYM82 12203.2 F 6.3662.44E−04 44.5 LYM236 12591.1 D 8.655 1.52E−03 163.1 LYM44 11884.3 F5.875 6.63E−04 33.4 LYM236 12594.3 D 7.796 2.20E−03 137 LYM86 12182.3 F5.586 2.72E−03 26.8 LYM162 12234.3 D 5.023 2.44E−03 52.7 LYM86 12183.3 F5.724 3.20E−03 29.9 LYM206 12603.2 D 8.33 2.58E−03 153.2 LYM8 11983.1 F5.556 3.24E−03 26.1 LYM148 12173.1 D 4.692 2.92E−03 42.6 LYM5 12436.1 F5.831 3.79E−03 32.3 LYM236 12592.3 D 8.564 2.99E−03 160.3 LYM268 12484.2F 5.898 5.85E−03 33.9 LYM3 12041.2 D 5.083 3.81E−03 54.5 LYM86 12181.2 F5.396 7.40E−03 22.5 LYM140 12261.4 D 5.321 3.93E−03 61.7 LYM129 12572.2F 5.555 8.48E−03 26.1 LYM250 12613.2 D 8.022 4.46E−03 143.9 LYM5 12432.2F 5.252 2.59E−02 19.2 LYM148 12171.2 D 7.076 4.80E−03 115.1 LYM4411882.1 F 5.409 3.28E−02 22.8 LYM170 12453.2 D 6.92 5.21E−03 110.4 LYM512432.1 F 5.116 3.85E−02 16.1 LYM89 12214.3 D 5.75 6.25E−03 74.8 LYM4411885.4 F 5.085 4.84E−02 15.4 LYM206 12603.3 D 6.599 8.50E−03 100.6LYM129 12573.1 F 5.082 5.14E−02 15.3 LYM89 12214.2 D 6.285 1.03E−02 91LYM5 12436.2 F 5.772 5.31E−02 31 LYM99 12244.2 D 5.742 1.05E−02 74.5LYM5 12435.1 F 5.498 6.21E−02 24.8 LYM250 12614.1 D 6.308 1.09E−02 91.8LYM8 11982.6 F 5.089 7.04E−02 15.5 LYM170 12452.3 D 7.21 1.17E−02 119.2LYM8 11984.1 F 5.999 9.59E−02 36.2 LYM140 12261.2 D 5.41 1.38E−02 64.5CONTROL — F 4.406 — 0 LYM254 12472.3 D 5.268 1.47E−02 60.1 LYM5 12436.1G 0.638 1.29E−04 50.3 LYM250 12611.3 D 5.796 1.51E−02 76.2 LYM12912573.1 G 0.849 1.56E−04 99.9 LYM89 12214.1 D 6.21 1.65E−02 88.8 LYM8212203.5 G 0.847 2.51E−04 99.4 LYM172 12302.2 D 6.672 1.89E−02 102.8LYM86 12183.3 G 0.687 4.03E−04 61.7 LYM206 12602.1 D 7.772 1.91E−02136.2 LYM268 12482.1 G 0.603 5.49E−04 42 LYM162 12231.1 D 7.885 1.92E−02139.7 LYM268 12483.4 G 1.054 6.89E−04 148 LYM3 12041.1 D 4.684 2.07E−0242.4 LYM82 12201.2 G 0.643 1.52E−03 51.4 LYM162 12231.2 D 7.359 2.76E−02123.7 LYM268 12484.2 G 0.768 1.52E−03 80.8 LYM236 12592.4 D 6.2242.84E−02 89.2 LYM86 12183.1 G 0.602 2.17E−03 41.6 LYM99 12244.1 D 5.4672.84E−02 66.2 LYM44 11882.1 G 0.544 4.43E−03 28.1 LYM176 12385.1 D 7.5032.87E−02 128.1 LYM44 11885.3 G 0.552 4.98E−03 29.9 LYM290 12501.2 D4.367 2.94E−02 32.8 LYM82 12204.6 G 0.558 7.03E−03 31.3 LYM148 12172.1 D4.711 3.20E−02 43.2 LYM129 12572.2 G 0.671 7.23E−03 57.9 LYM170 12453.3D 6.282 3.38E−02 91 LYM44 11884.3 G 0.532 7.42E−03 25.3 LYM250 12613.4 D5.345 3.40E−02 62.5 LYM5 12436.2 G 0.545 8.39E−03 28.2 LYM89 12211.2 D6.247 4.75E−02 89.9 LYM8 11984.1 G 0.849 1.84E−02 99.8 LYM89 12214.4 D4.932 4.87E−02 49.9 LYM86 12182.3 G 0.526 2.43E−02 23.7 LYM42 11992.2 D6.54 5.04E−02 98.8 LYM6 11735.2 G 0.49 8.02E−02 15.4 LYM148 12173.5 D5.372 6.79E−02 63.3 LYM82 12203.2 G 0.834 8.07E−02 96.2 LYM254 12474.3 D4.625 6.91E−02 40.6 CONTROL — G 0.425 — 0 LYM290 12502.1 D 5.37 7.87E−0263.2 LYM129 12573.1 H 0.085 0.00E+00 100.9 LYM206 12601.3 D 5.2968.29E−02 61 LYM268 12483.4 H 0.108 0.00E+00 156.5 CONTROL — D 3.29 — 0LYM8 11984.1 H 0.089 0.00E+00 110.3 LYM236 12591.1 E 0.594 2.26E−03 47.4LYM82 12203.5 H 0.088 1.00E−06 108.4 LYM172 12302.2 E 0.596 3.04E−0347.9 LYM268 12484.2 H 0.074 2.30E−05 75.8 LYM176 12381.3 E 0.5774.24E−03 43.2 LYM86 12183.3 H 0.066 2.60E−04 56.3 LYM140 12261.2 E 0.5664.95E−03 40.6 LYM268 12482.1 H 0.062 1.28E−03 46.3 LYM99 12244.1 E 0.5666.16E−03 40.6 LYM129 12572.2 H 0.065 1.65E−03 53.7 LYM172 12304.1 E0.564 7.50E−03 40.1 LYM82 12203.2 H 0.087 1.78E−03 106.5 LYM170 12453.2E 0.563 7.87E−03 39.8 LYM5 12436.1 H 0.06 2.89E−03 41.7 LYM170 12452.4 E0.567 8.02E−03 40.8 LYM86 12183.1 H 0.06 5.56E−03 41 LYM254 12472.3 E0.553 8.60E−03 37.2 LYM5 12436.2 H 0.059 8.00E−03 39 LYM148 12171.2 E0.563 9.63E−03 39.9 LYM82 12201.2 H 0.059 8.96E−03 40.3 LYM206 12602.1 E0.562 1.25E−02 39.6 LYM82 12204.6 H 0.057 1.25E−02 34.6 LYM99 12244.2 E0.54 1.39E−02 34 LYM44 11884.3 H 0.056 1.64E−02 32.6 LYM236 12592.3 E0.555 2.06E−02 37.7 LYM268 12481.3 H 0.061 2.53E−02 44.7 LYM250 12613.2E 0.542 2.10E−02 34.5 LYM44 11885.3 H 0.056 2.57E−02 33.6 LYM254 12471.2E 0.55 2.13E−02 36.6 LYM44 11882.1 H 0.055 3.23E−02 29.4 LYM206 12603.2E 0.557 2.43E−02 38.4 LYM5 12432.2 H 0.057 5.25E−02 34.7 LYM170 12452.3E 0.538 2.59E−02 33.7 LYM86 12182.3 H 0.053 7.08E−02 24.8 LYM89 12214.4E 0.557 2.64E−02 38.2 CONTROL — H 0.042 — 0 LYM236 12592.4 E 0.5342.66E−02 32.6 LYM89 12214.3 A 0.006 5.91E−04 43.4 LYM206 12603.3 E 0.5422.79E−02 34.5 LYM250 12611.3 A 0.006 4.67E−03 44.1 LYM172 12301.3 E0.527 3.29E−02 30.7 CONTROL — A 0.004 — 0 LYM172 12301.2 E 0.5233.72E−02 29.8 LYM250 12611.3 C 0.724 1.68E−02 39.6 LYM148 12173.1 E0.547 3.85E−02 35.7 CONTROL — C 0.519 — 0 LYM89 12214.1 E 0.554 3.89E−0237.6 LYM250 12611.3 D 6.633 3.09E−02 40.5 LYM89 12211.2 E 0.529 3.96E−0231.3 CONTROL — D 4.721 — 0 LYM250 12614.1 E 0.535 4.14E−02 32.8 LYM25012611.3 E 0.531 7.01E−02 18.9 LYM162 12231.1 E 0.54 4.51E−02 34.1CONTROL — E 0.447 — 0 LYM42 11992.2 E 0.528 5.37E−02 31.2 LYM250 12611.3F 6.627 1.48E−03 22.7 LYM206 12601.3 E 0.51 6.40E−02 26.6 LYM236 12591.1F 6.197 1.53E−02 14.7 LYM250 12611.3 E 0.525 6.99E−02 30.4 LYM99 12243.2F 6.22 2.59E−02 15.1 LYM206 12604.3 E 0.503 7.47E−02 24.9 CONTROL — F5.402 — 0 LYM236 12594.3 E 0.51 8.71E−02 26.7 LYM250 12611.3 G 0.6334.48E−03 30.7 LYM176 12385.1 E 0.526 8.97E−02 30.6 LYM89 12214.3 G 0.6323.84E−02 30.6 LYM254 12471.1 E 0.513 9.45E−02 27.4 CONTROL — G 0.484 — 0LYM176 12384.1 E 0.507 9.46E−02 26 LYM250 12611.3 H 0.066 4.26E−02 29.7CONTROL — E 0.403 — 0 CONTROL — H 0.051 — 0 LYM170 12453.2 F 7.2461.00E−06 71.9 LYM130 12332.2 A 0.008 7.52E−04 183.7 LYM170 12452.4 F7.207 1.00E−06 71 LYM102 12222.1 A 0.006 1.71E−03 86.6 LYM236 12591.1 F7.239 1.00E−06 71.7 LYM130 12334.1 A 0.007 2.90E−03 123.4 LYM148 12171.2F 6.951 3.00E−06 64.9 LYM138 12561.3 A 0.005 3.10E−03 74.1 LYM17212301.3 F 7.006 3.00E−06 66.2 LYM141 12404.2 A 0.006 8.08E−03 106.7LYM99 12244.2 F 6.7 3.00E−06 59 LYM106 12142.2 A 0.004 1.83E−02 48.1LYM176 12381.3 F 7.089 4.00E−06 68.2 LYM138 12566.1 A 0.004 1.99E−0246.4 LYM176 12384.1 F 7.171 3.30E−05 70.1 LYM100 12133.3 A 0.0052.31E−02 62.3 LYM99 12244.1 F 6.715 3.40E−05 59.3 LYM141 12404.3 A 0.0083.47E−02 151 LYM254 12472.3 F 6.573 3.80E−05 56 LYM106 12144.3 A 0.0053.82E−02 59 LYM172 12304.1 F 6.852 4.90E−05 62.6 LYM119 12462.1 A 0.0046.49E−02 46.4 LYM140 12261.2 F 6.623 5.40E−05 57.1 LYM130 12331.3 A0.004 7.03E−02 48.1 LYM170 12452.3 F 6.777 6.70E−05 60.8 LYM137 12152.1A 0.008 7.19E−02 160.3 LYM3 12041.1 F 6.228 7.30E−05 47.8 LYM100 12131.2A 0.004 7.74E−02 45.6 LYM148 12173.5 F 6.639 7.60E−05 57.5 LYM10212221.2 A 0.007 8.15E−02 117.6 LYM206 12603.2 F 7.105 1.19E−04 68.6LYM130 12332.1 A 0.004 9.91E−02 48.1 LYM254 12471.1 F 6.781 1.27E−0460.9 CONTROL — A 0.003 — 0 LYM89 12214.2 F 7.108 1.46E−04 68.6 LYM14112404.2 B 0.134 1.20E−05 79 LYM206 12603.1 F 5.793 2.05E−04 37.4 LYM13812561.3 B 0.114 2.78E−04 52.9 LYM250 12613.2 F 6.782 2.08E−04 60.9LYM102 12222.1 B 0.113 9.40E−04 51.4 LYM140 12261.4 F 6.079 2.18E−0444.2 LYM130 12332.1 B 0.117 7.14E−03 55.7 LYM172 12301.2 F 6.3172.83E−04 49.9 LYM130 12332.2 B 0.189 1.06E−02 152.1 LYM290 12501.2 F5.648 3.03E−04 34 LYM106 12142.2 B 0.104 1.16E−02 38.3 LYM290 12501.3 F6.472 3.12E−04 53.6 LYM130 12334.1 B 0.176 1.48E−02 135 LYM236 12594.3 F7.033 3.99E−04 66.9 LYM141 12404.3 B 0.155 3.07E−02 106.5 LYM89 12211.2F 6.813 4.03E−04 61.6 LYM138 12566.1 B 0.1 3.93E−02 33.3 LYM162 12231.1F 7.203 5.06E−04 70.9 LYM137 12152.1 B 0.164 4.75E−02 119.7 LYM14812172.1 F 5.789 5.46E−04 37.3 LYM100 12131.2 B 0.108 5.45E−02 44.1 LYM9912241.1 F 5.77 6.25E−04 36.9 LYM119 12462.1 B 0.11 6.36E−02 46.8 LYM20612602.1 F 6.96 6.53E−04 65.1 LYM113 12444.5 B 0.144 6.90E−02 91.8 LYM23612592.4 F 6.741 7.46E−04 59.9 CONTROL — B 0.075 — 0 LYM236 12592.3 F6.471 8.01E−04 53.5 LYM137 12153.1 C 0.75 3.30E−05 73.3 LYM162 12231.2 F6.805 8.61E−04 61.4 LYM102 12222.1 C 0.681 3.41E−04 57.4 LYM250 12613.4F 6.196 1.05E−03 47 LYM141 12404.3 C 0.739 1.80E−03 70.8 LYM176 12385.1F 6.842 1.76E−03 62.3 LYM137 12152.1 C 0.63 2.56E−03 45.6 LYM172 12302.2F 6.851 1.79E−03 62.5 LYM138 12561.3 C 0.615 2.31E−02 42.1 LYM25012614.1 F 6.733 1.94E−03 59.7 LYM130 12332.2 C 0.588 2.32E−02 36 LYM20612603.3 F 6.666 1.97E−03 58.2 LYM102 12221.2 C 0.578 5.38E−02 33.7 LYM4211992.2 F 6.765 2.50E−03 60.5 LYM100 12133.3 C 0.555 5.62E−02 28.4 LYM8912214.1 F 6.519 2.76E−03 54.7 LYM141 12404.2 C 0.547 7.44E−02 26.5LYM254 12471.2 F 6.589 2.87E−03 56.3 CONTROL — C 0.433 — 0 LYM16212234.3 F 5.858 3.38E−03 39 LYM102 12222.1 D 5.942 1.65E−03 46.8 LYM312041.2 F 5.203 3.62E−03 23.4 LYM137 12152.1 D 5.648 2.45E−03 39.5LYM250 12611.3 F 6.664 3.93E−03 58.1 LYM137 12153.1 D 6.551 2.59E−0361.8 LYM206 12601.3 F 5.605 5.24E−03 33 LYM100 12133.3 D 5.099 5.27E−0226 LYM89 12214.3 F 5.837 6.12E−03 38.5 LYM130 12332.2 D 5.253 6.20E−0229.8 LYM162 12233.2 F 5.958 8.02E−03 41.4 CONTROL — D 4.048 — 0 LYM25412474.3 F 5.758 8.41E−03 36.6 LYM137 12153.1 E 0.569 1.28E−03 41.7 LYM312043.2 F 4.993 1.23E−02 18.5 LYM141 12404.3 E 0.559 1.44E−02 39.3 LYM4211992.1 F 5.514 1.45E−02 30.8 LYM138 12561.3 E 0.51 3.15E−02 27 LYM29012502.1 F 5.909 2.95E−02 40.2 LYM102 12222.1 E 0.501 4.11E−02 24.8LYM148 12173.1 F 6.086 3.14E−02 44.4 LYM100 12133.3 E 0.493 5.35E−0222.9 LYM206 12604.3 F 4.959 4.80E−02 17.7 CONTROL — E 0.401 — 0 LYM14812174.1 F 4.971 6.23E−02 17.9 LYM138 12561.3 F 6.649 2.18E−03 31.5 LYM9912243.2 F 5.675 6.51E−02 34.6 LYM100 12133.3 F 6.469 2.22E−03 27.9LYM140 12262.3 F 5.437 8.77E−02 29 LYM138 12562.1 F 5.957 5.93E−03 17.8LYM42 11994.1 F 5.068 9.11E−02 20.2 LYM102 12222.1 F 6.27 6.30E−03 24CONTROL — F 4.215 — 0 LYM137 12153.1 F 6.743 9.51E−03 33.3 LYM25412471.1 G 0.773 3.00E−06 72.9 LYM113 12444.5 F 5.957 1.07E−02 17.8 LYM9912244.2 G 0.569 1.23E−03 27.3 LYM102 12221.2 F 5.892 1.12E−02 16.5LYM206 12601.3 G 0.63 1.78E−03 40.9 LYM137 12152.1 F 5.949 1.63E−02 17.6LYM170 12452.3 G 1.024 2.21E−03 129 LYM119 12461.4 F 5.793 2.27E−02 14.5LYM176 12384.1 G 0.675 2.30E−03 51 LYM130 12332.2 F 5.638 4.49E−02 11.5LYM250 12613.2 G 0.886 2.49E−03 98.2 LYM113 12443.1 F 5.681 8.19E−0212.3 LYM42 11992.2 G 0.688 4.52E−03 53.8 CONTROL — F 5.058 — 0 LYM17212301.2 G 0.555 4.63E−03 24.2 LYM102 12222.1 G 0.641 5.60E−03 61.2LYM236 12594.3 G 0.923 4.63E−03 106.6 LYM138 12561.3 G 0.563 7.37E−0341.4 LYM162 12231.1 G 0.704 5.43E−03 57.5 LYM130 12332.2 G 0.7338.67E−03 84.3 LYM148 12171.2 G 0.744 6.77E−03 66.5 LYM137 12152.1 G0.752 1.54E−02 88.9 LYM236 12592.3 G 1.063 6.78E−03 137.7 LYM141 12404.2G 0.538 2.41E−02 35.3 LYM172 12304.1 G 0.623 7.31E−03 39.4 LYM13812566.1 G 0.5 2.70E−02 25.7 LYM206 12603.2 G 0.749 9.52E−03 67.5 LYM13012334.1 G 0.544 4.27E−02 36.6 LYM176 12385.1 G 0.997 1.09E−02 123.1LYM143 12521.2 G 0.478 7.49E−02 20.2 LYM250 12614.2 G 0.572 1.38E−0227.9 LYM138 12562.1 G 0.476 9.14E−02 19.7 LYM89 12214.2 G 0.547 1.62E−0222.4 CONTROL — G 0.398 — 0 LYM250 12613.4 G 0.681 1.94E−02 52.3 LYM14112404.3 H 0.077 5.80E−05 96.5 LYM170 12452.4 G 0.76 2.00E−02 70 LYM10212222.1 H 0.065 8.00E−05 65.8 LYM89 12211.2 G 0.714 2.05E−02 59.8 LYM13712152.1 H 0.073 8.50E−05 85.8 LYM140 12261.4 G 0.701 2.10E−02 56.9LYM130 12332.2 H 0.068 9.70E−05 73.7 LYM170 12453.2 G 0.642 2.18E−0243.5 LYM137 12153.1 H 0.066 1.26E−03 66.9 LYM140 12262.2 G 0.5692.43E−02 27.3 LYM138 12561.3 H 0.054 1.01E−02 37.1 LYM170 12453.3 G0.909 2.78E−02 103.3 LYM141 12404.2 H 0.053 1.35E−02 34.4 LYM236 12591.1G 0.874 2.83E−02 95.5 LYM102 12221.2 H 0.058 1.40E−02 46.1 LYM89 12214.4G 0.537 2.84E−02 20.2 LYM130 12334.1 H 0.052 3.72E−02 30.7 LYM99 12243.1G 0.623 3.48E−02 39.3 LYM138 12562.1 H 0.05 4.54E−02 26 LYM89 12214.3 G0.636 4.21E−02 42.2 LYM138 12566.1 H 0.048 7.16E−02 22.8 LYM176 12384.2G 0.591 4.33E−02 32.1 LYM100 12133.3 H 0.049 7.66E−02 25.2 LYM20612603.3 G 0.585 4.64E−02 31 LYM106 12144.3 H 0.049 8.55E−02 24 LYM14012261.2 G 0.51 5.15E−02 14 CONTROL — H 0.039 — 0 LYM176 12382.2 G 0.5855.38E−02 30.8 LYM153 12321.2 A 0.012 9.21E−03 102.4 LYM42 11992.1 G0.641 5.45E−02 43.4 LYM152 12376.1 A 0.011 4.22E−02 75.2 LYM148 12173.5G 0.673 5.74E−02 50.6 LYM148 12174.1 A 0.008 5.19E−02 28.7 LYM89 12214.1G 0.631 5.75E−02 41.2 LYM140 12262.2 A 0.008 9.10E−02 23.8 LYM20612602.1 G 0.732 5.75E−02 63.6 CONTROL — A 0.006 — 0 LYM254 12473.1 G0.568 5.82E−02 27 LYM153 12321.2 B 0.245 2.61E−03 69.9 LYM3 12041.2 G0.665 6.39E−02 48.8 LYM152 12376.1 B 0.203 8.19E−02 40.9 LYM42 11993.1 G0.528 6.87E−02 18.2 CONTROL — B 0.144 — 0 LYM172 12301.3 G 0.5498.21E−02 22.8 LYM152 12376.1 C 1.184 0.00E+00 138.6 LYM176 12381.3 G0.563 8.39E−02 26 LYM153 12321.2 C 1.041 1.30E−05 109.9 LYM290 12504.1 G0.659 8.59E−02 47.4 LYM170 12452.3 C 0.84 2.70E−05 69.4 CONTROL — G0.447 — 0 LYM149 12344.2 C 0.829 5.50E−05 67.1 LYM170 12452.3 H 0.0990.00E+00 113.2 LYM172 12301.2 C 0.905 6.80E−05 82.3 LYM236 12592.3 H0.109 0.00E+00 135.8 LYM174 12412.1 C 0.809 9.50E−05 63.2 LYM250 12613.2H 0.088 0.00E+00 90.5 LYM153 12322.1 C 0.877 1.92E−04 76.8 LYM23612594.3 H 0.088 1.00E−06 89 LYM172 12301.3 C 0.86 2.07E−04 73.3 LYM25412471.1 H 0.077 1.00E−06 64.9 LYM176 12381.3 C 0.781 3.32E−04 57.5LYM176 12385.1 H 0.096 6.00E−06 106.2 LYM170 12454.2 C 0.766 5.34E−0454.4 LYM206 12603.2 H 0.078 1.20E−05 68.2 LYM174 12411.3 C 0.7481.82E−03 50.8 LYM170 12453.3 H 0.092 7.00E−05 97.6 LYM162 12234.4 C0.743 2.64E−03 49.7 LYM170 12452.4 H 0.078 8.10E−05 67.9 LYM289 12493.2C 0.747 3.09E−03 50.6 LYM236 12591.1 H 0.087 1.34E−04 87.2 LYM17412411.2 C 0.785 4.17E−03 58.3 LYM162 12231.1 H 0.071 2.54E−04 52.4LYM111 12254.3 C 0.764 4.75E−03 54 LYM89 12211.2 H 0.071 5.66E−04 52LYM148 12174.1 C 0.725 5.96E−03 46.1 LYM42 11992.2 H 0.066 5.77E−04 43LYM162 12234.3 C 0.733 1.17E−02 47.7 LYM206 12601.3 H 0.065 6.02E−0439.1 LYM148 12171.2 C 0.684 2.29E−02 37.8 LYM148 12171.2 H 0.0699.52E−04 49.3 LYM105 12293.1 C 0.658 2.67E−02 32.6 LYM176 12384.1 H0.066 1.86E−03 42.7 LYM162 12231.2 C 0.68 2.78E−02 37.1 LYM206 12602.1 H0.073 2.16E−03 58.3 LYM174 12414.3 C 0.65 5.52E−02 30.9 LYM172 12304.1 H0.063 2.61E−03 36.2 LYM170 12452.4 C 0.636 5.67E−02 28.2 LYM250 12613.4H 0.066 2.68E−03 43 LYM153 12323.2 C 0.684 5.84E−02 37.9 LYM170 12453.2H 0.064 3.33E−03 38.6 LYM148 12173.5 C 0.652 6.99E−02 31.4 LYM14012261.4 H 0.066 4.14E−03 41.3 LYM290 12502.4 C 0.635 7.97E−02 28.1 LYM9912243.1 H 0.063 6.82E−03 35.1 LYM254 12474.4 C 0.617 8.58E−02 24.4 LYM9912244.2 H 0.059 7.05E−03 27.3 LYM148 12173.1 C 0.632 9.21E−02 27.3 LYM8912214.1 H 0.065 7.10E−03 40.5 CONTROL — C 0.496 — 0 LYM206 12603.3 H0.061 8.74E−03 31.6 LYM152 12376.1 D 10.184 0.00E+00 134.7 LYM25012614.2 H 0.06 9.60E−03 29.4 LYM170 12452.3 D 7.08 7.80E−05 63.2 LYM4211992.1 H 0.064 1.49E−02 37.4 LYM176 12381.3 D 6.67 2.52E−04 53.7 LYM25412473.1 H 0.06 1.84E−02 28.6 LYM149 12344.2 D 7.182 2.74E−04 65.5 LYM29012504.1 H 0.065 2.04E−02 39.9 LYM174 12412.1 D 6.751 3.53E−04 55.6 LYM8912214.3 H 0.061 3.34E−02 30.8 LYM170 12454.2 D 6.626 3.98E−04 52.7LYM172 12301.2 H 0.057 3.68E−02 22.3 LYM174 12411.3 D 6.497 3.90E−0349.7 LYM42 11993.1 H 0.058 3.99E−02 24.2 LYM289 12493.2 D 6.469 8.75E−0349.1 LYM89 12214.4 H 0.057 4.67E−02 22.5 LYM162 12234.4 D 6.253 1.01E−0244.1 LYM148 12173.5 H 0.062 4.81E−02 33.2 LYM105 12293.1 D 5.67 1.26E−0230.7 LYM140 12261.2 H 0.056 5.27E−02 19.9 LYM172 12301.3 D 7.4121.63E−02 70.8 LYM236 12592.4 H 0.061 6.49E−02 30.4 LYM172 12301.2 D7.674 1.83E−02 76.9 LYM250 12614.1 H 0.055 9.32E−02 19.6 LYM153 12321.2D 8.901 1.85E−02 105.2 LYM176 12381.3 H 0.056 9.61E−02 20.1 LYM15312322.1 D 7.58 2.24E−02 74.7 LYM290 12501.3 H 0.063 9.74E−02 35.7 LYM14812174.1 D 6.39 2.38E−02 47.3 CONTROL — H 0.046 — 0 LYM254 12474.4 D5.377 2.95E−02 23.9 LYM90 12392.1 A 0.005 1.00E−06 108.9 LYM111 12254.3D 6.642 3.13E−02 53.1 LYM213 12842.9 A 0.004 5.60E−05 48.5 LYM17012452.4 D 5.438 5.31E−02 25.3 LYM107 12633.4 A 0.006 1.12E−04 153.5LYM148 12171.2 D 6.008 5.50E−02 38.5 LYM157 13341.1 A 0.006 1.62E−03130.7 LYM174 12411.2 D 6.703 6.07E−02 54.5 LYM90 12394.2 A 0.0052.24E−03 78.2 LYM162 12231.2 D 5.948 7.11E−02 37.1 LYM107 12631.4 A0.005 9.45E−03 104 LYM162 12234.3 D 6.319 8.38E−02 45.6 LYM180 13441.7 A0.004 1.15E−02 58.4 LYM172 12304.1 D 5.126 9.20E−02 18.2 LYM90 12395.3 A0.005 1.27E−02 115.8 CONTROL — D 4.339 — 0 LYM248 13501.6 A 0.0041.40E−02 74.3 LYM176 12381.3 E 0.57 2.35E−02 42.8 LYM52 12895.7 A 0.0051.64E−02 87.1 LYM172 12301.2 E 0.563 3.24E−02 41.1 LYM52 12894.6 A 0.0052.41E−02 93.1 LYM174 12412.1 E 0.56 3.53E−02 40.3 LYM213 12841.8 A 0.0072.71E−02 161.4 LYM153 12322.1 E 0.547 5.02E−02 37.1 LYM68 11942.2 A0.004 3.03E−02 77.2 LYM254 12474.4 E 0.545 5.08E−02 36.5 LYM157 13341.3A 0.007 3.06E−02 193.1 LYM111 12254.3 E 0.542 6.45E−02 35.8 LYM18013441.5 A 0.003 3.17E−02 20.8 LYM170 12454.2 E 0.537 6.57E−02 34.5 LYM5212891.8 A 0.007 3.60E−02 183.2 LYM172 12301.3 E 0.543 6.79E−02 36.1LYM68 11943.5 A 0.004 3.69E−02 46.5 LYM148 12174.1 E 0.535 6.85E−02 34LYM213 12841.6 A 0.008 3.70E−02 235.6 LYM152 12376.1 E 0.543 7.05E−0236.1 LYM117 13622.6 A 0.005 4.17E−02 85.1 LYM174 12411.2 E 0.5357.56E−02 34.1 LYM117 13621.8 A 0.004 4.82E−02 57.4 LYM153 12321.2 E0.543 7.70E−02 36.1 LYM52 12894.8 A 0.008 5.80E−02 217.8 LYM170 12452.3E 0.53 8.57E−02 32.8 LYM68 11941.3 A 0.004 5.93E−02 41.6 LYM148 12171.2E 0.523 9.20E−02 31.1 LYM248 13502.7 A 0.004 6.41E−02 65.3 CONTROL — E0.399 — 0 LYM117 13624.4 A 0.004 7.16E−02 72.3 LYM149 12344.2 F 6.8011.57E−03 33.2 LYM52 12894.7 A 0.006 7.32E−02 152.5 LYM152 12376.1 F7.023 1.62E−03 37.5 LYM157 13341.4 A 0.005 7.51E−02 106.9 LYM148 12171.2F 6.663 2.42E−03 30.5 LYM213 12841.7 A 0.005 8.38E−02 114.9 LYM25412474.4 F 6.671 2.45E−03 30.7 LYM180 13443.7 A 0.003 8.44E−02 28.7LYM174 12412.1 F 6.791 2.67E−03 33 LYM180 13442.6 A 0.004 9.89E−02 50.5LYM170 12454.2 F 6.641 2.92E−03 30.1 CONTROL — A 0.003 — 0 LYM17012452.3 F 6.742 3.91E−03 32 LYM90 12392.1 B 0.152 1.06E−03 81.1 LYM17212301.3 F 6.706 5.41E−03 31.3 LYM107 12631.4 B 0.136 2.69E−03 61.9LYM148 12174.1 F 6.449 5.65E−03 26.3 LYM90 12395.3 B 0.135 5.72E−03 60.8LYM153 12321.2 F 6.678 5.68E−03 30.8 LYM157 13341.1 B 0.146 1.69E−0273.9 LYM153 12322.1 F 6.443 5.80E−03 26.2 LYM213 12841.6 B 0.2031.93E−02 141.6 LYM176 12381.3 F 6.442 5.82E−03 26.2 LYM117 13621.8 B0.105 2.79E−02 24.6 LYM289 12493.2 F 6.37 7.79E−03 24.8 LYM107 12633.4 B0.144 3.61E−02 71.1 LYM172 12301.2 F 6.401 8.13E−03 25.4 LYM68 11942.2 B0.111 4.71E−02 31.8 LYM174 12414.3 F 6.259 1.53E−02 22.6 LYM52 12894.6 B0.131 4.73E−02 55.6 LYM174 12411.2 F 6.338 1.62E−02 24.1 LYM52 12894.8 B0.184 4.84E−02 118.7 LYM148 12173.5 F 6.268 1.64E−02 22.7 LYM157 13341.3B 0.165 5.02E−02 96.8 LYM140 12262.3 F 6.2 1.65E−02 21.4 LYM52 12894.7 B0.164 5.10E−02 94.7 LYM111 12254.3 F 6.352 1.66E−02 24.4 LYM52 12891.8 B0.147 5.39E−02 75.3 LYM176 12384.1 F 6.087 2.67E−02 19.2 LYM90 12394.2 B0.11 5.40E−02 30.6 LYM170 12453.2 F 6.098 3.46E−02 19.4 LYM52 12895.7 B0.15 5.54E−02 78.1 LYM111 12252.2 F 6.029 3.90E−02 18.1 LYM248 13502.7 B0.12 6.58E−02 43.3 LYM162 12234.4 F 5.98 4.10E−02 17.1 LYM213 12842.9 B0.099 6.68E−02 17.3 LYM153 12323.2 F 6.035 4.13E−02 18.2 LYM117 13622.6B 0.136 6.92E−02 61.7 LYM162 12234.3 F 6.276 4.14E−02 22.9 LYM21312841.8 B 0.186 9.20E−02 121.5 LYM170 12452.4 F 5.96 4.49E−02 16.7CONTROL — B 0.084 — 0 LYM149 12343.2 F 6.255 5.80E−02 22.5 LYM10712633.4 C 0.991 0.00E+00 94.3 LYM162 12231.2 F 6.019 6.32E−02 17.9LYM107 12631.4 C 0.944 0.00E+00 85.1 LYM152 12373.2 F 5.846 7.37E−0214.5 LYM52 12894.6 C 1.012 0.00E+00 98.3 LYM289 12493.6 F 5.787 9.53E−0213.3 LYM52 12891.8 C 0.928 0.00E+00 81.9 CONTROL — F 5.106 — 0 LYM6811942.2 C 0.98 0.00E+00 92.1 LYM152 12376.1 G 0.993 4.96E−04 50.8 LYM5212894.8 C 0.954 1.00E−06 87 LYM153 12321.2 G 1.048 4.01E−03 59.2 LYM21312841.6 C 0.87 3.00E−06 70.5 LYM148 12174.1 G 0.916 6.30E−03 39.2 LYM9012392.1 C 0.869 1.10E−05 70.4 LYM290 12502.4 G 0.799 4.73E−02 21.3LYM157 13341.3 C 0.936 3.10E−05 83.5 LYM172 12301.2 G 0.862 5.63E−0230.9 LYM157 13341.1 C 0.823 1.04E−04 61.3 LYM140 12262.2 G 0.8148.61E−02 23.6 LYM90 12395.3 C 0.82 1.17E−04 60.6 LYM174 12411.3 G 0.8679.28E−02 31.7 LYM157 13341.4 C 0.812 1.51E−04 59.2 CONTROL — G 0.658 — 0LYM90 12394.2 C 0.779 2.54E−04 52.8 LYM152 12376.1 H 0.103 1.39E−04 65.4LYM68 11941.4 C 0.788 3.36E−04 54.5 LYM153 12321.2 H 0.106 2.48E−04 69.7LYM248 13501.6 C 0.784 5.63E−04 53.7 LYM172 12301.2 H 0.088 1.64E−02 41LYM107 12631.1 C 0.764 6.45E−04 49.7 LYM148 12174.1 H 0.086 1.81E−0238.1 LYM117 13622.6 C 0.74 1.38E−03 45.1 LYM174 12411.3 H 0.085 4.51E−0236.4 LYM52 12895.7 C 0.724 2.87E−03 42 CONTROL — H 0.063 — 0 LYM5212894.7 C 0.741 3.13E−03 45.2 LYM175 12651.2 A 0.005 1.27E−03 85.3 LYM9012393.1 C 0.728 8.19E−03 42.6 LYM107 12632.1 A 0.005 7.98E−03 96.3LYM157 13342.4 C 0.71 1.13E−02 39.2 LYM203 12663.2 A 0.006 1.07E−02104.6 LYM107 12631.2 C 0.671 2.27E−02 31.6 LYM128 12642.1 A 0.0043.17E−02 53.2 LYM213 12841.7 C 0.68 2.56E−02 33.4 LYM128 12641.3 A 0.0045.95E−02 64.2 LYM68 11942.3 C 0.679 3.65E−02 33 LYM175 12654.4 A 0.0047.53E−02 47.7 LYM90 12395.1 C 0.676 5.36E−02 32.6 CONTROL — A 0.003 — 0LYM68 11941.3 C 0.644 5.48E−02 26.2 LYM107 12631.1 B 0.092 9.39E−03 28.3LYM248 13503.5 C 0.647 6.20E−02 26.8 LYM175 12654.4 B 0.112 1.18E−0255.8 LYM117 13621.8 C 0.647 6.25E−02 26.8 LYM203 12663.2 B 0.1221.66E−02 69.5 LYM117 13624.7 C 0.636 7.06E−02 24.6 LYM107 12632.1 B0.125 2.43E−02 73.7 LYM117 13623.9 C 0.629 9.82E−02 23.2 LYM175 12651.2B 0.117 2.91E−02 62.4 CONTROL — C 0.51 — 0 LYM128 12642.1 B 0.0963.18E−02 33.2 LYM213 12841.6 D 7.638 4.50E−05 69.8 LYM128 12641.3 B0.096 6.27E−02 33.4 LYM117 13622.6 D 6.219 9.60E−05 38.3 LYM203 12662.2B 0.15 7.88E−02 108.2 LYM107 12631.2 D 5.852 3.86E−04 30.1 CONTROL — B0.072 — 0 LYM68 11942.2 D 8.371 4.18E−04 86.1 LYM128 12642.1 C 0.594.98E−04 67 LYM52 12891.8 D 8.048 4.29E−04 78.9 LYM203 12663.2 C 0.4962.37E−02 40.5 LYM90 12394.2 D 6.751 1.42E−03 50.1 LYM203 12662.2 C 0.5295.42E−02 49.7 LYM107 12631.1 D 6.531 2.91E−03 45.2 LYM128 12641.3 C0.447 7.46E−02 26.7 LYM52 12895.7 D 6.183 5.76E−03 37.5 LYM107 12631.2 C0.482 8.17E−02 36.6 LYM52 12894.6 D 8.572 6.41E−03 90.6 CONTROL — C0.353 — 0 LYM107 12631.4 D 8.249 7.31E−03 83.4 LYM128 12642.1 D 5.0984.34E−03 62 LYM90 12392.1 D 7.586 1.12E−02 68.6 LYM128 12641.3 D 4.1761.25E−02 32.7 LYM52 12894.8 D 8.228 1.31E−02 82.9 LYM203 12663.2 D 4.2667.47E−02 35.6 LYM107 12633.4 D 8.644 1.42E−02 92.2 CONTROL — D 3.146 — 0LYM90 12395.3 D 7.12 1.67E−02 58.3 LYM128 12641.3 E 0.447 9.19E−04 33LYM157 13341.4 D 7.114 1.98E−02 58.2 LYM128 12641.5 E 0.433 3.42E−0328.7 LYM68 11941.4 D 6.663 2.04E−02 48.1 LYM128 12642.1 E 0.44 4.86E−0330.8 LYM117 13624.7 D 5.482 2.19E−02 21.9 LYM203 12663.2 E 0.4132.97E−02 22.8 LYM68 11941.3 D 5.578 2.27E−02 24 LYM203 12662.2 E 0.4043.66E−02 20.3 LYM157 13341.1 D 7.026 2.67E−02 56.2 LYM128 12641.1 E0.414 8.08E−02 23.3 LYM248 13501.6 D 6.809 3.00E−02 51.4 CONTROL — E0.336 — 0 LYM117 13621.8 D 5.703 4.86E−02 26.8 LYM128 12642.1 F 6.0128.60E−05 45.8 LYM52 12894.7 D 6.314 5.92E−02 40.4 LYM128 12641.3 F 5.4791.32E−04 32.9 LYM157 13341.3 D 8.092 7.45E−02 79.9 LYM203 12663.2 F 5.077.26E−03 23 LYM213 12841.7 D 6.062 8.34E−02 34.8 LYM203 12664.1 F 4.6997.69E−03 14 LYM180 13443.7 D 5.259 8.41E−02 16.9 LYM203 12662.2 F 5.0411.20E−02 22.3 LYM157 13342.4 D 6.143 8.49E−02 36.6 LYM128 12641.5 F4.686 1.21E−02 13.7 CONTROL — D 4.498 — 0 LYM175 12651.4 F 4.8021.96E−02 16.5 LYM68 11941.4 E 0.616 1.55E−03 41.7 LYM107 12632.3 F 4.5733.01E−02 10.9 LYM107 12631.1 E 0.598 3.20E−03 37.5 LYM107 12631.2 F5.325 7.35E−02 29.1 LYM68 11942.2 E 0.593 4.66E−03 36.4 LYM128 12641.1 F5.151 7.83E−02 24.9 LYM52 12894.6 E 0.596 4.93E−03 37.2 CONTROL — F4.123 — 0 LYM248 13503.5 E 0.588 5.03E−03 35.2 LYM107 12632.1 G 0.5251.77E−03 47.2 LYM90 12393.1 E 0.587 5.49E−03 34.9 LYM128 12642.1 G 0.5682.05E−03 59.3 LYM52 12895.7 E 0.586 5.79E−03 34.7 LYM128 12641.3 G 0.5194.67E−03 45.3 LYM68 11941.3 E 0.586 6.68E−03 34.7 LYM203 12663.2 G 0.5831.40E−02 63.4 LYM52 12894.8 E 0.579 9.24E−03 33.1 LYM107 12631.1 G 0.4474.06E−02 25.4 LYM90 12394.2 E 0.569 1.49E−02 30.9 LYM175 12651.2 G 0.5685.89E−02 59.1 LYM157 13341.3 E 0.554 2.88E−02 27.3 LYM203 12662.2 G0.609 5.96E−02 70.7 LYM213 12841.6 E 0.553 2.96E−02 27.1 CONTROL — G0.357 — 0 LYM248 13501.6 E 0.558 3.17E−02 28.3 LYM128 12642.1 H 0.0574.93E−03 57.5 LYM107 12633.4 E 0.546 4.23E−02 25.5 LYM203 12663.2 H0.056 9.28E−03 55.3 LYM157 13341.1 E 0.545 4.29E−02 25.2 LYM203 12662.2H 0.06 1.20E−02 65 LYM180 13441.7 E 0.541 5.32E−02 24.4 LYM128 12641.3 H0.051 2.49E−02 40.3 LYM157 13341.4 E 0.54 5.93E−02 24.2 LYM175 12651.2 H0.056 2.52E−02 55.8 LYM107 12631.2 E 0.539 6.08E−02 24 LYM107 12632.1 H0.051 2.94E−02 40.3 LYM90 12392.1 E 0.533 8.04E−02 22.5 CONTROL — H0.036 — 0 LYM68 11942.3 E 0.526 9.63E−02 20.9 LYM224 13435.3 A 0.0070.00E+00 90.7 CONTROL — E 0.435 — 0 LYM217 13182.1 A 0.009 9.40E−05 160LYM107 12633.4 F 7.251 0.00E+00 30.4 LYM23 12783.5 A 0.007 6.40E−04 99LYM68 11942.2 F 7.607 0.00E+00 36.8 LYM164 12813.5 A 0.01 1.20E−03 169LYM90 12393.1 F 7.206 0.00E+00 29.6 LYM164 12813.8 A 0.009 2.03E−03143.6 LYM52 12894.8 F 6.932 3.00E−06 24.7 LYM251 13073.8 A 0.0073.58E−03 84.6 LYM157 13341.3 F 6.854 1.40E−05 23.3 LYM122 13712.3 A0.005 3.83E−03 45.5 LYM90 12394.2 F 6.941 1.40E−05 24.9 LYM274 13414.2 A0.009 4.46E−03 138.1 LYM68 11941.3 F 7.082 7.00E−05 27.4 LYM217 13181.11 A 0.009 4.68E−03 136.7 LYM180 13441.5 F 6.596 8.70E−05 18.6LYM79 13132.2 A 0.01 6.39E−03 166.9 LYM157 13341.4 F 6.805 1.05E−04 22.4LYM273 13721.3 A 0.011 7.17E−03 201.2 LYM248 13503.5 F 7.13 1.31E−0428.3 LYM273 13721.1 A 0.007 8.18E−03 81.8 LYM52 12895.7 F 6.936 2.60E−0424.8 LYM249 13631.1 A 0.006 8.20E−03 64.7 LYM90 12395.3 F 6.747 7.99E−0421.4 LYM23 12783.7 A 0.01 8.56E−03 162.1 LYM107 12631.1 F 6.89 9.89E−0423.9 LYM122 13713.2 A 0.007 8.63E−03 80.4 LYM180 13443.7 F 6.9341.01E−03 24.7 LYM249 13633.1 A 0.01 9.46E−03 172.4 LYM52 12891.8 F 6.4861.57E−03 16.7 LYM193 13484.3 A 0.008 9.51E−03 127.8 LYM248 13501.6 F7.256 2.13E−03 30.5 LYM245 13061.6 A 0.007 1.45E−02 82.5 LYM213 12841.6F 6.736 3.86E−03 21.2 LYM273 13722.4 A 0.007 1.60E−02 90.1 LYM15713341.1 F 6.312 3.94E−03 13.6 LYM251 13072.8 A 0.009 1.70E−02 138.1LYM90 12395.1 F 6.796 4.94E−03 22.2 LYM217 13181.7 A 0.006 1.82E−02 53LYM107 12631.2 F 6.846 6.89E−03 23.2 LYM23 12782.6 A 0.008 2.17E−02114.8 LYM248 13502.7 F 6.673 6.91E−03 20 LYM122 13714.4 A 0.01 2.25E−02166.2 LYM157 13342.4 F 6.442 7.43E−03 15.9 LYM245 13062.5 A 0.0082.38E−02 131.2 LYM107 12631.4 F 6.959 8.62E−03 25.2 LYM79 13133.1 A0.006 3.11E−02 62.6 LYM52 12894.6 F 7.328 1.06E−02 31.8 LYM23 12784.6 A0.007 4.14E−02 95.5 LYM68 11941.4 F 6.937 1.08E−02 24.8 LYM251 13073.7 A0.008 4.14E−02 126.4 LYM68 11942.3 F 6.771 1.09E−02 21.8 LYM273 13723.1A 0.008 4.80E−02 123 LYM117 13621.8 F 6.431 1.47E−02 15.7 LYM224 13434.2A 0.006 4.97E−02 59.9 LYM180 13442.6 F 6.003 1.85E−02 8 LYM251 13074.6 A0.005 5.26E−02 49.6 LYM213 12842.8 F 6.001 1.91E−02 7.9 LYM274 13413.4 A0.006 5.58E−02 76.3 LYM180 13441.7 F 6.814 2.38E−02 22.6 LYM273 13722.3A 0.007 6.00E−02 80.4 LYM90 12392.1 F 6.518 3.57E−02 17.2 LYM224 13435.1A 0.01 6.64E−02 177.9 LYM52 12894.7 F 6.232 5.88E−02 12.1 LYM217 13183.2A 0.009 6.68E−02 156.6 LYM213 12841.7 F 6.429 9.76E−02 15.6 LYM21713181.6 A 0.006 6.76E−02 62.6 CONTROL — F 5.559 — 0 LYM79 13133.3 A0.005 6.76E−02 41.3 LYM68 11942.2 G 0.719 1.00E−06 54.5 LYM23 12783.8 A0.005 7.66E−02 30.4 LYM90 12395.3 G 0.724 1.00E−06 55.5 LYM122 13714.2 A0.008 7.70E−02 114.8 LYM117 13623.9 G 0.586 5.20E−05 25.8 LYM249 13631.2A 0.007 8.25E−02 105.1 LYM248 13501.6 G 0.719 6.60E−05 54.4 LYM27413415.2 A 0.007 8.30E−02 83.2 LYM117 13622.6 G 0.709 5.32E−04 52.2LYM249 13631.4 A 0.005 8.68E−02 31.7 LYM107 12631.4 G 0.733 5.34E−0457.3 LYM251 13072.6 A 0.009 9.27E−02 159.3 LYM180 13441.7 G 0.6641.17E−03 42.6 LYM240 12682.1 A 0.009 9.57E−02 148.4 LYM52 12891.8 G0.878 1.61E−03 88.5 CONTROL — A 0.004 — 0 LYM213 12841.6 G 1.0982.01E−03 135.7 LYM251 13073.8 B 0.145 7.17E−04 59.3 LYM68 11943.5 G0.653 2.34E−03 40.2 LYM164 12813.8 B 0.166 8.84E−04 82.4 LYM117 13621.8G 0.608 3.36E−03 30.6 LYM122 13712.3 B 0.122 8.94E−04 33.4 LYM90 12394.2G 0.644 3.68E−03 38.4 LYM217 13182.1 B 0.179 1.19E−03 96.3 LYM52 12894.6G 0.69 3.90E−03 48.2 LYM273 13721.3 B 0.221 1.26E−03 142.7 LYM15713341.1 G 0.804 3.92E−03 72.7 LYM249 13631.1 B 0.159 1.43E−03 74.6LYM107 12633.4 G 0.829 5.17E−03 78 LYM273 13721.1 B 0.132 1.54E−03 44.4LYM52 12895.7 G 0.786 1.65E−02 68.8 LYM193 13484.3 B 0.165 2.86E−03 80.7LYM52 12894.8 G 0.987 1.95E−02 111.9 LYM79 13132.2 B 0.2 3.59E−03 119.3LYM117 13624.7 G 0.592 2.59E−02 27.2 LYM217  13181.11 B 0.203 4.90E−03123.1 LYM213 12841.8 G 0.746 2.62E−02 60.2 LYM122 13714.4 B 0.2494.98E−03 172.7 LYM180 13441.5 G 0.632 2.70E−02 35.7 LYM273 13723.1 B0.165 8.86E−03 80.7 LYM117 13624.4 G 0.576 2.79E−02 23.6 LYM274 13411.2B 0.114 1.00E−02 24.9 LYM248 13502.7 G 0.685 2.84E−02 47.1 LYM27413414.2 B 0.189 1.01E−02 107.4 LYM107 12632.1 G 0.588 2.98E−02 26.3LYM249 13633.1 B 0.195 1.09E−02 114.2 LYM157 13341.4 G 0.882 3.13E−0289.4 LYM245 13062.5 B 0.197 1.37E−02 116.1 LYM68 11941.3 G 0.5735.05E−02 23 LYM274 13413.4 B 0.141 1.41E−02 54.1 LYM157 13341.3 G 0.8345.09E−02 79.2 LYM23 12783.7 B 0.204 1.57E−02 123.9 LYM107 12631.1 G0.688 5.95E−02 47.8 LYM224 13435.3 B 0.149 2.06E−02 63.9 LYM90 12392.1 G0.633 6.01E−02 35.9 LYM79 13134.3 B 0.14 2.13E−02 53.9 LYM157 13341.7 G0.717 8.11E−02 54 LYM251 13072.8 B 0.161 2.19E−02 76.5 LYM52 12894.7 G0.72 9.20E−02 54.6 LYM23 12783.8 B 0.131 2.26E−02 43.9 LYM213 12841.7 G0.698 9.67E−02 49.9 LYM164 12813.5 B 0.221 2.28E−02 142.7 CONTROL — G0.466 — 0 LYM23 12782.7 B 0.125 2.52E−02 36.8 LYM107 12633.4 H 0.0810.00E+00 83.3 LYM217 13181.7 B 0.124 3.28E−02 35.6 LYM107 12631.4 H0.078 0.00E+00 75.7 LYM23 12782.6 B 0.16 3.33E−02 76 LYM117 13622.6 H0.08 0.00E+00 79.3 LYM273 13722.3 B 0.148 4.38E−02 62.3 LYM157 13341.4 H0.092 0.00E+00 108 LYM122 13712.1 B 0.147 4.52E−02 61.4 LYM157 13341.1 H0.08 0.00E+00 80.9 LYM251 13072.6 B 0.231 4.55E−02 153.2 LYM213 12841.6H 0.111 0.00E+00 149.2 LYM251 13074.6 B 0.128 4.80E−02 40.5 LYM5212894.8 H 0.103 0.00E+00 131.6 LYM131 12791.5 B 0.136 5.54E−02 49.2LYM52 12891.8 H 0.093 0.00E+00 108.9 LYM240 12682.1 B 0.164 5.66E−0280.3 LYM52 12895.7 H 0.083 0.00E+00 87 LYM122 13713.2 B 0.146 5.87E−0260.6 LYM90 12395.3 H 0.076 0.00E+00 71 LYM23 12784.6 B 0.18 6.16E−0297.8 LYM68 11942.2 H 0.074 1.00E−06 67.4 LYM79 13133.3 B 0.131 6.29E−0243.3 LYM52 12894.6 H 0.075 2.00E−06 68.1 LYM122 13714.2 B 0.176 6.66E−0293.6 LYM157 13341.3 H 0.085 3.00E−06 92.7 LYM249 13631.2 B 0.1726.94E−02 88.8 LYM213 12841.8 H 0.074 1.70E−05 66.3 LYM224 13435.1 B0.225 7.12E−02 146.6 LYM248 13501.6 H 0.069 3.10E−05 56.2 LYM217 13183.2B 0.197 7.76E−02 115.6 LYM90 12394.2 H 0.068 3.80E−05 54.1 LYM23 12783.5B 0.162 8.12E−02 77.2 LYM107 12631.1 H 0.073 4.60E−05 65.3 LYM21713181.6 B 0.145 8.35E−02 59 LYM68 11943.5 H 0.069 6.60E−05 54.6 LYM4013732.1 B 0.143 8.41E−02 56.4 LYM52 12894.7 H 0.074 1.57E−04 66.8 LYM7913133.1 B 0.156 9.62E−02 20.9 LYM90 12392.1 H 0.068 2.75E−04 52.6 LYM27313722.4 B 0.14 9.64E−02 54 LYM213 12841.7 H 0.07 5.36E−04 58.5 CONTROL —B 0.091 — 0 LYM157 13341.7 H 0.07 7.79E−04 57.3 LYM122 13714.4 C 0.9050.00E+00 135.4 LYM117 13624.7 H 0.062 2.19E−03 39.2 LYM122 13713.2 C0.681 0.00E+00 77 LYM117 13624.4 H 0.06 4.46E−03 35.7 LYM131 12793.3 C0.663 0.00E+00 72.4 LYM248 13502.7 H 0.063 4.46E−03 41 LYM164 12813.5 C0.933 0.00E+00 142.7 LYM180 13441.7 H 0.06 4.78E−03 35 LYM193 13482.4 C0.745 0.00E+00 93.9 LYM117 13623.9 H 0.059 7.75E−03 31.9 LYM217 13181.6C 0.859 0.00E+00 123.4 LYM68 11941.4 H 0.06 9.46E−03 36.1 LYM23 12783.7C 0.78 0.00E+00 102.9 LYM180 13441.5 H 0.058 1.89E−02 30.4 LYM24513062.5 C 0.773 0.00E+00 101.1 LYM107 12632.1 H 0.057 1.94E−02 29.2LYM245 13061.6 C 0.646 0.00E+00 68 LYM90 12393.1 H 0.06 2.02E−02 36.1LYM249 13631.2 C 0.886 0.00E+00 130.4 LYM68 11941.3 H 0.057 2.16E−0229.1 LYM249 13633.1 C 0.844 0.00E+00 119.6 LYM157 13342.4 H 0.0592.17E−02 33.1 LYM251 13073.8 C 1.06 0.00E+00 175.7 LYM68 11942.3 H 0.0632.18E−02 42.3 LYM251 13073.7 C 0.918 0.00E+00 138.9 LYM180 13442.6 H0.057 3.88E−02 27.7 LYM251 13072.6 C 0.777 0.00E+00 102.2 LYM117 13621.8H 0.055 5.30E−02 24.2 LYM251 13072.8 C 0.77 0.00E+00 100.4 CONTROL — H0.044 — 0 LYM251 13074.6 C 0.755 0.00E+00 96.5 LYM268 12482.3 A 0.0046.00E−06 66.2 LYM273 13723.1 C 0.886 0.00E+00 130.5 LYM140 12261.2 A0.004 5.80E−05 59.4 LYM273 13721.3 C 0.755 0.00E+00 96.3 LYM162 12231.3A 0.006 7.40E−05 130.9 LYM273 13722.4 C 0.665 0.00E+00 73 LYM13 11774.1A 0.006 1.23E−04 132.9 LYM274 13414.2 C 0.855 0.00E+00 122.3 LYM14012261.1 A 0.005 2.00E−04 74.9 LYM274 13415.2 C 0.847 0.00E+00 120.2LYM134 12314.2 A 0.004 3.70E−04 68.1 LYM274 13413.4 C 0.824 0.00E+00114.4 LYM162 12234.3 A 0.008 7.16E−04 204.3 LYM40 13734.2 C 0.6110.00E+00 58.9 LYM132 12271.4 A 0.005 8.37E−04 79.7 LYM79 13132.2 C 0.8110.00E+00 110.9 LYM140 12261.4 A 0.004 1.14E−03 47.8 LYM79 13133.1 C 0.710.00E+00 84.6 LYM289 12491.1 A 0.005 1.21E−03 110.6 LYM79 13134.3 C0.638 0.00E+00 66 LYM290 12504.1 A 0.004 2.88E−03 49.8 LYM249 13631.4 C0.594 1.00E−06 54.4 LYM290 12502.4 A 0.005 3.71E−03 101.9 LYM122 13712.3C 0.624 2.00E−06 62.3 LYM113 12444.4 A 0.005 3.73E−03 104.8 LYM27313722.3 C 0.65 2.00E−06 69.2 LYM140 12262.2 A 0.007 4.11E−03 187.9 LYM2312784.6 C 0.625 3.00E−06 62.5 LYM134 12312.4 A 0.006 5.01E−03 122.2LYM224 13435.1 C 0.691 4.00E−06 79.7 LYM268 12483.4 A 0.006 5.96E−03150.2 LYM249 13631.1 C 0.574 7.00E−06 49.3 LYM132 12275.3 A 0.0057.41E−03 73.9 LYM40 13732.1 C 0.728 1.00E−05 89.4 LYM268 12482.1 A 0.0091.25E−02 246.9 LYM79 13133.3 C 0.589 1.50E−05 53.1 LYM102 12222.3 A0.013 1.32E−02 387.9 LYM240 12682.1 C 0.898 1.80E−05 133.5 LYM3 12041.2A 0.005 1.33E−02 107.7 LYM131 12791.8 C 0.734 3.10E−05 90.9 LYM28912493.2 A 0.006 1.44E−02 144.4 LYM274 13413.1 C 0.617 4.50E−05 60.5 LYM312042.1 A 0.005 1.46E−02 108.7 LYM260 13095.7 C 0.586 7.10E−05 52.5LYM162 12234.4 A 0.005 1.69E−02 101 LYM23 12782.6 C 0.635 8.80E−05 65.2LYM113 12444.5 A 0.005 1.98E−02 96.1 LYM40 13732.2 C 0.57 1.08E−04 48.4LYM113 12442.2 A 0.005 2.39E−02 95.2 LYM260 13095.1 C 0.769 1.25E−04 100LYM289 12492.2 A 0.008 2.43E−02 194.7 LYM122 13712.1 C 0.594 1.35E−0454.4 LYM106 12142.1 A 0.009 2.45E−02 261.4 LYM164 12814.8 C 0.5652.55E−04 47 LYM113 12442.1 A 0.006 2.58E−02 136.7 LYM245 13064.8 C 0.5793.35E−04 50.6 LYM132 12273.2 A 0.003 2.75E−02 25.6 LYM122 13714.2 C0.618 3.64E−04 60.6 LYM134 12312.3 A 0.007 2.91E−02 155.1 LYM164 12814.7C 0.568 5.97E−04 47.6 LYM148 12173.1 A 0.006 2.96E−02 130 LYM224 13434.2C 0.545 8.91E−04 41.8 LYM13 11772.2 A 0.004 2.97E−02 36.2 LYM164 12813.8C 0.534 9.49E−04 38.8 LYM132 12276.1 A 0.008 3.01E−02 206.3 LYM22413435.5 C 0.554 1.23E−03 44 LYM129 12573.1 A 0.004 3.03E−02 71 LYM19313484.4 C 0.531 1.25E−03 38 LYM102 12222.1 A 0.012 3.89E−02 345.4 LYM2312783.8 C 0.515 1.59E−03 33.9 LYM134 12311.2 A 0.006 4.57E−02 122.2LYM193 13484.3 C 0.537 2.28E−03 39.7 LYM268 12481.1 A 0.004 5.25E−0272.9 LYM217 13182.1 C 0.544 3.30E−03 41.4 LYM10 11744.5 A 0.004 5.94E−0247.8 LYM249 13631.3 C 0.494 5.23E−03 28.5 LYM148 12172.1 A 0.0066.12E−02 116.4 LYM79 13134.2 C 0.504 8.40E−03 31.1 LYM113 12443.1 A0.008 6.54E−02 197.6 LYM273 13721.1 C 0.505 1.06E−02 31.4 LYM289 12491.4A 0.004 6.60E−02 52.7 LYM260 13095.8 C 0.497 1.36E−02 29.2 LYM10212222.2 A 0.008 7.00E−02 222.7 LYM23 12782.7 C 0.503 1.53E−02 30.9 LYM1011742.2 A 0.004 8.72E−02 44 LYM245 13061.8 C 0.483 1.73E−02 25.7 LYM1311772.1 A 0.005 9.00E−02 77.8 LYM23 12783.5 C 0.487 1.88E−02 26.7 LYM12912573.5 A 0.005 9.06E−02 85.5 LYM217 13181.7 C 0.479 3.48E−02 24.7LYM102 12221.1 A 0.007 9.14E−02 183.1 LYM224 13432.1 C 0.465 3.71E−02 21LYM106 12144.4 A 0.004 9.31E−02 66.2 CONTROL — C 0.384 — 0 LYM3 12043.2A 0.004 9.69E−02 70 LYM122 13713.2 D 6.388 0.00E+00 77 CONTROL — A 0.003— 0 LYM249 13631.4 D 5.398 0.00E+00 49.6 LYM13 11774.1 B 0.132 3.00E−0664.6 LYM273 13723.1 D 7.907 0.00E+00 119.1 LYM3 12041.2 B 0.134 2.20E−0466.7 LYM249 13631.3 D 4.599 3.10E−05 27.4 LYM162 12234.3 B 0.1864.15E−04 131.8 LYM249 13631.1 D 5.215 4.80E−05 44.5 LYM162 12234.4 B0.12 6.94E−04 49.1 LYM251 13073.8 D 9.276 2.48E−04 157 LYM140 12261.2 B0.103 8.53E−04 28 LYM131 12793.3 D 5.817 2.93E−04 61.2 LYM3 12043.2 B0.104 3.07E−03 29.9 LYM164 12813.5 D 8.334 4.25E−04 130.9 LYM290 12502.4B 0.13 3.23E−03 61.6 LYM245 13061.6 D 6.163 1.03E−03 70.8 LYM132 12276.1B 0.159 3.74E−03 98.1 LYM273 13722.4 D 5.997 1.03E−03 66.2 LYM16212231.3 B 0.136 5.97E−03 69.7 LYM23 12783.8 D 4.631 2.39E−03 28.3 LYM13412312.3 B 0.157 6.63E−03 95.2 LYM40 13734.2 D 5.446 2.86E−03 50.9 LYM28912491.1 B 0.128 7.98E−03 59 LYM217 13181.6 D 7.556 3.51E−03 109.4 LYM14012262.2 B 0.174 8.75E−03 117.3 LYM224 13432.1 D 4.165 4.08E−03 15.4LYM132 12275.3 B 0.114 8.82E−03 41.5 LYM274 13415.2 D 7.419 4.10E−03105.6 LYM289 12492.2 B 0.19 1.16E−02 137.4 LYM251 13074.6 D 6.6664.94E−03 84.7 LYM268 12482.1 B 0.192 1.21E−02 139.2 LYM249 13633.1 D 84.95E−03 121.7 LYM113 12442.1 B 0.145 1.30E−02 80.3 LYM23 12783.7 D7.137 6.65E−03 97.7 LYM268 12483.4 B 0.132 1.32E−02 64.2 LYM79 13134.3 D5.54 7.39E−03 53.5 LYM3 12042.1 B 0.142 1.38E−02 77.1 LYM122 13714.4 D8.315 8.23E−03 130.4 LYM290 12504.1 B 0.095 1.49E−02 17.8 LYM79 13133.1D 6.179 1.22E−02 71.2 LYM148 12173.1 B 0.141 1.51E−02 75.8 LYM79 13132.2D 7.315 1.42E−02 102.7 LYM134 12312.4 B 0.139 1.55E−02 73.1 LYM25113072.6 D 7.175 1.42E−02 98.8 LYM290 12502.1 B 0.096 1.59E−02 20 LYM25113073.7 D 8.23 1.56E−02 128 LYM106 12144.4 B 0.103 1.67E−02 28.3 LYM25113072.8 D 6.896 1.59E−02 91.1 LYM102 12222.3 B 0.252 2.42E−02 213.8LYM273 13721.3 D 6.844 1.74E−02 89.6 LYM148 12172.1 B 0.127 2.50E−0258.1 LYM274 13414.2 D 7.667 1.85E−02 112.4 LYM106 12142.1 B 0.1942.73E−02 141.6 LYM245 13062.5 D 6.543 2.21E−02 81.3 LYM102 12222.1 B0.237 3.04E−02 195.1 LYM40 13732.2 D 5.373 2.26E−02 48.9 LYM113 12444.5B 0.133 3.89E−02 65.3 LYM122 13712.3 D 5.384 2.45E−02 49.2 LYM12912573.5 B 0.135 3.90E−02 67.9 LYM224 13435.1 D 6.554 2.96E−02 81.6LYM129 12571.3 B 0.151 4.13E−02 88.4 LYM249 13631.2 D 7.72 3.46E−02113.9 LYM268 12482.3 B 0.094 4.38E−02 17.1 LYM273 13722.3 D 5.7773.61E−02 60.1 LYM113 12444.4 B 0.136 4.55E−02 69.1 LYM79 13133.3 D 5.1263.67E−02 42 LYM289 12493.2 B 0.13 4.69E−02 62.4 LYM23 12784.6 D 5.4283.91E−02 50.4 LYM113 12443.1 B 0.186 5.16E−02 131.8 LYM193 13482.4 D6.654 4.51E−02 84.4 LYM134 12311.2 B 0.139 5.91E−02 73.4 LYM193 13484.4D 4.895 4.61E−02 35.6 LYM132 12271.4 B 0.105 6.45E−02 31.3 LYM27413413.4 D 7.889 4.88E−02 118.6 LYM129 12573.1 B 0.114 6.88E−02 41.7LYM193 13481.2 D 4.14 5.04E−02 14.7 LYM140 12261.4 B 0.096 7.22E−02 19.9LYM40 13732.1 D 6.939 5.19E−02 92.3 LYM106 12141.4 B 0.121 7.36E−02 50.4LYM122 13712.1 D 5.608 5.71E−02 55.4 LYM102 12222.2 B 0.192 7.66E−02139.1 LYM164 12813.8 D 4.766 6.09E−02 32 LYM162 12233.2 B 0.114 8.96E−0242.5 LYM164 12814.8 D 5.126 6.17E−02 42 LYM140 12261.1 B 0.096 9.02E−0219.5 LYM240 12682.1 D 8.444 6.37E−02 134 LYM13 11772.2 B 0.131 9.05E−0263.5 LYM260 13095.7 D 5.147 6.73E−02 42.6 CONTROL — B 0.08 — 0 LYM27413413.1 D 5.528 7.60E−02 53.2 LYM102 12222.3 C 1.242 0.00E+00 203.7LYM23 12783.5 D 4.388 7.70E−02 21.6 LYM102 12222.1 C 1.148 0.00E+00180.7 LYM131 12791.8 D 6.882 8.02E−02 90.7 LYM106 12142.1 C 0.7440.00E+00 82.1 LYM193 13484.3 D 5.019 9.01E−02 39.1 LYM113 12444.4 C0.805 0.00E+00 96.9 CONTROL — D 3.609 — 0 LYM113 12443.1 C 0.7940.00E+00 94.1 LYM251 13073.8 E 0.584 1.00E−06 58.3 LYM129 12573.5 C0.861 0.00E+00 110.7 LYM251 13074.6 E 0.577 1.00E−06 56.3 LYM132 12276.1C 0.749 0.00E+00 83.3 LYM249 13631.2 E 0.582 4.00E−06 57.8 LYM14812173.1 C 0.798 0.00E+00 95.1 LYM164 12811.8 E 0.551 6.00E−06 49.2LYM148 12172.1 C 0.734 0.00E+00 79.5 LYM217 13181.6 E 0.567 1.50E−0553.6 LYM162 12234.3 C 0.978 0.00E+00 139.2 LYM245 13062.5 E 0.5373.50E−05 45.6 LYM162 12231.2 C 0.732 0.00E+00 79 LYM245 13064.8 E 0.5221.42E−04 41.5 LYM268 12482.3 C 0.784 0.00E+00 91.8 LYM122 13713.2 E0.522 2.35E−04 41.5 LYM268 12483.4 C 0.762 0.00E+00 86.3 LYM164 12813.5E 0.544 2.41E−04 47.5 LYM268 12483.2 C 0.74 0.00E+00 81 LYM122 13712.3 E0.519 2.99E−04 40.7 LYM289 12492.2 C 0.845 0.00E+00 106.7 LYM251 13073.7E 0.527 4.09E−04 42.7 LYM289 12491.1 C 0.789 0.00E+00 92.9 LYM27313722.4 E 0.505 9.21E−04 36.9 LYM289 12493.6 C 0.785 0.00E+00 92 LYM27313723.1 E 0.502 1.54E−03 36.1 LYM289 12493.2 C 0.721 0.00E+00 76.4 LYM2312783.7 E 0.493 2.29E−03 33.5 LYM290 12502.4 C 0.777 0.00E+00 90 LYM13112791.8 E 0.487 2.71E−03 31.9 LYM148 12173.5 C 0.711 1.00E−06 73.9LYM251 13072.8 E 0.498 2.78E−03 35 LYM268 12482.1 C 0.772 1.00E−06 88.9LYM260 13095.7 E 0.491 3.02E−03 32.9 LYM290 12501.2 C 0.724 1.00E−0677.1 LYM249 13631.1 E 0.489 3.23E−03 32.5 LYM129 12571.3 C 0.7762.00E−06 89.9 LYM249 13631.4 E 0.498 3.49E−03 34.8 LYM162 12231.3 C0.746 2.00E−06 82.5 LYM131 12793.3 E 0.486 3.59E−03 31.8 LYM102 12222.2C 0.748 5.00E−06 83.1 LYM251 13072.6 E 0.483 4.03E−03 31 LYM10 11744.5 C0.711 7.00E−06 73.8 LYM79 13132.2 E 0.478 5.43E−03 29.6 LYM134 12314.2 C0.658 2.30E−05 61 LYM79 13134.3 E 0.473 7.86E−03 28 LYM10 11741.4 C0.683 2.80E−05 67 LYM193 13482.4 E 0.478 8.17E−03 29.6 LYM113 12442.1 C0.648 3.30E−05 58.5 LYM79 13133.1 E 0.481 8.28E−03 30.4 LYM13 11774.1 C0.641 3.30E−05 56.7 LYM274 13415.2 E 0.475 9.01E−03 28.6 LYM134 12311.2C 0.651 7.30E−05 59.3 LYM40 13734.2 E 0.469 9.05E−03 27.2 LYM289 12491.4C 0.654 1.15E−04 60 LYM260 13095.1 E 0.496 1.32E−02 34.3 LYM148 12171.2C 0.608 1.49E−04 48.7 LYM224 13434.2 E 0.466 1.34E−02 26.4 LYM14012261.4 C 0.622 1.52E−04 52.1 LYM79 13133.3 E 0.465 1.55E−02 25.9 LYM13412312.4 C 0.616 1.68E−04 50.6 LYM164 12814.7 E 0.467 1.71E−02 26.5LYM148 12174.1 C 0.608 1.69E−04 48.6 LYM274 13413.4 E 0.475 2.10E−0228.6 LYM106 12142.2 C 0.647 2.21E−04 58.2 LYM40 13732.1 E 0.475 2.15E−0228.7 LYM268 12481.1 C 0.639 2.23E−04 56.3 LYM40 13732.2 E 0.46 2.66E−0224.6 LYM290 12502.1 C 0.61 4.18E−04 49.3 LYM260 13095.8 E 0.462 2.67E−0225.3 LYM290 12504.1 C 0.609 6.87E−04 48.9 LYM23 12784.6 E 0.453 2.97E−0222.8 LYM113 12444.5 C 0.596 7.01E−04 45.7 LYM274 13414.2 E 0.4572.97E−02 23.7 LYM102 12221.1 C 0.648 1.55E−03 58.5 LYM240 12682.1 E0.462 4.66E−02 25.1 LYM3 12042.1 C 0.57 2.95E−03 39.4 LYM23 12782.6 E0.451 5.25E−02 22.2 LYM129 12573.1 C 0.581 3.85E−03 42.1 LYM193 13481.2E 0.439 6.58E−02 18.9 LYM140 12262.3 C 0.574 4.08E−03 40.5 LYM23 12783.8E 0.438 8.19E−02 18.6 LYM134 12312.3 C 0.567 4.13E−03 38.6 LYM22413435.5 E 0.438 8.43E−02 18.8 LYM10 11741.2 C 0.559 4.92E−03 36.8 LYM27313722.3 E 0.44 9.76E−02 19.3 LYM132 12273.2 C 0.563 5.24E−03 37.6CONTROL — E 0.369 — 0 LYM290 12501.3 C 0.552 5.82E−03 34.9 LYM13112791.8 F 6.809 0.00E+00 41.1 LYM106 12141.4 C 0.577 7.47E−03 41.2LYM251 13073.8 F 7.178 0.00E+00 48.8 LYM140 12261.1 C 0.54 1.12E−02 32.2LYM251 13074.6 F 7.042 0.00E+00 46 LYM3 12041.1 C 0.547 1.19E−02 33.7LYM251 13073.7 F 6.988 0.00E+00 44.9 LYM132 12271.4 C 0.565 1.23E−0238.3 LYM251 13072.6 F 6.465 0.00E+00 34 LYM10 11742.2 C 0.569 1.23E−0239.3 LYM40 13734.2 F 5.902 0.00E+00 22.3 LYM140 12262.2 C 0.56 1.42E−0236.9 LYM249 13631.3 F 5.617 1.00E−06 16.4 LYM13 11772.1 C 0.53 1.46E−0229.6 LYM164 12811.8 F 5.941 2.00E−06 23.1 LYM3 12041.2 C 0.524 2.55E−0228.1 LYM79 13134.3 F 5.852 2.00E−06 21.3 LYM129 12572.2 C 0.521 3.13E−0227.5 LYM245 13064.8 F 6.215 3.00E−06 28.8 LYM102 12222.6 C 0.5223.24E−02 27.7 LYM274 13415.2 F 6.454 1.40E−05 33.8 LYM13 11772.2 C 0.5164.80E−02 26.2 LYM274 13413.4 F 6.963 4.00E−05 44.3 LYM132 12275.1 C0.501 6.79E−02 22.6 LYM193 13481.2 F 5.96 8.50E−05 23.5 LYM162 12234.4 C0.501 6.95E−02 22.5 LYM79 13132.2 F 6.122 1.83E−04 26.9 LYM13 11771.6 C0.519 7.56E−02 26.9 LYM122 13714.4 F 6.254 3.39E−04 29.6 LYM140 12261.2C 0.502 8.74E−02 22.7 LYM122 13712.1 F 6.19 3.43E−04 28.3 LYM3 12043.2 C0.494 9.78E−02 20.9 LYM245 13062.5 F 5.768 3.71E−04 19.6 CONTROL — C0.409 — 0 LYM249 13631.2 F 6.987 4.32E−04 44.8 LYM268 12482.3 D 6.5160.00E+00 87.6 LYM193 13482.4 F 6.308 4.55E−04 30.8 LYM268 12483.4 D6.288 2.00E−06 81 LYM217 13181.6 F 6.753 5.78E−04 40 LYM148 12171.2 D5.189 4.00E−05 49.4 LYM164 12814.8 F 5.561 7.94E−04 15.3 LYM289 12492.2D 7.223 7.40E−05 107.9 LYM131 12793.3 F 6.003 1.10E−03 24.4 LYM14812174.1 D 5.096 9.60E−05 46.7 LYM23 12783.7 F 6.275 1.34E−03 30.1 LYM14012261.1 D 4.512 3.53E−04 29.9 LYM122 13713.2 F 6.765 1.65E−03 40.2 LYM1311772.1 D 4.467 8.33E−04 28.6 LYM245 13061.6 F 6.117 3.30E−03 26.8LYM148 12173.1 D 6.767 1.30E−03 94.8 LYM273 13722.4 F 6.089 3.52E−0326.2 LYM290 12502.4 D 6.425 2.00E−03 85 LYM164 12813.5 F 6.915 5.03E−0343.3 LYM162 12234.3 D 8.82 2.51E−03 153.9 LYM249 13631.1 F 5.83 5.49E−0320.8 LYM162 12231.2 D 6.026 2.51E−03 73.5 LYM273 13723.1 F 6.3035.56E−03 30.6 LYM289 12493.6 D 6.413 2.68E−03 84.6 LYM40 13732.1 F 6.4466.08E−03 33.6 LYM289 12493.2 D 5.997 3.69E−03 72.6 LYM224 13435.1 F6.001 6.99E−03 24.4 LYM132 12276.1 D 6.257 4.48E−03 80.1 LYM240 12682.1F 6.594 9.82E−03 36.7 LYM113 12442.1 D 5.435 4.57E−03 56.5 LYM12213712.3 F 5.822 1.17E−02 20.7 LYM290 12501.3 D 4.573 5.64E−03 31.7LYM224 13435.5 F 5.726 1.24E−02 18.7 LYM13 11774.1 D 5.363 6.31E−03 54.4LYM249 13633.1 F 6.405 1.51E−02 32.8 LYM132 12275.3 D 4.076 6.87E−0317.3 LYM40 13732.2 F 6.015 1.52E−02 24.7 LYM148 12173.5 D 5.836 6.99E−0368 LYM274 13414.2 F 5.792 1.60E−02 20.1 LYM106 12142.1 D 6.279 7.68E−0380.8 LYM224 13432.1 F 5.184 1.77E−02 7.5 LYM113 12444.4 D 6.706 9.46E−0393 LYM249 13631.4 F 6.1 2.05E−02 26.4 LYM113 12444.5 D 4.965 1.05E−0242.9 LYM260 13095.7 F 5.943 2.05E−02 23.2 LYM102 12222.3 D 10.3471.06E−02 197.9 LYM260 13095.1 F 6.165 2.12E−02 27.8 LYM289 12491.1 D6.56 1.24E−02 88.8 LYM251 13072.8 F 5.901 2.20E−02 22.3 LYM113 12443.1 D6.784 1.25E−02 95.3 LYM164 12814.7 F 5.8 2.60E−02 20.2 LYM268 12483.2 D6.263 1.30E−02 80.3 LYM274 13413.1 F 5.834 2.70E−02 20.9 LYM134 12312.4D 5.224 1.38E−02 50.4 LYM193 13484.4 F 5.599 3.59E−02 16.1 LYM13412314.2 D 5.609 1.45E−02 61.5 LYM79 13133.1 F 5.782 4.30E−02 19.8 LYM14812172.1 D 6.055 1.59E−02 74.3 LYM273 13721.3 F 5.386 4.48E−02 11.6LYM140 12261.4 D 5.192 1.62E−02 49.5 LYM79 13133.3 F 5.452 4.87E−02 13LYM290 12501.2 D 6.097 1.82E−02 75.5 LYM23 12782.7 F 5.251 6.38E−02 8.8LYM129 12573.5 D 7.107 2.09E−02 104.6 LYM260 13095.8 F 5.588 9.86E−0215.8 LYM290 12502.1 D 5.038 2.88E−02 45 CONTROL — F 4.824 — 0 LYM312042.1 D 4.823 3.26E−02 38.8 LYM224 13435.3 G 0.764 0.00E+00 72.3LYM162 12231.3 D 6.434 3.53E−02 85.2 LYM40 13734.2 G 0.567 1.08E−04 27.9LYM134 12311.2 D 5.558 3.62E−02 60 LYM273 13722.4 G 0.856 4.09E−04 93.1LYM102 12222.1 D 9.506 3.77E−02 173.6 LYM273 13721.1 G 0.701 6.35E−0458.1 LYM129 12572.2 D 4.35 3.96E−02 25.2 LYM273 13721.3 G 1.063 7.82E−04139.6 LYM10 11741.4 D 5.712 4.08E−02 64.4 LYM122 13712.3 G 0.6328.84E−04 42.4 LYM129 12571.3 D 6.495 4.89E−02 87 LYM251 13073.8 G 0.8791.02E−03 98.3 LYM3 12043.2 D 4.152 5.04E−02 19.5 LYM23 12783.5 G 0.6631.60E−03 49.5 LYM10 11744.5 D 5.886 5.04E−02 69.4 LYM164 12813.5 G 0.8243.06E−03 85.8 LYM132 12275.1 D 4.228 5.06E−02 21.7 LYM249 13633.1 G0.944 3.80E−03 112.9 LYM10 11741.2 D 4.701 5.08E−02 35.3 LYM79 13132.2 G0.881 4.30E−03 98.7 LYM268 12482.1 D 6.36 5.11E−02 83.1 LYM217 13182.1 G0.797 5.62E−03 79.6 LYM134 12312.3 D 4.742 5.15E−02 36.5 LYM23 12783.7 G0.871 6.19E−03 96.5 LYM102 12222.2 D 6.476 5.30E−02 86.4 LYM193 13484.3G 0.77 7.00E−03 73.6 LYM268 12481.1 D 5.364 5.40E−02 54.4 LYM249 13631.1G 0.696 7.39E−03 56.9 LYM162 12234.4 D 4.154 5.73E−02 19.6 LYM25113072.8 G 0.807 8.13E−03 82 LYM290 12504.1 D 5.105 5.84E−02 47 LYM12213713.2 G 0.721 8.93E−03 62.6 LYM3 12041.1 D 4.538 6.02E−02 30.7 LYM27413414.2 G 0.895 1.25E−02 101.9 LYM132 12273.2 D 4.755 6.21E−02 36.9LYM224 13435.5 G 0.549 1.36E−02 23.7 LYM106 12142.2 D 5.335 6.22E−0253.6 LYM79 13133.3 G 0.652 1.38E−02 47.1 LYM289 12491.4 D 5.472 6.26E−0257.5 LYM217  13181.11 G 0.677 1.41E−02 52.7 LYM3 12041.2 D 4.4026.70E−02 26.7 LYM273 13723.1 G 0.825 1.50E−02 86 LYM102 12222.6 D 4.5188.47E−02 30.1 LYM122 13714.4 G 0.939 1.71E−02 111.7 LYM140 12262.3 D4.826 8.91E−02 38.9 LYM251 13073.7 G 0.964 1.78E−02 117.4 LYM129 12573.1D 4.888 9.60E−02 40.7 LYM274 13411.2 G 0.53 2.47E−02 19.6 CONTROL — D3.474 — 0 LYM245 13062.5 G 0.742 2.75E−02 67.4 LYM129 12573.5 E 0.7094.00E−06 62.2 LYM23 12782.6 G 0.794 2.84E−02 79.1 LYM289 12493.6 E 0.6977.00E−06 59.3 LYM274 13413.4 G 0.791 3.21E−02 78.4 LYM162 12231.2 E0.659 7.90E−05 50.8 LYM122 13712.1 G 0.695 3.25E−02 56.7 LYM102 12222.3E 0.675 8.60E−05 54.3 LYM245 13061.6 G 0.82 3.44E−02 84.9 LYM290 12502.4E 0.632 2.93E−04 44.5 LYM23 12784.6 G 0.752 3.82E−02 69.6 LYM148 12173.5E 0.625 5.90E−04 43 LYM251 13072.6 G 0.907 3.90E−02 104.5 LYM102 12222.1E 0.638 7.08E−04 46 LYM251 13074.6 G 0.643 3.93E−02 45.1 LYM290 12501.2E 0.622 7.15E−04 42.1 LYM40 13732.2 G 0.563 4.57E−02 27 LYM268 12482.3 E0.613 1.36E−03 40.2 LYM23 12782.7 G 0.541 4.89E−02 22 LYM10 11744.5 E0.607 1.97E−03 38.8 LYM217 13181.7 G 0.562 5.20E−02 26.7 LYM148 12172.1E 0.6 2.71E−03 37.1 LYM217 13183.2 G 0.913 5.21E−02 106 LYM148 12174.1 E0.591 3.47E−03 35.1 LYM164 12813.8 G 0.65 5.77E−02 46.5 LYM140 12261.4 E0.59 4.44E−03 34.9 LYM273 13722.3 G 0.639 5.87E−02 44.1 LYM268 12483.4 E0.595 4.63E−03 36.1 LYM224 13435.1 G 0.927 5.89E−02 108.9 LYM268 12483.2E 0.586 5.11E−03 34.1 LYM217 13181.6 G 0.622 6.07E−02 40.2 LYM11312443.1 E 0.58 7.96E−03 32.6 LYM274 13415.2 G 0.718 6.41E−02 61.8 LYM28912491.1 E 0.572 1.03E−02 30.8 LYM240 12682.1 G 0.808 6.42E−02 82.2LYM289 12492.2 E 0.582 1.07E−02 33.1 LYM79 13133.1 G 0.604 6.96E−02 36.2LYM132 12273.2 E 0.566 1.31E−02 29.5 LYM224 13434.2 G 0.643 7.21E−0244.9 LYM290 12501.3 E 0.566 1.39E−02 29.4 LYM122 13714.2 G 0.78 8.03E−0275.9 LYM106 12142.2 E 0.565 1.55E−02 29.3 LYM245 13064.8 G 0.5698.26E−02 28.3 LYM10 11742.2 E 0.568 1.60E−02 30 LYM40 13732.1 G 0.688.52E−02 53.3 LYM13 11774.1 E 0.562 1.77E−02 28.5 LYM249 13631.2 G 0.8048.60E−02 81.3 LYM113 12444.4 E 0.554 2.37E−02 26.7 LYM23 12783.8 G 0.58.97E−02 12.7 LYM134 12311.2 E 0.553 2.63E−02 26.4 LYM79 13134.3 G 0.5579.71E−02 25.7 LYM10 11741.4 E 0.554 2.69E−02 26.7 CONTROL — G 0.443 — 0LYM10 11741.2 E 0.548 3.19E−02 25.4 LYM122 13714.4 H 0.095 0.00E+00118.7 LYM132 12275.1 E 0.551 3.90E−02 26 LYM122 13713.2 H 0.072 0.00E+0066.2 LYM132 12276.1 E 0.55 3.90E−02 25.8 LYM122 13712.3 H 0.064 0.00E+0047 LYM290 12504.1 E 0.548 4.08E−02 25.2 LYM164 12813.5 H 0.08 0.00E+0084.1 LYM129 12571.3 E 0.549 4.67E−02 25.5 LYM193 13484.3 H 0.0730.00E+00 67 LYM289 12493.2 E 0.541 5.42E−02 23.7 LYM217 13183.2 H 0.0890.00E+00 104.8 LYM289 12491.4 E 0.543 5.79E−02 24.1 LYM217 13182.1 H0.084 0.00E+00 93 LYM113 12442.1 E 0.54 6.19E−02 23.4 LYM217  13181.11 H0.069 0.00E+00 58.8 LYM102 12222.2 E 0.541 6.54E−02 23.6 LYM224 13435.3H 0.07 0.00E+00 60.5 LYM134 12314.2 E 0.53 7.02E−02 21.2 LYM23 12783.7 H0.089 0.00E+00 104 LYM102 12222.6 E 0.524 9.02E−02 19.9 LYM23 12782.6 H0.082 0.00E+00 89 LYM140 12262.3 E 0.531 9.82E−02 21.4 LYM23 12784.6 H0.073 0.00E+00 68.3 CONTROL — E 0.437 — 0 LYM23 12783.5 H 0.066 0.00E+0051.8 LYM129 12573.5 F 7.529 0.00E+00 48.8 LYM245 13061.6 H 0.0810.00E+00 85.2 LYM148 12174.1 F 6.576 0.00E+00 30 LYM245 13062.5 H 0.0780.00E+00 79.4 LYM102 12222.6 F 6.331 1.00E−06 25.2 LYM249 13633.1 H0.098 0.00E+00 123.9 LYM134 12311.2 F 6.314 1.00E−06 24.8 LYM249 13631.1H 0.068 0.00E+00 56.9 LYM290 12502.4 F 6.934 3.00E−06 37.1 LYM25113073.7 H 0.097 0.00E+00 122.4 LYM132 12273.2 F 6.468 8.00E−06 27.9LYM251 13073.8 H 0.088 0.00E+00 102.1 LYM289 12491.1 F 6.657 2.20E−0531.6 LYM251 13072.6 H 0.087 0.00E+00 100.7 LYM290 12501.3 F 6.0594.00E−05 19.8 LYM251 13072.8 H 0.087 0.00E+00 99.1 LYM134 12314.2 F6.204 7.70E−05 22.6 LYM251 13074.6 H 0.068 0.00E+00 56.4 LYM148 12173.1F 6.77 1.40E−04 33.8 LYM273 13721.3 H 0.106 0.00E+00 143.3 LYM13 11774.1F 6.459 1.53E−04 27.7 LYM273 13723.1 H 0.089 0.00E+00 104 LYM290 12501.2F 6.823 1.66E−04 34.9 LYM273 13722.4 H 0.081 0.00E+00 85.6 LYM11312444.4 F 6.325 1.73E−04 25 LYM273 13721.1 H 0.074 0.00E+00 70.2 LYM1011744.5 F 7.044 1.83E−04 39.3 LYM273 13722.3 H 0.067 0.00E+00 54.8LYM268 12483.2 F 6.83 1.89E−04 35 LYM274 13414.2 H 0.094 0.00E+00 115.6LYM289 12492.2 F 6.926 2.40E−04 36.9 LYM274 13413.4 H 0.078 0.00E+0078.9 LYM289 12493.6 F 7.108 4.29E−04 40.5 LYM79 13132.2 H 0.095 0.00E+00117 LYM148 12172.1 F 6.754 6.38E−04 33.5 LYM79 13133.3 H 0.07 0.00E+0060.2 LYM268 12482.3 F 6.814 7.13E−04 34.7 LYM217 13181.6 H 0.0661.00E−06 51.9 LYM113 12443.1 F 6.925 9.38E−04 36.9 LYM249 13631.2 H0.085 1.00E−06 95.9 LYM140 12261.4 F 6.847 1.17E−03 35.4 LYM274 13415.2H 0.074 1.00E−06 69.9 LYM148 12173.5 F 6.568 1.48E−03 29.8 LYM79 13133.1H 0.064 1.00E−06 47.7 LYM113 12444.5 F 6.079 1.72E−03 20.2 LYM16412813.8 H 0.067 2.00E−06 54 LYM102 12222.1 F 7.226 2.12E−03 42.8 LYM22413435.1 H 0.089 2.00E−06 104.8 LYM10 11741.2 F 5.976 2.26E−03 18.1LYM240 12682.1 H 0.082 2.00E−06 89 LYM106 12142.2 F 6.158 2.57E−03 21.7LYM122 13714.2 H 0.077 5.00E−06 77.8 LYM162 12231.2 F 6.899 2.78E−0336.4 LYM40 13734.2 H 0.056 5.00E−06 28.3 LYM10 11741.4 F 6.128 3.19E−0321.2 LYM122 13712.1 H 0.063 1.70E−05 43.7 LYM148 12171.2 F 6.2764.06E−03 24.1 LYM224 13434.2 H 0.064 2.70E−05 47.3 LYM162 12234.3 F6.651 5.16E−03 31.5 LYM40 13732.1 H 0.068 3.00E−05 55.4 LYM268 12483.4 F6.746 5.50E−03 33.4 LYM217 13181.7 H 0.057 9.40E−05 31.2 LYM102 12222.3F 7.198 7.29E−03 42.3 LYM79 13134.3 H 0.057 1.09E−04 31.8 LYM289 12493.2F 6.305 7.70E−03 24.6 LYM260 13095.7 H 0.063 1.15E−04 45.5 LYM11312442.1 F 6.438 1.27E−02 27.3 LYM23 12782.7 H 0.056 1.57E−04 28 LYM10212222.2 F 6.677 1.28E−02 32 LYM40 13732.2 H 0.056 1.93E−04 28.4 LYM29012504.1 F 6.296 1.34E−02 24.5 LYM131 12791.5 H 0.06 3.33E−04 37.3 LYM13212275.1 F 6.322 1.46E−02 25 LYM245 13064.8 H 0.057 4.25E−04 29.9 LYM13212275.3 F 5.863 1.47E−02 15.9 LYM274 13411.2 H 0.053 6.16E−04 22.6LYM132 12276.1 F 6.536 1.48E−02 29.2 LYM79 13134.2 H 0.054 1.51E−03 24.6LYM106 12142.1 F 6.22 1.59E−02 23 LYM260 13095.1 H 0.07 2.31E−03 61.7LYM10 11742.2 F 6.226 1.66E−02 23.1 LYM23 12783.8 H 0.052 2.84E−03 18.8LYM106 12141.4 F 5.811 2.02E−02 14.9 LYM274 13413.1 H 0.055 9.12E−0325.3 LYM162 12231.3 F 6.508 2.18E−02 28.7 LYM249 13631.4 H 0.0519.60E−03 17.4 LYM129 12571.3 F 6.499 3.26E−02 28.5 LYM164 12814.8 H0.061 1.06E−02 39.9 LYM13 11772.2 F 6.13 3.39E−02 21.2 LYM224 13435.5 H0.05 1.25E−02 15.3 LYM132 12271.4 F 5.814 4.00E−02 14.9 LYM131 12791.8 H0.064 1.66E−02 47.4 LYM13 11772.1 F 5.743 6.50E−02 13.5 LYM193 13482.4 H0.055 2.52E−02 26.1 LYM129 12573.1 F 5.783 6.75E−02 14.3 LYM260 13095.8H 0.052 4.62E−02 19.8 LYM13 11773.2 F 5.505 6.85E−02 8.8 LYM224 13432.1H 0.049 4.71E−02 13 LYM3 12042.1 F 5.673 6.99E−02 12.1 CONTROL — H 0.044— 0 LYM268 12481.1 F 6.056 7.44E−02 19.7 LYM122 13711.3 A 0.011 1.00E−06231.7 LYM134 12312.4 F 6.028 9.99E−02 19.2 LYM234 14093.2 A 0.012.10E−05 192.5 CONTROL — F 5.058 — 0 LYM189 13315.2 A 0.01 5.08E−04197.1 LYM134 12312.4 G 0.704 0.00E+00 57.1 LYM217 13183.2 A 0.0085.11E−04 130.3 LYM140 12261.2 G 0.636 0.00E+00 42 LYM189 13314.5 A 0.0059.45E−04 67.4 LYM162 12234.3 G 0.912 1.00E−06 103.5 LYM79 13134.3 A0.005 9.97E−04 62 LYM290 12502.4 G 0.667 1.30E−05 48.9 LYM161 13233.5 A0.007 1.28E−03 124.2 LYM162 12234.4 G 0.75 5.67E−04 67.5 LYM217 13186.1A 0.012 1.32E−03 275.4 LYM140 12262.2 G 0.903 6.14E−04 101.7 LYM21713181.9 A 0.008 1.81E−03 134.2 LYM132 12276.1 G 0.821 1.92E−03 83.4LYM32 13964.1 A 0.008 2.09E−03 144.9 LYM140 12261.4 G 0.543 2.25E−0321.2 LYM234 14092.5 A 0.012 2.20E−03 277 LYM13 11772.2 G 0.634 3.99E−0341.6 LYM240 12683.5 A 0.01 2.37E−03 192.5 LYM289 12492.2 G 0.88 4.21E−0396.5 LYM219 13332.9 A 0.011 3.78E−03 233.2 LYM132 12271.4 G 0.6094.24E−03 36 LYM278 13364.5 A 0.004 3.79E−03 24.4 LYM289 12491.1 G 0.6915.40E−03 54.3 LYM245 13061.8 A 0.013 3.90E−03 306.9 LYM268 12482.1 G0.936 6.27E−03 108.9 LYM234 14092.1 A 0.005 5.44E−03 42 LYM3 12041.2 G0.661 6.62E−03 47.6 LYM74 13954.1 A 0.014 8.73E−03 315.4 LYM162 12231.3G 0.748 7.40E−03 67 LYM74 13954.2 A 0.009 1.17E−02 175.6 LYM268 12483.4G 0.717 7.99E−03 60.2 LYM188 13244.6 A 0.005 1.21E−02 53.6 LYM29012504.1 G 0.562 8.97E−03 25.4 LYM189 13311.3 A 0.009 1.35E−02 186.4 LYM312043.2 G 0.635 9.85E−03 41.8 LYM189 13311.2 A 0.01 1.83E−02 194.8LYM148 12173.1 G 0.849 1.05E−02 89.5 LYM274 13415.2 A 0.012 1.98E−02273.9 LYM13 11774.1 G 0.789 1.16E−02 76.1 LYM79 13132.2 A 0.013 2.07E−02300 LYM140 12261.1 G 0.521 1.27E−02 16.3 LYM217 13182.1 A 0.012 2.10E−02269.3 LYM106 12142.1 G 0.919 1.37E−02 105.3 LYM240 12682.1 A 0.0122.22E−02 264.7 LYM134 12312.3 G 0.781 1.42E−02 74.4 LYM189 13315.1 A0.017 2.23E−02 422.8 LYM3 12042.1 G 0.693 2.41E−02 54.8 LYM188 13244.7 A0.006 2.61E−02 87.3 LYM113 12442.1 G 0.702 2.51E−02 56.8 LYM79 13133.2 A0.009 3.08E−02 161.8 LYM102 12222.3 G 1.04 2.56E−02 132.2 LYM79 13133.3A 0.009 3.18E−02 183.3 LYM113 12444.5 G 0.672 3.11E−02 50 LYM189 13314.4A 0.009 3.27E−02 167.9 LYM289 12493.2 G 0.747 3.12E−02 66.7 LYM18813244.4 A 0.01 3.40E−02 220.2 LYM129 12573.5 G 0.69 3.20E−02 54.1 LYM7913134.1 A 0.01 3.50E−02 194.8 LYM113 12444.4 G 0.647 3.21E−02 44.4LYM274 13413.1 A 0.009 3.63E−02 166.4 LYM134 12311.2 G 0.702 3.87E−0256.7 LYM234 14092.8 A 0.012 3.81E−02 268.5 LYM129 12573.1 G 0.5823.90E−02 30 LYM74 13952.2 A 0.009 3.97E−02 181 LYM132 12275.3 G 0.6143.97E−02 37 LYM32 13963.4 A 0.008 4.02E−02 151.8 LYM113 12443.1 G 0.8654.24E−02 93.2 LYM274 13413.4 A 0.009 4.20E−02 169.5 LYM102 12222.1 G1.124 4.88E−02 151 LYM234 14091.1 A 0.008 4.79E−02 131.1 LYM106 12144.4G 0.638 5.62E−02 42.4 LYM161 13233.6 A 0.01 5.45E−02 220.9 LYM10212222.2 G 0.887 6.97E−02 98.1 LYM240 12683.9 A 0.004 5.60E−02 28.2LYM148 12172.1 G 0.649 7.46E−02 44.8 LYM79 13131.1 A 0.007 6.26E−02116.5 LYM102 12221.1 G 0.744 7.72E−02 66.1 LYM32 13963.1 A 0.0056.95E−02 49.7 LYM10 11744.5 G 0.556 8.52E−02 24.1 LYM273 13721.3 A 0.0067.08E−02 80.4 LYM290 12501.2 G 0.664 9.90E−02 48.2 LYM79 13134.2 A 0.0047.89E−02 32.8 CONTROL — G 0.448 — 0 LYM217 13181.6 A 0.005 8.18E−02 61.2LYM102 12222.1 H 0.118 0.00E+00 160.6 LYM122 13713.4 A 0.005 9.83E−0251.2 LYM102 12222.3 H 0.113 0.00E+00 149.3 CONTROL — A 0.003 — 0 LYM10612142.1 H 0.091 0.00E+00 101.4 LYM161 13233.5 B 0.146 0.00E+00 123.8LYM132 12276.1 H 0.084 0.00E+00 85.3 LYM189 13314.5 B 0.103 0.00E+0057.6 LYM140 12262.2 H 0.088 0.00E+00 94.1 LYM234 14093.2 B 0.1813.00E−06 177.1 LYM148 12173.1 H 0.084 0.00E+00 86.3 LYM32 13964.1 B0.145 5.12E−04 122.8 LYM162 12234.3 H 0.091 0.00E+00 100.3 LYM23414092.5 B 0.219 6.15E−04 235.5 LYM268 12482.1 H 0.094 0.00E+00 108.2LYM122 13711.3 B 0.225 6.83E−04 245.3 LYM289 12492.2 H 0.092 0.00E+00104 LYM240 12683.5 B 0.179 8.14E−04 173.6 LYM13 11774.1 H 0.079 1.00E−0674.4 LYM245 13061.8 B 0.24 1.32E−03 268.1 LYM162 12234.4 H 0.0743.00E−06 64.8 LYM217 13186.1 B 0.197 1.61E−03 202.2 LYM268 12483.4 H0.076 3.00E−06 68.5 LYM217 13183.2 B 0.144 1.66E−03 120.5 LYM134 12312.3H 0.077 4.00E−06 70 LYM189 13315.2 B 0.212 4.60E−03 224.4 LYM113 12443.1H 0.087 5.00E−06 91.5 LYM219 13332.9 B 0.194 5.69E−03 197.9 LYM16212231.3 H 0.074 8.00E−06 63.1 LYM74 13954.2 B 0.157 7.07E−03 141.3LYM290 12502.4 H 0.071 1.30E−05 57.2 LYM217 13182.1 B 0.231 7.34E−03253.5 LYM129 12573.5 H 0.075 2.20E−05 66.3 LYM234 14092.1 B 0.0877.90E−03 33 LYM134 12312.4 H 0.069 3.10E−05 52.5 LYM278 13364.5 B 0.0768.29E−03 17 LYM102 12222.2 H 0.087 7.00E−05 91.6 LYM74 13954.1 B 0.2488.32E−03 280 LYM289 12491.1 H 0.069 9.40E−05 53.2 LYM217 13181.9 B 0.1518.57E−03 130.7 LYM113 12444.4 H 0.071 1.12E−04 56.9 LYM189 13311.2 B0.174 8.79E−03 166.7 LYM134 12311.2 H 0.071 1.62E−04 57.5 LYM32 13963.4B 0.163 8.96E−03 149.3 LYM102 12221.1 H 0.076 2.25E−04 68.8 LYM24012683.9 B 0.077 9.39E−03 18.7 LYM289 12493.2 H 0.071 2.37E−04 57.5LYM189 13311.3 B 0.176 1.20E−02 169 LYM3 12042.1 H 0.068 4.18E−04 49.7LYM79 13134.1 B 0.173 1.36E−02 165.4 LYM113 12442.1 H 0.067 7.34E−0449.1 LYM79 13133.3 B 0.169 1.42E−02 158.3 LYM148 12172.1 H 0.0688.70E−04 50.9 LYM240 12682.1 B 0.202 1.49E−02 209.5 LYM129 12571.3 H0.07 1.22E−03 54.8 LYM79 13132.2 B 0.237 1.69E−02 262.6 LYM113 12444.5 H0.066 1.82E−03 45.3 LYM188 13244.7 B 0.116 1.77E−02 77.9 LYM290 12501.2H 0.068 1.94E−03 50 LYM188 13244.6 B 0.102 2.08E−02 56.2 LYM3 12041.2 H0.063 2.54E−03 38.7 LYM189 13315.1 B 0.281 2.09E−02 330 LYM140 12261.2 H0.061 4.70E−03 34.5 LYM79 13134.2 B 0.087 2.10E−02 33.3 LYM3 12043.2 H0.061 6.01E−03 35.8 LYM189 13314.4 B 0.158 2.19E−02 141.4 LYM132 12275.3H 0.061 9.29E−03 34.2 LYM188 13244.4 B 0.196 2.23E−02 200.6 LYM1311772.2 H 0.06 9.79E−03 32.3 LYM161 13233.6 B 0.185 2.28E−02 183.3LYM106 12141.4 H 0.063 1.25E−02 39.7 LYM274 13415.2 B 0.217 2.29E−02232.4 LYM106 12144.4 H 0.06 1.94E−02 32.6 LYM274 13413.4 B 0.1522.34E−02 133.3 LYM268 12481.1 H 0.061 2.01E−02 34.4 LYM234 14091.1 B0.149 2.38E−02 129 LYM134 12314.2 H 0.059 2.35E−02 29.9 LYM79 13133.2 B0.156 2.45E−02 139.7 LYM129 12573.1 H 0.057 3.09E−02 27.1 LYM79 13134.3B 0.109 2.50E−02 67.5 LYM132 12271.4 H 0.057 3.88E−02 25.2 LYM27313721.3 B 0.112 2.82E−02 71.3 LYM113 12442.2 H 0.059 3.90E−02 30 LYM27413413.1 B 0.167 3.18E−02 156.6 LYM10 11744.5 H 0.056 5.50E−02 24.8LYM217 13181.6 B 0.1 3.59E−02 53.3 LYM290 12504.1 H 0.056 5.52E−02 23LYM234 14092.8 B 0.208 3.90E−02 219.4 LYM129 12572.2 H 0.055 9.34E−0221.4 LYM32 13963.1 B 0.093 5.12E−02 42.1 LYM289 12491.4 H 0.056 9.88E−0223.2 LYM74 13952.2 B 0.154 5.75E−02 136.2 CONTROL — H 0.045 — 0 LYM7913131.1 B 0.152 6.99E−02 133.1 LYM248 13502.6 A 0.004 1.00E−05 49 LYM16113234.6 B 0.136 7.51E−02 108.5 LYM79 13134.7 A 0.004 6.75E−04 67 LYM21913334.8 B 0.114 7.99E−02 74.8 LYM157 13341.4 A 0.006 1.12E−03 127 LYM21913331.1 B 0.149 9.01E−02 127.7 LYM180 13442.7 A 0.004 1.29E−03 75CONTROL — B 0.065 — 0 LYM180 13442.6 A 0.004 2.39E−03 78 LYM122 13711.3C 0.947 0.00E+00 73.9 LYM52 12894.6 A 0.004 3.08E−03 50 LYM161 13233.6 C1.001 0.00E+00 83.9 LYM157 13341.1 A 0.007 3.26E−03 182 LYM189 13315.1 C1.281 0.00E+00 135.3 LYM79 13131.6 A 0.006 3.45E−03 146 LYM189 13315.2 C1.278 0.00E+00 134.6 LYM213 12842.8 A 0.009 5.95E−03 260 LYM189 13311.2C 1.043 0.00E+00 91.5 LYM157 13341.3 A 0.013 6.38E−03 420 LYM219 13332.9C 1.169 0.00E+00 114.6 LYM120 13382.2 A 0.007 1.08E−02 192 LYM23414092.5 C 1.196 0.00E+00 119.5 LYM213 12842.9 A 0.008 1.10E−02 235LYM240 12683.5 C 1.114 0.00E+00 104.6 LYM117 13624.7 A 0.004 1.29E−02 59LYM240 12682.1 C 1.053 0.00E+00 93.4 LYM79 13132.6 A 0.004 1.41E−02 64LYM274 13413.4 C 1.205 0.00E+00 121.3 LYM52 12895.7 A 0.009 1.45E−02 262LYM274 13415.2 C 1.108 0.00E+00 103.4 LYM107 12631.1 A 0.007 1.50E−02189 LYM32 13964.1 C 1.001 0.00E+00 83.9 LYM120 13382.8 A 0.007 1.53E−02160 LYM74 13954.1 C 1.346 0.00E+00 147.2 LYM120 13382.1 A 0.006 1.71E−02157 LYM74 13954.2 C 1.133 0.00E+00 108.1 LYM213 12841.8 A 0.005 1.96E−02114 LYM79 13132.2 C 1.066 0.00E+00 95.8 LYM227 14542.1 A 0.004 2.27E−0243 LYM79 13134.1 C 1.018 0.00E+00 86.9 LYM120 13382.3 A 0.008 2.67E−02225 LYM217 13181.6 C 0.974 1.00E−06 78.9 LYM52 12894.7 A 0.011 3.21E−02334 LYM245 13061.8 C 0.949 1.00E−06 74.3 LYM227 14544.2 A 0.004 3.26E−0253 LYM32 13963.4 C 0.949 2.00E−06 74.3 LYM52 12894.8 A 0.005 3.45E−02 88LYM188 13244.4 C 0.907 3.00E−06 66.6 LYM180 13441.7 A 0.009 3.65E−02 259LYM189 13311.3 C 0.923 3.00E−06 69.5 LYM248 13503.5 A 0.004 3.65E−02 75LYM234 14091.1 C 0.981 1.40E−05 80.1 LYM213 12841.6 A 0.006 3.85E−02 125LYM217 13186.1 C 0.889 1.90E−05 63.3 LYM107 12633.4 A 0.004 3.86E−02 71LYM234 14092.8 C 0.957 1.90E−05 75.7 LYM117 13622.6 A 0.004 3.99E−02 51LYM234 14093.2 C 0.872 3.90E−05 60.1 LYM227 14542.3 A 0.003 4.02E−02 37LYM79 13133.2 C 0.903 5.00E−05 65.8 LYM227 14542.5 A 0.003 4.55E−02 32LYM74 13952.2 C 0.95 1.17E−04 74.4 LYM120 13382.4 A 0.004 4.58E−02 59LYM161 13233.5 C 0.793 3.92E−04 45.6 LYM248 13504.6 A 0.003 4.71E−02 29LYM274 13413.1 C 0.919 7.62E−04 68.8 LYM52 12891.8 A 0.004 5.01E−02 62LYM219 13331.1 C 0.788 2.74E−03 44.8 LYM79 13131.5 A 0.004 5.09E−02 54LYM79 13131.1 C 0.825 3.08E−03 51.6 LYM107 12632.1 A 0.004 5.18E−02 55LYM240 12683.9 C 0.753 3.59E−03 38.2 LYM248 13502.7 A 0.003 5.65E−02 27LYM188 13244.7 C 0.767 4.32E−03 40.8 LYM117 13623.9 A 0.004 5.72E−02 63LYM161 13234.6 C 0.771 5.36E−03 41.5 LYM157 13342.4 A 0.003 6.07E−02 30LYM79 13133.3 C 0.765 9.03E−03 40.4 LYM117 13621.8 A 0.004 6.42E−02 41LYM189 13314.4 C 0.75 9.65E−03 37.7 LYM180 13441.5 A 0.007 9.29E−02 178LYM273 13721.3 C 0.706 2.08E−02 29.7 CONTROL — A 0.003 — 0 LYM79 13134.3C 0.708 2.18E−02 30 LYM79 13132.6 B 0.097 0.00E+00 57 LYM188 13244.6 C0.676 6.45E−02 24.2 LYM248 13502.6 B 0.084 3.80E−05 36.3 LYM234 14092.1C 0.66 8.67E−02 21.2 LYM52 12894.6 B 0.077 1.17E−03 24.1 LYM32 13963.1 C0.686 9.24E−02 26 LYM120 13382.8 B 0.143 1.23E−03 130.6 CONTROL — C0.545 — 0 LYM213 12842.8 B 0.197 1.73E−03 218 LYM32 13964.1 D 8.6510.00E+00 79.9 LYM157 13341.4 B 0.117 3.42E−03 88.4 LYM219 13332.9 D10.491 1.00E−05 118.2 LYM227 14544.2 B 0.093 4.06E−03 50.6 LYM12213711.3 D 8.611 5.80E−05 79.1 LYM120 13382.2 B 0.164 4.26E−03 164.9LYM161 13233.5 D 7.326 1.20E−04 52.3 LYM107 12633.4 B 0.102 4.42E−0365.5 LYM188 13244.4 D 8.097 2.06E−04 68.4 LYM52 12895.7 B 0.185 4.74E−03198.5 LYM234 14092.5 D 10.54 7.64E−04 119.2 LYM117 13621.8 B 0.0835.00E−03 33.8 LYM79 13132.2 D 9.36 3.54E−03 94.6 LYM180 13442.6 B 0.0955.31E−03 53.8 LYM74 13954.2 D 9.855 5.72E−03 104.9 LYM107 12631.1 B0.182 5.88E−03 193.5 LYM189 13315.2 D 10.946 5.76E−03 127.6 LYM24813504.6 B 0.08 6.04E−03 29.8 LYM74 13954.1 D 11.981 6.16E−03 149.1LYM157 13341.1 B 0.176 6.92E−03 183.8 LYM274 13413.4 D 10.317 7.08E−03114.5 LYM157 13341.3 B 0.289 8.30E−03 367.8 LYM161 13233.6 D 8.8698.43E−03 84.4 LYM120 13382.4 B 0.087 8.44E−03 41.4 LYM274 13415.2 D9.623 8.58E−03 100.1 LYM79 13131.6 B 0.153 9.73E−03 146.6 LYM245 13061.8D 8.368 8.65E−03 74 LYM117 13622.5 B 0.089 1.06E−02 44 LYM189 13315.1 D11.293 1.02E−02 134.8 LYM157 13342.4 B 0.092 1.14E−02 49 LYM234 14093.2D 7.632 1.08E−02 58.7 LYM120 13382.3 B 0.189 1.26E−02 205.1 LYM24012683.9 D 6.761 1.26E−02 40.6 LYM52 12891.8 B 0.099 1.29E−02 60.4 LYM18913311.3 D 8.149 1.49E−02 69.5 LYM227 14541.5 B 0.086 1.29E−02 39.2 LYM7913134.1 D 9.347 1.65E−02 94.4 LYM213 12842.9 B 0.183 1.30E−02 195.5LYM32 13963.4 D 8.288 1.66E−02 72.4 LYM180 13441.7 B 0.203 1.33E−02227.8 LYM240 12682.1 D 9.747 1.72E−02 102.7 LYM120 13382.1 B 0.1491.38E−02 140.6 LYM189 13311.2 D 8.99 1.94E−02 87 LYM213 12841.6 B 0.1251.59E−02 102.2 LYM79 13134.3 D 6.431 1.94E−02 33.7 LYM180 13442.7 B0.102 2.04E−02 64.6 LYM217 13186.1 D 7.5 1.95E−02 56 LYM52 12894.7 B0.237 2.09E−02 282.8 LYM217 13181.6 D 8.443 1.96E−02 75.6 LYM117 13622.6B 0.095 2.67E−02 53.3 LYM273 13721.3 D 6.132 3.30E−02 27.5 LYM21312841.8 B 0.118 2.79E−02 91.6 LYM234 14092.1 D 5.878 3.41E−02 22.2LYM248 13503.5 B 0.1 2.95E−02 62 LYM240 12683.5 D 9.957 3.82E−02 107.1LYM227 14542.1 B 0.096 4.16E−02 55.3 LYM79 13133.2 D 8.252 4.16E−02 71.6LYM213 12841.5 B 0.089 4.72E−02 43.5 LYM234 14091.1 D 8.586 5.33E−0278.5 LYM117 13623.9 B 0.089 4.77E−02 44.2 LYM234 14092.8 D 8.3735.62E−02 74.1 LYM248 13502.7 B 0.076 5.33E−02 23.7 LYM161 13234.6 D 7.157.26E−02 48.7 LYM107 12632.1 B 0.098 6.41E−02 57.9 LYM219 13331.1 D7.096 7.41E−02 47.6 LYM180 13441.5 B 0.162 6.47E−02 162.6 LYM188 13244.7D 6.69 8.77E−02 39.1 LYM227 14542.5 B 0.071 7.28E−02 15.4 CONTROL — D4.809 — 0 LYM52 12894.8 B 0.111 7.53E−02 79.6 LYM189 13315.2 E 0.6623.29E−03 29.1 LYM117 13624.7 B 0.082 7.84E−02 33 LYM274 13413.4 E 0.6461.08E−02 26.1 LYM248 13501.6 B 0.077 8.28E−02 24.4 LYM189 13315.1 E0.641 1.59E−02 25 CONTROL — B 0.062 — 0 LYM219 13332.9 E 0.613 4.07E−0219.6 LYM107 12631.1 C 0.831 0.00E+00 94.2 LYM161 13233.6 E 0.6027.90E−02 17.4 LYM120 13382.3 C 1.038 0.00E+00 142.4 LYM32 13964.1 E 0.67.97E−02 17 LYM157 13341.3 C 1.141 0.00E+00 166.5 CONTROL — E 0.513 — 0LYM157 13341.4 C 0.918 0.00E+00 114.5 LYM219 13332.9 F 7.586 1.00E−06 29LYM213 12842.8 C 1.035 0.00E+00 141.7 LYM32 13964.1 F 6.962 7.00E−0618.4 LYM52 12894.7 C 0.8 0.00E+00 86.9 LYM240 12682.1 F 6.843 3.90E−0516.4 LYM213 12842.9 C 0.762 1.00E−06 77.9 LYM74 13954.1 F 7.085 4.60E−0520.5 LYM120 13382.2 C 0.828 6.00E−06 93.3 LYM79 13134.1 F 7.2 1.08E−0322.5 LYM248 13503.5 C 0.741 6.00E−06 73 LYM274 13413.4 F 7.262 1.40E−0323.5 LYM52 12895.7 C 0.724 2.50E−05 69.1 LYM79 13132.2 F 6.662 1.94E−0313.3 LYM213 12841.6 C 0.7 3.20E−05 63.5 LYM189 13315.2 F 7.591 1.99E−0329.1 LYM120 13382.1 C 0.695 6.10E−05 62.3 LYM234 14092.5 F 7.1172.84E−03 21.1 LYM180 13441.7 C 0.763 8.30E−05 78.3 LYM189 13315.1 F7.396 2.91E−03 25.8 LYM180 13442.7 C 0.675 1.83E−04 57.6 LYM74 13954.2 F7.089 5.06E−03 20.6 LYM79 13131.5 C 0.68 2.64E−04 58.9 LYM161 13233.6 F6.978 1.61E−02 18.7 LYM157 13341.1 C 0.666 5.55E−04 55.6 LYM161 13233.5F 6.502 2.85E−02 10.6 LYM117 13621.8 C 0.659 8.30E−04 53.8 LYM12213711.3 F 6.643 3.74E−02 13 LYM79 13131.6 C 0.659 1.51E−03 53.9 LYM24012683.5 F 6.978 4.00E−02 18.7 LYM52 12894.8 C 0.67 1.78E−03 56.5 LYM7913134.3 F 6.403 5.79E−02 8.9 LYM52 12891.8 C 0.624 1.88E−03 45.8 LYM27413415.2 F 6.39 6.01E−02 8.7 LYM227 14542.3 C 0.647 2.21E−03 51.2 LYM24513061.8 F 6.366 7.89E−02 8.3 LYM157 13342.4 C 0.616 4.48E−03 43.8 LYM21713181.6 F 6.766 8.26E−02 15.1 LYM79 13132.6 C 0.605 4.76E−03 41.3CONTROL — F 5.879 — 0 LYM120 13382.8 C 0.607 5.79E−03 41.7 LYM18913315.2 G 1.284 1.90E−05 167.8 LYM180 13441.5 C 0.611 8.13E−03 42.7LYM217 13183.2 G 0.973 4.10E−05 103 LYM117 13622.6 C 0.593 8.16E−03 38.5LYM74 13954.2 G 0.931 6.30E−05 94.1 LYM248 13501.6 C 0.604 8.30E−03 41.1LYM234 14092.5 G 1.204 1.92E−04 151.1 LYM213 12841.5 C 0.594 9.39E−0338.7 LYM122 13711.3 G 1.159 3.08E−04 141.7 LYM227 14544.2 C 0.5931.48E−02 38.6 LYM240 12683.5 G 1.042 7.28E−04 117.2 LYM107 12631.2 C0.588 1.80E−02 37.4 LYM79 13134.3 G 0.808 1.09E−03 68.5 LYM117 13622.5 C0.604 1.90E−02 41 LYM245 13061.8 G 1.271 1.20E−03 165.1 LYM107 12633.4 C0.564 2.80E−02 31.8 LYM79 13132.2 G 1.32 1.33E−03 175.3 LYM52 12894.6 C0.548 4.99E−02 27.9 LYM234 14093.2 G 0.943 1.41E−03 96.7 LYM79 13134.7 C0.536 7.39E−02 25.2 LYM74 13954.1 G 1.313 1.81E−03 173.7 CONTROL — C0.428 — 0 LYM217 13186.1 G 0.911 1.88E−03 90.1 LYM157 13341.4 D 8.1010.00E+00 121.4 LYM32 13963.1 G 0.665 2.56E−03 38.7 LYM213 12842.9 D6.777 1.47E−04 85.2 LYM161 13233.6 G 1.064 2.90E−03 121.9 LYM213 12841.6D 6.039 2.00E−04 65 LYM217 13182.1 G 1.083 3.10E−03 125.8 LYM52 12894.7D 7.314 8.85E−04 99.9 LYM219 13332.9 G 1.063 4.10E−03 121.8 LYM11713622.6 D 5.113 1.50E−03 39.7 LYM161 13233.5 G 1.099 4.42E−03 129.2LYM107 12631.1 D 7.346 1.55E−03 100.8 LYM274 13415.2 G 1.15 4.92E−03139.8 LYM180 13442.7 D 6.266 1.64E−03 71.2 LYM274 13413.4 G 0.8996.80E−03 87.4 LYM120 13382.1 D 6.103 2.38E−03 66.8 LYM189 13315.1 G1.437 7.49E−03 199.8 LYM157 13341.3 D 9.886 2.61E−03 170.2 LYM18913311.2 G 1.029 7.55E−03 114.6 LYM52 12891.8 D 5.279 3.81E−03 44.3 LYM3213964.1 G 0.844 7.69E−03 76 LYM248 13503.5 D 6.501 4.31E−03 77.7 LYM7913134.1 G 0.99 1.05E−02 106.5 LYM107 12633.4 D 5.081 6.28E−03 38.9LYM234 14091.1 G 0.919 1.09E−02 91.6 LYM79 13132.6 D 5.272 7.18E−03 44.1LYM188 13244.4 G 1.049 1.17E−02 118.7 LYM79 13134.7 D 4.844 7.92E−0332.4 LYM217 13181.9 G 0.775 1.18E−02 61.6 LYM79 13131.5 D 5.961 1.41E−0262.9 LYM240 12683.9 G 0.579 1.27E−02 20.7 LYM52 12895.7 D 6.302 1.43E−0272.2 LYM189 13311.3 G 0.98 1.37E−02 104.4 LYM157 13341.1 D 6.1271.48E−02 67.4 LYM278 13364.5 G 0.574 1.37E−02 19.7 LYM213 12842.8 D9.745 1.57E−02 166.3 LYM240 12682.1 G 1.132 1.51E−02 136.1 LYM15713342.4 D 5.418 1.58E−02 48.1 LYM79 13133.3 G 0.974 1.51E−02 103.1LYM120 13382.8 D 5.233 2.06E−02 43 LYM234 14092.8 G 1.15 2.17E−02 139.7LYM120 13382.3 D 9.172 3.14E−02 150.7 LYM188 13244.6 G 0.58 2.18E−0220.9 LYM213 12841.5 D 5.044 3.32E−02 37.9 LYM79 13134.2 G 0.622 2.53E−0229.6 LYM117 13621.8 D 5.513 4.02E−02 50.7 LYM32 13963.4 G 0.967 2.55E−02101.8 LYM120 13382.2 D 7.207 4.05E−02 97 LYM79 13133.2 G 0.95 2.59E−0298 LYM79 13133.6 D 4.404 4.15E−02 20.4 LYM189 13314.5 G 0.604 2.68E−0226 LYM52 12894.6 D 4.637 4.35E−02 26.7 LYM161 13234.6 G 0.989 2.76E−02106.3 LYM248 13501.6 D 5.178 5.20E−02 41.5 LYM74 13952.2 G 0.8373.56E−02 74.5 LYM180 13441.5 D 5.621 5.27E−02 53.6 LYM189 13314.4 G0.803 3.63E−02 67.4 LYM180 13441.7 D 6.616 5.74E−02 80.8 LYM274 13413.1G 0.823 4.32E−02 71.6 LYM79 13131.6 D 5.672 6.56E−02 55 LYM79 13131.1 G0.941 5.88E−02 96.2 LYM227 14542.3 D 5.398 8.39E−02 47.5 LYM188 13244.7G 0.741 6.09E−02 54.5 CONTROL — D 3.659 — 0 LYM234 14092.1 G 0.6166.23E−02 28.6 LYM157 13341.3 E 0.563 8.32E−03 39.2 LYM219 13331.1 G0.778 8.27E−02 62.3 LYM248 13503.5 E 0.544 1.60E−02 34.6 CONTROL — G0.48 — 0 LYM248 13501.6 E 0.531 2.70E−02 31.5 LYM122 13711.3 H 0.1210.00E+00 155.6 LYM120 13382.2 E 0.522 4.43E−02 29.2 LYM161 13233.6 H0.112 0.00E+00 136 LYM120 13382.3 E 0.523 6.14E−02 29.4 LYM161 13233.5 H0.11 0.00E+00 133.1 LYM107 12631.1 E 0.511 6.15E−02 26.4 LYM161 13234.6H 0.105 0.00E+00 122 LYM120 13382.8 E 0.511 6.32E−02 26.4 LYM188 13244.4H 0.105 0.00E+00 121.6 LYM52 12891.8 E 0.498 9.65E−02 23.4 LYM18913315.1 H 0.146 0.00E+00 207.9 CONTROL — E 0.404 — 0 LYM189 13315.2 H0.133 0.00E+00 181.1 LYM107 12631.1 F 6.517 0.00E+00 32.4 LYM189 13311.2H 0.106 0.00E+00 123.6 LYM157 13341.4 F 6.663 0.00E+00 35.4 LYM18913311.3 H 0.099 0.00E+00 109.8 LYM79 13131.5 F 6.658 2.30E−05 35.3LYM217 13182.1 H 0.117 0.00E+00 146.7 LYM79 13132.6 F 6.269 6.80E−0527.4 LYM217 13183.2 H 0.096 0.00E+00 102.8 LYM248 13503.5 F 6.8497.40E−05 39.1 LYM217 13186.1 H 0.09 0.00E+00 91 LYM107 12633.4 F 6.421.94E−04 30.4 LYM219 13332.9 H 0.11 0.00E+00 132.5 LYM248 13501.6 F 6.552.54E−04 33.1 LYM234 14092.5 H 0.123 0.00E+00 160.3 LYM213 12842.8 F7.029 2.62E−04 42.8 LYM234 14092.8 H 0.119 0.00E+00 151.6 LYM180 13442.7F 6.274 3.41E−04 27.5 LYM234 14093.2 H 0.101 0.00E+00 113.6 LYM21312842.9 F 6.028 4.41E−04 22.4 LYM234 14091.1 H 0.094 0.00E+00 98.2LYM213 12841.6 F 5.836 5.41E−04 18.6 LYM240 12683.5 H 0.109 0.00E+00130.7 LYM120 13382.2 F 6.345 1.79E−03 28.9 LYM240 12682.1 H 0.1090.00E+00 130 LYM157 13341.1 F 5.677 2.64E−03 15.3 LYM245 13061.8 H 0.1280.00E+00 170.9 LYM157 13341.3 F 6.752 3.09E−03 37.2 LYM274 13415.2 H0.119 0.00E+00 152.5 LYM180 13441.7 F 5.935 3.68E−03 20.6 LYM274 13413.4H 0.095 0.00E+00 101.8 LYM180 13441.5 F 6.071 4.41E−03 23.3 LYM27413413.1 H 0.087 0.00E+00 84.2 LYM52 12894.7 F 6.008 5.17E−03 22.1 LYM3213963.4 H 0.102 0.00E+00 116.1 LYM120 13382.3 F 6.674 8.09E−03 35.6LYM32 13964.1 H 0.089 0.00E+00 87.8 LYM52 12891.8 F 5.774 9.79E−03 17.3LYM74 13954.1 H 0.128 0.00E+00 171.4 LYM79 13134.7 F 5.601 1.44E−02 13.8LYM74 13954.2 H 0.093 0.00E+00 96.9 LYM227 14542.3 F 5.91 1.57E−02 20.1LYM79 13132.2 H 0.134 0.00E+00 183.6 LYM79 13133.6 F 5.778 2.12E−02 17.4LYM79 13133.3 H 0.101 0.00E+00 114.2 LYM107 12631.2 F 5.764 2.69E−0217.1 LYM79 13134.1 H 0.1 0.00E+00 111.5 LYM120 13382.1 F 5.448 2.96E−0210.7 LYM79 13133.2 H 0.097 0.00E+00 104.7 LYM117 13621.8 F 5.5413.11E−02 12.6 LYM79 13134.3 H 0.082 0.00E+00 73.1 LYM117 13622.6 F 5.5783.16E−02 13.3 LYM189 13314.4 H 0.083 1.00E−06 75.5 LYM157 13342.4 F5.906 4.04E−02 20 LYM74 13952.2 H 0.085 1.00E−06 80.6 LYM52 12894.6 F5.686 5.87E−02 15.5 LYM79 13131.1 H 0.097 1.00E−06 104.4 LYM157 13341.1F 5.647 6.06E−02 14.7 LYM219 13331.1 H 0.082 1.20E−05 73.8 LYM12013382.8 F 5.597 7.48E−02 13.7 LYM188 13244.7 H 0.079 1.40E−05 66.2LYM248 13502.7 F 5.617 7.50E−02 14.1 LYM217 13181.9 H 0.071 7.40E−05 50CONTROL — F 4.923 — 0 LYM219 13334.8 H 0.075 4.81E−04 59.2 LYM79 13134.7G 0.783 0.00E+00 69 LYM32 13963.1 H 0.064 1.00E−03 34.7 LYM120 13382.8 G0.937 6.00E−06 102.4 LYM273 13721.3 H 0.067 1.42E−03 40.7 LYM180 13442.6G 0.708 1.72E−04 52.9 LYM189 13314.5 H 0.063 1.80E−03 33.5 LYM79 13132.6G 0.635 2.20E−04 37.1 LYM234 14092.1 H 0.064 2.49E−03 34.5 LYM24813502.6 G 0.6 3.71E−04 29.4 LYM217 13181.6 H 0.067 2.63E−03 41 LYM22714544.2 G 0.612 4.69E−04 32 LYM188 13244.6 H 0.062 3.19E−03 30.8 LYM10712633.4 G 0.695 6.12E−04 50.1 LYM219 13334.7 H 0.065 6.05E−03 37.1LYM120 13382.1 G 1.056 8.03E−04 128 LYM79 13134.2 H 0.061 6.73E−03 28.6LYM227 14542.1 G 0.625 8.16E−04 34.9 LYM240 12683.9 H 0.059 1.03E−0225.6 LYM117 13622.6 G 0.678 8.66E−04 46.3 LYM122 13713.4 H 0.0611.40E−02 29.1 LYM157 13341.1 G 1.038 1.08E−03 124.2 LYM278 13364.5 H0.058 2.02E−02 23.2 LYM157 13341.4 G 0.737 1.15E−03 59.1 LYM274 13413.3H 0.06 2.07E−02 27.2 LYM157 13341.3 G 1.528 1.56E−03 229.9 LYM24012684.8 H 0.059 5.27E−02 24.1 LYM120 13382.2 G 1.057 1.65E−03 128.2CONTROL — H 0.047 — 0 LYM107 12631.1 G 1.085 2.28E−03 134.2 LYM1 11603.2A 0.006 2.00E−06 74.1 LYM227 14541.5 G 0.61 2.98E−03 31.8 LYM1 11601.1 A0.007 1.20E−05 83.9 LYM120 13382.4 G 0.614 4.29E−03 32.6 LYM132 12275.3A 0.007 1.63E−04 96.5 LYM213 12842.8 G 1.205 4.34E−03 160.1 LYM17812164.2 A 0.006 2.14E−03 58 LYM248 13503.5 G 0.751 4.94E−03 62.2 LYM13212271.4 A 0.007 3.64E−03 97.2 LYM180 13442.7 G 0.839 5.84E−03 81.2 LYM111604.4 A 0.005 3.68E−03 29.4 LYM52 12895.7 G 1.044 6.49E−03 125.4LYM268 12483.2 A 0.008 6.62E−03 111.2 LYM157 13342.4 G 0.609 6.86E−0331.5 LYM5 12432.2 A 0.005 6.64E−03 28.7 LYM180 13441.5 G 1.027 7.31E−03121.8 LYM178 12164.3 A 0.011 1.01E−02 206.3 LYM213 12841.8 G 0.7327.99E−03 58 LYM134 12314.2 A 0.006 1.05E−02 77.6 LYM120 13382.3 G 1.0998.19E−03 137.3 LYM268 12482.3 A 0.006 1.08E−02 58.7 LYM52 12894.7 G1.153 8.28E−03 148.8 LYM129 12571.3 A 0.006 1.11E−02 54.5 LYM213 12842.9G 1.143 8.30E−03 146.8 LYM178 12163.3 A 0.011 1.16E−02 202.1 LYM7913131.6 G 1.11 8.39E−03 139.7 LYM1 11602.6 A 0.011 1.60E−02 197.2 LYM18013441.7 G 1.224 1.13E−02 164.3 LYM1 11602.1 A 0.005 1.79E−02 46.2 LYM15713341.1 G 0.527 1.68E−02 13.9 LYM268 12482.1 A 0.007 2.35E−02 97.9LYM227 14542.5 G 0.569 1.84E−02 22.7 LYM132 12276.1 A 0.009 2.60E−02146.9 LYM52 12894.6 G 0.525 1.93E−02 13.4 LYM129 12572.2 A 0.0052.65E−02 46.2 LYM52 12891.8 G 0.671 2.02E−02 44.8 LYM5 12432.1 A 0.0064.79E−02 70.6 LYM117 13621.8 G 0.57 2.22E−02 23 LYM6 11735.1 A 0.0065.37E−02 58 LYM213 12841.6 G 0.782 2.30E−02 68.9 LYM132 12273.2 A 0.0055.62E−02 44.1 LYM107 12632.1 G 0.648 2.97E−02 39.9 LYM268 12483.4 A0.006 6.34E−02 65 LYM117 13623.9 G 0.677 4.19E−02 46 LYM6 11736.1 A0.006 6.64E−02 71.3 LYM117 13624.7 G 0.695 5.21E−02 49.9 LYM6 11733.2 A0.004 6.75E−02 13.3 LYM117 13622.5 G 0.634 5.88E−02 36.9 LYM6 11735.2 A0.005 6.93E−02 49 LYM52 12894.8 G 0.73 6.31E−02 57.5 LYM134 12313.2 A0.011 7.63E−02 216.1 LYM79 13131.5 G 0.654 7.90E−02 41.2 LYM129 12573.5A 0.007 7.95E−02 102.8 CONTROL — G 0.463 — 0 CONTROL — A 0.004 — 0LYM107 12631.1 H 0.107 0.00E+00 141.1 LYM132 12275.3 B 0.134 1.00E−0686.1 LYM120 13382.3 H 0.111 0.00E+00 148.8 LYM1 11603.2 B 0.124 3.20E−0572.1 LYM120 13382.2 H 0.107 0.00E+00 139.8 LYM1 11601.1 B 0.123 4.10E−0571.4 LYM120 13382.1 H 0.102 0.00E+00 129.7 LYM132 12271.4 B 0.1241.69E−04 71.8 LYM120 13382.8 H 0.094 0.00E+00 111.3 LYM268 12483.2 B0.142 8.85E−04 96.8 LYM157 13341.3 H 0.146 0.00E+00 228.5 LYM178 12164.2B 0.111 2.98E−03 54.4 LYM157 13341.1 H 0.096 0.00E+00 117 LYM5 12432.2 B0.09 6.77E−03 25.1 LYM180 13441.7 H 0.114 0.00E+00 157.5 LYM134 12314.2B 0.138 7.76E−03 91.2 LYM180 13441.5 H 0.097 0.00E+00 119.2 LYM12912571.3 B 0.11 9.48E−03 52.8 LYM213 12842.8 H 0.114 0.00E+00 157 LYM111602.6 B 0.214 9.84E−03 197.7 LYM213 12842.9 H 0.107 0.00E+00 141.1LYM268 12482.3 B 0.124 1.45E−02 71.8 LYM52 12894.7 H 0.117 0.00E+00162.5 LYM268 12482.1 B 0.129 1.64E−02 78.6 LYM52 12895.7 H 0.1050.00E+00 136 LYM129 12572.2 B 0.101 1.69E−02 40.1 LYM79 13131.6 H 0.1080.00E+00 142.5 LYM129 12573.3 B 0.087 1.94E−02 21 LYM180 13442.7 H 0.081.00E−06 79.4 LYM6 11735.2 B 0.13 2.15E−02 80.5 LYM157 13341.4 H 0.0773.00E−06 73.4 LYM178 12164.3 B 0.215 2.21E−02 199.1 LYM213 12841.6 H0.077 1.70E−05 74.3 LYM178 12163.3 B 0.227 2.30E−02 214.8 LYM79 13134.7H 0.07 6.90E−05 57.7 LYM5 12432.1 B 0.116 2.54E−02 60.7 LYM52 12894.8 H0.075 1.89E−04 67.6 LYM6 11735.1 B 0.107 2.65E−02 48.9 LYM227 14544.2 H0.067 4.24E−04 49.8 LYM132 12276.1 B 0.18 2.72E−02 150.1 LYM107 12633.4H 0.066 5.81E−04 48.6 LYM134 12313.2 B 0.229 3.20E−02 217.6 LYM11713622.6 H 0.066 5.92E−04 49 LYM268 12483.4 B 0.128 4.11E−02 77.8 LYM24813503.5 H 0.067 7.50E−04 50.7 LYM134 12312.4 B 0.096 6.12E−02 33.5LYM213 12841.8 H 0.067 7.87E−04 50.6 LYM129 12573.5 B 0.144 6.28E−0299.7 LYM52 12891.8 H 0.067 9.77E−04 49.6 LYM6 11736.1 B 0.13 7.91E−0280.6 LYM117 13622.5 H 0.067 9.85E−04 51.7 LYM1 11604.4 B 0.083 9.90E−0216 LYM180 13442.6 H 0.065 1.09E−03 45.8 CONTROL — B 0.072 — 0 LYM11713623.9 H 0.064 3.89E−03 44.7 LYM1 11602.6 C 0.965 0.00E+00 91.4 LYM7913132.6 H 0.062 5.30E−03 38.5 LYM1 11601.1 C 0.83 8.30E−05 64.7 LYM10712632.1 H 0.063 5.57E−03 41.7 LYM268 12483.2 C 0.803 1.01E−04 59.3LYM120 13382.4 H 0.061 5.57E−03 38.2 LYM132 12276.1 C 0.936 1.06E−0485.8 LYM117 13624.7 H 0.064 5.91E−03 43.9 LYM178 12164.3 C 0.8311.49E−04 64.9 LYM248 13502.6 H 0.06 9.80E−03 35.3 LYM129 12571.3 C 0.7941.72E−04 57.5 LYM213 12841.5 H 0.062 1.07E−02 39 LYM129 12573.5 C 0.831.82E−04 64.6 LYM227 14542.1 H 0.059 1.46E−02 33.2 LYM268 12482.3 C0.752 4.97E−04 49.2 LYM157 13342.4 H 0.06 1.46E−02 34.4 LYM268 12483.4 C0.752 8.08E−04 49.2 LYM117 13621.8 H 0.06 1.51E−02 34.5 LYM178 12163.3 C0.849 8.09E−04 68.5 LYM79 13131.5 H 0.06 2.75E−02 35.8 LYM5 12435.1 C0.771 9.77E−04 52.9 LYM227 14541.5 H 0.057 3.75E−02 28.4 LYM134 12314.2C 0.733 1.55E−03 45.5 CONTROL — H 0.044 — 0 LYM178 12164.2 C 0.6797.95E−03 34.7 LYM79 13131.6 A 0.004 9.00E−06 63 LYM134 12313.2 C 0.7398.31E−03 46.6 LYM79 13133.6 A 0.004 1.55E−03 61 LYM132 12275.3 C 0.6751.62E−02 34 LYM79 13131.5 A 0.004 3.66E−02 40 LYM1 11603.2 C 0.6833.61E−02 35.6 LYM79 13132.6 A 0.004 3.91E−02 47 CONTROL — C 0.504 — 0LYM227 14544.2 A 0.004 5.01E−02 72 LYM1 11602.6 D 8.109 7.70E−05 79.7LYM79 13134.7 A 0.003 5.24E−02 39 LYM268 12483.2 D 6.779 9.34E−04 50.3LYM227 14542.5 A 0.003 7.71E−02 35 LYM268 12482.3 D 6.318 9.47E−04 40CONTROL — A 0.003 — 0 LYM129 12571.3 D 6.587 1.03E−03 46 LYM79 13133.6 B0.089 3.95E−03 23.5 LYM134 12314.2 D 6.146 2.72E−03 36.2 LYM227 14544.2B 0.101 1.09E−02 40.9 LYM1 11601.1 D 7.074 6.19E−03 56.8 LYM227 14542.1B 0.082 5.43E−02 14.7 LYM268 12483.4 D 6.375 1.10E−02 41.3 LYM79 13131.5B 0.093 7.88E−02 28.9 LYM178 12164.2 D 5.681 1.80E−02 25.9 LYM79 13132.6B 0.095 8.38E−02 32.4 LYM129 12573.5 D 7.105 1.84E−02 57.5 LYM22714542.5 B 0.085 9.81E−02 18.4 LYM178 12164.3 D 6.941 1.87E−02 53.8CONTROL — B 0.072 — 0 LYM132 12276.1 D 7.985 3.78E−02 77 LYM79 13134.7 C0.665 5.00E−05 49.9 LYM5 12435.1 D 6.433 4.32E−02 42.6 LYM79 13132.6 C0.683 1.75E−04 53.9 LYM132 12275.3 D 5.769 5.38E−02 27.9 LYM227 14544.2C 0.606 2.21E−03 36.6 LYM178 12163.3 D 7.171 6.48E−02 59 LYM79 13133.6 C0.614 5.09E−03 38.3 CONTROL — D 4.511 — 0 LYM79 13131.5 C 0.606 6.01E−0336.5 LYM178 12164.3 E 0.618 6.14E−04 35.8 LYM227 14542.5 C 0.5899.41E−03 32.9 LYM5 12435.1 E 0.6 6.85E−04 31.8 LYM79 13131.6 C 0.5592.18E−02 26 LYM134 12314.2 E 0.598 1.04E−03 31.5 LYM227 14542.3 C 0.5762.31E−02 29.9 LYM268 12482.3 E 0.59 1.49E−03 29.6 CONTROL — C 0.444 — 0LYM129 12571.3 E 0.596 1.76E−03 31 LYM79 13134.7 D 5.698 4.00E−06 47.8LYM132 12276.1 E 0.595 2.11E−03 30.8 LYM79 13131.6 D 5.051 2.55E−04 31LYM1 11602.6 E 0.58 4.57E−03 27.6 LYM227 14544.2 D 5.176 7.52E−03 34.3LYM132 12275.3 E 0.587 9.38E−03 29 LYM79 13131.5 D 5.504 5.52E−02 42.8LYM178 12164.2 E 0.557 1.30E−02 22.5 LYM79 13132.6 D 5.911 5.61E−02 53.3LYM268 12483.4 E 0.539 4.86E−02 18.5 LYM227 14542.5 D 5.159 6.06E−0233.8 LYM178 12163.3 E 0.553 5.88E−02 21.4 LYM79 13133.6 D 5.429 8.59E−0240.9 LYM1 11601.1 E 0.543 6.29E−02 19.2 CONTROL — D 3.855 — 0 LYM12912573.5 E 0.548 7.27E−02 20.4 LYM79 13134.7 F 6.191 5.25E−04 18 LYM512432.1 E 0.532 7.47E−02 16.9 LYM79 13132.6 F 6.158 6.45E−03 17.4 LYM12912572.2 E 0.52 7.70E−02 14.4 LYM79 13131.5 F 6.286 7.80E−03 19.8 CONTROL— E 0.455 — 0 LYM227 14542.3 F 5.863 7.80E−02 11.7 LYM268 12482.3 F6.797 1.32E−04 22.4 CONTROL — F 5.247 — 0 LYM5 12435.1 F 6.566 5.75E−0418.2 LYM79 13131.6 G 0.756 8.17E−03 48 LYM134 12314.2 F 6.858 2.92E−0323.5 LYM227 14544.2 G 0.575 3.56E−02 12.6 LYM132 12276.1 F 6.9684.43E−03 25.4 CONTROL — G 0.511 — 0 LYM129 12571.3 F 6.614 1.13E−02 19.1LYM79 13131.6 H 0.075 1.40E−05 50.2 LYM178 12164.3 F 6.685 1.23E−02 20.3LYM227 14544.2 H 0.062 1.36E−02 24.5 LYM268 12483.2 F 6.477 1.34E−0216.6 LYM79 13133.6 H 0.062 1.76E−02 25.2 LYM268 12483.4 F 6.494 1.43E−0216.9 LYM79 13131.5 H 0.064 2.54E−02 28.1 LYM1 11602.6 F 6.607 1.52E−0218.9 LYM227 14542.5 H 0.061 3.57E−02 22.1 LYM1 11601.1 F 6.595 2.97E−0218.7 LYM79 13134.7 H 0.059 6.68E−02 19.2 LYM178 12164.2 F 6.106 4.81E−029.9 LYM79 13132.6 H 0.059 8.94E−02 18.9 LYM132 12275.3 F 6.546 7.02E−0217.8 CONTROL — H 0.05 — 0 LYM129 12573.5 F 6.544 9.24E−02 17.8 CONTROL —F 5.555 — 0 LYM1 11601.1 G 0.75 8.00E−06 56.3 LYM132 12271.4 G 0.761.00E−05 58.3 LYM132 12275.3 G 0.841 4.10E−05 75.2 LYM268 12482.1 G0.738 2.75E−04 53.6 LYM178 12164.3 G 1.031 1.85E−03 114.7 LYM1 11603.2 G0.665 1.89E−03 38.5 LYM134 12314.2 G 0.759 2.43E−03 58.1 LYM1 11602.6 G1.002 3.24E−03 108.6 LYM178 12164.2 G 0.615 7.36E−03 28 LYM178 12163.3 G0.929 1.03E−02 93.6 LYM132 12276.1 G 0.833 1.10E−02 73.5 LYM6 11736.1 G0.75 1.25E−02 56.2 LYM129 12573.5 G 0.786 2.28E−02 63.6 LYM268 12483.2 G0.728 2.44E−02 51.6 LYM6 11735.2 G 0.594 2.79E−02 23.7 LYM268 12482.3 G0.63 3.55E−02 31.3 LYM5 12432.1 G 0.741 3.96E−02 54.3 LYM129 12572.2 G0.598 4.01E−02 24.5 LYM1 11602.1 G 0.588 5.84E−02 22.4 LYM268 12483.4 G0.708 6.03E−02 47.5 LYM134 12313.2 G 0.968 6.92E−02 101.5 CONTROL — G0.48 — 0 LYM136 13423.1 A 0.006 4.00E−06 156.7 LYM160 13472.1 A 0.010.00E+00 138.8 LYM1 11601.1 A 0.004 2.49E−04 69.1 LYM136 13423.4 A 0.0091.48E−04 118.5 LYM136 13421.5 A 0.006 1.77E−03 129.9 LYM293 13391.2 A0.007 5.51E−03 57.6 LYM84 13404.4 A 0.004 3.79E−03 81.4 LYM293 13391.4 A0.009 8.63E−03 106 LYM1 11602.6 A 0.007 5.63E−03 182.5 LYM136 13421.7 A0.008 1.58E−02 94 LYM1 11603.2 A 0.005 7.42E−03 125.8 LYM136 13421.8 A0.008 2.02E−02 92.2 LYM84 13401.2 A 0.005 1.15E−02 91.8 LYM160 13471.1 A0.008 3.06E−02 95.2 LYM84 13403.1 A 0.007 1.33E−02 170.1 LYM84 13403.1 A0.008 3.34E−02 90.4 LYM84 13403.3 A 0.005 1.48E−02 99 LYM160 13472.2 A0.007 3.80E−02 78.5 LYM136 13421.6 A 0.005 2.79E−02 116.5 LYM84 13403.3A 0.012 6.33E−02 186 LYM136 13421.8 A 0.007 2.82E−02 189.7 LYM29313392.2 A 0.007 6.99E−02 70.1 LYM84 13403.2 A 0.006 2.92E−02 156.7 LYM8413401.2 A 0.007 7.32E−02 66.6 LYM1 11602.1 A 0.004 3.31E−02 70.1 LYM29313391.9 A 0.007 7.86E−02 67.8 LYM136 13423.2 A 0.004 3.85E−02 79.4LYM136 13421.5 A 0.008 8.34E−02 99.4 LYM1 11604.4 A 0.003 5.00E−02 39.2LYM160 13471.4 A 0.006 9.24E−02 31.3 CONTROL — A 0.002 — 0 CONTROL — A0.004 — 0 LYM84 13401.2 B 0.093 1.52E−03 80.5 LYM160 13472.1 B 0.2185.01E−03 128.9 LYM1 11601.1 B 0.09 4.19E−03 75.6 LYM136 13423.4 B 0.197.33E−03 100 LYM136 13423.1 B 0.125 5.82E−03 143.9 LYM136 13421.8 B0.173 1.03E−02 81.6 LYM84 13403.3 B 0.1 6.00E−03 95.1 LYM293 13391.2 B0.138 1.09E−02 44.7 LYM136 13421.5 B 0.103 8.84E−03 100 LYM84 13401.2 B0.138 1.59E−02 44.7 LYM136 13421.6 B 0.123 9.57E−03 139 LYM136 13421.7 B0.153 2.38E−02 60.5 LYM1 11602.6 B 0.13 1.32E−02 153.7 LYM84 13403.3 B0.275 3.54E−02 189.5 LYM136 13423.2 B 0.088 1.41E−02 70.7 LYM160 13472.2B 0.155 6.63E−02 63.2 LYM136 13421.8 B 0.155 2.23E−02 202.4 LYM29313391.4 B 0.193 7.66E−02 102.6 LYM84 13403.2 B 0.155 2.32E−02 202.4LYM136 13421.5 B 0.18 8.25E−02 89.5 LYM84 13404.4 B 0.095 2.70E−02 85.4LYM160 13471.1 B 0.18 8.25E−02 89.5 LYM1 11603.2 B 0.10 2.70E−02 109.8LYM84 13403.1 B 0.195 8.89E−02 105.3 LYM1 11604.4 B 0.073 3.33E−02 41.5CONTROL — B 0.095 — 0 LYM1 11602.1 B 0.088 3.79E−02 70.7 LYM136 13421.5G 1.16 1.40E−05 113.3 LYM84 13403.1 B 0.15 5.94E−02 192.7 LYM160 13472.1G 1.073 1.70E−05 97.2 CONTROL — B 0.051 — 0 LYM160 13471.1 G 0.9731.00E−04 78.9 LYM1 11601.1 G 0.75 7.00E−06 88.7 LYM84 13403.1 G 0.9151.04E−04 68.3 LYM84 13403.1 G 0.75 8.00E−06 88.7 LYM136 13423.4 G 1.081.69E−03 98.6 LYM84 13404.4 G 0.64 9.30E−05 61 LYM136 13421.8 G 1.0353.80E−03 90.3 LYM1 11603.2 G 0.635 7.21E−04 59.7 LYM293 13391.4 G 1.1935.56E−03 119.3 LYM136 13421.6 G 0.688 1.51E−03 73 LYM84 13401.2 G 0.837.52E−03 52.6 LYM84 13401.2 G 0.688 2.17E−03 73 LYM84 13403.3 G 1.4187.77E−03 160.7 LYM1 11602.6 G 0.783 3.89E−03 96.9 LYM160 13472.2 G 0.761.94E−02 39.8 LYM136 13423.1 G 0.83 4.81E−03 108.8 LYM136 13421.7 G 0.882.80E−02 61.8 LYM84 13403.3 G 0.72 4.83E−03 81.1 LYM293 13391.2 G 0.744.83E−02 36.1 LYM136 13421.5 G 0.62 6.93E−03 56 LYM293 13392.2 G 0.8854.98E−02 62.8 LYM84 13403.2 G 0.785 1.19E−02 97.5 LYM136 13423.2 G 0.7958.04E−02 46.2 LYM136 13421.8 G 0.878 1.65E−02 120.8 LYM293 13391.9 G0.813 8.66E−02 49.4 LYM136 13423.2 G 0.61 2.94E−02 53.5 LYM160 13471.4 G0.725 9.93E−02 33.3 LYM1 11604.4 G 0.515 2.96E−02 29.6 CONTROL — G 0.544— 0 CONTROL — G 0.398 — 0 LYM136 13421.5 H 0.122 0.00E+00 119 LYM13613423.1 H 0.081 0.00E+00 101.6 LYM160 13472.1 H 0.118 0.00E+00 110.6LYM84 13403.1 H 0.076 0.00E+00 88.3 LYM84 13403.3 H 0.15 1.00E−06 168.9LYM1 11602.6 H 0.077 1.00E−06 91.4 LYM136 13423.4 H 0.116 3.00E−06 108.4LYM1 11601.1 H 0.068 2.00E−06 70.4 LYM293 13391.4 H 0.121 6.00E−06 116.8LYM84 13403.2 H 0.083 2.00E−06 107 LYM136 13421.8 H 0.106 7.20E−05 90.5LYM136 13421.8 H 0.087 4.00E−06 116.3 LYM160 13471.1 H 0.097 1.50E−0474.2 LYM136 13421.6 H 0.068 7.00E−06 68.1 LYM84 13403.1 H 0.089 8.80E−0459.1 LYM84 13403.3 H 0.07 9.00E−06 74.3 LYM136 13421.7 H 0.094 1.79E−0368.6 LYM84 13401.2 H 0.065 2.60E−05 62.6 LYM84 13401.2 H 0.086 3.12E−0354.6 LYM136 13421.5 H 0.066 2.80E−05 65 LYM293 13392.2 H 0.093 3.73E−0366.4 LYM1 11603.2 H 0.062 3.00E−05 54.9 LYM160 13472.2 H 0.085 5.45E−0351.8 LYM84 13404.4 H 0.06 7.80E−05 48.6 LYM293 13391.9 H 0.084 2.09E−0250.7 LYM136 13423.2 H 0.061 1.90E−03 51.8 LYM293 13391.2 H 0.0782.83E−02 40.1 LYM1 11604.4 H 0.054 4.45E−03 35.4 LYM136 13423.2 H 0.0813.88E−02 44.5 LYM1 11602.1 H 0.053 1.86E−02 31.5 LYM160 13471.4 H 0.0756.82E−02 34.5 CONTROL — H 0.04 — 0 CONTROL — H 0.056 — 0 LYM84 13403.2 C1.027 1.40E−05 80.2 LYM136 13421.5 C 0.908 0.00E+00 100.7 LYM136 13423.1C 1.023 1.50E−05 79.7 LYM136 13421.8 C 0.873 0.00E+00 93.1 LYM13613421.8 C 1.028 7.30E−05 80.6 LYM293 13391.2 C 0.792 0.00E+00 75.2 LYM8413403.1 C 0.893 1.60E−04 56.8 LYM160 13472.1 C 0.721 1.00E−06 59.5 LYM8413403.3 C 0.867 6.59E−04 52.3 LYM84 13403.3 C 1.089 1.00E−06 140.8LYM136 13421.6 C 0.853 2.33E−03 49.8 LYM136 13423.2 C 0.831 3.00E−0683.8 LYM136 13423.2 C 0.864 3.27E−03 51.7 LYM293 13391.4 C 1.0713.00E−06 136.8 LYM1 11603.2 C 0.817 3.91E−03 43.4 LYM160 13471.1 C 0.7723.10E−05 70.6 LYM84 13401.2 C 0.804 4.08E−03 41.2 LYM84 13401.2 C 0.6923.40E−05 52.9 LYM1 11602.6 C 0.862 5.42E−03 51.3 LYM136 13423.4 C 0.7774.90E−05 71.7 LYM1 11601.1 C 0.789 1.01E−02 38.6 LYM160 13472.2 C 0.6721.41E−04 48.7 LYM1 11604.4 C 0.823 1.54E−02 44.5 LYM84 13403.1 C 0.6462.21E−04 42.9 LYM84 13404.4 C 0.734 2.94E−02 28.8 LYM293 13391.9 C 0.7632.73E−04 68.7 LYM1 11602.1 C 0.727 4.75E−02 27.6 LYM136 13421.7 C 0.7278.57E−04 60.7 LYM136 13421.5 C 0.715 7.12E−02 25.5 LYM293 13392.2 C0.668 1.97E−02 47.8 CONTROL — C 0.57 — 0 CONTROL — C 0.452 — 0 LYM111604.4 E 0.583 3.46E−03 26.5 LYM84 13403.3 E 0.559 5.55E−02 23 LYM8413403.2 E 0.574 1.03E−02 24.6 CONTROL — E 0.454 — 0 LYM136 13421.8 E0.551 1.41E−02 19.7 LYM136 13421.8 D 7.685 9.00E−05 87.2 LYM84 13403.3 E0.562 1.74E−02 21.9 LYM136 13421.5 D 8.418 1.06E−04 105 LYM1 11601.1 E0.549 2.97E−02 19.1 LYM160 13472.1 D 6.28 5.37E−04 52.9 LYM84 13401.2 E0.543 4.13E−02 17.9 LYM293 13391.2 D 6.823 2.80E−03 66.1 LYM84 13403.1 E0.535 4.77E−02 16.1 LYM84 13403.1 D 5.88 8.55E−03 43.2 LYM84 13404.4 E0.528 5.27E−02 14.6 LYM84 13401.2 D 6.165 9.88E−03 50.1 LYM136 13423.2 E0.543 5.95E−02 18 LYM136 13423.2 D 7.685 1.61E−02 87.2 LYM1 11602.1 E0.525 6.56E−02 13.9 LYM160 13471.1 D 6.818 1.69E−02 66 CONTROL — E 0.461— 0 LYM84 13403.3 D 9.518 2.04E−02 131.8 LYM136 13423.1 D 8.863 8.70E−0575.8 LYM136 13423.4 D 7.015 2.44E−02 70.8 LYM84 13403.1 D 7.748 3.02E−0353.7 LYM160 13472.2 D 5.758 2.55E−02 40.2 LYM84 13403.2 D 8.738 5.76E−0373.4 LYM293 13391.4 D 9.49 2.56E−02 131.1 LYM84 13403.3 D 7.598 8.31E−0350.7 LYM293 13391.9 D 6.7 4.90E−02 63.2 LYM84 13401.2 D 7.038 9.19E−0339.6 LYM136 13421.7 D 6.533 5.11E−02 59.1 LYM84 13404.4 D 6.515 1.63E−0229.3 CONTROL — D 4.106 — 0 LYM1 11603.2 D 7.223 2.00E−02 43.3 LYM13613421.5 F 6.765 1.52E−03 21.7 LYM136 13421.8 D 8.993 2.33E−02 78.4LYM136 13423.2 F 6.73 2.68E−03 21.1 LYM1 11601.1 D 6.888 2.44E−02 36.7LYM136 13421.8 F 6.943 3.01E−03 24.9 LYM136 13421.6 D 7.335 3.72E−0245.5 LYM84 13401.2 F 6.2 9.41E−03 11.5 LYM136 13423.2 D 7.405 4.76E−0246.9 LYM136 13421.7 F 6.38 3.57E−02 14.8 LYM1 11602.6 D 7.605 4.83E−0250.9 LYM293 13391.9 F 6.223 4.78E−02 11.9 LYM1 11602.1 D 6.278 4.96E−0224.6 LYM84 13403.3 F 6.783 5.99E−02 22 CONTROL — D 5.04 — 0 LYM29313391.2 F 6.208 7.14E−02 11.7 LYM136 13421.8 F 7.018 1.11E−04 27.1LYM160 13471.1 F 6.125 9.99E−02 10.2 LYM84 13404.4 F 6.478 3.96E−04 17.3CONTROL — F 5.559 — 0 LYM136 13423.1 F 6.81 7.54E−04 23.3 LYM1 11601.1 F6.775 2.36E−03 22.7 LYM84 13403.3 F 6.765 3.61E−03 22.5 LYM84 13403.1 F6.53 4.49E−03 18.3 LYM84 13403.2 F 6.903 5.58E−03 25 LYM1 11603.2 F6.813 6.13E−03 23.4 LYM136 13423.2 F 6.79 7.54E−03 23 LYM84 13401.2 F6.633 1.04E−02 20.1 LYM1 11602.1 F 6.275 1.24E−02 13.7 LYM136 13421.6 F6.113 1.93E−02 10.7 LYM1 11604.4 F 6.708 2.78E−02 21.5 CONTROL — F 5.521— 0 Table 34. Results of the tissue culture experiments. Provided arethe measured values of each tested parameter [parameters (ID.) A-Faccording to the parameters described in Table 33 above] in plantsexpressing the indicated polynucleotides. “Ev” = event; “P” = P-value;“Mean” = the average of measured parameter across replicates. % incr.vs. cont. = percentage of increase versus control (as compared tocontrol).

TABLE 35 Measured parameters at the tissue culture assay (T1 experiment)for transformed agriculture improving trait genes Tested Parameters IDDry Weight (gr) A Fresh Weight (gr) B RGR Of Root Coverage C RootsCoverage TP3 (cm²) D RGR Of Roots Length E Roots Length TP3 (cm) F LeafArea TP3 (cm) G RGR Of Leaf Area H Leaf Area TP1 (cm) I Roots Length TP1(cm) J Table 35: Provided are the identification (ID) letters of each ofthe Tested Parameters. TP3 = Time point 3; RGR—relative growth rate. TP1= Time point 1.

TABLE 36 Results obtained in a T1 experiment at the tissue culture assay% incr. % incr. Gene name ID Mean P value vs. cont Gene name ID Mean Pvalue vs. cont LYM161 A 0.014 1.24E−03 90.4 LYM240 H 0.078 2.23E−02 31.2LYM219 A 0.01 2.07E−03 28.3 LYM228 H 0.077 2.59E−02 29.8 LYM83 A 0.011.93E−02 30.6 LYM189 H 0.076 3.81E−02 28 LYM278 A 0.009 3.67E−02 25.9LYM184 H 0.082 4.23E−02 37.8 LYM204 A 0.01 5.84E−02 36.3 LYM248 H 0.0766.24E−02 27.1 LYM155 A 0.013 6.05E−02 70.7 CONTROL H 0.06 — 0 LYM221 A0.009 9.70E−02 22.9 LYM117 A 0.009 5.26E−04 65.7 CONTROL — 0.007 — 0LYM146 A 0.01 1.17E−02 81.5 LYM161 B 0.282 9.40E−05 75.5 LYM144 A 0.0071.61E−02 34.3 LYM83 B 0.213 3.45E−03 32.5 LYM93 A 0.008 7.31E−02 43.5LYM219 B 0.207 2.66E−02 28.8 LYM123 A 0.006 7.96E−02 19 LYM204 B 0.2076.73E−02 28.8 LYM127 A 0.007 9.16E−02 32.1 LYM155 B 0.267 9.60E−02 66.3CONTROL A 0.005 — 0 LYM278 B 0.191 9.94E−02 18.9 LYM117 B 0.198 7.40E−0575.7 CONTROL — 0.161 — 0 LYM127 B 0.159 8.58E−04 41.3 LYM221 C 0.4681.90E−03 94.9 LYM146 B 0.186 8.64E−03 65.3 LYM155 C 0.468 2.86E−03 95.2LYM192 B 0.148 1.44E−02 31.7 LYM161 C 0.484 3.41E−03 101.5 LYM144 B0.153 4.48E−02 35.5 LYM188 C 0.4 2.12E−02 66.5 LYM93 B 0.172 5.30E−0252.3 LYM144 C 0.355 9.94E−02 48.1 LYM135 B 0.178 5.72E−02 58 CONTROL —0.24 — 0 LYM123 B 0.156 5.80E−02 38.4 LYM188 D 3.425 1.59E−03 67.6LYM200 B 0.153 6.00E−02 35.5 LYM221 D 3.964 1.79E−03 94 CONTROL B 0.113— 0 LYM155 D 3.85 1.26E−02 88.4 LYM135 C 0.625 1.90E−05 79.8 LYM144 D3.038 4.84E−02 48.6 LYM127 C 0.614 5.30E−05 76.4 LYM161 D 4.023 7.69E−0296.8 LYM146 C 0.553 1.54E−04 58.8 CONTROL — 2.044 — 0 LYM117 C 0.5375.03E−04 54.2 LYM155 E 0.444 9.80E−03 58.2 LYM154 C 0.56 1.78E−03 60.9LYM221 E 0.413 2.08E−02 47 LYM192 C 0.492 3.37E−03 41.5 LYM188 E 0.412.14E−02 46.1 LYM93 C 0.477 8.26E−03 37 LYM161 E 0.412 2.44E−02 46.6LYM200 C 0.483 9.48E−03 38.9 LYM144 E 0.405 2.83E−02 44.2 LYM144 C 0.4731.14E−02 35.8 CONTROL — 0.281 — 0 LYM123 C 0.473 1.75E−02 35.8 LYM188 F4.053 6.86E−04 41.3 LYM273 C 0.473 1.83E−02 35.8 LYM144 F 3.97 2.09E−0338.4 CONTROL C 0.348 — 0 LYM221 F 4.058 3.24E−03 41.5 LYM192 D 4.2171.10E−03 42.2 LYM161 F 3.914 2.30E−02 36.5 LYM93 D 4.075 1.12E−03 37.4LYM278 F 3.493 5.26E−02 21.8 LYM144 D 4.057 4.97E−03 36.8 LYM155 F 4.0845.40E−02 42.4 LYM117 D 4.4 7.86E−03 48.4 LYM204 F 3.68 6.02E−02 28.3LYM146 D 4.555 9.70E−03 53.6 CONTROL — 2.868 — 0 LYM200 D 4.151 3.73E−0240 LYM83 G 0.883 2.63E−04 31.7 LYM135 D 5.162 4.62E−02 74 LYM161 G 1.1291.06E−03 68.3 LYM127 D 5.078 5.37E−02 71.2 LYM221 G 0.856 4.40E−03 27.7LYM123 D 4.062 7.29E−02 37 LYM278 G 0.834 9.29E−03 24.3 CONTROL D 2.966— 0 LYM155 G 1.024 2.05E−02 52.8 LYM127 E 0.535 9.11E−04 48.7 LYM144 G0.823 3.31E−02 22.7 LYM135 E 0.508 2.21E−03 41 LYM204 G 0.789 4.70E−0217.6 LYM117 E 0.463 1.53E−02 28.7 CONTROL — 0.671 — 0 LYM93 E 0.4482.20E−02 24.5 LYM161 H 0.122 4.00E−06 71.4 LYM192 E 0.444 3.60E−02 23.2LYM155 H 0.112 2.07E−04 56.9 LYM154 E 0.456 4.57E−02 26.7 LYM83 H 0.0967.84E−03 35.1 CONTROL E 0.36 — 0 LYM278 H 0.09 3.91E−02 26.5 LYM93 F4.431 8.92E−04 21.7 LYM221 H 0.089 4.80E−02 25.3 LYM192 F 4.435 9.73E−0321.8 LYM144 H 0.088 6.23E−02 23.8 LYM144 F 4.132 6.49E−02 13.5 CONTROL —0.071 — 0 LYM123 F 4.108 7.42E−02 12.8 LYM227 A 0.01 8.00E−05 53.1LYM135 F 4.683 9.16E−02 28.6 LYM32 A 0.007 1.81E−03 19.8 CONTROL F 3.641— 0 LYM40 A 0.009 1.92E−03 49.9 LYM127 G 0.72 6.12E−04 22.6 LYM273 A0.009 2.65E−03 44.7 LYM117 G 0.904 2.69E−03 53.9 LYM273 A 0.01 3.12E−0363.1 LYM192 G 0.701 3.05E−03 19.3 LYM200 A 0.01 8.53E−03 57.9 LYM135 G0.885 1.05E−02 50.7 LYM118 A 0.008 2.84E−02 24.2 LYM146 G 0.854 1.87E−0245.4 LYM164 A 0.009 3.85E−02 39.1 LYM144 G 0.693 2.45E−02 18 LYM23 A0.008 6.86E−02 32.3 LYM93 G 0.737 9.00E−02 25.4 LYM93 A 0.01 8.67E−0261.9 CONTROL G 0.588 — 0 LYM122 A 0.008 9.35E−02 28.3 LYM117 H 0.0951.50E−05 62.9 CONTROL — 0.006 — 0 LYM135 H 0.09 4.07E−04 55.5 LYM227 B0.248 4.10E−05 47.9 LYM146 H 0.085 9.67E−04 46.9 LYM40 B 0.216 2.49E−0428.6 LYM93 H 0.075 2.94E−02 29.7 LYM273 B 0.231 7.82E−03 37.8 LYM127 H0.073 7.67E−02 25.7 LYM200 B 0.251 1.45E−02 49.8 CONTROL H 0.058 — 0LYM146 B 0.229 1.83E−02 36.6 LYM180 A 0.006 1.39E−04 44.3 LYM273 B 0.2491.90E−02 48.6 LYM243 A 0.006 3.56E−03 64.4 LYM164 B 0.222 2.09E−02 32.2LYM194 A 0.006 9.85E−03 62.5 LYM154 B 0.216 3.87E−02 28.8 LYM221 A 0.0054.06E−02 34.6 LYM122 B 0.189 6.35E−02 12.9 LYM204 A 0.006 4.55E−02 60.5LYM135 B 0.197 7.69E−02 17.4 LYM109 A 0.005 6.49E−02 29.4 CONTROL —0.168 — 0 LYM233 A 0.007 7.12E−02 70.9 LYM234 C 0.482 5.87E−02 32.1CONTROL A 0.004 — 0 LYM200 C 0.469 6.18E−02 28.7 LYM243 B 0.148 1.67E−0228.8 LYM227 C 0.47 6.80E−02 28.9 CONTROL B 0.115 — 0 LYM154 C 0.4817.23E−02 31.9 LYM233 C 0.383 4.28E−04 55.4 CONTROL — 0.364 — 0 LYM204 C0.377 6.67E−04 52.8 LYM200 D 3.874 5.17E−02 27.9 LYM248 C 0.377 1.32E−0353.1 CONTROL — 3.029 — 0 LYM194 C 0.366 1.66E−03 48.4 LYM273 G 1.0571.01E−04 23 LYM186 C 0.387 1.93E−03 57.1 LYM227 G 1.033 1.50E−04 20.2LYM243 C 0.347 4.89E−03 40.9 LYM200 G 1.012 2.71E−04 17.8 LYM83 C 0.3495.96E−03 41.5 LYM273 G 1.027 2.79E−04 19.6 LYM109 C 0.34 1.16E−02 38LYM154 G 1.022 1.12E−02 18.9 LYM228 C 0.336 1.95E−02 36.4 LYM164 G 1.0278.89E−02 19.5 LYM115 C 0.339 1.96E−02 37.7 LYM146 G 1.063 8.89E−02 23.7LYM252 C 0.34 2.33E−02 38 LYM40 G 0.97 9.15E−02 12.9 CONTROL C 0.246 — 0LYM135 G 1.045 9.75E−02 21.6 LYM243 D 2.941 4.12E−03 38.7 CONTROL —0.859 — 0 LYM115 D 2.938 6.77E−03 38.6 LYM93 H 0.117 2.44E−02 29.7LYM194 D 3.087 8.47E−03 45.6 LYM146 H 0.112 3.08E−02 24.4 LYM233 D 3.2841.36E−02 54.9 LYM273 H 0.108 4.22E−02 20.3 LYM204 D 3.176 2.25E−02 49.8LYM273 H 0.107 5.78E−02 19 LYM83 D 2.959 3.59E−02 39.6 LYM154 H 0.1086.06E−02 19.8 LYM109 D 2.886 4.28E−02 36.1 LYM164 H 0.108 6.30E−02 20LYM248 D 3.188 5.13E−02 50.4 LYM135 H 0.108 7.21E−02 19.8 CONTROL D 2.12— 0 LYM227 H 0.106 7.58E−02 17.7 LYM248 E 0.416 9.58E−03 27.1 LYM200 H0.106 7.94E−02 17.6 LYM204 E 0.389 6.24E−02 19.1 LYM234 H 0.107 8.46E−0218.6 LYM233 E 0.39 7.40E−02 19.4 CONTROL — 0.09 — 0 LYM83 E 0.3858.68E−02 17.7 LYM131 A 0.008 2.70E−02 60.5 CONTROL E 0.327 — 0 LYM194 A0.007 5.17E−02 36.9 LYM115 F 3.729 2.49E−03 13.6 LYM261 A 0.006 5.62E−0229.7 LYM248 F 4.115 5.82E−03 25.3 LYM185 A 0.01 5.77E−02 99.7 LYM228 F3.665 2.44E−02 11.6 LYM123 A 0.007 7.73E−02 39 LYM204 F 3.852 4.19E−0217.3 LYM192 A 0.006 7.80E−02 14.4 LYM83 F 3.788 6.51E−02 15.4 CONTROL —0.005 — 0 LYM233 F 3.97 8.99E−02 20.9 LYM252 B 0.165 5.43E−03 38.4CONTROL F 3.284 — 0 LYM131 B 0.181 2.17E−02 51.5 LYM233 G 0.768 5.26E−0341.5 LYM194 B 0.164 3.02E−02 37.5 LYM194 G 0.73 1.12E−02 34.5 LYM185 B0.225 3.55E−02 87.9 LYM228 G 0.597 4.27E−02 9.8 LYM123 B 0.154 4.39E−0228.9 LYM243 G 0.676 4.45E−02 24.5 CONTROL — 0.12 — 0 LYM215 G 0.6266.82E−02 15.4 LYM185 C 0.527 6.00E−06 97.4 LYM204 G 0.697 8.47E−02 28.3LYM123 C 0.495 1.50E−05 85.7 CONTROL G 0.543 — 0 LYM131 C 0.454 2.90E−0570.4 LYM233 H 0.078 1.07E−04 38.3 LYM194 C 0.413 1.09E−03 54.7 LYM194 H0.077 4.96E−04 36.3 LYM243 C 0.406 3.94E−03 52.1 LYM204 H 0.069 2.23E−0223.5 LYM252 C 0.375 1.15E−02 40.5 LYM243 H 0.068 2.43E−02 20.9 LYM233 C0.366 1.81E−02 37.2 LYM252 H 0.071 2.64E−02 26.5 LYM215 C 0.338 7.24E−0226.7 CONTROL H 0.056 — 0 CONTROL — 0.267 — 0 LYM189 A 0.009 3.27E−0432.5 LYM131 D 3.668 3.37E−04 67.4 LYM32 A 0.01 8.84E−03 51.3 LYM215 D2.788 1.33E−02 27.2 LYM219 A 0.01 4.76E−02 49.4 LYM194 D 3.34 2.15E−0252.4 LYM240 A 0.009 5.15E−02 33.2 LYM123 D 4.004 3.68E−02 82.7 LYM161 A0.01 7.76E−02 52 LYM185 D 4.257 5.21E−02 94.2 CONTROL A 0.007 — 0 LYM233D 3.014 6.12E−02 37.5 LYM32 B 0.19 9.39E−04 27.5 LYM252 D 3.036 7.43E−0238.5 LYM249 B 0.225 2.56E−03 51 CONTROL — 2.192 — 0 LYM189 B 0.213.29E−02 40.5 LYM131 E 0.469 8.00E−06 42.8 LYM193 B 0.193 6.69E−02 29.1LYM185 E 0.47 2.28E−04 43.1 LYM261 B 0.177 7.40E−02 18.5 LYM123 E 0.4483.49E−04 36.4 CONTROL B 0.149 — 0 LYM194 E 0.411 6.53E−03 25.3 LYM234 C0.531 0.00E+00 123.9 LYM243 E 0.407 8.35E−03 24 LYM249 C 0.539 0.00E+00127.6 LYM252 E 0.383 7.84E−02 16.6 LYM219 C 0.517 7.00E−06 118.2 CONTROL— 0.328 — 0 LYM240 C 0.415 2.30E−05 75.1 LYM131 F 4.042 7.90E−05 32LYM74 C 0.443 6.30E−05 86.9 LYM243 F 3.668 1.22E−02 19.8 LYM179 C 0.4061.06E−04 71.1 LYM215 F 3.383 3.49E−02 10.5 LYM161 C 0.409 1.34E−04 72.4LYM194 F 3.635 4.63E−02 18.8 LYM79 C 0.412 1.71E−04 73.6 LYM123 F 3.9125.09E−02 27.8 LYM188 C 0.38 5.35E−04 60.3 LYM185 F 4.091 7.35E−02 33.7LYM278 C 0.376 1.23E−03 58.5 CONTROL — 3.061 — 0 LYM261 C 0.369 1.75E−0355.6 LYM131 G 0.834 1.00E−06 54 LYM224 C 0.382 3.15E−03 61.3 LYM123 G0.78 2.30E−05 44.1 LYM189 C 0.349 5.89E−03 47.3 LYM233 G 0.643 8.49E−0318.8 LYM32 C 0.341 2.37E−02 44 LYM252 G 0.713 2.16E−02 31.8 LYM193 C0.322 4.86E−02 35.6 LYM243 G 0.656 2.67E−02 21.2 LYM155 C 0.302 9.72E−0227.2 LYM192 G 0.669 2.77E−02 23.5 CONTROL C 0.237 — 0 LYM261 G 0.6373.41E−02 17.7 LYM240 D 3.448 1.00E−06 67.3 LYM194 G 0.715 5.43E−02 32LYM188 D 3.137 6.00E−06 52.2 LYM185 G 0.825 5.58E−02 52.4 LYM179 D 3.359.72E−04 62.6 CONTROL — 0.541 — 0 LYM189 D 2.884 1.31E−03 39.9 LYM131 H0.087 3.00E−06 53.4 LYM234 D 4.399 4.93E−03 113.5 LYM185 H 0.0921.70E−05 62.1 LYM249 D 4.486 8.04E−03 117.7 LYM123 H 0.083 3.10E−05 46.2LYM74 D 3.651 9.49E−03 77.2 LYM252 H 0.077 2.13E−03 34.4 LYM261 D 3.072.24E−02 49 LYM194 H 0.077 3.63E−03 34.1 LYM161 D 3.381 2.29E−02 64.1LYM192 H 0.073 1.17E−02 27.3 LYM278 D 3.171 2.40E−02 53.9 LYM261 H 0.0694.77E−02 20.8 LYM79 D 3.427 3.04E−02 66.3 LYM243 H 0.068 7.19E−02 18.9LYM219 D 4.274 7.53E−02 107.4 CONTROL — 0.057 — 0 LYM155 D 2.5588.03E−02 24.1 LYM245 A 0.008 1.20E−02 38.7 CONTROL D 2.061 — 0 LYM228 A0.008 1.47E−02 44.3 LYM249 E 0.438 5.00E−06 53.9 LYM240 A 0.008 2.80E−0245.2 LYM234 E 0.431 3.10E−05 51.7 LYM260 A 0.007 3.74E−02 27.4 LYM219 E0.401 1.65E−03 41.2 LYM189 A 0.007 3.75E−02 27 LYM224 E 0.397 2.21E−0339.7 LYM184 A 0.009 5.19E−02 49.1 LYM179 E 0.378 3.93E−03 33 CONTROL —0.006 — 0 LYM79 E 0.383 5.24E−03 34.7 LYM245 B 0.16 1.51E−02 41.9 LYM240E 0.362 8.54E−03 27.4 LYM260 B 0.15 2.23E−02 33 LYM74 E 0.373 9.36E−0331.3 LYM189 B 0.136 4.67E−02 20.6 LYM189 E 0.352 2.77E−02 23.9 LYM240 B0.144 5.98E−02 27.5 LYM261 E 0.35 3.22E−02 23 LYM228 B 0.148 7.33E−0231.1 LYM188 E 0.352 3.95E−02 23.9 LYM184 B 0.159 8.46E−02 41.5 LYM193 E0.351 5.12E−02 23.4 CONTROL — 0.113 — 0 LYM161 E 0.348 5.53E−02 22.4LYM184 C 0.46 1.23E−03 98.6 LYM32 E 0.344 8.20E−02 21 LYM240 C 0.3636.06E−03 56.9 LYM251 E 0.338 9.37E−02 18.9 LYM109 C 0.33 2.96E−02 42.4CONTROL E 0.284 — 0 LYM245 C 0.322 5.20E−02 39.3 LYM74 F 3.635 3.70E−0518.8 LYM248 C 0.323 5.28E−02 39.7 LYM249 F 4.232 3.54E−03 38.3 LYM189 C0.318 6.19E−02 37.2 LYM240 F 3.548 3.55E−03 16 LYM186 C 0.315 6.33E−0236 LYM234 F 4.189 3.00E−02 36.9 CONTROL — 0.232 — 0 LYM261 F 3.4644.23E−02 13.2 LYM109 D 2.67 9.12E−04 41.4 LYM179 F 3.591 9.25E−02 17.4LYM186 D 2.588 1.06E−02 37 CONTROL F 3.06 — 0 LYM240 D 2.99 1.63E−0258.4 LYM240 G 0.919 5.00E−06 57.4 LYM189 D 2.592 1.94E−02 37.3 LYM249 G0.849 1.20E−05 45.4 LYM245 D 2.594 4.12E−02 37.4 LYM278 G 0.879 9.10E−0550.5 LYM115 D 2.352 4.59E−02 24.6 LYM261 G 0.799 1.65E−04 36.8 LYM248 D2.622 7.42E−02 38.8 LYM224 G 0.739 2.43E−04 26.5 LYM180 D 2.304 7.43E−0222 LYM189 G 0.853 1.11E−03 46 CONTROL — 1.888 — 0 LYM161 G 0.9131.62E−03 56.3 LYM240 E 0.391 1.32E−02 29.6 LYM79 G 0.915 2.06E−03 56.7LYM248 E 0.386 2.03E−02 28.1 LYM188 G 0.747 1.25E−02 27.9 LYM186 E 0.3842.65E−02 27.4 LYM219 G 0.841 1.69E−02 44.1 LYM184 E 0.417 5.28E−02 38.2LYM74 G 0.762 1.99E−02 30.4 LYM180 E 0.366 6.72E−02 21.5 LYM179 G 0.7954.21E−02 36.2 LYM109 E 0.364 7.31E−02 20.8 LYM234 G 0.815 4.73E−02 39.5CONTROL — 0.301 — 0 CONTROL G 0.584 — 0 LYM240 F 3.576 2.32E−03 26.9LYM161 H 0.097 2.10E−05 62.6 LYM109 F 3.246 1.05E−02 15.2 LYM240 H 0.0944.70E−05 57.3 LYM248 F 3.449 1.22E−02 22.4 LYM79 H 0.095 7.60E−05 59.9LYM180 F 3.271 3.14E−02 16 LYM189 H 0.091 1.67E−04 53.1 LYM186 F 3.5334.22E−02 25.3 LYM278 H 0.088 4.71E−04 47.7 LYM189 F 3.237 6.97E−02 14.8LYM249 H 0.086 7.09E−04 45.4 LYM115 F 3.16 7.89E−02 12.1 LYM219 H 0.0871.31E−03 46 CONTROL — 2.819 — 0 LYM234 H 0.086 2.25E−03 44.5 LYM184 G0.774 3.40E−05 36 LYM261 H 0.082 3.68E−03 38.3 LYM228 G 0.749 1.29E−0331.6 LYM32 H 0.086 4.72E−03 44.3 LYM189 G 0.726 6.50E−03 27.5 LYM179 H0.081 1.11E−02 35.5 LYM240 G 0.735 2.55E−02 29.1 LYM74 H 0.081 1.50E−0236.7 LYM186 G 0.653 4.33E−02 14.7 LYM188 H 0.077 2.66E−02 29.3 CONTROL —0.569 — 0 LYM224 H 0.077 4.09E−02 30.1 CONTROL H 0.059 — 0 LYM38 B 0.115— 13.8 LYM126 B 0.136 — 34.3 CONTROL B 0.101 — 0 LYM36 A 0.004 E−4.75016.7 LYM36 I 0.138 E−014.84 7.8 CONTROL A 0.004 — 0 CONTROL I 0.128 — 0LYM36 I 0.09 E−4.3401 7 LYM36 J 0.693 E−017.20 3.3 CONTROL I 0.084 — 0CONTROL J 0.671 — 0 Table 36. Results of the tissue culture experiments.Provided are the measured values of each tested parameter [parameters(ID.) A-F according to the parameters described in Table 35 above] inplants expressing the indicated polynucleotides. “Ev” = event; “P” =P-value; “Mean” = the average of measured parameter across events. %incr. vs. cont. = percentage of increase versus control (as compared tocontrol).

TABLE 37 Measured parameters at the tissue culture assay low nitrogen(T2 experiment) for transformed agriculture improving trait genes TestedParameters ID Dry Weight (gr) G Fresh Weight (gr) H RGR Of Root CoverageI Roots Coverage TP3 (cm²) J RGR Of Roots Length K Roots Length TP3 (cm)L Leaf Area TP3 (cm) M RGR Of Leaf Area N Table 37: Provided are theidentification (ID) letters of each of the Tested Parameters. TP3—TimePoint 3; RGR—Relative Growth Rate plants were grown on low nitrogen asdescribed above.

TABLE 38 Results obtained in a T2 experiment at the tissue culture assaylow nitrogen % incr. % incr. Gene name Event ID Mean P value vs. contGene name Event ID Mean P value vs. cont LYM178 12161.1 G 0.006 2.07E−0339.1 LYM5 12432.1 G 0.007 1.40E−05 69.3 LYM37 11801.2 G 0.007 3.50E−0360 LYM268 12483.2 G 0.007 1.56E−04 56.6 LYM34 11901.1 G 0.006 3.63E−0331.9 LYM1 11602.6 G 0.009 2.16E−04 107.8 CONTROL — G 0.004 — 0 LYM17812164.3 G 0.009 3.01E−03 110.2 LYM37 11801.2 I 1.024 1.65E−04 56.9LYM132 12275.3 G 0.006 3.52E−03 50.6 LYM178 12161.1 I 1.023 5.17E−0456.8 LYM129 12572.2 G 0.006 5.24E−03 41.6 CONTROL — I 0.652 — 0 LYM111604.4 G 0.006 5.89E−03 39.2 LYM12 11873.4 L 6.672 5.23E−03 23 LYM12912571.3 G 0.006 7.22E−03 45.2 LYM37 11801.2 L 6.593 5.54E−03 21.5 LYM26812483.4 G 0.008 7.89E−03 95.8 CONTROL — L 5.425 — 0 LYM178 12164.2 G0.006 8.14E−03 50.6 LYM5 12436.1 G 0.008 3.89E−04 83.5 LYM132 12273.2 G0.005 8.21E−03 30.7 LYM86 12183.3 G 0.007 5.67E−04 63 CONTROL — G 0.004— 0 LYM82 12203.5 G 0.011 2.31E−03 153 LYM1 11602.6 H 0.177 1.00E−06103.6 LYM82 12201.2 G 0.008 2.64E−03 77.8 LYM5 12432.1 H 0.142 1.94E−0464 LYM86 12182.3 G 0.007 2.83E−03 49.9 LYM268 12483.2 H 0.154 9.59E−0476.8 CONTROL — G 0.004 — 0 LYM129 12572.2 H 0.123 1.86E−03 41.4 LYM26812482.1 H 0.115 8.00E−06 61.6 LYM132 12275.3 H 0.144 2.77E−03 66.3 LYM8212203.5 H 0.189 2.40E−04 166 LYM129 12573.5 H 0.13 3.59E−03 50.2 LYM4411884.1 H 0.12 6.61E−04 67.8 LYM6 11735.1 H 0.118 8.04E−03 36 LYM611735.2 H 0.102 6.94E−04 43.6 LYM178 12164.2 H 0.133 9.56E−03 53.6 LYM8212201.2 H 0.144 1.47E−03 101.5 CONTROL — H 0.087 — 0 LYM129 12573.1 H0.122 1.54E−03 71.9 LYM268 12483.4 I 1.459 0.00E+00 94.9 LYM86 12183.3 H0.132 1.66E−03 85.3 LYM5 12435.1 I 1.327 5.00E−06 77.2 LYM86 12182.3 H0.124 2.94E−03 73.7 LYM178 12164.3 I 1.39 2.60E−05 85.7 LYM5 12436.1 H0.155 6.44E−03 118.2 LYM129 12571.3 I 1.264 3.90E−05 68.7 LYM129 12572.2H 0.121 7.61E−03 69.9 LYM129 12573.5 I 1.215 4.60E−05 62.3 LYM82 12204.6H 0.091 9.35E−03 27.4 LYM268 12483.2 I 1.195 7.50E−05 59.5 LYM5 12435.1H 0.104 9.36E−03 45.6 LYM268 12482.3 I 1.16 3.42E−04 54.9 LYM8 11984.1 H0.15 9.54E−03 110.2 LYM134 12314.2 I 1.199 4.26E−04 60.1 CONTROL — H0.071 — 0 LYM1 11603.2 I 1.094 1.02E−03 46.1 LYM268 12483.4 I 1.5150.00E+00 124.3 LYM5 12432.2 I 1.082 2.26E−03 44.5 LYM82 12203.2 I 1.4590.00E+00 116 LYM268 12482.1 I 1.23 4.74E−03 64.3 LYM82 12203.5 I 1.4198.00E−06 110.1 LYM1 11602.6 I 1.073 6.12E−03 43.2 LYM8 11984.1 I 1.3361.10E−05 97.9 LYM132 12276.1 I 1.134 7.20E−03 51.5 LYM44 11882.1 I 1.1352.40E−05 68.1 CONTROL — I 0.749 — 0 LYM5 12436.1 I 1.264 3.40E−05 87.2LYM268 12483.4 J 12.19 3.00E−05 90.2 LYM86 12183.3 I 1.056 1.39E−04 56.3LYM5 12435.1 J 10.945 1.14E−03 70.8 LYM86 12182.3 I 1.219 1.86E−04 80.5LYM129 12571.3 J 10.375 1.25E−03 61.9 LYM5 12436.2 I 1.072 2.95E−04 58.7LYM129 12573.5 J 10.093 2.32E−03 57.5 LYM82 12201.2 I 0.986 3.76E−04 46LYM268 12483.2 J 9.908 2.57E−03 54.6 LYM44 11884.3 I 1.094 5.32E−04 62LYM268 12482.3 J 9.59 4.95E−03 49.6 LYM44 11885.4 I 1.249 1.21E−03 85CONTROL — J 6.409 — 0 LYM268 12484.2 I 1.147 1.40E−03 69.9 LYM12912571.3 K 0.76 6.00E−05 41.4 LYM8 11982.7 I 0.958 1.62E−03 41.9 LYM512435.1 K 0.754 6.90E−05 40.3 LYM8 11983.1 I 1.007 1.85E−03 49.1 CONTROL— K 0.538 — 0 LYM129 12573.1 I 0.935 2.77E−03 38.4 LYM129 12571.3 L7.821 3.52E−04 23.6 LYM129 12573.3 I 0.901 2.85E−03 33.4 LYM5 12435.1 L7.76 5.05E−04 22.6 LYM268 12482.1 I 0.992 3.37E−03 46.9 LYM268 12483.4 L7.69 6.12E−04 21.5 LYM6 11734.3 I 1.105 5.28E−03 63.6 CONTROL — L 6.328— 0 LYM5 12435.1 I 1.047 6.27E−03 55.1 LYM5 12432.1 M 0.837 3.00E−0667.1 LYM129 12572.2 I 0.97 7.93E−03 43.6 LYM129 12571.3 M 0.732 2.50E−0546.1 CONTROL — I 0.675 — 0 LYM132 12273.2 M 0.685 8.40E−05 36.7 LYM8212203.2 J 12.328 1.84E−03 118.3 LYM1 11604.4 M 0.692 1.78E−04 38.1LYM129 12573.3 J 7.459 3.21E−03 32.1 LYM129 12573.5 M 0.797 3.26E−0459.1 LYM268 12483.4 J 12.726 6.83E−03 125.4 LYM178 12163.3 M 0.6686.70E−04 33.4 LYM82 12201.2 J 8.641 8.55E−03 53 LYM1 11602.6 M 0.957.84E−04 89.7 CONTROL — J 5.647 — 0 LYM5 12435.1 M 0.756 8.12E−04 51.1LYM82 12203.2 K 0.636 1.22E−03 30 LYM132 12275.3 M 0.727 1.36E−03 45.3LYM5 12435.1 K 0.624 1.73E−03 27.8 LYM1 11602.1 M 0.676 1.74E−03 35.1LYM86 12182.3 K 0.622 2.13E−03 27.3 LYM268 12483.4 M 0.889 2.41E−03 77.5LYM268 12483.4 K 0.628 3.66E−03 28.5 LYM178 12164.3 M 0.93 2.60E−03 85.7LYM44 11884.3 K 0.614 5.55E−03 25.7 LYM178 12164.2 M 0.732 4.37E−03 46.3CONTROL — K 0.489 — 0 LYM129 12572.2 M 0.7 5.37E−03 39.9 LYM82 12203.2 L7.098 1.50E−05 35.2 LYM134 12314.2 M 0.746 5.84E−03 48.9 LYM86 12182.3 L6.996 2.30E−05 33.3 LYM1 11603.2 M 0.78 9.55E−03 55.8 LYM268 12483.4 L7.232 2.69E−04 37.8 CONTROL — M 0.501 — 0 LYM5 12435.1 L 6.758 3.03E−0428.7 LYM1 11602.6 N 0.098 0.00E+00 96 LYM82 12203.5 L 7.346 4.61E−0439.9 LYM178 12164.3 N 0.094 0.00E+00 87 LYM86 12183.3 L 6.532 8.44E−0424.4 LYM268 12483.4 N 0.092 0.00E+00 83.5 LYM5 12432.1 L 6.265 1.21E−0319.3 LYM5 12432.1 N 0.083 1.00E−06 65.1 LYM5 12436.1 L 6.713 1.40E−0327.9 LYM5 12435.1 N 0.083 6.00E−06 65.5 LYM44 11884.3 L 6.768 1.41E−0328.9 LYM129 12573.5 N 0.08 7.00E−06 60.5 LYM268 12484.2 L 6.748 3.26E−0328.5 LYM1 11603.2 N 0.082 1.10E−05 64.2 LYM44 11885.4 L 6.724 3.68E−0328.1 LYM129 12571.3 N 0.076 2.30E−05 52.5 LYM8 11983.1 L 6.614 5.58E−0326 LYM178 12164.2 N 0.078 3.10E−05 55.3 LYM5 12436.2 L 6.52 6.08E−0324.2 LYM132 12275.3 N 0.073 7.30E−05 45.8 LYM86 12181.3 L 6.239 6.93E−0318.8 LYM132 12273.2 N 0.071 8.20E−05 41.5 LYM8 11984.1 L 6.951 8.05E−0332.4 LYM132 12276.1 N 0.076 1.27E−04 52.1 CONTROL — L 5.25 — 0 LYM111604.4 N 0.071 1.52E−04 41 LYM82 12203.2 M 0.836 8.30E−05 110.7 LYM512432.2 N 0.077 1.63E−04 53.8 LYM129 12572.2 M 0.675 4.28E−04 69.9LYM268 12482.1 N 0.082 1.98E−04 63 LYM268 12482.1 M 0.63 6.12E−04 58.6LYM129 12572.2 N 0.072 2.38E−04 44.1 LYM82 12203.5 M 0.836 9.33E−04110.6 LYM134 12313.2 N 0.084 2.41E−04 67.5 LYM86 12183.3 M 0.6841.14E−03 72.2 LYM134 12314.2 N 0.073 6.27E−04 45.5 LYM82 12204.6 M 0.4911.31E−03 23.6 LYM268 12483.2 N 0.077 1.02E−03 52.9 LYM82 12201.2 M 0.7871.98E−03 98.1 LYM1 11602.1 N 0.068 1.34E−03 36.8 LYM268 12483.4 M 0.8252.72E−03 107.9 LYM132 12271.4 N 0.075 2.22E−03 49.5 LYM5 12436.1 M 0.7763.22E−03 95.3 LYM178 12163.3 N 0.064 7.09E−03 26.9 LYM268 12484.2 M0.743 4.16E−03 87.2 LYM1 11601.1 N 0.067 8.58E−03 34.4 LYM8 11984.1 M0.716 4.66E−03 80.3 CONTROL — N 0.05 — 0 LYM8 11982.7 M 0.565 8.97E−0342.3 LYM5 12435.1 M 0.674 9.05E−03 69.7 LYM86 12182.3 M 0.719 9.47E−0381.2 LYM268 12481.1 M 0.627 9.53E−03 58 CONTROL — M 0.397 — 0 LYM26812483.4 N 0.085 0.00E+00 112.8 LYM82 12203.2 N 0.088 0.00E+00 119.9LYM82 12203.5 N 0.087 0.00E+00 116.8 LYM5 12436.1 N 0.078 1.00E−06 95.5LYM82 12201.2 N 0.074 2.00E−06 85 LYM8 11984.1 N 0.075 3.00E−06 87 LYM8612183.3 N 0.072 3.00E−06 80.7 LYM129 12573.1 N 0.073 1.00E−05 82.5LYM268 12484.2 N 0.073 1.20E−05 82.9 LYM86 12182.3 N 0.074 2.00E−05 85.7LYM5 12435.1 N 0.072 2.60E−05 80.5 LYM268 12482.1 N 0.066 6.90E−05 63.7LYM129 12572.2 N 0.068 8.00E−05 71.2 LYM268 12481.3 N 0.066 8.40E−05 64LYM44 11884.3 N 0.067 9.10E−05 68 LYM268 12481.1 N 0.062 4.98E−04 54.5LYM44 11885.4 N 0.068 5.74E−04 70.9 LYM5 12436.2 N 0.062 9.56E−04 55.4LYM8 11982.7 N 0.059 1.14E−03 47 LYM44 11884.1 N 0.057 2.22E−03 42 LYM811982.4 N 0.057 2.75E−03 42.3 LYM82 12201.1 N 0.056 5.28E−03 39 LYM8612183.1 N 0.056 7.02E−03 40.5 LYM44 11885.3 N 0.059 7.80E−03 46.7 LYM4411882.1 N 0.056 8.64E−03 40.3 CONTROL — N 0.04 — 0 LYM136 13423.2 H0.006 2.00E−06 107.3 LYM136 13423.2 N 0.085 0.00E+00 82.6 LYM136 13421.8G 0.005 8.66E−04 75.6 LYM136 13421.8 N 0.082 0.00E+00 75.9 LYM84 13404.4G 0.007 2.84E−03 113.8 LYM84 13404.4 N 0.092 0.00E+00 96.7 LYM13613421.6 G 0.006 2.89E−03 94.3 LYM84 13401.2 N 0.088 0.00E+00 88 LYM111601.1 G 0.005 5.24E−03 61 LYM1 11601.1 N 0.081 1.00E−06 73.2 LYM8413403.3 G 0.006 5.30E−03 87.8 LYM84 13403.3 N 0.08 2.00E−06 70.6 LYM8413401.2 G 0.007 5.52E−03 130.9 LYM84 13403.2 N 0.073 2.00E−06 55.9 LYM111603.2 G 0.004 9.31E−03 42.3 LYM136 13423.1 N 0.085 3.00E−06 81.3 LYM8413403.2 G 0.005 1.53E−02 58.5 LYM1 11602.6 N 0.07 1.40E−05 49.8 LYM111602.6 G 0.005 2.06E−02 50.4 LYM136 13421.6 N 0.075 2.50E−05 60.5LYM136 13423.1 G 0.007 3.33E−02 123.6 LYM84 13403.1 N 0.07 7.20E−05 50.5LYM136 13421.5 G 0.005 5.81E−02 72.4 LYM136 13421.5 N 0.074 1.10E−0457.9 CONTROL — G 0.003 — 0 LYM1 11603.2 N 0.071 1.87E−04 51.2 LYM111601.1 H 0.103 1.93E−04 78.3 LYM1 11604.4 N 0.058 2.56E−02 23.7 LYM8413403.3 H 0.11 1.55E−03 91.3 LYM1 11602.1 N 0.056 7.26E−02 19.1 LYM8413403.2 H 0.113 1.81E−03 95.7 CONTROL — N 0.047 — 0 LYM136 13423.2 H0.13 4.05E−03 126.1 LYM136 13421.8 I 1.163 9.90E−05 51.6 LYM1 11603.2 H0.093 4.55E−03 60.9 LYM136 13423.1 I 1.209 8.12E−04 57.6 LYM84 13404.4 H0.13 6.79E−03 126.1 LYM1 11603.2 I 0.993 1.65E−03 29.4 LYM1 11602.6 H0.103 7.66E−03 78.3 LYM84 13404.4 I 1.095 2.56E−03 42.7 LYM136 13423.1 H0.148 9.13E−03 156.5 LYM84 13403.2 I 1.009 3.97E−03 31.5 LYM136 13421.8H 0.128 1.35E−02 121.7 LYM84 13403.1 I 0.997 4.57E−03 30 LYM84 13401.2 H0.133 1.58E−02 130.4 LYM136 13423.2 I 1.104 4.86E−03 43.9 LYM136 13421.5H 0.105 2.31E−02 82.6 LYM84 13403.3 I 1.035 8.51E−03 34.9 LYM136 13421.6H 0.11 2.99E−02 91.3 LYM84 13401.2 I 1.049 2.01E−02 36.8 LYM84 13403.1 H0.095 9.17E−02 65.2 LYM136 13421.6 I 0.996 2.96E−02 29.8 CONTROL — H0.058 — 0 LYM1 11601.1 I 0.899 6.99E−02 17.1 LYM136 13421.8 M 0.8050.00E+00 84 LYM1 11604.4 I 0.884 9.29E−02 15.3 LYM84 13403.2 M 0.6830.00E+00 56 CONTROL — I 0.767 — 0 LYM1 11602.6 M 0.713 1.50E−04 62.9LYM1 11603.2 J 8.538 1.59E−03 30 LYM84 13404.4 M 0.893 6.76E−04 104LYM84 13403.1 J 8.743 1.76E−02 33.1 LYM1 11601.1 M 0.84 7.01E−04 92LYM136 13421.8 J 10.115 2.04E−02 54 LYM136 13423.2 M 0.835 7.48E−04 90.9LYM84 13403.2 J 8.468 3.82E−02 28.9 LYM84 13403.1 M 0.675 1.60E−03 54.3LYM84 13404.4 J 9.658 5.32E−02 47 LYM84 13403.3 M 0.79 2.37E−03 80.6LYM1 11604.4 J 7.745 5.47E−02 17.9 LYM84 13401.2 M 0.86 2.92E−03 96.6LYM136 13423.1 J 10.398 6.40E−02 58.3 LYM136 13423.1 M 0.84 4.59E−03 92LYM1 11601.1 J 7.858 6.86E−02 19.6 LYM1 11603.2 M 0.693 8.94E−03 58.3CONTROL — J 6.568 — 0 LYM136 13421.6 M 0.738 9.38E−03 68.6 LYM13613421.8 L 7.173 1.89E−03 21.6 LYM1 11604.4 M 0.54 1.15E−02 23.4 LYM8413404.4 L 7.105 3.22E−03 20.4 LYM136 13421.5 M 0.685 1.62E−02 56.6 LYM8413403.1 L 6.823 8.12E−03 15.7 LYM1 11602.1 M 0.538 5.30E−02 22.9 LYM111603.2 L 6.868 9.56E−03 16.4 CONTROL — M 0.438 — 0 LYM1 11601.1 L 6.5382.95E−02 10.8 LYM136 13423.2 L 6.88 3.42E−02 16.6 LYM84 13403.2 L 6.4457.62E−02 9.3 CONTROL — L 5.899 — 0 Table 38. Results of the tissueculture T2 experiments. Provided are the measured values of each testedparameter [parameters (ID.) G-L according to the parameters described inTable 37 above] in plants expressing the indicated polynucleotides. “Ev”= event; “P” = P-value; “Mean” = the average of measured parameteracross events. % incr. vs. cont. = percentage of increase versus control(as compared to control).

These results demonstrate that the polynucleotides of the invention arecapable of improving yield and additional valuable importantagricultural traits such as increase of biomass, abiotic stresstolerance, nitrogen use efficiency, yield, vigor, fiber yield and/orquality. Thus, transformed plants showing improved fresh and dry weightdemonstrate the gene capacity to improve biomass a key trait of cropsfor forage and plant productivity; transformed plants showingimprovement of seed yield demonstrate the genes capacity to improveplant productivity; transformed plants showing improvement of plotcoverage and rosette diameter demonstrate the genes capacity to improveplant drought resistance as they reduce the loss of soil water by simpleevaporation and reduce the competition with weeds; hence reduce the needto use herbicides to control weeds. Transformed plants showingimprovement of relative growth rate of various organs (leaf and root)demonstrate the gene capacity to promote plant growth and henceshortening the needed growth period and/or alternatively improving theutilization of available nutrients and water leading to increase of landproductivity; Transformed plants showing improvement of organ number asdemonstrated by the leaf number parameter exhibit a potential to improvebiomass yield important for forage crops and improve the plantproductivity; Transformed plants showing increased root length andcoverage demonstrate the gene capacity to improve drought resistance andbetter utilization of fertilizers as the roots can reach larger soilvolume; Transformed plants showing improvement of leaf petiole relativearea and leaf blade area demonstrate the genes capacity to cope withlimited light intensities results from increasing the plant populationdensities and hence improve land productivity.

Although the invention has been described in conjunction with specificembodiments thereof, it is evident that many alternatives, modificationsand variations will be apparent to those skilled in the art.Accordingly, it is intended to embrace all such alternatives,modifications and variations that fall within the spirit and broad scopeof the appended claims.

All publications, patents and patent applications mentioned in thisspecification are herein incorporated in their entirety by referenceinto the specification, to the same extent as if each individualpublication, patent or patent application was specifically andindividually indicated to be incorporated herein by reference. Inaddition, citation or identification of any reference in thisapplication shall not be construed as an admission that such referenceis available as prior art to the present invention. To the extent thatsection headings are used, they should not be construed as necessarilylimiting.

What is claimed is:
 1. A method of increasing a trait of a plant ascompared to a non-transformed plant of the same species, the trait isselected from the group consisting of: rosette area, rosette diameter,and growth rate of rosette area, the method comprising: (a) expressingwithin the plant an exogenous polynucleotide comprising a nucleic acidsequence encoding the polypeptide set forth in SEQ ID NO: 246, whereinsaid exogenous polynucleotide is comprised within a nucleic acidconstruct and is operably linked to a plant promoter within said nucleicacid construct, and (b) selecting plants resulting from step (a) for anincreased trait selected from the group consisting of: rosette area,rosette diameter, and growth rate of rosette area, as compared to anon-transformed plant of the same species which is grown under the samegrowth conditions, thereby increasing the trait of the plant as comparedto a non-transformed plant of the same species.
 2. The method of claim1, wherein said exogenous polynucleotide comprises a nucleic acidsequence selected from the group consisting of SEQ ID NOs: 3487 and 7.3. A method of growing a crop comprising: (a) selecting a parent planttransformed with an exogenous polynucleotide comprising a nucleic acidsequence encoding the polypeptide set forth in SEQ ID NO: 246 for atleast one trait selected from the group consisting of: increased rosettearea, increased rosette diameter, and increased growth rate of rosettearea, as compared to a non-transformed plant of the same species whichis grown under the same growth conditions, wherein said exogenouspolynucleotide is comprised within a nucleic acid construct and isoperably linked to a plant promoter within said nucleic acid construct,and (b) growing progeny crop plant of said parent plant, wherein saidprogeny crop plant which comprises said exogenous polynucleotide hassaid increased rosette area, said increased rosette diameter, and/orsaid increased growth rate of rosette area, thereby growing the crop. 4.The method of claim 3, wherein said exogenous polynucleotide comprises anucleic acid sequence selected from the group consisting of SEQ ID NOs:3487 and
 7. 5. The method of claim 3, wherein said selecting said parentplant that has been transformed to express said exogenous polynucleotideis for increased rosette diameter as compared to a non-transformed plantof the same species which is grown under the same growth conditions. 6.The method of claim 3, wherein said selecting said parent plant that hasbeen transformed to express said exogenous polynucleotide is forincreased growth rate of rosette area as compared to a non-transformedplant of the same species which is grown under the same growthconditions.
 7. The method of claim 3, wherein said selecting said parentplant that has been transformed to express said exogenous polynucleotideis for increased rosette area as compared to a non-transformed plant ofthe same species which is grown under the same growth conditions.
 8. Amethod of selecting a plant having an increased trait selected from thegroup consisting of: rosette area, rosette diameter, and growth rate ofrosette area, as compared to a non-transformed plant of the same specieswhich is grown under the same growth conditions, the method comprising:(a) providing plants transformed with an exogenous polynucleotideencoding the polypeptide set forth in SEQ ID NO: 246, wherein saidexogenous polynucleotide is comprised within a nucleic acid constructand is operably linked to a plant promoter within said nucleic acidconstruct, (b) selecting said plants for increased rosette area, rosettediameter, and growth rate of rosette area, as compared to anon-transformed plant of the same species which is grown under the samegrowth condition, and (c) growing a crop of said plant selected in step(b), thereby selecting the plant having increased rosette area, rosettediameter, and growth rate of rosette area, as compared to thenon-transformed plant of the same species which is grown under the samegrowth conditions.
 9. The method of claim 8, wherein said exogenouspolynucleotide comprises a nucleic acid sequence selected from the groupconsisting of SEQ ID NOs: 3487 and
 7. 10. A method of producing seeds ofa crop comprising: (a) selecting parent plant transformed with anexogenous polynucleotide comprising a nucleic acid sequence encoding thepolypeptide set forth in SEQ ID NO: 246 for at least one trait selectedfrom the group consisting of: increased rosette area, increased rosettediameter, and increased growth rate of rosette area, as compared to anon-transformed plant of the same species which is grown under the samegrowth conditions, wherein said exogenous polynucleotide is comprisedwithin a nucleic acid construct and is operably linked to a plantpromoter within said nucleic acid construct, (b) growing a seedproducing plant from said parent plant resultant of step (a), whereinsaid seed producing plant which comprises said exogenous polynucleotidehaving said increased rosette area, said increased rosette diameter,and/or said increased growth rate of rosette area, and (c) producingseeds from said seed producing plant resultant of step (b), therebyproducing seeds of the crop.
 11. The method of claim 10, wherein saidexogenous polynucleotide comprises a nucleic acid sequence selected fromthe group consisting of SEQ ID NOs: 3487 and
 7. 12. The method of claim3, further comprising producing seeds from said progeny crop plantresultant of step (b).